JP5967756B2 - 分光用基板 - Google Patents
分光用基板 Download PDFInfo
- Publication number
- JP5967756B2 JP5967756B2 JP2012103029A JP2012103029A JP5967756B2 JP 5967756 B2 JP5967756 B2 JP 5967756B2 JP 2012103029 A JP2012103029 A JP 2012103029A JP 2012103029 A JP2012103029 A JP 2012103029A JP 5967756 B2 JP5967756 B2 JP 5967756B2
- Authority
- JP
- Japan
- Prior art keywords
- substrate
- fine particles
- region
- metal layer
- metal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Description
(実施例1)
図2は、分光用基板の具体的な作製方法を示す。まず、基板としてガラス基板11を用い、ガラス基板11の上に微粒子としてシリカナノ粒子12を吸着させる。このために、ガラス基板11表面の化学修飾を行う。アミノプロピルトリメトキシシランもしくはアミノプロピルトリエトキシシラン等のシランカップリング試薬の水溶液を重量比で0.1%〜10%のものを用意し、ガラス基板11を水溶液中に10秒から1分の間浸漬する。
次に、被検体及び溶媒が油性物質の場合の分光用基板の作製例を以下に示す。水と油とは混ざらない性質があるので、分光測定領域となる表面増強領域を疎水性、表面増強領域以外の周辺の領域を親水性にすることで、油性サンプルを滴下すると、サンプルは球状の液滴を形成する。
2 微粒子
3 金属層
4 金属層
10 金属付着微粒子
13 シラン分子
14 シラン分子
15 チオール分子
Claims (4)
- 基板上に吸着された疎水性又は親水性を有する微粒子群と、分光測定領域のみ前記各微粒子の表面に形成された表面増強用の第1の金属層とを備え、前記分光測定領域以外の前記基板表面には前記疎水性又は親水性を有する微粒子が配置されていることを特徴とする分光用基板。
- 前記疎水性又は親水性を有する微粒子は、シランカップリング処理が施されていることを特徴とする請求項1に記載の分光用基板。
- 前記微粒子群の各微粒子は、粒径5nm〜1000nmのシリカ、酸化チタン、ポリスチレンのいずれかの材料で構成されていることを特徴とする請求項1又は請求項2に記載の分光用基板。
- 前記第1の金属層は、膜厚5nm〜1000nmの銀あるいは金で構成されていることを特徴とする請求項1〜請求項3のいずれか1項に記載の分光用基板。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012103029A JP5967756B2 (ja) | 2012-04-27 | 2012-04-27 | 分光用基板 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012103029A JP5967756B2 (ja) | 2012-04-27 | 2012-04-27 | 分光用基板 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013231641A JP2013231641A (ja) | 2013-11-14 |
JP5967756B2 true JP5967756B2 (ja) | 2016-08-10 |
Family
ID=49678209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012103029A Expired - Fee Related JP5967756B2 (ja) | 2012-04-27 | 2012-04-27 | 分光用基板 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP5967756B2 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016031140A1 (ja) * | 2014-08-27 | 2016-03-03 | 富士フイルム株式会社 | 光電場増強デバイス |
CN105424677B (zh) * | 2015-12-02 | 2018-01-12 | 公安部上海消防研究所 | 基于表面增强拉曼光谱检测火灾现场残留有机物的方法 |
CN105499602B (zh) * | 2015-12-21 | 2018-11-16 | 上海交通大学 | 一种基于还原法合成金纳米颗粒的sers基底制备方法 |
KR20180132703A (ko) | 2016-03-31 | 2018-12-12 | 세키스이가세이힝코교가부시키가이샤 | 금속 피복 이형 수지 입자와 그 제조 방법, 금속 피복 이형 수지 입자의 배열막과 그 제조 방법, 입자군, 및 입자 배열막의 제조 방법 |
CN109856116B (zh) * | 2019-02-28 | 2021-06-29 | 吉林大学 | 一种利用表面增强拉曼散射原位监测化学反应的分级纳米锥阵列及其制备方法 |
KR102274582B1 (ko) * | 2019-12-27 | 2021-07-08 | (주)광림정공 | 국부적 친수성을 지닌 표면증강 라만산란기판 및 그 제조방법 |
WO2022123968A1 (ja) * | 2020-12-07 | 2022-06-16 | 株式会社堀場製作所 | ラマン分析用プレート、ラマン分析装置、分析システム、及びラマン分析方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003042947A (ja) * | 2001-07-31 | 2003-02-13 | Mitsubishi Chemicals Corp | 表面プラズモン共鳴セル及びそれを利用した試料流体の分析方法 |
JP2005144569A (ja) * | 2003-11-12 | 2005-06-09 | Hitachi Ltd | 二次元配列構造体基板および該基板から剥離した微粒子 |
JP4418705B2 (ja) * | 2004-04-27 | 2010-02-24 | 富士フイルム株式会社 | バイオセンサー |
JP2006047153A (ja) * | 2004-08-05 | 2006-02-16 | Sony Corp | Dnaチップの製造方法と製造システム、ハイブリダイゼーション検出方法と検出システム、並びに基板処理装置と基板処理方法 |
EP1715326A1 (en) * | 2005-04-22 | 2006-10-25 | Universität Heidelberg | Sensor chip with connected non-metallic particles comprising a metallic coating |
JP5500571B2 (ja) * | 2009-03-26 | 2014-05-21 | 株式会社ニデック | 試験片,該試験片の製造方法 |
JP5494954B2 (ja) * | 2010-03-29 | 2014-05-21 | 学校法人 東洋大学 | 分析用基板及びその製造方法 |
-
2012
- 2012-04-27 JP JP2012103029A patent/JP5967756B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2013231641A (ja) | 2013-11-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5967756B2 (ja) | 分光用基板 | |
Yap et al. | Nanoparticle cluster arrays for high-performance SERS through directed self-assembly on flat substrates and on optical fibers | |
Wang et al. | Flexible, transparent and highly sensitive SERS substrates with cross-nanoporous structures for fast on-site detection | |
US9360429B2 (en) | SERS substrates | |
Smith | Practical understanding and use of surface enhanced Raman scattering/surface enhanced resonance Raman scattering in chemical and biological analysis | |
Miao et al. | High-sensitivity nanophotonic sensors with passive trapping of analyte molecules in hot spots | |
US10241110B2 (en) | Plasmonic biosensors with built-in artificial antibodies | |
Wu et al. | Ultrasensitive and simultaneous detection of multielements in aqueous samples based on biomimetic array combined with laser-induced breakdown spectroscopy | |
JP6954152B2 (ja) | 分析用基板 | |
Zhu et al. | Surface-enhanced Raman scattering of 4-mercaptobenzoic acid and hemoglobin adsorbed on self-assembled Ag monolayer films with different shapes | |
Nistico et al. | New branched flower-like Ag nanostructures for SERS analysis | |
Liu et al. | Silica nanowire assemblies as three-dimensional, optically transparent platforms for constructing highly active SERS substrates | |
WO2013185167A1 (en) | Metallic nanoparticle treated cellulosic substrate as a sers biodiagnostic platform | |
Mhlanga et al. | Fabrication of surface enhanced Raman spectroscopy substrates on solid supports | |
TW202043742A (zh) | 一種高增益表面拉曼散射裝置及其製造方法 | |
Xu et al. | Multiscale structure enabled effective plasmon coupling and molecular enriching for SERS detection | |
Lee et al. | Hierarchical nanoflowers on nanograss structure for a non-wettable surface and a SERS substrate | |
KR20180059739A (ko) | 라만분광기반 바이오센서의 제조방법 | |
Mao et al. | Detection of trace Rhodamine B using stable, uniformity, and reusable SERS substrate based on Ag@ SiO2-Au nanoparticles | |
Han et al. | Recyclable SERS monitoring of food quality based on the shrubby morphology of titania oxide-triggered electromagnetic “hotspots” | |
Dong et al. | Capillary-force-assisted self-assembly of gold nanoparticles into highly ordered plasmonic thin films for ultrasensitive SERS | |
KR102202509B1 (ko) | 소수성 페이퍼 기판 기반의 표면증강 라만산란 센서 및 그 제작 방법 | |
CN111965156B (zh) | 一种高增益表面拉曼散射装置及其制造方法 | |
Rutherford et al. | Photochemical growth of highly densely packed gold nanoparticle films for biomedical diagnostics | |
KR101613779B1 (ko) | 그래핀 산화물로 기능화된 플라즈모닉 탐침체를 가지는 국부적 표면 플라즈몬 공명(lspr) 센서와 그 제조 방법 및 해당 센서를 이용한 방향족 휘발성 유기 화합물 검출 방법 및 장치 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20150401 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20160120 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20160202 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20160401 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20160621 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20160701 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5967756 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |