JP4899019B2 - Wound dressing and its manufacturing method - Google Patents
Wound dressing and its manufacturing method Download PDFInfo
- Publication number
- JP4899019B2 JP4899019B2 JP2007269892A JP2007269892A JP4899019B2 JP 4899019 B2 JP4899019 B2 JP 4899019B2 JP 2007269892 A JP2007269892 A JP 2007269892A JP 2007269892 A JP2007269892 A JP 2007269892A JP 4899019 B2 JP4899019 B2 JP 4899019B2
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- JP
- Japan
- Prior art keywords
- perforated material
- silicone resin
- absorbent body
- hole
- wound dressing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Description
本発明は、傷の保護、治療に使用する傷手当用品とその製造方法に関する。 The present invention relates to a wound care product used for wound protection and treatment, and a method for producing the same.
熱傷、褥瘡、及びその他の損傷の治療において、傷を保護し、傷からの体液を吸収するために、従来、ガーゼ、脱脂綿、吸収性繊維からなる層を含む多層構造のパッド等の傷手当用品が用いられている。
しかし、これらの傷手当用品は、手当用品を適用後交換する際に創傷面を傷つけ、痛みや、出血、創傷の治癒遅延を招くことがあった。
一方で、傷手当用品は、固定等の取り扱い性、体液の漏れによる傷周辺皮膚への浸軟を防止する目的で、創傷部また周辺皮膚部に対し粘着性であることが望ましい。
しかしながら、従来の粘着層（例えばアクリル系接着剤、ゴム系接着剤）を備えた傷手当用品は、粘着力が強すぎる傾向があり、交換時に創傷部に固着することで脆弱な新生表皮組織に損傷を与え、組織の治療を遅延する原因となっていた。
In the treatment of burns, pressure ulcers, and other injuries, wound care products such as multi-layered pads that conventionally include layers of gauze, absorbent cotton, absorbent fibers to protect the wound and absorb fluid from the wound Is used.
However, these wound dressings may damage the wound surface when the dressing is replaced after application, leading to pain, bleeding, and delayed healing of the wound.
On the other hand, it is desirable that the wound care product is sticky to the wound part or the peripheral skin part for the purpose of preventing handling of fixing and the like and the maceration of the skin around the wound due to leakage of body fluid.
However, wound care products provided with conventional adhesive layers (for example, acrylic adhesives, rubber adhesives) tend to have too strong an adhesive force, and can be attached to the wound area at the time of replacement. Caused damage and delayed tissue treatment.
このような背景から、傷手当用品において、創傷部に接触する材料としては、生体組織に対し微弱な粘着力を有するものを用いることが好ましい。特には、生体に対する親和性の低いシリコーン樹脂からなる材料が好ましい。 From such a background, in the wound care product, it is preferable to use a material having a weak adhesive force with respect to a living tissue as a material that contacts the wound part. In particular, a material made of a silicone resin having a low affinity for a living body is preferable.
この粘着性のシリコーン樹脂を用いた傷手当用品の例をあげると、例えば、特許文献１ではシリコーンゲルが弾性網状補強物の貫通孔を残して、網の全構成要素をシールした傷手当用品を開示している。特許文献１の技術によれば、このシリコーン樹脂を創傷接触材料に用いることで傷への固着性は改善する。
しかしながら、特許文献１記載の傷手当用品は吸収性を有さないことから、何らかの吸収材料と併用する手間があった。また、この傷手当用品に、仮に吸収体を併用した場合には、傷手当用品の貫通孔の部分から吸収体が露出されてしまう。このため貫通孔の部分においては、創傷部の新生組織と容易に固着する危険性があった。
As an example of a wound dressing product using this adhesive silicone resin, for example, Patent Document 1 discloses a wound dressing product in which a silicone gel leaves a through hole of an elastic mesh reinforcement and seals all components of the mesh. Disclosure. According to the technique of patent document 1, the adhesiveness to a wound improves by using this silicone resin for a wound contact material.
However, since the wound dressing described in Patent Document 1 does not have absorbability, it has been troublesome to use it in combination with some absorbent material. In addition, if an absorbent body is used in combination with the wound dressing product, the absorbent body is exposed from the through hole portion of the wound dressing product. For this reason, in the part of the through-hole, there existed a risk of adhering easily with the new tissue of a wound part.
また、特許文献２では、空気不浸透性且つ体液不浸透性の孔開き層材料（キャリヤー材料）の片面をシリコーンゲルで被膜した傷手当用品が教示されている。この傷手当用品は吸収体を具備しているため、特許文献１の課題であった吸収体と併用する手間がない。しかしながら、特許文献２記載の傷手当用品は、特許文献1記載の傷手当用品と同じく、貫通孔の部分においては適用した吸収体が露出された状態になるため、新生組織と容易に固着する危険性に関しては解決できていない。 Patent Document 2 teaches a wound dressing product in which one side of an air-impermeable and body fluid-impermeable perforated layer material (carrier material) is coated with a silicone gel. Since this wound dressing has an absorbent body, there is no need to use it together with the absorbent body, which was the problem of Patent Document 1. However, the wound dressing product described in Patent Document 2 is the same as the wound dressing product described in Patent Document 1, because the applied absorbent body is exposed in the through-hole portion, so that there is a risk of easily sticking to the new tissue. It has not been solved with regard to sex.
この発明は、上記のような点に鑑みてなされたもので、本発明の課題は、吸収性を備え、且つ傷に対する固着性を改善した傷手当用品を提供することにある。 This invention is made | formed in view of the above points, and the subject of this invention is providing the wound care article which was provided with the absorptivity and improved the adhesiveness with respect to a damage | wound.
上述の課題を解決するため本発明によれば、上面及び底面を有し複数の貫通孔を有する孔開き材料と、孔開き材料の上面に配置される吸収体とを備えた傷手当用品において、孔開き材料の少なくとも底面が、貫通孔の全部が塞がれることがないように貫通孔の少なくとも一部を残してシリコーン樹脂で被覆され、吸収体の孔開き材料の貫通孔と対向する部分の一部が、シリコーン樹脂で被覆され、孔開き材料の底面側から吸収体内部へ液体が通過し得るようにしたことを特徴とする。前記発明において、孔開き材料の上面が、貫通孔の全部が塞がれることがないように貫通孔の少なくとも一部を残してシリコーン樹脂で被覆されることが好ましい。 In order to solve the above-described problem, according to the present invention, in a wound dressing product comprising a perforated material having a top surface and a bottom surface and having a plurality of through holes, and an absorber disposed on the top surface of the perforated material, At least the bottom surface of the perforated material is covered with silicone resin leaving at least a part of the through hole so that the entire through hole is not blocked, and the portion of the absorbent body facing the through hole of the perforated material A part thereof is covered with a silicone resin so that liquid can pass from the bottom surface side of the perforated material into the absorber. In the above invention, it is preferable that the top surface of the perforated material is covered with a silicone resin so that at least a part of the through hole is left so that the entire through hole is not blocked.
また、本発明は、上面及び底面を有し複数の貫通孔を有する孔開き材料と、孔開き材料の上面に配置される吸収体とを備えた傷手当用品において、孔開き材料の上面及び底面が、貫通孔の全部が塞がれることがないように貫通孔の少なくとも一部を残してシリコーン樹脂で被覆され、吸収体の孔開き材料の貫通孔と対向する部分の一部が、シリコーン樹脂で被覆され、孔開き材料と吸収体とが、孔開き材料の上面に位置するシリコーン樹脂により接着され、孔開き材料の底面側から吸収体内部へ液体が通過し得るようにしたことを特徴とする。 The present invention also relates to a wound dressing article comprising a perforated material having a top surface and a bottom surface and having a plurality of through holes, and an absorbent body disposed on the top surface of the perforated material. However, at least a part of the through hole is covered with a silicone resin so that the entire through hole is not blocked, and a part of the portion of the absorbent body facing the through hole of the opening material is a silicone resin. And the perforated material and the absorbent body are bonded by a silicone resin located on the upper surface of the perforated material so that liquid can pass from the bottom surface side of the perforated material into the absorbent body. To do.
さらに、前記発明の実施態様としては下記の発明が好ましい。即ち、シリコーン樹脂は、粘着性ゲルとすることが好ましい。また、孔開き材料の貫通孔の内周面が、貫通孔の全部が塞がれることなくシリコーン樹脂で被覆されていることが好ましい。さらに、シリコーン樹脂が、孔開き材料の底面から内部に浸透し孔開き材料の上面に至っていることが好ましい。また、吸収体の孔開き材料の貫通孔と対向する部分が、孔開き材料の底面側から吸収体内部へ液体が通過することを阻害しない程度にシリコーン樹脂で被覆されていることが好ましい。さらに、孔開き材料及び吸収体を被覆するシリコーン樹脂量が、１５０〜３５０ｇ／ｍ2であることが好ましい。また、孔開き材料が、厚さ０．０５〜０．７ｍｍの編布であることが好ましい。さらに、孔開き材料が、０．０1〜１０ｍｍ2の貫通孔平均断面積と、５〜７０％の開孔率とを備えることが好ましい。 Furthermore, the following invention is preferable as an embodiment of the said invention. That is, the silicone resin is preferably an adhesive gel. Moreover, it is preferable that the inner peripheral surface of the through hole of the perforated material is covered with a silicone resin without blocking the entire through hole. Furthermore, it is preferable that the silicone resin penetrates into the inside from the bottom surface of the perforated material and reaches the top surface of the perforated material. Moreover, it is preferable that the part which opposes the through-hole of the apertured material of an absorber is coat | covered with the silicone resin to such an extent that it does not inhibit that a liquid passes into the absorber inside from the bottom face side of an apertured material. Furthermore, it is preferable that the amount of the silicone resin covering the perforated material and the absorber is 150 to 350 g / m 2 . In addition, the aperture material, and the knitted fabric der Turkey of thickness 0.05~0.7mm is preferable. Furthermore, it is preferable that the perforated material has a through-hole average cross-sectional area of 0.01 to 10 mm 2 and a porosity of 5 to 70%.
また、前記傷手当用品の製造方法の発明としては、下記の発明が好ましい。即ち、
上面及び底面を有し複数の貫通孔を有する孔開き材料と、孔開き材料の上面に配置される吸収体とを備え、孔開き材料の少なくとも底面が、貫通孔の全部が塞がれることがないように貫通孔の少なくとも一部を残してシリコーン樹脂で被覆され、吸収体の孔開き材料の貫通孔と対向する部分の一部が、シリコーン樹脂で被覆され、孔開き材料の底面側から吸収体内部へ液体が通過し得るようにした傷手当用品の製造方法であって、下記の工程を含むことを特徴とする。
（Ｐ１）剥離シートにシリコーン樹脂を塗工する工程
（Ｐ２）硬化前のシリコーン樹脂塗工面に孔開き材料を載せ、孔開き材料の上面に吸収体を載せ、孔開き材料及び吸収体にシリコーン樹脂を被覆する工程
（Ｐ３）シリコーン樹脂を加熱硬化させる工程
In addition, as an invention of the method for manufacturing the wound dressing, the following invention is preferable. That is,
A perforated material having a top surface and a bottom surface and having a plurality of through-holes, and an absorber disposed on the top surface of the perforated material, wherein at least the bottom surface of the perforated material is closed over all of the through-holes So that at least part of the through-holes is covered with silicone resin, and the part of the absorber facing the through-hole of the perforated material is partly covered with silicone resin and absorbed from the bottom side of the perforated material A method of manufacturing a wound care product that allows a liquid to pass into the body, comprising the following steps.
(P1) Step of applying a silicone resin to the release sheet (P2) Putting a perforated material on the silicone resin coated surface before curing, placing an absorbent body on the upper surface of the perforated material, and then placing a silicone resin on the perforated material and the absorbent body (P3) The step of heat curing the silicone resin
さらに、本発明の製造方法としては、下記の発明が好ましい。即ち、
上面及び底面を有し複数の貫通孔を有する孔開き材料と、孔開き材料の上面に配置される吸収体とを備え、孔開き材料の上面及び底面が、貫通孔の全部が塞がれることがないように貫通孔の少なくとも一部を残してシリコーン樹脂で被覆され、吸収体の孔開き材料の貫通孔と対向する部分の一部が、シリコーン樹脂で被覆され、孔開き材料と吸収体とが、孔開き材料の上面に位置するシリコーン樹脂により接着され、孔開き材料の底面側から吸収体内部へ液体が通過し得るようにした傷手当用品の製造方法であって、下記の工程を含むことを特徴とする。
（Ｐ１）剥離シートにシリコーン樹脂を塗工する工程
（Ｐ２Ａ）硬化前のシリコーン樹脂塗工面に孔開き材料を載せ、孔開き材料の上面に吸収体を載せ、シリコーン樹脂を孔開き材料の底面から内部に浸透させ孔開き材料の上面に至らせることで孔開き材料と吸収体とをシリコーン樹脂により接着すると共に、孔開き材料及び吸収体にシリコーン樹脂を被覆する工程
（Ｐ３）シリコーン樹脂を加熱硬化させる工程
Furthermore, as a manufacturing method of this invention, the following invention is preferable. That is,
A perforated material having a top surface and a bottom surface and having a plurality of through-holes and an absorber disposed on the top surface of the perforated material, the top surface and the bottom surface of the perforated material are all blocked by the through-holes So that there is at least part of the through-holes and is covered with silicone resin, and part of the portion of the absorbent body facing the through-holes of the opening material is covered with silicone resin, Is a method of manufacturing a wound dressing article that is bonded by a silicone resin located on the top surface of the perforated material and allows liquid to pass from the bottom surface side of the perforated material into the absorbent body, including the following steps: It is characterized by that.
(P1) Step of applying silicone resin to release sheet (P2A) A perforated material is placed on the silicone resin coated surface before curing, an absorber is placed on the top surface of the perforated material, and the silicone resin is applied from the bottom surface of the perforated material. A process of adhering the perforated material and the absorber with the silicone resin by penetrating the inside and reaching the upper surface of the perforated material, and covering the perforated material and the absorber with the silicone resin (P3). Process
本発明の傷手当用品は、傷接触面となる孔開き材料及び吸収体の双方がシリコーン樹脂で被覆されているため、新生肉芽組織が孔開き材料の貫通孔から侵入してきても傷手当用品が傷面と強く付着することを防止でき、脆弱な新生表皮組織に損傷を与えることなく傷手当用品の除去、交換等を行うことができる。また、本発明の傷手当用品は、傷からの滲出液を傷表面から速やかに吸収体に吸い上げるため、過剰な滲出液による皮膚浸軟や創治癒遅延も防ぐことができる。さらに、本発明の製造方法によれば、上記の傷手当用品が容易に製造できる。 In the wound dressing of the present invention, since both the perforated material and the absorbent body that become the wound contact surface are coated with the silicone resin, the wound dressing is not damaged even if the new granulation tissue enters from the through hole of the perforated material. Strong adhesion to the wound surface can be prevented, and the wound dressing can be removed and replaced without damaging the fragile new epidermal tissue. In addition, since the wound care product of the present invention quickly absorbs exudate from the wound from the wound surface to the absorbent body, it can prevent skin maceration and wound healing delay due to excessive exudate. Furthermore, according to the manufacturing method of the present invention, the above wound care product can be easily manufactured.
図１〜５に基づき、本発明の実施形態について以下に述べる。各実施形態の共通部分には、同じ番号の符号を用いて説明する。 An embodiment of the present invention will be described below based on FIGS. The common parts of each embodiment will be described using the same reference numerals.
図１は、本発明の傷手当用品に係る実施形態で、ａ）は上面からみた斜視図、ｂ）は底面からみた斜視図、ｃ）はａ）図のＣ−Ｃ線に沿う拡大断面図を示す。 FIG. 1 is an embodiment according to the wound care product of the present invention, in which a) is a perspective view seen from the top surface, b) is a perspective view seen from the bottom surface, and c) is an enlarged sectional view taken along line CC in FIG. Indicates.
本発明の傷手当用品１０は、上面及び底面を有する孔開き材料２０と、孔開き材料２０の上面に配置される吸収体３０とを備える。孔開き材料２０は、編布から形成され、その編構造により複数の貫通孔２１が形成され、その底面側が傷に対向する面となる。
孔開き材料２０の上面、底面、及び貫通孔２１の内周面２２は、貫通孔２１の孔全部が塞がれることがないように孔の少なくとも一部（本実施形態では貫通孔の全部）を残してゲル状の粘着性シリコーン樹脂４０で被覆される。すなわち、本発明の傷手当用品１０は、孔開き材料の底面側から吸収体３０の内部へ血液、滲出液等の液体が通過し得るように、孔開き材料２０の上面から底面を貫通する孔の少なくとも一部（本実施形態では貫通孔の全部）を残したままシリコーン樹脂４０が孔開き材料２０を被覆する構成を有する。なお、後述するように、通常は、傷手当用品の使用前におけるシリコーン樹脂被覆層および孔開き材料の保護用材料として、図示しない剥離シートが、シリコーン樹脂４０の底面側に設けられる。
また、吸収体３０においては、孔開き材料２０の貫通孔２１と対向する部分３１の一部が、孔開き材料の底面側から吸収体内部へ血液、滲出液等の液体が通過することを阻害しない程度にゲル状の粘着性シリコーン樹脂で被覆されている。吸収体３０として、後述するように、例えば、不織布を用いた場合、不織布の一部にシリコーン樹脂がからんで付着し、残りの部分には、シリコーン樹脂が付着せずに液体が通過可能な状態となるように、シリコーン樹脂で不織布の一部が被覆される。
The wound dressing 10 of the present invention includes a perforated material 20 having a top surface and a bottom surface, and an absorbent body 30 disposed on the top surface of the perforated material 20. The perforated material 20 is formed from a knitted fabric, and a plurality of through-holes 21 are formed by the knitted structure, and the bottom surface thereof is a surface facing the scratch.
The top surface and bottom surface of the perforated material 20 and the inner peripheral surface 22 of the through hole 21 are at least part of the hole so that the whole hole of the through hole 21 is not blocked (all of the through holes in this embodiment). And is covered with a gel-like adhesive silicone resin 40. That is, the wound dressing 10 of the present invention has a hole that penetrates from the top surface to the bottom surface of the perforated material 20 so that liquid such as blood and exudate can pass from the bottom surface side of the perforated material into the absorber 30. In this embodiment, the silicone resin 40 covers the perforated material 20 while leaving at least a part (all of the through holes in this embodiment). As will be described later, usually, a release sheet (not shown) is provided on the bottom side of the silicone resin 40 as a protective material for the silicone resin coating layer and the perforated material before use of the wound dressing.
Further, in the absorbent body 30, a part of the portion 31 of the perforated material 20 facing the through hole 21 inhibits the passage of liquid such as blood and exudate from the bottom surface side of the perforated material into the absorbent body. It is covered with a gel-like adhesive silicone resin to such an extent that it does not. As will be described later, for example, when a non-woven fabric is used as the absorbent body 30, the silicone resin is entangled and adhered to a part of the non-woven fabric, and the liquid can pass through the remaining part without adhering the silicone resin. Then, a part of the nonwoven fabric is coated with a silicone resin.
図１に係る実施形態のように、孔開き材料２０の表面全部をシリコーン樹脂４０で被覆し、さらに吸収体３０の孔開き材料２０の貫通孔２１と対向する部分３１の一部をシリコーン樹脂４０で被覆することにより、治癒により新生肉芽組織が孔開き材料の貫通孔に侵入した場合でも、傷に対する高い非固着性を維持することができ、かつ傷からの滲出液を傷表面から速やかに吸収体に吸い上げることができる。 As in the embodiment according to FIG. 1, the entire surface of the perforated material 20 is covered with the silicone resin 40, and a part of the portion 31 of the absorbent body 30 that faces the through-hole 21 of the perforated material 20 is covered with the silicone resin 40. By covering with, even if the new granulation tissue penetrates into the through-hole of the perforated material due to healing, it can maintain high non-adherence to the wound and absorb exudate from the wound quickly from the wound surface Can be sucked into the body.
また、図１の実施形態においては、ゲル状の粘着性シリコーン樹脂４０が孔開き材料２０の底面からその編布内部に浸透し、孔開き材料の上面に至っている。そして、孔開き材料の上面に存在するこのシリコーン樹脂４０により、孔開き材料２０と吸収体３０とが接着されている。このように、図１の実施形態に係る傷手当用品１０は、１種類の粘着性のシリコーン樹脂４０により、孔開き材料及び吸収体のシリコーン樹脂による被覆、並びに孔開き材料及び吸収体の一体化を行っているため、材料構成がシンプルで、製造工程が極めて簡単となる。 Further, in the embodiment of FIG. 1, the gel-like adhesive silicone resin 40 penetrates into the inside of the knitted fabric from the bottom surface of the perforated material 20 and reaches the top surface of the perforated material. And the perforated material 20 and the absorber 30 are adhere | attached by this silicone resin 40 which exists on the upper surface of a perforated material. As described above, the wound care product 10 according to the embodiment of FIG. 1 is formed by coating the perforated material and the absorbent body with the silicone resin, and integrating the perforated material and the absorbent body with one kind of adhesive silicone resin 40. Therefore, the material structure is simple and the manufacturing process becomes extremely simple.
５０は、吸収体３０の上面に被覆されるカバー材で、吸収体の汚染防止、傷手当用品の支持、吸収体からの汚染物質脱落防止などの機能がある。図１の実施形態では、カバー材５０として液体浸透性の不織布を用いているが、このようなカバー材は傷からの滲出液が多量に出る場合に特に有利な構成である。つまり、過剰な滲出液がカバー材から滲みでてくるので、カバー材の上に本発明の傷手当用品とは別の吸収パッドを載置すれば、本発明の傷手当用品を除去することなく必要に応じてこの吸収パッドのみを交換することができ、滲出液管理を簡便に行うことができる。 Reference numeral 50 denotes a cover material that covers the upper surface of the absorbent body 30 and has functions such as preventing contamination of the absorbent body, supporting wound care products, and preventing contaminants from falling off the absorbent body. In the embodiment of FIG. 1, a liquid-permeable nonwoven fabric is used as the cover material 50, but such a cover material is a particularly advantageous configuration when a large amount of exudate from the scratches comes out. In other words, since excessive exudate oozes from the cover material, if an absorbent pad different from the wound care product of the present invention is placed on the cover material, the wound care product of the present invention is not removed. If necessary, only this absorption pad can be replaced, and the exudate can be managed easily.
なお、図１の実施形態では、孔開き材料２０の表面全部（上面、底面、及び貫通孔の内周面）に粘着性のシリコーン樹脂を被覆した例を示したが、孔開き材料の底面のみを被覆する態様、孔開き材料の底面及び上面のみを被覆する態様にしてもよい。
また、孔開き材料２０は、貫通孔２１の全部がシリコーン樹脂で塞がれないようにシリコーン樹脂で被覆されることが好ましいが、吸収体内部への通液を阻害しなければ貫通孔２１の一部がシリコーン樹脂で塞がれていても良い。
また、孔開き材料２０と吸収体３０との接着は、アクリル系粘着剤、ゴム系粘着剤、ポリウレタン系粘着剤等のシリコーン樹脂以外の粘着剤で接着してもよいし、熱溶着により接着してもよい。
In the embodiment of FIG. 1, an example in which the entire surface (the upper surface, the bottom surface, and the inner peripheral surface of the through hole) of the perforated material 20 is coated with an adhesive silicone resin is shown, but only the bottom surface of the perforated material is shown. It is also possible to adopt a mode in which only the bottom and top surfaces of the perforated material are coated.
Further, the perforated material 20 is preferably coated with a silicone resin so that the entire through-hole 21 is not blocked with the silicone resin. A part may be blocked with silicone resin.
Further, the perforated material 20 and the absorbent body 30 may be bonded with a pressure-sensitive adhesive other than a silicone resin such as an acrylic pressure-sensitive adhesive, a rubber pressure-sensitive adhesive, or a polyurethane pressure-sensitive adhesive, or by heat welding. May be.
図２は、本発明の傷手当用品に係る図１とは異なる実施形態で、ａ）は上面からみた斜視図、ｂ）は底面からみた斜視図、ｃ）はａ）図のＣ−Ｃ線に沿う拡大断面図である。
図２の実施形態は、図１で示した実施形態と、カバー材５１が異なる。即ち、カバー材５１は、液体不浸透性且つ水蒸気透過性のプラスチックフィルムからなり、その底面に粘着性のシリコーン樹脂５２が被覆され、更にその外周縁が吸収体３０の外周縁より外側に伸びている。この傷手当用品を患部に固定した際には、前記の外側に伸びた部分が吸収体以下の部材を覆う状態となる。
従って、図２の実施形態によれば、カバー材５１により、簡便に患部に傷手当用品を固定でき、滲出液が過剰な場合でも吸収体の外周縁から滲出液が漏れ出ることを防止でき、さらに傷を適度な湿潤環境に保つことができるので創治癒促進をはかることができる。
FIG. 2 is an embodiment different from FIG. 1 according to the wound dressing of the present invention, in which a) is a perspective view seen from the top, b) a perspective view seen from the bottom, and c) a CC line in FIG. FIG.
The embodiment shown in FIG. 2 is different from the embodiment shown in FIG. That is, the cover material 51 is made of a liquid-impermeable and water-vapor-permeable plastic film, the bottom surface of which is coated with an adhesive silicone resin 52, and the outer peripheral edge extends outward from the outer peripheral edge of the absorber 30. Yes. When this wound dressing is fixed to the affected area, the portion extending outwardly covers the member below the absorber.
Therefore, according to the embodiment of FIG. 2, the cover material 51 can easily fix the wound dressing to the affected part, and can prevent the exudate from leaking from the outer peripheral edge of the absorbent body even when the exudate is excessive, Furthermore, since wounds can be maintained in a moderately moist environment, wound healing can be promoted.
図３は、本発明の図１に係る傷手当用品の形状を変えた実施形態である。この実施形態によれば、踵、肘、膝、仙骨、前腕などの突出部、湾曲部に貼付した場合でも、患部によくフィットし、シワなく傷手当用品を適用することができる。 FIG. 3 is an embodiment in which the shape of the wound dressing according to FIG. 1 of the present invention is changed. According to this embodiment, even when affixed to protrusions and curved parts such as the heel, elbow, knee, sacrum, and forearm, it fits well to the affected part and can apply wound care products without wrinkles.
次に図４および図５により、本発明の傷手当用品の製造方法を説明する。
本発明の傷手当用品は、Ｐ１、Ｐ２（Ｐ２Ａ）、Ｐ３の工程を順次経て製造される。なお、図５は、前記各工程を連続的に行なう状態を模式的に示す図であり、各工程は、実質的に図４と同様である。
Ｐ１の工程は、剥離シート６０にシリコーン樹脂４０を塗工する工程である。剥離シートとしては、シリコーン系やフッ素系の剥離剤により処理された剥離紙、剥離フィルム、又はポリカーボネート、ポリビニルアルコール、セロハン、ウレタン等のフィルムを使用することができる。
Ｐ２の工程では、Ｐ１の工程により塗工した硬化前のシリコーン樹脂塗工面４０に孔開き材料２０を載せ、さらに孔開き材料２０の上面に吸収体３０（この吸収体はカバー材５０を予め吸収体の上面に積層しておくことも可能である）を載せる。この際、シリコーン樹脂、孔開き材料、及び吸収体の積層は、図４および図５に示すようにほぼ同時に行っても良いし、孔開き材料を先にシリコーン樹脂上に供給し、次いで吸収体を供給するようにしてもよい。このように、シリコーン樹脂上に孔開き材料を載置し、さらにその上に吸収体を載置することで、孔開き材料の貫通孔以外の部分と、吸収体の孔開き材料の貫通孔に対向する部分にシリコーン樹脂が被覆される。
なお、このＰ２の工程としては、次に示すＰ２Ａの工程が特に好ましい。Ｐ２Ａの工程では、先ずＰ２の工程と同様に硬化前のシリコーン樹脂塗工面４０に孔開き材料２０を載せ、孔開き材料２０の上面に吸収体３０を載せる。次いで、これらの積層物に適当な荷重７０を加えるなどして、シリコーン樹脂４０を孔開き材料２０の底面から内部に浸透させ孔開き材料の上面に至らせることで孔開き材料２０と吸収体３０とをシリコーン樹脂４０により接着する。また、この孔開き材料２０と吸収体３０の接着と同時に、孔開き材料の貫通孔部分に存在するシリコーン樹脂を吸収体表面に吸収させ、吸収体の孔開き材料の貫通孔と対向する部分にシリコーン樹脂を被覆する。即ち、Ｐ２Ａの工程は、孔開き材料の貫通孔を塞がずに孔開き材料をシリコーン樹脂で被覆するとともに、吸収体にもシリコーン樹脂を被膜し、さらに、孔開き材料と吸収体との接着も同時に達成することができる工程である。
Ｐ３の工程は、Ｐ２（Ｐ２Ａ）の工程により孔開き材料と吸収体に塗工したシリコーン樹脂を加熱硬化させる工程であり、未硬化で液状のシリコーン樹脂がこの工程を経て硬化し、本発明の傷手当用品１０が完成する。
なお、シリコーン樹脂の種類や塗工量、孔開き材料と吸収体の種類、荷重の程度等をコントロールすることにより、本発明の種々の実施形態を製造することができる。
また、本発明の傷手当用品は、上記以外の方法でも製造することができ、例えば、孔開き材料を未硬化のシリコーン樹脂に浸漬し、余分なシリコーン樹脂を搾った後その上に吸収体を載せ、シリコーン樹脂を加熱硬化させ、その後スプレー等によりシリコーン樹脂を吹き付け、吸収体の孔開き材料の貫通孔と対向する部分をシリコーン樹脂で被覆する方法がある。
Next, with reference to FIG. 4 and FIG.
The wound dressing of the present invention is manufactured through the steps P1, P2 (P2A) and P3 in order. FIG. 5 is a diagram schematically showing a state in which the respective steps are continuously performed, and each step is substantially the same as FIG.
The process of P1 is a process of applying the silicone resin 40 to the release sheet 60. As the release sheet, a release paper, a release film, or a film of polycarbonate, polyvinyl alcohol, cellophane, urethane, or the like treated with a silicone-based or fluorine-based release agent can be used.
In the process of P2, the perforated material 20 is placed on the uncured silicone resin coated surface 40 applied in the process of P1, and the absorbent body 30 (this absorbent body absorbs the cover material 50 in advance) on the upper surface of the perforated material 20. It can also be stacked on top of the body). At this time, the lamination of the silicone resin, the perforated material, and the absorbent body may be performed almost simultaneously as shown in FIGS. 4 and 5, or the perforated material is first supplied onto the silicone resin, and then the absorbent body. May be supplied. In this way, by placing the perforated material on the silicone resin and further placing the absorbent body thereon, the portion other than the through hole of the perforated material and the through hole of the perforated material of the absorbent body The silicone resin is coated on the facing part.
In addition, as this process of P2, the process of P2A shown next is especially preferable. In the process of P2A, the perforated material 20 is first placed on the silicone resin coated surface 40 before curing, and the absorbent body 30 is placed on the upper surface of the perforated material 20, as in the process of P2. Next, by applying an appropriate load 70 to these laminates, the silicone resin 40 penetrates from the bottom surface of the perforated material 20 to the inside, and reaches the top surface of the perforated material 20 to thereby form the perforated material 20 and the absorber 30. Are bonded with a silicone resin 40. Further, simultaneously with the bonding of the perforated material 20 and the absorber 30, the silicone resin present in the through hole portion of the perforated material is absorbed by the surface of the absorber, and the portion of the absorbent body facing the through hole of the perforated material is absorbed. Cover with silicone resin. That is, in the process of P2A, the perforated material is covered with a silicone resin without closing the through hole of the perforated material, and the absorbent body is also coated with the silicone resin, and further the adhesion between the perforated material and the absorbent body Is a process that can be achieved simultaneously.
The process of P3 is a process of heat curing the silicone resin applied to the perforated material and the absorber in the process of P2 (P2A), and the uncured and liquid silicone resin is cured through this process. The wound dressing 10 is completed.
Various embodiments of the present invention can be produced by controlling the type of silicone resin, the coating amount, the type of perforated material and absorber, the degree of load, and the like.
The wound dressing of the present invention can also be produced by methods other than those described above. For example, a perforated material is immersed in an uncured silicone resin, and after excess silicone resin is squeezed, an absorbent body is placed thereon. There is a method in which the silicone resin is heated and cured, and then sprayed with a silicone resin by spraying or the like, and the portion of the absorbent body facing the through hole of the perforated material is coated with the silicone resin.
次に、本発明の傷手当用品を構成している各材料等について述べる。 Next, each material etc. which comprise the wound care article of this invention are described.
（孔開き材料）
本発明の傷手当用品に使用する孔開き材料は、上面及び底面を有し、底面側が傷に対向する面となる。孔開き材料は、上面から底面に連通する複数の貫通孔を有することが必要である。傷からの血液、滲出液などを、孔開き材料の貫通孔を通して吸収体に吸収させるためである。
孔開き材料に設ける貫通孔の平均断面積は、孔開き材料の表面において空孔１つ当たり０．０1〜１０ｍｍ2であることが好ましく、０．１〜５ｍｍ2であることが更に好ましい。貫通孔の平均断面積が０．０１ｍｍ2より小さいと、シリコーン樹脂で孔開き材料を被覆する際、シリコーン樹脂が孔開き材料の貫通孔を塞ぎ、滲出液が孔開き材料から吸収体に移動しなくなる恐れがある。また、貫通孔の平均断面積が１０ｍｍ2より大きいと、孔開き材料と創面との十分な接触面積が得られず、傷手当用品の傷に対する密着性が低下し滲出液が漏れる場合がある。
本発明の孔開き材料において、貫通孔の開孔率は、５〜７０％であることが好ましく、１５〜５０％であることが更に好ましい。貫通孔の開孔率が５％より小さいと、滲出液が孔開き材料から吸収体に移動しなくなる恐れがあり、７０％より大きいと孔開き材料と創面との十分な接触面積が得られず、傷手当用品の傷に対する密着性が低下し滲出液が漏れる場合がある。
特に好適な孔開き材料は、貫通孔の平均断面積が０．1〜１ｍｍ2であり、且つ、貫通孔の開孔率が１５〜４０％の範囲にあるものである。
また、孔開き材料の厚さは、滲出液の吸収体への移動性と創面への非固着性の観点から、０．０５〜０．７ｍｍの範囲であることが好ましい。
(Perforated material)
The perforated material used for the wound care product of the present invention has an upper surface and a bottom surface, and the bottom surface is a surface facing the wound. The perforated material needs to have a plurality of through holes communicating from the top surface to the bottom surface. This is because blood, exudate, and the like from the wound are absorbed by the absorbent body through the through hole of the perforated material.
The average cross-sectional area of the through holes provided in the perforated material is preferably 0.01 to 10 mm 2 per pore on the surface of the perforated material, and more preferably 0.1 to 5 mm 2 . If the average cross-sectional area of the through holes is less than 0.01 mm 2 , when the perforated material is coated with silicone resin, the silicone resin will block the through holes of the perforated material, and the exudate will move from the perforated material to the absorber. There is a risk of disappearing. In addition, if the average cross-sectional area of the through-hole is larger than 10 mm 2 , a sufficient contact area between the perforated material and the wound surface cannot be obtained, and the adhesion of the wound dressing to the wound may be reduced and the exudate may leak.
In the perforated material of the present invention, the aperture ratio of the through holes is preferably 5 to 70%, and more preferably 15 to 50%. If the opening ratio of the through holes is less than 5%, the exudate may not move from the opening material to the absorber, and if it is more than 70%, a sufficient contact area between the opening material and the wound surface cannot be obtained. In addition, the adhesiveness of the wound dressing to the wound may be reduced and the exudate may leak.
Particularly suitable perforated materials are those having an average cross-sectional area of the through holes of 0.1 to 1 mm 2 and a through hole ratio of 15 to 40%.
In addition, the thickness of the perforated material is preferably in the range of 0.05 to 0.7 mm from the viewpoint of the mobility of the exudate to the absorber and the non-adhesiveness to the wound surface.
本発明で使用可能な孔開き材料としては、貫通孔を有するシート状材料であれば特に限定されず、編布、織布、不織布、ネット等の繊維状材料、孔開きプラスチックフィルム等が挙げられる。好ましい孔開き材料は、液体浸透性の繊維状材料であるが、特に好ましくは、貫通孔形成が容易で、本発明の傷手当用品の製造方法にも最適な編布である。
孔開き材料は、これら材料の一種類を単独で使用してもよいし、同一又は異なる種類の材料をラミネートした積層構造のものであってもよい。
孔開き材料に用いる編布としては、経編及び緯編の各種編組織が利用できる。特に好適な編布は、平編生地、ゴム編生地、トリコット生地、ラッシェル生地である。織布は、平織、綾織及び朱子織のいずれであってもよい。不織布は、フリース形成法として、乾式法、湿式法及びスパンボンド法のいずれを使用したものであってもよく、繊維結合が、スパンレース法、ニードルパンチ法、ケミカルボンド法、ポイントシール法、サーマルボンド法等のいずれの方法で形成されたものであってもよい。
ネットは、複数の長繊維を網目が形成されるように適当な間隔をあけて配置し、これを熱融着や接着剤等の結合手段により繊維同士を結合して形成したものを使用できる。
編布、織布、不織布、ネット等の繊維状材料を構成する糸としては、モノフィラメント、マルチフィラメント、撚糸、カバードヤーン、コアヤーン等が利用でき、伸縮加工や嵩高加工等を施したものを利用してもよい。
繊維の種類も特に限定されず、ポリエステル系繊維、アクリル系繊維、ポリアミド系繊維、ポリウレタン系繊維、セルロース系繊維（綿、レーヨン、ポリノジック、リヨセル）、ポリオレフィン系繊維、ポリ塩化ビニル系繊維、ポリ塩化ビニリデン系繊維、ガラス繊維、カーボンファイバー繊維等が利用できる。
特に好ましい繊維材料は、熱可塑性のポリエステル系繊維、アクリル系繊維及びポリアミド系繊維である。
The perforated material that can be used in the present invention is not particularly limited as long as it is a sheet-like material having a through hole, and examples thereof include knitted fabrics, woven fabrics, nonwoven fabrics, nets and other fibrous materials, perforated plastic films, and the like. . The perforated material is preferably a liquid-permeable fibrous material, and particularly preferably a knitted fabric that is easy to form through-holes and is optimal for the method for producing a wound dressing according to the present invention.
As the perforated material, one type of these materials may be used alone, or a layered structure in which the same or different types of materials are laminated may be used.
As the knitted fabric used for the perforated material, various knitting structures of warp knitting and weft knitting can be used. Particularly suitable knitted fabrics are flat knitted fabric, rubber knitted fabric, tricot fabric, and raschel fabric. The woven fabric may be any of plain weave, twill weave and satin weave. The nonwoven fabric may be any one of a dry method, a wet method, and a spunbond method as a fleece forming method, and the fiber bonding is a spunlace method, a needle punch method, a chemical bond method, a point seal method, a thermal method It may be formed by any method such as a bond method.
The net can be formed by arranging a plurality of long fibers at appropriate intervals so that a mesh is formed, and bonding the fibers together by a bonding means such as heat fusion or adhesive.
Monofilaments, multifilaments, twisted yarns, covered yarns, core yarns, etc. can be used as yarns constituting fibrous materials such as knitted fabrics, woven fabrics, non-woven fabrics and nets. May be.
The type of fiber is not particularly limited, and polyester fiber, acrylic fiber, polyamide fiber, polyurethane fiber, cellulosic fiber (cotton, rayon, polynosic, lyocell), polyolefin fiber, polyvinyl chloride fiber, polychlorinated fiber. Vinylidene fibers, glass fibers, carbon fiber fibers and the like can be used.
Particularly preferred fiber materials are thermoplastic polyester fibers, acrylic fibers and polyamide fibers.
孔開き材料における貫通孔の配置は、特に限定されず、規則的に又はランダムに点在させてもよいし、格子状、波状、同心円状、渦巻き状等の所定パターンを形成して配置してもよいが、孔開き材料全体で均一な滲出液透過ができるように、均一間隔をあけて配置されていることが好ましい。
孔開き材料の貫通孔は、編布の編目による貫通孔、繊維の組織（糸の太さ、密度等を含む）のバランスにより布表面に生じる貫通孔、織布の経糸と緯糸の間に形成される空隙等の繊維材料が本来有するものであってもよいし、後加工で物理的に穿孔した貫通孔であってもよい。
これらの中でも、編布のループによる貫通孔又は編組織（糸の太さ、密度等を含む）のバランスにより布表面に生じる貫通孔は、繊維材料自体に人体へのフィット性があり、シリコーン樹脂層を塗布した際に貫通孔が閉塞され難いので、好適である。
The arrangement of the through holes in the perforated material is not particularly limited, and may be regularly or randomly interspersed, and may be arranged in a predetermined pattern such as a lattice shape, a wavy shape, a concentric shape, or a spiral shape. However, it is preferable that the perforated materials are arranged at a uniform interval so that the exudate can permeate uniformly.
The perforation hole of the perforated material is formed between the perforation hole due to the stitch of the knitted fabric, the through hole generated on the fabric surface due to the balance of the fiber structure (including yarn thickness, density, etc.), and between the warp and weft of the woven fabric It may be a fiber material such as a void originally formed, or may be a through hole physically perforated by post-processing.
Among these, the through-hole formed by the loop of the knitted fabric or the through-hole formed on the surface of the fabric due to the balance of the knitted structure (including yarn thickness, density, etc.) has a good fit to the human body in the fiber material itself, and is a silicone resin. This is preferable because the through-hole is not easily blocked when the layer is applied.
（吸収体）
本発明の傷手当用品に使用する吸収体は、傷からの血液、滲出液を吸収、保持するためのものであり、孔開き材料の上面に配置される。
吸収体は、不織布、編布、織布等の繊維状材料、フォーム材料、吸収性樹脂材料、吸水性粉末材料などからなるものを使用することができ、繊維状材料、フォーム材料が好ましい。吸収体は、これら材料の一種類を単独で使用してもよいし、同一又は異なる種類の材料をラミネートした積層構造のものであってもよい。
特に、繊維状材料からなるものが好ましく、セルロース系繊維（綿、レーヨン、ポリノジック、リヨセル）、ポリエステル系繊維、アクリル系繊維、ポリアミド系繊維、ポリウレタン系繊維、又はこれらの混合繊維が好適な繊維材料である。また、これらの繊維材料中に、吸収性樹脂材料、吸水性粉末材料などの吸水性の高い材料を混ぜ込むことができ、必要とされる吸収量を適宜調整することができる。
また、吸収体を構成する材料として、吸水時にゲルを形成する物質を含ませることが好ましく、このような材料を使用することで、創傷を湿潤状態に保ち、傷の治癒を促進することができる。ゲル形成材料としては、ナトリウムカルボキシメチルセルロース、ナトリウムカルボキシメチルセルロースの架橋物、デンプン−アクリル酸（塩）グラフト共重合体、アクリル酸(塩)重合体、デンプン−アクリロニトリル共重合体、多価アルコール等が好ましい。
(Absorber)
The absorbent body used in the wound care product of the present invention is for absorbing and holding blood and exudate from the wound, and is disposed on the top surface of the perforated material.
The absorbent body may be made of a fibrous material such as a nonwoven fabric, a knitted fabric, or a woven fabric, a foam material, an absorbent resin material, a water-absorbing powder material, and the like, and a fibrous material and a foam material are preferable. The absorber may use one kind of these materials alone, or may have a laminated structure in which the same or different kinds of materials are laminated.
In particular, those made of fibrous materials are preferable, and cellulosic fibers (cotton, rayon, polynosic, lyocell), polyester fibers, acrylic fibers, polyamide fibers, polyurethane fibers, or mixed fibers thereof are suitable fiber materials. It is. Moreover, highly absorbent materials such as absorbent resin materials and water absorbent powder materials can be mixed into these fiber materials, and the required amount of absorption can be adjusted as appropriate.
Moreover, it is preferable to include a substance that forms a gel upon water absorption as a material constituting the absorbent body. By using such a material, it is possible to keep the wound moist and promote healing of the wound. . As the gel forming material, sodium carboxymethyl cellulose, a crosslinked product of sodium carboxymethyl cellulose, starch-acrylic acid (salt) graft copolymer, acrylic acid (salt) polymer, starch-acrylonitrile copolymer, polyhydric alcohol, and the like are preferable. .
（シリコーン樹脂）
本発明の傷手当用品に使用するシリコーン樹脂は、傷に対する固着性を低減するために、孔開き材料の少なくとも底面と、吸収体の孔開き材料の貫通孔と対向する部分に被覆される。
本発明のシリコーン樹脂は、取り扱いの簡便性と、傷に対する固着性の観点から、粘着性を有するゲル状物質であることが好ましい。
シリコーン樹脂は、特に限定されず、付加反応型、過酸化反応型、又は縮合反応型のいずれを使用してもよいが、付加反応型のシリコーン樹脂が好ましい。
付加反応型シリコーン樹脂は、ケイ素原子に結合したアルケニル基を有するオルガノポリシロキサン（アルケニル基含有オルガノポリシロキサン）とヒドロシリル基（Ｓｉ−Ｈ）を有するオルガノポリシロキサン（ハイドロジェンオルガノポリシロキサン）とを、塩化白金酸等の白金化合物触媒を用いて、付加反応（ヒドロシリル化反応）させたものである。
付加反応型シリコーン樹脂は、その合成に用いるオルガノハイドロジェンポリシロキサンの量や、オルガノハイドロジェンポリシロキサン分子内のヒドロシリル基（Ｓｉ−Ｈ）の量を変化させることによって、架橋密度を調整することができる。これにより、シリコーン樹脂の硬さや粘着力を容易に調整することができる。本発明に使用する付加反応型シリコーン樹脂としては、ビニル基置換ポリジメチルシロキサンとオルガノハイドロジェンポリシロキサンとの付加反応物であることが好ましい。
シリコーン樹脂は、一種類を単独で使用しても、二種類以上を組み合わせて使用してもよい。シリコーン樹脂は、架橋等により硬化されていることが好ましい。シリコーン樹脂の硬化方法は、特に限定されず、加熱等により容易に架橋させることができる。
(Silicone resin)
The silicone resin used in the wound dressing product of the present invention is coated on at least the bottom surface of the perforated material and the portion of the absorbent body facing the through hole of the perforated material in order to reduce adhesion to the wound.
The silicone resin of the present invention is preferably a gel-like substance having adhesiveness from the viewpoint of easy handling and adhesion to scratches.
The silicone resin is not particularly limited, and any of an addition reaction type, a peroxide reaction type, or a condensation reaction type may be used, but an addition reaction type silicone resin is preferable.
The addition reaction type silicone resin comprises an organopolysiloxane having an alkenyl group bonded to a silicon atom (alkenyl group-containing organopolysiloxane) and an organopolysiloxane having a hydrosilyl group (Si-H) (hydrogen organopolysiloxane). This is an addition reaction (hydrosilylation reaction) using a platinum compound catalyst such as chloroplatinic acid.
The addition reaction type silicone resin can adjust the crosslinking density by changing the amount of organohydrogenpolysiloxane used for the synthesis and the amount of hydrosilyl group (Si-H) in the organohydrogenpolysiloxane molecule. it can. Thereby, the hardness and adhesive force of the silicone resin can be easily adjusted. The addition reaction type silicone resin used in the present invention is preferably an addition reaction product of vinyl group-substituted polydimethylsiloxane and organohydrogenpolysiloxane.
A silicone resin may be used individually by 1 type, or may be used in combination of 2 or more types. The silicone resin is preferably cured by crosslinking or the like. The curing method of the silicone resin is not particularly limited, and can be easily crosslinked by heating or the like.
また、シリコーン樹脂には、更に、薬剤、吸水性高分子化合物、ｐＨ調整剤等のその他の調整剤を、本発明の目的を損なわない程度において、適宜配合することができる。
薬剤の例としては、保湿、老化防止、美白等の目的で皮膚の生理機能を調整する物質や、傷の治癒を促進する物質、抗菌性を有する物質等を示すことができる。その具体例としては、スフィンゴ脂質、尿素、グリコール酸、アミノ酸及びその誘導体（アルギニン、システイン、グリシン、リシン、プロリン、セリン等）、タンパク質加水分解物（コラーゲン、エラスチン、ケラチン等）、ムコ多糖及びその誘導体（ヒアルロン酸、コンドロイチン硫酸、ヘパリン等）、ビタミンＢ群（チアミン、リボフラビン、ニコチン酸、ピリドキシン、ピリドキサール、ピリドキサミン、ビオチン、葉酸、シアノコバラミン等）、アスコルビン酸（ビタミンＣ及びその誘導体）、レチノイド（ビタミンＡ、レチナール、レチノイン酸等）、ビタミンＤ（Ｄ２、Ｄ３等）、ビタミンＥ及びその誘導体、カロチノイド（カロチン、リコピン、キサントフィル等）、酵素、補酵素、γ―オリザノール等が挙げられ、スフィンゴ脂質が特に好適である。スフィンゴ脂質としては、スフィンゴシンと脂肪酸が結合したセラミド、セラミドと糖が結合したスフィンゴ糖脂質が好ましい。セラミドは、天然、合成いずれのものを使用してもよく、タイプ１〜７のセラミドを挙げることができるが、タイプ２、５、７のセラミドが特に好ましい。スフィンゴ糖脂質としては、セレブロシド、ガラクトシルセラミド、グルコシルセラミド等が好ましい。
吸水性高分子化合物、ｐＨ調整剤としては公知のものを使用することができる。
Further, the silicone resin can be appropriately mixed with other adjusting agents such as a drug, a water-absorbing polymer compound, and a pH adjusting agent as long as the object of the present invention is not impaired.
Examples of the drug include substances that adjust the physiological functions of the skin for the purpose of moisturizing, preventing aging, and whitening, substances that promote wound healing, substances that have antibacterial properties, and the like. Specific examples include sphingolipids, urea, glycolic acid, amino acids and derivatives thereof (arginine, cysteine, glycine, lysine, proline, serine, etc.), protein hydrolysates (collagen, elastin, keratin, etc.), mucopolysaccharides and their Derivatives (hyaluronic acid, chondroitin sulfate, heparin, etc.), vitamin B group (thiamine, riboflavin, nicotinic acid, pyridoxine, pyridoxal, pyridoxamine, biotin, folic acid, cyanocobalamin, etc.), ascorbic acid (vitamin C and its derivatives), retinoid (vitamin A, retinal, retinoic acid, etc.), vitamin D (D2, D3, etc.), vitamin E and its derivatives, carotenoids (carotene, lycopene, xanthophyll, etc.), enzymes, coenzymes, γ-oryzanol, etc. Gore-lipid is particularly suitable. The sphingolipid is preferably a ceramide in which sphingosine and a fatty acid are bonded, or a glycosphingolipid in which ceramide and a sugar are bonded. As the ceramide, either natural or synthetic ceramide may be used, and examples include ceramides of types 1 to 7, and ceramides of types 2, 5, and 7 are particularly preferable. As the sphingoglycolipid, cerebroside, galactosylceramide, glucosylceramide and the like are preferable.
A well-known thing can be used as a water absorbing polymer compound and a pH adjuster.
（カバー材）
本発明の傷手当用品は、吸収体の汚染防止、傷手当用品の取り扱い性、吸収体からの汚染物質脱落防止の観点から、吸収体の上面にカバー材を被覆することが好ましい。
カバー材は、傷からの滲出液の量や使用する場面にあわせて選択することができ、滲出液の量が多い場合は液体浸透性の材料を用いるのが好ましく、滲出液の量がそれほど多くない場合は、液体不浸透性且つ水蒸気透過性の材料を用いるのが好ましい。
また、カバー材は、底面に粘着剤を被覆すると共に、その外形を孔開き材料及び吸収体よりも大きく形成することで、孔開き材料及び吸収体の外周縁より外側にでた部分により、患部に粘着固定することが可能となる。
カバー材の底面を被覆する粘着剤としては、孔開き材料及び吸収体を被覆するシリコーン樹脂と同様のものを使用できるが、例えば、アクリル系粘着剤、ゴム系粘着剤、吸水性高分子を含有する所謂ハイドロコロイド粘着剤等のシリコーン樹脂以外の粘着剤を用いることもできる。
カバー材の材料としては、不織布、編布、織布、ネット等の繊維状シート、合成樹脂フィルム、フォーム等をあげることができ、これら材料の適宜選択により液体浸透性の程度をコントロールすることができる。
(Cover material)
In the wound dressing product of the present invention, it is preferable to cover the upper surface of the absorbent body from the viewpoint of preventing contamination of the absorbent body, handling of the wound dressing product, and preventing contaminants from falling off the absorbent body.
The cover material can be selected according to the amount of exudate from the wound and the situation of use. When the amount of exudate is large, it is preferable to use a liquid-permeable material, and the amount of exudate is so large. If not, it is preferable to use a liquid impermeable and water vapor permeable material.
Further, the cover material covers the bottom surface with an adhesive and forms an outer shape larger than that of the perforated material and the absorber, so that the affected part is formed by a portion that is outside the peripheries of the perforated material and the absorber. It becomes possible to adhere and fix to.
As the pressure-sensitive adhesive covering the bottom surface of the cover material, the same material as the silicone resin covering the perforated material and the absorber can be used. For example, it contains an acrylic pressure-sensitive adhesive, a rubber pressure-sensitive adhesive, and a water-absorbing polymer. It is also possible to use an adhesive other than a silicone resin such as a so-called hydrocolloid adhesive.
Examples of the material for the cover material include non-woven fabrics, knitted fabrics, woven fabrics, fibrous sheets such as nets, synthetic resin films, foams, etc., and the degree of liquid permeability can be controlled by appropriate selection of these materials. it can.
（孔開き材料と吸収体へのシリコーン樹脂の被覆）
本発明の傷手当用品は、孔開き材料の少なくとも底面が、貫通孔全部が塞がれることがないように貫通孔の少なくとも一部を残してシリコーン樹脂で被覆される。孔開き材料の底面側から吸収体内部へ液体が通過するのであれば孔開き材料の貫通孔の一部がシリコーン樹脂で塞がれても良いが、貫通孔の６０％以上がシリコーン樹脂で塞がれることなく貫通部分を残していることが好ましく、貫通孔の８０％以上が残っていることが更に好ましく、貫通孔の全部がシリコーン樹脂で塞がれずに残っていることが特に好ましい。孔開き材料の貫通孔がシリコーン樹脂により塞がれないため、孔開き材料の底面側から吸収体内部への滲出液の通過が可能となる。
孔開き材料は、傷への固着性を低減するために、その上面もシリコーン樹脂で被覆されることが好ましく、貫通孔の内周面を含めた孔開き材料の全表面をシリコーン樹脂で被覆されることがより好ましい。
また本発明の傷手当用品は、吸収体の孔開き材料の貫通孔と対向する部分の一部が、シリコーン樹脂で被覆される。ただし、吸収体をシリコーン樹脂で被覆をしたとしても、開き材料の底面側から吸収体内部へ血液、滲出液等の液体が通過し得ることが必要である。そのような液体の通過を可能とするためには、吸収体の孔開き材料の貫通孔と対向する部分が、液体が通過することを阻害しない程度にシリコーン樹脂で被覆されていることが好ましい。
吸収体を被覆するシリコーン樹脂の量は、５〜１５０ｇ／ｍ2である事が好ましく、１５〜１００ｇ／ｍ2が更に好ましい。吸収体を被覆するシリコーン樹脂の量が５ｇ／ｍ2より少ないと、吸収体と傷との固着を防ぐことが困難になり、１５０ｇ／ｍ2より多いと、シリコーン樹脂が吸収体の空孔部分を塞いでしまい滲出液の吸収が効率良く行なわれない可能性がある。
(Perforated material and silicone resin coating on absorber)
In the wound dressing of the present invention, at least the bottom surface of the perforated material is covered with a silicone resin so that at least a part of the through hole is not closed so that the entire through hole is not blocked. If the liquid passes from the bottom surface side of the perforated material to the inside of the absorber, a part of the perforated hole of the perforated material may be blocked with silicone resin, but 60% or more of the perforated material is blocked with silicone resin. It is preferable to leave the penetrating part without peeling off, more preferably 80% or more of the through hole remains, and it is particularly preferable that the entire through hole remains without being blocked by the silicone resin. Since the through hole of the perforated material is not blocked by the silicone resin, the exudate can pass from the bottom surface side of the perforated material into the absorbent body.
The top surface of the perforated material is preferably coated with silicone resin in order to reduce adhesion to scratches, and the entire surface of the perforated material including the inner peripheral surface of the through hole is coated with silicone resin. More preferably.
In the wound care product of the present invention, a part of the portion of the absorbent body facing the through hole of the perforated material is covered with a silicone resin. However, even if the absorber is coated with a silicone resin, it is necessary that liquid such as blood and exudate can pass from the bottom surface side of the opening material into the absorber. In order to allow such a liquid to pass, it is preferable that a portion of the absorbent body facing the through hole of the perforated material is coated with a silicone resin to the extent that the liquid does not hinder the passage.
The amount of the silicone resin for covering the absorbent body, it is preferably from 5 to 150 g / m 2, more preferably 15 to 100 / m 2. If the amount of the silicone resin covering the absorber is less than 5 g / m 2, it will be difficult to prevent the absorber from being fixed to the scratch. If it exceeds 150 g / m 2 , the silicone resin will become a void portion of the absorber. There is a possibility that exudate may not be absorbed efficiently.
また、孔開き材料と吸収体とを、孔開き材料の上面に位置するシリコーン樹脂により接着することが、傷への固着性及び製造上の観点から好ましい。孔開き材料と吸収体とをシリコーン樹脂で接着する態様としては、シリコーン樹脂を孔開き材料の底面から内部に浸透させ孔開き材料の上面に至らせ、そのシリコーン樹脂により接着する態様を用いることが好ましい。このような態様によれば、孔開き材料のシリコーン樹脂による被覆と、孔開き材料と吸収体の一体化とを同時に行うことができ、製造上有利である。
なお、孔開き材料と吸収体の両方を含めた傷手当用品全体に付着させるシリコーン樹脂の量は、１５０〜３５０ｇ／ｍ2であることが好ましく、１７０〜２５０ｇ／ｍ2が更に好ましい。１５０ｇ／ｍ2より少ないと、傷との固着を防ぐことが困難になり、孔開き材料の内部にシリコーン樹脂を浸透させ孔開き材料と吸収体とを接着することが困難となる。また、３５０ｇ／ｍ2より多いと、シリコーン樹脂が孔開き材料の貫通孔と吸収体の空孔部分を塞いでしまい滲出液の吸収が効率良く行なわれなくなる可能性がある。
本発明の傷手当用品の粘着力は、０．１〜１．５Ｎ/２５ｍｍであることが好ましく、０．１５〜１．２Ｎ/２５ｍｍであることが更に好ましい。傷手当用品の粘着力が０．１Ｎ/２５ｍｍより低いと患部への密着性が損なわれる恐れがあり、１．５Ｎ/２５ｍｍより高いと、傷手当用品の交換時に創傷面を損傷してしまう恐れがある。
In addition, it is preferable to bond the perforated material and the absorbent body with a silicone resin located on the upper surface of the perforated material from the viewpoint of adhesion to scratches and manufacturing. As an aspect in which the perforated material and the absorbent body are adhered with the silicone resin, an aspect in which the silicone resin penetrates from the bottom surface of the perforated material to the inside and reaches the upper surface of the perforated material and is adhered by the silicone resin is used. preferable. According to such an embodiment, the perforated material can be coated with the silicone resin and the perforated material and the absorber can be integrated at the same time, which is advantageous in manufacturing.
The amount of the silicone resin to be adhered to the wound dressing entire article, including both the perforated material absorber is preferably 150 to 350 g / m 2, more preferably 170~250g / m 2. When the amount is less than 150 g / m 2, it is difficult to prevent sticking to the scratch, and it is difficult to allow the silicone resin to penetrate into the perforated material and bond the perforated material and the absorbent body. On the other hand, if it is more than 350 g / m 2 , the silicone resin may block the through-holes of the perforated material and the pores of the absorber, and the exudate may not be absorbed efficiently.
The adhesive force of the wound dressing of the present invention is preferably 0.1 to 1.5 N / 25 mm, and more preferably 0.15 to 1.2 N / 25 mm. If the adhesive force of the wound dressing product is lower than 0.1 N / 25 mm, the adhesion to the affected area may be impaired. If it is higher than 1.5 N / 25 mm, the wound surface may be damaged when the wound dressing product is replaced. There is.
以下に、実施例に基づいて本発明を更に詳細に説明するが、本発明はこれらに限定されない。
また、本発明の傷手当用品に関する特性は、以下の方法により測定した。
Hereinafter, the present invention will be described in more detail based on examples, but the present invention is not limited thereto.
Moreover, the characteristic regarding the wound care product of this invention was measured with the following method.
〔孔開き材料の貫通孔平均断面積（単位：ｍｍ2）〕
孔開き材料の底面を垂直方向（底面と直交する方向）から顕微鏡にて観察し、５個の貫通孔の断面積を測定して、その平均値を求める。
[Average cross-sectional area of the through-hole of the perforated material (unit: mm 2 )]
The bottom surface of the perforated material is observed with a microscope from the vertical direction (direction orthogonal to the bottom surface), the cross-sectional areas of the five through holes are measured, and the average value is obtained.
〔孔開き材料の開孔率（単位：％）〕
孔開き材料の底面を垂直方向（底面と直交する方向）から顕微鏡にて観察し、一定面積内で何個の孔が存在するか数え、上記で算出した断面積の平均値を基に求める。
[Aperture rate of perforated material (unit:%)]
The bottom surface of the perforated material is observed with a microscope from the vertical direction (direction perpendicular to the bottom surface), the number of holes present in a certain area is counted, and the average value of the cross-sectional areas calculated above is obtained.
〔孔開き材料の厚さ（単位：ｍｍ）〕
ＪＩＳ Ｌ １０９６「一般織物試験方法」に準じて、シリコーン樹脂を被覆する前の厚さを測定する。
[Thickness of perforated material (unit: mm)]
According to JIS L 1096 “General Textile Test Method”, the thickness before coating with the silicone resin is measured.
〔傷手当用品の粘着力（単位：Ｎ／２５ｍｍ）〕
ＪＩＳ Ｚ ０２３７-２０００「１８０度引き剥がし粘着力」に準じて測定する。ただし、被着体にはベークライト板を使用する。
[Adhesive strength of wound dressing (unit: N / 25mm)]
Measured according to JIS Z 0237-2000 “180 degree peeling adhesion”. However, a bakelite plate is used for the adherend.
〔吸収体のシリコーン樹脂被覆量（ｇ／ｍ2）〕
傷手当用品を作製する前に、シリコーン樹脂が被覆される前の吸収体の重量を予め測定しておく（Ｗ１）。傷手当用品を作製後、孔開き材料と吸収体を分離し、再度重量を測定する（Ｗ２）。Ｗ１とＷ２の重量変位から単位面積あたりの吸収体のシリコーン樹脂被覆量（ｇ／ｍ2）を算出する。
[Silicone resin coating amount of absorber (g / m 2 )]
Before producing the wound care product, the weight of the absorbent body before being coated with the silicone resin is measured in advance (W1). After producing the wound dressing, the perforated material and the absorbent are separated and the weight is measured again (W2). The silicone resin coating amount (g / m 2 ) of the absorber per unit area is calculated from the weight displacement of W1 and W2.
〔実施例１〕
図４で説明したＰ１、Ｐ２Ａ、Ｐ３の工程を経る製造方法に従い作製した。具体的には、次の通りである。
ビニル基置換ポリジメチルシロキサン、オルガノハイドロジェンポリシロキサン及び白金触媒を主体とする２成分型の付加反応型シリコーン樹脂（ダウコーニング社製、商品名「ＤＯＷ ＣＯＲＮＩＮＧ ７−９８００」）を混合し、得られた混合液をシリコーン剥離シートに一定の厚さで塗工した。次いで、塗工したシリコーン樹脂上に、ポリエステル製のトリコット編かなる孔開き材料と、レーヨン繊維等を含む不織布からなる吸収体を供給する。それから、シリコーン樹脂、孔開き材料、及び吸収体からなる積層体に一定の荷重を加え、孔開き材料と吸収体をシリコーン樹脂で被覆すると共に、孔開き材料と吸収体をシリコーン樹脂により接着する。その後、１１０℃で２分間加熱し、シリコーン樹脂を硬化させ、本発明の傷手当用品を得た。得られた傷手当用品の孔開き材料側からの拡大図を図６に示す。図６によれば、吸収体の不織布の一部にシリコーン樹脂がからんで付着し、残りの部分には、シリコーン樹脂が付着せずに液体が通過可能な状態となっていることがわかる。
[Example 1]
It produced according to the manufacturing method which passed through the process of P1, P2A, and P3 demonstrated in FIG. Specifically, it is as follows.
It is obtained by mixing a vinyl group-substituted polydimethylsiloxane, an organohydrogenpolysiloxane, and a two-component addition-reactive silicone resin (trade name “DOW CORNING 7-9800”, manufactured by Dow Corning) mainly composed of a platinum catalyst. The mixed solution was applied to a silicone release sheet with a certain thickness. Next, an absorbent body made of a non-woven fabric including a perforated material made of polyester tricot and a rayon fiber is supplied onto the coated silicone resin. Then, a certain load is applied to the laminate composed of the silicone resin, the apertured material, and the absorber to coat the apertured material and the absorber with the silicone resin, and the apertured material and the absorber are bonded to each other with the silicone resin. Then, it heated at 110 degreeC for 2 minute (s), the silicone resin was hardened, and the wound dressing article of this invention was obtained. An enlarged view from the perforated material side of the obtained wound dressing is shown in FIG. According to FIG. 6, it can be seen that the silicone resin is entangled and adhered to a part of the nonwoven fabric of the absorbent body, and the liquid can pass through the remaining part without the silicone resin being adhered.
［実施例２］
吸収体をポリウレタンフォームに代える以外は、実施例１と同様の方法で傷手当用品を得た。得られた傷手当用品の孔開き材料側からの拡大図を図７に示す。図７においても、吸収体のポリウレタンフォームの一部にシリコーン樹脂がからんで付着している状態がわかる。
[Example 2]
A wound dressing product was obtained in the same manner as in Example 1 except that the absorbent body was replaced with polyurethane foam. FIG. 7 shows an enlarged view from the perforated material side of the obtained wound dressing. Also in FIG. 7, it can be seen that the silicone resin is entangled and adhered to a part of the polyurethane foam of the absorber.
［比較例1］
孔開き材料の底面にのみシリコーン樹脂を被覆する以外は、実施例１と同じ構成で傷手当用品を作成した。即ち、比較例１の傷手当用品は、吸収体の孔開き材料の貫通孔と対向する部分がシリコーン樹脂で被覆されていない。得られた傷手当用品の孔開き材料側からの拡大図を図８に示す。
[Comparative Example 1]
A wound dressing was prepared with the same structure as in Example 1 except that the silicone resin was coated only on the bottom surface of the perforated material. That is, in the wound care product of Comparative Example 1, the portion of the absorbent body facing the through hole of the perforated material is not covered with the silicone resin. An enlarged view from the perforated material side of the obtained wound dressing is shown in FIG.
実施例と比較例の評価結果を表１に示す。 Table 1 shows the evaluation results of Examples and Comparative Examples.
上記の実施例１と比較例１で得られた傷手当用品を用い、吸収体の孔開き材料の貫通孔と対向する部分の一部をシリコーン樹脂で被覆することにより、生体組織との固着性が改善されるのかどうかに関して次の評価を行った。 Using the wound care product obtained in Example 1 and Comparative Example 1 above, by covering a part of the portion of the absorbent body facing the through hole of the perforated material with silicone resin, adhesion to living tissue The following evaluation was made as to whether or not
〔固着性評価〕
６週齢のオスＳＤラットの左側腹部に直径３ｃｍの全層皮膚欠損層を作製する。作製した傷部に滅菌済みの傷手当用品を被覆し、その上から弾性包帯を巻いて固定する。傷を作製してから２日後、９日後に傷から傷手当用品を剥離し、その固着状況を観察する。
[Evaluation of adhesiveness]
A full-thickness skin defect layer having a diameter of 3 cm is prepared on the left flank of a 6-week-old male SD rat. The prepared wound is covered with a sterilized wound dressing, and an elastic bandage is wound around it and fixed. The wound dressing is peeled from the wound two days after the wound is made, and the sticking state is observed after nine days.
（比較例１の結果）
比較例１で得られた傷手当用品では、２日後、孔開き材料のシリコーン樹脂被覆面では固着は見られなかったものの、孔開き材料の貫通孔部分で軽い固着を生じた。また剥離後の創面を観察すると創面が孔開き材料の形状に沿って凹凸を生じている様子が観察できた。
この結果は、ＳＤラットの創傷部の肉様膜組織が孔開き材料の貫通孔から侵入し吸収体に固着したために生じたものと推測される。９日後では、さらに強い固着を孔開き材料の貫通孔部分で生じた。傷手当用品を創面から引き剥がしたところ、創面から多量の出血が確認された。この結果は、２日後の場合と同様に新生した肉芽組織が貫通孔部から侵入し、吸収体の繊維を取り込み固着したために生じたものと推測される。結果を図９に示す。
(Results of Comparative Example 1)
In the wound dressing product obtained in Comparative Example 1, after 2 days, no fixing was observed on the silicone resin-coated surface of the perforated material, but light adhering occurred at the through hole portion of the perforated material. Moreover, when the wound surface after peeling was observed, it was observed that the wound surface was uneven along the shape of the perforated material.
This result is presumed to have occurred because the fleshy membrane tissue of the wound part of the SD rat entered through the through hole of the perforated material and was fixed to the absorber. After 9 days, stronger sticking occurred in the through-hole portion of the perforated material. When the wound dressing was removed from the wound surface, a large amount of bleeding was confirmed from the wound surface. This result is presumed to be caused by the newly formed granulation tissue entering from the through-hole portion and taking in and fixing the fibers of the absorber as in the case of 2 days later. The results are shown in FIG.
（実施例１の結果）
一方、実施例１で得られた傷手当用品では、２日後、全く固着を生じることなく剥離することができた。剥離後の創面も全く凹凸を生じていない。９日後では、孔開き材料の貫通孔部分で軽い固着を生じたものの、剥離後の創面からの出血はほとんど確認できなかった。実施例１と比較例１との構成の違いは、吸収体の孔開き材料の貫通孔と対向する部分の一部をシリコーン樹脂で被覆する点である。従って、本願発明が肉様膜及び肉芽組織による固着に対し有効であることが確認された。結果を図１０に示す。
(Result of Example 1)
On the other hand, the wound dressing product obtained in Example 1 could be peeled off after 2 days without causing any sticking. The wound surface after peeling is not uneven at all. After 9 days, although light fixation occurred at the through-hole portion of the perforated material, bleeding from the wound surface after peeling was hardly confirmed. The difference in configuration between Example 1 and Comparative Example 1 is that a part of the portion of the absorbent body facing the through hole of the perforated material is covered with a silicone resin. Therefore, it was confirmed that this invention is effective with respect to adhesion | attachment by a meat-like film | membrane and a granulation structure | tissue. The results are shown in FIG.
１０ 傷手当用品
２０ 孔開き材料
２１ 貫通孔
３０ 吸収体
３１ 貫通孔と対向する部分
４０，５２ シリコーン樹脂
５０，５１ カバー材
６０ 剥離シート
７０ 荷重
DESCRIPTION OF SYMBOLS 10 Wound care product 20 Perforated material 21 Through-hole 30 Absorber 31 Portion facing through-hole 40, 52 Silicone resin 50, 51 Cover material 60 Release sheet 70 Load
Claims (10)
孔開き材料の少なくとも底面が、貫通孔の全部が塞がれることがないように貫通孔の少なくとも一部を残してシリコーン樹脂で被覆され、
吸収体の孔開き材料の貫通孔と対向する部分の一部が、シリコーン樹脂で被覆され、
孔開き材料の底面側から吸収体内部へ液体が通過し得るようにしたことを特徴とする傷手当用品。 In a wound dressing product comprising a perforated material having a top surface and a bottom surface and having a plurality of through holes, and an absorber disposed on the top surface of the perforated material,
At least the bottom surface of the perforated material is covered with a silicone resin leaving at least a part of the through hole so that the entire through hole is not blocked,
Part of the portion of the absorbent body facing the through hole of the perforated material is coated with silicone resin,
A wound dressing product characterized in that liquid can pass from the bottom side of the perforated material into the absorbent body.
孔開き材料の上面及び底面が、貫通孔の全部が塞がれることがないように貫通孔の少なくとも一部を残してシリコーン樹脂で被覆され、
吸収体の孔開き材料の貫通孔と対向する部分の一部が、シリコーン樹脂で被覆され、
孔開き材料と吸収体とが、孔開き材料の上面に位置するシリコーン樹脂により接着され、孔開き材料の底面側から吸収体内部へ液体が通過し得るようにしたことを特徴とする傷手当用品。 In a wound dressing product comprising a perforated material having a top surface and a bottom surface and having a plurality of through holes, and an absorber disposed on the top surface of the perforated material,
The top and bottom surfaces of the perforated material are covered with a silicone resin leaving at least a part of the through hole so that the entire through hole is not blocked,
Part of the portion of the absorbent body facing the through hole of the perforated material is coated with silicone resin,
A wound dressing product characterized in that the perforated material and the absorbent body are bonded by a silicone resin located on the upper surface of the perforated material, so that liquid can pass from the bottom surface side of the perforated material into the absorbent body. .
（Ｐ１）剥離シートにシリコーン樹脂を塗工する工程、
（Ｐ２）硬化前のシリコーン樹脂塗工面に孔開き材料を載せ、孔開き材料の上面に吸収体を載せ、孔開き材料及び吸収体にシリコーン樹脂を被覆する工程、
（Ｐ３）シリコーン樹脂を加熱硬化させる工程、
からなることを特徴とする傷手当用品の製造方法。 A perforated material having a top surface and a bottom surface and having a plurality of through-holes, and an absorber disposed on the top surface of the perforated material, wherein at least the bottom surface of the perforated material is closed over all of the through-holes So that at least part of the through-holes is covered with silicone resin, and the part of the absorber facing the through-hole of the perforated material is partly covered with silicone resin and absorbed from the bottom side of the perforated material A method of manufacturing a wound care product that allows liquid to pass into the body,
(P1) A step of applying a silicone resin to the release sheet,
(P2) a step of placing a perforated material on the silicone resin coating surface before curing, placing an absorbent body on the top surface of the perforated material, and coating the perforated material and the absorbent body with a silicone resin;
(P3) heat curing the silicone resin,
A method of manufacturing a wound dressing product comprising the steps of:
（Ｐ１）剥離シートにシリコーン樹脂を塗工する工程、
（Ｐ２Ａ）硬化前のシリコーン樹脂塗工面に孔開き材料を載せ、孔開き材料の上面に吸収体を載せ、シリコーン樹脂を孔開き材料の底面から内部に浸透させ孔開き材料の上面に至らせることで孔開き材料と吸収体とをシリコーン樹脂により接着すると共に、孔開き材料及び吸収体にシリコーン樹脂を被覆する工程、
（Ｐ３）シリコーン樹脂を加熱硬化させる工程、
からなることを特徴とする傷手当用品の製造方法。 A perforated material having a top surface and a bottom surface and having a plurality of through-holes and an absorber disposed on the top surface of the perforated material, the top surface and the bottom surface of the perforated material are all blocked by the through-holes So that there is at least part of the through-holes and is covered with silicone resin, and part of the portion of the absorbent body facing the through-holes of the opening material is covered with silicone resin, Is a method of manufacturing a wound dressing article that is bonded by a silicone resin located on the top surface of the perforated material and allows liquid to pass from the bottom surface side of the perforated material into the absorber,
(P1) A step of applying a silicone resin to the release sheet,
(P2A) Putting a perforated material on the silicone resin coating surface before curing, placing an absorber on the upper surface of the perforated material, and allowing the silicone resin to penetrate inside from the bottom surface of the perforated material to reach the upper surface of the perforated material The step of adhering the perforated material and the absorbent body with a silicone resin and coating the perforated material and the absorbent body with the silicone resin,
(P3) heat curing the silicone resin,
A method of manufacturing a wound dressing product comprising the steps of:
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| DE3685227D1 (en) * | 1985-01-04 | 1992-06-17 | Squibb & Sons Inc | Wound bandage. |
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