JP5992330B2 - 物質を投与するための子宮内電子カプセル - Google Patents
物質を投与するための子宮内電子カプセル Download PDFInfo
- Publication number
- JP5992330B2 JP5992330B2 JP2012531527A JP2012531527A JP5992330B2 JP 5992330 B2 JP5992330 B2 JP 5992330B2 JP 2012531527 A JP2012531527 A JP 2012531527A JP 2012531527 A JP2012531527 A JP 2012531527A JP 5992330 B2 JP5992330 B2 JP 5992330B2
- Authority
- JP
- Japan
- Prior art keywords
- capsule
- electronic capsule
- electronic
- substance
- dispensing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/42—Gynaecological or obstetrical instruments or methods
- A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
- A61B17/43—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for artificial insemination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
- A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
- A61B5/4318—Evaluation of the lower reproductive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6861—Capsules, e.g. for swallowing or implanting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Pregnancy & Childbirth (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Description
Capsule and In Vivo Drug Delivery or Diagnostic System」という名称の国際公開WO2008/062333A2内により詳細に記載されており、その全文をここに参照として援用する。
Claims (18)
- 雌生殖器官内での配置のためにカプセルとして構成されるハウジングと、
前記雌生殖器官内から効果的に投与される物質を収容する前記ハウジング内の貯槽と、
前記物質を前記貯槽から前記ハウジングの開口を通じて前記雌生殖器官内に供給するよう前記貯槽の外側に圧力を加えるために前記ハウジング内に配置されるアクチュエータと、
前記物質に対して封止され且つ前記貯槽から前記雌生殖器官内への前記物質の供給のタイミングを制御するためのプログラムを含む前記ハウジング内の電子機器区画と、
前記ハウジングを支持するための支持体とを含み、
該支持体は、前記ハウジングよりも大きく、前記カプセルとして構成される前記ハウジングは、前記支持体内に配置され、前記支持体は、前記雌生殖器官からの前記カプセルの排出を抑止するよう構成される、
電子カプセル。 - ホルモンのレベルを測定するバイオセンサを更に含み、前記測定されるレベルに基づき前記計量分配を行うために更に構成される、請求項1に記載の電子カプセル。
- 前記測定は、エストラジオール、黄体形成ホルモン、及び、卵胞刺激ホルモンの1つ又はそれよりも多くのためである、請求項2に記載の電子カプセル。
- 前記雌生殖器官が子宮であるよう構成される、請求項1に記載の電子カプセル。
- 紐が当該電子カプセルから子宮頚部内に延びる、請求項4に記載の電子カプセル。
- 前記雌生殖器官が子宮頚部であるよう構成される、請求項1に記載の電子カプセル。
- 前記計量分配は、当該電子カプセルのホストの生殖周期と合わせられる、請求項1に記載の電子カプセル。
- pHセンサを含み、前記計量分配が前記pHセンサの出力に応答するよう構成される、請求項1に記載の電子カプセル。
- 前記物質が***を運ぶ流体を含むよう構成される、請求項1に記載の電子カプセル。
- 周囲環境から、効果的な投与のための時間を感知するために、並びに、前記時間での前記物質の前記計量分配のために構成される、請求項9に記載の電子カプセル。
- 前記物質がプロゲステロンを含むよう構成される、請求項1に記載の電子カプセル。
- 前記物質が医薬を含むよう構成される、請求項1に記載の電子カプセル。
- 当該カプセルは、子宮腺筋症を管理するためにホルモンレベルを管理するために前記計量分配することのために更に構成される、請求項1に記載の電子カプセル。
- 前記貯槽の計量分配孔が取り外し可能なオイルの栓を有する、請求項1に記載の電子カプセル。
- 摩擦を減少するために横方向板の上に支持されるネジ山付きシャフトを有するモータを含む、請求項1に記載の電子カプセル。
- 圧力均衡のために、当該カプセルの周囲環境への孔を備えるモータ区画を含む、請求項1に記載の電子カプセル。
- 請求項1乃至16に記載の電子カプセルを作動するコンピュータソフトウェア製品であって、
当該コンピュータソフトウェア製品は、複数の行為を遂行するためにプロセッサによって実行可能な命令を含むコンピュータプログラムを具現するコンピュータ読取り可能な記憶媒体を含み、
前記複数の行為は、前記電子カプセルが前記雌生殖器官内に配置されている間に、前記貯槽から、前記雌生殖器官内から効果的に投与される物質を計量分配する行為を含む、
コンピュータソフトウェア製品。 - 前記支持体(154)は、時間の経過と共に腐食し或いは低剛性になる材料で作製される、請求項1に記載の電子カプセル。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24680209P | 2009-09-29 | 2009-09-29 | |
US61/246,802 | 2009-09-29 | ||
PCT/IB2010/054269 WO2011039680A1 (en) | 2009-09-29 | 2010-09-21 | Intrauterine electronic capsule for administering a substance |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013505804A JP2013505804A (ja) | 2013-02-21 |
JP5992330B2 true JP5992330B2 (ja) | 2016-09-14 |
Family
ID=43430680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012531527A Expired - Fee Related JP5992330B2 (ja) | 2009-09-29 | 2010-09-21 | 物質を投与するための子宮内電子カプセル |
Country Status (5)
Country | Link |
---|---|
US (1) | US20130066302A1 (ja) |
EP (1) | EP2482914A1 (ja) |
JP (1) | JP5992330B2 (ja) |
CN (1) | CN103079632A (ja) |
WO (1) | WO2011039680A1 (ja) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI477276B (zh) | 2008-04-28 | 2015-03-21 | Repros Therapeutics Inc | 抗黃體素給藥方案 |
NZ702467A (en) * | 2012-05-31 | 2016-07-29 | Repros Therapeutics Inc | Formulations and methods for vaginal delivery of antiprogestins |
ES2688821T3 (es) | 2012-11-02 | 2018-11-07 | Repros Therapeutics Inc. | Métodos y composiciones para tratar afecciones dependientes de la progesterona |
US20160022198A1 (en) * | 2013-03-08 | 2016-01-28 | Li Galli B.V. | Vaginal Drug Delivery and/or Diagnostic System |
US9801660B2 (en) * | 2014-07-31 | 2017-10-31 | Palo Alto Research Center Incorporated | Implantable fluid delivery devices, systems, and methods |
EP3250183A1 (en) * | 2015-01-30 | 2017-12-06 | Li Galli B.V. | Vaginal drug delivery device |
EP3153137A1 (en) * | 2015-10-06 | 2017-04-12 | Li Galli B.V. | Vaginal drug delivery device and vaginal diagnostic device |
US10939865B2 (en) | 2015-10-06 | 2021-03-09 | Ligalli B.V. | Vaginal drug delivery device and vaginal diagnostic device |
CN105997333A (zh) * | 2016-05-11 | 2016-10-12 | 江苏雷奥生物科技有限公司 | 一种新型优生优育器械 |
MX2018014362A (es) * | 2016-05-25 | 2019-07-10 | Kuster Martin | Dispositivo intrauterino mejorado. |
CA3054004A1 (en) * | 2017-03-07 | 2018-09-13 | University Of Southampton | Intra-uterine monitoring system |
US20220379022A1 (en) * | 2019-10-30 | 2022-12-01 | Thermalin, Inc. | Agent delivery systems, devices, and methods |
CN111631686B (zh) * | 2020-05-18 | 2022-03-15 | 湖南大学 | 一种利用核磁共振成像监测胃酸pH值的胶囊及其制备方法 |
CN112472975B (zh) * | 2020-11-19 | 2022-04-12 | 华中科技大学 | 一种宫内药物控释*** |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4102998A (en) * | 1972-10-02 | 1978-07-25 | Morton Gutnick | Process for the prevention of venereal disease |
US3923060A (en) * | 1974-04-23 | 1975-12-02 | Jr Everett H Ellinwood | Apparatus and method for implanted self-powered medication dispensing having timing and evaluator means |
US4900303A (en) * | 1978-03-10 | 1990-02-13 | Lemelson Jerome H | Dispensing catheter and method |
US4578076A (en) * | 1984-03-20 | 1986-03-25 | The Population Council, Inc. | Medicated intracervical and intrauterine devices |
JP2812887B2 (ja) * | 1995-02-06 | 1998-10-22 | 嶺田 恒 | 不妊治療用防疫人工授精カプセル |
JP2001520999A (ja) * | 1997-10-28 | 2001-11-06 | アシビ, エルエルシー | 女性の性的機能不全の処置 |
IL144948A0 (en) * | 1999-02-18 | 2002-06-30 | Biovalve Technologies Inc | Electroactive pore |
US7160258B2 (en) * | 2001-06-26 | 2007-01-09 | Entrack, Inc. | Capsule and method for treating or diagnosing the intestinal tract |
US7044911B2 (en) * | 2001-06-29 | 2006-05-16 | Philometron, Inc. | Gateway platform for biological monitoring and delivery of therapeutic compounds |
US8257244B2 (en) * | 2001-08-01 | 2012-09-04 | Anecova Sa | Intrauterine device, method of making such a device and method for putting active elements within the uterine cavity |
JP2005185567A (ja) * | 2003-12-25 | 2005-07-14 | Olympus Corp | 医療用カプセル装置 |
EP2035075A1 (en) | 2006-06-20 | 2009-03-18 | Koninklijke Philips Electronics N.V. | Electronic capsule for treating gastrointestinal disease |
JP5697871B2 (ja) * | 2006-11-21 | 2015-04-08 | メディメトリクス ペルソナリズド ドルグ デリヴェリー ベー ヴェ | 薬物送達カプセル、及び生体内での薬剤送達又は診断システム |
EP2057972A1 (en) * | 2007-11-07 | 2009-05-13 | N.V. Organon | Intrauterine deposit |
US9333329B2 (en) * | 2008-03-04 | 2016-05-10 | Elan Ziv | Vaginal carrier for the controlled release of substances |
PL2381932T3 (pl) * | 2009-01-29 | 2019-01-31 | Fondazione Irccs Istituto Nazionale Dei Tumori | Urządzenie wewnątrzszyjkowe do uwalniania leków w miejscowo- regionalnym leczeniu nowotworu szyjki macicy |
US8568374B2 (en) * | 2009-05-04 | 2013-10-29 | Merck Sharp & Dohme B.V. | Intrauterine system |
-
2010
- 2010-09-21 EP EP10779040A patent/EP2482914A1/en not_active Withdrawn
- 2010-09-21 US US13/498,835 patent/US20130066302A1/en not_active Abandoned
- 2010-09-21 CN CN2010800490443A patent/CN103079632A/zh active Pending
- 2010-09-21 WO PCT/IB2010/054269 patent/WO2011039680A1/en active Application Filing
- 2010-09-21 JP JP2012531527A patent/JP5992330B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN103079632A (zh) | 2013-05-01 |
WO2011039680A1 (en) | 2011-04-07 |
JP2013505804A (ja) | 2013-02-21 |
EP2482914A1 (en) | 2012-08-08 |
US20130066302A1 (en) | 2013-03-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5992330B2 (ja) | 物質を投与するための子宮内電子カプセル | |
JP7078345B2 (ja) | 膣内薬剤送達および/または膣内診断を行なうシステム | |
US7811279B2 (en) | Programmable medical drug delivery systems and methods for delivery of multiple fluids and concentrations | |
Liao et al. | Normal labor: mechanism and duration | |
JP2019528103A (ja) | 骨盤底筋をトレーニングするためのデバイス、システムおよび方法 | |
AU2006239700A1 (en) | A remote controlled tubular implant device and implanting apparatus | |
US20130345505A1 (en) | Electronically And Remotely Controlled Pill And System For Delivering At Least One Medicament | |
US20180015270A1 (en) | Vaginal Drug Delivery Device | |
US20080171950A1 (en) | Systems and methods for a pregnancy monitoring device | |
Tiboni | Aromatase inhibitors and teratogenesis | |
EP3700477A1 (en) | Devices, systems, and methods for training pelvic floor muscles | |
US6468223B2 (en) | Method and apparatus for predicting and detecting ovulation | |
Richter et al. | Contractile reactivity of human myometrium in isolated non-pregnant uteri | |
US20230149146A1 (en) | An automated controlled release device for livestock management and methods of use thereof | |
Sun et al. | Doppler US Nutrient Artery Waveform Change in Assessment of Non-pregnant Uterus Response to Oxytocin | |
Manikandan | Microchip: New Era in Novel Drug Delivery Systems-A Review | |
Boland et al. | Ultrasound and in vitro fertilization: Pictorial Review With Case Study | |
JPH11299903A (ja) | 体内埋込型薬液投与装置 | |
KR20040064353A (ko) | 실시간 체액 검사와 이에 따른 약물투여를 하는 부착형의료 장비 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130625 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20130628 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20130924 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20131001 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20131125 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20140507 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20140807 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20140814 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140904 |
|
A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20150130 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20150317 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150716 |
|
A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20150727 |
|
A912 | Re-examination (zenchi) completed and case transferred to appeal board |
Free format text: JAPANESE INTERMEDIATE CODE: A912 Effective date: 20150925 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20160817 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5992330 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |