JP2909758B2 - Cosmetics - Google Patents
CosmeticsInfo
- Publication number
- JP2909758B2 JP2909758B2 JP12904290A JP12904290A JP2909758B2 JP 2909758 B2 JP2909758 B2 JP 2909758B2 JP 12904290 A JP12904290 A JP 12904290A JP 12904290 A JP12904290 A JP 12904290A JP 2909758 B2 JP2909758 B2 JP 2909758B2
- Authority
- JP
- Japan
- Prior art keywords
- glycyrrhizin
- glycyrrhetinic acid
- cosmetic
- emulsifier
- acid monoglucuronide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Cosmetics (AREA)
Description
【発明の詳細な説明】 〔産業上の利用分野〕 本発明は、クリーム状ないし乳液状の化粧料に関する
ものである。Description: TECHNICAL FIELD The present invention relates to a creamy or milky cosmetic.
クリーム、乳液など、乳化型化粧料に従来使われてき
た界面活性剤は多数あるが、合成界面活性剤は皮膚刺激
性を有するものが多いため、最近は天然物系のものが望
まれるようになってきた。しかしながら、化粧料に用い
る界面活性剤は、皮膚を刺激しないことはもちろん、感
触、流動性、使用性、安定性等に優れ、外観（きめ、光
沢）も良好な化粧料を与えなければならず、これら多様
な要求に応え得るものは少ない。There are many surfactants conventionally used in emulsified cosmetics such as creams and emulsions, but many of synthetic surfactants have skin irritation properties. It has become. However, surfactants used in cosmetics must not only irritate the skin, but also provide cosmetics with excellent feel, fluidity, usability, stability, etc., and good appearance (texture, gloss). However, few can meet these various requirements.
甘草から抽出されるグリチルリチンは安全性の高い天
然物系界面活性物質の一つとして知られているが、pH5.
5以下の酸性水系では粘度上昇やゲル化を起こす欠点が
あり、さらに、泡立ち易く、一旦泡立つと長時間泡が消
えないという欠点もある。これらの欠点により、グリチ
ルリチンを主要乳化剤とする化粧料の処方設計は困難な
ことが多い。Glycyrrhizin extracted from licorice is known as one of the highly safe natural surfactants, but pH 5.
An acidic aqueous system having a viscosity of 5 or less has a drawback of causing an increase in viscosity and gelling, and further has a drawback that bubbles are easily formed and once foamed, bubbles do not disappear for a long time. Due to these drawbacks, it is often difficult to formulate a cosmetic formulation using glycyrrhizin as the main emulsifier.
本発明の目的は、上述のような現状に鑑み、安全でし
かも使い易い天然物系界面活性物質により油性成分が乳
化された化粧料を提供することにある。An object of the present invention is to provide a cosmetic in which an oily component is emulsified by a safe and easy-to-use natural-based surfactant in view of the above-mentioned situation.
本発明の他の目的は、上記目的達成のための天然物系
界面活性物質をグリチルリチン誘導体の中から見いだす
ことにある。Another object of the present invention is to find a natural surfactant substance for achieving the above object from glycyrrhizin derivatives.
上記目的は、グリチルレチン酸モノグルクロナイドの
すぐれた特性を見いだしたことにより達成された。すな
わち、本発明は乳化剤としてグリチルレチン酸モノグル
クロナイドまたはこれとグリチルリチンとを用いて油性
物質を乳化してなるクリーム状ないし乳液状の化粧料を
提供するものである。The above object has been achieved by finding excellent properties of glycyrrhetinic acid monoglucuronide. That is, the present invention provides a creamy or emulsified cosmetic obtained by emulsifying an oily substance using glycyrrhetinic acid monoglucuronide or glycyrrhizin as an emulsifier.
グリチルレチン酸モノグルクロナイドは、クリチルリ
チンを酵素的に部分加水分解して糖部のグルクロン酸２
分子のうち１分子を除くことにより得られる物質である
が、その界面活性その他の溶液特性は従来ほとんど知ら
れていなかった。グリチルリチンと比較した場合のその
特徴は次のとおりである。Glycyrrhetinic acid monoglucuronide is enzymatically partially hydrolyzed to glycyrrhizin to form glucuronic acid 2 in the sugar moiety.
Although it is a substance obtained by removing one molecule from the molecule, its surface activity and other solution properties have not been known so far. Its characteristics when compared to glycyrrhizin are as follows.
甘草から抽出されるグリチルリチンの水溶液は、酸
性域では経時的に粘度上昇を起こす。そして、濃度が高
い場合にはゲル化を起こすが、グリチルレチン酸モノグ
ルクロナイドの溶液は酸性域でも安定している。The aqueous solution of glycyrrhizin extracted from licorice increases in viscosity with time in an acidic region. When the concentration is high, gelation occurs, but the solution of glycyrrhetinic acid monoglucuronide is stable even in an acidic region.
水溶液の泡が消え易い。 The bubbles of the aqueous solution are easy to disappear.
乳化能はグリチルリチンのそれとほぼ同等である。 The emulsifying ability is almost the same as that of glycyrrhizin.
このような有利な性質を有することにより、グリチル
レチン酸モノグルクロナイドを乳化剤に採用するときは
十分量を使用して安定かつ品質良好な化粧料を容易に製
造することができる。By having such advantageous properties, when glycyrrhetinic acid monoglucuronide is employed as an emulsifier, a stable and good-quality cosmetic can be easily produced using a sufficient amount.
本発明において用いるグリチルレチン酸モノグルクロ
ナイドは、遊離酸のほか、モノアンモニウム塩、モノカ
リウム塩、モノナトリウム塩、ジカリウム塩、ジナトリ
ウム塩等であってもよい。The glycyrrhetinic acid monoglucuronide used in the present invention may be a free acid, a monoammonium salt, a monopotassium salt, a monosodium salt, a dipotassium salt, a disodium salt, or the like.
本発明においてはグリチルレチン酸モノグルクロナイ
ドにグリチルリチンを必要に応じて併用することができ
るが、併用するグリチルリチンとしても、遊離酸のほ
か、モノアンモニウム塩、モノカリウム塩、モノナトリ
ウム塩、ジカリウム塩、ジナトリウム塩等を使用するこ
とができる。ただし、その併用量は、グリチルレチン酸
モノグルクロナイドとの合計量の70モル％を超えないこ
とが望ましい。In the present invention, glycyrrhizin may be used in combination with glycyrrhetinic acid monoglucuronide as necessary.As the glycyrrhizin used in combination, other than free acids, monoammonium salts, monopotassium salts, monosodium salts, dipotassium salts, Disodium salts and the like can be used. However, it is desirable that the combined amount does not exceed 70 mol% of the total amount with glycyrrhetinic acid monoglucuronide.
グリチルレチン酸モノグルクロナイドは、化粧料製造
原料の種類や配合比に応じて化粧料中に0.01〜20重量％
含有させることができるが、一般的には、0.1〜５重量
％の範囲で含有させることが望ましい。Glycyrrhetinic acid monoglucuronide is present in the cosmetic in an amount of 0.01 to 20% by weight, depending on the type and the mixing ratio of the raw material for the cosmetic
Although it can be contained, it is generally desirable to contain it in the range of 0.1 to 5% by weight.
グリチルレチン酸モノグルクロナイドまたはこれとグ
リチルリチンとの混合物は、油性化粧料に通常使われる
油性物質、すなわち高級脂肪族炭化水素類、動物油脂
類、植物油脂類、ロウ類、高級アルコール類、高級脂肪
酸エステル油、シリコーン油等のほとんどを、きわめて
好ましい状態に乳化させる。Glycyrrhetinic acid monoglucuronide or a mixture of glycyrrhizin and glycyrrhizin are oily substances usually used in oily cosmetics, that is, higher aliphatic hydrocarbons, animal oils and fats, vegetable oils and fats, waxes, higher alcohols and higher fatty acids. Most of the ester oils, silicone oils, etc. are emulsified in a very favorable state.
乳化剤としてグリチルレチン酸モノグルクロナイドを
用いても、化粧料の他の原料および製造工程に特別のも
のは必要としない。しかしながら、油性物質の配合量が
特に多い場合、あるいは乳化が特に困難な油性物質を用
いた場合は、必要に応じてレシチン、シュガーエステ
ル、カゼインソーダ、Ｎ−アシルグルタミン酸、ペクチ
ン、キサンタンガム、カラヤガム、ローカストビーンガ
ム等の天然物系界面活性物質を併用することができる。Even if glycyrrhetinic acid monoglucuronide is used as an emulsifier, no special ingredients are required for other raw materials and manufacturing steps of the cosmetic. However, when the compounding amount of the oily substance is particularly large, or when an oily substance which is particularly difficult to emulsify is used, lecithin, sugar ester, casein soda, N-acylglutamic acid, pectin, xanthan gum, karaya gum, locust A natural surfactant such as bean gum can be used in combination.
実施例1:スキンクリーム 処方： 1.セチルアルコール 17重量部 2.ミリスチン酸イソセチル 12 3.スクワラン ３ 4.流動パラフィン 22 5.乳化剤 ５ 6.メチルパラベン 0.2 7.プロピレングリコール ６ 8.純水 34.6 9.香料 0.2 乳化剤としては、グリチルレチン酸モノグルクロナイ
ドモノアンモニウムとグリチルリチン酸モノアンモニウ
ムのモル比51:49の混合物を用いる。Example 1: Skin cream Formulation: 1. Cetyl alcohol 17 parts by weight 2. Isocetyl myristate 12 3. Squalane 3 4. Liquid paraffin 22 5. Emulsifier 5 6. Methyl paraben 0.2 7. Propylene glycol 6 8. Pure water 34.6 9. Perfume 0.2 As the emulsifier, a mixture of monoammonium glycyrrhetinate monoammonium and ammonium glycyrrhizinate in a molar ratio of 51:49 is used.
上記成分中、油性成分の１〜４を80℃で均一に混合
し、別に水溶性成分５〜７を80℃で純水に溶解した。得
られた水溶性成分水溶液をホモミキサーで撹拌し、そこ
に油性成分混合物を添加して乳化させ、70℃まで冷却し
てから香料を添加し、30℃に降温後、撹拌を停止した。Among the above components, oil components 1 to 4 were uniformly mixed at 80 ° C, and water soluble components 5 to 7 were separately dissolved in pure water at 80 ° C. The obtained aqueous solution of the water-soluble component was stirred with a homomixer, and the oil-based component mixture was added to emulsify the mixture. After cooling to 70 ° C., a fragrance was added, and after the temperature was lowered to 30 ° C., the stirring was stopped.
得られたスキンクリームはO/W型のエマルジョンで、
肌目、光沢等の外観がよく、５〜45℃の恒温槽内で３カ
月保存後も乳化状態に変化は認められず、きわめて安定
なものであった。The resulting skin cream is an O / W type emulsion,
The appearance, such as texture and gloss, was good, and no change was observed in the emulsified state even after storage in a thermostat at 5 to 45 ° C. for 3 months, and the product was extremely stable.
実施例２ 実施例１の処方の乳化剤におけるグリチルレチン酸モ
ノグルクロナイドモノアンモニウム：グリチルリチン酸
モノアンモニウムのモル比を種々変更してスキンクリー
ムを製造し、その外観および安定性を同様にして判定し
た。その結果は次のとおりであった。モル比 外観 安定性 100:0 良好 安定 60:40 良好 安定 30:70 良好 安定 0:100 ゲル化が起こり、肌なじみが悪い。硬化していく。Example 2 A skin cream was produced by changing the molar ratio of monoammonium glycyrrhetinate monoammonium glycyrrhetinate: monoammonium glycyrrhizinate in the emulsifier of the formulation of Example 1, and the appearance and stability were similarly determined. The results were as follows. Molar ratio appearance stability 100: 0 Good Stable 60:40 Good Stable 30:70 Good Stable 0: 100 Gelation occurs and skin adaptation is poor. Hardens.
乳化剤としてグリチルレチン酸モノグルクロナイドを
用いる本発明の化粧料は、長期間保存しても粘度変化が
ほとんどなく、初期性状を安定に保つ。また、泡立ちが
少なく、消泡速度も早いので、製造過程で泡立ちに対す
る対策を簡単に済ませることができる。The cosmetic of the present invention using glycyrrhetinic acid monoglucuronide as an emulsifier hardly changes in viscosity even after long-term storage, and keeps its initial properties stable. Further, since there is little foaming and the defoaming speed is high, it is possible to easily take measures against foaming in the manufacturing process.
また、グリチルレチン酸モノグルクロナイドは皮膚を
刺激せず、感触、流動性、使用性、外観等の点でも良好
な化粧料を与える。In addition, glycyrrhetinic acid monoglucuronide does not irritate the skin and gives a good cosmetic in terms of feel, fluidity, usability, appearance and the like.
Claims (1)
ロナイドまたはこれとグリチルリチンとを用いて油性物
質を乳化してなるクリーム状ないし乳液状の化粧料。1. A creamy or emulsion-like cosmetic obtained by emulsifying an oily substance using glycyrrhetinic acid monoglucuronide or glycyrrhizin as an emulsifier.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12904290A JP2909758B2 (en) | 1990-05-21 | 1990-05-21 | Cosmetics |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12904290A JP2909758B2 (en) | 1990-05-21 | 1990-05-21 | Cosmetics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0426607A JPH0426607A (en) | 1992-01-29 |
| JP2909758B2 true JP2909758B2 (en) | 1999-06-23 |
Family
ID=14999658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12904290A Expired - Fee Related JP2909758B2 (en) | 1990-05-21 | 1990-05-21 | Cosmetics |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2909758B2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114246875B (en) * | 2021-12-15 | 2024-05-10 | 亿利耐雀生物科技有限公司 | Anti-inflammatory and freckle-removing compound nicotinamide composition and application thereof |
-
1990
- 1990-05-21 JP JP12904290A patent/JP2909758B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0426607A (en) | 1992-01-29 |
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