JP4212681B2 - Manufacturing method of plastic member - Google Patents
Manufacturing method of plastic member Download PDFInfo
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- JP4212681B2 JP4212681B2 JP14415898A JP14415898A JP4212681B2 JP 4212681 B2 JP4212681 B2 JP 4212681B2 JP 14415898 A JP14415898 A JP 14415898A JP 14415898 A JP14415898 A JP 14415898A JP 4212681 B2 JP4212681 B2 JP 4212681B2
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- Prior art keywords
- plastic
- plastic member
- liquid
- dispersion
- ptfe
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Description
【０００１】
【発明が属する技術分野】
本発明は、粒子状のプラスチック基材に分散液を添加してペースト化し、それを押し出し高温下で焼成することによりプラスチック部材を製造する製造方法に関し、特に、液体クロマトグラフを含む各種理化学・分析機器や製薬，半導体，液晶等を含む各種生産プロセス設備等において、液体（中）から溶存気体を除去するための脱気装置に使用するのに適したプラスチック部材の製造方法に関するものである。
【０００２】
【従来の技術】
例えば、液体クロマトグラフ装置においてサンプル液や溶媒，緩衝液等から溶存気体を除去する（脱気する）場合に脱気装置を用いるが、その脱気装置には上記サンプル液や溶媒，緩衝液等と接触する部分に、気体のみを通し液体の透過を阻止するフッ素系のプラスチック部材、具体的には、ポリテトラフルオロエチレン（ＰＴＦＥ）製などのチューブやフィルム・膜が使用される。
【０００３】
この種の脱気装置に使用されるポリテトラフルオロエチレン（ＰＴＦＥ）製のチューブやフィルム・膜は、通常、粉末状のポリテトラフルオロエチレンにガソリン留分（ナフサ，ホワイトオイル等）を添加混合させてペースト化し、それを押し出し高温（約１００℃〜４００℃）下で焼成することにより製造される。
その際、上記ガソリン留分などの低沸点液体は、焼成中に蒸発し除去されることになっている。しかし乍ら、実際には低沸点液体、、特に芳香族系物質及びオレフィン系物質は完全には蒸発せず、プラスチック部材に少量残留する。これらプラスチック部材中に残留した物質は、プラスチック部材に液体が接触した時に遊離して液体中に溶出し、液体クロマトグラフ装置などによる測定結果や各種生産プロセスでの品質維持管理に悪影響（測定誤差など）をもたらすことになる。
【０００４】
【発明が解決しようとする課題】
本発明は、この様な従来の不具合に鑑みてなされたものであり、液体クロマトグラフ装置等による測定結果や各種生産プロセスでの品質維持管理に悪影響をもたらす芳香族系物質及びオレフィン系物質が、プラスチック部材に接触した液体中に溶出する恐れがないプラスチック部材の製造方法を提供せんとするものである。
【０００５】
【課題を解決するための手段】
斯かる目的を達成する本発明のプラスチック部材の製造方法は、粒子状のプラスチック基材に分散液を添加混合してペースト化し、該ペースト化されたプラスチック基材を押し出し高温下で焼成することによりプラスチック部材を製造する方法において、前記分散液として揮発性が高く芳香族系物質及びオレフィン系物質を含まない単一溶液を用いることを特徴としたものである。
本発明の好ましい実施態様としては、前記分散液として、不飽和炭化水素を含まない直鎖状パラフィン系物質の揮発性が良く芳香族系物質及びオレフィン系物質を含まない単一溶液を用い、そして、前記プラスチック基材としてはポリテトラフルオロエチレン（ＰＴＦＥ）を用いる。
【０００６】
【実施の態様】
次に、本発明の好ましい実施態様について、詳細に説明する。
本発明に係るプラスチック部材は、粒子状のプラスチック基材に分散液を添加混合してペースト化し、ペースト化されたプラスチック基材を押出し機でチューブ状またはフィルム状または膜状に押し出し成形して、高温下で焼成することにより製造される。
尚、本明細書において、「粒子状」なる表現には、微粒子状態のものも含むものとする。
【０００７】
本発明に適用可能なプラスチック基材としては、気体のみを通し液体の透過を阻止するフッ素系のプラスチック基材、具体的には、ポリテトラフルオロエチレン（ＰＴＦＥ）やフッ素化エチレンプロピレン（ＦＥＰ），エチレンテトラフルオロエチレン（ＥＴＦＥ）等のフッ素を含む重合体を挙げることができるが、本発明はこれらの重合体に限定されるものではない。
【０００８】
また、粒子状プラスチック基材に添加混合する分散液としては、揮発性が高く芳香族系物質及びオレフィン系物質を含まない単一溶液を用いる。具体的には、不飽和炭化水素を含まない直鎖状パラフィン系物質等の揮発性が高く芳香族系物質及びオレフィン系物質を含まない単一溶液を分散液として用いる。
【０００９】
而して、プラスチック基材としてポリテトラフルオロエチレン（以下、ＰＴＦＥと略記する。）を用い、分散液として不飽和炭化水素を含まない直鎖状パラフィン系物質を用い、粒子状ＰＴＦＥに上記分散液を添加し混合して、ペースト状のＰＴＦＥを作成した。このペースト状ＰＴＦＥを押出し機でチューブ状に押し出し成形して焼成し、ＰＴＦＥ製のチューブを得た。
上記得られたＰＴＦＥ製チューブを、液体クロマトグラフ装置においてサンプル液や溶媒，緩衝液等から予め気体を除去する（脱気する）ための真空脱気装置に組込み、勾配溶離液体クロマトグラフ法により検出した。ちなみに、勾配溶離液体クロマトグラフ法では、クロマトグラフ操作中に移動相（溶媒）の濃度が連続的に変化し、移動相中に遊離した汚染物質は分離カラム内の勾配溶離中に濃縮されて、勾配中の対応する溶離剤の比率で溶出する。従って、例えば紫外線吸収のある芳香族系物質が検出器（紫外線吸収検出器）に入ると、測定に干渉する。
【００１０】
図１は、勾配溶離液体クロマトグラフ法で検出したクロマトグラムを示し、▲１▼は従来法により製造されたＰＴＦＥ製チューブを真空脱気装置に組込んだ液体クロマトグラフから得られたものであり、▲２▼は上記実施例の方法により製造されたＰＴＦＥ製チューブを真空脱気装置に組込んだ液体クロマトグラフから得られたものである。尚、検出には、アセトニトリル−水混合物を用い、検出器として波長２１０ｎｍの紫外線吸収検出器を使用した。
図１より明らかなとおり、従来法により製造されたＰＴＦＥ製チューブでは、液体クロマトグラフにおける測定結果に悪影響（誤り）をもたらす汚染が生じているのに対して、本発明の上記実施例１の方法により製造されたＰＴＦＥ製チューブでは、ほぼ平坦なベースラインを示し、サンプルの定量的測定に干渉がほとんど認められないことが理解される。
【００１１】
【発明の効果】
本発明に係るプラスチック部材の製造方法によれば、プラスチック基材をペースト化させる分散液として、揮発性が高く不飽和炭化水素を含まない直鎖状パラフィン系物質からなる単一溶液を用いるようにしたので、製造されたプラスチック部材に芳香族系物質及びオレフィン系物質が元より存在せず、従って、このプラスチック部材に液体が接触した時に芳香族系物質及びオレフィン系物質が遊離して液体中に溶出する恐れが全くなくなる。その結果、液体クロマトグラフ装置等による測定結果や各種生産プロセスでの品質維持管理に悪影響（測定誤差など）をもたらす恐れが全くなくなる。
【図面の簡単な説明】
【図１】 勾配溶離液体クロマトグラフ法で検出したクロマトグラムを示す。[0001]
[Technical field to which the invention belongs]
The present invention relates to a production method for producing a plastic member by adding a dispersion liquid to a particulate plastic base material, extruding it, and firing it at a high temperature, and in particular, various physics / analysis including a liquid chromatograph. The present invention relates to a method of manufacturing a plastic member suitable for use in a degassing device for removing dissolved gas from a liquid (medium) in various production process facilities including equipment, pharmaceuticals, semiconductors, and liquid crystals.
[0002]
[Prior art]
For example, when a dissolved gas is removed (degassed) from a sample solution, a solvent, a buffer solution, etc. in a liquid chromatograph device, a degasser is used. A fluorine-based plastic member that passes only gas and blocks liquid permeation, specifically, a tube, a film, or a film made of polytetrafluoroethylene (PTFE) or the like is used for a portion that contacts with the substrate.
[0003]
Tubes, films and membranes made of polytetrafluoroethylene (PTFE) used in this type of deaerator are usually made by adding a gasoline fraction (naphtha, white oil, etc.) to powdered polytetrafluoroethylene. It is made into a paste, extruded and fired at a high temperature (about 100 ° C. to 400 ° C.).
At that time, the low boiling point liquid such as the gasoline fraction is evaporated and removed during firing. However, in practice, low boiling point liquids, particularly aromatic materials and olefin materials, do not completely evaporate and remain in plastic parts in small amounts. Substances remaining in these plastic members are released when the liquid comes into contact with the plastic members and elutes into the liquid, adversely affecting the measurement results by the liquid chromatograph and the quality maintenance management in various production processes (measurement errors, etc.) ).
[0004]
[Problems to be solved by the invention]
The present invention has been made in view of such conventional problems, and aromatic substances and olefinic substances that have an adverse effect on measurement results by liquid chromatograph devices and the like and quality maintenance management in various production processes, It is an object of the present invention to provide a method for producing a plastic member that is not likely to elute into a liquid that contacts the plastic member.
[0005]
[Means for Solving the Problems]
The method for producing a plastic member of the present invention that achieves such an object includes adding a dispersion to a particulate plastic base material to form a paste, and extruding the pasted plastic base material and firing it at a high temperature. In the method for producing a plastic member, a single solution that is highly volatile and does not contain an aromatic substance and an olefinic substance is used as the dispersion.
As a preferred embodiment of the present invention, as the dispersion, a linear paraffinic material containing no unsaturated hydrocarbon is used, and a single solution containing no aromatic material and olefinic material is used. As the plastic substrate, polytetrafluoroethylene (PTFE) is used.
[0006]
Embodiment
Next, a preferred embodiment of the present invention will be described in detail.
The plastic member according to the present invention is made by adding and mixing a dispersion into a particulate plastic base material, and extruding the pasted plastic base material into a tube shape, a film shape, or a film shape with an extruder, Manufactured by firing at a high temperature.
In the present specification, the expression “particulate” includes those in a fine particle state.
[0007]
As a plastic base material applicable to the present invention, a fluorine-based plastic base material that passes only gas and blocks liquid permeation, specifically, polytetrafluoroethylene (PTFE), fluorinated ethylene propylene (FEP), Although polymers containing fluorine such as ethylenetetrafluoroethylene (ETFE) can be exemplified, the present invention is not limited to these polymers.
[0008]
Further, as the dispersion added to and mixed with the particulate plastic substrate, a single solution having high volatility and not containing an aromatic substance or an olefin substance is used. Specifically, a single solution that is highly volatile, such as a linear paraffinic material that does not contain unsaturated hydrocarbons, and that does not contain an aromatic or olefinic material is used as the dispersion.
[0009]
Thus, polytetrafluoroethylene (hereinafter abbreviated as PTFE) is used as the plastic substrate, and a linear paraffinic material not containing unsaturated hydrocarbon is used as the dispersion, and the above dispersion is added to the particulate PTFE. Were added and mixed to prepare a paste-like PTFE. This paste-like PTFE was extruded into a tube shape by an extruder and baked to obtain a PTFE tube.
The PTFE tube obtained above is installed in a vacuum degasser for removing gas from sample liquid, solvent, buffer, etc. in the liquid chromatograph in advance, and detected by gradient elution liquid chromatography. did. Incidentally, in gradient elution liquid chromatography, the concentration of the mobile phase (solvent) changes continuously during the chromatographic operation, and contaminants released in the mobile phase are concentrated during gradient elution in the separation column, Elute with the proportion of the corresponding eluent in the gradient. Therefore, for example, when an aromatic substance having ultraviolet absorption enters the detector (ultraviolet absorption detector), it interferes with the measurement.
[0010]
FIG. 1 shows a chromatogram detected by gradient elution liquid chromatography, and (1) is obtained from a liquid chromatograph in which a PTFE tube manufactured by a conventional method is incorporated in a vacuum degasser. And (2) are obtained from a liquid chromatograph in which a PTFE tube produced by the method of the above-described embodiment is incorporated in a vacuum deaerator. For detection, an acetonitrile-water mixture was used, and an ultraviolet absorption detector having a wavelength of 210 nm was used as a detector.
As is clear from FIG. 1, the PTFE tube manufactured by the conventional method is contaminated with an adverse effect (error) on the measurement result in the liquid chromatograph, whereas the method of the first embodiment of the present invention is used. It can be seen that the PTFE tube manufactured by, exhibits a substantially flat baseline and shows little interference in the quantitative measurement of the sample.
[0011]
【The invention's effect】
According to the manufacturing method for a plastic member according to the present invention, a plastic substrate as a dispersion to be pasted, to use a single solution comprised of a linear paraffinic materials that do not contain high unsaturated hydrocarbon volatile Therefore, the produced plastic member does not have aromatic substances and olefinic substances from the beginning. Therefore, when the liquid comes into contact with the plastic parts, the aromatic substances and olefinic substances are liberated into the liquid. There is no risk of elution. As a result, there is no possibility of adversely affecting the measurement results by the liquid chromatograph apparatus or the like and the quality maintenance management in various production processes (measurement error, etc.).
[Brief description of the drawings]
FIG. 1 shows a chromatogram detected by gradient elution liquid chromatography.
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14415898A JP4212681B2 (en) | 1998-05-26 | 1998-05-26 | Manufacturing method of plastic member |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14415898A JP4212681B2 (en) | 1998-05-26 | 1998-05-26 | Manufacturing method of plastic member |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11333900A JPH11333900A (en) | 1999-12-07 |
| JP4212681B2 true JP4212681B2 (en) | 2009-01-21 |
Family
ID=15355558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP14415898A Expired - Fee Related JP4212681B2 (en) | 1998-05-26 | 1998-05-26 | Manufacturing method of plastic member |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4212681B2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4504721B2 (en) * | 2004-04-07 | 2010-07-14 | オルガノ株式会社 | Liquid chromatography equipment |
-
1998
- 1998-05-26 JP JP14415898A patent/JP4212681B2/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| JPH11333900A (en) | 1999-12-07 |
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