JP6368247B2 - エーロゾル発生装置 - Google Patents

エーロゾル発生装置 Download PDF

Info

Publication number: JP6368247B2
Authority: JP; Japan
Prior art keywords: perforated plate; mandrel; plate; range; perforated
Prior art date: 2011-12-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

JP2014547972A

Other languages

English (en)

Japanese (ja)

Other versions

JP2015511988A (ja

Inventor

ホーガン，ブレンダン

ブタン，ダニエラ

クリフフォード，シェイマス

ポメロイ，マイケル

サウザン，マーク

シール，デヴィッド

Original Assignee

スタムフォード・ディバイセズ・リミテッド

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-12-21

Filing date

2012-12-19

Publication date

2018-08-01

2012-12-19 Application filed by スタムフォード・ディバイセズ・リミテッド filed Critical スタムフォード・ディバイセズ・リミテッド

2015-04-23 Publication of JP2015511988A publication Critical patent/JP2015511988A/ja

2018-08-01 Application granted granted Critical

2018-08-01 Publication of JP6368247B2 publication Critical patent/JP6368247B2/ja

Status Active legal-status Critical Current

2032-12-19 Anticipated expiration legal-status Critical

Links

239000000443 aerosol Substances 0.000 title claims description 11
KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims description 24
229910052763 palladium Inorganic materials 0.000 claims description 12
239000002245 particle Substances 0.000 claims description 12
PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 10
229910000990 Ni alloy Inorganic materials 0.000 claims description 9
229910052759 nickel Inorganic materials 0.000 claims description 5
239000013078 crystal Substances 0.000 claims 1
238000000034 method Methods 0.000 description 32
239000007788 liquid Substances 0.000 description 26
239000000243 solution Substances 0.000 description 15
239000007921 spray Substances 0.000 description 15
239000003814 drug Substances 0.000 description 14
229920002120 photoresistant polymer Polymers 0.000 description 14
229940079593 drug Drugs 0.000 description 13
239000000463 material Substances 0.000 description 9
238000012387 aerosolization Methods 0.000 description 7
239000010410 layer Substances 0.000 description 7
238000005323 electroforming Methods 0.000 description 5
238000004519 manufacturing process Methods 0.000 description 5
238000001000 micrograph Methods 0.000 description 5
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
229910052751 metal Inorganic materials 0.000 description 4
239000002184 metal Substances 0.000 description 4
239000012811 non-conductive material Substances 0.000 description 4
238000011282 treatment Methods 0.000 description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
238000001647 drug administration Methods 0.000 description 3
238000009713 electroplating Methods 0.000 description 3
238000010884 ion-beam technique Methods 0.000 description 3
238000007747 plating Methods 0.000 description 3
238000004088 simulation Methods 0.000 description 3
238000005507 spraying Methods 0.000 description 3
229920013683 Celanese Polymers 0.000 description 2
238000004458 analytical method Methods 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
230000004064 dysfunction Effects 0.000 description 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
150000002500 ions Chemical class 0.000 description 2
230000007257 malfunction Effects 0.000 description 2
239000012528 membrane Substances 0.000 description 2
239000007769 metal material Substances 0.000 description 2
210000002345 respiratory system Anatomy 0.000 description 2
238000005382 thermal cycling Methods 0.000 description 2
108010077544 Chromatin Proteins 0.000 description 1
GYHNNYVSQQEPJS-UHFFFAOYSA-N Gallium Chemical compound [Ga] GYHNNYVSQQEPJS-UHFFFAOYSA-N 0.000 description 1
102000004877 Insulin Human genes 0.000 description 1
108090001061 Insulin Proteins 0.000 description 1
208000019693 Lung disease Diseases 0.000 description 1
229910002669 PdNi Inorganic materials 0.000 description 1
102000015731 Peptide Hormones Human genes 0.000 description 1
108010038988 Peptide Hormones Proteins 0.000 description 1
NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 description 1
229940057282 albuterol sulfate Drugs 0.000 description 1
BNPSSFBOAGDEEL-UHFFFAOYSA-N albuterol sulfate Chemical compound OS(O)(=O)=O.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 BNPSSFBOAGDEEL-UHFFFAOYSA-N 0.000 description 1
229910045601 alloy Inorganic materials 0.000 description 1
239000000956 alloy Substances 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
238000005219 brazing Methods 0.000 description 1
210000003483 chromatin Anatomy 0.000 description 1
239000011248 coating agent Substances 0.000 description 1
238000000576 coating method Methods 0.000 description 1
230000007797 corrosion Effects 0.000 description 1
238000005260 corrosion Methods 0.000 description 1
238000001723 curing Methods 0.000 description 1
238000005520 cutting process Methods 0.000 description 1
125000004122 cyclic group Chemical group 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
238000000151 deposition Methods 0.000 description 1
238000009826 distribution Methods 0.000 description 1
238000004070 electrodeposition Methods 0.000 description 1
238000005868 electrolysis reaction Methods 0.000 description 1
238000005516 engineering process Methods 0.000 description 1
238000010304 firing Methods 0.000 description 1
229920005570 flexible polymer Polymers 0.000 description 1
229910052733 gallium Inorganic materials 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
238000002664 inhalation therapy Methods 0.000 description 1
230000000977 initiatory effect Effects 0.000 description 1
229940125396 insulin Drugs 0.000 description 1
OEXHQOGQTVQTAT-JRNQLAHRSA-N ipratropium Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 OEXHQOGQTVQTAT-JRNQLAHRSA-N 0.000 description 1
229960001888 ipratropium Drugs 0.000 description 1
210000004072 lung Anatomy 0.000 description 1
239000011259 mixed solution Substances 0.000 description 1
238000000465 moulding Methods 0.000 description 1
239000006199 nebulizer Substances 0.000 description 1
239000004033 plastic Substances 0.000 description 1
229920003023 plastic Polymers 0.000 description 1
239000002861 polymer material Substances 0.000 description 1
239000011148 porous material Substances 0.000 description 1
230000003389 potentiating effect Effects 0.000 description 1
230000002685 pulmonary effect Effects 0.000 description 1
230000000241 respiratory effect Effects 0.000 description 1
208000023504 respiratory system disease Diseases 0.000 description 1
229960002052 salbutamol Drugs 0.000 description 1
239000002356 single layer Substances 0.000 description 1
239000007787 solid Substances 0.000 description 1
238000000992 sputter etching Methods 0.000 description 1
239000010935 stainless steel Substances 0.000 description 1
229910001220 stainless steel Inorganic materials 0.000 description 1
238000007619 statistical method Methods 0.000 description 1
239000000725 suspension Substances 0.000 description 1
229940124597 therapeutic agent Drugs 0.000 description 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0638—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
- B05B17/0646—Vibrating plates, i.e. plates being directly subjected to the vibrations, e.g. having a piezoelectric transducer attached thereto
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0653—Details
- B05B17/0669—Excitation frequencies
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C5/00—Alloys based on noble metals
- C22C5/04—Alloys based on a platinum group metal
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
- C25D1/00—Electroforming
- C25D1/10—Moulds; Masks; Masterforms
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
- C25D3/00—Electroplating: Baths therefor
- C25D3/02—Electroplating: Baths therefor from solutions
- C25D3/56—Electroplating: Baths therefor from solutions of alloys
- C25D3/567—Electroplating: Baths therefor from solutions of alloys containing more than 50% by weight of platinum group metals

Landscapes

Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Materials Engineering (AREA)
Metallurgy (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Electrochemistry (AREA)
Mechanical Engineering (AREA)
Special Spraying Apparatus (AREA)
Nozzles (AREA)

JP2014547972A 2011-12-21 2012-12-19 エーロゾル発生装置 Active JP6368247B2 (ja)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US201161578645P	2011-12-21	2011-12-21
IE20110562		2011-12-21
US61/578,645		2011-12-21
IE2011/0562		2011-12-21
PCT/EP2012/076135 WO2013092701A1 (en)	2011-12-21	2012-12-19	Aerosol generators

Publications (2)

Publication Number	Publication Date
JP2015511988A JP2015511988A (ja)	2015-04-23
JP6368247B2 true JP6368247B2 (ja)	2018-08-01

Family

ID=48667754

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2014547972A Active JP6368247B2 (ja)	2011-12-21	2012-12-19	エーロゾル発生装置

Country Status (5)

Country	Link
EP (2)	EP3042982A1 (zh)
JP (1)	JP6368247B2 (zh)
CN (1)	CN104302813B (zh)
RU (1)	RU2014121781A (zh)
WO (1)	WO2013092701A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP3042982A1 (en) *	2011-12-21	2016-07-13	Stamford Devices Limited	Aerosol generators
KR101953970B1 (ko) *	2016-06-29	2019-03-05	동국대학교 경주캠퍼스 산학협력단	미세분무용 다공성 필터의 제조방법 및 이를 이용하여 제조된 다공성 필터

Family Cites Families (17)

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JPS493369B1 (zh) *	1963-10-01	1974-01-25
US4628165A (en) *	1985-09-11	1986-12-09	Learonal, Inc.	Electrical contacts and methods of making contacts by electrodeposition
US5164740A (en)	1991-04-24	1992-11-17	Yehuda Ivri	High frequency printing mechanism
US6205999B1 (en) *	1995-04-05	2001-03-27	Aerogen, Inc.	Methods and apparatus for storing chemical compounds in a portable inhaler
US5758637A (en)	1995-08-31	1998-06-02	Aerogen, Inc.	Liquid dispensing apparatus and methods
US5586550A (en)	1995-08-31	1996-12-24	Fluid Propulsion Technologies, Inc.	Apparatus and methods for the delivery of therapeutic liquids to the respiratory system
CN1042654C (zh) *	1995-06-28	1999-03-24	太原化学工业集团公司化肥厂	钯合金吸附网
US6235177B1 (en)	1999-09-09	2001-05-22	Aerogen, Inc.	Method for the construction of an aperture plate for dispensing liquid droplets
US6533394B1 (en) *	2001-08-29	2003-03-18	Hewlett-Packard Company	Orifice plate with break tabs and method of manufacturing
US20070097176A1 (en) *	2005-10-31	2007-05-03	Kenneth Hickey	Orifice plate coated with palladium nickel alloy
JP2010540526A (ja) *	2007-09-25	2010-12-24	ノバルティスアーゲー	エアロゾル化されたバンコマイシンのような薬剤での肺障害の処置
CN101637637B (zh) *	2009-06-08	2011-12-07	陕西坚瑞消防股份有限公司	一种热气溶胶灭火装置
CN101891253B (zh) *	2010-07-16	2012-08-22	中国原子能科学研究院	单分散微米级铀氧化物微粒的制备方法
CN102244976B (zh) *	2011-04-22	2013-07-31	杭州威利广光电科技股份有限公司	适于金线键合的bt线路板合金镀层
EP2607524B1 (en) *	2011-12-21	2014-09-10	Stamford Devices Limited	Aerosol generators
EP3042982A1 (en) *	2011-12-21	2016-07-13	Stamford Devices Limited	Aerosol generators
US9522409B2 (en) *	2011-12-21	2016-12-20	Stamford Devices Limited	Aerosol generators

2012
- 2012-12-19 EP EP16156955.3A patent/EP3042982A1/en not_active Withdrawn
- 2012-12-19 WO PCT/EP2012/076135 patent/WO2013092701A1/en active Application Filing
- 2012-12-19 RU RU2014121781A patent/RU2014121781A/ru not_active Application Discontinuation
- 2012-12-19 CN CN201280063802.6A patent/CN104302813B/zh active Active
- 2012-12-19 EP EP12812228.0A patent/EP2794964B1/en active Active
- 2012-12-19 JP JP2014547972A patent/JP6368247B2/ja active Active

Also Published As

Publication number	Publication date
EP2794964A1 (en)	2014-10-29
WO2013092701A1 (en)	2013-06-27
EP3042982A1 (en)	2016-07-13
EP2794964B1 (en)	2016-03-02
CN104302813A (zh)	2015-01-21
CN104302813B (zh)	2017-07-21
JP2015511988A (ja)	2015-04-23
RU2014121781A (ru)	2016-02-10

Legal Events

Date	Code	Title	Description
2015-12-09	A621	Written request for application examination	Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20151209
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2017-02-07	A601	Written request for extension of time	Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20170207
2017-06-01	A521	Request for written amendment filed	Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170601
2017-08-02	A131	Notification of reasons for refusal	Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20170802
2017-10-27	A601	Written request for extension of time	Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20171027
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2018-06-04	TRDD	Decision of grant or rejection written
2018-06-07	A01	Written decision to grant a patent or to grant a registration (utility model)	Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20180607
2018-07-12	A61	First payment of annual fees (during grant procedure)	Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20180706
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