JP2023508191A - 薬剤送達装置用の容器ホルダーアセンブリ、および薬剤送達装置 - Google Patents
薬剤送達装置用の容器ホルダーアセンブリ、および薬剤送達装置 Download PDFInfo
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- JP2023508191A JP2023508191A JP2022539227A JP2022539227A JP2023508191A JP 2023508191 A JP2023508191 A JP 2023508191A JP 2022539227 A JP2022539227 A JP 2022539227A JP 2022539227 A JP2022539227 A JP 2022539227A JP 2023508191 A JP2023508191 A JP 2023508191A
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- 238000012377 drug delivery Methods 0.000 title claims abstract description 44
- 238000002347 injection Methods 0.000 claims abstract description 23
- 239000007924 injection Substances 0.000 claims abstract description 23
- 239000003814 drug Substances 0.000 claims description 33
- 239000012528 membrane Substances 0.000 claims description 8
- 239000000126 substance Substances 0.000 claims description 6
- 229940079593 drug Drugs 0.000 description 18
- 230000004888 barrier function Effects 0.000 description 8
- 230000036512 infertility Effects 0.000 description 4
- 239000013043 chemical agent Substances 0.000 description 3
- 239000003085 diluting agent Substances 0.000 description 3
- 238000006073 displacement reaction Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000015556 catabolic process Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000037452 priming Effects 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000005755 formation reaction Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000008177 pharmaceutical agent Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
- A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3293—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle hub
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
- A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
- A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
- A61M2005/2474—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase with movable piercing means, e.g. ampoule remains fixed or steady
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/31581—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by rotationally moving or pivoting actuator operated by user, e.g. an injection lever or handle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/347—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub rotatable, e.g. bayonet or screw
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
12 容器ホルダーアセンブリ
14 アクチュエータ装置
16 長手方向軸
18 容器ホルダー
20 針アセンブリ
22 遠位管状本体
24 近位管状部分
26 遠位本体係合構造
28 第1のインジケータ
30 第2のインジケータ
32 第3のインジケータ
34 翼
36 キャップ
38 開封表示部材
40 近位ハウジング部分
42 遠位ハウジング部分
44 ボタン
46 開口部
48 第1の凹部/係合可能装置機構
50 第2の凹部/係合可能装置機構
52 第3の凹部/係合可能装置機構
54 可撓性タブ/係合本体構造
56 マルチチャンバー容器
58 近位ストッパー
60 遠位ストッパー
62 ハブ
64 注射針
66 針カバー
68 クラッチ
70 ハウジング係合構造
72 アクチュエータ
74 アクチュエータスリーブ
76 ロッキングスプリング
78 プランジャロッド
80 プランジャスプリング
82 ガイドロッド
84 近位針端
86 遠位針端
88 膜
90 滅菌バリア
92 近位本体係合構造
94 遠位カバー係合構造
96 近位内部係合構造
98 遠位外部係合構造
100 近位外部溝
102 内側リブ
104 矢印
106 フック
108 ストップ
110 可撓性アーム
112 突起
114 溝
Claims (14)
- 薬剤送達装置(10)用の容器ホルダーアセンブリ(12)であって、前記容器ホルダーアセンブリ(12)は、容器ホルダー(18)および針アセンブリ(20)を備え、前記容器ホルダー(18)は、
マルチチャンバー容器(56)を中に受容する遠位管状本体(22)であって、前記遠位管状本体(22)は、外面と、前記容器ホルダー(18)をアクチュエータ装置(14)に解放可能に接続するために、前記薬剤送達装置(10)の前記アクチュエータ装置(14)に移動可能に係合するように前記外面に構成された遠位本体係合構造(26)と、を備える遠位管状本体(22)と、
前記針アセンブリ(20)に接続された近位本体係合構造(92)を備える近位管状部分(24)であって、前記マルチチャンバー容器(56)が前記遠位管状本体(22)内に受容される前に前記針アセンブリ(20)が前記容器ホルダー(18)に事前に組み立てられている、近位管状部分(24)と、
を備え、
前記針アセンブリ(20)は、遠位針端(86)および近位針端(84)を有する注射針(64)を有するハブ(62)を備え、前記マルチチャンバー容器(56)が前記遠位管状本体(22)内に受容される場合に、前記遠位針端(86)は、前記マルチチャンバー容器(56)から隔離されている、容器ホルダーアセンブリ(12)。 - 前記遠位管状本体(22)は、前記容器ホルダーアセンブリ(12)の長手方向軸(16)に沿って長く伸びている、請求項1に記載の容器ホルダーアセンブリ(12)。
- 前記遠位本体係合構造(26)は、雄ねじである、請求項1または2に記載の容器ホルダーアセンブリ(12)。
- 前記遠位本体係合構造(26)は、前記薬剤送達装置(10)のハウジング部分(40)にねじ式に係合するよう構成されている、請求項1~3のいずれか一項に記載の容器ホルダーアセンブリ(12)。
- 前記遠位管状本体(22)は、前記ハウジング部分(40)の少なくとも1つの係合可能装置機構(48,50,52)と解放可能に係合するように構成された少なくとも1つの係合本体構造(54)を備える、請求項4に記載の容器ホルダーアセンブリ(12)。
- 各前記少なくとも1つの係合本体構造(54)は、可撓性突起である、請求項5に記載の容器ホルダーアセンブリ(12)。
- 前記近位本体係合構造(92)は、前記針アセンブリ(20)にねじ式に係合するための雄ねじである、請求項1~6のいずれか一項に記載の容器ホルダーアセンブリ(12)。
- 前記近位管状部分(24)は、前記ハブ(62)にねじ式に係合するための近位内部係合構造(96)を備える、請求項1~7のいずれか一項に記載の容器ホルダーアセンブリ(12)。
- 前記針アセンブリ(20)は、キャップ(36)をさらに備え、前記キャップ(36)は、前記キャップ(36)の手動回転が前記ハブ(62)の軸方向の遠位移動を生じるように構成されている、請求項1~8のいずれか一項に記載の容器ホルダーアセンブリ(12)。
- 前記遠位針端(86)は、前記ハブ(62)の前記軸方向の遠位移動によって前記マルチチャンバー容器(56)の近位端部に配置された膜(88)を貫通するよう構成されている、請求項9に記載の容器ホルダーアセンブリ(12)。
- 前記針アセンブリ(20)は、前記注射針(64)をカバーする針カバー(66)をさらに備え、前記針カバー(66)は、前記近位管状部分(24)を前記針アセンブリ(20)に接続するために、前記近位本体係合構造(92)に係合する遠位カバー係合構造(94)を備える、請求項1~10のいずれか一項に記載の容器ホルダーアセンブリ(12)。
- 前記針アセンブリ(20)は、開封表示部材(38)をさらに備える、請求項1~11のいずれか一項に記載の容器ホルダーアセンブリ(12)。
- 請求項1~12のいずれか一項に記載の容器ホルダーアセンブリ(12)を備える薬剤送達装置(10)。
- ハウジング部分(40)を有するアクチュエータ装置(14)をさらに備え、前記薬剤送達装置(10)は、前記容器ホルダー(18)を前記ハウジング部分(40)内に手動で動かすことにより、前記マルチチャンバー容器(56)内の少なくとも2つの物質の混合を引きおこすように構成されている、請求項13に記載の薬剤送達装置(10)。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202062965175P | 2020-01-24 | 2020-01-24 | |
US62/965,175 | 2020-01-24 | ||
EP20166553 | 2020-03-30 | ||
EP20166553.6 | 2020-03-30 | ||
PCT/EP2020/084054 WO2021148176A1 (en) | 2020-01-24 | 2020-12-01 | Container holder assembly for medicament delivery device, and medicament delivery device |
Publications (1)
Publication Number | Publication Date |
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JP2023508191A true JP2023508191A (ja) | 2023-03-01 |
Family
ID=73554460
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2022539227A Pending JP2023508191A (ja) | 2020-01-24 | 2020-12-01 | 薬剤送達装置用の容器ホルダーアセンブリ、および薬剤送達装置 |
Country Status (6)
Country | Link |
---|---|
US (1) | US20220409803A1 (ja) |
EP (1) | EP4093464A1 (ja) |
JP (1) | JP2023508191A (ja) |
KR (1) | KR20220119116A (ja) |
CN (1) | CN114728128B (ja) |
WO (1) | WO2021148176A1 (ja) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110230827A1 (en) * | 2008-05-24 | 2011-09-22 | Kevin Mori | Mixing device for a two-chamber ampoule |
US20140243741A1 (en) * | 2011-11-03 | 2014-08-28 | Tecpharma Licensing Ag | Administration device for mixing an active substance with a dilution liquid |
JP2015534867A (ja) * | 2012-11-19 | 2015-12-07 | ケアベイ・ヨーロッパ・リミテッドCarebay Europe Limited | 注射針アセンブリ |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102802699B (zh) * | 2009-04-24 | 2014-10-22 | Shl集团有限责任公司 | 药物递送装置 |
TWI464002B (zh) * | 2010-11-08 | 2014-12-11 | Shl Group Ab | 容器支撐總成和藥物輸送裝置總成 |
US9072839B2 (en) * | 2010-11-29 | 2015-07-07 | Sanofi-Aventis Deutschland Gmbh | Automatic delivery device with triggering mechanism |
WO2013048310A1 (en) * | 2011-09-27 | 2013-04-04 | Shl Group Ab | Medical delivery device with an initial locked state, intermediate priming state and a medicament delivery state |
TWI569841B (zh) * | 2013-10-10 | 2017-02-11 | 卡貝歐洲有限公司 | 藥物輸送裝置 |
-
2020
- 2020-12-01 JP JP2022539227A patent/JP2023508191A/ja active Pending
- 2020-12-01 WO PCT/EP2020/084054 patent/WO2021148176A1/en unknown
- 2020-12-01 KR KR1020227025175A patent/KR20220119116A/ko not_active Application Discontinuation
- 2020-12-01 EP EP20812098.0A patent/EP4093464A1/en active Pending
- 2020-12-01 US US17/775,651 patent/US20220409803A1/en active Pending
- 2020-12-01 CN CN202080082336.0A patent/CN114728128B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110230827A1 (en) * | 2008-05-24 | 2011-09-22 | Kevin Mori | Mixing device for a two-chamber ampoule |
US20140243741A1 (en) * | 2011-11-03 | 2014-08-28 | Tecpharma Licensing Ag | Administration device for mixing an active substance with a dilution liquid |
JP2015534867A (ja) * | 2012-11-19 | 2015-12-07 | ケアベイ・ヨーロッパ・リミテッドCarebay Europe Limited | 注射針アセンブリ |
Also Published As
Publication number | Publication date |
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US20220409803A1 (en) | 2022-12-29 |
KR20220119116A (ko) | 2022-08-26 |
WO2021148176A1 (en) | 2021-07-29 |
EP4093464A1 (en) | 2022-11-30 |
CN114728128B (zh) | 2024-05-14 |
CN114728128A (zh) | 2022-07-08 |
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