JP5680647B2 - 水溶性材料で被覆された棘を有する織物 - Google Patents
水溶性材料で被覆された棘を有する織物 Download PDFInfo
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- JP5680647B2 JP5680647B2 JP2012527373A JP2012527373A JP5680647B2 JP 5680647 B2 JP5680647 B2 JP 5680647B2 JP 2012527373 A JP2012527373 A JP 2012527373A JP 2012527373 A JP2012527373 A JP 2012527373A JP 5680647 B2 JP5680647 B2 JP 5680647B2
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04B—KNITTING
- D04B21/00—Warp knitting processes for the production of fabrics or articles not dependent on the use of particular machines; Fabrics or articles defined by such processes
- D04B21/10—Open-work fabrics
- D04B21/12—Open-work fabrics characterised by thread material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30317—The prosthesis having different structural features at different locations within the same prosthesis
- A61F2002/30322—The prosthesis having different structural features at different locations within the same prosthesis differing in surface structures
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
- A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0026—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in surface structures
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/003—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in adsorbability or resorbability, i.e. in adsorption or resorption time
- A61F2250/0031—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in adsorbability or resorbability, i.e. in adsorption or resorption time made from both resorbable and non-resorbable prosthetic parts, e.g. adjacent parts
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- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2501/00—Wearing apparel
- D10B2501/06—Details of garments
- D10B2501/063—Fasteners
- D10B2501/0632—Fasteners of the touch-and-close type
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- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2509/00—Medical; Hygiene
- D10B2509/08—Hernia repair mesh
Description
b)上記組成物の層を、前記棘に供給する工程
液体状態の水溶性生体適合材料を含む組成物は、液体、粘性、または糊状であってもよい。例えば、組成物は、ブラシまたは他にロールを用いて、棘に塗ることができる、または、棘をその中に浸すことのできる粘度(consistency)を有している。
WO 01/81667に記載された、15×10cm2の大きさで、棘を有する補綴用織物を準備する。ここで、棘は、ポリ乳酸(PLA)からなるモノフィラメント糸で形成されている。
図1に示したような、実施例1と同じ補綴用織物を準備する。
補綴用織物の棘に付与された混合物が溶解するのに必要な時間を評価するために、上記のように用意したサンプルを、棘が、カップリング能力を回復するまで、37℃の水の中に数秒間入れた。
図1に示したような、実施例1と同じ補綴用織物を準備する。
補綴用織物の棘に付与された混合物が溶解するのに必要な時間を評価するために、上記のように用意したサンプルを、40℃の水で湿らせた状態(kept on wipes moistened with water)で、所定時間(10、25、20秒)維持した。所定時間が経ったとき、棘のカップリング特性、及びサンプル上に残留した混合物の質量を評価した。
融点の低いPEG1000(33℃〜39℃)を用いて、40℃での被覆の安定性を評価するために、いくつかの試験が行われた。PEG1000だけで被覆されたサンプルは、40℃のオーブンの中で、24時間後に溶けた。これに対して、PEG1000/PEG4000、またはPEG1000/PEG2000の混合物が被覆された織物は、同じ条件の下で、被覆の変容を示さなかった。
図1に示したような、実施例1と同じ補綴用織物を準備する。
Claims (11)
- 織物の少なくとも2つの表面で定められる糸の配列からなり、前記織物が、少なくとも一つの表面の上に、該表面に対して外に突出する1以上の棘を有する補綴用織物において、
前記棘は、前記糸の配列から得られる熱溶融モノフィラメント糸、または生体適合性のある材料からなり、
前記棘は、水溶性で、かつ生体適合性のあるコーティング材で被覆されている、補綴用織物。 - 前記水溶性材料は、生物分解可能である、請求項1に記載の補綴用織物。
- 前記水溶性材料は、ポリエチレングリコール(PEG)、ポリビニルアセテート(PVA)、ゼラチン、ポリグルクロン酸、ヒアルロン酸、カルボキシメチルセルロース、セルロースエーテル、キトサン、及びこれらの混合物から選択される、請求項1または2に記載の補綴用織物。
- 前記水溶性材料は、40000Da以下のモル質量を有するポリエチレングリコールである、請求項1〜3の何れかに記載の補綴用織物。
- 前記モル質量は、1000〜20000Daの範囲である、請求項4に記載の補綴用織物。
- 前記水溶性材料は、10000Daのモル質量を有する、少なくとも一つのポリエチレングリコールを含む、請求項1〜5の何れかに記載の補綴用織物。
- 織物の少なくとも2つの表面で定められる糸の配列からなり、前記織物が、少なくとも一つの表面の上に、該表面に対して外に突出する1以上の棘を有する補綴用織物を被覆する方法であって、
前記棘は、前記糸の配列から得られる熱溶融モノフィラメント糸、または生体適合性のある材料からなり、
a)少なくとも液体状態の水溶性生体適合材料を含む組成物を用意する工程と、
b)前記組成物の層を、前記棘に供給する工程と
を含む、補綴用織物を被覆する方法。 - 前記工程b)は、ロールを用いて実行される、請求項7に記載の補綴用織物を被覆する方法。
- 前記組成物は、前記水溶性材料を水に可溶化し、任意に、前記組成物を、前記水溶性材料の融点に加熱することによって得られる、請求項7または8に記載の補綴用織物を被覆する方法。
- 前記組成物は、前記水溶性材料だけを、前記水溶性材料の融点に加熱することによって得られる、請求項7または8に記載の補綴用織物を被覆する方法。
- 請求項1〜6の何れかに記載の補綴用織物から製造された、または、請求項7〜10の何れかに記載の方法によって得られた補綴用織物から製造された、ヘルニアの治療用の人工器官。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR09/56038 | 2009-09-04 | ||
FR0956038A FR2949687B1 (fr) | 2009-09-04 | 2009-09-04 | Tissu avec picots revetus d'un materiau hydrosoluble |
PCT/FR2010/051843 WO2011027087A1 (fr) | 2009-09-04 | 2010-09-06 | Tissu avec picots revetus d'un materiau hydrosoluble |
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JP2013503674A JP2013503674A (ja) | 2013-02-04 |
JP5680647B2 true JP5680647B2 (ja) | 2015-03-04 |
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JP2012527373A Active JP5680647B2 (ja) | 2009-09-04 | 2010-09-06 | 水溶性材料で被覆された棘を有する織物 |
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US (3) | US9744019B2 (ja) |
EP (1) | EP2473133B1 (ja) |
JP (1) | JP5680647B2 (ja) |
AU (1) | AU2010291040B2 (ja) |
CA (1) | CA2772409C (ja) |
FR (1) | FR2949687B1 (ja) |
WO (1) | WO2011027087A1 (ja) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2949687B1 (fr) | 2009-09-04 | 2011-09-23 | Sofradim Production | Tissu avec picots revetus d'un materiau hydrosoluble |
US8435307B2 (en) | 2010-05-20 | 2013-05-07 | Ces Advancements, Llc | Reinforcement device with dissolvable layer and its use |
FR2972626B1 (fr) | 2011-03-16 | 2014-04-11 | Sofradim Production | Prothese comprenant un tricot tridimensionnel et ajoure |
WO2012142473A1 (en) | 2011-04-15 | 2012-10-18 | University Of Massachusetts | Surgical cavity drainage and closure system |
FR2977790B1 (fr) | 2011-07-13 | 2013-07-19 | Sofradim Production | Prothese pour hernie ombilicale |
FR2977789B1 (fr) | 2011-07-13 | 2013-07-19 | Sofradim Production | Prothese pour hernie ombilicale |
FR2979112B1 (fr) * | 2011-08-19 | 2013-08-16 | Sofradim Production | Tricot avec picots sur les deux faces |
US20130190857A1 (en) * | 2011-09-09 | 2013-07-25 | Endoluminal Sciences Pty Ltd. | Means for controlled sealing of endovascular devices |
FR2985170B1 (fr) | 2011-12-29 | 2014-01-24 | Sofradim Production | Prothese pour hernie inguinale |
FR2985271B1 (fr) * | 2011-12-29 | 2014-01-24 | Sofradim Production | Tricot a picots |
FR2992662B1 (fr) | 2012-06-28 | 2014-08-08 | Sofradim Production | Tricot avec picots |
FR2992547B1 (fr) | 2012-06-29 | 2015-04-24 | Sofradim Production | Prothese pour hernie |
FR2994185B1 (fr) | 2012-08-02 | 2015-07-31 | Sofradim Production | Procede de preparation d’une couche poreuse a base de chitosane |
FR2995779B1 (fr) | 2012-09-25 | 2015-09-25 | Sofradim Production | Prothese comprenant un treillis et un moyen de consolidation |
FR2995788B1 (fr) | 2012-09-25 | 2014-09-26 | Sofradim Production | Patch hemostatique et procede de preparation |
JP6338666B2 (ja) * | 2014-07-24 | 2018-06-06 | 国立研究開発法人物質・材料研究機構 | 医療用生体吸収性部材及びその製造方法 |
EP3059255B1 (en) | 2015-02-17 | 2020-05-13 | Sofradim Production | Method for preparing a chitosan-based matrix comprising a fiber reinforcement member |
EP3085337B1 (en) | 2015-04-24 | 2022-09-14 | Sofradim Production | Prosthesis for supporting a breast structure |
EP3106185B1 (en) | 2015-06-19 | 2018-04-25 | Sofradim Production | Synthetic prosthesis comprising a knit and a non porous film and method for forming same |
EP3195830B1 (en) | 2016-01-25 | 2020-11-18 | Sofradim Production | Prosthesis for hernia repair |
EP3312325B1 (en) | 2016-10-21 | 2021-09-22 | Sofradim Production | Method for forming a mesh having a barbed suture attached thereto and the mesh thus obtained |
EP3398554A1 (en) | 2017-05-02 | 2018-11-07 | Sofradim Production | Prosthesis for inguinal hernia repair |
ES2898463T3 (es) | 2017-05-02 | 2022-03-07 | Sofradim Production | Un método para hacer tejido de punto de agarre de dos lados |
WO2019079709A1 (en) | 2017-10-19 | 2019-04-25 | C.R.Bard, Inc. | SELF-AGRIPTING HERNIA PROSTHESIS |
EP3653171A1 (en) | 2018-11-16 | 2020-05-20 | Sofradim Production | Implants suitable for soft tissue repair |
CN111166532B (zh) * | 2019-12-30 | 2022-03-01 | 武汉联影智融医疗科技有限公司 | 人工关节及其制备方法 |
EP4115849A1 (en) | 2021-07-09 | 2023-01-11 | Sofradim Production | Composite implant incuding a mesh and a foam and methods associated therewith |
Family Cites Families (23)
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US4938763B1 (en) * | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
CA2002016A1 (en) * | 1988-11-21 | 1990-05-21 | Koji Miyake | Manufacturing method, continuous manufacturing method, product and manufacturing apparatus of absorbent composite |
US5254133A (en) | 1991-04-24 | 1993-10-19 | Seid Arnold S | Surgical implantation device and related method of use |
US6393673B1 (en) * | 1997-07-31 | 2002-05-28 | 3M Innovative Properties Company | Mechanical-fastening element |
US6042592A (en) * | 1997-08-04 | 2000-03-28 | Meadox Medicals, Inc. | Thin soft tissue support mesh |
DE19832634A1 (de) | 1998-07-09 | 2000-01-13 | Ethicon Endo Surgery Europe | Mehrschichtiges flächiges Implantat |
DE10019604C2 (de) * | 2000-04-20 | 2002-06-27 | Ethicon Gmbh | Implantat |
FR2807937B1 (fr) * | 2000-04-20 | 2002-08-02 | Sofradim Production | Tricot prothetique agrippant, son procede de fabrication et implant de renfort pour le traitement des deficits parietaux |
FR2807936B1 (fr) | 2000-04-20 | 2002-08-02 | Sofradim Production | Renfort de paroi abdominale pour le traitement des hernies inguinales par voie anterieure sans tension |
CA2345222A1 (en) * | 2000-04-27 | 2001-10-27 | Gerard Therrien | Corner for screen |
ATE420599T1 (de) * | 2000-05-19 | 2009-01-15 | Coapt Systems Inc | Angleichvorrichtung für gewebe |
CA2519750A1 (en) * | 2003-05-28 | 2004-12-09 | Blue Membranes Gmbh | Implants with functionalized carbon surfaces |
WO2005004868A1 (ja) * | 2003-07-15 | 2005-01-20 | Arigen, Inc. | 抗コロナウイルス剤 |
EP1642585A1 (en) * | 2004-09-27 | 2006-04-05 | Immunotech S.A. | Osteogenic oligonucleotides and uses thereof |
US7241697B2 (en) * | 2005-07-07 | 2007-07-10 | Hitachi Global Storage Technologies Netherlands Bv | Method for sensor edge control and track width definition for narrow track width devices |
US7563277B2 (en) * | 2005-10-24 | 2009-07-21 | Cook Incorporated | Removable covering for implantable frame projections |
EP2205292B1 (en) * | 2007-09-21 | 2013-05-15 | Boston Scientific Scimed, Inc. | Therapeutic agent-eluting medical devices having textured polymeric surfaces |
US8522796B2 (en) * | 2007-11-08 | 2013-09-03 | Mcneil-Ppc, Inc | Coated multi-ribbed dental tape |
FR2924330B1 (fr) * | 2007-12-03 | 2009-11-20 | Sofradim Production | Implant pour hernie parastomiale |
US9308068B2 (en) * | 2007-12-03 | 2016-04-12 | Sofradim Production | Implant for parastomal hernia |
US7810261B2 (en) * | 2008-07-24 | 2010-10-12 | Americhip, Inc. | Animated foldable card |
FR2949687B1 (fr) | 2009-09-04 | 2011-09-23 | Sofradim Production | Tissu avec picots revetus d'un materiau hydrosoluble |
FR2949688B1 (fr) * | 2009-09-04 | 2012-08-24 | Sofradim Production | Tissu avec picots revetu d'une couche microporeuse bioresorbable |
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- 2009-09-04 FR FR0956038A patent/FR2949687B1/fr not_active Expired - Fee Related
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2010
- 2010-09-06 US US13/393,867 patent/US9744019B2/en active Active
- 2010-09-06 JP JP2012527373A patent/JP5680647B2/ja active Active
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- 2010-09-06 CA CA2772409A patent/CA2772409C/fr not_active Expired - Fee Related
- 2010-09-06 EP EP10763813.2A patent/EP2473133B1/fr active Active
- 2010-09-06 WO PCT/FR2010/051843 patent/WO2011027087A1/fr active Application Filing
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US20180008390A1 (en) | 2018-01-11 |
US20200205957A1 (en) | 2020-07-02 |
US10548704B2 (en) | 2020-02-04 |
US9744019B2 (en) | 2017-08-29 |
US20120165937A1 (en) | 2012-06-28 |
JP2013503674A (ja) | 2013-02-04 |
AU2010291040A1 (en) | 2012-04-12 |
CA2772409C (fr) | 2017-09-26 |
FR2949687A1 (fr) | 2011-03-11 |
FR2949687B1 (fr) | 2011-09-23 |
WO2011027087A1 (fr) | 2011-03-10 |
AU2010291040B2 (en) | 2015-07-02 |
CA2772409A1 (fr) | 2011-03-10 |
EP2473133B1 (fr) | 2014-04-09 |
EP2473133A1 (fr) | 2012-07-11 |
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