JP5208121B2 - 連続した高圧力送出システム - Google Patents
連続した高圧力送出システム Download PDFInfo
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- JP5208121B2 JP5208121B2 JP2009531563A JP2009531563A JP5208121B2 JP 5208121 B2 JP5208121 B2 JP 5208121B2 JP 2009531563 A JP2009531563 A JP 2009531563A JP 2009531563 A JP2009531563 A JP 2009531563A JP 5208121 B2 JP5208121 B2 JP 5208121B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
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- A—HUMAN NECESSITIES
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- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
- A61M11/007—Syringe-type or piston-type sprayers or atomisers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
- A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
- A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
- A61M11/042—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters electrical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
- A61M15/025—Bubble jet droplet ejection devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
- A61M16/022—Control means therefor
- A61M16/024—Control means therefor including calculation means, e.g. using a processor
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- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
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- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
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- A—HUMAN NECESSITIES
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- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/105—Filters
- A61M16/106—Filters in a path
- A61M16/1065—Filters in a path in the expiratory path
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
- A61M2205/128—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated valves
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- A—HUMAN NECESSITIES
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3368—Temperature
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- A—HUMAN NECESSITIES
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/502—User interfaces, e.g. screens or keyboards
- A61M2205/505—Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mechanical Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicinal Preparation (AREA)
- Nozzles (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Description
本出願は2006年10月2日に出願され、本明細書に引用によりその全体が合体される米国特許仮出願第60/849,038号に対して優先権を主張する。
Claims (5)
- 薬物送出システムであって、
前記薬物送出システムは、エアロゾル発生器ユニットを有し、
前記エアロゾル発生器ユニットは、
(i)液体調合物を少なくとも部分的に気化するように構成された毛細管流路と、
(ii)前記毛細管流路中で前記液体調合物を少なくとも部分的に気化するのに有効な温度範囲まで前記毛細管流路を加熱するように作動可能な少なくとも1つのヒータ本体であって、前記毛細管流路がその中に適合する大きさに作られている前記ヒータ本体と、
(iii) 前記ヒータ本体に収容され、ガスが前記ヒータ本体によって加熱されて加熱されたガスを生成するように構成されている、少なくとも1つのガス流路と、を有し、
前記薬物送出システムは、
前記エアロゾル発生器ユニットに前記液体調合物を供給するように構成されているポンプユニットと、
前記エアロゾル発生器ユニットの出口部に流体連絡する入口端部と、患者の肺を換気する患者インターフェースに接続するように構成されている出口部と、を有する流路と、
前記エアロゾル発生器ユニットによって生成されるエアロゾルを前記加熱されたガスと混合するときに、エアロゾルの凝縮を低減しながら混合されたエアロゾルを生成し、かつ前記混合されたエアロゾルを前記流路の入口端部に向けて送出するように構成されているエアロゾルトランジションアダプターと、
前記エアロゾル発生器ユニットと前記ポンプユニットを作動させる制御システムと、を有し、
前記制御システムは、エアロゾルの凝縮を低減しながら混合されたエアロゾルを生成するように、前記液体調合物及び前記ガスの加熱温度を制御し、かつ前記ガス及び前記エアロゾルの流速を制御し、かつ前記エアロゾルと前記加熱されたガスとの混合を制御するように構成されていることを特徴とする薬物送出システム。 - 前記少なくとも1つのガス流路は、前記ガスがさや状ガスサブアセンブリによって加熱するように配置された前記さや状ガスサブアセンブリと適合するように構成された管状部材であることを特徴とする請求項1に記載の薬物送出システム。
- 約1〜6L/分の流量でガスを供給する、前記エアロゾルトランジションアダプターに接続された加圧ガス源を更に含むことを特徴とする請求項1に記載の薬物送出システム。
- 前記エアロゾル発生器ユニットは、使い捨てアセンブリであり、
前記使い捨てアセンブリは、
前記毛細管中の液体調合物が加熱されて前記液体調合物の少なくともいくらかが気化するときにエアロゾルを生成するように構成された、前記毛細管と、
1つのシリンジと、前記毛細管の入口部に前記液体調合物を供給するように作動可能な1組の弁とを含むシリンジアセンブリと、
換気されたまたは病院のガス供給を受け入れるように作動可能なさや状ガスチューブを含むさや状ガスチューブサブアセンブリと、
前記エアロゾルトランジションアダプターと、
を有することを特徴とする請求項1に記載の薬物送出システム。 - 前記使い捨てアセンブリを収容するために適合した使い捨てアセンブリハウジングを更に含み、
前記使い捨てアセンブリハウジングは、ヒータ本体を含み、
前記ヒータ本体は、
前記毛細管を収容するために適合した流路と、底部ヒータサブアセンブリ内の長手方向に配置された少なくとも1つの加熱ユニットとを有する、前記底部ヒータサブアセンブリと、
頂部ヒータサブアセンブリと、
前記さや状ガスチューブと、下部さや状ガスサブアセンブリ内に配置された少なくとも1つの加熱ユニットとを受け入れるように操作可能な流路を有する、前記下部さや状ガスサブアセンブリと、
上部さや状ガスサブアセンブリと、
を有することを特徴とする請求項4に記載の薬物送出システム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84903806P | 2006-10-02 | 2006-10-02 | |
US60/849,038 | 2006-10-02 | ||
PCT/US2007/080219 WO2008042912A2 (en) | 2006-10-02 | 2007-10-02 | Continuous high pressure delivery system |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010505540A JP2010505540A (ja) | 2010-02-25 |
JP5208121B2 true JP5208121B2 (ja) | 2013-06-12 |
Family
ID=39166806
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009531563A Active JP5208121B2 (ja) | 2006-10-02 | 2007-10-02 | 連続した高圧力送出システム |
Country Status (10)
Country | Link |
---|---|
US (3) | US8251055B2 (ja) |
EP (2) | EP2083894B1 (ja) |
JP (1) | JP5208121B2 (ja) |
KR (1) | KR101413124B1 (ja) |
CN (1) | CN101583394B (ja) |
ES (1) | ES2675369T3 (ja) |
PL (1) | PL2083894T3 (ja) |
PT (1) | PT2083894T (ja) |
TR (1) | TR201808388T4 (ja) |
WO (1) | WO2008042912A2 (ja) |
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CA2683353C (en) | 2008-10-22 | 2015-12-15 | Trudell Medical International | Modular aerosol delivery system |
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US8171094B2 (en) * | 2010-01-19 | 2012-05-01 | Event Medical, Inc. | System and method for communicating over a network with a medical device |
US8517729B2 (en) * | 2010-03-04 | 2013-08-27 | The University of Western Ontario and Trudell Medical International | Oral mouthpiece and method for the use thereof |
US8974771B2 (en) * | 2010-03-09 | 2015-03-10 | Penn-Century, Inc. | Apparatus and method for aerosol delivery to the lungs or other locations of the body |
AT508244B1 (de) | 2010-03-10 | 2010-12-15 | Helmut Dr Buchberger | Inhalatorkomponente |
US10307549B2 (en) | 2011-02-25 | 2019-06-04 | Koninklijke Philips N.V. | Aerosol generating device for nebulizing a liquid and a method of temperature control of a liquid to be nebulized |
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- 2007-10-02 ES ES07843691.2T patent/ES2675369T3/es active Active
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CN101583394A (zh) | 2009-11-18 |
PL2083894T3 (pl) | 2019-02-28 |
WO2008042912A3 (en) | 2008-10-09 |
ES2675369T3 (es) | 2018-07-10 |
TR201808388T4 (tr) | 2018-07-23 |
US20130068224A1 (en) | 2013-03-21 |
US20080110458A1 (en) | 2008-05-15 |
JP2010505540A (ja) | 2010-02-25 |
EP3372266A1 (en) | 2018-09-12 |
WO2008042912A2 (en) | 2008-04-10 |
EP2083894B1 (en) | 2018-05-30 |
PT2083894T (pt) | 2018-10-24 |
KR20090087440A (ko) | 2009-08-17 |
EP3372266B1 (en) | 2020-01-01 |
CN101583394B (zh) | 2014-06-25 |
KR101413124B1 (ko) | 2014-07-01 |
EP2083894A2 (en) | 2009-08-05 |
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