JP6286367B2 - 経鼻配送装置 - Google Patents
経鼻配送装置 Download PDFInfo
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- JP6286367B2 JP6286367B2 JP2014558146A JP2014558146A JP6286367B2 JP 6286367 B2 JP6286367 B2 JP 6286367B2 JP 2014558146 A JP2014558146 A JP 2014558146A JP 2014558146 A JP2014558146 A JP 2014558146A JP 6286367 B2 JP6286367 B2 JP 6286367B2
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Description
Claims (26)
- 物質を患者の鼻腔に配送する経鼻配送装置であって、
ハウジングと、
前記患者の鼻腔にフィットするノーズピースと、
前記患者が使用中に呼息するマウスピースと、
前記マウスピースを前記ハウジングに連結するフレキシブル連結部と
を含み、
前記フレキシブル連結部は、前記ノーズピースに対して前記マウスピースが移動される際に、前記ノーズピースに対する前記マウスピースの移動が抑制されるよう構成された弾性要素であり、
前記マウスピースは、前記ノーズピースに対して非対称に移動され、
前記マウスピースの前記ノーズピースに対する移動は、前記ノーズピースに対する横方向よりも、前記ノーズピースの軸に対し平行な方向において大きくなるよう抑制される、経鼻配送装置。 - 前記ノーズピースが、物質が配送される出口と、使用中に前記患者の鼻孔に対し据え付けられ、前記ノーズピースと前記患者の鼻腔との間の密封フィットを達成する座部とを含む、
請求項1に記載の配送装置。 - 前記ノーズピースが、使用中に前記患者の鼻腔内に配置され、前記出口から外向きにテーパがかかった、テーパ部分を含む、
請求項2に記載の配送装置。 - 前記マウスピースの遠位端が、前記ノーズピースの軸に直交する方向よりも前記ノーズピースの軸に対し平行な方向に少なくとも1.5倍大きい距離を移動するように構成されている、
請求項1〜3のいずれかに記載の配送装置。 - 前記マウスピースの遠位端が、前記ノーズピースの軸に直交する方向よりも前記ノーズピースの軸に対し平行な方向に少なくとも1.75倍大きい距離を移動するように構成されている、
請求項1〜3のいずれかに記載の配送装置。 - 前記マウスピースの遠位端が、前記ノーズピースの軸に直交する方向よりも前記ノーズピースの軸に対し平行な方向に少なくとも2倍大きい距離を移動するように構成されている、
請求項1〜3のいずれかに記載の配送装置。 - 前記フレキシブル連結部が、一部分を前記ハウジングに取り付けられ、別の部分を前記マウスピースに取り付けられた環状連結部材を備え、前記マウスピースは、前記ハウジングに流体的に接続されている、
請求項1〜6のいずれかに記載の配送装置。 - 前記環状連結部材が、付勢力によって上方または下方に付勢されたときに、前記マウスピースがヒンジで動かされる、ヒンジ部分を規定する、
請求項7に記載の配送装置。 - 前記ヒンジ部分が、前記ノーズピースの近位の、前記環状連結部材の一方の側に設けられている、
請求項8に記載の配送装置。 - 前記環状連結部材は、前記マウスピースが前記環状連結部材の前記一方の側の周りでヒンジで動かされる、
請求項9に記載の配送装置。 - 前記環状連結部材が、前記環状連結部材の前記一方の側から前記ノーズピースの遠位の、前記環状連結部材の他方の側に向けて徐々に大きくなる弧状の湾曲した輪郭を有し、該弧状の湾曲した輪郭が、前記マウスピースが上向きに付勢されているときは伸長を提供し、前記マウスピースが下向きに付勢されているときは収縮を提供する、
請求項9または10に記載の配送装置。 - 前記湾曲した輪郭が、外向きに湾曲されており、
これにより、前記マウスピースを上向きに付勢するのに必要な付勢力が、前記マウスピースを下向きに付勢するのに必要な付勢力よりも小さい、
請求項11に記載の配送装置。 - 前記環状連結部材の前記湾曲した輪郭が傾斜材料で形成され、結果として前記環状連結部材の材料は、前記他方の側よりも前記一方の側で弾性が低い、
請求項11または12に記載の配送装置。 - 前記環状連結部材が傾斜材料で形成され、結果として前記環状連結部材の材料は、前記ノーズピースの遠位の、前記環状連結部材の他方の側よりも前記一方の側で弾性が低い、
請求項9または10に記載の配送装置。 - 前記環状連結部材が、前記マウスピースの軸を前記ノーズピースの軸に対し45度から55度の角度で提供するように構成されている、
請求項7〜14のいずれかに記載の配送装置。 - 前記環状連結部材が、前記マウスピースの軸を前記ノーズピースの軸に対し48度から52度の角度で提供するように構成されている、
請求項15に記載の配送装置。 - 前記環状連結部材が、前記マウスピースが前記ノーズピースの軸に対し7度から17度の角度で上向きに動かされることを可能にするように構成されている、
請求項15または16に記載の配送装置。 - 前記環状連結部材が、前記マウスピースが前記ノーズピースの軸に対し9度から15度の角度で上向きに動かされることを可能にするように構成されている、
請求項17に記載の配送装置。 - 前記環状連結部材が、前記マウスピースが前記ノーズピースの軸に対し10度から14度の角度で上向きに動かされることを可能にするように構成されている、
請求項18に記載の配送装置。 - 前記環状連結部材が、前記マウスピースが前記ノーズピースの軸に対し4度から10度の角度で下向きに動かされることを可能にするように構成されている、
請求項15〜19のいずれかに記載の配送装置。 - 前記環状連結部材が、前記マウスピースが前記ノーズピースの軸に対し5度から9度の角度で下向きに動かされることを可能にするように構成されている、
請求項20に記載の配送装置。 - 前記環状連結部材が、前記マウスピースが前記ノーズピースの軸に対し6度から8度の角度で下向きに動かされることを可能にするように構成されている、
請求項21に記載の配送装置。 - 前記環状連結部材が、熱可塑性エラストマー(TPE)で形成されている、
請求項7〜22のいずれかに記載の配送装置。 - 前記TPEがジュロメータ40から60を有する、
請求項23に記載の配送装置。 - 前記TPEがジュロメータ45から55を有する、
請求項24に記載の配送装置。 - 前記患者の鼻腔に物質を配送するために、手動で作動される物質供給ユニットをさらに備える、
請求項1〜25のいずれかに記載の配送装置。
Applications Claiming Priority (3)
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US201261603093P | 2012-02-24 | 2012-02-24 | |
US61/603,093 | 2012-02-24 | ||
PCT/EP2013/053747 WO2013124492A1 (en) | 2012-02-24 | 2013-02-25 | Nasal delivery devices |
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EP (1) | EP2817054B1 (ja) |
JP (1) | JP6286367B2 (ja) |
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ES (1) | ES2774159T3 (ja) |
HK (1) | HK1205699A1 (ja) |
IN (1) | IN2014DN07611A (ja) |
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MY (1) | MY170349A (ja) |
PL (1) | PL2817054T3 (ja) |
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CA2865353A1 (en) | 2013-08-29 |
KR20150003725A (ko) | 2015-01-09 |
IN2014DN07611A (ja) | 2015-05-15 |
AU2013223973A1 (en) | 2014-10-02 |
MX358061B (es) | 2018-08-03 |
ZA201406596B (en) | 2018-05-30 |
PL2817054T3 (pl) | 2020-12-14 |
MY170349A (en) | 2019-07-22 |
RU2014138495A (ru) | 2016-04-10 |
US20220152324A1 (en) | 2022-05-19 |
US10076614B2 (en) | 2018-09-18 |
WO2013124492A1 (en) | 2013-08-29 |
US20150013677A1 (en) | 2015-01-15 |
RU2644269C2 (ru) | 2018-02-08 |
CN104428026A (zh) | 2015-03-18 |
EP2817054B1 (en) | 2019-12-04 |
SG10201600049SA (en) | 2016-02-26 |
EP2817054A1 (en) | 2014-12-31 |
SG11201405179VA (en) | 2014-10-30 |
CN104428026B (zh) | 2018-08-14 |
DK2817054T3 (da) | 2020-03-02 |
JP2015507990A (ja) | 2015-03-16 |
HK1205699A1 (en) | 2016-02-19 |
ES2774159T3 (es) | 2020-07-17 |
MX2014010147A (es) | 2015-10-22 |
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