JP4491460B2 - 血液製剤から物質を除去するためのフィルター - Google Patents
血液製剤から物質を除去するためのフィルター Download PDFInfo
- Publication number
- JP4491460B2 JP4491460B2 JP2006526611A JP2006526611A JP4491460B2 JP 4491460 B2 JP4491460 B2 JP 4491460B2 JP 2006526611 A JP2006526611 A JP 2006526611A JP 2006526611 A JP2006526611 A JP 2006526611A JP 4491460 B2 JP4491460 B2 JP 4491460B2
- Authority
- JP
- Japan
- Prior art keywords
- filter
- web
- blood
- polymer
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
- A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0439—White blood cells; Leucocytes
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Filtering Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Processing Of Meat And Fish (AREA)
Description
新フィルター材料を用いた全血(WB)フィルターを、常用のフィルター材料で製造したフィルターと比較した。
PS−DVBマイクロスフェアをウェブ1g当り0.4gの量で使用し、実施例1に記載した新フィルター材料でフィルターを製造した。
Claims (8)
- −白血球除去に適する孔サイズを持つ繊維ウェブ少なくとも1種を含む多孔性要素;
−疎水性ポリマーのCWSTを増大させるために適する親水性ポリマーでコーティングされた疎水性ポリマーの繊維を含む該ウェブ;
を含む、血液製剤から白血球含有量の枯渇をさせるためのフィルター装置であって、
該ウェブが30μm以下の平均直径を有する吸着剤粒子をさらに含み、その粒子が繊維をコーティングしている親水性ポリマーによって該繊維に結合していること、
該ウェブが、吸着剤粒子を0.1〜10重量%で懸濁して含む親水性ポリマーの溶液に疎水性ポリマーの繊維ウェブを浸す(含浸する)ことによって得られること、
該ウェブが、繊維ウェブ材1g当り0.01〜0.5gの範囲の量で該粒子を含むこと、
および、該不織ウェブの繊維直径が、0.01〜5μmの範囲内であること
を特徴とする、フィルター装置。 - 該親水性コーティングポリマーが、酢酸ビニルとビニルピロリドンとの重合によって得られるコポリマーから選択される、請求項1に記載のフィルター装置。
- 該吸着剤粒子がアクリル酸ポリマー、ポリエステル、ポリアミド、ポリアクリルアミド及びポリスチレン−ジビニルベンゼンから構成される群から選択される材料から製造される、請求項1または2に記載のフィルター装置。
- 該疎水性ポリマーがポリエチレン、ポリプロピレン、酢酸セルロース、ポリアミド、アクリル樹脂、ポリアクリロニトリル、フッ化ポリビニリデン、ポリアラミド及びポリエステルから構成される群から選択される、請求項1〜3のいずれか一項に記載のフィルター装置。
- 該疎水性ポリマーがポリブチレンテレフタレートであり、該吸着剤粒子がポリアミド又はポリスチレン−ジビニルベンゼンポリマーから作られ、さらに、該繊維を少なくとも部分的にコーティングするポリビニルピロリドンによって疎水性繊維に結合されている、請求項1〜4のいずれか一項に記載のフィルター装置。
- 請求項1〜5のいずれか一項に記載のフィルターを通過させて血液製剤を供給することを含む、血液製剤から物質を除去する方法。
- 請求項1〜5のいずれか一項に記載のフィルターを含む血液精製装置。
- 請求項1〜5のいずれか一項に記載のフィルターを通過する第二のバッグに流通可能に連結した第一のバッグを含む、血液を白血球枯渇血液成分に分離するための血液バッグ装置からなる、請求項7に記載の血液精製装置。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03021435A EP1518573B1 (en) | 2003-09-23 | 2003-09-23 | Filter, purification device and method for the removal of substances from blood products |
PCT/EP2004/010618 WO2005028003A1 (en) | 2003-09-23 | 2004-09-22 | A filter for the removal of substances from blood products |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007505662A JP2007505662A (ja) | 2007-03-15 |
JP4491460B2 true JP4491460B2 (ja) | 2010-06-30 |
Family
ID=34178476
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006526611A Expired - Fee Related JP4491460B2 (ja) | 2003-09-23 | 2004-09-22 | 血液製剤から物質を除去するためのフィルター |
Country Status (8)
Country | Link |
---|---|
US (1) | US7524425B2 (ja) |
EP (1) | EP1518573B1 (ja) |
JP (1) | JP4491460B2 (ja) |
CN (1) | CN100500232C (ja) |
AT (1) | ATE337036T1 (ja) |
DE (1) | DE60307849T2 (ja) |
ES (1) | ES2268245T3 (ja) |
WO (1) | WO2005028003A1 (ja) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101842111A (zh) | 2007-08-31 | 2010-09-22 | 密执安州立大学董事会 | 选择性细胞隔离装置及其相关方法 |
DE102009006583A1 (de) * | 2009-01-29 | 2010-06-17 | Neenah Gessner Gmbh | Mehrlagiges Filtermaterial für die Flüssigkeitsfiltration |
BRPI1006674A2 (pt) * | 2009-04-07 | 2016-04-12 | 3M Innovative Properties Co | "mantas absorventes carregadas aprimoradas para filtração por gravidade" |
JP2014500735A (ja) | 2010-10-15 | 2014-01-16 | サイトフェリックス インコーポレイテッド | サイトフェレーシスカートリッジおよびその使用 |
WO2013106108A2 (en) | 2011-10-14 | 2013-07-18 | Cytopherx, Inc. | Cartridge and method for increasing myocardial function |
WO2014176573A1 (en) * | 2013-04-25 | 2014-10-30 | Perlstein Alan | Non-hemolyzing blood filter and methods for filtering blood without hemolysis |
US9968738B2 (en) | 2014-03-24 | 2018-05-15 | Fenwal, Inc. | Biological fluid filters with molded frame and methods for making such filters |
US10159778B2 (en) | 2014-03-24 | 2018-12-25 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
US9796166B2 (en) | 2014-03-24 | 2017-10-24 | Fenwal, Inc. | Flexible biological fluid filters |
US9782707B2 (en) | 2014-03-24 | 2017-10-10 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
US10376627B2 (en) | 2014-03-24 | 2019-08-13 | Fenwal, Inc. | Flexible biological fluid filters |
WO2015160392A1 (en) | 2014-04-16 | 2015-10-22 | Cummins Filtration Ip, Inc. | Tuning surface properties of melt blown polyester fibers by hydrolysis and solution grafting |
WO2016093999A1 (en) * | 2014-12-12 | 2016-06-16 | The Trustees Of The University Of Pennsylvania | Fluid separator for point of care molecular diagnostics |
KR101989901B1 (ko) | 2016-06-02 | 2019-06-17 | 주식회사 아모그린텍 | 필터여재, 이의 제조방법 및 이를 포함하는 필터모듈 |
CN106117580A (zh) * | 2016-06-23 | 2016-11-16 | 广州新克力生物科技有限公司 | 一种用于滤除白细胞的滤膜改性剂及其改性方法 |
CN106319966B (zh) * | 2016-08-18 | 2019-08-16 | 南京双威生物医学科技有限公司 | 一种白细胞滤膜的处理方法 |
EP3612247A1 (en) * | 2017-04-20 | 2020-02-26 | Fenwal, Inc. | Systems and methods for platelet filtration using an additive |
TWI715998B (zh) | 2019-01-28 | 2021-01-11 | 笙特科技股份有限公司 | 過濾材料及其製造方法 |
CN110787647B (zh) * | 2019-11-11 | 2024-01-19 | 上海输血技术有限公司 | 一种血小板去白细胞过滤膜及其制备方法 |
CN117982987B (zh) * | 2024-04-03 | 2024-06-18 | 四川厚浦生物科技有限公司 | 一种白细胞过滤材料及其制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9756A (en) | 1853-05-31 | Eibeplace and stove | ||
US4618533A (en) | 1984-11-30 | 1986-10-21 | Millipore Corporation | Porous membrane having hydrophilic surface and process |
IL88081A0 (en) | 1987-10-20 | 1989-06-30 | Pall Corp | Device and method for depletion of the leucocyte content of blood and blood components |
GB2231282B (en) | 1989-05-09 | 1993-08-04 | Pall Corp | Device and method for depletion of the leucocyte content of blood and blood components |
US5152905A (en) | 1989-09-12 | 1992-10-06 | Pall Corporation | Method for processing blood for human transfusion |
US5454946A (en) | 1991-07-22 | 1995-10-03 | Lydall, Inc. | Filter material for filtering leucocytes from blood |
JPH09508823A (ja) * | 1994-01-10 | 1997-09-09 | ヒマシュア,インコーポレイテッド | 血液からの白血球及びウイルス不活性化作用物質の除去装置とプロセス |
US5660731A (en) * | 1994-11-08 | 1997-08-26 | Pall Corporation | Filter for separating photoactive agent |
US20010009756A1 (en) * | 1998-01-06 | 2001-07-26 | Derek Hei | Flow devices for the reduction of compounds from biological compositions and methods of use |
US6337026B1 (en) | 1999-03-08 | 2002-01-08 | Whatman Hemasure, Inc. | Leukocyte reduction filtration media |
-
2003
- 2003-09-23 ES ES03021435T patent/ES2268245T3/es not_active Expired - Lifetime
- 2003-09-23 DE DE60307849T patent/DE60307849T2/de not_active Expired - Lifetime
- 2003-09-23 AT AT03021435T patent/ATE337036T1/de active
- 2003-09-23 EP EP03021435A patent/EP1518573B1/en not_active Expired - Lifetime
-
2004
- 2004-09-22 JP JP2006526611A patent/JP4491460B2/ja not_active Expired - Fee Related
- 2004-09-22 CN CNB2004800275672A patent/CN100500232C/zh not_active Expired - Fee Related
- 2004-09-22 WO PCT/EP2004/010618 patent/WO2005028003A1/en active Application Filing
- 2004-09-22 US US10/573,175 patent/US7524425B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE60307849T2 (de) | 2007-01-04 |
ATE337036T1 (de) | 2006-09-15 |
EP1518573A1 (en) | 2005-03-30 |
JP2007505662A (ja) | 2007-03-15 |
EP1518573B1 (en) | 2006-08-23 |
US7524425B2 (en) | 2009-04-28 |
CN1856332A (zh) | 2006-11-01 |
CN100500232C (zh) | 2009-06-17 |
US20080230475A1 (en) | 2008-09-25 |
WO2005028003A1 (en) | 2005-03-31 |
DE60307849D1 (de) | 2006-10-05 |
ES2268245T3 (es) | 2007-03-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4491460B2 (ja) | 血液製剤から物質を除去するためのフィルター | |
US5478470A (en) | Filter material for selectively removing leukocytes | |
US6337026B1 (en) | Leukocyte reduction filtration media | |
US5639376A (en) | Process for simultaneously removing leukocytes and methylene blue from plasma | |
US6159375A (en) | Method for removing leukocytes and methylene blue from plasma | |
JP4992120B2 (ja) | ウイルス及び白血球選択除去材およびその使用 | |
US7156240B2 (en) | Filter for processing blood and process for producing the same | |
JPH05148151A (ja) | 白血球除去用フイルター材料 | |
EP1507577A1 (en) | Leukocyte filter construction and a method of use thereof | |
JPWO2018034213A1 (ja) | 血液処理フィルター用フィルター要素、血液処理フィルター及び白血球除去方法 | |
JP3741320B2 (ja) | 白血球選択除去フィルター材 | |
KR20210035772A (ko) | 유기물 흡착용 담체 | |
JP3270125B2 (ja) | 白血球捕捉材 | |
JP7019054B2 (ja) | 血液処理フィルター及び血液処理フィルターの製造方法 | |
JP3657013B2 (ja) | 白血球除去フィルター材料、白血球除去装置および白血球除去方法 | |
JP2021137244A (ja) | 血液処理フィルター | |
JP2001347116A (ja) | 白血球除去フィルター装置 | |
JP2023081326A (ja) | 血液浄化用担体及び血液浄化カラム | |
JPH09122231A (ja) | 中空糸膜型白血球除去フィルター装置 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20070912 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20090915 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20090910 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20091214 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20100309 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20100405 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130409 Year of fee payment: 3 |
|
R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20140409 Year of fee payment: 4 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |