JP4588730B2 - 多基質バイオチップユニット - Google Patents
多基質バイオチップユニット Download PDFInfo
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- JP4588730B2 JP4588730B2 JP2007042089A JP2007042089A JP4588730B2 JP 4588730 B2 JP4588730 B2 JP 4588730B2 JP 2007042089 A JP2007042089 A JP 2007042089A JP 2007042089 A JP2007042089 A JP 2007042089A JP 4588730 B2 JP4588730 B2 JP 4588730B2
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/56—Means for indicating position of a recipient or sample in an array
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00545—Colours
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00547—Bar codes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
- B01J2219/00576—Chemical means fluorophore
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0858—Side walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Description
Claims (10)
- 基質への分析対象の結合を光学的に検出するための分析装置であって、
少なくとも1つの空洞を有するハウジングと、前記空洞内に少なくとも部分的に配置される多基質チップとを含み、
前記多基質チップが、所定の位置に複数の基質を含み、
前記多基質チップが担体を備え、該担体上にマトリックス層がコーティングされ、該マトリックス層は、アガロース、ゼラチン、またはポリアクリルアミドからなり、且つ、複数の架橋剤がマトリックス層全体に埋め込まれ、
前記複数の基質のうちの少なくとも1つが、分子鎖を介してマトリックス層に結合されており、マトリックス層を別個の所定の位置で複数の基質に接触させることにより、別個の所定の位置での同じマトリックス層上への複数の別個の基質の固定化が可能となるように、前記複数の架橋剤がマトリックス層全体に埋めこまれている、分析装置。 - 前記マトリックスが少なくとも2つの層から形成される、請求項1に記載の分析装置。
- 前記マトリックスが、バッファ、湿潤剤、遮光剤、および界面活性剤から成るグループから選択される少なくとも1つの添加物を含む、請求項2に記載の分析装置。
- 前記架橋剤が、10−5M以下のKDでビオチンに結合する分子を含む、請求項3に記載の分析装置。
- 前記ハウジングに結合したベース要素をさらに含み、前記ハウジングが第1の幅を有し、かつ前記ベース要素が第2の幅を有し、前記第1の幅が前記第2の幅よりも小さい、請求項1に記載の分析装置。
- 前記ベース要素がガイド要素を有する、請求項4に記載の分析装置。
- 前記複数の基質が、前記多基質チップが実質的に水平方向の位置にあるときに、サンプル流体、試薬流体、洗浄流体、および検出流体から成るグループから選択される少なくとも1つの流体と接触させられる、請求項1に記載の分析装置。
- 前記複数の基質のうちの少なくとも1つが、サンプル流体からの分析対象と結合し、前記分析対象の結合が、前記多基質チップが実質的に水平方向の位置にあるときに検出される、請求項7に記載の分析装置。
- 前記空洞が開放型の空洞である、請求項1に記載の分析装置。
- 請求項1に記載の分析装置を複数含み、前記複数の分析装置は、第1の装置のベース要素が第2の装置のハウジング上に配置されるように積層されるマガジン。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2001/047991 WO2002057416A2 (en) | 2000-12-12 | 2001-12-11 | Improved biochip |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003551588A Division JP3940398B2 (ja) | 2001-12-11 | 2002-01-24 | 多基質バイオチップユニット |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007163514A JP2007163514A (ja) | 2007-06-28 |
JP4588730B2 true JP4588730B2 (ja) | 2010-12-01 |
Family
ID=21743111
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003551588A Expired - Fee Related JP3940398B2 (ja) | 2001-12-11 | 2002-01-24 | 多基質バイオチップユニット |
JP2007042089A Expired - Fee Related JP4588730B2 (ja) | 2001-12-11 | 2007-02-22 | 多基質バイオチップユニット |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003551588A Expired - Fee Related JP3940398B2 (ja) | 2001-12-11 | 2002-01-24 | 多基質バイオチップユニット |
Country Status (7)
Country | Link |
---|---|
US (2) | US20050221283A1 (ja) |
EP (1) | EP1454177B1 (ja) |
JP (2) | JP3940398B2 (ja) |
AT (1) | ATE359534T1 (ja) |
AU (1) | AU2002248414A1 (ja) |
DE (1) | DE60219517T2 (ja) |
WO (1) | WO2003050591A1 (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7273591B2 (en) * | 2003-08-12 | 2007-09-25 | Idexx Laboratories, Inc. | Slide cartridge and reagent test slides for use with a chemical analyzer, and chemical analyzer for same |
US7588733B2 (en) | 2003-12-04 | 2009-09-15 | Idexx Laboratories, Inc. | Retaining clip for reagent test slides |
EP1935992A3 (en) | 2003-12-23 | 2008-12-03 | Autogenomics, Inc. | Multiplexed nucleic acid analysis with high specificity for human papilloma virus |
JP4628369B2 (ja) | 2003-12-23 | 2011-02-09 | オウトジエノミクス・インコーポレーテツド | 高感度核酸多重解析法 |
JP4955244B2 (ja) * | 2005-09-27 | 2012-06-20 | 横河電機株式会社 | バイオチップ読み取り装置およびバイオチップ読み取り方法 |
JP4711125B2 (ja) * | 2005-09-27 | 2011-06-29 | 横河電機株式会社 | バイオチップ、バイオチップ読み取り装置、およびバイオチップ読み取り方法 |
EP2176647B1 (en) * | 2007-07-27 | 2013-05-15 | Koninklijke Philips Electronics N.V. | Method and system for imaging samples |
KR101510351B1 (ko) | 2009-02-17 | 2015-04-06 | 삼성전자주식회사 | 마이크로어레이 및 마이크로어레이 신호를 분석하는 방법 |
US10551376B2 (en) | 2013-02-01 | 2020-02-04 | The General Hospital Corporation | Capture and release of particles from liquid samples |
WO2017074815A1 (en) | 2015-10-26 | 2017-05-04 | Idexx Laboratories, Inc. | Hematology test slide |
JPWO2022163124A1 (ja) * | 2021-01-29 | 2022-08-04 |
Citations (4)
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WO2000037934A1 (en) * | 1998-12-22 | 2000-06-29 | Toxin Alert, Inc. | Method and apparatus for selective biological material detection |
WO2000053310A1 (fr) * | 1999-03-08 | 2000-09-14 | Commissariat A L'energie Atomique | Procede de realisation d'une matrice de sequences de molecules chimiques ou biologiques pour dispositif d'analyse chimique ou biologique |
WO2001006496A1 (en) * | 1999-07-15 | 2001-01-25 | Nanogen, Inc. | Inorganic permeation layer for micro-electric device |
JP2004523749A (ja) * | 2000-12-12 | 2004-08-05 | オウトジエノミクス・インコーポレーテツド | 改良バイオチップ |
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-
2001
- 2001-12-11 US US10/433,766 patent/US20050221283A1/en not_active Abandoned
-
2002
- 2002-01-24 JP JP2003551588A patent/JP3940398B2/ja not_active Expired - Fee Related
- 2002-01-24 WO PCT/US2002/003917 patent/WO2003050591A1/en active IP Right Grant
- 2002-01-24 AT AT02717407T patent/ATE359534T1/de not_active IP Right Cessation
- 2002-01-24 AU AU2002248414A patent/AU2002248414A1/en not_active Abandoned
- 2002-01-24 EP EP02717407A patent/EP1454177B1/en not_active Expired - Lifetime
- 2002-01-24 DE DE60219517T patent/DE60219517T2/de not_active Expired - Lifetime
-
2007
- 2007-02-22 JP JP2007042089A patent/JP4588730B2/ja not_active Expired - Fee Related
-
2010
- 2010-08-27 US US12/870,337 patent/US20110086771A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2000037934A1 (en) * | 1998-12-22 | 2000-06-29 | Toxin Alert, Inc. | Method and apparatus for selective biological material detection |
WO2000053310A1 (fr) * | 1999-03-08 | 2000-09-14 | Commissariat A L'energie Atomique | Procede de realisation d'une matrice de sequences de molecules chimiques ou biologiques pour dispositif d'analyse chimique ou biologique |
WO2001006496A1 (en) * | 1999-07-15 | 2001-01-25 | Nanogen, Inc. | Inorganic permeation layer for micro-electric device |
JP2004523749A (ja) * | 2000-12-12 | 2004-08-05 | オウトジエノミクス・インコーポレーテツド | 改良バイオチップ |
Also Published As
Publication number | Publication date |
---|---|
AU2002248414A1 (en) | 2003-06-23 |
US20110086771A1 (en) | 2011-04-14 |
ATE359534T1 (de) | 2007-05-15 |
US20050221283A1 (en) | 2005-10-06 |
EP1454177A4 (en) | 2006-03-22 |
JP2007163514A (ja) | 2007-06-28 |
EP1454177B1 (en) | 2007-04-11 |
JP2005512097A (ja) | 2005-04-28 |
JP3940398B2 (ja) | 2007-07-04 |
EP1454177A1 (en) | 2004-09-08 |
DE60219517D1 (de) | 2007-05-24 |
DE60219517T2 (de) | 2008-01-03 |
WO2003050591A1 (en) | 2003-06-19 |
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