JP6080648B2 - 表面増強ラマン散乱ユニット - Google Patents
表面増強ラマン散乱ユニット Download PDFInfo
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- JP6080648B2 JP6080648B2 JP2013073312A JP2013073312A JP6080648B2 JP 6080648 B2 JP6080648 B2 JP 6080648B2 JP 2013073312 A JP2013073312 A JP 2013073312A JP 2013073312 A JP2013073312 A JP 2013073312A JP 6080648 B2 JP6080648 B2 JP 6080648B2
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- raman scattering
- enhanced raman
- handling substrate
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- 238000004416 surface enhanced Raman spectroscopy Methods 0.000 title claims description 102
- 239000000758 substrate Substances 0.000 claims description 91
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- 230000003287 optical effect Effects 0.000 claims description 36
- 239000011347 resin Substances 0.000 claims description 14
- 229920005989 resin Polymers 0.000 claims description 14
- 230000031700 light absorption Effects 0.000 claims 1
- 238000001069 Raman spectroscopy Methods 0.000 description 21
- 239000010410 layer Substances 0.000 description 17
- 230000006866 deterioration Effects 0.000 description 15
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- 239000004020 conductor Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
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- 229910052751 metal Inorganic materials 0.000 description 5
- 230000005284 excitation Effects 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 238000003860 storage Methods 0.000 description 4
- 239000012298 atmosphere Substances 0.000 description 3
- 238000002844 melting Methods 0.000 description 3
- 238000004611 spectroscopical analysis Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 229910001111 Fine metal Inorganic materials 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
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- 239000004593 Epoxy Substances 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
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- 125000004122 cyclic group Chemical group 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
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- 229910052737 gold Inorganic materials 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 229910000679 solder Inorganic materials 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
Landscapes
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Description
[第1実施形態]
[第2実施形態]
[第3実施形態]
[第4実施形態]
Claims (8)
- 一体的に形成されたハンドリング基板と、
前記ハンドリング基板の厚さ方向における一方の側に開口するように前記ハンドリング基板に設けられた収容空間内に固定された表面増強ラマン散乱素子と、を備え、
前記表面増強ラマン散乱素子は、
前記収容空間の内面上に配置された基板と、
前記基板上に形成され、表面増強ラマン散乱を生じさせる光学機能部と、を有し、
前記ハンドリング基板は、樹脂により一体的に形成されており、
前記樹脂は、光吸収色の樹脂である、表面増強ラマン散乱ユニット。 - 前記収容空間は、前記ハンドリング基板の前記一方の側の主面に設けられた凹部内の空間である、請求項1記載の表面増強ラマン散乱ユニット。
- 前記収容空間は、前記ハンドリング基板の前記一方の側の主面に一体的に形成された環状壁部の内側の空間である、請求項1記載の表面増強ラマン散乱ユニット。
- 前記収容空間の開口部を覆うように前記ハンドリング基板に配置されたカバーを更に備える、請求項1〜3のいずれか一項記載の表面増強ラマン散乱ユニット。
- 前記カバーは、光透過性を有する、請求項4記載の表面増強ラマン散乱ユニット。
- 前記カバーは、前記開口部に設けられた拡幅部内に配置され、前記厚さ方向に垂直な方向への移動が規制されている、請求項4又は5記載の表面増強ラマン散乱ユニット。
- 前記カバーは、前記厚さ方向から見た場合に前記開口部を包囲するように前記開口部の周囲に一体的に形成された突出部の内側に配置され、前記厚さ方向に垂直な方向への移動が規制されている、請求項4又は5記載の表面増強ラマン散乱ユニット。
- 前記表面増強ラマン散乱素子は、前記収容空間内に機械的に固定されている、請求項1〜7のいずれか一項記載の表面増強ラマン散乱ユニット。
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013073312A JP6080648B2 (ja) | 2013-03-29 | 2013-03-29 | 表面増強ラマン散乱ユニット |
CN201380042452.XA CN104520696B (zh) | 2012-08-10 | 2013-08-09 | 表面增强拉曼散射元件及其制造方法 |
PCT/JP2013/071707 WO2014025037A1 (ja) | 2012-08-10 | 2013-08-09 | 表面増強ラマン散乱素子及びその製造方法 |
EP22162962.9A EP4033222A1 (en) | 2012-08-10 | 2013-08-09 | Surface-enhanced raman scattering unit |
CN201380040609.5A CN104508465B (zh) | 2012-08-10 | 2013-08-09 | 表面增强拉曼散射单元 |
EP13828081.3A EP2884265A4 (en) | 2012-08-10 | 2013-08-09 | SURFACE-REINFORCED RAM SPREADING ELEMENT |
PCT/JP2013/071704 WO2014025035A1 (ja) | 2012-08-10 | 2013-08-09 | 表面増強ラマン散乱素子 |
US14/420,510 US9863884B2 (en) | 2012-08-10 | 2013-08-09 | Surface-enhanced Raman scattering element, and method for producing same |
EP13827643.1A EP2884264B1 (en) | 2012-08-10 | 2013-08-09 | Surface-enhanced raman scattering element, and method for producing same |
US14/420,502 US9863883B2 (en) | 2012-08-10 | 2013-08-09 | Surface-enhanced raman scattering element |
PCT/JP2013/071703 WO2014025034A1 (ja) | 2012-08-10 | 2013-08-09 | 表面増強ラマン散乱ユニット |
US14/420,483 US10551322B2 (en) | 2012-08-10 | 2013-08-09 | Surface-enhanced Raman scattering unit including integrally formed handling board |
CN201380040860.1A CN104508466B (zh) | 2012-08-10 | 2013-08-09 | 表面增强拉曼散射元件 |
EP13827352.9A EP2884262B1 (en) | 2012-08-10 | 2013-08-09 | Surface-enhanced raman scattering unit |
TW102128717A TWI604186B (zh) | 2012-08-10 | 2013-08-09 | Surface Enhanced Raman Scattering Element |
CN201811398924.6A CN109342395B (zh) | 2012-08-10 | 2013-08-09 | 表面增强拉曼散射单元 |
TW102128768A TWI583939B (zh) | 2012-08-10 | 2013-08-09 | Surface - enhanced Raman scattering unit |
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JP2013073312A JP6080648B2 (ja) | 2013-03-29 | 2013-03-29 | 表面増強ラマン散乱ユニット |
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JP2017005996A Division JP6282762B2 (ja) | 2017-01-17 | 2017-01-17 | 表面増強ラマン散乱ユニット |
Publications (3)
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JP2014196974A JP2014196974A (ja) | 2014-10-16 |
JP2014196974A5 JP2014196974A5 (ja) | 2016-06-30 |
JP6080648B2 true JP6080648B2 (ja) | 2017-02-15 |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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US9863883B2 (en) | 2012-08-10 | 2018-01-09 | Hamamatsu Photonics K.K. | Surface-enhanced raman scattering element |
US9863884B2 (en) | 2012-08-10 | 2018-01-09 | Hamamatsu Photonics K.K. | Surface-enhanced Raman scattering element, and method for producing same |
JP6230250B2 (ja) | 2013-03-29 | 2017-11-15 | 浜松ホトニクス株式会社 | 表面増強ラマン散乱ユニット、及びラマン分光分析方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
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CN100357738C (zh) * | 2004-03-26 | 2007-12-26 | 博奥生物有限公司 | 一种检测小分子化合物的方法 |
KR101168654B1 (ko) * | 2004-05-19 | 2012-07-25 | 브이피 호울딩 엘엘씨 | 표면 증강 라만 산란에 의한 화학기의 증강된 검출을 위한 층상의 플라즈몬 구조를 가진 광센서 |
JP2005337771A (ja) * | 2004-05-25 | 2005-12-08 | National Institute For Materials Science | ナノ構造を有する集積化ピラー構造光学素子 |
BRPI0719825A2 (pt) * | 2006-10-12 | 2014-05-06 | Koninkl Philips Electronics Nv | Sistema de detecção e método para detectar pelo menos uma molécula alvo |
JP4980324B2 (ja) * | 2008-09-30 | 2012-07-18 | テルモ株式会社 | 成分測定装置 |
EP2352010B1 (en) * | 2008-10-30 | 2016-01-13 | Nippon Telegraph And Telephone Corporation | Measuring chip installation/removal device, spr measurement system, and measuring chip installation/removal method |
WO2011022093A2 (en) * | 2009-04-13 | 2011-02-24 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and devices for detecting the presence of an analyte in a sample |
US20110166045A1 (en) * | 2009-12-01 | 2011-07-07 | Anuj Dhawan | Wafer scale plasmonics-active metallic nanostructures and methods of fabricating same |
US8509868B2 (en) * | 2011-04-12 | 2013-08-13 | Panasonic Corporation | Method for measuring a concentration of a biogenic substance contained in a living body |
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