JP4126053B2 - Method for producing health food containing Kazuno Reishi - Google Patents
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- JP4126053B2 JP4126053B2 JP2005128014A JP2005128014A JP4126053B2 JP 4126053 B2 JP4126053 B2 JP 4126053B2 JP 2005128014 A JP2005128014 A JP 2005128014A JP 2005128014 A JP2005128014 A JP 2005128014A JP 4126053 B2 JP4126053 B2 JP 4126053B2
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Description
本発明は、鹿角霊芝を含有した健康食品の製造方法に関するものである。 The present invention relates to a manufacturing method of the health foods containing the Kazuno Reishi.
鹿角霊芝には、キチン質やβ−グルカン等の多糖類をはじめ、アデノシン、有機ゲルマニュウム、トリデルペン、ＬＰＳ、オリゴグルカンをはじめとする人体に有効な成分が多量に含まれ、これらの有効成分により抗癌，制癌，抗腫瘍，鎮痛，鎮静，抗酸性、免疫抵抗力向上、抗アレルギー等の種々の効果が得られることが知られている。 Kazuno Ganoderma contains a large amount of ingredients effective for the human body including polysaccharides such as chitin and β-glucan, adenosine, organic germanium, tridelpen, LPS, oligoglucan, etc. It is known that various effects such as anti-cancer, anti-cancer, anti-tumor, analgesia, sedation, acid resistance, immune resistance enhancement, anti-allergy and the like can be obtained.
特に鹿角霊芝には、免疫力を高めて秀れた抗癌効果，制癌効果を発揮し得るβ−グルカンが多量に含有されており、その量はアガリクスに含まれるβ−グルカンのおよそ３倍以上である。 In particular, Kazuno Ganoderma contains a large amount of β-glucan that enhances immunity and can exhibit excellent anticancer and anticancer effects, and the amount is about 3 of β-glucan contained in Agaricus. It is more than double.
ところで、この鹿角霊芝を服用する場合には、通常、鹿角霊芝を水に浸漬して有効成分をある程度抽出し、若しくは鹿角霊芝を煎じて有効成分をある程度抽出し、この抽出液を飲用している。 By the way, when you take this kakukaku reishi, you usually soak the kakukaku reishi and extract some of the active ingredients, or decoct the kakukaku reishi and extract some of the effective ingredients, and drink this extract is doing.
しかしながら、鹿角霊芝を単に水に浸漬したり煎じたりするだけでは、鹿角霊芝等のキノコ類の細胞膜は硬い為、細胞内若しくは細胞膜内に含有されている有効成分を効率良く多量に抽出することができず、よって、該鹿角霊芝中の有効成分を十分に抽出できているとは言い難い。 However, by simply immersing or decocting Kakuno Ganoderma in the water, the cell membrane of mushrooms such as Kakuno Ganoderma is stiff , so it can efficiently extract large amounts of active ingredients contained in cells or cell membranes. Therefore, it cannot be said that the active ingredient in the kakukaku reishi is sufficiently extracted.
また、前述の抽出液を服用しても、鹿角霊芝から抽出された前記有効成分は高分子状態となっている為、例えば腸管から体内に有効成分が効率良く吸収されているとは言い難い。 In addition, even if the above-mentioned extract is taken, the active ingredient extracted from Kakuno Ganoderma is in a polymer state, so it is difficult to say that the active ingredient is efficiently absorbed into the body from the intestinal tract, for example. .
従って、従来では、鹿角霊芝に含有される種々の有効成分による秀れた効能が十分に発揮されていないと言わざるを得ない。 Therefore, in the past, it must be said that the excellent effects of the various active ingredients contained in Kakuno Reishi are not fully exhibited.
本発明は、鹿角霊芝に含有される有効成分を該鹿角霊芝から非常に効率良く多量に抽出することが可能であり、その上、抽出された有効成分は体内に非常に吸収され易い状態とできる為、鹿角霊芝に含有される有効成分による種々の秀れた効能、即ち、例えば難治性疾患（ガン，アレルギー等）や生活習慣病（肝臓庇護，高血圧，糖尿病等）をはじめとする様々な疾病に対しての秀れた効果を十分に発揮し得る健康食品の製造方法を提供するものである。 The present invention is capable of extracting a large amount of effective components contained in Kakuno Ganoderma from the Kakuno Ganoderma very efficiently, and in addition, the extracted active components are very easily absorbed by the body. Therefore, various excellent effects of active ingredients contained in Kakuno Reishi, such as intractable diseases (cancer, allergies, etc.) and lifestyle-related diseases (liver protection, hypertension, diabetes, etc.) It is an object of the present invention to provide a method for producing a health food that can sufficiently exert excellent effects on various diseases.
本発明の要旨を説明する。 The gist of the present invention will be described.
鹿角霊芝から抽出した鹿角霊芝エキスに糖を加えて所定時間放置し、続いて、パパイヤを酵母菌及び乳酸菌により発酵して形成した発酵パパイヤ液と共に、更に鹿角霊芝を加えて水分が４０％〜６０％（重量）となるように発酵させることで第一発酵液を得、続いて、この第一発酵液に水分が４０％〜６０％（重量）となるようにブドウ糖及び澱粉を加えて発酵させることで第二発酵液を得、続いて、この第二発酵液を水分が７％〜８％（重量）となるように発酵乾燥させて第三発酵物を得、続いて、この第三発酵物を粉砕することを特徴とする鹿角霊芝を含有した健康食品の製造方法に係るものである。 Sugar is added to kakukaku reishi extract extracted from kakukaku reishi and left for a predetermined period of time . Subsequently, papaya is fermented with yeast and lactic acid bacteria and fermented papaya liquid is added, and kakukaku reishi is added to add moisture. % To 60% (weight) is obtained by fermentation to obtain the first fermented liquid, and then glucose and starch are added to the first fermented liquid so that the water content is 40% to 60% (weight). To obtain a second fermented liquid, and then fermented and dried the second fermented liquid so that the water content becomes 7% to 8% (by weight) to obtain a third fermented product. The present invention relates to a method for producing a health food containing deer anteater characterized by pulverizing a third fermented product .
また、請求項１記載の鹿角霊芝を含有した健康食品の製造方法において、前記鹿角霊芝エキスの抽出は、煮沸抽出であることを特徴とする鹿角霊芝を含有した健康食品の製造方法に係るものである。 The method for producing a health food containing deer antaceae according to claim 1, wherein the extraction of the deer anteater extract is boiled extraction. It is concerned.
また、請求項１，２いずれか１項に記載の鹿角霊芝を含有した健康食品の製造方法において、前記鹿角霊芝エキスに糖を加えて行う放置時間は、９〜１４時間であることを特徴とする鹿角霊芝を含有した健康食品の製造方法に係るものである。 Moreover, in the manufacturing method of the health food containing the kakukaku reishi in any one of Claims 1 and 2, the leaving time performed by adding sugar to the kakukaku reishi extract is that it is 9 to 14 hours. The present invention relates to a method for producing a health food containing the characteristic Kakuno Reishi.
また、請求項１〜３いずれか１項に記載の鹿角霊芝を含有した健康食品の製造方法において、前記第一発酵液を得る発酵は、４８〜７２日程度行うことを特徴とする鹿角霊芝を含有した健康食品の製造方法に係るものである。 Moreover, the manufacturing method of the health food containing the kakukaku reishi of any one of Claims 1-3 WHEREIN: Fermentation which obtains said 1st fermentation liquid is performed for about 48 to 72 days, The kakukaku spirit The present invention relates to a method for producing a health food containing turf.
また、請求項１〜４いずれか１項に記載の鹿角霊芝を含有した健康食品の製造方法において、前記第三発酵液を得る発酵乾燥は、風乾若しくは除湿乾燥で２５〜３５℃，６〜８日程度行うことを特徴とする鹿角霊芝を含有した健康食品の製造方法に係るものである。 Moreover, in the manufacturing method of the health food containing the kakukaku reishi in any one of Claims 1-4, fermentation drying which obtains said 3rd fermented liquid is 25-35 degreeC, 6 ~ The present invention relates to a method for producing a health food containing deer anteater which is performed for about 8 days .
本発明は上述のようにしたから、鹿角霊芝に含有される有効成分を該鹿角霊芝から非常に効率良く多量に抽出することが可能であり、その上、抽出された有効成分は体内に非常に吸収され易い状態となっている為、鹿角霊芝に含有される有効成分による種々の秀れた効能、即ち、例えば難治性疾患（ガン，アレルギー等）や生活習慣病（肝臓庇護，高血圧，糖尿病等）をはじめとする様々な疾病に対しての秀れた効果が効率的に発揮されることになる。 Since the present invention has been as described above, it is possible to very efficiently a large amount of extract the active ingredient contained in Kazuno Reishi from該鹿angle reishi, Moreover, effective component extracted in the body Because it is in a state that is very easily absorbed, various excellent effects of active ingredients contained in Kano ganshi, such as intractable diseases (cancer, allergies, etc.) and lifestyle-related diseases (liver protection, hypertension) Excellent effects on various diseases such as diabetes, etc.) can be efficiently exhibited.
鹿角霊芝を発酵させると、該鹿角霊芝の細胞膜が溶解され、該鹿角霊芝の細胞内若しくは細胞膜内に含有されている有効成分が外部に抽出される。 When fermenting deer Sumireishiba, dissolved cell membranes該鹿angle ganoderma, the active ingredient contained in the該鹿angle intracellular ganoderma or the cell membrane is extracted to the outside.
即ち、鹿角霊芝を単に水に含浸したり煎じたりする場合に比して、非常に多量の有効成を効率良く前記鹿角霊芝から抽出することができる。 In other words, a very large amount of effective composition can be efficiently extracted from the kakukaku reishi as compared with the case where the kakaku reishi is simply impregnated with water or decocted.
その上、鹿角霊芝の細胞内若しくは細胞膜内から抽出された有効成分は、前記発酵によって低分子化（非クラスタ化）され、これにより、該有効成分は服用することで例えば腸管から効率良く体内に吸収されることになる。 In addition, the active ingredient extracted from the cells or cell membranes of Kakuno Ganoderma is reduced in molecular weight (non-clustered) by the fermentation, whereby the active ingredient can be efficiently taken from the intestinal tract by taking the active ingredient. Will be absorbed.
これにより、鹿角霊芝から有効成分を効率良く多量に抽出することができ、更に該有効成分を体内に効率良く吸収できることで該有効成分による秀れた種々の効能が極めて良好に発揮される。 As a result, it is possible to efficiently extract a large amount of effective components from Kakuno Ganoderma and to absorb the effective components efficiently in the body, thereby exhibiting various excellent effects due to the effective components very well.
鹿角霊芝には、β−グルカン，アデノシン，有機ゲルマニウム，トリデルペンをはじめとする種々の秀れた有効成分が含有されている。例えばβ−グルカンは免疫力を高める作用を有し、アデノシンは血液をサラサラにする作用を有し、有機ゲルマニウムは鎮痛，鎮静作用を有し、トリデルペンは抗アレルギー作用を有する。従って、これらの有効成分によって難治性疾患（ガン，アレルギー等）や生活習慣病（肝臓庇護，高血圧，糖尿病等）に対する治癒力の向上、脳梗塞や脳溢血の発生の予防、鎮痛，鎮静効果、抗アレルギー効果をはじめとする秀れた効能が発揮される。 Kazuno Ganoderma contains various excellent active ingredients including β-glucan, adenosine, organic germanium, and tridelpen. For example, β-glucan has an action of enhancing immunity, adenosine has an action of making blood smooth, organogermanium has analgesic and sedative actions, and tridelpen has an antiallergic action. Therefore, these active ingredients improve the healing power for intractable diseases (cancer, allergies, etc.) and lifestyle-related diseases (liver protection, hypertension, diabetes, etc.), prevent the occurrence of cerebral infarction and cerebral hyperemia, analgesia, sedation, Excellent efficacy, including allergic effects.
しかも、鹿角霊芝の発酵を乳酸菌により行った場合には、該乳酸菌は、腸内において該腸内に存在する糖類を乳酸に分解する作用を発揮し、これにより、腸内を弱酸性に保って例えば病原菌や腐敗菌等の悪玉菌（ウェルシュ菌等）の増殖を抑えて善玉菌（ビフィズス菌等）が活発に活動できる状態となる為、一層効果的である。即ち、乳酸菌によって腸内に作り出された乳酸や酢酸等の有機酸により腸が刺激されて該腸のぜん動運動が活発となり、鹿角霊芝の有効成分が一層良好に消化吸収される状態が作出され、これにより、体内に吸収され易い低分子（非クラスタ化）状態の多量の鹿角霊芝の有効成分が、消化吸収の働きが非常に活発となった腸から極めて効率良く体内へ吸収され、上述の効果が一層良好に発揮される。 In addition, when the koji ganshiki is fermented with lactic acid bacteria, the lactic acid bacteria exert an action of decomposing sugars present in the intestine into lactic acid, thereby keeping the intestine weakly acidic. For example, it is more effective because good bacteria (such as bifidobacteria) can be actively activated while suppressing the growth of bad bacteria (such as Clostridium perfringens) such as pathogenic bacteria and spoilage bacteria. In other words, the intestine is stimulated by organic acids such as lactic acid and acetic acid produced in the intestine by lactic acid bacteria, and the intestinal peristaltic movement becomes active, and a state in which the active ingredient of deer antaceae is digested and absorbed better is created. As a result, a large amount of low-molecular-weight (non-clustered) active ingredients of deer antlerum that are easily absorbed by the body are absorbed into the body very efficiently from the intestine where the action of digestion and absorption has become very active. The effect of is exhibited more satisfactorily.
本発明の実施例を説明する。 Examples of the present invention will be described.
原料となる鹿角霊芝（例えば２０ｋｇ）を荒粉砕する。 Roshikaku Reishi (for example, 20 kg) as raw material is roughly crushed.
鹿角霊芝とは、薬用キノコである霊芝（マンネンタケ科マンネンタケ属）の変異体であり、鹿角の形状を有していることから「鹿角霊芝」と呼ばれている。 Kazuno Ganoderma is a variant of Ganoderma (Ganoderma genus), which is a medicinal mushroom, and is called “Kakuno Ganoderma” because it has the shape of Kano.
荒粉砕した鹿角霊芝の一部（例えば１８ｋｇ）に水（例えば３００リットル）を加えて煮沸抽出する。この煮沸抽出は、９５℃〜１００℃の状態で４５分間〜６０分間行う。 Some of the rough ground Kazuno Reishi (e.g. 18 kg) extract boiled water (for example, 300 liters). Boiling extraction This is performed 45 to 60 minutes in the state of 95 ° C. to 100 ° C..
煮沸抽出後、鹿角霊芝を濾過等により取り除き、鹿角霊芝エキス（例えば２００リットル）を得る。 After boiling extraction, the kakukaku reishi is removed by filtration or the like to obtain a kakukaku reishi extract (for example, 200 liters).
鹿角霊芝エキスに糖（例えば１３０ｋｇ）を加えて所定時間、例えば９時間〜１４時間放置する。 Kazuno Reishi extract a predetermined time by adding a sugar (e.g., 130 kg), the nine hours to 14 o'clock Maho location if example embodiment.
この糖としてはブドウ糖が採用されている。 Glucose is adopted as this sugar.
所定時間放置後、発酵パパイヤ液（例えば３６ｋｇ）を加える。 After leaving for a predetermined time, fermented papaya liquid (for example, 36 kg) is added.
発酵パパイヤ液とは、本発明者が既に取得済みの特許第３３７０３０２号（発明の名称：パパイヤを用いた健康食品の製造方法）により製造されるものが採用されている。 The fermented papaya liquid, the present inventors have already acquired the Japanese Patent No. 3370302: those prepared is adopted by (entitled health food production how using papaya).
この発酵パパイヤ液について説明すると、パパイヤをスライス若しくはミンチにより細分化し、続いて、糖類を加えて浸透圧によりパパイヤ細胞中のエキスをパパイヤ細胞外に抽出し、続いて、イースト菌やブドウ酒酵母菌等の酵母菌を加え毎日１回以上撹拌操作して該酵母菌及びパパイヤに元々付着している野生酵母菌を６乃至８日間発酵繁殖させ、続いて、乳酸菌を加えｐＨを３．５乃至４．０に保持しつつ１０乃至１５日間前記酵母菌，野生酵母菌及び乳酸菌を共生培養し、続いて、プレスにより液分を区分し、該液分に更にイースト菌やブドウ酒酵母菌等の酵母菌及び乳酸菌を加えつつ２０乃至６０日の発酵熟成を行うことで形成されるものを採用している。 Explaining this fermented papaya liquid, the papaya is subdivided into slices or mince, followed by adding sugars and extracting the extract in the papaya cells by osmotic pressure, followed by yeast, wine yeast, etc. The yeast and the wild yeast originally adhering to the papaya are fermented and propagated for 6 to 8 days, followed by the addition of lactic acid and the pH is adjusted to 3.5 to 4. The yeast, wild yeast and lactic acid bacterium are co-cultivated for 10 to 15 days while maintaining 0, and then the liquid is separated by pressing, and further yeast, such as yeast and wine yeast, and What is formed by performing fermentation ripening for 20 to 60 days while adding lactic acid bacteria is adopted.
具体的には、原料となるパパイヤとして国産品のパパイヤを採用する。輸入品の場合、パパイヤに多量の防腐剤や殺虫剤が使用されており、これら防腐剤や殺虫剤は健康食品を製造する上で好ましくない。また、無農薬品であることが望ましい。 Specifically, domestic papaya is adopted as the raw material. In the case of imported products, a large amount of preservatives and insecticides are used in papaya, and these preservatives and insecticides are not preferable for producing health foods. Moreover, it is desirable that it is an agrochemical-free product.
このパパイヤをスライス若しくはミンチにより細分化し、続いて、糖類を加えて浸透圧を変化せしめ、パパイヤ細胞中のエキスをパパイヤ細胞外に抽出する。 This papaya is subdivided by slicing or mincing, and then sugars are added to change the osmotic pressure, and the extract in the papaya cells is extracted out of the papaya cells.
尚、エキス中には、パパイン酵素及び多種多様の酵素（カタラーゼ，アミラーゼ，リパーゼ，プロテアーゼ，トレハラーゼ等），アミノ酸（必須アミノ酸各種），ビタミン（ビタミンＣ，ビタミンＥ，ベータカロチン等），ミネラル（必須ミネラル各種）その他栄養素（カテキン，フラボノイド，尿酸，金属結合タンパク質）が含まれる。 In addition, in the extract, papain enzyme and various enzymes (catalase, amylase, lipase, protease, trehalase, etc.), amino acids (various essential amino acids), vitamins (vitamin C, vitamin E, beta carotene, etc.), minerals (essential) Contains various minerals and other nutrients (catechins, flavonoids, uric acid, metal binding proteins).
また、パパイヤの細分化物と糖類とを少しづつ交互に加え、パパイヤ細胞に可及的に均一に浸透圧を加えるようにすると良い。 It is also preferable to add papaya subdivisions and sugars alternately little by little to apply osmotic pressure to papaya cells as uniformly as possible.
また、糖類としては、ブドウ糖を使用すると良い。ブドウ糖は、パパイヤの酸化を防止する作用を発揮し、しかも、カロリーが少なく、体内で直ぐにエネルギー源となる等の長所を有する。 Moreover, it is good to use glucose as saccharides. Glucose has an advantage of preventing the oxidation of papaya, and has fewer calories and immediately becomes an energy source in the body.
続いて、イースト菌やブドウ酒酵母菌等の酵母菌を加え毎日１回以上撹拌操作して該酵母菌及びパパイヤに元々付着している野生酵母菌を６乃至８日間発酵繁殖する。この発酵繁殖により、パパイヤに元々付着している野生酵母菌と加えられた前記酵母菌とがなじむ。 Subsequently, yeasts such as yeast and wine yeast are added and stirred once or more every day, and the wild yeasts originally attached to the yeasts and papayas are fermented and propagated for 6 to 8 days. By this fermentative reproduction, the wild yeast originally attached to the papaya and the added yeast are compatible.
続いて、乳酸菌を加えｐＨ３．５乃至４．０に保持しつつ１０乃至１５日間前記酵母菌，野生酵母菌及び乳酸菌を共生培養する。 Subsequently, the yeast, wild yeast and lactic acid bacteria are co-cultivated for 10 to 15 days while adding lactic acid bacteria and maintaining the pH at 3.5 to 4.0.
乳酸菌は乳酸を生成してｐＨを下げる性質を有するが、ｐＨを上記数値に保持する為、酸成分を可及的に生成しない乳酸菌を使用すると良い。 Lactic acid bacteria have the property of producing lactic acid and lowering the pH, but in order to maintain the pH at the above value, it is preferable to use a lactic acid bacterium that does not produce as much acid component as possible.
尚、共生培養を行う期間は、パパイヤ細胞中のエキスがパパイヤ細胞外に７０％程度抽出される時期（設備等により異なる為、予備実験しておくと良い。）とすると良い。 The period of co-cultivation is preferably a period when about 70% of the extract in the papaya cell is extracted outside the papaya cell (it may be preliminarily experimented because it varies depending on the equipment).
また、ここでいう酵母菌は、イースト菌，ブドウ酒酵母菌，アルコール酵母菌，ビール酵母菌等、一般的な酵母菌を示す。また、乳酸菌は、有胞子菌、例えばプランタルム,フェカリス,ビフィズス,ブルガリア及びサーモフィラスを採用している。 In addition, the yeast referred to here indicates general yeasts such as yeast, wine yeast, alcohol yeast, and brewer's yeast . Moreover, lactic acid bacteria, spore bacteria such plantarum, E. faecalis, Bifidobacterium employs Bulgaria and thermophilus.
続いて、プレスにより果肉分と液分とを区分する。 Subsequently, the pulp and liquid are separated by pressing.
続いて、液分を発酵タンクに移し、適時においてイースト菌やブドウ酒酵母菌等の酵母菌及び乳酸菌を加えつつ２０乃至６０日の発酵熟成を行い、ＳＯＤ（スーパーオキシドディスムターゼ）作用の強い液分として前記発酵パパイヤ液を形成する。 Subsequently, the liquid is transferred to a fermentation tank, and fermented and matured for 20 to 60 days while adding yeast and lactic acid bacteria such as yeast and wine yeast at an appropriate time, as a liquid with strong SOD (superoxide dismutase) action. Forming the fermented papaya liquor.
この発酵パパイヤ液は、体内摂取すると、腸内細菌のバランス、即ち、善玉細菌（代表的なものは乳酸菌）と悪玉細菌（代表的なものはウェルシュ菌）とのバランスを整える作用を有し、具体的な効果として確認されているものは、血液の浄化、細胞の活性化、血液循環の改善、動脈硬化の予防、消化吸収代謝の向上（即ち、栄養循環の向上）、病原菌，有害菌の増殖抑制及び感染抑制、免疫系の賦活、ホルモン，ビタミンの生産増大、有害物質，発ガン物質の分解及び***促進、腸内ｐＨの安定、腸活動の活発化、脂質代謝、糖代赭の改善、肝腎機能の活性化及び保全等が挙げられる。 When ingested in the body, this fermented papaya liquid has the action of adjusting the balance of enteric bacteria, that is, the balance between good bacteria (typically lactic acid bacteria) and bad bacteria (typically Clostridium perfringens), Specific effects that have been confirmed include blood purification, cell activation, improvement of blood circulation, prevention of arteriosclerosis, improvement of digestion and absorption metabolism (ie, improvement of nutrient circulation), pathogenic bacteria, harmful bacteria Suppression of growth and infection, activation of immune system, increased production of hormones and vitamins, decomposition of harmful substances and carcinogens, promotion of excretion, stabilization of intestinal pH, activation of intestinal activity, lipid metabolism, improvement of sugar substitutes, Examples include activation and maintenance of liver and kidney function.
鹿角霊芝にこの発酵パパイヤ液を加えた後、荒粉砕した鹿角霊芝の残り（例えば２ｋｇ）を混合して発酵させ第一発酵液を得る。 After adding this fermented papaya liquid to Kazuno Ganoderma, the remainder (for example, 2 kg) of coarsely ground Kano Kakureishi is mixed and fermented to obtain a first fermentation liquor.
この鹿角霊芝に発酵パパイヤ液を加えた後の発酵は、およそ４８日間〜７２日間行う。 Fermentation after adding the fermented papaya liquid to the kakukaku Reishi is performed for approximately 48 days to 72 days.
また、前記発酵は、第一発酵液の水分がおよそ４０％〜６０％（重量）となるように行われる。 Moreover, the said fermentation is performed so that the water | moisture content of a 1st fermentation liquid may be about 40%-60% (weight) .
第一発酵液にブドウ糖（例えば４ｋｇ）及び澱粉（例えば３０ｋｇ）を加えて第二発酵液を得る。 Glucose (for example, 4 kg) and starch (for example, 30 kg) are added to the first fermentation broth to obtain a second fermentation broth.
この第一発酵液へのブドウ糖及び澱粉の入れ込みは撹拌しながら行う。 The glucose and starch are introduced into the first fermentation broth while stirring.
このブドウ糖及び澱粉の入れ込みは、第二発酵液の水分がおよそ４０％〜６０％（重量）となるように行われる。 The glucose and starch are introduced so that the water content of the second fermentation broth is approximately 40% to 60% (weight) .
第二発酵液を発酵乾燥させて第三発酵物を得る。 The second fermented liquor is fermented and dried to obtain a third fermented product.
この発酵乾燥は、２５℃〜３５℃で風乾や除湿乾燥等によりおよそ６日間〜８日間行う。発酵乾燥を２５℃〜３５℃で風乾や除湿乾燥により行うのは、酵母菌や乳酸菌等の菌類が熱に弱いからである（乾燥温度が高いと、酵母菌や乳酸菌等の菌類が熱分解されてしまう。）。また、風乾する場合には、低風力で行う。 This fermentation and drying is performed at 25 ° C. to 35 ° C. by air drying or dehumidification drying for about 6 to 8 days. Fermentation drying is performed at 25 ° C. to 35 ° C. by air drying or dehumidification drying because fungi such as yeast and lactic acid bacteria are vulnerable to heat (if the drying temperature is high, fungi such as yeast and lactic acid bacteria are thermally decomposed. End up.) When air-drying, use low wind power.
第三発酵物を粉砕（荒粉砕，本粉砕）して製品化する。 The third fermented product is pulverized (rough pulverization, main pulverization) to produce a product.
尚、製品化された健康食品は、水分がおよそ７％〜８％の状態となる。 In addition, the commercialized health food has a water content of approximately 7% to 8%.
本実施例は上述のようにするから、鹿角霊芝に含有される有効成分を該鹿角霊芝から非常に効率良く多量に抽出することが可能であり、その上、抽出された有効成分は体内に非常に吸収され易い状態となっている為、鹿角霊芝に含有される有効成分による種々の秀れた効能、即ち、例えば難治性疾患（ガン，アレルギー等）や生活習慣病（肝臓庇護，高血圧，糖尿病等）をはじめとする様々な疾病に対して秀れた効果が良好に発揮される。 Since the present embodiment is as described above, it is possible to extract a large amount of the effective ingredient contained in Kakuno Ganoderma from the Kakuno Ganoderma very efficiently, and the extracted active ingredient is in the body. Since it is in a state that is very easily absorbed, various excellent effects due to the active ingredients contained in Kakuno Reishi, such as intractable diseases (cancer, allergies, etc.) and lifestyle-related diseases (liver protection, Excellent effect on various diseases including high blood pressure, diabetes, etc.).
即ち、鹿角霊芝エキスに含まれる有効成分は、酵母菌及び乳酸菌等の共生培養によって十分に発酵され、該発酵作用によって分子量６０００以下に低分子化（非クラスタ化）される為、該有効成分は服用することで例えば腸管等から非常に効率良く体内に吸収される。 In other words, the active ingredient contained in Kakuno Reishi extract is sufficiently fermented by symbiotic culture of yeast, lactic acid bacteria, etc., and is reduced to a molecular weight of 6000 or less (non-clustered) by the fermentation action. Can be absorbed into the body very efficiently, for example, from the intestinal tract.
しかも、鹿角霊芝を発酵させる発酵パパイヤ液は、腸内細菌のバランス、即ち、善玉細菌（代表的なものはビフィズス菌）と悪玉細菌（代表的なものはウェルシュ菌）とのバランスを整える作用を有し、該作用により消化吸収性が高まり、また、乳酸菌によって腸内に作り出された乳酸や酢酸等の有機酸により腸が刺激されて該腸のぜん動運動が活発となって、鹿角霊芝の有効成分が一層良好に消化吸収される状態が作出される。 Moreover, the fermented papaya liquid that ferments kakushi ganoderma mosquitoes balances the intestinal bacteria, that is, the balance between good bacteria (typically bifidobacteria) and bad bacteria (typically welsh bacteria). And the action increases the digestibility and absorption, and the intestine is stimulated by organic acids such as lactic acid and acetic acid produced in the intestine by lactic acid bacteria, and the peristaltic movement of the intestine is activated, A state in which the active ingredient is digested and absorbed better is created.
また、乳酸菌として、乾燥や強酸等厳しい環境下において生き延びる能力に秀れた有胞子菌を使用する。ことで、この有胞子菌は、胃酸や胆汁酸より死滅しにくい為、腸内まで確実に達し、前述したような、腸内細菌のバランスを整える効果がより確実且つ十分に発揮される。 In addition, as a lactic acid bacterium, a spore bacterium having an excellent ability to survive in a severe environment such as dryness or strong acid is used. Thus, since the spores are more difficult to kill than gastric acid and bile acids, the spores are surely reached into the intestine, and the effect of adjusting the balance of intestinal bacteria as described above is more reliably and sufficiently exhibited.
また、乳酸菌は、免疫細胞を活性化する効果を有するともいわれており、これにより、より一層抗酸化作用,抗腫瘍作用等の秀れた効能が発揮される。 In addition, lactic acid bacteria are also said to have an effect of activating immune cells, thereby exhibiting superior effects such as an antioxidant action and an antitumor action.
以上から、本実施例は、体内に吸収され易い低分子状態となった多量の鹿角霊芝の有効成分が、消化吸収の働きが非常に活発となった例えば腸から極めて効率良く体内へ吸収され、また、乳酸等の発酵によって産出される有効成分をも体内に吸収されることとなり、これにより、難治性疾患（ガン，アレルギー等）や生活習慣病（肝臓庇護，高血圧，糖尿病等）に対する治癒力の向上、脳梗塞や脳溢血の発生の予防、鎮痛，鎮静効果、抗アレルギー効果をはじめとする秀れた効能が得られる健康食品の製造方法となる。 From the above, in this example, a large amount of the active ingredient of deer antaceae in a low molecular weight state that is easily absorbed into the body is absorbed into the body very efficiently from the intestine, for example, where the action of digestion and absorption is very active. In addition, active ingredients produced by fermentation such as lactic acid will be absorbed into the body, which will cure intractable diseases (cancer, allergies, etc.) and lifestyle-related diseases (liver protection, hypertension, diabetes, etc.). improvement of force, prevention of the occurrence of cerebral infarction and cerebral hemorrhage, analgesic, sedative effect, Xiu the efficacy including antiallergic effect is the production method of the health food product obtained.
即ち、鹿角霊芝を単に水に浸漬したり煎じたりするだけでは、鹿角霊芝の細胞膜が硬い為、細胞内若しくは細胞膜内に含有されているキチン質やβ−グルカン等の多糖類をはじめ、アデノシン、有機ゲルマニュウム、トリデルペン、ＬＰＳ、オリゴグルカンをはじめとする有効成分を３７％程度しか抽出することができないが、本実施例においては、鹿角霊芝を発酵させることにより、該鹿角霊芝の細胞膜を溶解できるので、該鹿角霊芝の細胞内若しくは細胞膜内に含有されている有効成分のおよそ８０％以上を引き出すことができることを実験により確認している。 In other words, simply immersing or decocting Kakuno Ganoderma in the water, the cell membrane of Kakuno Ganoderma is stiff, so it contains chitin and polysaccharides such as β-glucan contained in the cell membrane, Although only about 37% of active ingredients such as adenosine, organic germanium, tridelpen, LPS, oligoglucan can be extracted, in this embodiment, the cell membrane of the deer anteater is fermented by fermentation. As a result, it has been confirmed by experiments that approximately 80% or more of the active ingredient contained in the cells or cell membranes of the deer antaceae can be extracted.
また、鹿角霊芝を単に水に浸漬したり煎じたりするだけでは、該鹿角霊芝から抽出された有効成分の２５％程度しか吸収できないが、本実施例においては、鹿角霊芝の細胞内若しくは細胞膜内から抽出された有効成分を前記発酵によって腸等から吸収できる程度に低分子化（非クラスタ化）させるため、鹿角霊芝から引き出した有効成分のおよそ９０％以上を体内に吸収できることも実験により確認している。 In addition, only about 25% of the active ingredient extracted from the Kakuno Ganoderma is absorbed by simply immersing or decocting the Kakuno Ganoderma in the present embodiment. Since the active ingredient extracted from the cell membrane is reduced to a low molecular weight (non-clustered) by the fermentation, it can be absorbed into the body by about 90% or more of the active ingredient drawn from Kakuno Reishi. It is confirmed by.
次に、本実施例の健康食品を服用することで得られる効能について説明する。 Next, the effects obtained by taking the health food of this example will be described.
本実施例の健康食品は、鹿角霊芝が免疫機能を強化する作用を有する為、癌になりにくい体質をつくる効能がある。 The health food of this example has the effect of making a constitution that is unlikely to cause cancer, because Kakuno Ganoderma has the effect of enhancing immune function.
また、本実施例の健康食品は、血液を改善する作用を有する為、水晶体への老廃物の沈着を防止して白内障を防ぐことができる。 Moreover, since the health food of a present Example has the effect | action which improves the blood, it can prevent the deposition of the waste material to a lens and can prevent a cataract.
また、本実施例の健康食品は、血流改善作用及び解毒作用を有する為、種々の肝障害を防ぐことができる。 Moreover, since the health food of a present Example has a blood-flow improvement effect and a detoxification effect, it can prevent various liver disorders.
また、本実施例の健康食品は、血流改善作用を有する為、膵臓を正常に働かせて血糖の上昇を防ぐことができる。 Moreover, since the health food of a present Example has a blood-flow improvement effect, it can work the pancreas normally and can prevent the raise of a blood glucose.
また、本実施例の健康食品は、血中ＬＤＬ（悪玉コレステロール）値を低下させ、ＨＤＬ（善玉コレステロール）を増加させる作用を有する為、高脂血症となることを防ぐことができる。 Moreover, since the health food of a present Example has the effect | action which reduces LDL (bad cholesterol) level in blood and increases HDL (good cholesterol), it can prevent becoming hyperlipidemia.
また、本実施例の健康食品は、血液改善作用を有する為、心臓の冠血管が詰まることを防止でき、これにより高血圧となることを防ぐことができる。 Moreover, since the health food of a present Example has a blood improvement effect | action, it can prevent that the coronary blood vessel of a heart is blocked and it can prevent becoming hypertension by this.
また、本実施例の健康食品は、血液改善作用を有する為、脳血管が詰まることを防止でき、これにより脳卒中や頭痛の発生を防ぐことができる。 Moreover, since the health food of the present embodiment has a blood improving action, it can prevent cerebrovascular clogging, thereby preventing the occurrence of stroke and headache.
また、本実施例の健康食品は、血液改善作用及びアミノ酸の補給作用を有する為、胃酸に負けない胃腸作りが行え、これにより胃腸潰瘍の発生を防ぐことができる。 In addition, since the health food of this example has a blood improving action and an amino acid replenishing action, it can produce a gastrointestine that is not inferior to gastric acid, thereby preventing the occurrence of gastrointestinal ulcers.
また、本実施例の健康食品は、血流改善作用を有する為、腸管を正常に働かせて下痢（水分吸収の低下）及び便秘（蠕動運動の低下）を防ぐことができる。 In addition, since the health food of this example has a blood flow improving action, the intestinal tract can be normally operated to prevent diarrhea (reduction in water absorption) and constipation (reduction in peristaltic movement).
本実施例の健康食品を被験者に１日５〜８ｇ程度、１０〜１４日間摂取してもらったところ、鹿角霊芝に含有される有効成分による種々の優れた効能、即ち、例えば難治性疾患（ガン，アレルギー等）や生活習慣病（肝臓庇護，高血圧，糖尿病等）をはじめとする様々な疾病に対して改善効果が得られることを確認した。 When the subject ingested the health food of this example for about 5 to 8 g per day for 10 to 14 days, various excellent effects due to the active ingredient contained in Kano ganshi, for example, intractable diseases ( It was confirmed that an improvement effect was obtained for various diseases including cancer, allergy, etc.) and lifestyle-related diseases (liver protection, hypertension, diabetes, etc.).
尚、本実施例では、鹿角霊芝エキスを発酵させて得られる発酵液を粉末化して製品化することとしたが、発酵液の状態で製品化しても良い。即ち、発酵液に発酵乾燥処理を施さず、若しくは、発酵液が乾燥固化しない程度まで発酵乾燥させることで得られる発酵液を製品化しても良い。 In this embodiment, the fermented liquor obtained by fermenting the kakukaku reishi extract is pulverized into a product. However, the fermented liquor may be commercialized in the state of the fermented solution. That is, you may commercialize the fermented liquor obtained by not fermenting and drying a fermented liquor, or fermenting and drying to such an extent that a fermented liquid does not dry and solidify.
また、本実施例では、鹿角霊芝エキスに発酵パパイヤ液を加えて発酵させることとしたが、鹿角霊芝に直接発酵パパイヤ液を加えて発酵させても良い。即ち、鹿角霊芝に酵母菌及び乳酸菌を含有した発酵パパイヤ液を加えて発酵させることで、該鹿角霊芝の細胞壁や細胞膜が破壊され、これにより、該細胞内や細胞膜内に含有されている有効成分をより一層多量に外部へ効率良く抽出することができる。 Further, in this embodiment, fermented papaya liquid is added to the kakukaku reishi extract and fermented. However, the fermented papaya liquid may be directly added to the kakukaku reishi and fermented. That is, by adding fermented papaya liquid containing yeast and lactic acid bacteria to Kakuno Ganoderma and fermenting it, the cell wall and cell membrane of Kano Ganoderma are destroyed, thereby being contained in the cell and cell membrane. A larger amount of the active ingredient can be efficiently extracted to the outside.
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