JP4192029B2 - Injection syringe set - Google Patents

Injection syringe set Download PDF

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Publication number
JP4192029B2
JP4192029B2 JP2003122220A JP2003122220A JP4192029B2 JP 4192029 B2 JP4192029 B2 JP 4192029B2 JP 2003122220 A JP2003122220 A JP 2003122220A JP 2003122220 A JP2003122220 A JP 2003122220A JP 4192029 B2 JP4192029 B2 JP 4192029B2
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syringe
chamber
tip
container holder
solution
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JP2004321579A (en
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正弘 齋藤
充 星
昌彦 米谷
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Shimadzu Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2068—Venting means
    • A61J1/2075—Venting means for external venting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2031—Separating means having openings brought into alignment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2041—Separating means having removable plugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2065—Connecting means having aligning and guiding means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/008—Racks for supporting syringes or needles

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Description

【０００１】
【発明の属する技術分野】
本発明は、薬液をジェット噴射して皮下注射する噴射式の針無注射器と、前記針無注射器及び薬液を保持する容器ホルダーを一体管理可能な噴射式注射器セットに関し、特に全体長が短く、持ち運びの容易な噴射式注射器セットに関する。
【０００２】
【従来の技術】
従来の噴射式注射器セットは、図８に示すように、針無注射器１と、この針無注射器１と薬液バイアル３０を収容するキャップ状の容器ホルダー２（例えば、特許文献１参照。）からなり、前記容器ホルダー２には、薬液バイアル３０を収容する容器収容室１０と針無注射器１を嵌合保持する注射器嵌合室１１とが設けられていて、薬液バイアル３０が容器収容室１０に装填保持され、注射器嵌合室１１に注射器先端部７がねじ込まれて針無注射器１が容器ホルダー２と連結される構成を備えており、薬液バイアル３０は容器収容室１０で保護されて薬液バイアル３０の破損が確実に防止できる上、保管中は針無注射器１と容器ホルダー２が連結状態で一体管理され、この状態で薬液の吸入ができ、薬液バイアル３０と針無注射器本体が別々に保存されている場合に比べて、それぞれの蓋を外して取り扱う必要がなく、操作が簡単になる利点を備えている。
【０００３】
【特許文献１】
特開平１１−１８８０９５号公報
【０００４】
【発明が解決しようとする課題】
従来の噴射式注射器セットの容器ホルダーでは、薬液バイアルを針無注射器のノズルに向き合うように収納していたため、収納したときの全体長が長くなり持ち運びが不便であるという欠点があった。
【０００５】
本発明は、このような事情に鑑みて成されたものであり、針無注射器を収納したときの全長が短く、持ち運びの容易な噴射式注射器セットを提供することを目的とするものである。
【０００６】
【課題を解決するための手段】
上記の目的を達成するため、本発明の噴射式注射器セットは、薬液を噴射するジェット噴射口を注射器先端部の突端に備えた噴射式の針無注射器と、注射する薬液を入れてある薬液バイアルを装填保持する容器ホルダーとからなり、前記容器ホルダーには、隔壁をはさんで並設された、薬液バイアル全体を収容する容器収容室と、注射器先端部が嵌まり込む注射器嵌合室と、前記薬液バイアルの薬液を貯留しておく副室と、嵌合された針無注射器のジエット噴射口と副室に通じる細孔通路が形成されるとともに、前記薬液バイアルの薬液を前記副室に供給する中空針が設けられている。
【０００７】
また、本発明の噴射式注射器セットは、セット薬液を噴射するジェット噴射口を注射器先端部の突端に備えた噴射式の針無注射器と、注射する薬液を貯留しておく容器ホルダーとからなり、前記容器ホルダーには、前記注射器先端部が嵌まり込む注射器嵌合室と、隔壁をはさんで前記注射器嵌合室の上部に配設された薬液を貯留しておく薬液貯留室と、嵌合された針無注射器のジェット噴射口と前記薬液貯留室に通じる細孔通路が形成されている。
【００１０】
【発明の実施の形態】
以下、本発明の第一実施例を図面を参照しながら説明する。図１は第一実施例の噴射式注射器セットの針無注射器の先端部まわり及び容器ホルダーの縦断面図、図２は第一実施例に係わる針無注射器の外観を示す平面図である。
【００１１】
第一実施例の噴射式注射器セットは、図１および図２に示すように、薬液をジェット噴射する針無注射器１と、注射する薬液を入れてある薬液バイアル（薬液容器）３０を保持するキャップ状の容器ホルダー３とからなる。
【００１２】
前記針無注射器１は、図１に示すように、吸引された薬液が入る注射液室（シリンダ室）５の先端側がオリフィス６になっていて、注射器先端部７の突端に直径１５０μｍ程度のジェット噴射口８が開いている。一方、注射液室５の内部は、往復摺動できるようにしてピストン９が配設されており、薬液を吸引する時はピストン９が引き下げられ、逆に薬液を噴射する時はピストン９が急激に押し上げられる通常の針無注射器と同様の薬液噴射構造となっている。
【００１３】
ピストン９を引き下げる場合、図２に示す第１グリップＧＡを持って、第２グリップＧＢを回転操作し所望の吸引量を示す目盛りに合わせる。ピストン９を押し上げる場合は、注射器末端のリリースボタンＢＴを押す。リリースボタンＢＴが押されると内部の圧縮バネの圧力またはガスの圧力によってピストン９が急激に押し上げられて注射液室５の内の薬液がジェット噴射口８から勢いよくジェット噴射される。
【００１４】
前記容器ホルダー３には、薬液バイアル３０の全体が納められる内部形状を有する容器収容室１０と、注射器先端部７が嵌まり込める内部形状の注射器嵌合室１１とが隔壁１２をはさんで並設されるとともに、容器収容室１０と注射器嵌合室１１の上部に薬液を貯留しておく副室１３が形成されている。容器収容室１０の下端（開口１４）は、薬液バイアル３０の出入れのために、また、注射器嵌合室１１の下端（開口１５）は、注射器先端部７の出入れのために開口している。そして、容器収容室１０の開口１４には、取り外し可能な蓋１６が装着されている。この蓋１６は、その内周面に設けられたネジ山１６ａと開口１４の外周面に設けられたネジ山１４ａとからなるネジ結合構造によって取り外し可能に装着されている。注射器嵌合室１１の開口１５には、後述するように針無注射器１の先端部が装着されて閉塞される構造になっているので専用の蓋は必ずしも必要ではないが、専用の蓋で開口１５を閉塞できるようにしてもよい。容器ホルダー３の材質としては、アクリル樹脂やポリカーボネイト樹脂などの透明性のあるプラスチック製のものが、装填中の薬液バイアル３０の薬液残存量が外側から一目でわかるので好ましい。
【００１５】
前記副室１３の左方側の底部１３ａは、図１に示すように薬液が集まるように底部が小さくなっており、右方側の底部１３ｂより低くなるように形成され、底部１３ａより注射器嵌合室１１の先端面まで薬液流路１７が形成されるとともに、底部１３ｂより容器収容室１０の内部に先端を下方にして中空針１８が貫通している。
【００１６】
前記注射器嵌合室１１には、嵌まり込んだ注射器先端部７の突端をぴったり受け止める受当て面１９がゴム部材２１で形成されていて、ゴム部材２１の弾性により注射器先端部７の突端と受当て面１９が、すき間の無い状態でぴったり密接するようになっている。前記ゴム部材２１に形成された細孔２１ａを通して、針無注射器１のジェット噴射口８は、前記薬液流路１７と繋がっている。
【００１７】
この第一実施例の噴射式注射器セットでは、注射器先端部７が注射器嵌合室１１に嵌まり込んで、注射器先端部７の突端が受当て面１９に押し当てられるようにして分離可能に連結するネジ結合構造が、針無注射器１と容器ホルダー３の間に設けられている。すなわち、図１に示すように、注射器先端部７の外周面に設けられたネジ山７ａと、注射器嵌合室１１の開口１５側内周面に設けられたネジ山１５ａによるネジ結合構造が設けられていて、注射器先端部７を注射器嵌合室１１にネジ込めば、注射器先端部７が注射器嵌合室１１の奥に前進していき注射器先端部７の突端が受当て面１９に押し当てられた状態で針無注射器１と容器ホルダー３が連結し、逆にネジを緩めれば、注射器先端部７が注射器嵌合器１１から後退して来て針無注射器１と容器ホルダー３が分離される構成となっている。
【００１８】
次に第一実施例の噴射式注射器セットの使用形態について具体的に説明する。先ず図１に示すように、注射器嵌合室１１に針無注射器１を押し込んだ状態で、第１グリップＧＡを右方向に回転させ、さらにその回転が止まるところまで針無注射器を押し込む。これにより、針無注射器１の注射器先端部７は、容器ホルダー３の受当て面１９に密着した状態となる。
【００１９】
次いで、図３に示すように容器ホルダー３を、開口１４、１５が上側（副室１３が下側）となるよう上下を逆にし、容器収容室１０の蓋１６を取り外した後、薬液バイアル３０の口を塞いでいるゴム栓３１を中空針１８の先端１８ａに向けた状態で、薬液バイアル３０を容器収容室１０の中に中空針１８がゴム栓３１の中程まで刺し込まれるように押し込む。そして、蓋１６をネジ込みながら薬液バイアル３０をさらに押し込んでいく。蓋１６がネジ込めなくなると、蓋１６が取り付けられると同時に薬液バイアル３０が容器収容室１０にぴったりとガタ付かない状態で装填保持される。この状態では、薬液バイアル３０の全体が容器収容室１０内に納まっており、薬液バイアル３０が直接物に当たることがなく、中空針１８が曲がったりするなどの心配がない。
【００２０】
薬液バイアル３０を装填した状態を保持すると、最終的に、薬液バイアル３０内の薬液ＬＢは、徐々に副室１３内に徐々に流入するとともに、副室１３内の空気２５は圧縮されて副室１３の上方に集まる。そして、圧縮空気の圧力と副室１３内の薬液ＬＢに加わる荷重とがバランスする量の薬液ＬＢが副室１３内に貯留される。
【００２１】
次に、図１、図２を参照しながら皮下注射の実行について説明する。図３に示した状態の容器ホルダー３を図１に示す状態、すなわち、開口１４、１５が上側（副室１３が下側）となるよう上下を逆にし、針無注射器１の第２グリップＧＢを反時計方向に回して副室１３内の薬液ＬＢの必要量を吸引した後、針無注射器１の第１グリップＧＡを掴んで反対に回転してネジを緩め、針無注射器１を容器ホルダー３から分離する。そして、針無注射器１の注射器先端部７を注射箇所に当てておき、リリースボタンＢＴを押すと、ピストン９が押し上げられて薬液がジェット噴射口８から噴射されて患者の体に注入される。
【００２２】
次いで、第一実施例の噴射式注射器セットの保管の仕方を説明する。注射が済めば、針無注射器１の第１グリップＧＡを掴んで、図１に示すように、針無注射器１を注射器先端部７の突端が受当て面１９に押し当てられるまで注射器嵌合室１１に再びネジ込み、針無注射器１と容器ホルダー３を連結状態に戻す。後はそのままの状態で保管する。注射器先端部７の突端は受当て面１９に強く押し当てられているので、密閉状態が保たれ薬液バイアル３０から薬液ＬＢが漏れることはない。また、注射を行う都度、針無注射器１の注射器先端部７をアルコールの付いた脱脂綿で消毒することにより、受当て面１９も常は清潔な状態に保たれる。
【００２３】
上記のように、針無注射器１と容器ホルダー３が適切な状態で一体保管されとともに、全体長が短くなることにより携帯が容易となり、携帯される場合も常に針無注射器１と容器ホルダー３の一方を忘れること無く、両方が必ずセットで持ち運ばれることになり、糖尿病患者のようにインシュリンを日常的に打つ場合に特に好適であると言える。容器ホルダー３は繰り返し使用することができるが、薬液バイアル３０が空になった時、容器ホルダー３ごと廃棄するようにすると衛生的であり、取り扱いも楽である。
【００２４】
図４は、本発明の第二実施例による噴射式注射器セットの針無注射器の先端まわり及び容器ホルダーを示す縦断面図である。第二実施例の噴射式注射器セットは、薬液をジェット噴射する針無注射器１と、注射する薬液ＬＢを入れておくキャップ状の容器ホルダー４とから構成されている。
【００２５】
前記容器ホルダー４には、針無注射器１が嵌まり込む内部形状の注射器嵌合室１１と、その上部に薬液を貯留しておくための薬液貯留室２２と、この薬液貯留室２２内の薬液ＬＢを前記注射器嵌合室１１へ流入させるための薬液流路１７と、前記薬液貯留室２２に薬液ＬＢを供給するための薬液供給口２３及び密閉栓２４が設けられている。
【００２６】
次に、第二実施例の噴射式注射器セットの使用形態について説明する。針無注射器１に薬液を吸入するには、第１実施例の場合と同様に、容器ホルダー４の注射器嵌合室１１に針無注射器１を差し込み、第１グリップＧＡを回転してネジ込み固定する。そして、密閉栓２４を取り外した後、薬液バイアル３０の薬液を一旦通常の針付注射器に吸入した後、この針付注射器の注射針を薬液供給口２３に挿入して薬液ＬＢを注入し、密閉栓２４を取り付ける。そして、第２グリップＧＢを回転して所定の薬液量を吸入し、第１グリップＧＡを回して針無注射器１を容器ホルダー４から取り外して、患部に注射する。針無注射器１は容器ホルダー４に固定したままで保管される。前記密閉栓２４は、注射の度に取外しする必要はなく、薬液貯留室２２の薬液ＬＢが無くなったときに、取り外しすればよい。
【００２７】
図５は、本発明の第三実施例による噴射式注射器セットの針無注射器及び容器ホルダーを示す縦断面図である。第三実施例の噴射式注射器セットは、薬液をジェット噴射する針無注射器１と、薬液バイアル３０を収納したキャップ状の容器ホルダー３１がちょうつがい３２で折り畳めるように構成されている。
【００２８】
前記容器ホルダー３１には、薬液供給口３４を密封できるように容器用キャップ３３が設けられている。また、針無注射器１の先端には、注射器先端部７をカバーするノズル用キャップ３５が設けられている。
【００２９】
次に、第三実施例の噴射器セットの使用形態について説明する。針無注射器１に薬液を吸入するには、図６に示すように、容器用キャップ３３とノズル用キャップ３５を外し、容器ホルダー３１を注射器先端部７に接続し、固定する。そして、第２グリップＧＢを回転して所定の薬液量を吸入する。次に図７に示すように、容器用キャップ３３で薬液供給口３４にフタをし、容器ホルダー３１を折り曲げて針無注射器１の注射器先端部７を注射箇所に当てがい患部に注射する。注射後は、図５のようにそれぞれキャップをし、針無注射器１と容器ホルダー３１は折り畳んだ状態で保管される。
【００３０】
本発明の噴射式注射器セットは、上記実施例の形態にのみ限定されるものではなく、例えば、針無注射器１に縦溝、注射器嵌合室１１に縦突起物を設けて嵌合して結合したり、第２実施例の薬液供給口２３を無くし、針無注射器１を外して薬液流路１７側から薬液を注入するなどの変形実施が可能である。
【００３１】
【発明の効果】
以上述べたように、この発明の噴射式注射器セットによれば、針無注射器を収納したときの全長が短く、持ち運びの容易な噴射式注射器セットを提供することが可能となる。また、本実施例１、２においては、針無注射器と容器ホルダーの間に連結構造が設けられていて、針無注射器は、実際に皮下注射を実行する極く僅かな時間の他は、針無注射器と薬液容器とが連結状態にあって必ず一緒に存在し、本実施例３においても針無注射器および薬液容器を常に一体管理することが可能となり、操作性も向上する。また、本実施例１、２においては、保管時は常に薬液にノズル穴は浸されており、ノズル穴の目づまりを生じることも防げる。
【図面の簡単な説明】
【図１】第一実施例の噴射式注射器セットの縦断面図である。
【図２】第一実施例に係わる針無注射器の外観図である。
【図３】第一実施例の容器ホルダーへの薬液バイアルの装填状態を示す断面図である。
【図４】第二実施例の噴射式注射器セットの縦断面図である。
【図５】第三実施例の噴射式注射器セットの収納時の縦断面図である。
【図６】第三実施例の噴射式注射器セットの薬液取り込み時の縦断面図である。
【図７】第三実施例の噴射式注射器セットの注射時の縦断面図である。
【図８】従来の噴射式注射器セットの縦断面図である。
【符号の説明】
１ 針無注射器
３ 容器ホルダー
５ 注射液室
６ オリフィス
７ 注射器先端部
７ａ ネジ山
８ ジェット噴射口
９ ピストン
１０ 容器収容室
１１ 注射器嵌合室
１１ａ ネジ山
１２ 隔壁
１３ 副室
１３ａ、１３ｂ 底部
１４ 開口
１５ 開口
１５ａ ネジ山
１６ 蓋
１６ａ ネジ山
１７ 薬液流路
１８ 中空針
１９ 受当て面
２０ 隔壁
２１ ゴム部材
２１ａ 細孔
ＬＢ 薬液[0001]
BACKGROUND OF THE INVENTION
The present invention relates to an injection-type needleless syringe that jets a drug solution under a subcutaneous injection, and an injection-type syringe set that can integrally manage the needleless syringe and a container holder that holds the drug solution. The present invention relates to a simple injection type syringe set.
[0002]
[Prior art]
As shown in FIG. 8, the conventional injection syringe set includes a needleless syringe 1 and a cap-like container holder 2 (for example, refer to Patent Document 1) that houses the needleless syringe 1 and the drug solution vial 30. The container holder 2 is provided with a container housing chamber 10 for housing the medicinal solution vial 30 and a syringe fitting chamber 11 for fitting and holding the needleless syringe 1. The medicinal solution vial 30 is loaded into the container housing chamber 10. The syringe tip 7 is screwed into the syringe fitting chamber 11 and the needleless syringe 1 is connected to the container holder 2. The drug vial 30 is protected by the container storage chamber 10 and is stored in the drug vial 30. In addition, the needleless syringe 1 and the container holder 2 are integrally managed in a connected state during storage. In this state, the medicinal solution can be inhaled, and the medicinal solution vial 30 and the needleless syringe main body are separated. As compared with a case that is stored, it is not necessary to handle to remove the respective cover, and a benefit of operation is simplified.
[0003]
[Patent Document 1]
Japanese Patent Laid-Open No. 11-188095
[Problems to be solved by the invention]
In the container holder of the conventional injection type syringe set, since the drug solution vial is stored so as to face the nozzle of the needleless syringe, there is a disadvantage that the entire length when stored is inconvenient and the carrying is inconvenient.
[0005]
The present invention has been made in view of such circumstances, and an object of the present invention is to provide an injection type syringe set that has a short overall length when a needleless syringe is housed and is easy to carry.
[0006]
[Means for Solving the Problems]
In order to achieve the above object, an injection type syringe set according to the present invention includes an injection type needleless syringe provided with a jet injection port for injecting a chemical solution at the tip of the syringe tip, and a medical solution vial containing a medical solution to be injected. A container holder that holds the entire medicinal solution vial, and a syringe fitting chamber into which a syringe tip end fits, A sub-chamber for storing the medicinal solution in the medicinal solution vial, a jet injection port of the fitted needleless syringe, and a pore passage leading to the sub chamber are formed, and the medicinal solution in the medicinal solution vial is supplied to the sub chamber. A hollow needle is provided.
[0007]
Further, the injection type syringe set of the present invention comprises an injection type needleless syringe provided with a jet injection port for injecting a set drug solution at the tip of the syringe tip, and a container holder for storing the drug solution to be injected, The container holder is fitted with a syringe fitting chamber into which the tip of the syringe is fitted, a drug solution storage chamber for storing a drug solution disposed at the upper part of the syringe fitting chamber across a partition wall, and A fine hole passage is formed to communicate with the jet injection port of the needleless syringe and the drug solution storage chamber.
[0010]
DETAILED DESCRIPTION OF THE INVENTION
Hereinafter, a first embodiment of the present invention will be described with reference to the drawings. FIG. 1 is a longitudinal sectional view of the periphery of the tip of the needleless syringe and the container holder of the injection type syringe set of the first embodiment, and FIG. 2 is a plan view showing the appearance of the needleless syringe according to the first embodiment.
[0011]
As shown in FIG. 1 and FIG. 2, the injection type syringe set of the first embodiment is a needleless syringe 1 that jets a liquid medicine and a cap that holds a liquid vial (medical liquid container) 30 containing a liquid medicine to be injected. In the shape of a container holder 3.
[0012]
As shown in FIG. 1, the needleless syringe 1 has an orifice 6 at the tip side of an injection solution chamber (cylinder chamber) 5 into which a sucked drug solution enters, and a jet having a diameter of about 150 μm at the tip of the tip portion 7 of the syringe. The injection port 8 is open. On the other hand, a piston 9 is disposed in the injection solution chamber 5 so as to be able to slide back and forth. The piston 9 is pulled down when the chemical solution is sucked, whereas the piston 9 is suddenly ejected when the chemical solution is injected. It has the same chemical injection structure as a normal needleless syringe pushed up.
[0013]
When the piston 9 is pulled down, the first grip GA shown in FIG. 2 is held, and the second grip GB is rotated and adjusted to a scale indicating a desired suction amount. In order to push up the piston 9, the release button BT at the end of the syringe is pushed. When the release button BT is pressed, the piston 9 is suddenly pushed up by the pressure of the internal compression spring or the pressure of the gas, and the chemical liquid in the injection liquid chamber 5 is jetted vigorously from the jet injection port 8.
[0014]
In the container holder 3, a container housing chamber 10 having an internal shape in which the entire drug vial 30 can be accommodated and an internal shape syringe fitting chamber 11 in which the syringe tip 7 can be fitted are arranged across the partition wall 12. In addition, a sub chamber 13 is formed in the upper part of the container housing chamber 10 and the syringe fitting chamber 11 for storing a chemical solution. The lower end (opening 14) of the container housing chamber 10 is opened for taking in and out of the drug vial 30, and the lower end (opening 15) of the syringe fitting chamber 11 is opened for taking in and out of the syringe tip 7. Yes. A removable lid 16 is attached to the opening 14 of the container housing chamber 10. The lid 16 is detachably mounted by a screw coupling structure including a screw thread 16 a provided on the inner peripheral surface thereof and a screw thread 14 a provided on the outer peripheral surface of the opening 14. The opening 15 of the syringe fitting chamber 11 has a structure in which the distal end portion of the needleless syringe 1 is attached and closed as will be described later, so a dedicated lid is not necessarily required. 15 may be closed. The material of the container holder 3 is preferably made of a transparent plastic such as an acrylic resin or a polycarbonate resin because the remaining amount of the drug solution in the drug solution vial 30 being loaded can be seen at a glance from the outside.
[0015]
As shown in FIG. 1, the bottom portion 13a on the left side of the sub chamber 13 has a bottom portion that is small so that a chemical solution is collected, and is formed to be lower than the bottom portion 13b on the right side. A chemical liquid flow path 17 is formed up to the front end surface of the chamber 11, and a hollow needle 18 penetrates from the bottom portion 13 b into the container housing chamber 10 with the front end downward.
[0016]
In the syringe fitting chamber 11, a receiving surface 19 is formed by a rubber member 21 that exactly receives the protruding end of the inserted syringe tip 7. The elasticity of the rubber member 21 allows the receiving end 19 to receive the protruding end of the syringe tip 7. The abutment surface 19 is designed to be in close contact with no gap. The jet injection port 8 of the needleless syringe 1 is connected to the chemical liquid channel 17 through the pore 21 a formed in the rubber member 21.
[0017]
In the injection type syringe set of the first embodiment, the syringe tip 7 is fitted into the syringe fitting chamber 11 so that the protruding end of the syringe tip 7 is pressed against the receiving surface 19 so as to be separable. A screw coupling structure is provided between the needleless syringe 1 and the container holder 3. That is, as shown in FIG. 1, a screw coupling structure is provided by a screw thread 7 a provided on the outer peripheral surface of the syringe tip 7 and a screw thread 15 a provided on the inner peripheral surface of the opening 15 side of the syringe fitting chamber 11. If the syringe tip 7 is screwed into the syringe fitting chamber 11, the syringe tip 7 advances to the back of the syringe fitting chamber 11 and the tip of the syringe tip 7 is pressed against the receiving surface 19. If the needleless syringe 1 and the container holder 3 are connected to each other and the screw is loosened, the syringe tip 7 is retracted from the syringe fitting 11 and the needleless syringe 1 and the container holder 3 are separated. It becomes the composition which is done.
[0018]
Next, the usage form of the injection type syringe set of the first embodiment will be specifically described. First, as shown in FIG. 1, in a state where the needleless syringe 1 is pushed into the syringe fitting chamber 11, the first grip GA is rotated rightward, and the needleless syringe is pushed until the rotation stops. As a result, the syringe tip 7 of the needleless syringe 1 comes into close contact with the receiving surface 19 of the container holder 3.
[0019]
Next, as shown in FIG. 3, the container holder 3 is turned upside down so that the openings 14 and 15 are on the upper side (the sub chamber 13 is on the lower side), and the lid 16 of the container housing chamber 10 is removed. With the rubber plug 31 closing the mouth of the hollow needle 18 facing the tip 18a of the hollow needle 18, the drug vial 30 is pushed into the container housing chamber 10 so that the hollow needle 18 is inserted to the middle of the rubber plug 31. . Then, the chemical vial 30 is further pushed in while the lid 16 is screwed. When the lid 16 cannot be screwed in, the lid 16 is attached and at the same time, the medicinal solution vial 30 is loaded and held in a state in which the liquid container 30 does not loosely fit in the container housing chamber 10. In this state, the entire medicinal solution vial 30 is housed in the container housing chamber 10, so that the medicinal solution vial 30 does not directly hit an object, and there is no concern that the hollow needle 18 is bent.
[0020]
When the state in which the drug solution vial 30 is loaded is maintained, the drug solution LB in the drug solution vial 30 gradually flows into the sub chamber 13 gradually, and the air 25 in the sub chamber 13 is compressed and the sub chamber is compressed. Gather above 13. Then, an amount of the chemical liquid LB that balances the pressure of the compressed air and the load applied to the chemical liquid LB in the sub chamber 13 is stored in the sub chamber 13.
[0021]
Next, execution of subcutaneous injection will be described with reference to FIGS. The container holder 3 in the state shown in FIG. 3 is in the state shown in FIG. 1, that is, the second grip GB of the needleless syringe 1 is turned upside down so that the openings 14 and 15 are on the upper side (the sub chamber 13 is on the lower side). Is turned counterclockwise to suck the necessary amount of the liquid medicine LB in the subchamber 13 and then grasps the first grip GA of the needleless syringe 1 and rotates counterclockwise to loosen the screw. Separate from 3. When the syringe tip 7 of the needleless syringe 1 is placed on the injection site and the release button BT is pressed, the piston 9 is pushed up and the liquid medicine is injected from the jet injection port 8 and injected into the patient's body.
[0022]
Next, how to store the injection type syringe set of the first embodiment will be described. When the injection is completed, the first grip GA of the needleless syringe 1 is grasped, and the syringe fitting chamber is held until the protruding end of the syringe tip 7 is pressed against the receiving surface 19 as shown in FIG. Then, the needleless syringe 1 and the container holder 3 are returned to the connected state. After that, keep it as it is. Since the tip of the syringe tip 7 is strongly pressed against the receiving surface 19, the hermetically sealed state is maintained and the drug solution LB does not leak from the drug solution vial 30. Further, each time an injection is performed, the receiving surface 19 is normally kept clean by disinfecting the syringe tip 7 of the needleless syringe 1 with absorbent cotton with alcohol.
[0023]
As described above, the needleless syringe 1 and the container holder 3 are integrally stored in an appropriate state, and the entire length is shortened, so that the carrying becomes easy. Without forgetting one, both will always be carried in a set, and it can be said that it is particularly suitable when daily insulin is applied like a diabetic patient. Although the container holder 3 can be used repeatedly, it is hygienic and easy to handle if the container holder 3 is discarded when the chemical vial 30 becomes empty.
[0024]
FIG. 4 is a longitudinal sectional view showing the vicinity of the tip of the needleless syringe and the container holder of the injection type syringe set according to the second embodiment of the present invention. The injection type injector set of the second embodiment is composed of a needleless syringe 1 for jetting a drug solution and a cap-like container holder 4 for storing a drug solution LB to be injected.
[0025]
The container holder 4 has an internal syringe fitting chamber 11 into which the needleless syringe 1 is fitted, a chemical solution storage chamber 22 for storing a chemical solution in the upper portion thereof, and a chemical solution in the chemical solution storage chamber 22. A chemical liquid flow path 17 for allowing LB to flow into the syringe fitting chamber 11, a chemical liquid supply port 23 for supplying the chemical liquid LB to the chemical liquid storage chamber 22, and a sealing plug 24 are provided.
[0026]
Next, the usage form of the injection type syringe set of the second embodiment will be described. In order to inhale the drug solution into the needleless syringe 1, the needleless syringe 1 is inserted into the syringe fitting chamber 11 of the container holder 4 and the first grip GA is rotated and fixed in the same manner as in the first embodiment. To do. Then, after removing the sealing plug 24, the medicinal solution in the medicinal solution vial 30 is once sucked into a normal syringe with a needle, and then the injection needle of this syringe with a needle is inserted into the medicinal solution supply port 23 to inject the medicinal solution LB, A stopper 24 is attached. Then, the second grip GB is rotated to inhale a predetermined amount of drug solution, and the first grip GA is rotated to remove the needleless syringe 1 from the container holder 4 and inject it into the affected area. The needleless syringe 1 is stored while being fixed to the container holder 4. The sealing plug 24 does not need to be removed for each injection, and may be removed when the chemical solution LB in the chemical solution storage chamber 22 runs out.
[0027]
FIG. 5 is a longitudinal sectional view showing a needleless syringe and a container holder of an injection type syringe set according to a third embodiment of the present invention. The injection type syringe set of the third embodiment is configured such that a needleless syringe 1 for jetting a medical solution and a cap-like container holder 31 containing a medical solution vial 30 are folded by a hinge 32.
[0028]
The container holder 31 is provided with a container cap 33 so that the chemical solution supply port 34 can be sealed. In addition, a nozzle cap 35 that covers the syringe tip 7 is provided at the tip of the needleless syringe 1.
[0029]
Next, the usage pattern of the injector set of the third embodiment will be described. In order to inhale the drug solution into the needleless syringe 1, as shown in FIG. 6, the container cap 33 and the nozzle cap 35 are removed, and the container holder 31 is connected to the syringe tip 7 and fixed. Then, the second grip GB is rotated to inhale a predetermined chemical amount. Next, as shown in FIG. 7, the chemical solution supply port 34 is covered with the container cap 33, the container holder 31 is bent, and the syringe tip 7 of the needleless syringe 1 is applied to the injection site and injected into the affected area. After the injection, each cap is placed as shown in FIG. 5, and the needleless syringe 1 and the container holder 31 are stored in a folded state.
[0030]
The injection type syringe set of the present invention is not limited to the embodiment described above. For example, the needleless syringe 1 is provided with a vertical groove and the syringe fitting chamber 11 is provided with a vertical projection to be coupled and coupled. Alternatively, it is possible to perform modifications such as eliminating the chemical liquid supply port 23 of the second embodiment, removing the needleless syringe 1 and injecting the chemical liquid from the side of the chemical liquid flow path 17.
[0031]
【The invention's effect】
As described above, according to the injection type injector set of the present invention, it is possible to provide an injection type injection set that is easy to carry with a short overall length when the needleless syringe is accommodated. In the first and second embodiments, a connection structure is provided between the needleless syringe and the container holder, and the needleless syringe has a needle other than a very short time for actually performing subcutaneous injection. The syringeless device and the drug solution container are always in a connected state, and in the third embodiment, the needleless syringe and the drug solution container can always be managed integrally, and the operability is improved. In the first and second embodiments, the nozzle hole is always immersed in the chemical solution during storage, and clogging of the nozzle hole can be prevented.
[Brief description of the drawings]
FIG. 1 is a longitudinal sectional view of a jet injector set according to a first embodiment.
FIG. 2 is an external view of a needleless syringe according to the first embodiment.
FIG. 3 is a cross-sectional view showing a state in which a drug vial is loaded in the container holder of the first embodiment.
FIG. 4 is a longitudinal sectional view of a jet injector set according to a second embodiment.
FIG. 5 is a longitudinal sectional view of the injection type syringe set of the third embodiment when stored.
FIG. 6 is a longitudinal sectional view of the injection type syringe set according to the third embodiment when a chemical solution is taken in.
FIG. 7 is a longitudinal sectional view at the time of injection of the injection type syringe set of the third embodiment.
FIG. 8 is a longitudinal sectional view of a conventional injection syringe set.
[Explanation of symbols]
DESCRIPTION OF SYMBOLS 1 Needleless syringe 3 Container holder 5 Injection solution chamber 6 Orifice 7 Syringe tip 7a Thread 8 Jet injection port 9 Piston 10 Container accommodation chamber 11 Syringe fitting chamber 11a Thread 12 Partition 13 Sub chamber 13a, 13b Bottom 14 Open 15 Opening 15a Thread 16 Lid 16a Thread 17 Chemical liquid flow path 18 Hollow needle 19 Receiving surface 20 Bulkhead 21 Rubber member 21a Fine pore LB Chemical liquid

Claims (2)

薬液を噴射するジェット噴射口を注射器先端部の突端に備えた噴射式の針無注射器と、注射する薬液を入れてある薬液バイアルを装填保持する容器ホルダーとからなり、前記容器ホルダーには、隔壁をはさんで並設された、薬液バイアル全体を収容する容器収容室と、注射器先端部が嵌まり込む注射器嵌合室と、前記薬液バイアルの薬液を貯留しておく副室と、嵌合された針無注射器のジエット噴射口と副室に通じる細孔通路が形成されるとともに、前記薬液バイアルの薬液を前記副室に供給する中空針が設けられていることを特徴とする噴射式注射器セット。A jet type needleless syringe equipped with a jet injection port for injecting medicinal liquid at the tip of the syringe tip, and a container holder for loading and holding medicinal liquid vials containing medicinal liquid to be injected. A container housing chamber for holding the entire medicinal solution vial, a syringe fitting chamber into which the tip of the syringe fits, and a sub chamber for storing the medicinal solution in the medicinal vial are fitted together. A jet-type syringe set, characterized in that a fine needle passage leading to a jet injection port of a needleless syringe and a sub chamber is formed, and a hollow needle for supplying the drug solution in the drug vial to the sub chamber is provided. . 薬液を噴射するジェット噴射口を注射器先端部の突端に備えた噴射式の針無注射器と、注射する薬液を貯留しておく容器ホルダーとからなり、前記容器ホルダーには、前記注射器先端部が嵌まり込む注射器嵌合室と、隔壁をはさんで前記注射器嵌合室の上部に配設された薬液を貯留しておく薬液貯留室と、嵌合された針無注射器のジェット噴射口と前記薬液貯留室に通じる細孔通路が形成されていることを特徴とする噴射式注射器セット。A jet type needleless syringe equipped with a jet nozzle for ejecting a drug solution at the tip of the syringe tip and a container holder for storing the drug solution to be injected. The tip of the syringe is fitted in the container holder. A syringe fitting chamber to be trapped, a drug solution storage chamber for storing a drug solution disposed in the upper part of the syringe fitting chamber across a partition wall, a jet injection port of a needleless syringe fitted and the drug solution An injection type syringe set, wherein a pore passage leading to a storage chamber is formed.
JP2003122220A 2003-04-25 2003-04-25 Injection syringe set Expired - Lifetime JP4192029B2 (en)

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JP4192029B2 true JP4192029B2 (en) 2008-12-03

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7988660B2 (en) 2005-12-20 2011-08-02 Eli Lilly And Company Needle-free injection device
CN105050639B (en) 2013-03-15 2019-08-02 希普罗特克有限公司 Multi-chamber injection device

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