JP4842686B2 - 皮膚外用剤 - Google Patents
皮膚外用剤 Download PDFInfo
- Publication number
- JP4842686B2 JP4842686B2 JP2006104725A JP2006104725A JP4842686B2 JP 4842686 B2 JP4842686 B2 JP 4842686B2 JP 2006104725 A JP2006104725 A JP 2006104725A JP 2006104725 A JP2006104725 A JP 2006104725A JP 4842686 B2 JP4842686 B2 JP 4842686B2
- Authority
- JP
- Japan
- Prior art keywords
- skin
- external preparation
- component
- present
- silicone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000002360 preparation method Methods 0.000 title claims description 23
- 230000000699 topical effect Effects 0.000 title description 3
- 229920001577 copolymer Polymers 0.000 claims description 9
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims description 8
- 229940047670 sodium acrylate Drugs 0.000 claims description 8
- XHZPRMZZQOIPDS-UHFFFAOYSA-N 2-Methyl-2-[(1-oxo-2-propenyl)amino]-1-propanesulfonic acid Chemical compound OS(=O)(=O)CC(C)(C)NC(=O)C=C XHZPRMZZQOIPDS-UHFFFAOYSA-N 0.000 claims description 6
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 4
- 125000000217 alkyl group Chemical group 0.000 claims description 3
- 125000004432 carbon atom Chemical group C* 0.000 claims description 3
- 229910052739 hydrogen Inorganic materials 0.000 claims description 3
- 239000001257 hydrogen Substances 0.000 claims description 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 2
- 229920001296 polysiloxane Polymers 0.000 description 16
- 238000003860 storage Methods 0.000 description 11
- 239000000203 mixture Substances 0.000 description 9
- 238000002156 mixing Methods 0.000 description 7
- 239000006071 cream Substances 0.000 description 6
- 239000002537 cosmetic Substances 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 5
- 229920002545 silicone oil Polymers 0.000 description 5
- 238000003892 spreading Methods 0.000 description 5
- 229920002125 Sokalan® Polymers 0.000 description 4
- 150000001298 alcohols Chemical class 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 239000000839 emulsion Substances 0.000 description 4
- 238000011156 evaluation Methods 0.000 description 4
- 239000003205 fragrance Substances 0.000 description 4
- 230000001771 impaired effect Effects 0.000 description 4
- 239000004094 surface-active agent Substances 0.000 description 4
- 239000002562 thickening agent Substances 0.000 description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 description 2
- 241000272185 Falco Species 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- KGLAXXUXWSFQMO-UHFFFAOYSA-N [Na].C(C=C)(=O)C(N(C)C)CS(=O)(=O)O Chemical compound [Na].C(C=C)(=O)C(N(C)C)CS(=O)(=O)O KGLAXXUXWSFQMO-UHFFFAOYSA-N 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- -1 gums Substances 0.000 description 2
- 239000000419 plant extract Substances 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 230000001953 sensory effect Effects 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 description 1
- DGSZGZSCHSQXFV-UHFFFAOYSA-N 2,3-bis(2-ethylhexanoyloxy)propyl 2-ethylhexanoate Chemical compound CCCCC(CC)C(=O)OCC(OC(=O)C(CC)CCCC)COC(=O)C(CC)CCCC DGSZGZSCHSQXFV-UHFFFAOYSA-N 0.000 description 1
- IRLPACMLTUPBCL-KQYNXXCUSA-N 5'-adenylyl sulfate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(=O)OS(O)(=O)=O)[C@@H](O)[C@H]1O IRLPACMLTUPBCL-KQYNXXCUSA-N 0.000 description 1
- NWGKJDSIEKMTRX-AAZCQSIUSA-N Sorbitan monooleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-AAZCQSIUSA-N 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 239000002280 amphoteric surfactant Substances 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000008406 cosmetic ingredient Substances 0.000 description 1
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 239000008269 hand cream Substances 0.000 description 1
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 229920005573 silicon-containing polymer Polymers 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 229950004959 sorbitan oleate Drugs 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- WNIFXKPDILJURQ-UHFFFAOYSA-N stearyl glycyrrhizinate Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C)CCC(C(=O)OCCCCCCCCCCCCCCCCCC)(C)CC5C4=CC(=O)C3C21C WNIFXKPDILJURQ-UHFFFAOYSA-N 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Description
その中でも、重合度として、nが2000〜5000であると仕上がりの滑らかさの面で特に好ましい。
20名の被験者によって皮膚外用剤(クリーム)の試料を顔に塗布した。その後被験者本人が、のびの良さ、べたつきの無さ、しっとり感の項目について官能評価し、平均評価点を求めた。評価基準は、以下の通りである。
3:良好
2:やや悪い
1:悪い
皮膚外用剤(クリーム)の試料を試験管に入れ、40℃、3000rpmの条件で30分間及び1時間遠心分離機にかけた。その後の状態を観察し評価した。評価基準は以下の通りである。
△:30分で変化なし
×:分離、沈殿等変化あり
表1に示した処方の皮膚外用剤(クリーム)を常法により作製し、前記各試験を実施した。その結果を表1に併せて示す。
(A)SIMULGEL EG(商品名) SEPPIC社製 2.5%
(B)高重合ジメチコノール(重合度3000) 5.0
(C)ポリエーテル変性シリコーン 7.0
(BY11−030(商品名) 東レ・ダウコーニング社製、50%液)
グリセリン 5.0
メチルフェニルポリシロキサン 7.0
スクワラン 3.0
ジプロピレングリコール 5.0
キサンタンガム 0.05
2−エチルヘキサン酸トリグリセリド 3.0
ビタミンE 0.05
グリチルリチン酸ステアリル 0.1
クエン酸 適 量
クエン酸ナトリウム 適 量
混合植物抽出液 0.5
(ファルコレックスBX32(商品名) 一丸ファルコス社製)
混合植物抽出液 0.5
(ファルコレックスBX52(商品名) 一丸ファルコス社製)
香料 0.3
精製水 残 量
Claims (3)
- 一般式(2)中のnが、2000〜3000である請求項1記載の皮膚外用剤。
- 成分(A)、(B)及び(C)の含有量が、成分(A)は0.03〜3.0質量%、成分(B)は0.5〜10.0質量%、成分(C)は0.1〜5.0質量%である請求項1又は2記載の皮膚外用剤。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006104725A JP4842686B2 (ja) | 2006-04-05 | 2006-04-05 | 皮膚外用剤 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006104725A JP4842686B2 (ja) | 2006-04-05 | 2006-04-05 | 皮膚外用剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007277142A JP2007277142A (ja) | 2007-10-25 |
JP4842686B2 true JP4842686B2 (ja) | 2011-12-21 |
Family
ID=38678976
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006104725A Expired - Fee Related JP4842686B2 (ja) | 2006-04-05 | 2006-04-05 | 皮膚外用剤 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP4842686B2 (ja) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4854051B2 (ja) | 2009-03-30 | 2012-01-11 | 株式会社 資生堂 | 水中油型乳化組成物 |
US8933134B2 (en) | 2010-06-09 | 2015-01-13 | L'oreal | Compositions containing agar and a softening agent |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2525194B2 (ja) * | 1986-09-02 | 1996-08-14 | 株式会社資生堂 | 皮膚化粧料 |
US5302382A (en) * | 1993-06-03 | 1994-04-12 | Dow Corning Corporation | Silicone containing personal care products |
JP3580384B2 (ja) * | 1995-03-31 | 2004-10-20 | 株式会社資生堂 | 乳化化粧料 |
JP3586852B2 (ja) * | 1996-03-27 | 2004-11-10 | 株式会社資生堂 | 毛髪化粧料 |
JP3644565B2 (ja) * | 1996-11-12 | 2005-04-27 | ポーラ化成工業株式会社 | W/o型乳化化粧料 |
JP2000034215A (ja) * | 1998-07-17 | 2000-02-02 | Shiseido Co Ltd | 皮膚外用剤 |
JP2003055141A (ja) * | 2001-08-06 | 2003-02-26 | Kose Corp | 油中水型乳化化粧料 |
JP4639053B2 (ja) * | 2003-03-12 | 2011-02-23 | 花王株式会社 | 制汗デオドラントスプレー組成物 |
JP4110407B2 (ja) * | 2003-05-30 | 2008-07-02 | ライオン株式会社 | 毛髪化粧料 |
JP2005179338A (ja) * | 2003-11-28 | 2005-07-07 | Kose Corp | 整髪料 |
JP4570905B2 (ja) * | 2004-05-17 | 2010-10-27 | 株式会社資生堂 | 皮膚外用剤 |
JP4688671B2 (ja) * | 2005-12-20 | 2011-05-25 | 株式会社資生堂 | 皮膚化粧料 |
-
2006
- 2006-04-05 JP JP2006104725A patent/JP4842686B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2007277142A (ja) | 2007-10-25 |
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