JP5719497B2 - 飼料添加剤、飼料、その製造方法、斃死予防剤、及び飼育方法 - Google Patents
飼料添加剤、飼料、その製造方法、斃死予防剤、及び飼育方法 Download PDFInfo
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- JP5719497B2 JP5719497B2 JP2008085057A JP2008085057A JP5719497B2 JP 5719497 B2 JP5719497 B2 JP 5719497B2 JP 2008085057 A JP2008085057 A JP 2008085057A JP 2008085057 A JP2008085057 A JP 2008085057A JP 5719497 B2 JP5719497 B2 JP 5719497B2
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Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
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- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
Description
試験方法:平均体重26gのカワハギを20,000尾ずつ本発明区と対照区に分養し、海面生簀にて約3ヶ月間飼育した。この期間の水温は28.5〜18.3℃であった。発明区には、実施例1で製造した小麦発酵抽出物とバチルス菌体入り混合飼料を、小麦発酵抽出物を1日あたり20〜40μg/魚体重1kgの量で、バチルス菌体を1日あたり0.01mg〜1mg/魚体重1kgの量で、投与間隔を4日投与4日休みとして投与した。なお、休みの期間は対照区と同じ小麦発酵抽出物とバチルス菌体を添加しない混合飼料を投与した。その後、試験期間中の死亡数を計測して生残率を求めた。
試験方法:平均体重42gのマダイを16,500尾ずつ本発明区と対照区に分養し、海面生簀にて約3ヶ月間飼育した。発明区には、実施例1で製造した小麦発酵抽出物とバチルス菌体入り混合飼料を、小麦発酵抽出物を1日あたり20μg/魚体重1kgの量で、バチルス菌体を1日あたり0.01mg〜1mg/魚体重1kgの量で、投与間隔を4日投与4日休みとして投与した。なお、休みの期間は対照区と同じ小麦発酵抽出物とバチルス菌体を添加しない混合飼料を投与した。その後、試験期間中の死亡数を計測して生残率を求めた。
試験方法:ブリを約5,000尾ずつ3群(1〜3区)に分け、海面生簀にて2ヶ月間飼育した。本発明の1区は実施例1で製造した小麦発酵抽出物とバチルス菌体入り混合飼料を、小麦発酵抽出物を1日あたり20μg/魚体重1kgの量で、バチルス菌体を1日あたり0.01mg〜1mg/魚体重1kgの量で、毎日の連続投与区、2区は1区と同量で4日間投与3日間無投与の間欠投与区とした。なお、無投与の期間は対照区と同じ小麦発酵抽出物とバチルス菌体を添加しない混合飼料を投与した。その後、試験期間中の死亡数を計測して生残率を求めた。
試験方法
IP-PA1の水抽出法:飼料2.00gに水20gを加えて懸濁し、ボルテックスミキサーで撹拌後に、5分間の超音波処理を行い、これを遠心分離(2000g 、5分)し、上清を得た。IP-PA1の特異的測定:ELISA法を用いた。
マウスマクロファージ系の培養細胞であるRAW264.7細胞(1.6×105個/100μl/ウエル)を96穴平底プレートの播種し、6時間、37℃の5%炭酸ガス培養器で培養した。その後に各被検体の希釈液を各用量、穴当たり100μlずつ加えた。各被検体溶液は、細胞培養液中で終濃度が小麦発酵抽出物がIP-PA1量として0.1ng/mlから10ng/mlになるように、バチルス菌体が1μg/mlから100μg /mlになるように被検体を培養液(10%牛胎児血清、60μg/ml アンピシリンナトリウム、50μg/ml硫酸カナマイシンを含むRPMI 1640培地)にて系列希釈して調製した。試験の陰性対照には培養液を用いた。各検体を添加し、20時間培養した後、培養上清を一部(50μl)回収し、グリエス氏の方法(NOから生じる亜硝酸を酸性条件下でスルファニルアミドとのジアゾニウム塩化合物に変化させ、それとナフチルエチレンジアミンのアゾカップリングによって生成する赤色色素を検出する方法)により、一酸化窒素の代謝物である亜硝酸濃度を測定した。
Claims (8)
- 小麦をパントエア菌で発酵して得られた小麦発酵抽出物から得られるリポ多糖及びバチルス菌体が配合されていることを特徴とする飼料添加剤。
- 小麦をパントエア菌で発酵して得られた小麦発酵抽出物から得られるリポ多糖及びバチルス菌体が配合されていることを特徴とする飼料。
- 小麦をパントエア菌で発酵して得られた小麦発酵抽出物から得られるリポ多糖及びバチルス菌体を配合することを特徴とする飼料添加剤の製造方法。
- 小麦をパントエア菌で発酵して得られた小麦発酵抽出物から得られるリポ多糖及びバチルス菌体を配合することを特徴とする飼料の製造方法。
- 小麦をパントエア菌で発酵して得られた小麦発酵抽出物から得られるリポ多糖及びバチルス菌体の有効量をペット、畜産動物又は水産動物に投与することを特徴とするペット、畜産動物又は水産動物の飼育方法。
- 小麦をパントエア菌で発酵して得られた小麦発酵抽出物から得られるリポ多糖及びバチルス菌体を有効成分として含有することを特徴とするペット、畜産又は水産用の斃死予防剤。
- 畜産又は水産用であることを特徴とする請求項2記載の飼料。
- 甲殻類又は魚類用であることを特徴とする請求項2記載の飼料。
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JP2009232793A JP2009232793A (ja) | 2009-10-15 |
JP5719497B2 true JP5719497B2 (ja) | 2015-05-20 |
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JPS60168347A (ja) * | 1984-02-14 | 1985-08-31 | Mitsui Toatsu Chem Inc | 産卵鶏用飼料 |
JP2000034233A (ja) | 1998-07-15 | 2000-02-02 | Sumitomo Forestry Co Ltd | 一酸化窒素産生抑制剤 |
JP2000217567A (ja) * | 1999-01-29 | 2000-08-08 | Yakult Honsha Co Ltd | バチルス属細菌の芽胞化方法 |
JP2003052314A (ja) * | 2001-08-10 | 2003-02-25 | Technica:Kk | 納豆菌を含有する養殖魚用飼料及びこの納豆菌を含有する養殖魚用飼料の製造方法 |
AT413191B (de) | 2002-10-11 | 2005-12-15 | Erber Ag | Futtermittel- und/oder trinkwasserzusatz für nutztiere |
KR20120031522A (ko) * | 2003-09-26 | 2012-04-03 | 바이오메디칼 리서치 그룹 인코포레이티드 | 발효 및 배양 방법, 식물발효 엑기스, 식물발효 엑기스 분말 및 이 식물발효 엑기스 배합물 |
JPWO2008023580A1 (ja) | 2006-08-24 | 2010-01-07 | 出光興産株式会社 | 動物用飼料添加剤 |
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