JP4560643B2 - 呼吸気ct画像による換気分布計測方法 - Google Patents
呼吸気ct画像による換気分布計測方法 Download PDFInfo
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- JP4560643B2 JP4560643B2 JP2004179618A JP2004179618A JP4560643B2 JP 4560643 B2 JP4560643 B2 JP 4560643B2 JP 2004179618 A JP2004179618 A JP 2004179618A JP 2004179618 A JP2004179618 A JP 2004179618A JP 4560643 B2 JP4560643 B2 JP 4560643B2
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- 238000009423 ventilation Methods 0.000 title claims description 50
- 230000000241 respiratory effect Effects 0.000 title claims description 15
- 238000000691 measurement method Methods 0.000 title claims description 5
- 210000004072 lung Anatomy 0.000 claims description 81
- 238000000034 method Methods 0.000 claims description 30
- 238000006073 displacement reaction Methods 0.000 claims description 28
- 210000004204 blood vessel Anatomy 0.000 claims description 4
- 238000011156 evaluation Methods 0.000 claims description 4
- 230000010354 integration Effects 0.000 claims description 4
- 210000004224 pleura Anatomy 0.000 claims description 3
- 238000005259 measurement Methods 0.000 claims description 2
- 238000002591 computed tomography Methods 0.000 description 44
- 238000010586 diagram Methods 0.000 description 5
- 230000029058 respiratory gaseous exchange Effects 0.000 description 5
- 230000004064 dysfunction Effects 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 239000003814 drug Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 238000002600 positron emission tomography Methods 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 238000004088 simulation Methods 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 2
- 230000003434 inspiratory effect Effects 0.000 description 2
- 238000002595 magnetic resonance imaging Methods 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000002685 pulmonary effect Effects 0.000 description 2
- 230000004202 respiratory function Effects 0.000 description 2
- 238000013125 spirometry Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 206010014561 Emphysema Diseases 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 description 1
- 230000005980 lung dysfunction Effects 0.000 description 1
- 230000004199 lung function Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000009206 nuclear medicine Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
Images
Landscapes
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Description
2 呼気時CT画像
3 平面画像
4 立体画像
5 容積減少部
6 容積変化が無い部分
7 容積増加部
Claims (5)
- 3次元的に撮像された肺の呼気時のCT画像および吸気時のCT画像より肺領域を抽出し、
非剛体レジストレーション手法を用いて前記呼気時のCT画像と前記吸気時のCT画像との間で、前記肺領域の位置合せを行ない、
該位置合せにより前記肺領域における変位ベクトル場を求め、
求められた前記変位ベクトル場の各点において発散を計算し、
計算された前記各点における前記発散に基づき前記肺の局所換気量を求めることを特徴とする呼吸気CT画像による換気分布計測方法。 - 前記局所換気量に基づき、前記肺の換気分布状態を求めることを特徴とする請求項1記載の呼吸気CT画像による換気分布計測方法。
- 前記発散の体積積分により前記肺の総換気量を求めることを特徴とする請求項1または2記載の呼吸気CT画像による換気分布計測方法。
- 前記非剛体レジストレーション手法が、前記位置合せをボクセルベースで行なって、前記変位ベクトル場を求めるボクセルベース非剛体レジストレーション手法であることを特徴とする請求項1〜3までのいずれか1項記載の呼吸気CT画像による換気分布計測方法。
- 前記ボクセルベース非剛体レジストレーション手法において用いられる評価関数は、前記変位ベクトル場の前記発散を記述する発散項を含み、該発散項は、肺実質のボクセルに対応するものに対しては負の所定の重みが与えられ、肺胸膜、血管のボクセルに対応するものには正の所定の重みが与えられることを特徴とする請求項4記載の呼吸気CT画像による換気分布計測方法。
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JP2004179618A JP4560643B2 (ja) | 2003-06-17 | 2004-06-17 | 呼吸気ct画像による換気分布計測方法 |
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JP2005028121A JP2005028121A (ja) | 2005-02-03 |
JP4560643B2 true JP4560643B2 (ja) | 2010-10-13 |
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Families Citing this family (23)
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CN101061508B (zh) * | 2004-11-17 | 2012-06-13 | 皇家飞利浦电子股份有限公司 | 改进的弹性图像重合功能 |
WO2007111207A1 (ja) * | 2006-03-16 | 2007-10-04 | Osaka University | 3次元スパイログラム計測方法及びコンピュータプログラム |
JP4709177B2 (ja) * | 2007-04-12 | 2011-06-22 | 富士フイルム株式会社 | 三次元画像処理装置および方法並びにプログラム |
WO2009078297A1 (ja) * | 2007-12-19 | 2009-06-25 | Konica Minolta Medical & Graphic, Inc. | 動態画像処理システム |
WO2009090894A1 (ja) * | 2008-01-15 | 2009-07-23 | Konica Minolta Medical & Graphic, Inc. | 動態画像診断支援システム |
JP5192354B2 (ja) * | 2008-11-04 | 2013-05-08 | 株式会社リガク | 領域特定方法、これを用いた容積計測方法、領域特定装置および領域特定プログラム |
WO2010086776A1 (en) | 2009-01-30 | 2010-08-05 | Koninklijke Philips Electronics N.V. | System for providing lung ventilation information |
JP5572440B2 (ja) | 2009-09-15 | 2014-08-13 | 富士フイルム株式会社 | 診断支援システム、診断支援プログラムおよび診断支援方法 |
JP5723541B2 (ja) | 2010-03-31 | 2015-05-27 | 富士フイルム株式会社 | 医用画像診断支援装置およびその作動方法、並びにプログラム |
JP4931027B2 (ja) | 2010-03-29 | 2012-05-16 | 富士フイルム株式会社 | 医用画像診断支援装置および方法、並びにプログラム |
JP5597429B2 (ja) | 2010-03-31 | 2014-10-01 | 富士フイルム株式会社 | 医用画像処理装置および方法、並びにプログラム |
JP5844187B2 (ja) * | 2012-03-23 | 2016-01-13 | 富士フイルム株式会社 | 画像解析装置および方法並びにプログラム |
NZ710964A (en) * | 2013-02-14 | 2019-03-29 | Fluidda Respi | Method for determining a respiratory condition based on functional respiratory imaging |
EP2982304B1 (en) * | 2013-04-05 | 2018-04-25 | Toshiba Medical Systems Corporation | Medical image processing apparatus and medical image processing method |
JP6184244B2 (ja) * | 2013-05-30 | 2017-08-23 | 東芝メディカルシステムズ株式会社 | 医用画像処理装置 |
US9760989B2 (en) * | 2014-05-15 | 2017-09-12 | Vida Diagnostics, Inc. | Visualization and quantification of lung disease utilizing image registration |
US10074207B2 (en) | 2014-05-19 | 2018-09-11 | Koninklijke Philips N.V. | Visualization of tissue of interest in contrast-enhanced image data |
EP3294136B1 (en) | 2015-05-08 | 2020-11-18 | Vida Diagnostics, Inc. | System for quantifying regional fissure features |
KR20170096088A (ko) | 2016-02-15 | 2017-08-23 | 삼성전자주식회사 | 영상처리장치, 영상처리방법 및 이를 기록한 기록매체 |
JP6686733B2 (ja) * | 2016-06-23 | 2020-04-22 | コニカミノルタ株式会社 | 動態解析システム |
EP4006836A1 (en) * | 2016-08-18 | 2022-06-01 | William Beaumont Hospital | System and method for determining respiratory induced blood mass change from 4d computed tomography |
JP6200618B1 (ja) * | 2017-05-18 | 2017-09-20 | Psp株式会社 | 医用画像診断支援システム及び装置、並びに、プログラム |
JP6436222B2 (ja) * | 2017-12-21 | 2018-12-12 | コニカミノルタ株式会社 | 動態画像解析装置 |
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