JP3300603B2 - Affected area measurement marker - Google Patents
Affected area measurement markerInfo
- Publication number
- JP3300603B2 JP3300603B2 JP16902096A JP16902096A JP3300603B2 JP 3300603 B2 JP3300603 B2 JP 3300603B2 JP 16902096 A JP16902096 A JP 16902096A JP 16902096 A JP16902096 A JP 16902096A JP 3300603 B2 JP3300603 B2 JP 3300603B2
- Authority
- JP
- Japan
- Prior art keywords
- mri
- contrast agent
- affected part
- marker
- state
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003550 marker Substances 0.000 title claims description 16
- 238000005259 measurement Methods 0.000 title description 2
- 239000002872 contrast media Substances 0.000 claims description 18
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 9
- 229910052799 carbon Inorganic materials 0.000 claims description 9
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 8
- 238000003325 tomography Methods 0.000 claims description 5
- 238000005481 NMR spectroscopy Methods 0.000 claims description 3
- 239000000696 magnetic material Substances 0.000 claims description 3
- 239000000499 gel Substances 0.000 description 6
- 238000003384 imaging method Methods 0.000 description 6
- 210000003625 skull Anatomy 0.000 description 6
- 239000002616 MRI contrast agent Substances 0.000 description 5
- LGMLJQFQKXPRGA-VPVMAENOSA-K gadopentetate dimeglumine Chemical compound [Gd+3].CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O LGMLJQFQKXPRGA-VPVMAENOSA-K 0.000 description 5
- 239000004918 carbon fiber reinforced polymer Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 229940044350 gadopentetate dimeglumine Drugs 0.000 description 3
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 230000001678 irradiating effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 240000008415 Lactuca sativa Species 0.000 description 1
- 229910021586 Nickel(II) chloride Inorganic materials 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 229910000365 copper sulfate Inorganic materials 0.000 description 1
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- QMMRZOWCJAIUJA-UHFFFAOYSA-L nickel dichloride Chemical compound Cl[Ni]Cl QMMRZOWCJAIUJA-UHFFFAOYSA-L 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 235000012045 salad Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Landscapes
- Magnetic Resonance Imaging Apparatus (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Description
【発明の詳細な説明】DETAILED DESCRIPTION OF THE INVENTION
【０００１】[0001]
【発明の属する技術分野】本発明は、定位脳手術を行う
際に、Ｘ線ＣＴまたは核磁気共鳴を利用したＭＲＩ（ma
gnetic resonance imaging）により頭部の断層撮影を行
って患部の位置を計測するために用いられる患部計測用
マーカに関する。BACKGROUND OF THE INVENTION The present invention relates to an MRI (matrix imaging) method utilizing X-ray CT or nuclear magnetic resonance when performing stereotactic brain surgery.
The present invention relates to a marker for measuring an affected part, which is used to measure the position of the affected part by performing tomography of the head by gnetic resonance imaging).
【０００２】[0002]
【発明が解決しようとする課題】定位脳手術を行う場
合、頭蓋固定装置により患者の頭部を固定し、Ｘ線ＣＴ
またはＭＲＩにより頭部の断層撮影を行って患部の位置
を計測することが行われている。この撮影の際に、頭蓋
固定装置に患部計測用のマーカを取り付け、撮影された
画像にそのマーカの基準棒が基準点として表示されるよ
うにし、その基準点に基づき、患部の位置を三次元的に
計測するようにしている。When performing stereotactic brain surgery, the patient's head is fixed by a cranial fixation device, and X-ray CT is performed.
Alternatively, tomography of the head is performed by MRI to measure the position of the affected part. At the time of this imaging, a marker for measuring the affected part is attached to the cranial fixation device so that the reference rod of the marker is displayed as a reference point in the captured image, and the position of the affected part is three-dimensionally determined based on the reference point. We are trying to measure it.
【０００３】この種のマーカの基準棒としては、Ｘ線Ｃ
Ｔの画像とＭＲＩの画像のどちらにも表示される必要が
あるため、例えば、カーボンＦＲＰ（カーボン繊維強化
プラスチック）製のパイプ内に、サラダ油などの液体状
のＭＲＩ用の造影剤を封入して構成されていた。この場
合、カーボンはＸ線ＣＴの画像に良好に表示され、ま
た、ＭＲＩ用の造影剤はＭＲＩの画像に良好に表示され
ることになる。[0003] As a reference rod of this type of marker, X-ray C
Since it is necessary to be displayed on both the T image and the MRI image, for example, a liquid MRI contrast agent such as salad oil is sealed in a pipe made of carbon FRP (carbon fiber reinforced plastic). Was composed. In this case, the carbon is favorably displayed on the X-ray CT image, and the contrast agent for MRI is favorably displayed on the MRI image.
【０００４】しかしながら、従来では、パイプ内に封入
されたＭＲＩ用の造影剤が液体状であるため、その造影
剤が漏れ出したり、或いは内部で気泡が発生したりする
ことがあった。造影剤が漏れ出した場合には、マーカと
して使用できなくなってしまうことになり、また、気泡
が発生した場合には、ＭＲＩの画像において基準点が不
明瞭となってしまうことになる。However, in the related art, since the MRI contrast agent sealed in the pipe is in a liquid state, the contrast agent may leak out or generate bubbles inside. If the contrast agent leaks out, it cannot be used as a marker, and if bubbles occur, the reference point will be unclear in the MRI image.
【０００５】本発明は上記した事情に鑑みてなされたも
のであり、その目的は、ＭＲＩ用の造影剤が漏れたり、
内部に気泡が発生したりすることを防止でき、Ｘ線ＣＴ
及びＭＲＩのどちらの撮影も常に良好に行うことができ
る患部計測用マーカを提供するにある。SUMMARY OF THE INVENTION The present invention has been made in view of the above circumstances, and has as its object to prevent leakage of a contrast agent for MRI,
The generation of air bubbles inside can be prevented and X-ray CT
An object of the present invention is to provide a marker for measuring a diseased part, which can always perform both radiographing and MRI.
【０００６】[0006]
【課題を解決するための手段】本発明は、上記の目的を
達成するために、頭蓋固定装置により患者の頭部を固定
し、Ｘ線ＣＴまたは核磁気共鳴を利用したＭＲＩにより
頭部の断層撮影を行って患部の位置を計測するために用
いられる患部計測用マーカにおいて、前記頭蓋固定装置
に取り付けられる台座と、この台座に取り付けられた複
数本の基準棒とを備え、前記基準棒を、カーボンを主体
とする外パイプと、この外パイプ内に挿入された非磁性
体製のパイプ状の容器と、この容器の内部にゲル状に硬
化させた状態で密封状態に充填されたＭＲＩ用の造影剤
とにより構成したことを特徴とするものである。SUMMARY OF THE INVENTION In order to achieve the above-mentioned object, the present invention provides a method of fixing a patient's head by a cranial fixation device, and performing X-ray CT or MRI using nuclear magnetic resonance. In the affected part measurement marker used to measure the position of the affected part by performing imaging, a pedestal attached to the skull fixing device, comprising a plurality of reference rods attached to the pedestal, the reference rod, An outer pipe mainly composed of carbon, a non-magnetic pipe-shaped container inserted into the outer pipe, and an MRI filled in a hermetically sealed state in a state of being cured in a gel state inside the container. And a contrast agent.
【０００７】上記した手段によれば、ＭＲＩ用の造影剤
としては、液体状ではなく、ゲル状に硬化した状態とな
っているので、外部へ漏れ難く、また、内部に気泡が発
生することもない。しかも、ＭＲＩ用の造影剤を外パイ
プとは別の容器に密封しているので、その造影剤の品質
を一層安定した状態に保持することができる。According to the above-mentioned means, the contrast agent for MRI is not in a liquid state but in a cured state in a gel state, so that it hardly leaks to the outside and bubbles are generated inside. Absent. Moreover, since the MRI contrast agent is sealed in a container other than the outer pipe, the quality of the contrast agent can be maintained in a more stable state.
【０００８】[0008]
【発明の実施の形態】以下、本発明の一実施例について
図面を参照して説明する。まず、図４及び図５におい
て、患者の頭部Ａを固定する頭蓋固定装置１は、固定枠
２と、この固定枠２に取り付けられた４本の固定ピン３
とを備えていて、固定枠２に頭部Ａを挿入した状態で、
その頭部Ａを４本の固定ピン３により固定する構成とな
っている。そして、固定枠２において、これの左右両側
部及び上下部の４箇所に、本発明に係わる患部計測用の
マーカ４が着脱可能に取り付けられるようになってい
る。図４及び図５においては、マーカ４が固定枠２の左
右両側部と上部の３箇所に取り付けられた状態が示され
ている。DESCRIPTION OF THE PREFERRED EMBODIMENTS One embodiment of the present invention will be described below with reference to the drawings. First, in FIGS. 4 and 5, a skull fixing device 1 for fixing a patient's head A includes a fixing frame 2 and four fixing pins 3 attached to the fixing frame 2.
With the head A inserted into the fixed frame 2,
The head A is fixed by four fixing pins 3. In the fixed frame 2, markers 4 for measuring a diseased part according to the present invention are detachably attached to four positions on the left and right sides and the upper and lower portions. FIGS. 4 and 5 show a state where the markers 4 are attached to the left and right sides and the upper portion of the fixed frame 2.
【０００９】各マーカ４は、図２に示すように、ねじ５
により上記固定枠２に取付固定される台座６と、この台
座６と平行に配置された連結板７と、これら台座６と連
結板７との間に配設された５本の基準棒８，９，１０，
１１，１２とから構成されている。５本の基準棒８〜１
２のうち、両側に位置する２本の基準棒８，１２と中央
部に位置する基準棒１０とは平行に配置されている。残
る２本の基準棒９と１１は、連結板７を底辺とすると共
に頭蓋固定装置１の原点Ｏを頂点とする、二等辺三角形
を形成するように配置されている。As shown in FIG. 2, each marker 4 has a screw 5
Pedestal 6 attached to and fixed to the fixed frame 2, a connecting plate 7 arranged in parallel with the pedestal 6, five reference rods 8 disposed between the pedestal 6 and the connecting plate 7, 9,10,
11 and 12. 5 reference rods 8-1
2, two reference rods 8, 12 located on both sides and a reference rod 10 located at the center are arranged in parallel. The remaining two reference bars 9 and 11 are arranged so as to form an isosceles triangle having the connecting plate 7 as the base and the vertex at the origin O of the skull fixing device 1.
【００１０】各基準棒８〜１２は同一の構成であり、具
体的には図１に示すような構成となっている（図１には
基準棒８を代表として示す）。すなわち、外側に位置す
る外パイプ１３と、この外パイプ１３内に挿入されたパ
イプ状の容器１４と、この容器１４の内部に密封状態に
充填されたＭＲＩ用の造影剤１５とから構成されてい
る。Each of the reference rods 8 to 12 has the same configuration, and specifically has a configuration as shown in FIG. 1 (the reference rod 8 is shown as a representative in FIG. 1). That is, it is composed of an outer pipe 13 located on the outside, a pipe-shaped container 14 inserted into the outer pipe 13, and a contrast agent 15 for MRI filled inside the container 14 in a sealed state. I have.
【００１１】このうち、外パイプ１３は、Ｘ線ＣＴの画
像に良好に表示されるカーボンを主体とした材料、この
場合カーボンＦＲＰ（カーボン繊維強化プラスチック）
によって形成されている。また、容器１４の材質として
は、Ｘ線ＣＴ及びＭＲＩの画像に悪影響を与えず、しか
も水分を通しにくい非磁性材料として、この場合フッ素
樹脂、或いはポリエチレンによって形成されている。そ
して、ＭＲＩ用の造影剤１５としては、例えば、ガドペ
ンテト酸ジメグルミン（マグネビスト（商品名））を用
い、これを工業用寒天であるアクリルアミドと混合して
ゲル状に硬化させた状態で、上記容器１４の内部に密封
状態に充填している。この場合、ガドペンテト酸ジメグ
ルミンとアクリルアミドの混合比（重量比）は、ガドペ
ンテト酸ジメグルミンを１としたときに、アクリルアミ
ドを５００〜１０００とすることが好ましい。Of these, the outer pipe 13 is made of a material mainly composed of carbon which is well displayed on an X-ray CT image, in this case, carbon FRP (carbon fiber reinforced plastic).
Is formed by The container 14 is made of a non-magnetic material that does not adversely affect X-ray CT and MRI images and does not easily pass moisture, and in this case, is made of fluororesin or polyethylene. As the contrast agent 15 for MRI, for example, gadopentetate dimeglumine (Magnevist (trade name)) is used, mixed with acrylamide, which is industrial agar, and cured in a gel state. Is filled in a sealed state. In this case, it is preferable that the mixing ratio (weight ratio) of gadopentetate dimeglumine and acrylamide be 500 to 1000 when dimeglumine gadopentetate is 1.
【００１２】しかして、図４及び図５に示すように、患
者の頭部Ａを頭蓋固定装置１により固定すると共に、頭
蓋固定装置１に患部計測用のマーカ４を取り付けた状態
で、例えばＭＲＩにより頭部Ａの断層撮影を行うと、図
３に示すように、その画像１６には、病変部位である患
部Ｂと共に、各マーカ４の基準棒８〜１２が基準点８ａ
〜１２ａとして表示される。この場合、各基準棒８〜１
０のうちＭＲＩ用の造影剤１５部分が基準点８ａ〜１２
ａとして点で表示される。As shown in FIGS. 4 and 5, the patient's head A is fixed by the skull fixing device 1 and the skull fixing device 1 is attached with the marker 4 for measuring an affected part, for example, MRI. When the tomography of the head A is performed as shown in FIG. 3, the reference rods 8 to 12 of the markers 4 are displayed on the image 16 together with the diseased part B which is a lesion site, as shown in FIG.
~ 12a. In this case, each reference rod 8 to 1
0, the contrast agent 15 for MRI is the reference point 8a to 12
It is displayed as a point.
【００１３】そして、この画像１６において、マーカ４
の中心軸Ｌ１，Ｌ２から患部Ｂまでの寸法ｘ，ｙを計測
し、この寸法ｘ，ｙと、画像１６の縮尺度に基づき、実
際の患部の、固定枠２の原点ＯからＸ方向及びＹ方向の
距離を計測できる。また、画像１６において、マーカ４
の二等辺三角形の斜辺を構成する２本の基準棒９，１１
に対応する基準点９ａ，１１ａ間の寸法ｚを計測し、こ
の寸法ｚと、画像１６の縮尺度に基づき、実際の患部
の、固定枠２の原点ＯからＺ方向の距離を計測できる。
これらにより、実際の患部の位置を、固定枠２の三次元
の座標で表すことができる。そして、このようして求め
た患部の位置に対して、治療器、例えば吸引針を導入し
たり、或いはライナック等のＸ線照射装置によりＸ線を
照射することにより、治療を行うことができる。In the image 16, the marker 4
Are measured from the central axes L1 and L2 of the affected part B to the affected part B, and based on the dimensions x and y and the reduced scale of the image 16, the X direction and the Y from the origin O of the fixed frame 2 of the actual affected part are measured. The distance in the direction can be measured. In the image 16, the marker 4
Two reference rods 9 and 11 forming the hypotenuse of the isosceles triangle
Is measured between the reference points 9a and 11a, and the distance of the actual affected part in the Z direction from the origin O of the fixed frame 2 can be measured based on this dimension z and the reduced scale of the image 16.
Thus, the actual position of the affected part can be represented by the three-dimensional coordinates of the fixed frame 2. Then, the treatment can be performed by introducing a therapeutic device, for example, a suction needle, or irradiating X-rays with an X-ray irradiating device such as a linac to the position of the affected part thus obtained.
【００１４】Ｘ線ＣＴにより頭部Ａの断層撮影を行う場
合も、上記したＭＲＩの場合と同様に行うことができ
る。なお、このＸ線ＣＴの画像では、図示はしないが、
各基準棒８〜１０のうち、カーボンを主体とした外パイ
プ１３の部分が基準点として小さなリング状で表示され
る。The tomography of the head A by X-ray CT can be performed in the same manner as in the above-mentioned MRI. Although not shown in this X-ray CT image,
Of the reference rods 8 to 10, the portion of the outer pipe 13 mainly composed of carbon is displayed in a small ring shape as a reference point.
【００１５】上記した実施例によれば、マーカ４の各基
準棒８〜１２を、カーボンを主体とした外パイプ１３
と、この外パイプ１３内に挿入された非磁性体製の容器
１４と、この容器１４の内部に充填されたＭＲＩ用の造
影剤１５とにより構成したことにより、Ｘ線ＣＴ及びＭ
ＲＩのどちらの撮影も良好に行うことができる。また、
ＭＲＩ用の造影剤１５としては、液体状ではなく、ゲル
状に硬化した状態となっているので、外部へ漏れ難く、
また、内部に気泡が発生することもない。しかも、ＭＲ
Ｉ用の造影剤１５を外パイプ１３とは別の容器１４に密
封しているので、その造影剤１５の品質を一層安定した
状態に保持することができる。従って、ＭＲＩ用の造影
剤１５が漏れたり、内部に気泡が発生したりすることを
防止でき、Ｘ線ＣＴ及びＭＲＩのどちらの撮影も常に良
好に行うことができる。According to the above-described embodiment, the reference rods 8 to 12 of the marker 4 are connected to the outer pipe 13 mainly made of carbon.
And a container 14 made of a non-magnetic material inserted into the outer pipe 13 and a contrast agent 15 for MRI filled in the container 14, so that the X-ray CT and M
Both RI imaging can be performed favorably. Also,
As the contrast agent 15 for MRI, it is hardly leaked to the outside because it is not in a liquid state but in a hardened state in a gel state.
Also, no bubbles are generated inside. And MR
Since the contrast agent 15 for I is sealed in a container 14 different from the outer pipe 13, the quality of the contrast agent 15 can be maintained in a more stable state. Therefore, it is possible to prevent the contrast agent 15 for MRI from leaking or to generate air bubbles inside, and it is possible to always favorably perform both X-ray CT and MRI imaging.
【００１６】本発明は、上記した実施例にのみ限定され
るものではなく、次のように変形または拡張することが
できる。ＭＲＩ用の造影剤１５としては、ガドペンテト
酸ジメグルミンに代えて、生理食塩水（ＮａＣｌ）に塩
化ニッケルを少量混ぜた溶液、或いは、硫酸銅水溶液を
用い、これをゲル状に硬化させるようにしてもよい。The present invention is not limited to the above embodiment, but can be modified or expanded as follows. As the contrast agent 15 for MRI, instead of gadopentetate dimeglumine, a solution obtained by mixing a small amount of nickel chloride in physiological saline (NaCl) or an aqueous solution of copper sulfate is used, and this is cured into a gel. Good.
【００１７】[0017]
【発明の効果】以上の説明にて明らかなように、本発明
によれば、基準棒を、カーボンを主体とした外パイプ
と、この外パイプ内に挿入された非磁性体製の容器と、
この容器の内部にゲル状に硬化させた状態で密封状態に
充填されたＭＲＩ用の造影剤とにより構成したことによ
り、ＭＲＩ用の造影剤が漏れたり、内部に気泡が発生し
たりすることを防止でき、Ｘ線ＣＴ及びＭＲＩのどちら
の撮影も常に良好に行うことができるという優れた効果
を奏する。As apparent from the above description, according to the present invention, the reference rod is made of an outer pipe mainly composed of carbon, a non-magnetic container inserted into the outer pipe,
The container is made up of an MRI contrast agent that is filled in a sealed state in a state of being cured in a gel state, thereby preventing the MRI contrast agent from leaking or generating bubbles inside. This provides an excellent effect that both X-ray CT and MRI can always be performed well.
【図１】要部の拡大破断正面図FIG. 1 is an enlarged cutaway front view of a main part.
【図２】マーカの斜視図FIG. 2 is a perspective view of a marker.
【図３】ＭＲＩによる画像を示す図FIG. 3 is a diagram showing an image obtained by MRI.
【図４】使用状態を示す側面図FIG. 4 is a side view showing a use state.
【図５】同状態の正面図FIG. 5 is a front view of the same state.
１は頭蓋固定装置、４はマーカ、６は台座、８〜１２は
基準棒、８ａ〜１２ａは基準点、１３は外パイプ、１４
は容器、１５は造影剤、Ａは頭部、Ｂは患部である。1 is a skull fixing device, 4 is a marker, 6 is a pedestal, 8 to 12 are reference bars, 8a to 12a are reference points, 13 is an outer pipe, 14
Is a container, 15 is a contrast agent, A is a head, and B is an affected part.
フロントページの続き (56)参考文献 特開 平５−111472（ＪＰ，Ａ) 特開 平３−60642（ＪＰ，Ａ) 特開 平１−299533（ＪＰ，Ａ) 特開 昭61−73308（ＪＰ，Ａ) 特開 昭61−73306（ＪＰ，Ａ) 特開 昭61−73305（ＪＰ，Ａ)Continuation of the front page (56) References JP-A-5-111472 (JP, A) JP-A-3-60642 (JP, A) JP-A-1-299533 (JP, A) JP-A-61-73308 (JP) JP-A-61-73306 (JP, A) JP-A-61-73305 (JP, A)
Claims (1)
し、Ｘ線ＣＴまたは核磁気共鳴を利用したＭＲＩにより
頭部の断層撮影を行って患部の位置を計測するために用
いられるものであって、 前記頭蓋固定装置に取り付けられる台座と、この台座に
取り付けられた複数本の基準棒とを備え、 前記基準棒を、 カーボンを主体とする外パイプと、 この外パイプ内に挿入された非磁性体製のパイプ状の容
器と、 この容器の内部にゲル状に硬化させた状態で密封状態に
充填されたＭＲＩ用の造影剤とにより構成したことを特
徴とする患部計測用マーカ。An apparatus for fixing a patient's head by a cranial fixing device and performing tomography of the head by X-ray CT or MRI using nuclear magnetic resonance to measure the position of an affected part. A pedestal attached to the skull-fixing device, and a plurality of reference rods attached to the pedestal, wherein the reference rod is an outer pipe mainly composed of carbon; A marker for measuring an affected part, comprising: a pipe-shaped container made of a magnetic material; and a contrast agent for MRI, which is filled in a sealed state in a state of being gel-cured inside the container.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16902096A JP3300603B2 (en) | 1996-06-28 | 1996-06-28 | Affected area measurement marker |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16902096A JP3300603B2 (en) | 1996-06-28 | 1996-06-28 | Affected area measurement marker |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH1014909A JPH1014909A (en) | 1998-01-20 |
| JP3300603B2 true JP3300603B2 (en) | 2002-07-08 |
Family
ID=15878848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16902096A Expired - Fee Related JP3300603B2 (en) | 1996-06-28 | 1996-06-28 | Affected area measurement marker |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3300603B2 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009006935A1 (en) * | 2007-07-06 | 2009-01-15 | Karolinska Institutet Innovations Ab | Stereotactic surgery system |
| US11253727B2 (en) | 2017-10-18 | 2022-02-22 | Sunnybrook Research Institute | Magnetic resonance visible markers for magnetic resonance imaging guided brachytherapy |
| GB2572220A (en) * | 2018-03-23 | 2019-09-25 | Elekta ltd | Markers for radiotherapy apparatus |
| KR102323957B1 (en) * | 2019-07-26 | 2021-11-08 | 경북대학교 산학협력단 | Imaging markers for all magnetic resonance imaging and computed tomography and Manufacturing Method Thereof |
-
1996
- 1996-06-28 JP JP16902096A patent/JP3300603B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH1014909A (en) | 1998-01-20 |
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