JP5916631B2 - 薬用モジュール用の可撓性リザーバ - Google Patents
薬用モジュール用の可撓性リザーバ Download PDFInfo
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- JP5916631B2 JP5916631B2 JP2012551593A JP2012551593A JP5916631B2 JP 5916631 B2 JP5916631 B2 JP 5916631B2 JP 2012551593 A JP2012551593 A JP 2012551593A JP 2012551593 A JP2012551593 A JP 2012551593A JP 5916631 B2 JP5916631 B2 JP 5916631B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
- A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2422—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
- A61M5/2425—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/281—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
- A61M5/282—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3294—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3295—Multiple needle devices, e.g. a plurality of needles arranged coaxially or in parallel
- A61M5/3297—Needles arranged coaxially
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/347—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub rotatable, e.g. bayonet or screw
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Environmental & Geological Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
一度、モジュールが使用され取り外されたら、1番目の薬物送達デバイスへの薬用モジュールの再取り付けの物理的阻止。
一度、それが使用されたら、薬物投与インターフェイスを通した以後の液体流の物理的/水圧的阻止。
1番目の薬物送達デバイスの用量セッター及び/又は用量ボタンの物理的ロック。
視覚的警告(一度、挿入及び/又は流体流が生じたら、モジュールに関する指示窓内の例えば色及び/又は匂い及び/又は警告文章/表示物(indicia)の変化)。
触覚フィードバック(使用後のモジュールハブの外面における触覚特性の有無)。
1 セプタム
2 第2の薬剤
3 針
4 薬用モジュール
5 係合ニードル
7 薬物送達デバイス
8 取り付け手段
9 連結手段
10 ハウジング
11 ばね
12 用量セッター
13 用量ボタン
14 一次リザーバ/カートリッジ
15 スリーブ
17 ショルダ
18 締まり嵌め
21 バイパスチャンネル
22 ニードルガード
23 オープントップ
28 逆止弁
29 キャップ
30 内部チャンバ
31 可撓性リザーバ/カプセル
32 遠位端
40 突出部
41 突出部
42 突出部
43 可撓性ハウジング
44 バイパススリット弁
45 スリット弁
50 突出部
Claims (16)
- 第一の薬剤の一次リザーバ(14)を含む薬物送達デバイス(7)に取り付け可能な、第二の薬剤(2)を含む薬用モジュール(4)であって、
該薬用モジュール(4)は、
遠位のニードルカニューレ(3)の遠位端は注射部位に適用され、近位のニードルカニューレ(5)の近位端は一次リザーバ(14)を穿孔するように構成されている、近位のニードルカニューレ(5)と遠位のニードルカニューレ(3)、
遠位ニードルカニューレ(3)を保護するように適合され配置され、注射部位に適用中に軸方向に動くように構成されているニードルガード(22)、
ハウジング(43)の遠位端の可撓性セクション内に位置する遠位弁(45)を含み、
遠位のニードルカニューレ(3)と近位のニードルカニューレ(5)の間の軸方向にリザーバ(31)が配置され、遠位のニードルカニューレ(3)と近位のニードルカニューレ(5)は、ニードルガード(22)が近位方向に動くとき、リザーバ(31)と流体連通するように構成されており、
リザーバ(31)は、少なくとも1つの可撓性セクションを含むハウジング(43)を含み、該ハウジング(43)は近位端、遠位端を有し、該第二の薬剤(2)を保持する内部チャンバ(30)を画成し、
ニードルガード(22)が近位方向に動くと、遠位弁(45)はニードルガード(22)と少なくとも1つの可撓性セクションとの機械的協動により開き、内部チャンバ(30)から第二の薬剤(2)が流出し、遠位ニードルカニューレ(3)から排出することを可能とする、
上記薬用モジュール(4)。 - ハウジング(43)が医療グレードのシリコン又は熱可塑性エラストマーを含む、請求項1に記載の薬用モジュール(4)。
- 遠位弁(45)がスリット弁である、請求項1又は2に記載の薬用モジュール(4)。
- ハウジング(43)がバイパスチャンネル(21)を含み、ここでバイパスチャンネル(21)は近位端を遠位端に連結し、内部チャンバ(30)と流体連通していない、請求
項1〜3のいずれか1項に記載の薬用モジュール(4)。 - バイパスチャンネル(21)が少なくとも1つのスリット弁(44)を含む、請求項4に記載の薬用モジュール(4)。
- 薬用モジュール(4)が薬物送達デバイス(7)に取り付けられたとき、バイパスチャンネル(21)が一次リザーバ(14)からの第一の薬剤の流体流に対して解放される、請求項5に記載の薬用モジュール。
- バイパスチャンネル(21)のスリット弁(44)がハウジング(43)の前記可撓性セクションに又は更なる可撓性セクションに位置する、請求項5に記載の薬用モジュール(4)。
- ハウジング(43)が、突出部(42)を含み、該突出部は、遠位弁(45)に作動的に連結され、その突出部(42)とニードルガード(22)との機械的協動により遠位弁(45)の開口を可能にするように構成されている、請求項1〜7のいずれか1項に記載の
薬用モジュール(4)。 - 剛性の末端キャップ(29)がハウジング(43)の近位端に位置し、好ましくは、末端キャップ(29)は、内部チャンバ(30)と流体連通を可能にするように適合され配置される逆止弁(28)を含む、請求項1〜8のいずれか1項に記載の薬用モジュール(4)。
- 薬物送達デバイス(7)への取り付けのために構成される第2のハウジング(10)を含み、ニードルガード(22)は第2のハウジング(10)と作動的に連結している、請求項5〜7のいずれか1項に記載の薬用モジュール。
- ハウジング(43)及びニードルガード(22)の機械的協動がリザーバ(31)のバイパスチャンネル(21)のスリット弁(44)及び遠位弁(45)の開口を可能にする、請求項10に記載の薬用モジュール(4)。
- ハウジング(43)が少なくとも2つの突出部(41、42)を含み、各突出部(41、42)はバイパスチャンネル(21)のスリット弁(44)及び遠位弁(45)の1つに作動的に連結され、そしてそれぞれの突出部(41、42)は、ニードルガード(22)が2つの異なる軸方向位置にある場合にニードルガード(22)に係合するように構成される、請求項10又は11に記載の薬用モジュール(4)。
- 請求項10〜12のいずれか1項に記載の薬用モジュール(4)及び一次リザーバ(14)含んでなり、一次リザーバ(14)が第1の薬剤の少なくとも1つの用量を保持している、薬物送達デバイス(7)。
- ハウジング(43)は、薬用モジュール(4)が薬物送達デバイス(7)に連結されたとき、ニードルガード(22)と機械的協動をするように構成され、そしてニードルガード(22)は、バイパスチャンネル(21)のスリット弁(44)が開くように遠位方向に伸びる、請求項13に記載の薬物送達デバイス(7)。
- ハウジング(43)は、ハウジング(43)の遠位弁(45)が開き、そして一次リザーバ(14)及び薬用モジュール(4)のリザーバ(31)の流体連通が可能にされるように、ニードルガード(22)が近位方向に後退したとき、ニードルガード(22)と機
械的協働をするように構成される、請求項13又は14に記載の薬物送達デバイス(7)。 - 薬物送達デバイス(7)の遠位端(32)は第一の連結手段(9)を有し、薬用モジュール(4)はハウジング(10)の近位端に第二の連結手段(8)を有する、請求項13〜15のいずれか1項に記載の薬物送達デバイス(7)。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30170310P | 2010-02-05 | 2010-02-05 | |
US61/301,703 | 2010-02-05 | ||
EP10160836 | 2010-04-23 | ||
EP10160836.2 | 2010-04-23 | ||
PCT/EP2011/051393 WO2011095478A1 (en) | 2010-02-05 | 2011-02-01 | Flexible reservoir for a medicated module |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013518638A JP2013518638A (ja) | 2013-05-23 |
JP5916631B2 true JP5916631B2 (ja) | 2016-05-11 |
Family
ID=42768096
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012551593A Expired - Fee Related JP5916631B2 (ja) | 2010-02-05 | 2011-02-01 | 薬用モジュール用の可撓性リザーバ |
Country Status (9)
Country | Link |
---|---|
US (1) | US9358342B2 (ja) |
EP (1) | EP2531235A1 (ja) |
JP (1) | JP5916631B2 (ja) |
CN (1) | CN102753223B (ja) |
AU (1) | AU2011212556B2 (ja) |
BR (1) | BR112012019549A2 (ja) |
CA (1) | CA2788647A1 (ja) |
IL (1) | IL221140A (ja) |
WO (1) | WO2011095478A1 (ja) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003068290A2 (en) | 2002-02-11 | 2003-08-21 | Antares Pharma, Inc. | Intradermal injector |
BRPI0614025A2 (pt) | 2005-01-24 | 2012-12-25 | Antares Pharma Inc | injetores de jato |
US8251947B2 (en) | 2006-05-03 | 2012-08-28 | Antares Pharma, Inc. | Two-stage reconstituting injector |
US9144648B2 (en) | 2006-05-03 | 2015-09-29 | Antares Pharma, Inc. | Injector with adjustable dosing |
WO2009114542A1 (en) | 2008-03-10 | 2009-09-17 | Antares Pharma, Inc. | Injector safety device |
ES2738539T3 (es) | 2008-08-05 | 2020-01-23 | Antares Pharma Inc | Inyector de dosis múltiples |
AU2010226442A1 (en) | 2009-03-20 | 2011-10-13 | Antares Pharma, Inc. | Hazardous agent injection system |
JP2014514100A (ja) * | 2011-04-21 | 2014-06-19 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ロック機能を備えた薬用モジュール |
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2011
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- 2011-02-01 CN CN201180008509.5A patent/CN102753223B/zh not_active Expired - Fee Related
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- 2011-02-01 AU AU2011212556A patent/AU2011212556B2/en not_active Ceased
- 2011-02-01 EP EP11701523A patent/EP2531235A1/en not_active Withdrawn
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CN102753223A (zh) | 2012-10-24 |
AU2011212556B2 (en) | 2015-02-19 |
BR112012019549A2 (pt) | 2018-03-27 |
EP2531235A1 (en) | 2012-12-12 |
US9358342B2 (en) | 2016-06-07 |
AU2011212556A1 (en) | 2012-08-16 |
WO2011095478A1 (en) | 2011-08-11 |
IL221140A (en) | 2015-07-30 |
US20130018323A1 (en) | 2013-01-17 |
CN102753223B (zh) | 2015-06-24 |
IL221140A0 (en) | 2012-09-24 |
CA2788647A1 (en) | 2011-08-11 |
JP2013518638A (ja) | 2013-05-23 |
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