JP3184114B2 - Moisturizer - Google Patents
MoisturizerInfo
- Publication number
- JP3184114B2 JP3184114B2 JP09233797A JP9233797A JP3184114B2 JP 3184114 B2 JP3184114 B2 JP 3184114B2 JP 09233797 A JP09233797 A JP 09233797A JP 9233797 A JP9233797 A JP 9233797A JP 3184114 B2 JP3184114 B2 JP 3184114B2
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- JP
- Japan
- Prior art keywords
- soymilk
- soybean
- present
- fermentation
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Description
【０００１】[0001]
【発明の属する技術分野】本発明は、大豆抽出液にビフ
ィドバクテリウム属の微生物を作用せしめて得られる発
酵生成物を有効成分とし、皮膚角質層の水分保持能に優
れた保湿剤及びこれを含有する使用感の優れた化粧料に
関する。TECHNICAL FIELD The present invention relates to a moisturizer having a fermentation product obtained by allowing a microorganism of the genus Bifidobacterium to act on a soybean extract as an active ingredient, and having an excellent water-retaining ability for the stratum corneum of the skin and a moisturizer. The present invention relates to a cosmetic composition having excellent feeling in use.
【０００２】[0002]
【従来の技術】従来、大豆抽出液、特に豆乳を用いた化
粧料は数多く報告されており、保湿効果、洗浄効果があ
るとされている（特開昭６２−３６３０４号公報等）。
しかしながら、これらの化粧料は、化粧料の性質として
最も重要な保湿効果が十分ではなかった。一方、豆乳に
リゾープス属の微生物を作用させたもの（特開平１−１
０２０１１号公報）及び乳酸菌を作用させたもの（特開
平３−１２７７１３号公報）を化粧料に用いることが報
告されている。しかしながら、これら発酵生成物は、保
湿効果を有するものは見出されておらず、更に大豆臭や
発酵臭もあり、化粧料に用いるのは問題であった。2. Description of the Related Art Conventionally, many cosmetics using soybean extract, especially soymilk, have been reported, and are considered to have a moisturizing effect and a washing effect (Japanese Patent Application Laid-Open No. Sho 62-36304).
However, these cosmetics did not have sufficient moisturizing effect, which is the most important property of cosmetics. On the other hand, soymilk treated with a microorganism of the genus Rhizopus (Japanese Unexamined Patent Publication No.
No. 020111) and those treated with lactic acid bacteria (Japanese Patent Application Laid-Open No. 3-127713) have been reported to be used in cosmetics. However, these fermentation products have not been found to have a moisturizing effect, and also have a soybean odor and a fermentation odor, and have been problematic for use in cosmetics.
【０００３】[0003]
【発明が解決しようとする課題】従って本発明の目的
は、大豆抽出液を原料としながらも臭気が少なく、保湿
効果の高い保湿剤及びこれを含有する化粧料を提供する
ことにある。SUMMARY OF THE INVENTION Accordingly, an object of the present invention is to provide a humectant having a low odor and a high moisturizing effect using a soybean extract as a raw material, and a cosmetic containing the same.
【０００４】斯かる実状において本発明者らは上記課題
を解決すべく鋭意研究を行った結果、豆乳にビフィドバ
クテリウム属の微生物を作用させて得られる発酵生成物
が、臭気が少なく、保湿効果が高く、かつ化粧料に用い
た場合の使用感に優れていることを見出し本発明を完成
した。Under such circumstances, the present inventors have conducted intensive studies to solve the above-mentioned problems. As a result, the fermentation product obtained by allowing a microorganism of the genus Bifidobacterium to act on soymilk has a low odor and a moisturizing effect. The present invention was found to be highly effective and excellent in the feeling of use when used in cosmetics, and completed the present invention.
【０００５】すなわち本発明は、ビフィドバクテリウム
属から選ばれる１種又は２種以上の微生物を豆乳に作用
させて得られる発酵生成物を有効成分とする保湿剤を提
供するものである。[0005] That is, the present invention provides a humectant containing, as an active ingredient, a fermentation product obtained by allowing one or more microorganisms selected from the genus Bifidobacterium to act on soymilk.
【０００６】[0006]
【０００７】[0007]
【発明の実施の形態】豆乳から本発明の保湿剤を製造す
る工程の一例を次に挙げる。BEST MODE FOR CARRYING OUT THE INVENTION An example of a process for producing the humectant of the present invention from soymilk is described below.
【０００８】（１）豆乳の製造（工程１） 本発明で用いる豆乳はいかなる方法で製造されたもので
あってもよいが、例えば、原料となる大豆を水につけた
後、熱水又は０．５〜１．０重量％の炭酸ナトリウムを
含む熱水を添加して磨砕後、おからを取り除き、更に加
熱殺菌することにより製造することができる。通常、固
型分濃度１０重量％程度のものを用いる。(1) Production of soymilk (Step 1) The soymilk used in the present invention may be produced by any method. It can be manufactured by adding hot water containing 5 to 1.0% by weight of sodium carbonate, grinding, removing okara, and sterilizing by heating. Usually, a solid component concentration of about 10% by weight is used.
【０００９】ここで、本発明において用いられる豆乳の
原料となる大豆は、特に制限はないが、油脂を含有した
丸大豆、脱皮大豆、又はフレーク大豆等を原料としたも
のが好ましく、特に脱皮大豆を原料としたものが好まし
い。Here, the soybean used as the raw material for soymilk used in the present invention is not particularly limited, but preferably is a soybean-containing soybean, such as whole soybean, dehulled soybean, or flaked soybean. Is preferred.
【００１０】また、かかる豆乳には、必要に応じて、製
造後、次の工程である微生物処理のために、ショ糖、ブ
ドウ糖、果糖、転化糖等の食品に用いられる糖や、肉エ
キス、ペプトン、酵母エキス、ペプチド等の微生物の増
殖に必要な栄養素を添加してもよく、微生物の至適pHに
調整するために豆乳にクエン酸、リンゴ酸、アスコルビ
ン酸、乳酸、酢酸等の食品に用いられる酸を添加しても
よい。[0010] If necessary, the soymilk may be added to sugars used in foods such as sucrose, glucose, fructose, invert sugar, meat extract, etc. for the next step of microbial treatment after production. Nutrients necessary for the growth of microorganisms such as peptone, yeast extract, and peptide may be added.To adjust the pH of microorganisms to the optimal pH, soy milk is added to foods such as citric acid, malic acid, ascorbic acid, lactic acid, and acetic acid. The acid used may be added.
【００１１】（２）大豆の発酵（工程２） 前記工程１で製造した豆乳に微生物を作用させる方法は
特に限定されず、例えば、培養した微生物の菌液を上記
豆乳に接種した後、その微生物に適した温度、時間、条
件を適宜決定して発酵を行えばよい。なお、発酵は、菌
株を複数種組み合わせた混合発酵であってもよいし、菌
株を複数種組み合わせた連続発酵であってもよい。(2) Fermentation of soybean (step 2) The method of causing a microorganism to act on the soymilk produced in the above step 1 is not particularly limited. The fermentation may be performed by appropriately determining the temperature, time, and conditions suitable for the fermentation. The fermentation may be a mixed fermentation in which a plurality of strains are combined, or a continuous fermentation in which a plurality of strains are combined.
【００１２】大豆抽出液に作用させるビフィドバクテリ
ウム属に属する微生物としては、特に限定されず、例え
ば、ビフィドバクテリウム ビフィダム、ビフィドバク
テリウム ロンガム、ビフィドバクテリウム アドレッ
センティス、ビフィドバクテリウム インファンティ
ス、ビフィドバクテリウム ブレーベ等が挙げられ、こ
れらは１種でも２種以上を混合して用いてもよい。ま
た、これら微生物と共にラクトバチルス ストレプトコ
ッカス、ラクトコッカス等の乳酸菌を発酵させ、これら
の発酵生成物を利用してもよい。The microorganisms belonging to the genus Bifidobacterium which act on the soybean extract are not particularly limited, and include, for example, Bifidobacterium bifidum, Bifidobacterium longum, Bifidobacterium adressentis, Bifidobacterium Uminfantis, Bifidobacterium breve and the like, and these may be used alone or in combination of two or more. In addition, lactic acid bacteria such as Lactobacillus streptococcus and Lactococcus may be fermented together with these microorganisms, and their fermentation products may be used.
【００１３】得られた発酵生成物は、そのまま保湿剤と
して用いることができるが、エタノールを添加し、遠心
分離することにより高分子物質を除去してから用いるこ
とがより好ましい。使用する場合は更に濃縮又は希釈し
て固型分濃度で１〜３０重量％、好ましくは２〜２５重
量％に調製して用いるとよい。The obtained fermentation product can be used as it is as a humectant. However, it is more preferable to use ethanol after adding ethanol and removing high molecular substances by centrifugation. When it is used, it may be further concentrated or diluted to a solid content concentration of 1 to 30% by weight, preferably 2 to 25% by weight.
【００１４】本発明の化粧料は、上記保湿剤を含有する
ものであり、その含有量は、０．０１〜１００重量％と
することが好ましく、特に０．１〜９０重量％とするこ
とが好ましい。The cosmetic of the present invention contains the above-mentioned humectant, and its content is preferably 0.01 to 100% by weight, particularly 0.1 to 90% by weight. preferable.
【００１５】本発明の化粧料は、更にヒアルロン酸、グ
リセリン、豆乳に乳酸菌を接種して得られた培養液、乳
成分の乳酸菌培養液等の保湿成分を配合することにより
更に保湿効果を高めることができる。これら保湿成分の
うちヒアルロン酸が特に好ましい。The cosmetic of the present invention further enhances the moisturizing effect by blending a moisturizing component such as a culture solution obtained by inoculating lactic acid bacteria into hyaluronic acid, glycerin, and soy milk, and a lactic acid bacteria culture solution of milk components. Can be. Of these moisturizing components, hyaluronic acid is particularly preferred.
【００１６】また、本発明の化粧料には、本発明の効果
を妨げない範囲で公知の化粧料成分、例えば、水、アル
コール類、油成分、界面活性剤、防腐剤、香料、色素等
を配合することができる。The cosmetic of the present invention contains known cosmetic components such as water, alcohols, oil components, surfactants, preservatives, fragrances, pigments and the like within a range not to impair the effects of the present invention. Can be blended.
【００１７】本発明の化粧料は、常法により製造するこ
とができ、化粧水、乳液、保湿クリーム、クレンジング
クリーム、マッサージクリーム、洗顔クリーム、パッ
ク、美容液等種々の形態とすることができる。The cosmetic of the present invention can be produced by a conventional method, and can be in various forms such as lotion, milky lotion, moisturizing cream, cleansing cream, massage cream, face wash cream, pack, and serum.
【００１８】[0018]
【発明の効果】本発明の保湿剤は、皮膚角質層の水分保
持能に優れるものである。また、このものは大豆臭がほ
とんど消失しており、発酵臭も少ない。更に、保湿剤に
よく見られるべたつき感も少なく、これを配合すれば優
れた保湿作用と良好な使用感を有する化粧料が得られ
る。The humectant of the present invention is excellent in the ability of the stratum corneum to retain moisture. In addition, the soybean odor has almost disappeared, and the fermentation odor is also small. Furthermore, the sticky feeling often seen in the humectant is small, and if it is blended, a cosmetic having an excellent moisturizing action and a good feeling of use can be obtained.
【００１９】[0019]
【実施例】次に実施例を挙げて本発明を詳細に説明する
が、本発明はこれらに限定されるものではない。Next, the present invention will be described in detail with reference to examples, but the present invention is not limited to these examples.
【００２０】製造例１ 大豆を水洗し、水に一夜浸漬して十分に吸水させ４倍量
の水を加えミキサーでペースト状に粉砕した。これを１
００℃で３０分間加熱して冷却後、濾過して豆乳を得た
（固型分濃度約１０重量％）。得られた豆乳を１００
℃、９０分間蒸気滅菌して発酵用素豆乳を調製した。前
培養した上記微生物のビフィドバクテリウム ブレーベ
ＹＩＴ ４０６５の菌液をこれに接種した後、３７
℃、２４時間静置培養して発酵大豆を得た。Production Example 1 Soybeans were washed with water, immersed in water overnight, sufficiently absorbed, added with 4 times the amount of water, and ground into a paste with a mixer. This one
The mixture was heated at 00 ° C. for 30 minutes, cooled, and then filtered to obtain soymilk (solid content: about 10% by weight). 100 of the resulting soy milk
The mixture was steam sterilized at 90 ° C. for 90 minutes to prepare raw soybean milk for fermentation. After inoculating the precultured bacterial solution of the above microorganism, Bifidobacterium breve YIT 4065, 37
The fermented soybean was obtained by culturing at 24 ° C. for 24 hours.
【００２１】試験例１ 上記製造例で得られた発酵豆乳１００mlにエタノール３
００mlを添加して十分混和した後、遠心分離によって生
じた沈殿を除去した。これを減圧乾固して５０％エタノ
ールを１０ml添加した（固型分濃度２３重量％）。ま
た、同様の操作を発酵前の素豆乳についても行った。温
度２４℃、湿度４５％の環境を維持した測定室におい
て、女性パネラー１０名の前腕内側皮膚にサンプルを１
０μｌ／cm2 （２．３mg／cm2 ）塗布し、皮膚角質層の
水分含有量の経時変化をコンダクタンスメータ（ＩＢＳ
社製 ＳＫＩＣＯＮ−２００）にて測定した。コンダク
タンスは５回測定した平均値を求め、更に、１０名の平
均値で表した。得られた結果を表１に示す。Test Example 1 Ethanol 3 was added to 100 ml of the fermented soymilk obtained in the above-mentioned production example.
After adding 00 ml and mixing well, the precipitate generated by centrifugation was removed. This was evaporated to dryness under reduced pressure, and 10 ml of 50% ethanol was added (solid content concentration: 23% by weight). In addition, the same operation was performed on raw soybean milk before fermentation. In a measurement room maintained at an environment of a temperature of 24 ° C. and a humidity of 45%, a sample was placed on the skin inside the forearm of 10 female panelists.
0 μl / cm 2 (2.3 mg / cm 2 ), and the change over time in the water content of the stratum corneum of the skin was measured using a conductance meter (IBS).
SKICON-200). The conductance was determined by averaging the measured values five times and expressing the average value of ten subjects. Table 1 shows the obtained results.
【００２２】[0022]
【表１】 [Table 1]
【００２３】表１より本発明のビフィドバクテリウム属
による発酵豆乳は、優れた皮膚角質層の水分保持機能を
有しており、保湿剤として有用であることがわかる。ま
た、このとき「べたつき」はほとんど感じられなかっ
た。From Table 1, it can be seen that the fermented soymilk produced by the genus Bifidobacterium of the present invention has an excellent function of retaining moisture in the stratum corneum of the skin and is useful as a humectant. At this time, "stickiness" was hardly felt.
【００２４】試験例２ 試験例１と同様のサンプルにヒアルロン酸（ＨＡ）を
０．３重量％配合して１０μｌ／cm2 皮膚に塗布し、そ
のときのコンダクタンスの経時変化を調べた。得られた
結果を表２に示す。Test Example 2 Hyaluronic acid (HA) was added to the same sample as in Test Example 1 in an amount of 0.3% by weight and applied to the skin at 10 μl / cm 2 . Table 2 shows the obtained results.
【００２５】[0025]
【表２】 [Table 2]
【００２６】表２よりビフィドバクテリウム属による発
酵豆乳にヒアルロン酸を配合すると更に優れた保湿効果
が見られた。According to Table 2, when hyaluronic acid was added to the fermented soybean milk of the genus Bifidobacterium, a more excellent moisturizing effect was observed.
【００２７】実施例１ 下記組成の化粧水を製造した。Example 1 A lotion having the following composition was produced.
【００２８】[0028]
【表３】 （重量％） （１）エタノール ５．０ （２）１，３−ブチレングリコール ２．０ （３）ヒアルロン酸 ０．２ （４）ポリオキシエチレン硬化ヒマシ油 ０．０５ （５）パラオキシ安息香酸メチル ０．１ （６）香料 ０．１ （７）豆乳発酵生成物（試験例１のもの） 全体で１００となる量(Table 3) (% by weight) (1) Ethanol 5.0 (2) 1,3-butylene glycol 2.0 (3) Hyaluronic acid 0.2 (4) Polyoxyethylene hydrogenated castor oil 0.05 (5) Methyl paraoxybenzoate 0.1 (6) Fragrance 0.1 (7) Fermented soymilk product (of Test Example 1) Amount of 100 in total
【００２９】製法：（７）に（３）を分散し、これに
（１）、（２）、（４）、（５）及び（６）を加えて十
分攪拌することにより化粧水を得た。Production method: (3) was dispersed in (7), (1), (2), (4), (5) and (6) were added thereto, and the mixture was sufficiently stirred to obtain a lotion. .
【００３０】実施例２ 下記組成の乳液を製造した。Example 2 An emulsion having the following composition was produced.
【００３１】[0031]
【表４】 （重量％） （１）ステアリン酸 ２．０ （２）流動パラフィン ５．０ （３）スクワラン ２．０ （４）ソルビタンモノステアレート １．５ （５）ポリオキシエチレン（２０）ソルビタン モノステアレート ２．０ （６）パラオキシ安息香酸ブチル ０．０５ （７）グリセリン ２．０ （８）パラオキシ安息香酸メチル ０．１ （９）香料 ０．１５ （10）豆乳発酵生成物（試験例１のもの） 全体で１００となる量(% By weight) (1) Stearic acid 2.0 (2) Liquid paraffin 5.0 (3) Squalane 2.0 (4) Sorbitan monostearate 1.5 (5) Polyoxyethylene (20) Sorbitan monostearate 2.0 (6) Butyl paraoxybenzoate 0.05 (7) Glycerin 2.0 (8) Methyl paraoxybenzoate 0.1 (9) Fragrance 0.15 (10) Fermented product of soymilk (test Example 1) Total amount of 100
【００３２】製法：（１０）に（７）及び（８）を加
え、これに８０℃で（１）〜（６）を加えて乳化し、そ
の後（９）を加えて室温まで冷却して乳液を得た。Production method: (7) and (8) are added to (10), and (1) to (6) are added to this at 80 ° C. to emulsify. Then, (9) is added and the mixture is cooled to room temperature to obtain an emulsion. I got
【００３３】実施例３ 下記組成のクリームを製造した。Example 3 A cream having the following composition was produced.
【００３４】[0034]
【表５】 （重量％） （１）流動パラフィン ２３．０ （２）ワセリン ７．０ （３）セタノール １．０ （４）ステアリン酸 ２．０ （５）ミツロウ ２．０ （６）ソルビタンモノステアレート ３．５ （７）ポリオキシエチレン（２０）ソルビタンモノ ステアレート ２．５ （８）パラオキシ安息香酸ブチル ０．０５ （９）ヒアルロン酸 ０．１ （10）１，３−ブチレングリコール １．０ （11）パラオキシ安息香酸メチル ０．１ （12）香料 ０．１５ （13）乳酸菌培養液 ５．０ （14）豆乳発酵生成物（試験例１のもの） 全体で１００となる量(% By weight) (1) Liquid paraffin 23.0 (2) Vaseline 7.0 (3) Cetanol 1.0 (4) Stearic acid 2.0 (5) Beeswax 2.0 (6) Sorbitan mono Stearate 3.5 (7) Polyoxyethylene (20) sorbitan monostearate 2.5 (8) Butyl paraoxybenzoate 0.05 (9) Hyaluronic acid 0.1 (10) 1,3-butylene glycol 1. 0 (11) Methyl parahydroxybenzoate 0.1 (12) Fragrance 0.15 (13) Culture solution of lactic acid bacteria 5.0 (14) Fermented product of soymilk (of Test Example 1) Amount to be 100 in total
【００３５】製法：（１４）に（１３）、（１０）及び
（１１）を加え、これに（９）を分散せしめて分散液を
得る。次いでこれを８０℃で（１）〜（８）を加えて乳
化し、その後（１２）を加えて室温まで冷却してクリー
ムを得た。Production method: (13), (10) and (11) are added to (14), and (9) is dispersed therein to obtain a dispersion. Next, this was emulsified by adding (1) to (8) at 80 ° C., and then adding (12) and cooling to room temperature to obtain a cream.
───────────────────────────────────────────────────── フロントページの続き (72)発明者 大脇 真 東京都港区東新橋１−１−19 株式会社 ヤクルト本社内 (72)発明者 横倉 輝男 東京都港区東新橋１−１−19 株式会社 ヤクルト本社内 (56)参考文献 特開 平３−41019（ＪＰ，Ａ) 特開 平６−65041（ＪＰ，Ａ) 特開 平６−128140（ＪＰ，Ａ) 特開 平11−75828（ＪＰ，Ａ) 特表 昭57−500830（ＪＰ，Ａ) (58)調査した分野(Int.Cl.7，ＤＢ名) A61K 7/00 - 7/50 A61K 35/74 C12N 1/00 - 1/38 C12P 1/00 - 1/06 ──────────────────────────────────────────────────続 き Continued on the front page (72) Inventor Makoto Owaki 1-1-19 Higashi-Shimbashi, Minato-ku, Tokyo Yakult Honsha (72) Inventor Teruo Yokokura 1-1-19, Higashi-Shimbashi, Minato-ku, Tokyo Yakult Honsha (56) References JP-A-3-41019 (JP, A) JP-A-6-65041 (JP, A) JP-A-6-128140 (JP, A) JP-A-11-75828 (JP, A A) Special table 57-500830 (JP, A) (58) Fields investigated (Int. Cl. 7 , DB name) A61K 7/ 00-7/50 A61K 35/74 C12N 1/00-1/38 C12P 1/00-1/06
Claims (3)
種又は２種以上の微生物を豆乳に作用させて得られる発
酵生成物を有効成分とする保湿剤。1. A member selected from the genus Bifidobacterium
A humectant comprising, as an active ingredient, a fermentation product obtained by allowing a seed or two or more microorganisms to act on soymilk.
料。2. A cosmetic comprising the humectant according to claim 1.
を含有する化粧料。3. A cosmetic comprising the humectant according to claim 1 and hyaluronic acid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP09233797A JP3184114B2 (en) | 1997-04-10 | 1997-04-10 | Moisturizer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP09233797A JP3184114B2 (en) | 1997-04-10 | 1997-04-10 | Moisturizer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH10287540A JPH10287540A (en) | 1998-10-27 |
| JP3184114B2 true JP3184114B2 (en) | 2001-07-09 |
Family
ID=14051590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP09233797A Expired - Lifetime JP3184114B2 (en) | 1997-04-10 | 1997-04-10 | Moisturizer |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3184114B2 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004064712A3 (en) * | 2003-01-17 | 2005-03-03 | Beiersdorf Ag | Preparations containing bean sprout extracts combined with vitamin c and/or e and/or $g(a)-glycosylrutin |
| JP2019147765A (en) * | 2018-02-27 | 2019-09-05 | 株式会社ヤクルト本社 | Cleansing cosmetic |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000021501A1 (en) * | 1998-10-09 | 2000-04-20 | Kabushiki Kaisha Yakult Honsha | Skin preparations for external use |
| JP4612183B2 (en) * | 2000-12-27 | 2011-01-12 | 株式会社ヤクルト本社 | External composition for skin and method for producing the same |
| BR0116679A (en) | 2000-12-19 | 2004-01-13 | Yakult Honsha Kk | Skin preparations for external application and process for manufacture |
| JP4612180B2 (en) * | 2000-12-19 | 2011-01-12 | 株式会社ヤクルト本社 | Skin preparation |
| JP2002265343A (en) * | 2001-03-07 | 2002-09-18 | Ichimaru Pharcos Co Ltd | Cosmetic composition |
| GB0513193D0 (en) * | 2005-06-29 | 2005-08-03 | Quest Int Serv Bv | Improvements in skin and hair care |
| JP5048935B2 (en) * | 2005-08-24 | 2012-10-17 | 株式会社ヤクルト本社 | Moisturizer |
| JP7179328B2 (en) * | 2018-12-20 | 2022-11-29 | 株式会社光英科学研究所 | Skin moisturizing agent for oral administration |
-
1997
- 1997-04-10 JP JP09233797A patent/JP3184114B2/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004064712A3 (en) * | 2003-01-17 | 2005-03-03 | Beiersdorf Ag | Preparations containing bean sprout extracts combined with vitamin c and/or e and/or $g(a)-glycosylrutin |
| JP2019147765A (en) * | 2018-02-27 | 2019-09-05 | 株式会社ヤクルト本社 | Cleansing cosmetic |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10287540A (en) | 1998-10-27 |
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