JP5631735B2 - 抗菌組成物 - Google Patents
抗菌組成物 Download PDFInfo
- Publication number
- JP5631735B2 JP5631735B2 JP2010516568A JP2010516568A JP5631735B2 JP 5631735 B2 JP5631735 B2 JP 5631735B2 JP 2010516568 A JP2010516568 A JP 2010516568A JP 2010516568 A JP2010516568 A JP 2010516568A JP 5631735 B2 JP5631735 B2 JP 5631735B2
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- composition
- chloride
- component
- antimicrobial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title claims description 247
- 230000000844 anti-bacterial effect Effects 0.000 title claims description 35
- -1 halide ion Chemical class 0.000 claims description 98
- 230000000845 anti-microbial effect Effects 0.000 claims description 54
- 239000004599 antimicrobial Substances 0.000 claims description 49
- 244000005700 microbiome Species 0.000 claims description 47
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 38
- 239000003242 anti bacterial agent Substances 0.000 claims description 37
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 29
- 150000001875 compounds Chemical class 0.000 claims description 28
- 239000002798 polar solvent Substances 0.000 claims description 28
- 230000000813 microbial effect Effects 0.000 claims description 22
- 125000000217 alkyl group Chemical group 0.000 claims description 18
- 150000003856 quaternary ammonium compounds Chemical class 0.000 claims description 18
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 16
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 15
- 230000000694 effects Effects 0.000 claims description 14
- 229940027983 antiseptic and disinfectant quaternary ammonium compound Drugs 0.000 claims description 13
- 230000015572 biosynthetic process Effects 0.000 claims description 12
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 claims description 12
- UQEAIHBTYFGYIE-UHFFFAOYSA-N hexamethyldisiloxane Chemical group C[Si](C)(C)O[Si](C)(C)C UQEAIHBTYFGYIE-UHFFFAOYSA-N 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 9
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 8
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 claims description 8
- RUPBZQFQVRMKDG-UHFFFAOYSA-M Didecyldimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC RUPBZQFQVRMKDG-UHFFFAOYSA-M 0.000 claims description 7
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims description 7
- LLEMOWNGBBNAJR-UHFFFAOYSA-N biphenyl-2-ol Chemical compound OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 claims description 6
- 229960004670 didecyldimethylammonium chloride Drugs 0.000 claims description 6
- JMHWNJGXUIJPKG-UHFFFAOYSA-N CC(=O)O[SiH](CC=C)OC(C)=O Chemical compound CC(=O)O[SiH](CC=C)OC(C)=O JMHWNJGXUIJPKG-UHFFFAOYSA-N 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- ZILVNHNSYBNLSZ-UHFFFAOYSA-N 2-(diaminomethylideneamino)guanidine Chemical compound NC(N)=NNC(N)=N ZILVNHNSYBNLSZ-UHFFFAOYSA-N 0.000 claims description 4
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 4
- YFCGDEUVHLPRCZ-UHFFFAOYSA-N [dimethyl(trimethylsilyloxy)silyl]oxy-dimethyl-trimethylsilyloxysilane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C YFCGDEUVHLPRCZ-UHFFFAOYSA-N 0.000 claims description 3
- SCXCDVTWABNWLW-UHFFFAOYSA-M decyl-dimethyl-octylazanium;chloride Chemical compound [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCC SCXCDVTWABNWLW-UHFFFAOYSA-M 0.000 claims description 3
- FBZANXDWQAVSTQ-UHFFFAOYSA-N dodecamethylpentasiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C FBZANXDWQAVSTQ-UHFFFAOYSA-N 0.000 claims description 3
- 239000004306 orthophenyl phenol Substances 0.000 claims description 3
- 235000010292 orthophenyl phenol Nutrition 0.000 claims description 3
- CGLRMJMKUHEFQB-UHFFFAOYSA-N 1-bromo-1-nitropropane Chemical compound CCC(Br)[N+]([O-])=O CGLRMJMKUHEFQB-UHFFFAOYSA-N 0.000 claims description 2
- JBIROUFYLSSYDX-UHFFFAOYSA-M benzododecinium chloride Chemical compound [Cl-].CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 JBIROUFYLSSYDX-UHFFFAOYSA-M 0.000 claims description 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 2
- OCBHHZMJRVXXQK-UHFFFAOYSA-M benzyl-dimethyl-tetradecylazanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 OCBHHZMJRVXXQK-UHFFFAOYSA-M 0.000 claims description 2
- 229940087203 dodecamethylpentasiloxane Drugs 0.000 claims description 2
- CZTYEHPJXNKADU-UHFFFAOYSA-M dodecyl-dimethyl-tetradecylazanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCC CZTYEHPJXNKADU-UHFFFAOYSA-M 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 claims description 2
- 239000000463 material Substances 0.000 description 49
- 238000012360 testing method Methods 0.000 description 47
- 239000000084 colloidal system Substances 0.000 description 36
- 239000000243 solution Substances 0.000 description 30
- 241000894006 Bacteria Species 0.000 description 28
- 239000000725 suspension Substances 0.000 description 27
- 239000003795 chemical substances by application Substances 0.000 description 17
- 238000009472 formulation Methods 0.000 description 17
- 239000000047 product Substances 0.000 description 17
- 230000001580 bacterial effect Effects 0.000 description 15
- 229920003023 plastic Polymers 0.000 description 13
- 239000004033 plastic Substances 0.000 description 13
- 239000002245 particle Substances 0.000 description 11
- 239000004094 surface-active agent Substances 0.000 description 11
- 125000003118 aryl group Chemical group 0.000 description 10
- 241001646716 Escherichia coli K-12 Species 0.000 description 9
- 230000009467 reduction Effects 0.000 description 9
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 8
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 8
- 238000000576 coating method Methods 0.000 description 8
- 238000004659 sterilization and disinfection Methods 0.000 description 8
- 238000010200 validation analysis Methods 0.000 description 8
- 238000001246 colloidal dispersion Methods 0.000 description 7
- 230000003472 neutralizing effect Effects 0.000 description 7
- 229920001296 polysiloxane Polymers 0.000 description 7
- 239000000758 substrate Substances 0.000 description 7
- 241000233866 Fungi Species 0.000 description 6
- 125000002877 alkyl aryl group Chemical group 0.000 description 6
- 125000003710 aryl alkyl group Chemical group 0.000 description 6
- UREZNYTWGJKWBI-UHFFFAOYSA-M benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 description 6
- 229910052799 carbon Inorganic materials 0.000 description 6
- 125000004432 carbon atom Chemical group C* 0.000 description 6
- 238000004140 cleaning Methods 0.000 description 6
- 125000000623 heterocyclic group Chemical group 0.000 description 6
- 230000002147 killing effect Effects 0.000 description 6
- 239000008204 material by function Substances 0.000 description 6
- 229920006324 polyoxymethylene Polymers 0.000 description 6
- 238000010998 test method Methods 0.000 description 6
- 231100000331 toxic Toxicity 0.000 description 6
- 230000002588 toxic effect Effects 0.000 description 6
- 231100000419 toxicity Toxicity 0.000 description 6
- 230000001988 toxicity Effects 0.000 description 6
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 5
- 241000700605 Viruses Species 0.000 description 5
- 229940121375 antifungal agent Drugs 0.000 description 5
- 239000003899 bactericide agent Substances 0.000 description 5
- 230000008901 benefit Effects 0.000 description 5
- 229960000686 benzalkonium chloride Drugs 0.000 description 5
- 230000003115 biocidal effect Effects 0.000 description 5
- 229920001577 copolymer Polymers 0.000 description 5
- 125000000753 cycloalkyl group Chemical group 0.000 description 5
- 229920001971 elastomer Polymers 0.000 description 5
- 239000000835 fiber Substances 0.000 description 5
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 description 5
- 208000015181 infectious disease Diseases 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- QYSGYZVSCZSLHT-UHFFFAOYSA-N octafluoropropane Chemical compound FC(F)(F)C(F)(F)C(F)(F)F QYSGYZVSCZSLHT-UHFFFAOYSA-N 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 4
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 4
- 239000004677 Nylon Substances 0.000 description 4
- 239000004698 Polyethylene Substances 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 4
- 239000004793 Polystyrene Substances 0.000 description 4
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 4
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 4
- 206010041925 Staphylococcal infections Diseases 0.000 description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 4
- 230000001070 adhesive effect Effects 0.000 description 4
- 150000001298 alcohols Chemical class 0.000 description 4
- 244000052616 bacterial pathogen Species 0.000 description 4
- 239000003139 biocide Substances 0.000 description 4
- SXPWTBGAZSPLHA-UHFFFAOYSA-M cetalkonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 SXPWTBGAZSPLHA-UHFFFAOYSA-M 0.000 description 4
- 229960000228 cetalkonium chloride Drugs 0.000 description 4
- 239000011248 coating agent Substances 0.000 description 4
- 230000007423 decrease Effects 0.000 description 4
- 230000007613 environmental effect Effects 0.000 description 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 4
- 239000008241 heterogeneous mixture Substances 0.000 description 4
- 238000011081 inoculation Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 230000007774 longterm Effects 0.000 description 4
- 208000015688 methicillin-resistant staphylococcus aureus infectious disease Diseases 0.000 description 4
- 239000000693 micelle Substances 0.000 description 4
- 229920001778 nylon Polymers 0.000 description 4
- 244000052769 pathogen Species 0.000 description 4
- 229920002647 polyamide Polymers 0.000 description 4
- 229920000728 polyester Polymers 0.000 description 4
- 229920000573 polyethylene Polymers 0.000 description 4
- 229920000139 polyethylene terephthalate Polymers 0.000 description 4
- 239000005020 polyethylene terephthalate Substances 0.000 description 4
- 229920001155 polypropylene Polymers 0.000 description 4
- 239000004814 polyurethane Substances 0.000 description 4
- 229920002635 polyurethane Polymers 0.000 description 4
- 229920000915 polyvinyl chloride Polymers 0.000 description 4
- 239000004800 polyvinyl chloride Substances 0.000 description 4
- 239000005033 polyvinylidene chloride Substances 0.000 description 4
- 230000002829 reductive effect Effects 0.000 description 4
- 239000005060 rubber Substances 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 239000000565 sealant Substances 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 238000005507 spraying Methods 0.000 description 4
- 239000012085 test solution Substances 0.000 description 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
- PUAQLLVFLMYYJJ-UHFFFAOYSA-N 2-aminopropiophenone Chemical compound CC(N)C(=O)C1=CC=CC=C1 PUAQLLVFLMYYJJ-UHFFFAOYSA-N 0.000 description 3
- QPRQEDXDYOZYLA-UHFFFAOYSA-N 2-methylbutan-1-ol Chemical compound CCC(C)CO QPRQEDXDYOZYLA-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 3
- LVDKZNITIUWNER-UHFFFAOYSA-N Bronopol Chemical compound OCC(Br)(CO)[N+]([O-])=O LVDKZNITIUWNER-UHFFFAOYSA-N 0.000 description 3
- CXRFDZFCGOPDTD-UHFFFAOYSA-M Cetrimide Chemical compound [Br-].CCCCCCCCCCCCCC[N+](C)(C)C CXRFDZFCGOPDTD-UHFFFAOYSA-M 0.000 description 3
- 239000004593 Epoxy Substances 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- 229920000106 Liquid crystal polymer Polymers 0.000 description 3
- 239000004977 Liquid-crystal polymers (LCPs) Substances 0.000 description 3
- 241000186779 Listeria monocytogenes Species 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 3
- AMQJEAYHLZJPGS-UHFFFAOYSA-N N-Pentanol Chemical compound CCCCCO AMQJEAYHLZJPGS-UHFFFAOYSA-N 0.000 description 3
- 229920000459 Nitrile rubber Polymers 0.000 description 3
- 229930040373 Paraformaldehyde Natural products 0.000 description 3
- 239000004952 Polyamide Substances 0.000 description 3
- 239000004642 Polyimide Substances 0.000 description 3
- 239000004721 Polyphenylene oxide Substances 0.000 description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 3
- 229920000297 Rayon Polymers 0.000 description 3
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 3
- 150000001241 acetals Chemical class 0.000 description 3
- 238000007792 addition Methods 0.000 description 3
- 239000013466 adhesive and sealant Substances 0.000 description 3
- 125000003342 alkenyl group Chemical group 0.000 description 3
- 150000003973 alkyl amines Chemical class 0.000 description 3
- 229920003180 amino resin Polymers 0.000 description 3
- 230000000843 anti-fungal effect Effects 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 239000003429 antifungal agent Substances 0.000 description 3
- 229960003237 betaine Drugs 0.000 description 3
- 230000032770 biofilm formation Effects 0.000 description 3
- 229920002678 cellulose Polymers 0.000 description 3
- 239000001913 cellulose Substances 0.000 description 3
- 229920002301 cellulose acetate Polymers 0.000 description 3
- 239000000919 ceramic Substances 0.000 description 3
- 229960001927 cetylpyridinium chloride Drugs 0.000 description 3
- 239000004567 concrete Substances 0.000 description 3
- 230000034994 death Effects 0.000 description 3
- 231100000517 death Toxicity 0.000 description 3
- 230000000855 fungicidal effect Effects 0.000 description 3
- 239000000417 fungicide Substances 0.000 description 3
- 150000004676 glycans Chemical class 0.000 description 3
- 230000002209 hydrophobic effect Effects 0.000 description 3
- 239000005414 inactive ingredient Substances 0.000 description 3
- 229940115931 listeria monocytogenes Drugs 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 3
- 229920001707 polybutylene terephthalate Polymers 0.000 description 3
- 239000004417 polycarbonate Substances 0.000 description 3
- 229920000515 polycarbonate Polymers 0.000 description 3
- 229920001721 polyimide Polymers 0.000 description 3
- 229920001470 polyketone Polymers 0.000 description 3
- 239000004926 polymethyl methacrylate Substances 0.000 description 3
- 229920001955 polyphenylene ether Polymers 0.000 description 3
- 229920006380 polyphenylene oxide Polymers 0.000 description 3
- 229920001282 polysaccharide Polymers 0.000 description 3
- 239000005017 polysaccharide Substances 0.000 description 3
- 229920002223 polystyrene Polymers 0.000 description 3
- 229920002689 polyvinyl acetate Polymers 0.000 description 3
- 239000011118 polyvinyl acetate Substances 0.000 description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 description 3
- 229910052573 porcelain Inorganic materials 0.000 description 3
- 238000013207 serial dilution Methods 0.000 description 3
- 229920003048 styrene butadiene rubber Polymers 0.000 description 3
- 125000001424 substituent group Chemical group 0.000 description 3
- 230000004083 survival effect Effects 0.000 description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- HXVNBWAKAOHACI-UHFFFAOYSA-N 2,4-dimethyl-3-pentanone Chemical compound CC(C)C(=O)C(C)C HXVNBWAKAOHACI-UHFFFAOYSA-N 0.000 description 2
- OAYXUHPQHDHDDZ-UHFFFAOYSA-N 2-(2-butoxyethoxy)ethanol Chemical compound CCCCOCCOCCO OAYXUHPQHDHDDZ-UHFFFAOYSA-N 0.000 description 2
- RXGUIWHIADMCFC-UHFFFAOYSA-N 2-Methylpropyl 2-methylpropionate Chemical compound CC(C)COC(=O)C(C)C RXGUIWHIADMCFC-UHFFFAOYSA-N 0.000 description 2
- XLLIQLLCWZCATF-UHFFFAOYSA-N 2-methoxyethyl acetate Chemical compound COCCOC(C)=O XLLIQLLCWZCATF-UHFFFAOYSA-N 0.000 description 2
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 description 2
- ZPVFWPFBNIEHGJ-UHFFFAOYSA-N 2-octanone Chemical compound CCCCCCC(C)=O ZPVFWPFBNIEHGJ-UHFFFAOYSA-N 0.000 description 2
- PFCHFHIRKBAQGU-UHFFFAOYSA-N 3-hexanone Chemical compound CCCC(=O)CC PFCHFHIRKBAQGU-UHFFFAOYSA-N 0.000 description 2
- FFWSICBKRCICMR-UHFFFAOYSA-N 5-methyl-2-hexanone Chemical compound CC(C)CCC(C)=O FFWSICBKRCICMR-UHFFFAOYSA-N 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Natural products CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 2
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 description 2
- 241000271566 Aves Species 0.000 description 2
- 241000222122 Candida albicans Species 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- 241000195493 Cryptophyta Species 0.000 description 2
- 241000194032 Enterococcus faecalis Species 0.000 description 2
- 230000005526 G1 to G0 transition Effects 0.000 description 2
- 241000711549 Hepacivirus C Species 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 241000124008 Mammalia Species 0.000 description 2
- 229920000877 Melamine resin Polymers 0.000 description 2
- 241000187480 Mycobacterium smegmatis Species 0.000 description 2
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 description 2
- 239000007977 PBT buffer Substances 0.000 description 2
- 241000233622 Phytophthora infestans Species 0.000 description 2
- 239000004734 Polyphenylene sulfide Substances 0.000 description 2
- 241000725643 Respiratory syncytial virus Species 0.000 description 2
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 description 2
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 2
- 229920001807 Urea-formaldehyde Polymers 0.000 description 2
- 241000607447 Yersinia enterocolitica Species 0.000 description 2
- YRKCREAYFQTBPV-UHFFFAOYSA-N acetylacetone Chemical compound CC(=O)CC(C)=O YRKCREAYFQTBPV-UHFFFAOYSA-N 0.000 description 2
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 2
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 2
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 2
- 229920000180 alkyd Polymers 0.000 description 2
- 150000001450 anions Chemical class 0.000 description 2
- 230000000656 anti-yeast Effects 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 229960001950 benzethonium chloride Drugs 0.000 description 2
- 239000007844 bleaching agent Substances 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 229940006460 bromide ion Drugs 0.000 description 2
- 206010006451 bronchitis Diseases 0.000 description 2
- 229960003168 bronopol Drugs 0.000 description 2
- DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 description 2
- BTANRVKWQNVYAZ-UHFFFAOYSA-N butan-2-ol Chemical compound CCC(C)O BTANRVKWQNVYAZ-UHFFFAOYSA-N 0.000 description 2
- DKPFZGUDAPQIHT-UHFFFAOYSA-N butyl acetate Chemical compound CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 description 2
- 229940095731 candida albicans Drugs 0.000 description 2
- 239000003093 cationic surfactant Substances 0.000 description 2
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 2
- 230000001332 colony forming effect Effects 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 239000007799 cork Substances 0.000 description 2
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 2
- 239000000645 desinfectant Substances 0.000 description 2
- 230000000249 desinfective effect Effects 0.000 description 2
- SWXVUIWOUIDPGS-UHFFFAOYSA-N diacetone alcohol Chemical compound CC(=O)CC(C)(C)O SWXVUIWOUIDPGS-UHFFFAOYSA-N 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 229940032049 enterococcus faecalis Drugs 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- LZCLXQDLBQLTDK-UHFFFAOYSA-N ethyl 2-hydroxypropanoate Chemical compound CCOC(=O)C(C)O LZCLXQDLBQLTDK-UHFFFAOYSA-N 0.000 description 2
- 239000005038 ethylene vinyl acetate Substances 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 239000010419 fine particle Substances 0.000 description 2
- 238000009408 flooring Methods 0.000 description 2
- 229920002313 fluoropolymer Polymers 0.000 description 2
- 239000004811 fluoropolymer Substances 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- IVJISJACKSSFGE-UHFFFAOYSA-N formaldehyde;1,3,5-triazine-2,4,6-triamine Chemical compound O=C.NC1=NC(N)=NC(N)=N1 IVJISJACKSSFGE-UHFFFAOYSA-N 0.000 description 2
- 150000002334 glycols Chemical class 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 229910001385 heavy metal Inorganic materials 0.000 description 2
- 125000005842 heteroatom Chemical group 0.000 description 2
- 239000012456 homogeneous solution Substances 0.000 description 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 230000002458 infectious effect Effects 0.000 description 2
- 239000012212 insulator Substances 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 description 2
- HJOVHMDZYOCNQW-UHFFFAOYSA-N isophorone Chemical compound CC1=CC(=O)CC(C)(C)C1 HJOVHMDZYOCNQW-UHFFFAOYSA-N 0.000 description 2
- 150000002576 ketones Chemical class 0.000 description 2
- 231100000053 low toxicity Toxicity 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 description 2
- 238000006386 neutralization reaction Methods 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000000123 paper Substances 0.000 description 2
- XNLICIUVMPYHGG-UHFFFAOYSA-N pentan-2-one Chemical compound CCCC(C)=O XNLICIUVMPYHGG-UHFFFAOYSA-N 0.000 description 2
- FDPIMTJIUBPUKL-UHFFFAOYSA-N pentan-3-one Chemical compound CCC(=O)CC FDPIMTJIUBPUKL-UHFFFAOYSA-N 0.000 description 2
- 238000009428 plumbing Methods 0.000 description 2
- 238000005498 polishing Methods 0.000 description 2
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 2
- 229920002492 poly(sulfone) Polymers 0.000 description 2
- 229920001748 polybutylene Polymers 0.000 description 2
- 239000011116 polymethylpentene Substances 0.000 description 2
- 229920000306 polymethylpentene Polymers 0.000 description 2
- ODGAOXROABLFNM-UHFFFAOYSA-N polynoxylin Chemical compound O=C.NC(N)=O ODGAOXROABLFNM-UHFFFAOYSA-N 0.000 description 2
- 229920005862 polyol Polymers 0.000 description 2
- 150000003077 polyols Chemical class 0.000 description 2
- 229920000069 polyphenylene sulfide Polymers 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- YKYONYBAUNKHLG-UHFFFAOYSA-N propyl acetate Chemical compound CCCOC(C)=O YKYONYBAUNKHLG-UHFFFAOYSA-N 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 239000004576 sand Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- SFVFIFLLYFPGHH-UHFFFAOYSA-M stearalkonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 SFVFIFLLYFPGHH-UHFFFAOYSA-M 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 229920001909 styrene-acrylic polymer Polymers 0.000 description 2
- 125000000547 substituted alkyl group Chemical group 0.000 description 2
- 229920002994 synthetic fiber Polymers 0.000 description 2
- 229920002725 thermoplastic elastomer Polymers 0.000 description 2
- 229910052718 tin Inorganic materials 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 229920006305 unsaturated polyester Polymers 0.000 description 2
- 231100000925 very toxic Toxicity 0.000 description 2
- 239000002023 wood Substances 0.000 description 2
- 229940098232 yersinia enterocolitica Drugs 0.000 description 2
- ZQLSDTDQXONGNN-UHFFFAOYSA-N (2-methyl-2-phenoxypentadecan-3-yl)azanium;bromide Chemical compound [Br-].CCCCCCCCCCCCC([NH3+])C(C)(C)OC1=CC=CC=C1 ZQLSDTDQXONGNN-UHFFFAOYSA-N 0.000 description 1
- DAFHKNAQFPVRKR-UHFFFAOYSA-N (3-hydroxy-2,2,4-trimethylpentyl) 2-methylpropanoate Chemical compound CC(C)C(O)C(C)(C)COC(=O)C(C)C DAFHKNAQFPVRKR-UHFFFAOYSA-N 0.000 description 1
- 229940058015 1,3-butylene glycol Drugs 0.000 description 1
- XAJJLRPVAXHVSL-UHFFFAOYSA-L 1-hexadecylpyridin-1-ium trimethyl(oxiran-2-ylmethyl)azanium dichloride Chemical compound [Cl-].C(C1CO1)[N+](C)(C)C.[Cl-].C(CCCCCCCCCCCCCCC)[N+]1=CC=CC=C1 XAJJLRPVAXHVSL-UHFFFAOYSA-L 0.000 description 1
- FPZWZCWUIYYYBU-UHFFFAOYSA-N 2-(2-ethoxyethoxy)ethyl acetate Chemical compound CCOCCOCCOC(C)=O FPZWZCWUIYYYBU-UHFFFAOYSA-N 0.000 description 1
- SBASXUCJHJRPEV-UHFFFAOYSA-N 2-(2-methoxyethoxy)ethanol Chemical compound COCCOCCO SBASXUCJHJRPEV-UHFFFAOYSA-N 0.000 description 1
- XNWFRZJHXBZDAG-UHFFFAOYSA-N 2-METHOXYETHANOL Chemical compound COCCO XNWFRZJHXBZDAG-UHFFFAOYSA-N 0.000 description 1
- PTTPXKJBFFKCEK-UHFFFAOYSA-N 2-Methyl-4-heptanone Chemical compound CC(C)CC(=O)CC(C)C PTTPXKJBFFKCEK-UHFFFAOYSA-N 0.000 description 1
- QQZOPKMRPOGIEB-UHFFFAOYSA-N 2-Oxohexane Chemical compound CCCCC(C)=O QQZOPKMRPOGIEB-UHFFFAOYSA-N 0.000 description 1
- JTXMVXSTHSMVQF-UHFFFAOYSA-N 2-acetyloxyethyl acetate Chemical compound CC(=O)OCCOC(C)=O JTXMVXSTHSMVQF-UHFFFAOYSA-N 0.000 description 1
- POAOYUHQDCAZBD-UHFFFAOYSA-N 2-butoxyethanol Chemical compound CCCCOCCO POAOYUHQDCAZBD-UHFFFAOYSA-N 0.000 description 1
- NQBXSWAWVZHKBZ-UHFFFAOYSA-N 2-butoxyethyl acetate Chemical compound CCCCOCCOC(C)=O NQBXSWAWVZHKBZ-UHFFFAOYSA-N 0.000 description 1
- ZNQVEEAIQZEUHB-UHFFFAOYSA-N 2-ethoxyethanol Chemical compound CCOCCO ZNQVEEAIQZEUHB-UHFFFAOYSA-N 0.000 description 1
- SVONRAPFKPVNKG-UHFFFAOYSA-N 2-ethoxyethyl acetate Chemical compound CCOCCOC(C)=O SVONRAPFKPVNKG-UHFFFAOYSA-N 0.000 description 1
- WOYWLLHHWAMFCB-UHFFFAOYSA-N 2-ethylhexyl acetate Chemical compound CCCCC(CC)COC(C)=O WOYWLLHHWAMFCB-UHFFFAOYSA-N 0.000 description 1
- UPGSWASWQBLSKZ-UHFFFAOYSA-N 2-hexoxyethanol Chemical compound CCCCCCOCCO UPGSWASWQBLSKZ-UHFFFAOYSA-N 0.000 description 1
- IEBAJFDSHJYDCK-UHFFFAOYSA-N 2-methylundecan-4-one Chemical compound CCCCCCCC(=O)CC(C)C IEBAJFDSHJYDCK-UHFFFAOYSA-N 0.000 description 1
- HCGFUIQPSOCUHI-UHFFFAOYSA-N 2-propan-2-yloxyethanol Chemical compound CC(C)OCCO HCGFUIQPSOCUHI-UHFFFAOYSA-N 0.000 description 1
- JSGVZVOGOQILFM-UHFFFAOYSA-N 3-methoxy-1-butanol Chemical compound COC(C)CCO JSGVZVOGOQILFM-UHFFFAOYSA-N 0.000 description 1
- RHLVCLIPMVJYKS-UHFFFAOYSA-N 3-octanone Chemical compound CCCCCC(=O)CC RHLVCLIPMVJYKS-UHFFFAOYSA-N 0.000 description 1
- SHOJXDKTYKFBRD-UHFFFAOYSA-N 4-Methyl-3-penten-2-one, 9CI Chemical compound CC(C)=CC(C)=O SHOJXDKTYKFBRD-UHFFFAOYSA-N 0.000 description 1
- KOKPBCHLPVDQTK-UHFFFAOYSA-N 4-methoxy-4-methylpentan-2-one Chemical compound COC(C)(C)CC(C)=O KOKPBCHLPVDQTK-UHFFFAOYSA-N 0.000 description 1
- VGVHNLRUAMRIEW-UHFFFAOYSA-N 4-methylcyclohexan-1-one Chemical compound CC1CCC(=O)CC1 VGVHNLRUAMRIEW-UHFFFAOYSA-N 0.000 description 1
- 241000588626 Acinetobacter baumannii Species 0.000 description 1
- 241000588624 Acinetobacter calcoaceticus Species 0.000 description 1
- 241000186361 Actinobacteria <class> Species 0.000 description 1
- 241000607525 Aeromonas salmonicida Species 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 241000223602 Alternaria alternata Species 0.000 description 1
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical class [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 1
- 241000203069 Archaea Species 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- 241000228197 Aspergillus flavus Species 0.000 description 1
- 241001225321 Aspergillus fumigatus Species 0.000 description 1
- 241000228245 Aspergillus niger Species 0.000 description 1
- 244000063299 Bacillus subtilis Species 0.000 description 1
- 235000014469 Bacillus subtilis Nutrition 0.000 description 1
- 241000588779 Bordetella bronchiseptica Species 0.000 description 1
- 241000186146 Brevibacterium Species 0.000 description 1
- 241000589513 Burkholderia cepacia Species 0.000 description 1
- MRABAEUHTLLEML-UHFFFAOYSA-N Butyl lactate Chemical compound CCCCOC(=O)C(C)O MRABAEUHTLLEML-UHFFFAOYSA-N 0.000 description 1
- 241001647378 Chlamydia psittaci Species 0.000 description 1
- 241000207199 Citrus Species 0.000 description 1
- 241000193163 Clostridioides difficile Species 0.000 description 1
- 241000193403 Clostridium Species 0.000 description 1
- 208000000655 Distemper Diseases 0.000 description 1
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 1
- 241000588697 Enterobacter cloacae Species 0.000 description 1
- 240000002989 Euphorbia neriifolia Species 0.000 description 1
- 208000004729 Feline Leukemia Diseases 0.000 description 1
- 241000714201 Feline calicivirus Species 0.000 description 1
- 241000725579 Feline coronavirus Species 0.000 description 1
- 241001280522 Feline picornavirus Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
- 241000223221 Fusarium oxysporum Species 0.000 description 1
- 241000193385 Geobacillus stearothermophilus Species 0.000 description 1
- 244000168141 Geotrichum candidum Species 0.000 description 1
- 235000017388 Geotrichum candidum Nutrition 0.000 description 1
- 241000700721 Hepatitis B virus Species 0.000 description 1
- 208000009889 Herpes Simplex Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 241000725303 Human immunodeficiency virus Species 0.000 description 1
- 241000713772 Human immunodeficiency virus 1 Species 0.000 description 1
- 241000588915 Klebsiella aerogenes Species 0.000 description 1
- 241000588747 Klebsiella pneumoniae Species 0.000 description 1
- 241000589242 Legionella pneumophila Species 0.000 description 1
- 241001233242 Lontra Species 0.000 description 1
- 208000006758 Marek Disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical class CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 description 1
- 241000204031 Mycoplasma Species 0.000 description 1
- 208000010359 Newcastle Disease Diseases 0.000 description 1
- 241001263478 Norovirus Species 0.000 description 1
- 241000606856 Pasteurella multocida Species 0.000 description 1
- 241001507673 Penicillium digitatum Species 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical group [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 240000005428 Pistacia lentiscus Species 0.000 description 1
- 229920001944 Plastisol Polymers 0.000 description 1
- 229930182556 Polyacetal Natural products 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- 241000588770 Proteus mirabilis Species 0.000 description 1
- 241000588767 Proteus vulgaris Species 0.000 description 1
- 241000589776 Pseudomonas putida Species 0.000 description 1
- 241000287531 Psittacidae Species 0.000 description 1
- 206010037742 Rabies Diseases 0.000 description 1
- 241000235546 Rhizopus stolonifer Species 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 241001138501 Salmonella enterica Species 0.000 description 1
- 241001354013 Salmonella enterica subsp. enterica serovar Enteritidis Species 0.000 description 1
- 241000293869 Salmonella enterica subsp. enterica serovar Typhimurium Species 0.000 description 1
- 241000607715 Serratia marcescens Species 0.000 description 1
- 241000607764 Shigella dysenteriae Species 0.000 description 1
- 241000607762 Shigella flexneri Species 0.000 description 1
- 241000607760 Shigella sonnei Species 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 241000191963 Staphylococcus epidermidis Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 241000193996 Streptococcus pyogenes Species 0.000 description 1
- 241000701093 Suid alphaherpesvirus 1 Species 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 description 1
- 241000223260 Trichoderma harzianum Species 0.000 description 1
- 241000223238 Trichophyton Species 0.000 description 1
- 241001459572 Trichophyton interdigitale Species 0.000 description 1
- 241001045770 Trichophyton mentagrophytes Species 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 206010046865 Vaccinia virus infection Diseases 0.000 description 1
- 108010059993 Vancomycin Proteins 0.000 description 1
- 241000607598 Vibrio Species 0.000 description 1
- 241000544286 Vibrio anguillarum Species 0.000 description 1
- 241000520892 Xanthomonas axonopodis Species 0.000 description 1
- AKGZDINYLOSBTE-UHFFFAOYSA-N [(e)-n'-(diaminomethylideneamino)carbamimidoyl]azanium;chloride Chemical compound Cl.NC(=N)NN=C(N)N AKGZDINYLOSBTE-UHFFFAOYSA-N 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 229940022663 acetate Drugs 0.000 description 1
- KXKVLQRXCPHEJC-UHFFFAOYSA-N acetic acid trimethyl ester Natural products COC(C)=O KXKVLQRXCPHEJC-UHFFFAOYSA-N 0.000 description 1
- 229920006243 acrylic copolymer Polymers 0.000 description 1
- 229920001893 acrylonitrile styrene Polymers 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 239000003619 algicide Substances 0.000 description 1
- 229940072049 amyl acetate Drugs 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 150000008064 anhydrides Chemical class 0.000 description 1
- PGMYKACGEOXYJE-UHFFFAOYSA-N anhydrous amyl acetate Natural products CCCCCOC(C)=O PGMYKACGEOXYJE-UHFFFAOYSA-N 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 230000001098 anti-algal effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical class [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 1
- 229940091771 aspergillus fumigatus Drugs 0.000 description 1
- 239000010426 asphalt Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229960001716 benzalkonium Drugs 0.000 description 1
- 235000012206 bottled water Nutrition 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- 235000019437 butane-1,3-diol Nutrition 0.000 description 1
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 description 1
- 208000014058 canine distemper Diseases 0.000 description 1
- 239000011111 cardboard Substances 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 229960002798 cetrimide Drugs 0.000 description 1
- 229960000800 cetrimonium bromide Drugs 0.000 description 1
- WOWHHFRSBJGXCM-UHFFFAOYSA-M cetyltrimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)C WOWHHFRSBJGXCM-UHFFFAOYSA-M 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 239000004927 clay Substances 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 230000001461 cytolytic effect Effects 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- HPHYMAFVPDYIGP-UHFFFAOYSA-N didecyl(methyl)azanium;chloride Chemical compound Cl.CCCCCCCCCCN(C)CCCCCCCCCC HPHYMAFVPDYIGP-UHFFFAOYSA-N 0.000 description 1
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- XJWSAJYUBXQQDR-UHFFFAOYSA-M dodecyltrimethylammonium bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)C XJWSAJYUBXQQDR-UHFFFAOYSA-M 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000002296 dynamic light scattering Methods 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 229940092559 enterobacter aerogenes Drugs 0.000 description 1
- 229940116333 ethyl lactate Drugs 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000011440 grout Substances 0.000 description 1
- 239000000383 hazardous chemical Substances 0.000 description 1
- 231100000206 health hazard Toxicity 0.000 description 1
- CATSNJVOTSVZJV-UHFFFAOYSA-N heptan-2-one Chemical compound CCCCCC(C)=O CATSNJVOTSVZJV-UHFFFAOYSA-N 0.000 description 1
- NGAZZOYFWWSOGK-UHFFFAOYSA-N heptan-3-one Chemical compound CCCCC(=O)CC NGAZZOYFWWSOGK-UHFFFAOYSA-N 0.000 description 1
- MNWFXJYAOYHMED-UHFFFAOYSA-M heptanoate Chemical compound CCCCCCC([O-])=O MNWFXJYAOYHMED-UHFFFAOYSA-M 0.000 description 1
- 150000002391 heterocyclic compounds Chemical class 0.000 description 1
- 229940051250 hexylene glycol Drugs 0.000 description 1
- 239000012943 hotmelt Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 208000005562 infectious bovine rhinotracheitis Diseases 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 239000011810 insulating material Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-M iodide Chemical compound [I-] XMBWDFGMSWQBCA-UHFFFAOYSA-M 0.000 description 1
- 229940006461 iodide ion Drugs 0.000 description 1
- 229940035535 iodophors Drugs 0.000 description 1
- GJRQTCIYDGXPES-UHFFFAOYSA-N iso-butyl acetate Natural products CC(C)COC(C)=O GJRQTCIYDGXPES-UHFFFAOYSA-N 0.000 description 1
- FGKJLKRYENPLQH-UHFFFAOYSA-M isocaproate Chemical compound CC(C)CCC([O-])=O FGKJLKRYENPLQH-UHFFFAOYSA-M 0.000 description 1
- JMMWKPVZQRWMSS-UHFFFAOYSA-N isopropanol acetate Natural products CC(C)OC(C)=O JMMWKPVZQRWMSS-UHFFFAOYSA-N 0.000 description 1
- 229940011051 isopropyl acetate Drugs 0.000 description 1
- GWYFCOCPABKNJV-UHFFFAOYSA-N isovaleric acid Chemical compound CC(C)CC(O)=O GWYFCOCPABKNJV-UHFFFAOYSA-N 0.000 description 1
- OQAGVSWESNCJJT-UHFFFAOYSA-N isovaleric acid methyl ester Natural products COC(=O)CC(C)C OQAGVSWESNCJJT-UHFFFAOYSA-N 0.000 description 1
- 239000004922 lacquer Substances 0.000 description 1
- 239000002649 leather substitute Substances 0.000 description 1
- 229940115932 legionella pneumophila Drugs 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940017144 n-butyl lactate Drugs 0.000 description 1
- 229920005615 natural polymer Polymers 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- 229940049776 nobac Drugs 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940051027 pasteurella multocida Drugs 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 229940112041 peripherally acting muscle relaxants other quaternary ammonium compound in atc Drugs 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- ACVYVLVWPXVTIT-UHFFFAOYSA-M phosphinate Chemical compound [O-][PH2]=O ACVYVLVWPXVTIT-UHFFFAOYSA-M 0.000 description 1
- 229910052698 phosphorus Chemical group 0.000 description 1
- 239000011574 phosphorus Chemical group 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- 239000004999 plastisol Substances 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920002215 polytrimethylene terephthalate Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- SCUZVMOVTVSBLE-UHFFFAOYSA-N prop-2-enenitrile;styrene Chemical compound C=CC#N.C=CC1=CC=CC=C1 SCUZVMOVTVSBLE-UHFFFAOYSA-N 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 229940007042 proteus vulgaris Drugs 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 239000002964 rayon Substances 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- DCKVNWZUADLDEH-UHFFFAOYSA-N sec-butyl acetate Chemical compound CCC(C)OC(C)=O DCKVNWZUADLDEH-UHFFFAOYSA-N 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 229940007046 shigella dysenteriae Drugs 0.000 description 1
- 229940115939 shigella sonnei Drugs 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 238000004513 sizing Methods 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000002422 sporicide Substances 0.000 description 1
- 229940057981 stearalkonium chloride Drugs 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 239000000021 stimulant Substances 0.000 description 1
- 125000005017 substituted alkenyl group Chemical group 0.000 description 1
- 125000003107 substituted aryl group Chemical group 0.000 description 1
- 125000005346 substituted cycloalkyl group Chemical group 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Chemical group 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- 239000012209 synthetic fiber Substances 0.000 description 1
- 239000004758 synthetic textile Substances 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 229920005992 thermoplastic resin Polymers 0.000 description 1
- 239000011135 tin Substances 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 208000007089 vaccinia Diseases 0.000 description 1
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 description 1
- 229960003165 vancomycin Drugs 0.000 description 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- 239000002966 varnish Substances 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 230000003253 viricidal effect Effects 0.000 description 1
- 239000012873 virucide Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000002759 woven fabric Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/38—Cationic compounds
- C11D1/62—Quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/162—Organic compounds containing Si
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C11D3/373—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds containing silicones
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/43—Solvents
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Dispersion Chemistry (AREA)
- Toxicology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Description
ウイルス、例えば、HIV-1(AIDSウイルス)、B型肝炎ウイルス(HVB)、C型肝炎ウイルス(HCV)、アデノウイルス、単純ヘルペス、インフルエンザ、呼吸器合胞体ウイルス(RSV)、ワクシニア、トリインフルエンザウイルス、トリ気管支炎、仮性狂犬病ウイルス、イヌジステンパー、ニューカッスル病、風疹、トリポリオーマウイルス、ネコ白血病、ネコピコルナウイルス、感染性ウシ鼻気管炎、感染性気管支炎(トリIBV)、狂犬病、伝染性胃腸炎ウイルス、マレック病;
真菌、例えば、毛瘡白癬菌(Trichophyton mentagrophytes)、黒色アスペルギルス(Aspergillus niger)、カンジダアルビカンス(Candida albicans)、黄色アスペルギルス(Aspergillus flavus)、アスペルギルスフミガーツス(Aspergillus fumigatus)、トリコフィトンインテージギターレ(Trichophyton interdigitale)、アルテルナリアテニウス(Alternaria tenius)、フザリウムオキシスポルム(Fusarium oxysporum)、ゲオトリクムカンジドゥム(Geotrichum candidum)、ミドリカビ病菌(Penicillium digitatum)、フィトフロサインフェスタンス(Phytophthora infestans)、クロネ(Rhizopus nigricans)、トリコデルマハルジアヌム(Trichoderma harzianum)、トリコフィトンインテージギターレ(Trichophyton interdigitale);
細菌、例えば、緑膿菌(Pseudomonas aeruginosa)、黄色ブドウ球菌(Staphylococcus aureus)、ブタコレラ菌(Salmonella choleraesuis)、アシネトバクターバウマンニー(Acinetobacter baumannii)、ブレビバクテリウムアンモニアゲネス(Brevibacterium ammoniagenes)、カンピロバクタージェジュニ(Campylobacter jejuni)、エンテロバクターエロゲネス(Enterobacter aerogenes)、大腸菌(Escherichia coli)、肺炎かん菌(Klebsiella pneumoniae)、プロテウスミラビリス(Proteus mirabilis)、シュードモナスセパシア(Pseudomonas cepacia)、パラチフスB菌(Salmonella schottmuelleri)、腸チフス菌(Salmonella typhi)、鼠チフス菌(Salmonella typhimurium)、セラチアマルセッセンス(Serratia marcescens)、志賀赤痢菌(Shigella dysenteriae)、フレクスナー赤痢菌(Shigella flexneri)、ソンネ赤痢菌(Shigella sonnei)、表皮ブドウ球菌(Staphyloccus epidermidis)、大便連鎖球菌(Streptoccus faecalis)、大便連鎖球菌(Streptoccus faecalis)(バンコマイシン耐性)、化膿連鎖球菌(Streptococcus pyogenes)、ビブリオコレラ(Vibrio chlorae)、ザントモナスアクソノポジスpvシトリ(Xanthomonas axonopodis pv citri)(柑橘類潰瘍病)、アシネトバクターカルコアセチカス(Acinetobacter calcoaceticus)、気管支敗血症菌(Bordetella bronchiseptica)、オウム病クラミジア(Chlamydia psittaci)、エンテロバクタークロアカエ(Enterobacter cloacae)、エンテロコッカスフェカーリス(Enterococcus faecalis)、フソバクテリウムネクロフォールム(Fus
obacterium necrophorum)、レジオネラニューモフィラ(Legionella pneumophila)、リステリア菌(Listeria monocytogenes)、動物パスツレラ症病原菌(Pasteurella multocida)、プロテウスブルガリス(Proteus vulgaris)、腸炎菌(Salmonella enteritidis)、マイコプラズマガリセプティクム(Mycoplasma gallisepticum)、エルシニアエンテロコリチカ(Yersinia enterocolitica)、アエロモナスサルモニシダ(Aeromonas salmonicida)、シュードモナスプチダ(Pseudomonas putida)、ビブリオアングイラルム(Vibrio anguillarum)
が含まれる。
R'およびR"はそれぞれ、水素、C1〜C8アルキル、シクロアルキル、ヘテロシクリル、アリール、またはアリールアルキルであり、rは1〜6の整数であり、またはR'およびR"が一緒になって環状官能基を形成し、
アルキル、アルケニル、ヘテロシクリル、シクロアルキル、アリール、アルキルアリール、およびアリールアルキルに適用される「置換」という用語は、上述のFから-NR'SO2R"までの置換基を指す。
(CH3)n(A)mN+X-
を有するものであり、式中、Aは、R1、R2、R3、およびR4に関する上記の定義の通りであってよい。X-は、塩化物イオン、フッ化物イオン、臭化物イオン、またはヨウ化物イオン、およびスルホン酸イオンから選択され(好ましくは、塩化物イオンまたは臭化物イオン)、nは1〜3であり(好ましくは2または3)、mは1〜3であり(好ましくは1または2)、ただしnおよびmの合計は4である。好ましくは、Aは、C6〜20(例えば、C8〜18、即ち8、9、10、11、12、13、14、15、16、17、または18個の炭素原子を有し、またはC8〜12)置換もしくは非置換および/または直鎖もしくは分岐状および/または中断もしくは非中断アルキル、アリール、アルキルアリール、アリールアルキル、またはシクロアルキル基である(適切な置換基は、R1、R2、R3、およびR4に関する上記の定義の通りである。)。各基Aは、同じでも異なっていてもよい。
塩化セタルコニウム
塩化セチルピリジニウム
グリシジルトリメチルアンモニウムクロリド
塩化ステアラルコニウム
塩化ゼフィラン(R)
ハイアミン3500
ジイソブチルフェノキシエトキシエチルジメチルベンジルアンモニウムクロリド
ハイアミン1622(R)
塩化セタルコニウム
セチルジメチルベンジルアンモニウムクロリド
トリトンK12
セチルトリメチルアンモニウムクロリド
リターダーLA
1-ヘキサデシルピリジニウムクロリド
グリシジルトリメチルアンモニウムクロリド
塩化ベンゼトニウムCAS 121-54-0
塩化セタルコニウムCAS 122-18-9
セトリミドCAS 8044-71-1
塩化セチルピリジニウム(無水物)CAS 123-03-5
塩化セテアラルコニウムCAS 122-19-0
臭化セトリモニウムCAS 57-09-0
1.大腸菌K12 OラフH48を用いる懸濁試験を用いた殺菌活性の評価
この試験の狙いは、大腸菌K12 OラフH48に対する本発明の生成物の殺菌活性を評価することである。
大腸菌K12 OラフH48
試験生物は、4℃にてLBAプレート上で維持した。1つのコロニーを用いて、100mlのフラスコのLBに接種し、37℃にて16時間インキュベートして、定常期に到達した。対数期の培養について、4mlのLBに1つのコロニーを接種し、37℃にて16時間インキュベートした。1mlの細菌懸濁物を、次いで、100mlのLBに加えて、およそ0.375のOD600まで成長させた。それぞれの生物を、LBを用いて系列希釈し、LBAプレート上で培養して、1mlあたりのコロニー形成単位数を決定した。
1.選択された実験条件の妥当性確認
1mlのウシアルブミン溶液(BSA)を、およそ3.0×108cfu/mlを含有する1mlの細菌試験懸濁物と共に試験管に入れ、20℃の試験温度にて2分間インキュベートした。この時間の最後に、8mlのLBを加えた。この混合物を、10分間の試験接触時間でインキュベートした。次いで、溶液を、3.0×103および3.0×102cfu/mlに希釈した。0.1mlのこれらの試験溶液を、3重にピペットで分注し、12〜15mlのLBA上で培養したが、これは3.0×102および3.0×101cfuに等しい。プレートを37℃にて24時間インキュベートした。
9mlの中和剤(NF)を試験管に入れ、およそ3.0×108cfu/mlを含有する1mlの細菌懸濁物と混合した。混合物を20℃にて10分間インキュベートした。懸濁物を3.0×103および3.0×102cfu/mlにLBAを用いて希釈した。0.1mlを、次いで、12〜15mlのLBAを含有する3重のプレートにピペットで分注した。プレートを37℃にて24時間インキュベートした。
1mlのウシアルブミン溶液(BSA)を、1mlのLBと共に試験管に入れ、20℃にて5分間インキュベートした。次いで、1mlをとって、8mlの中和剤(NF)に加えた。5分間のインキュベーションの後に、1mlの細菌懸濁物を加えた。混合物を20℃にて10分間放置した。懸濁物を3.0×103および3.0×102cfu/mlにLBを用いて希釈し、次いで、0.1mlを3重で12〜15mlのLBA上で培養した。プレートを37℃にて24時間インキュベートした。
試験のために選択した条件は:
温度:20℃
接触時間:2分間
干渉物質:ウシアルブミン溶液(0.3%)
生成物試験溶液:Byotrol生成物G5(0.5%(v/v)、飲用水で希釈)と、記載される界面活性剤/界面活性剤混合物、pHは記載するようにして調整する
である。
この試験の狙いは、典型的な家庭の条件下での大腸菌K12 OラフH48に対する本発明の生成物の残存効力を評価することである。
大腸菌K12 OラフH48
試験生物は、4℃にてLBAプレート上で維持した。1つのコロニーを用いて、100mlのフラスコのLBに接種し、37℃にて16時間インキュベートして、定常期に到達した。対数期の培養について、4mlのLBに1つのコロニーを接種し、37℃にて16時間インキュベートした。1mlの細菌懸濁物を、次いで、100mlのLBに加えて、およそ0.375のOD600まで成長させた。それぞれの生物を、次いで、LBを用いて系列希釈し、LBAプレート上で培養して、1mlあたりのコロニー形成単位数を決定した。
1.選択された実験条件の妥当性確認
1mlのウシアルブミン溶液(BSA)を、およそ3.0×108cfu/mlを含有する1mlの細菌試験懸濁物と共に試験管に入れ、20℃の試験温度にて2分間インキュベートした。この時間の最後に、8mlのLBを加えた。この混合物を、10分間の試験接触時間でインキュベートした。次いで、溶液を、3.0×103および3.0×102cfu/mlに希釈した。0.1mlのこれらの試験溶液を、3重にピペットで分注し、12〜15mlのLBA上で培養したが、これは3.0×102および3.0×101cfuに等しい。プレートを37℃にて24時間インキュベートした。
9mlの中和剤(NF)を試験管に入れ、およそ3.0×108cfu/mlを含有する1mlの細菌懸濁物と混合した。混合物を20℃にて10分間インキュベートした。懸濁物を3.0×103および3.0×102cfu/mlにLBAを用いて希釈した。0.1mlを、次いで、12〜15mlのLBAを含有する3重のプレートにピペットで分注した。プレートを37℃にて24時間インキュベートした。
1mlのウシアルブミン溶液(BSA)を、1mlのLBと共に試験管に入れ、20℃にて5分間インキュベートした。次いで、1mlをとって、8mlの中和剤(NF)に加えた。5分間のインキュベーションの後に、1mlの細菌懸濁物を加えた。混合物を20℃にて10分間放置した。懸濁物を3.0×103および3.0×102cfu/mlにLBを用いて希釈し、次いで、0.1mlを3重で12〜15mlのLBA上で培養した。プレートを37℃にて24時間インキュベートした。
1.担体の前処理
担体を、イソプロパノール(70%v/v)を用いて噴霧により清浄/消毒した。過剰のイソプロパノールを用いて、表面全体を完全に被覆した。過剰のイソプロパノールを流すことにより除去した。さらなる乾燥を10分間可能にした。
タイル表面への約106CFUの細菌の1回目の攻撃。塗布容量は、10μLに設定する。イソプロパノールの残存量が残っていると、塗布された細菌のいくらかは死滅する可能性がある。10μLの塗布容量を、滅菌プラスチックスパチュラ(ドリガルスキースパチュラ)によりタイル表面全体に広げた。攻撃されたタイルを、50分間にわたって乾燥させた。
1mLの消毒生成物を、前処理した担体表面に塗布した。塗布した消毒生成物を、滅菌プラスチックスパチュラ(ドリガルスキースパチュラ)により表面全体に広げた。過剰の消毒生成物による表面処理を、10分間にわたって行った。前処理した担体を、プロフェッショナルケアワイプで覆って、清潔な場所に一晩保管した。
タイル表面への接種は、約106CFUの細菌を用いることにより行った。塗布容量は、10μLに設定した。イソプロパノールの残存量が残っていると、塗布された細菌のいくらかは死滅する可能性がある。10μLの塗布容量を、滅菌プラスチックスパチュラ(ドリガルスキースパチュラ)によりタイル表面全体に広げた。攻撃されたタイルを、50分間にわたって乾燥させた。
タイル表面を、10mLの滅菌水(水ミリポア処理)ですすいだ。すすぎの後に、タイルを1時間までまたは表面が目視で乾燥するまで乾燥させた。
摩耗サイクルを研磨ステップとして用いる。乾燥摩耗サイクルは、プロフェッショナルケアワイプで包んだコルク片を前後に動かすことにより行った。通常の手の圧力を印加する。非ビスコース型のプロフェッショナルケアワイプは、クアットまたはPHMBを吸着しない。
プロフェッショナルケアワイプの湿潤化は、水ミリポア処理をワイプ上に噴霧することにより行った。噴霧は、約30cmから1回吹きかけることにより行った。湿潤摩耗サイクルを、研磨ステップとして用いた。湿潤摩耗サイクルは、湿潤(水ミリポア処理)プロフェッショナルケアワイプで包んだコルク片を前後に動かすことにより行った。通常の手の圧力を印加した。湿潤表面を、少なくとも10分間乾燥させた。
タイルを、約106CFUの細菌で攻撃する。塗布容量は、10μLに設定した。塗布容量を、滅菌プラスチックスパチュラ(ドリガルスキースパチュラ)によりタイル表面全体に広げた。攻撃されたタイルを、5〜10分間にわたって乾燥させた。生存細菌を、500μLのLB+NFを塗布することにより溶解した。塗布したLB+NFを、滅菌プラスチックスパチュラ(ドリガルスキースパチュラ、使い捨て用)によりタイル表面全体に広げた。中和剤は、生存細菌を死滅させる効果はなかったが、タイル上の消毒生成物を不活性化する。生存細菌を溶解するために、タイルを室温にて30分間インキュベートした。溶解した生存細菌を、滅菌プラスチックスパチュラ(ドリガルスキースパチュラ)により回収した。
回収した液体から、滅菌ピペットにより標本を採取した。100μLの試料を900μLのLB+NFに加えた。LB+NF中で10-4の100μL試料までの系列希釈を行い、希釈物を寒天プレートに移す。
以下は、本発明による抗菌組成物の代表である。
以下の表に示す組成物を水で希釈して、0.01%の組成物(E4LまたはE52またはE8LまたはE10L)および99.99%の水を含む溶液を得た。
Claims (16)
- (i)少なくとも1種の下式:
(ii)式(H3C)[SiO(CH3)2]nSi(CH3)3または式(H3C)[SiO(CH3)H]nSi(CH3)3を有するシロキサンあるいはこれらの混合物(式中、nは1〜8である。)から選択され、20℃大気圧で0.5〜5センチストークの粘度を有するシロキサンと、
(iii)極性溶媒と、
(iv)ポリマービグアニジン、イソチアザロン、オルトフェニルフェノール、ニトロブロモプロパン、および重合化第四級アンモニウム化合物、あるいはこれらの混合物から選択される少なくとも1種の追加の抗菌剤と、
を含み、
前記成分(i)と(ii)の分子数の比が100:1〜5:1であり、表面に適用すると、表面上または表面での微生物コロニーの形成を実質的に低減または制御するように働く抗菌組成物。 - 前記成分(i)と(ii)の分子数の比が70:1〜20:1である、請求項1に記載の組成物。
- 前記第四級アンモニウム化合物が、ベンジルジメチル-n-テトラデシル-アンモニウムクロリド、ベンジルジメチル-n-ドデシル-アンモニウムクロリド、n-ドデシル-n-テトラデシルジメチル-アンモニウムクロリド、ベンジル-C12〜C16-アルキル-ジメチル-アンモニウムクロリド、ベンジル-ココアルキル-ジメチル-アンモニウムクロリド、およびジ-n-デシルジメチルアンモニウムクロリドから選択される、請求項1または2に記載の組成物。
- 前記成分(i)が、オクチルデシルジメチルアンモニウムクロリド、ジオクチルジメチルアンモニウムクロリド、ジデシルジメチルアンモニウムクロリド、およびアルキルジメチルベンジルアンモニウムクロリドからなる、請求項1に記載の抗菌組成物。
- 前記シロキサンが、20℃大気圧で2g/100ml水未満の水溶解度を有する、請求項1から4のいずれかに記載の組成物。
- 前記シロキサンが、ヘキサメチルジシロキサン、オクタメチルトリシロキサン、デカメチルテトラシロキサン、ドデカメチルペントラシロキサン、およびこれらの混合物から選択される、請求項1から5のいずれか一項に記載の組成物。
- 前記極性溶媒が、水、エタノール、n-プロパノール、イソプロパノール、ジエチレングリコール、ジプロピレングリコール、およびこれらの混合物から選択される、請求項1から6のいずれか一項に記載の組成物。
- 追加の抗菌剤がポリヘキサメチレンビグアニジンである、請求項1から7のいずれか一項に記載の組成物。
- 前記成分(i)と成分(iv)の分子数の比が、8:1〜15:1である、請求項8に記載の組成物。
- 前記成分(ii)のすべての分子に対する抗菌成分(i)および(iv)(存在する場合)の分子の総数の比が、5:1〜80:1である、請求項1から9のいずれか一項に記載の組成物。
- 成分(i)および(iv)の全濃度が30ppm以上400ppm未満であると抗菌効果を発揮する、請求項1から10のいずれか一項に記載の組成物。
- (A)(i)請求項1または4に規定する第四級アンモニウム化合物である成分(i)と、(ii)請求項1、5、および6のいずれか一項に規定するシロキサンとを一緒に混合するステップ、(B)(A)で形成された混合物に(iii)極性溶媒を添加するステップ、および(C)得られた混合物を、透明溶液が形成されるまでかき混ぜるステップを含む、請求項1から11のいずれか一項に記載の組成物を調製する方法。
- ステップ(A)において、成分(ii)を極性溶媒中の成分(i)の濃縮溶液と混合し、任意選択でステップ(A)、(B)、および/またはステップ(C)において、少なくとも1種の追加の抗菌剤を添加するステップをさらに含む、請求項12に記載の方法。
- 表面上または表面での微生物コロニーの形成を実質的に低減または制御する、請求項1から11のいずれか一項に記載の組成物の使用。
- 請求項1から11のいずれか一項に記載の組成物を表面に適用することを含む、表面上または表面での微生物コロニーの形成を実質的に低減または制御し、表面上または表面での低減または制御の残留効果をもたらす方法。
- 請求項1から11のいずれか一項に記載の組成物を表面に適用することを含む、微生物の表面への接着および付着を防止し、または表面に接着し付着する微生物の数を低減する方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0713799.5A GB0713799D0 (en) | 2007-07-17 | 2007-07-17 | Anti-microbial compositions |
GB0713799.5 | 2007-07-17 | ||
PCT/GB2008/002436 WO2009010749A2 (en) | 2007-07-17 | 2008-07-17 | Anti-microbial composition |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2010533691A JP2010533691A (ja) | 2010-10-28 |
JP2010533691A5 JP2010533691A5 (ja) | 2011-09-01 |
JP5631735B2 true JP5631735B2 (ja) | 2014-11-26 |
Family
ID=38461667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010516568A Expired - Fee Related JP5631735B2 (ja) | 2007-07-17 | 2008-07-17 | 抗菌組成物 |
Country Status (11)
Country | Link |
---|---|
US (2) | US8178484B2 (ja) |
EP (1) | EP2179019B1 (ja) |
JP (1) | JP5631735B2 (ja) |
CN (1) | CN101802159B (ja) |
AU (1) | AU2008277406B2 (ja) |
BR (1) | BRPI0814611A2 (ja) |
CA (1) | CA2693147C (ja) |
GB (2) | GB0713799D0 (ja) |
MX (1) | MX2010000694A (ja) |
WO (1) | WO2009010749A2 (ja) |
ZA (1) | ZA201000675B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20210093692A (ko) * | 2020-01-20 | 2021-07-28 | 김태근 | 악기용 인조가죽편 |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0713799D0 (en) | 2007-07-17 | 2007-08-22 | Byotrol Llc | Anti-microbial compositions |
JP5615708B2 (ja) * | 2007-09-17 | 2014-10-29 | バイオトロル・ピーエルシー | 抗微生物組成物を含む製剤 |
JP5255495B2 (ja) * | 2009-03-19 | 2013-08-07 | ディバーシー株式会社 | 殺カリシウイルス剤組成物およびその使用方法 |
US20130065071A1 (en) * | 2010-05-18 | 2013-03-14 | Dow Global Technologies Llc | Multilayer sheet, a thermoformed article, and a method for making the same |
WO2012041658A1 (en) | 2010-09-28 | 2012-04-05 | Unilever Nv | Aqueous rinse treatment compositions |
WO2012080918A2 (en) | 2010-12-14 | 2012-06-21 | Ecolab Usa Inc. | Wear resistant antimicrobial compositions and methods of use |
JP5980479B2 (ja) * | 2011-03-31 | 2016-08-31 | 小林製薬株式会社 | バイオフィルム除去用組成物 |
GB201118673D0 (en) * | 2011-10-28 | 2011-12-14 | Byotrol Plc | Anti-microbial composition |
US9532568B2 (en) * | 2013-01-22 | 2017-01-03 | Miraculum, Inc. | Product for mold prevention and treatment |
US20140206767A1 (en) * | 2013-01-22 | 2014-07-24 | Miraculum Applications AB | Product for mold prevention and treatment |
US9999633B2 (en) | 2013-04-09 | 2018-06-19 | International Business Machines Corporation | Antimicrobial cationic polycarbonates |
US9357772B2 (en) | 2013-04-09 | 2016-06-07 | International Business Machines Corporation | Antimicrobial cationic polycarbonates |
GB2515473A (en) | 2013-06-18 | 2014-12-31 | Robert Timothy Gros | Anti microbial inks and sealants |
GB2517778B (en) * | 2013-09-02 | 2015-08-05 | Robert Anthony William Scoones | Cleaning liquid |
US20150099010A1 (en) | 2013-10-07 | 2015-04-09 | Reoxcyn Discoveries Group, Inc | Redox signaling gel formulation |
US10206525B2 (en) | 2014-10-24 | 2019-02-19 | Leer, Inc. | Ice merchandiser with on-product financial payment system |
US10834922B2 (en) | 2014-11-26 | 2020-11-17 | Microban Products Company | Surface disinfectant with residual biocidal property |
US11033023B2 (en) | 2014-11-26 | 2021-06-15 | Microban Products Company | Surface disinfectant with residual biocidal property |
US10925281B2 (en) | 2014-11-26 | 2021-02-23 | Microban Products Company | Surface disinfectant with residual biocidal property |
US10842147B2 (en) | 2014-11-26 | 2020-11-24 | Microban Products Company | Surface disinfectant with residual biocidal property |
US10485827B2 (en) | 2016-01-19 | 2019-11-26 | Rdg Holdings, Inc. | Topical eye serum compositions, methods or preparing, and methods of use |
US11857674B2 (en) | 2016-05-18 | 2024-01-02 | Reoxcyn, Llc | Lubricant formulations |
US9474768B1 (en) | 2016-05-18 | 2016-10-25 | Reoxcyn Discoveries Group, Inc. | Lubricant formulations |
US11503824B2 (en) | 2016-05-23 | 2022-11-22 | Microban Products Company | Touch screen cleaning and protectant composition |
US9833471B1 (en) * | 2016-09-15 | 2017-12-05 | Reoxcyn Discoveries Group, Inc. | Hypochlorous acid-based hand sanitizer |
SG11201912534SA (en) * | 2017-06-28 | 2020-01-30 | Collidion Inc | Compositions, methods and uses for cleaning, disinfecting and/or sterilizing |
US10967082B2 (en) | 2017-11-08 | 2021-04-06 | Parasol Medical, Llc | Method of limiting the spread of norovirus within a cruise ship |
WO2019145959A1 (en) * | 2018-01-28 | 2019-08-01 | Hilico Off Grid Solutions Ltd. | System for accumulating rain water |
US10864058B2 (en) | 2018-03-28 | 2020-12-15 | Parasol Medical, Llc | Antimicrobial treatment for a surgical headlamp system |
US11401383B2 (en) * | 2018-04-20 | 2022-08-02 | Ecp Incorporated | Vehicle exterior protective coating |
US20200071540A1 (en) * | 2018-09-04 | 2020-03-05 | Parasol Medical LLC | Antimicrobial coating applied to protective body equipment such as helmets, shoulder pads, and elbow pads |
GB201919234D0 (en) * | 2019-12-23 | 2020-02-05 | Jvs Products Ltd | Compositions |
CN112868659B (zh) * | 2021-02-03 | 2022-03-11 | 3M中国有限公司 | 一种可施加于用户设备中的组合物及其用途 |
WO2023145559A1 (ja) * | 2022-01-31 | 2023-08-03 | 花王株式会社 | ウイルス又は菌を不活化する方法 |
Family Cites Families (96)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB991597A (en) | 1960-05-25 | 1965-05-12 | Wallace Cameron & Co Ltd | Improvements in or relating to detergent solutions |
US3697644A (en) * | 1966-10-18 | 1972-10-10 | Gillette Co | Cosmetic composition |
GB1460279A (en) * | 1973-05-10 | 1976-12-31 | Ici Ltd | Biocidal compositions |
US4173643A (en) * | 1973-12-20 | 1979-11-06 | Rohm And Haas Company | Synergistic microbiocidal compositions |
CA1087955A (en) | 1976-01-12 | 1980-10-21 | Phillip E. Sokol | Cleansing-sanitizing composition |
US4540505A (en) * | 1981-05-22 | 1985-09-10 | American Cyanamid Company | Disinfectant spray cleanser containing glycol ethers |
US4698148A (en) * | 1981-06-17 | 1987-10-06 | James Keane | Removal of chlorine-based contaminants from materials contaminated the same |
CA1212332A (en) | 1981-07-29 | 1986-10-07 | Julius Wagman | Hair conditioning compositions containing volatile silicone |
JPS607000B2 (ja) | 1982-10-20 | 1985-02-21 | 次郎 藤増 | 薬品処理拭掃除具用組成物及び拭掃除具 |
US4631273A (en) | 1984-11-05 | 1986-12-23 | Dow Corning Corporation | Aqueous emulsions using cationic silanes |
JPS61148285A (ja) | 1984-12-21 | 1986-07-05 | Toray Silicone Co Ltd | 固体材料処理剤組成物 |
JPH0672081B2 (ja) | 1985-06-07 | 1994-09-14 | 三菱瓦斯化学株式会社 | 植物生長促進剤 |
US4637890A (en) * | 1986-01-23 | 1987-01-20 | The Procter & Gamble Company | Detergent composition providing rinse cycle suds and turbidity control containing a soap, quaternary ammonium salt and a silicone |
JPH064761B2 (ja) * | 1986-03-19 | 1994-01-19 | 東亜道路工業株式会社 | アスフアルト・ポリオ−ル乳化物およびその製造方法 |
GB2188653A (en) * | 1986-04-02 | 1987-10-07 | Procter & Gamble | Biodegradable fabric softeners |
US4718941A (en) * | 1986-06-17 | 1988-01-12 | The Regents Of The University Of California | Infiltration processing of boron carbide-, boron-, and boride-reactive metal cermets |
US4788176A (en) * | 1986-12-29 | 1988-11-29 | Aluminum Company Of America | Adsorbent comprising metal oxide/hydroxide particles reacted with one or more phosphorous-containing materials having selected organic radicals attached thereto |
US5178495A (en) * | 1987-07-24 | 1993-01-12 | Reef Industries, Inc. | Polymeric film with biocide |
DE3739711A1 (de) * | 1987-11-24 | 1989-06-08 | Kreussler Chem Fab | Verwendung von polydialkylcyclosiloxanen als loesemittel fuer die chemischreinigung |
GB8804555D0 (en) * | 1988-02-26 | 1988-03-30 | Procter & Gamble | Imidazole compounds & textile treatment compositions containing them |
US5869172A (en) * | 1988-03-14 | 1999-02-09 | Nextec Applications, Inc. | Internally-coated porous webs with controlled positioning of modifiers therein |
US5856245A (en) * | 1988-03-14 | 1999-01-05 | Nextec Applications, Inc. | Articles of barrier webs |
US5874164A (en) * | 1988-03-14 | 1999-02-23 | Nextec Applications, Inc. | Barrier webs having bioactive surfaces |
US4822511A (en) | 1988-05-06 | 1989-04-18 | Rohm And Haas Company | Preservative compositions comprising a synergistic mixture of isothiagolones |
US5196029A (en) * | 1989-04-24 | 1993-03-23 | Kao Corporation | Hair-treatment composition, bleaching composition and hair color tone modifier composition |
EP0398137A3 (en) * | 1989-05-19 | 1991-11-21 | The Procter & Gamble Company | Rinse-added fabric conditioning compositions containing fabric softening agents and cationic polyester soil release polymers |
US4954335A (en) * | 1989-05-31 | 1990-09-04 | Helene Curtis, Inc. | Clear conditioning composition and method to impart improved properties to the hair |
US4976956A (en) * | 1989-07-24 | 1990-12-11 | Helene Curtis, Inc. | Method and composition to impart improved conditioning properties to the hair |
WO1991007090A1 (de) | 1989-11-16 | 1991-05-30 | Henkel Kommanditgesellschaft Auf Aktien | Bekämpfung von schleimbildenden mikroorganismen |
US5529690A (en) * | 1990-07-18 | 1996-06-25 | The Australian National University | Formation of porous materials |
GB9018654D0 (en) | 1990-08-24 | 1990-10-10 | Reckitt & Colmann Prod Ltd | Method of disinfection |
JP2820329B2 (ja) * | 1991-04-01 | 1998-11-05 | 株式会社資生堂 | 毛髪化粧料 |
IT1247918B (it) | 1991-05-10 | 1995-01-05 | Germo Spa | Composizioni disinfettanti polivalenti |
DE69201565T2 (de) | 1991-06-07 | 1995-09-21 | Minnesota Mining & Mfg | Desinfizierende shampoozusammensetzung für tiere. |
US5326492A (en) | 1991-11-18 | 1994-07-05 | Medical Polymers, Inc. | Disinfectant mixture containing water soluble lubricating and cleaning agents and method |
US5244666A (en) * | 1992-02-04 | 1993-09-14 | Consolidated Chemical, Inc. | Presurgical skin scrub and disinfectant |
CA2134640C (en) * | 1992-05-12 | 1998-11-03 | Ellen Schmidt Baker | Concentrated fabric softener compositions containing biodegradable fabric softeners |
US5538667A (en) * | 1993-10-28 | 1996-07-23 | Whitehill Oral Technologies, Inc. | Ultramulsions |
JPH07179890A (ja) * | 1993-12-24 | 1995-07-18 | Olympus Optical Co Ltd | 光学部品用手拭き仕上げ液 |
US5753214A (en) * | 1994-08-24 | 1998-05-19 | Seiwa Kasei Co., Ltd. | Base material for cosmetics and uses of the same |
US5834114A (en) * | 1995-05-31 | 1998-11-10 | The Board Of Trustees Of The University Of Illinois | Coated absorbent fibers |
US5645841A (en) * | 1995-06-05 | 1997-07-08 | Whitehill Oral Technologies, Inc. | Ultramulsion based oral care rinse compositions |
US5711936A (en) * | 1995-06-05 | 1998-01-27 | Whitehill Oral Technologies, Inc. | Ultramulsion based ingestible compositions |
US5733536A (en) * | 1995-06-05 | 1998-03-31 | Whitehill Oral Technologies, Inc. | Ultramulsion based hair care compositions |
US5733529A (en) * | 1995-06-05 | 1998-03-31 | Whitehill Oral Technologies, Inc. | Ultramulsion based antigingivitis toothpaste compositions |
US5665374A (en) * | 1995-06-05 | 1997-09-09 | Whitehill Oral Technologies, Inc. | Ultramulsion containing interdental delivery devices |
AU6155696A (en) | 1995-06-05 | 1996-12-24 | Whitehill Oral Technologies, Inc. | Ultramulsion based paint and coating products |
US5730967A (en) * | 1995-06-05 | 1998-03-24 | Whitehill Oral Technologies, Inc. | Ultramulsion based skin care compositions |
US5651959A (en) * | 1995-06-05 | 1997-07-29 | Whitehill Oral Technologies, Inc. | Ultramulsion based oral care compositions |
GB2304111A (en) * | 1995-08-04 | 1997-03-12 | Reckitt & Colman Inc | Pine oil cleaning composition |
US5688449A (en) * | 1995-10-02 | 1997-11-18 | Nitech Corporation | Method of forming and extruding an additive-coated resin composition |
US5681637A (en) * | 1996-02-01 | 1997-10-28 | Aller-Gard 100 Products, Inc. | Microorganism resistant pile weatherstripping |
US5670055A (en) * | 1996-08-08 | 1997-09-23 | Nalco Chemical Company | Use of the linear alkylbenzene sulfonate as a biofouling control agent |
US5830447A (en) * | 1996-09-04 | 1998-11-03 | The Procter & Gamble Company | Personal care compositions |
US6039965A (en) * | 1996-09-27 | 2000-03-21 | Calgon Corporation | Surfanctants for reducing bacterial adhesion onto surfaces |
US6080706A (en) * | 1996-10-11 | 2000-06-27 | Colgate Palmolive Company | All Purpose liquid cleaning compositions |
US5869071A (en) * | 1996-11-07 | 1999-02-09 | B & G Labs, Inc. | One-step skin cleaning composition and skin treatment method for incontinent dermatitis |
GB2320927B (en) * | 1997-01-06 | 2001-04-18 | Reckitt & Colman Inc | Germicidal hard surface cleaner |
JPH10195032A (ja) * | 1997-01-08 | 1998-07-28 | Earth Chem Corp Ltd | 第四級アンモニウム塩水溶液の粘度調整方法および該水溶液の粘度調整剤 |
GR1002937B (el) | 1997-02-14 | 1998-07-13 | Νεα πολυδυναμη χημικη συνθεση πολλαπλων εφαρμογων και μεθοδος παρασκευης της | |
US6656923B1 (en) * | 1997-06-09 | 2003-12-02 | The Procter & Gamble Company | Uncomplexed cyclodextrin compositions for odor and wrinkle control |
US5955093A (en) * | 1997-06-09 | 1999-09-21 | The Procter & Gamble Company | Uncomplexed cyclodextrin compositions for odor control |
CO5040174A1 (es) * | 1997-12-12 | 2001-05-29 | Colgate Palmolive Co | Composiciones antimicrobianas para multiples propositos en microemulsion que contienen un tensioactivo cationico |
JPH11278589A (ja) | 1998-03-25 | 1999-10-12 | Onoe Kikai:Kk | タンク排出装置 |
JP4167751B2 (ja) * | 1998-03-31 | 2008-10-22 | 大日本除蟲菊株式会社 | 防カビ剤 |
US6107268A (en) * | 1999-04-16 | 2000-08-22 | Kimberly-Clark Worldwide, Inc. | Sorbent material |
US6159483A (en) | 1998-06-01 | 2000-12-12 | Colgate-Palmolive Company | Stabilized liquid aqueous composition |
GB2338651A (en) | 1998-06-27 | 1999-12-29 | Woollard Trevor P | Liquid polymer composition |
US6096702A (en) | 1998-10-01 | 2000-08-01 | Imaginative Research Associates, Inc. | Post foaming clear gels and solutions |
TW374095B (en) * | 1998-10-07 | 1999-11-11 | Dow Corning Taiwan Inc | A process for cleaning textile |
US6013683A (en) * | 1998-12-17 | 2000-01-11 | Dow Corning Corporation | Single phase silicone and water compositions |
JP3558907B2 (ja) | 1998-12-28 | 2004-08-25 | ライオン株式会社 | 硬表面防汚抗菌洗浄剤組成物 |
GB9901702D0 (en) | 1999-01-27 | 1999-03-17 | Reckitt & Colman Inc | Improvements in or relating to organic compositions |
US6187327B1 (en) | 1999-05-19 | 2001-02-13 | Kevin Stack | Antimicrobial sanitizing lotion with skin protection properties |
AR029170A1 (es) | 1999-06-29 | 2003-06-18 | Colgate Palmolive Co | Una composicion de limpieza en forma de microemulsion antimicrobiana para fines multiples |
KR20010017103A (ko) | 1999-08-07 | 2001-03-05 | 후버 리차드 에이치. | 직물의 세탁방법 |
DE19945503A1 (de) | 1999-09-23 | 2001-04-05 | Henkel Kgaa | Mehrphasiges Reinigungsmittel mit antimikrobieller Wirkung |
KR20030008206A (ko) * | 1999-10-22 | 2003-01-24 | 더 프록터 앤드 갬블 캄파니 | 신발 처리용 조성물, 이의 사용 방법 및 이를 사용한 제품 |
GB9929972D0 (en) * | 1999-12-17 | 2000-02-09 | Unilever Plc | Hair treatment composition |
GB2374011C (en) | 2001-01-04 | 2008-02-06 | Byotrol Llc | Anti-microbial composition |
CN1302707C (zh) * | 2001-01-04 | 2007-03-07 | 拜奥特罗尔股份有限公司 | 抗微生物组合物 |
US6821943B2 (en) | 2001-03-13 | 2004-11-23 | S. C. Johnson & Son, Inc. | Hard surface antimicrobial cleaner with residual antimicrobial effect comprising an organosilane |
GB0121804D0 (en) * | 2001-09-10 | 2001-10-31 | Unilever Plc | Fabric conditioning compositions |
DE10147186A1 (de) * | 2001-09-25 | 2003-04-24 | Beiersdorf Ag | Wirkstoffkombinationen aus Polyhexamethylenbiguanid-Hydrochlorid und Distearyldimethylammoniumchlorid und Zubereitungen, solche Wirkstoffkombinationen enthaltend |
US6846846B2 (en) * | 2001-10-23 | 2005-01-25 | The Trustees Of Columbia University In The City Of New York | Gentle-acting skin disinfectants |
US7745425B2 (en) * | 2002-02-07 | 2010-06-29 | The Trustees Of Columbia University In The City Of New York | Non-irritating compositions containing zinc salts |
GB0212157D0 (en) * | 2002-05-27 | 2002-07-03 | Unilever Plc | Fabric conditioning composition |
CN100594878C (zh) * | 2004-03-31 | 2010-03-24 | 信越化学工业株式会社 | 含有硅氧烷聚合物的化妆品 |
CN100593028C (zh) * | 2004-07-07 | 2010-03-03 | 陶氏康宁公司 | 通过乳液聚合生产的有机基聚硅氧烷树脂的乳液 |
US20090069436A1 (en) * | 2004-08-05 | 2009-03-12 | Ebiox, Ltd. | Antimicrobial skin composition comprising a biguanide or a quaternium compound |
JP4680606B2 (ja) * | 2005-01-07 | 2011-05-11 | 大日本除蟲菊株式会社 | 水系防カビ剤 |
TW200640535A (en) * | 2005-02-07 | 2006-12-01 | Showa Denko Kk | Hair relaxer |
US7896795B2 (en) | 2005-10-25 | 2011-03-01 | Goss International Americas, Inc. | Folder with signature support |
US20070141126A1 (en) * | 2005-12-21 | 2007-06-21 | Hudson Tammy M | Germicidal surface-covering assembly |
GB0713799D0 (en) | 2007-07-17 | 2007-08-22 | Byotrol Llc | Anti-microbial compositions |
JP5615708B2 (ja) * | 2007-09-17 | 2014-10-29 | バイオトロル・ピーエルシー | 抗微生物組成物を含む製剤 |
-
2007
- 2007-07-17 GB GBGB0713799.5A patent/GB0713799D0/en not_active Ceased
-
2008
- 2008-07-17 EP EP08775967.6A patent/EP2179019B1/en not_active Not-in-force
- 2008-07-17 AU AU2008277406A patent/AU2008277406B2/en not_active Ceased
- 2008-07-17 US US12/669,415 patent/US8178484B2/en active Active
- 2008-07-17 BR BRPI0814611-0A2A patent/BRPI0814611A2/pt active IP Right Grant
- 2008-07-17 JP JP2010516568A patent/JP5631735B2/ja not_active Expired - Fee Related
- 2008-07-17 WO PCT/GB2008/002436 patent/WO2009010749A2/en active Application Filing
- 2008-07-17 CA CA2693147A patent/CA2693147C/en active Active
- 2008-07-17 MX MX2010000694A patent/MX2010000694A/es active IP Right Grant
- 2008-07-17 CN CN200880107233.4A patent/CN101802159B/zh not_active Expired - Fee Related
- 2008-07-17 GB GB0813099A patent/GB2457322C/en not_active Expired - Fee Related
-
2010
- 2010-01-28 ZA ZA2010/00675A patent/ZA201000675B/en unknown
-
2011
- 2011-10-26 US US13/281,707 patent/US8575085B2/en active Active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20210093692A (ko) * | 2020-01-20 | 2021-07-28 | 김태근 | 악기용 인조가죽편 |
KR102322022B1 (ko) * | 2020-01-20 | 2021-11-04 | 김태근 | 악기용 인조가죽편 |
Also Published As
Publication number | Publication date |
---|---|
CN101802159A (zh) | 2010-08-11 |
US20120071525A1 (en) | 2012-03-22 |
US8178484B2 (en) | 2012-05-15 |
WO2009010749A2 (en) | 2009-01-22 |
AU2008277406A1 (en) | 2009-01-22 |
GB2457322B (en) | 2010-06-16 |
EP2179019B1 (en) | 2016-12-14 |
GB0713799D0 (en) | 2007-08-22 |
JP2010533691A (ja) | 2010-10-28 |
US8575085B2 (en) | 2013-11-05 |
EP2179019A2 (en) | 2010-04-28 |
CN101802159B (zh) | 2013-03-27 |
AU2008277406B2 (en) | 2013-06-06 |
BRPI0814611A2 (pt) | 2015-01-27 |
CA2693147C (en) | 2016-08-16 |
US20100197748A1 (en) | 2010-08-05 |
ZA201000675B (en) | 2011-07-27 |
CA2693147A1 (en) | 2009-01-22 |
GB2457322C (en) | 2011-10-26 |
GB0813099D0 (en) | 2008-08-27 |
WO2009010749A3 (en) | 2009-04-02 |
AU2008277406A2 (en) | 2010-03-25 |
MX2010000694A (es) | 2010-06-25 |
GB2457322A (en) | 2009-08-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5631735B2 (ja) | 抗菌組成物 | |
CA2699696C (en) | Anti-microbial compositions comprising a non-ionic surfactant | |
AU2002216292B2 (en) | Anti-microbial composition | |
GB2475790A (en) | Anti-microbial wipe | |
AU2002216292A1 (en) | Anti-microbial composition | |
WO2010043863A2 (en) | Anti-microbial composition | |
EP2107948A2 (en) | Stable aqueous solutions of silane quat ammonium compounds | |
GB2374011A (en) | Anti-microbial composition comprising anti-microbial agent, polar solvent & surface orientating surfactant such as polysiloxane | |
WO2021035250A1 (en) | Antimicrobial composition comprising alkylated polyvinylpyrrolidone polymer | |
JP4781664B2 (ja) | 抗菌剤 | |
JP4781663B2 (ja) | 抗菌剤 | |
BRPI0814611B1 (pt) | Composition, process for preparing a composition, and use of a composition |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20110715 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20110715 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20130117 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130129 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130401 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130604 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20130801 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20130808 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20131204 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20140203 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140501 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20140908 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20141008 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5631735 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |