JP2021004206A - Skin cleansing composition - Google Patents
Skin cleansing composition Download PDFInfo
- Publication number
- JP2021004206A JP2021004206A JP2019118268A JP2019118268A JP2021004206A JP 2021004206 A JP2021004206 A JP 2021004206A JP 2019118268 A JP2019118268 A JP 2019118268A JP 2019118268 A JP2019118268 A JP 2019118268A JP 2021004206 A JP2021004206 A JP 2021004206A
- Authority
- JP
- Japan
- Prior art keywords
- skin
- acid
- cleansing composition
- feeling
- skin cleansing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/04—Carboxylic acids or salts thereof
- C11D1/10—Amino carboxylic acids; Imino carboxylic acids; Fatty acid condensates thereof
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/74—Carboxylates or sulfonates esters of polyoxyalkylene glycols
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
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- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
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- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
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Abstract
Description
本発明は、洗い上がりの皮膚における平滑感、保湿感、及び柔軟感が総合的に優れた皮膚洗浄料組成物に関する。 The present invention relates to a skin cleansing composition having an overall excellent smoothness, moisturizing feeling, and softness on the washed skin.
皮膚を洗浄し、肌を清潔に保つことを目的とした製品として、洗顔料、ボディソープ、シャンプー等の様々な皮膚洗浄料組成物が提供されている。皮膚洗浄料組成物には、泡立ちの良さ、洗浄力の良さに加えて、使用感の良さが求められている。 Various skin cleansing compositions such as facial cleansers, body soaps, and shampoos are provided as products for the purpose of cleaning the skin and keeping the skin clean. The skin cleansing composition is required to have good foaming property, good cleansing power, and good usability.
使用感の良さの1つとして、肌の平滑感(つるつる感)は洗いあがりの良さを感じさせる特性であり、特に重要視される。例えば、特許文献1には、脂肪酸せっけん、両性界面活性剤またはアルカノールアミド型非イオン性界面活性剤、木通(モクツウ)またはレンゲソウの抽出エキスを含有する洗浄剤組成物が、洗浄後の肌のはり感及び肌のつるつる感に優れることが記載されている。特許文献2には、脂肪酸塩と、アシルイセチオン酸塩と、融点30〜100℃のロウ、炭化水素、及びグリセリドから選択される少なくとも1つである固体脂とを含む固形洗浄剤組成物が、すすぎ時のつるつる感に優れることが記載されている。特許文献3には、アニオン界面活性剤、アルキルエーテルカルボン酸又はその塩、2−エチルヘキシルグリセリルエーテル、及び水を含有する皮膚洗浄剤組成物が、洗浄後の肌のつるつる感に優れることが記載されている。 As one of the good feelings of use, the smoothness of the skin (smoothness) is a characteristic that makes the skin feel good after washing, and is particularly important. For example, in Patent Document 1, a cleansing composition containing an extract of fatty acid soap, an amphoteric surfactant or an alkanolamide-type nonionic surfactant, and an extract of Mokutsu or Rengesou is used for the cleansed skin. It is described that it has excellent elasticity and smoothness of the skin. In Patent Document 2, a solid cleaning composition containing a fatty acid salt, an acyl acetylionate, and a solid fat which is at least one selected from wax having a melting point of 30 to 100 ° C., a hydrocarbon, and a glyceride is rinsed. It is described that it is excellent in the slippery feeling of time. Patent Document 3 describes that a skin cleansing composition containing an anionic surfactant, an alkyl ether carboxylic acid or a salt thereof, 2-ethylhexyl glyceryl ether, and water is excellent in the smooth feeling of the skin after washing. ing.
肌のつるつるとした平滑感を求める皮膚洗浄剤組成物は、さっぱりした洗いあがり感が得られる一方で、使用後の肌における保湿感や柔軟感は失われやすい。つまり、これまでの皮膚洗浄用組成物では、使用後の肌におけるつるつるとした平滑感を、しっとりとした保湿感及びふっくらとした柔軟感と並立できておらず、この点で、総合的な使用感に優れたものとはいえない。 A skin cleansing composition that requires a smooth and smooth feeling on the skin gives a refreshing feeling after washing, but tends to lose the moisturizing feeling and softness on the skin after use. In other words, the conventional skin cleansing compositions have not been able to make the smooth and smooth feeling on the skin after use parallel with the moisturizing feeling and the plump softness, and in this respect, it is used comprehensively. It cannot be said that the feeling is excellent.
そこで本発明は、洗い上がりの皮膚における平滑感、保湿感、及び柔軟感が総合的に優れた皮膚洗浄料組成物を提供することを目的とする。 Therefore, an object of the present invention is to provide a skin cleansing composition having an overall excellent smoothness, moisturizing feeling, and softness on the washed skin.
本発明者は鋭意検討の結果、皮膚洗浄料組成物において、アミノ酸系界面活性剤とともに、両親媒性エステルとカチオン化ヒアルロン酸及び/又はその塩とを配合し、更に、セラミド類を配合することで、洗い上がりの皮膚におけるつるつるとした平滑感とともに、しっとりとした保湿感及びふっくらとした柔軟感も良好に発揮されることを見出した。本発明は、この知見に基づいてさらに検討を重ねることにより完成したものである。 As a result of diligent studies, the present inventor has added an amphipathic ester and cationized hyaluronic acid and / or a salt thereof together with an amino acid-based surfactant in a skin cleansing composition, and further added ceramides. Therefore, it was found that not only a smooth and smooth feeling on the washed skin, but also a moisturizing feeling and a fluffy soft feeling are exhibited well. The present invention has been completed by further studies based on this finding.
即ち、本発明は、下記に掲げる態様の発明を提供する。
項1. (A)アミノ酸系界面活性剤、(B)両親媒性エステル、並びに(C)セラミド、擬似セラミド、及びグリコセラミドからなる群より選択されるセラミド類を含有する、皮膚洗浄料組成物。
項2. 前記(B)成分が、ジカルボン酸ビス(ポリオキシアルキレンアルキルエーテル)エステル、ジカルボン酸ジアルコキシアルキルエステル、及び(エイコサン二酸/テトラデカン二酸)ポリグリセリル−10よりなる群から選ばれる、項1に記載の皮膚洗浄料組成物。
項3. 前記ジカルボン酸ビス(ポリオキシアルキレンアルキルエーテル)エステルが、シクロヘキサン−1,4−ジカルボン酸ビスエトキシジグリコールである、項2に記載の皮膚洗浄料組成物。
項4. 前記(C)成分がグリコセラミドである、請求項1〜3のいずれかに記載の皮膚洗浄料組成物。
項5. さらに、(D)レシチン及び/又はリゾレシチンを含有する、項1〜4のいずれかに記載の皮膚洗浄料組成物。
That is, the present invention provides the inventions of the following aspects.
Item 1. A skin cleansing composition containing (A) an amino acid-based surfactant, (B) an amphipathic ester, and ceramides selected from the group consisting of (C) ceramide, pseudo-ceramide, and glycoceramide.
Item 2. Item 2. The item (B) is selected from the group consisting of a dicarboxylic acid bis (polyoxyalkylene alkyl ether) ester, a dicarboxylic acid dialkoxyalkyl ester, and a (icosane diic acid / tetradecane diic acid) polyglyceryl-10. Skin cleaning composition.
Item 3. Item 2. The skin cleansing composition according to Item 2, wherein the dicarboxylic acid bis (polyoxyalkylene alkyl ether) ester is cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol.
Item 4. The skin cleansing composition according to any one of claims 1 to 3, wherein the component (C) is glycoceramide.
Item 5. Item 2. The skin cleansing composition according to any one of Items 1 to 4, further containing (D) lecithin and / or lysolecithin.
本発明の皮膚洗浄料組成物によれば、洗い上がりの皮膚における平滑感、保湿感、及び柔軟感を総合的に発揮することができる。 According to the skin cleansing composition of the present invention, the smoothness, moisturizing feeling, and softness feeling of the washed skin can be comprehensively exhibited.
本発明の皮膚洗浄料組成物は、(A)アミノ酸系界面活性剤(以下、(A)成分とも記載する)、(B)両親媒性エステル(以下、(B)成分とも記載する)、並びに(C)セラミド、擬似セラミド、及びグリコセラミドからなる群より選択されるセラミド類(以下、(C)成分とも記載する)を含有することを特徴とする。以下、本発明の皮膚洗浄料組成物について詳述する。 The skin cleaning composition of the present invention comprises (A) an amino acid-based surfactant (hereinafter, also referred to as (A) component), (B) an amphipathic ester (hereinafter, also referred to as (B) component), and It is characterized by containing ceramides (hereinafter, also referred to as component (C)) selected from the group consisting of (C) ceramide, pseudo-ceramide, and glycoceramide. Hereinafter, the skin cleansing composition of the present invention will be described in detail.
(A)アミノ酸系界面活性剤
本発明の皮膚洗浄料組成物は、(A)成分としてアミノ酸系界面活性剤を含有する。アミノ酸系界面活性剤を用いることで、皮膚洗浄料組成物が優れた洗浄力を発揮しながらも皮膚刺激を低減することができる。また、(A)成分を(B)成分及び(C)成分と共存させることにより、洗い上がりの皮膚における保湿感及び/又は柔軟感を良好に得ることができる。
(A) Amino Acid-based Surfactant The skin cleansing composition of the present invention contains an amino acid-based surfactant as the component (A). By using an amino acid-based surfactant, the skin cleansing composition can reduce skin irritation while exhibiting excellent cleansing power. Further, by coexisting the component (A) with the component (B) and the component (C), a moisturizing feeling and / or a soft feeling on the washed skin can be satisfactorily obtained.
アミノ酸系界面活性剤としては、洗浄力、皮膚刺激低減性、保湿感及び/又は柔軟感を好ましく得る観点から、アミノ酸系アニオン性界面活性剤及びアミノ酸系両性界面活性剤が挙げられる。アミノ酸系界面活性剤としては、アミノ酸系アニオン性界面活性剤及びアミノ酸系両性界面活性剤のうちいずれか一方を使用してもよいし、両方を組み合わせて使用してもよい。これらのアミノ酸界面活性剤の中でも、平滑感及び保湿感をより好ましく得る観点から、アミノ酸系アニオン性界面活性剤が挙げられ、柔軟感を好ましく得る観点から、アミノ酸系両性界面活性剤が好ましく用いられる。 Examples of the amino acid-based surfactant include an amino acid-based anionic surfactant and an amino acid-based amphoteric surfactant from the viewpoint of preferably obtaining detergency, skin irritation reducing property, moisturizing feeling and / or softness feeling. As the amino acid-based surfactant, either one of the amino acid-based anionic surfactant and the amino acid-based amphoteric surfactant may be used, or both may be used in combination. Among these amino acid surfactants, amino acid-based anionic surfactants are mentioned from the viewpoint of more preferably smoothness and moisturizing feeling, and amino acid-based amphoteric surfactants are preferably used from the viewpoint of preferably obtaining softness. ..
本発明に使用されるアミノ酸系アニオン性界面活性剤としては、カルボン酸型アミノ酸系アニオン性界面活性剤及びスルホン酸型アミノ酸系アニオン性界面活性剤が挙げられる。 Examples of the amino acid-based anionic surfactant used in the present invention include a carboxylic acid-type amino acid-based anionic surfactant and a sulfonic acid-type amino acid-based anionic surfactant.
カルボン酸型アミノ酸系アニオン性界面活性剤としては、オクタノイル基、デカノイル基、ラウロイル基、ミリストイル基、パルミトイル基、ココイル基等の炭素数8〜24の飽和又は不飽和のN−アシル基を有するN−アシルアミノ酸が挙げられる。カルボン酸型アミノ酸系アニオン性界面活性剤におけるN−アシルアミノ酸としては、N−アシルサルコシン、N−アシルアスパラギン酸、N−アシルグルタミン酸、N−アシル−N−メチル−β−アラニン等が挙げられる。より具体的なカルボン酸型アミノ酸系アニオン性界面活性剤としては、N−ラウロイルサルコシン、ココイルサルコシン、N-ラウロイルアスパラギン酸、ココイルアスパラギン酸、N−ラウロイルグルタミン酸、ココイルグルタミン酸、N−ラウロイル−N−メチル−β−アラニン、ココイルメチルアラニン等が挙げられる。 Examples of the carboxylic acid-type amino acid-based anionic surfactant include N having a saturated or unsaturated N-acyl group having 8 to 24 carbon atoms such as an octanoyl group, a decanoyyl group, a lauroyl group, a myritoyl group, a palmitoyl group, and a cocoyl group. -Acyl amino acids can be mentioned. Examples of the N-acyl amino acid in the carboxylic acid type amino acid-based anionic surfactant include N-acylsarcosine, N-acylaspartic acid, N-acylglutamic acid, N-acyl-N-methyl-β-alanine and the like. More specific carboxylic acid-type amino acid-based anionic surfactants include N-lauroyl sarcosine, cocoyl sarcosine, N-lauroyl aspartic acid, cocoyl aspartic acid, N-lauroyl glutamic acid, cocoyl glutamic acid, and N-lauroyl-N-methyl. Examples thereof include -β-alanine and cocoyl methylalanine.
スルホン酸型アミノ酸系アニオン性界面活性剤としては、オクタノイル基、デカノイル基、ラウロイル基、ミリストイル基、パルミトイル基、ココイル基等の炭素数8〜24の飽和又は不飽和のN−アシル基を有するN−アシル−N−メチルタウリンが挙げられる。より具体的なスルホン酸型アミノ酸系アニオン性界面活性剤としては、N−ミリストイル−N−メチルタウリン、N−ラウロイル−N−メチルタウリン、ココイルメチルタウリン等が挙げられる。 Examples of the sulfonic acid-type amino acid-based anionic surfactant include N having a saturated or unsaturated N-acyl group having 8 to 24 carbon atoms such as an octanoyl group, a decanoyyl group, a lauroyl group, a myritoyl group, a palmitoyl group, and a cocoyl group. -Acyl-N-methyltaurine can be mentioned. More specific sulfonic acid-type amino acid-based anionic surfactants include N-myristoyl-N-methyltaurine, N-lauroyl-N-methyltaurine, cocoylmethyltaurine and the like.
なお、これらのアミノ酸系アニオン性界面活性剤は、塩の形態であってもよく、例えば、ナトリウム塩、カリウム塩等のアルカリ金属塩;トリエタノールアミン(TEA)塩;アンモニウム塩等の形態をとることができる。 In addition, these amino acid-based anionic surfactants may be in the form of salts, for example, alkali metal salts such as sodium salt and potassium salt; triethanolamine (TEA) salt; ammonium salt and the like. be able to.
これらのアミノ酸系アニオン性界面活性剤の中でも、洗浄力、皮膚刺激低減性、保湿感及び/又は柔軟感を好ましく得る観点から、好ましくはN-ラウロイルアスパラギン酸、ココイルグルタミン酸、N−ラウロイル−N−メチル−β−アラニン、ココイルメチルアラニン、ココイルメチルタウリンが挙げられ、より好ましくは、N-ラウロイルアスパラギン酸ナトリウム、ココイルグルタミン酸トリエタノールアミン、N−ラウロイル−N−メチル−β−アラニンナトリウム、ココイルメチルアラニンナトリウム、ココイルメチルタウリンナトリウムが挙げられる。洗浄力をより一層好ましく得る観点から、更に好ましくは、N-ラウロイルアスパラギン酸ナトリウム、ココイルグルタミン酸トリエタノールアミン、N−ラウロイル−N−メチル−β−アラニンナトリウム、ココイルメチルアラニンナトリウムが挙げられる。保湿感をより一層好ましく得る観点から、更に好ましくはN-ラウロイルアスパラギン酸ナトリウムが挙げられる。 Among these amino acid-based anionic surfactants, N-lauroyl aspartic acid, cocoyl glutamic acid, and N-lauroyl-N- are preferable from the viewpoint of preferably detergency, skin irritation reduction, moisturizing and / or softness. Methyl-β-alanine, cocoylmethylalanine, cocoylmethyltaurine are mentioned, and more preferably, sodium N-lauroyl aspartate, triethanolamine cocoyl glutamate, N-lauroyl-N-methyl-β-alanine, cocoylmethylalanine. Examples include sodium and cocoyl methyl taurine sodium. From the viewpoint of further preferable detergency, sodium N-lauroyl aspartate, triethanolamine cocoyl glutamate, sodium N-lauroyl-N-methyl-β-alanine, and sodium cocoyl methylalanine can be mentioned more preferably. From the viewpoint of obtaining a more preferable moisturizing feeling, sodium N-lauroyl aspartate is more preferable.
アミノ酸系アニオン性界面活性剤としては、上述のカルボン酸型アミノ酸系アニオン性界面活性剤及びスルホン酸型アミノ酸系アニオン性界面活性剤の中から1種を単独で使用してもよく、また2種以上を組み合わせて使用してもよい。 As the amino acid-based anionic surfactant, one of the above-mentioned carboxylic acid-type amino acid-based anionic surfactant and sulfonic acid-type amino acid-based anionic surfactant may be used alone, or two types may be used. The above may be used in combination.
これらのアミノ酸系アニオン性界面活性剤は、1種単独で使用してもよく、また2種以上を組み合わせて使用してもよい。 These amino acid-based anionic surfactants may be used alone or in combination of two or more.
本発明に使用されるアミノ酸系両性界面活性剤としては、例えば、アミドベタイン型両性界面活性剤およびアルキルベタイン型両性界面活性剤が挙げられる。アミノ酸系両性界面活性剤としては、洗浄力、皮膚刺激低減性、保湿感及び/又は柔軟感をより一層好ましく得る観点から、好ましくはアミドベタイン型両性界面活性剤が挙げられる。 Examples of the amino acid-based amphoteric tenside agent used in the present invention include an amide betaine type amphoteric tenside agent and an alkyl betaine type amphoteric tenside agent. Examples of the amino acid-based amphoteric tenside agent include an amide betaine-type amphoteric tenside agent from the viewpoint of further preferable detergency, skin irritation reduction property, moisturizing feeling and / or softness feeling.
アミドベタイン型両性界面活性剤は、一般式R1CO−NH−(CH2)n−N+(CH3)2CH2CO2 -(式中、R1CO−基は、オクタノイル基、デカノイル基、ラウロイル基、ミリストイル基、パルミトイル基、ココイル基等の炭素数8〜24の飽和又は不飽和のN−アシル基を表し、nは2〜8の整数を表す。)で表される化合物であり、洗浄力、皮膚刺激低減性、保湿感及び/又は柔軟感を好ましく得る観点から、好ましくは、コカミドプロピルベタイン、ラウリル酸アミドプロピルベタイン等が挙げられ、より好ましくは、コカミドプロピルベタインが挙げられる。 Amido betaine type amphoteric surfactants have the general formula R 1 CO-NH- (CH 2 ) n -N + (CH 3) 2 CH 2 CO 2 - ( wherein, R 1 CO- groups, octanoyl group, decanoyl A compound represented by a saturated or unsaturated N-acyl group having 8 to 24 carbon atoms such as a group, a lauroyl group, a myristyl group, a palmitoyl group, and a cocoyl group, and n representing an integer of 2 to 8). From the viewpoint of preferably detergency, reducing skin irritation, moisturizing feeling and / or softness, cocamidopropyl betaine, lauric acid amide propyl betaine and the like are preferable, and cocamidopropyl betaine is more preferable. Can be mentioned.
アルキルベタイン型両性界面活性剤は、一般式R2−N+(CH3)2CH2CO2 -(式中、R2基は、オクチル基、デシル基、ラウリル基、ミリスチル基、パルミチル基、ヤシ油脂肪酸アルキル基等の炭素数8〜24の飽和又は不飽和アルキル基を表す。)で表される化合物であり、洗浄力、皮膚刺激低減性、保湿感及び/又は柔軟感を好ましく得る観点から、好ましくは、ラウリルジメチル酢酸ベタイン、テトラデセルジメチルアミノ酢酸ベタイン等が挙げられる。 Alkyl betaine type amphoteric surfactant has the general formula R 2 -N + (CH 3) 2 CH 2 CO 2 - ( wherein, R 2 groups are octyl, decyl, lauryl group, myristyl group, palmityl group, A compound represented by a saturated or unsaturated alkyl group having 8 to 24 carbon atoms, such as a coconut oil fatty acid alkyl group), from which detergency, skin irritation reduction, moisturizing feeling and / or softness can be preferably obtained. Therefore, preferably, lauryldimethylacetate betaine, tetradeceldimethylaminoacetate betaine and the like can be mentioned.
これらのアミノ酸系両性界面活性剤は、1種単独で使用してもよく、また2種以上を組み合わせて使用してもよい。 These amino acid-based amphoteric surfactants may be used alone or in combination of two or more.
なお、後述するように、本発明の皮膚洗浄料組成物においては(A)成分以外の界面活性剤を含んでもよいが、(D)成分を配合する場合は、より一層向上した柔軟性を得る観点から、(A)成分以外の界面活性剤を含まないことが好ましい。 As will be described later, the skin cleansing composition of the present invention may contain a surfactant other than the component (A), but when the component (D) is blended, further improved flexibility is obtained. From the viewpoint, it is preferable not to contain a surfactant other than the component (A).
本発明の皮膚洗浄料組成物における(A)成分の含有量は特に限定されず、付与すべき洗浄力等に応じて適宜決定すればよいが、例えば、0.025〜20重量%、好ましくは0.025〜12重量%が挙げられる。また、本発明の皮膚洗浄料組成物は、(A)成分が後述の(B)成分と共存していることにより、(A)成分の含有量が少なくても効果的に洗浄力を発揮することができる。このような観点から、皮膚刺激性をさらに低減させるために、(A)成分の含有量の上記範囲の上限としては、例えば10重量%以下、好ましくは6重量%以下、より好ましくは2重量%以下が挙げられる。また、より優れた洗浄力を得る観点からは、(A)成分の上記含有量の上記範囲の下限としては、好ましくは0.05重量%以上、より好ましくは0.1重量%以上、さらに好ましくは0.5重量%以上、一層好ましくは1重量%以上、特に好ましくは1.5重量%以上が挙げられる。また、後述するように、本発明の皮膚洗浄料組成物においては(A)成分以外の界面活性剤を含んでもよいが、(A)成分以外の界面活性剤を含む場合は、(A)成分と(A)成分以外の界面活性剤との含有量の合計が上記範囲内となるように調整されることが好ましい。 The content of the component (A) in the skin cleansing composition of the present invention is not particularly limited and may be appropriately determined according to the cleansing power to be imparted, for example, 0.025 to 20% by weight, preferably 0.025 to 20% by weight. 0.025 to 12% by weight is mentioned. Further, in the skin cleansing composition of the present invention, since the component (A) coexists with the component (B) described later, the skin cleansing composition effectively exhibits detergency even if the content of the component (A) is small. be able to. From this point of view, in order to further reduce skin irritation, the upper limit of the content of the component (A) in the above range is, for example, 10% by weight or less, preferably 6% by weight or less, more preferably 2% by weight. The following can be mentioned. Further, from the viewpoint of obtaining more excellent detergency, the lower limit of the above range of the content of the component (A) is preferably 0.05% by weight or more, more preferably 0.1% by weight or more, still more preferably. Is 0.5% by weight or more, more preferably 1% by weight or more, and particularly preferably 1.5% by weight or more. Further, as will be described later, the skin cleansing composition of the present invention may contain a surfactant other than the component (A), but when a surfactant other than the component (A) is contained, the component (A) is contained. It is preferable that the total content of the surfactant and the surfactant other than the component (A) is adjusted to be within the above range.
(B)両親媒性エステル
本発明の皮膚洗浄料組成物は、(B)成分として両親媒性エステルを含有する。(B)成分を(A)成分及び(C)成分と共存させることにより、洗い上がりの皮膚における保湿感及び柔軟感を良好に得ることができる。
(B) Amphiphilic ester The skin cleansing composition of the present invention contains an amphipathic ester as a component (B). By coexisting the component (B) with the component (A) and the component (C), a moisturizing feeling and a soft feeling on the washed skin can be obtained satisfactorily.
また、(B)成分は単独で洗浄作用を示さないが、(A)成分と共存させることによって、皮膚洗浄料組成物の洗浄力を向上させることもできる。 Further, although the component (B) does not show a cleansing action by itself, the detergency of the skin cleansing composition can be improved by coexisting with the component (A).
本発明において、両親媒性エステルは、日本薬局方一般試験法に定められた方法による測定で、導電率70〜110μs/mに調整されたイオン交換水に常温で2質量%以上溶解し、かつ、油剤であるイソノナン酸イソトリデシル(日清オイリオグループ社製、サラコス913)にも常温(25℃)で10質量%以上溶解するものであり、エステル系界面活性剤は除かれる。 In the present invention, the amphipathic ester is dissolved in ion-exchanged water adjusted to a conductivity of 70 to 110 μs / m by 2% by mass or more at room temperature by the method specified in the General Test Method of the Japanese Pharmacy, and , Isotridecyl isononanoate (manufactured by Nisshin Oillio Group, Saracos 913), which is an oil agent, also dissolves in 10% by mass or more at room temperature (25 ° C.), and ester-based surfactants are excluded.
両親媒性エステルとしては特に限定されないが、保湿感及び洗浄力をより良好に得る観点から、ジカルボン酸ビス(ポリオキシアルキレンアルキルエーテル)エステル、ジカルボン酸ジアルコキシアルキルエステル、及び(エイコサン二酸/テトラデカン二酸)ポリグリセリル−10よりなる群から選ばれるものであることが好ましい。両親媒性エステルとしては、ジカルボン酸ビス(ポリオキシアルキレンアルキルエーテル)エステル、ジカルボン酸ジアルコキシアルキルエステル、及び(エイコサン二酸/テトラデカン二酸)ポリグリセリル−10の中からいずれかを単独で使用してもよく、また2種以上を組み合わせて使用してもよい。これらの両親媒性エステルの中でも、保湿感及び洗浄力をより良好に得る観点から、ジカルボン酸ビス(ポリオキシアルキレンアルキルエーテル)エステルがより好ましい。 The amphoteric ester is not particularly limited, but from the viewpoint of obtaining a better moisturizing feeling and detergency, a dicarboxylic acid bis (polyoxyalkylene alkyl ether) ester, a dicarboxylic acid dialkoxyalkyl ester, and (eicosandioic acid / tetradecane) are used. It is preferably selected from the group consisting of (diacid) polyglyceryl-10. As the amphoteric ester, any one of dicarboxylic acid bis (polyoxyalkylene alkyl ether) ester, dicarboxylic acid dialkoxyalkyl ester, and (eicosandioic acid / tetradecanedioic acid) polyglyceryl-10 is used alone. Also, two or more kinds may be used in combination. Among these amphipathic esters, the dicarboxylic acid bis (polyoxyalkylene alkyl ether) ester is more preferable from the viewpoint of obtaining a better moisturizing feeling and detergency.
本発明に使用されるジカルボン酸ビス(ポリオキシアルキレンアルキルエーテル)エステルは、ジカルボン酸とポリオキシアルキレンアルキルエーテルとのジエステル化合物である。ジカルボン酸ビス(ポリオキシアルキレンアルキルエーテル)エステルのジエステル化合物を構成するジカルボン酸の具体例としては、例えば、シュウ酸、マロン酸、コハク酸、酒石酸、リンゴ酸、グルタル酸、アジピン酸、ペメリン酸、スベリン酸、アゼライン酸、セバシン酸、アスパラギン酸、グルタミン酸、アセトンジカルボン酸、フタル酸、シクロヘキサン−1,4−ジカルボン酸などが挙げられる。また、ジエステル化合物を構成するポリオキシアルキレンアルキルエーテルとしては、例えば、ポリオキシエチレンモノアルキルエーテルなどが挙げられ、より具体的には、例えば、ジエチレングリコールモノエチルエーテル、トリエチレングリコールモノエチルエーテルなどが挙げられる。 The dicarboxylic acid bis (polyoxyalkylene alkyl ether) ester used in the present invention is a diester compound of a dicarboxylic acid and a polyoxyalkylene alkyl ether. Specific examples of the dicarboxylic acid constituting the diester compound of the dicarboxylic acid bis (polyoxyalkylene alkyl ether) ester include, for example, oxalic acid, malonic acid, succinic acid, tartrate acid, malic acid, glutaric acid, adipic acid, pemeric acid, and the like. Examples thereof include suberic acid, azelaic acid, sebacic acid, aspartic acid, glutamic acid, acetonedicarboxylic acid, phthalic acid, cyclohexane-1,4-dicarboxylic acid and the like. Examples of the polyoxyalkylene alkyl ether constituting the diester compound include polyoxyethylene monoalkyl ether, and more specifically, diethylene glycol monoethyl ether and triethylene glycol monoethyl ether. Be done.
これらのジカルボン酸ビス(ポリオキシアルキレンアルキルエーテル)エステルの中でも、保湿感及び洗浄力をより良好に得る観点から、好ましくは、シクロヘキサン−1,4−ジカルボン酸とジエチレングリコールモノエチルエーテルとのジエステル化合物、具体的には、INCI名(International Cosmetic Ingredient Dictionary and Handbook,第13版,第1巻,CTFA,2010年,p.331):BIS−ETHOXYDIGLYCOL CYCLOHEXANE 1,4−DICARBOXYLATEで表記される、シクロへキサン−1,4−ジカルボン酸ビスエトキシジグリコールと称される化合物、及びコハク酸とジエチレングリコールモノエチルエーテルとのジエステル化合物、具体的には、INCI名(International Cosmetic Ingredient Dictionary and Handbook,第13版,第1巻,CTFA,2010年,p.331−332):BIS−ETHOXYDIGLYCOL SUCCINATEで表記される、コハク酸ビスエトキシジグリコールと称される化合物が挙げらる。 Among these dicarboxylic acid bis (polyoxyalkylene alkyl ether) esters, a diester compound of cyclohexane-1,4-dicarboxylic acid and diethylene glycol monoethyl ether is preferable from the viewpoint of obtaining a better moisturizing feeling and detergency. Specifically, INCI name (International Compound Industrial Compound Handbook, 13th edition, Volume 1, CTFA, 2010, p.331): BIS-ETHOXYDIGLYCOL CYCLOHEXANE 1,4-DICALBOX A compound called -1,4-dicarboxylic acid bisethoxydiglycol, and a diester compound of succinic acid and diethylene glycol monoethyl ether, specifically, INCI name (International Cosmetic Ingredient Dioldy and Handbook, 13th edition, 13th edition, Volume 1, CTFA, 2010, p.331-332): BIS-ETHOXYDIGLYCOL SUCCINE, a compound called bisethoxydiglycol succinate.
また、本発明において、前記シクロへキサン−1,4−ジカルボン酸ビスエトキシジグリコールの具体例としては、例えば、日本精化株式会社製の「Neosolue−Aqulio(商品名)」等が挙げられる。また、前記コハク酸ビスエトキシジグリコールの具体例としては、例えば、高級アルコール工業株式会社製の「ハイアクオスター DCS(商品名)」等が挙げられる。 Further, in the present invention, specific examples of the cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol include, for example, "Neosolue-Aquio (trade name)" manufactured by Nippon Fine Chemical Co., Ltd. Further, specific examples of the bisethoxydiglycol succinate include "High Aquos Star DCS (trade name)" manufactured by Higher Alcohol Industry Co., Ltd.
これらのジカルボン酸ビス(ポリオキシアルキレンアルキルエーテル)エステルは、1種単独で使用してもよく、また2種以上を組み合わせて使用してもよい。 These dicarboxylic acid bis (polyoxyalkylene alkyl ether) esters may be used alone or in combination of two or more.
本発明に使用されるジカルボン酸ジアルコキシアルキルエステルは、ジカルボン酸とアルコキシアルコールとのジエステル化合物である。ジカルボン酸ジアルコキシアルキルのジエステル化合物を構成するジカルボン酸の具体例としては、例えば、シュウ酸、マロン酸、コハク酸、酒石酸、リンゴ酸、グルタル酸、アジピン酸、ペメリン酸、スベリン酸、アゼライン酸、セバシン酸、アスパラギン酸、グルタミン酸、アセトンジカルボン酸、フタル酸、シクロヘキサン−1,4−ジカルボン酸などが挙げられる。また、ジエステル化合物を構成するアルコキシアルコールとしては、例えば、2−メトキシエタノール、2−エトキシエタノールなどが挙げられる。 The dicarboxylic acid dialkoxyalkyl ester used in the present invention is a diester compound of a dicarboxylic acid and an alkoxy alcohol. Specific examples of the dicarboxylic acid constituting the diester compound of the dicarboxylic acid dialkoxyalkyl include oxalic acid, malonic acid, succinic acid, tartaric acid, malic acid, glutaric acid, adipic acid, pemeric acid, suberic acid, and azelaic acid. Examples thereof include sebacic acid, aspartic acid, glutamic acid, acetonedicarboxylic acid, phthalic acid, cyclohexane-1,4-dicarboxylic acid and the like. Examples of the alkoxy alcohol constituting the diester compound include 2-methoxyethanol and 2-ethoxyethanol.
これらのジカルボン酸ジアルコキシアルキルエステル中でも、皮膚刺激低減性及び洗浄力をより良好に得る観点から、好ましくは、コハク酸と2−エトキシエタノールとのジエステル化合物、具体的には、コハク酸ジエトキシエチルが挙げられる。 Among these dicarboxylic acid dialkoxyalkyl esters, a diester compound of succinic acid and 2-ethoxyethanol is preferable, specifically, diethoxyethyl succinate, from the viewpoint of obtaining better skin irritation reduction property and detergency. Can be mentioned.
これらのジカルボン酸ジアルコキシアルキルエステル、1種単独で使用してもよく、また2種以上を組み合わせて使用してもよい。 These dicarboxylic acid dialkoxyalkyl esters may be used alone or in combination of two or more.
本発明に使用される(エイコサン二酸/テトラデカン二酸)ポリグリセリル−10としては、特に限定されないが、例えば、日本精化株式会社製の「Neosolue−Aqua(商品名)」、「Neosolue−AquaS(商品名)」等が挙げられる。 The polyglyceryl-10 (eicosanedioic acid / tetradecanedioic acid) used in the present invention is not particularly limited, but for example, "Neosolue-Aqua (trade name)" and "Neosolue-AquaS" manufactured by Nippon Seika Co., Ltd. Product name) ”and the like.
本発明の皮膚洗浄剤組成物における(B)成分の含有量としては特に限定されないが、例えば0.2重量%以上が挙げられる。保湿感及び洗浄力をより良好に得る観点から、(B)成分の含有量としては好ましくは0.4重量%以上が挙げられる。平滑感をより良好に得る観点から、(B)成分の含有量としてはより好ましくは0.5重量%以上が挙げられる。(B)成分の含有量の上記範囲の上限は特に限定されないが、皮膚洗浄料組成物の安定性等の観点から、例えば5重量%以下、好ましくは3重量%以下、より好ましくは2重量%以下、さらに好ましくは1重量%以下が挙げられる。 The content of the component (B) in the skin cleansing composition of the present invention is not particularly limited, and examples thereof include 0.2% by weight or more. From the viewpoint of obtaining a better moisturizing feeling and detergency, the content of the component (B) is preferably 0.4% by weight or more. From the viewpoint of obtaining a better smooth feeling, the content of the component (B) is more preferably 0.5% by weight or more. The upper limit of the content of the component (B) in the above range is not particularly limited, but from the viewpoint of stability of the skin cleansing composition, for example, 5% by weight or less, preferably 3% by weight or less, more preferably 2% by weight. Hereinafter, more preferably 1% by weight or less can be mentioned.
本発明の皮膚洗浄剤組成物において、(A)成分と(B)成分との比率は特に限定されず、上記の各含有量により定まるが、保湿感及び洗浄力をより良好に得る観点から、(A)成分1重量部に対して(B)成分が例えば0.01〜100重量部、好ましくは0.01〜10重量部、より好ましくは0.02〜5重量部、さらに好ましくは0.03〜1重量部、特に好ましくは0.03〜0.5重量部が挙げられる。 In the skin cleaning agent composition of the present invention, the ratio of the component (A) to the component (B) is not particularly limited and is determined by each of the above-mentioned contents, but from the viewpoint of obtaining a better moisturizing feeling and detergency. With respect to 1 part by weight of the component (A), the component (B) is, for example, 0.01 to 100 parts by weight, preferably 0.01 to 10 parts by weight, more preferably 0.02 to 5 parts by weight, still more preferably 0. 03-1 parts by weight, particularly preferably 0.03 to 0.5 parts by weight.
(C)セラミド類
本発明の皮膚洗浄料組成物は、(C)成分としてセラミド類を含有する。(C)成分を(A)成分及び(B)成分と組み合わせることにより、平滑感、保湿感及び柔軟感を総合的に向上させることができる。
(C) Ceramides The skin cleansing composition of the present invention contains ceramides as a component (C). By combining the component (C) with the component (A) and the component (B), the smoothness, moisturizing feeling and softness can be comprehensively improved.
セラミド類とは、セラミド、擬似セラミド、及び/又はグリコセラミドをいう。本発明においては、(C)成分として、セラミド、擬似セラミド、及びグリコセラミドのうちいずれか一種を使用してもよいし、複数種を組み合わせて使用してもよい。 Ceramides refer to ceramides, pseudo-ceramides, and / or glycoceramides. In the present invention, as the component (C), any one of ceramide, pseudo-ceramide, and glycoceramide may be used, or a plurality of types may be used in combination.
セラミドはスフィンゴ脂質の一種であり、スフィンゴシンのアミノ基に長鎖脂肪酸がアミド結合した化合物群の総称として公知の成分である。セラミドは、スフィンゴシンの構造(N−アシル基の構造など)及び長鎖脂肪酸の構造の違いにより、セラミド1、セラミド2、セラミド3、セラミド4、セラミド5、セラミド6I、セラミド6II、セラミド7、セラミド8、セラミド9、セラミド10等が挙げられる。これらのセラミドは、1種単独で使用してもよく、また2種以上を組み合わせて使用してもよい。これらのセラミドの中でも、好ましくはセラミド1、セラミド2、セラミド3が挙げられる。 Ceramide is a kind of sphingolipid, and is a known component as a general term for a group of compounds in which a long chain fatty acid is amide-bonded to an amino group of sphingosine. Ceramide is ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6I, ceramide 6II, ceramide 7, ceramide due to the difference in the structure of sphingosine (structure of N-acyl group, etc.) and the structure of long-chain fatty acid. 8, ceramide 9, ceramide 10, and the like can be mentioned. These ceramides may be used alone or in combination of two or more. Among these ceramides, ceramide 1, ceramide 2 and ceramide 3 are preferably mentioned.
本発明で使用されるセラミドの由来については、特に制限されず、セラミドの種類等に応じて適宜設定すればよく、例えば、動植物から抽出したもの、微生物醗酵法によって得られたもの、化学的に合成したもの等のいずれであってもよい。 The origin of the ceramide used in the present invention is not particularly limited and may be appropriately set according to the type of ceramide and the like. For example, those extracted from animals and plants, those obtained by a microbial fermentation method, and chemically It may be any of those synthesized.
擬似セラミドは、セラミドと構造及び性質が類似したセラミド類縁体であり、具体的には、下記一般式(I)で示される化合物、及び一般式(II)で示される化合物から選択される化合物が挙げられる。 Pseudo-ceramide is a ceramide analog having a structure and properties similar to those of ceramide. Specifically, a compound selected from the compound represented by the following general formula (I) and the compound represented by the general formula (II) is selected. Can be mentioned.
式(I)中、R11は炭素数10〜26の炭化水素基を表し、R12は炭素数9〜25の炭化水素基を表し、Xは−(CH2)n−を表し、nは2〜6の整数を表す。炭化水素基としては、好ましくはアルキル基又はアルケニル基が挙げられる。式(I)に示される擬似セラミドの具体例としては、N−(ヘキサデシロキシヒドロキシプロピル)−N−ヒドロキシエチルヘキサデカナミドが挙げられる。 In formula (I), R 11 represents a hydrocarbon group having 10 to 26 carbon atoms, R 12 represents a hydrocarbon group having 9 to 25 carbon atoms, X represents − (CH 2 ) n −, and n represents − (CH 2 ) n −. Represents an integer of 2-6. The hydrocarbon group preferably includes an alkyl group or an alkenyl group. Specific examples of the pseudo-ceramide represented by the formula (I) include N- (hexadecyloxyhydroxypropyl) -N-hydroxyethylhexadecanamid.
式(II)中、R21及びR22は同一又は異なっていてよい炭素数1〜40のヒドロキシル化されていてもよい炭化水素基を表し、R23は炭素数1〜6のアルキレン基又は単結合を表し、R24は水素原子、炭素数1〜12のアルコキシ基又は2,3−ジヒドロキシプロピルオキシ基を表す。但し、R23が単結合であるときはR24は水素原子である。炭化水素基としては、好ましくはアルキル基又はアルケニル基が挙げられる。 In formula (II), R 21 and R 22 represent hydrocarbon groups having 1 to 40 carbon atoms which may be the same or different and may be hydroxylated, and R 23 is an alkylene group having 1 to 6 carbon atoms or a single group. Representing a bond, R 24 represents a hydrogen atom, an alkoxy group having 1 to 12 carbon atoms or a 2,3-dihydroxypropyloxy group. However, when R 23 is a single bond, R 24 is a hydrogen atom. The hydrocarbon group preferably includes an alkyl group or an alkenyl group.
これらの擬似セラミドは、1種単独で使用してもよく、また2種以上を組み合わせて使用してもよい。 These pseudo-ceramides may be used alone or in combination of two or more.
グリコセラミドは、スフィンゴ糖脂質として公知の成分である。スフィンゴ糖脂質は、単糖又はオリゴ糖が結合したセラミドである。本発明で用いられるグリコセラミドとしては、好ましくは単糖が結合したセラミドが挙げられ、より好ましくはグルコシルセラミド(グルコースが結合したセラミド)及びガラクトシルセラミド(ガラクトースが結合したセラミド)が挙げられ、更に好ましくはグルコシルセラミドが挙げられる。 Glycoceramide is a component known as glycosphingolipid. Glycosphingolipids are ceramides to which monosaccharides or oligosaccharides are bound. Examples of the glycoceramide used in the present invention preferably include ceramide to which a monosaccharide is bound, more preferably glucosyl ceramide (ceramide to which glucose is bound) and galactosyl ceramide (ceramide to which galactose is bound), and further preferably. Can be mentioned as glucosylceramide.
また、グリコセラミドとしては、植物(例えば、コメヌカ、コムギ、コーン、コンニャク等の穀類;タモギタケ、マイタケ等の茸類等)、動物(例えば、哺乳動物の乳、牛脳等)、微生物(例えば、Aspergillus属、Rhizopus属、Monuscus属、Penicillium属に属する麹菌等)に由来するグリコセラミドが挙げられる。 Examples of glycoceramide include plants (for example, grains such as rice bran, wheat, corn, and konjak; mushrooms such as tamogitake and maitake), animals (for example, mammalian milk, cow brain, etc.), and microorganisms (for example, cow brain). Glycoseramides derived from Aspergillus, Rhizopus, Monuscus, Penicillium, etc.) can be mentioned.
本発明の皮膚洗浄剤組成物における(C)成分の含有量としては特に限定されないが、例えば0.005〜0.3重量%が挙げられる。(C)成分の上記範囲の下限としては、平滑感、保湿感及び/又は柔軟感をより良好に得る観点から、好ましくは0.01重量%以上が挙げられる。また、(C)成分の上記範囲の上限としては、製剤安定性の観点から、好ましくは0.2重量%以下、より好ましくは0.15重量%以下が挙げられる。 The content of the component (C) in the skin cleansing composition of the present invention is not particularly limited, and examples thereof include 0.005 to 0.3% by weight. The lower limit of the above range of the component (C) is preferably 0.01% by weight or more from the viewpoint of obtaining a smooth feeling, a moisturizing feeling and / or a soft feeling better. The upper limit of the above range of the component (C) is preferably 0.2% by weight or less, more preferably 0.15% by weight or less, from the viewpoint of formulation stability.
更に、(C)成分がグリコセラミドである場合、(C)成分の上記範囲の下限としては、平滑感、保湿感及び/又は柔軟感をより良好に得る観点から、より好ましくは0.05重量%以上が挙げられ、さらに好ましくは0.08重量%以上が挙げられる。 Further, when the component (C) is glycoceramide, the lower limit of the above range of the component (C) is more preferably 0.05 weight from the viewpoint of better obtaining a smooth feeling, a moisturizing feeling and / or a soft feeling. % Or more, more preferably 0.08% by weight or more.
本発明の皮膚洗浄剤組成物において、(A)成分と(C)成分との比率は特に限定されず、上記の各含有量により定まるが、保湿感及び/又は柔軟感とぬるつき抑制性とをより良好に得る観点から、(A)成分1重量部に対して(C)成分が例えば0.0005〜0.1重量部、好ましくは0.001〜0.01重量部が挙げられる。 In the skin cleansing composition of the present invention, the ratio of the component (A) to the component (C) is not particularly limited and is determined by each of the above-mentioned contents, but has a moisturizing feeling and / or a softness and a slimy inhibitory property. For example, 0.0005 to 0.1 parts by weight, preferably 0.001 to 0.01 parts by weight of the component (C) is mentioned with respect to 1 part by weight of the component (A).
(D)レシチン及び/又はリゾレシチン
本発明の皮膚洗浄料組成物は、(D)成分としてレシチン及び/又はリゾレシチンを含有していてもよい。(D)成分は、柔軟感を向上させる目的で、(A)成分、(B)成分及び(C)成分とともに共存させることができる。
(D) Lecithin and / or lysolecithin The skin cleansing composition of the present invention may contain lecithin and / or lysolecithin as a component (D). The component (D) can coexist with the component (A), the component (B) and the component (C) for the purpose of improving the softness.
本発明においては、(D)成分として、レシチン及びリゾレシチンの中から、レシチンを用いてもよいし、リゾレシチンを用いてもよいし、レシチンとリゾレシチンとを組み合わせて用いてもよい。 In the present invention, as the component (D), lecithin may be used, lysolecithin may be used, or lecithin and lysolecithin may be used in combination from among lecithin and lysolecithin.
レシチンは、ホスファチジルコリン、ホスファチジルエタノールアミン、ホスファチジルセリン、ホスファチジルイノシトールなどのリン脂質と、トリグリセリド、脂肪酸、植物油からの炭水化物などの成分との混合物であり、医薬品、医薬部外品、化粧品において公知の成分である。 Lecithin is a mixture of phospholipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, and phosphatidylinositol with components such as triglycerides, fatty acids, and carbohydrates from vegetable oils, and is a known component in pharmaceuticals, quasi-drugs, and cosmetics. is there.
本発明に使用されるレシチンとしては、動植物由来の天然レシチン(例えば、大豆レシチン、卵黄レシチン等)そのものであってもよいし、天然レシチンの化学処理物であってもよいし、天然レシチンの精製物であってもよい。天然レシチンの化学処理物としては、水素添加処理により得られた水素添加レシチン(例えば、完全水素添加レシチンや部分水素添加レシチン)、水酸化処理により得られた水酸化レシチン等が挙げられる。天然レシチンの精製物としては、アセトン等の溶剤によりホスファチジルコリンの含有量を高めたレシチンが挙げられる。 The lecithin used in the present invention may be natural lecithin derived from animals and plants (for example, soybean lecithin, egg yolk lecithin, etc.) itself, a chemically treated product of natural lecithin, or purification of natural lecithin. It may be a thing. Examples of the chemically treated product of natural lecithin include hydrogenated lecithin obtained by hydrogenation treatment (for example, fully hydrogenated lecithin and partially hydrogenated lecithin), hydroxylated lecithin obtained by hydroxylation treatment, and the like. Examples of the purified product of natural lecithin include lecithin in which the content of phosphatidylcholine is increased by a solvent such as acetone.
本発明に使用されるリゾレシチンとしては、上記のレシチン(天然レシチン、天然レシチンの化学処理物、天然レシチンの精製物)のリゾ体が挙げられる。リゾレシチンは、レシチンをホスホリパーゼA2などの酵素による加水分解(溶解)でホスファチジルコリンの2位の脂肪酸が除去された構造を有する。 Examples of the lysolecithin used in the present invention include lyso-forms of the above-mentioned lecithin (natural lecithin, chemically treated product of natural lecithin, purified product of natural lecithin). Lysolecithin has a structure in which the fatty acid at the 2-position of phosphatidylcholine is removed by hydrolysis (dissolution) of lecithin by an enzyme such as phospholipase A2.
これらのレシチン及び/又はリゾレシチンは、1種単独で使用してもよく、また2種以上を組み合わせて使用してもよい。 These lecithin and / or lysolecithin may be used alone or in combination of two or more.
本発明の皮膚洗浄剤組成物における(D)成分の含有量としては特に限定されないが、柔軟感をより良好に得る観点から、例えば0.005〜3重量%、好ましくは0.01〜1重量%、より好ましくは0.01〜0.5重量%が挙げられる。 The content of the component (D) in the skin cleansing composition of the present invention is not particularly limited, but from the viewpoint of obtaining a better softness, for example, 0.005 to 3% by weight, preferably 0.01 to 1% by weight. %, More preferably 0.01 to 0.5% by weight.
本発明の皮膚洗浄剤組成物において、(A)成分と(D)成分との比率は特に限定されず、上記の各含有量により定まるが、保湿感及び/又は柔軟感をより良好に得る観点から、(A)成分1重量部に対して(D)成分が例えば0.002〜0.3重量部、好ましくは0.004〜0.25重量部が挙げられる。 In the skin cleansing composition of the present invention, the ratio of the component (A) to the component (D) is not particularly limited and is determined by each of the above contents, but from the viewpoint of obtaining a better moisturizing feeling and / or a soft feeling. Therefore, the component (D) is, for example, 0.002 to 0.3 parts by weight, preferably 0.004 to 0.25 parts by weight, based on 1 part by weight of the component (A).
他の成分
本発明の皮膚洗浄剤組成物には、前記成分の他に、本発明の効果を損なわない範囲で、製剤化等に必要とされる他の基剤や添加剤が含まれていてもよい。このような添加剤については、薬学的に許容されることを限度として特に制限されないが、例えば、水、炭素数1〜5の低級アルコール(エタノール、イソプロパノール等)、及び多価アルコール(エチレングリコール、1,3−ブチレングリコール(1,3−BG)、プロピレングリコール、イソプレングリコール、ジエチレングリコール、ジプロピレングリコール、ポリプロピレングリコール、グリセリン等)等の水性基剤;カチオン性界面活性剤、アニオン性界面活性剤、両イオン性界面活性剤等の界面活性剤(上記(A)成分及び(D)成分以外);防腐剤(メチルパラベン、プロピルパラベン、安息香酸、安息香酸ナトリウム、ソルビン酸等)、着香剤(シトラール、1,8−シネオール、シトロネラール、ファルネソール等)、着色剤(タール色素(褐色201号、青色201号、黄色4号、黄色403号等)、カカオ色素、クロロフィル、酸化アルミニウム等)、粘稠剤(カルボキシビニルポリマー、ヒプロメロース、ポリビニルピロリドン、アルギン酸ナトリウム、エチルセルロース、カルボキシメチルセルロースナトリウム、キサンタンガム、カラギーナン等)、pH調整剤(リン酸、塩酸、クエン酸、クエン酸ナトリウム、コハク酸、酒石酸、水酸化ナトリウム、水酸化カリウム、トリエタノールアミン、トリイソプロパノールアミン等)、湿潤剤(dl−ピロリドンカルボン酸ナトリウム液、D−ソルビトール液、マクロゴール等)、安定化剤(ジブチルヒドロキシトルエン、ブチルヒドロキシアニソール、エデト酸ナトリウム、メタリン酸ナトリウム、L−アルギニン、L−アスパラギン酸、DL−アラニン、グリシン、エリソルビン酸ナトリウム、没食子酸プロピル、亜硫酸ナトリウム、二酸化硫黄、クロロゲン酸、カテキン、ローズマリー抽出物等)、酸化防止剤、紫外線吸収剤、キレート剤、粘着剤、緩衝剤、溶解補助剤、可溶化剤、保存剤等の添加剤が挙げられる。これらの基材や添加剤は、1種単独で使用してもよく、また2種以上を組み合わせて使用してもよい。これらの基材や添加剤の含有量は、製剤形態等に応じて適宜設定することができる。
Other Ingredients In addition to the above ingredients, the skin cleansing composition of the present invention contains other bases and additives required for formulation and the like as long as the effects of the present invention are not impaired. May be good. Such additives are not particularly limited as long as they are pharmaceutically acceptable, but for example, water, lower alcohols having 1 to 5 carbon atoms (ethanol, isopropanol, etc.), and polyhydric alcohols (ethylene glycol, Aqueous bases such as 1,3-butylene glycol (1,3-BG), propylene glycol, isopropanol, diethylene glycol, dipropylene glycol, polypropylene glycol, glycerin, etc.; cationic surfactants, anionic surfactants, Surfactants such as amphoteric surfactants (other than the above components (A) and (D)); preservatives (methylparaben, propylparaben, benzoic acid, sodium benzoate, sorbic acid, etc.), flavoring agents (citral) , 1,8-Cineol, citroneral, farnesol, etc.), colorants (tar pigments (brown 201, blue 201, yellow 4, yellow 403, etc.), cacao pigments, chlorophyll, aluminum oxide, etc.), viscous agents (Carboxyvinyl polymer, hypromellose, polyvinylpyrrolidone, sodium alginate, ethyl cellulose, sodium carboxymethyl cellulose, xanthan gum, carrageenan, etc.), pH adjuster (phosphate, hydrochloric acid, citric acid, sodium citrate, succinic acid, tartrate acid, sodium hydroxide, etc. Potassium hydroxide, triethanolamine, triisopropanolamine, etc.), wetting agent (dol-pyrrolidone sodium carboxylate solution, D-sorbitol solution, macrogol, etc.), stabilizer (dibutylhydroxytoluene, butylhydroxyanisole, sodium edetate, etc.) , Sodium metaphosphate, L-arginine, L-aspalanoic acid, DL-alanine, glycine, sodium erythorbinate, propyl gallate, sodium sulfite, sulfur dioxide, chlorogenic acid, catechin, rosemary extract, etc.), antioxidants, Examples thereof include additives such as an ultraviolet absorber, a chelating agent, an adhesive, a buffer, a solubilizing agent, a solubilizing agent, and a preservative. These base materials and additives may be used alone or in combination of two or more. The contents of these base materials and additives can be appropriately set according to the formulation form and the like.
本発明の皮膚洗浄剤組成物には、前記成分の他に、本発明の効果を損なわない範囲で、必要に応じて他の薬理成分を含有していてもよい。このような薬理成分としては、例えば、ビタミン類(ビタミンA類、ビタミンB1類、ビタミンB2類、ビタミンB5類、ビタミンB6類、ビタミンB12類、ビタミンC類、ビタミンD類、ビタミンK類、ナイアシン類、葉酸、ビオチン、リコペン等)、抗ヒスタミン剤(ジフェンヒドラミン、塩酸ジフェンヒドラミン等)、局所麻酔剤(プロカイン、テトラカイン、ブピパカイン、メピパカイン、クロロプロカイン、プロパラカイン、メプリルカイン又はこれらの塩、オルソカイン、オキセサゼイン、オキシポリエントキシデカン、ロートエキス、ペルカミンパーゼ、テシットデシチン等)、抗炎症剤(インドメタシン、フェルビナク、ジクロフェナクナトリウム、ロキソプロフェンナトリウム等)、皮膚保護剤(コロジオン、ヒマシ油等)、血行促進成分(ノニル酸ワニリルアミド、ニコチン酸ベンジルエステル、カプサイシン、トウガラシエキス等)、清涼化剤(メントール、カンフル、ボルネオール、ハッカ水、ハッカ油等)、ムコ多糖類(コンドロイチン硫酸ナトリウム、グルコサミン等)等が挙げられる。これらの薬理成分は、1種単独で使用してもよく、また2種以上を組み合わせて使用してもよい。これらの薬理成分を含有させる場合、その含有量については、使用する薬理成分の種類、期待する効果等に応じて適宜設定すればよい。 In addition to the above-mentioned components, the skin cleansing composition of the present invention may contain other pharmacological components, if necessary, as long as the effects of the present invention are not impaired. Examples of such pharmacological components include vitamins (vitamin A, vitamin B1, vitamin B2, vitamin B5, vitamin B6, vitamin B12, vitamin C, vitamin D, vitamin K, niacin). Kinds, folic acid, biotin, lycopene, etc.), antihistamines (diphenhydramine, diphenhydramine hydrochloride, etc.), local anesthetics (procaine, tetrakine, bupipacain, mepipacine, chloroprocine, proparakine, meprilcaine or salts thereof, orthokine, oxesazein, oxypolyentoxy Decane, funnel extract, percamine pase, tesitdecitin, etc.), anti-inflammatory agents (indomethasin, fervinac, diclofenac sodium, loxoprofen sodium, etc.), skin protectants (corodione, sunflower oil, etc.) , Capsaicin, Togarashi extract, etc.), refreshing agents (menthol, camphor, borneol, peppermint water, peppermint oil, etc.), mucopolysaccharides (sodium chondroitin sulfate, glucosamine, etc.) and the like. These pharmacological components may be used alone or in combination of two or more. When these pharmacological components are contained, the content thereof may be appropriately set according to the type of the pharmacological component used, the expected effect, and the like.
形態
本発明の皮膚洗浄剤組成物の形態については特に制限されず、液状、クリーム状、ゲル状等が挙げられるが、好ましくは常温で液状である。また、本発明の皮膚洗浄剤組成物は、液状の皮膚洗浄剤組成物がコットンや不織布等のシート基材に含浸させられた形態であってもよい。
Form The form of the skin cleansing composition of the present invention is not particularly limited and may be liquid, creamy, gel or the like, but is preferably liquid at room temperature. Further, the skin cleansing composition of the present invention may be in the form of a liquid skin cleansing composition impregnated in a sheet base material such as cotton or a non-woven fabric.
容器
本発明の皮膚洗浄剤組成物を収容する容器については、特に制限されず、形態や用途等に応じて適宜選択すればよいが、例えば、噴霧式容器、注下又は滴下式容器(特に洗浄瓶)、ポンプ式容器、チューブ式容器、包装袋、箱状容器等が挙げられる。特に、本発明の皮膚洗浄剤組成物が液状である場合、容器としては、噴霧式容器、注下又は滴下式容器(特に洗浄瓶)、ポンプ式容器、及びポンプフォーマー容器が挙げられる。また、本発明の皮膚洗浄剤組成物がシート基材に含浸させられた形態である場合は、容器としては、包装袋、箱状容器が挙げられる。
Container The container for accommodating the skin cleaning agent composition of the present invention is not particularly limited and may be appropriately selected depending on the form, application and the like. For example, a spray type container, a pouring or dropping type container (particularly cleaning). Bottles), pump-type containers, tube-type containers, packaging bags, box-shaped containers, and the like. In particular, when the skin cleansing composition of the present invention is in a liquid state, examples of the container include a spray type container, a pouring or dropping type container (particularly a washing bottle), a pump type container, and a pump former container. When the skin cleansing composition of the present invention is impregnated in a sheet base material, examples of the container include a packaging bag and a box-shaped container.
本発明においては、これらの容器の中でも、肌への塗布の手軽さ及び塗布時における手等による物理摩擦を回避する観点から、特に好ましくは噴霧式容器が挙げられる。噴霧式容器としては、非エアゾール式スプレー容器であるポンプ式スプレー容器、及び、エアゾール式スプレー容器が挙げられる。噴霧式容器の口径(ノズル内径)としては、例えば0.01〜3mmφ、好ましくは0.1〜1mmφが挙げられる。噴霧式容器がポンプ式スプレー容器である場合の1プッシュあたりの噴射量としては、例えば0.05〜1.2g、好ましくは0.1〜0.3gが挙げられる。 In the present invention, among these containers, a spray-type container is particularly preferable from the viewpoint of easy application to the skin and avoiding physical friction by hand or the like at the time of application. Examples of the spray type container include a pump type spray container which is a non-aerosol type spray container and an aerosol type spray container. Examples of the diameter (nozzle inner diameter) of the spray container include 0.01 to 3 mmφ, preferably 0.1 to 1 mmφ. When the spray type container is a pump type spray container, the injection amount per push is, for example, 0.05 to 1.2 g, preferably 0.1 to 0.3 g.
用途
本発明の皮膚洗浄剤組成物は、洗浄のために皮膚に適用するものであれば特に限定されない。本発明の皮膚洗浄剤組成物が洗い上がりの皮膚におけるつるつるとした平滑感、しっとりとした保湿感、及びふっくらとした柔軟感に優れているため、皮膚に適用された後に洗い流す使用態様、より具体的には、皮膚の油脂、汗などの体液や汚れ等を除去するために用いられる皮膚洗浄料、及び化粧を落とすために用いられるクレンジング等、特に好ましくは上記皮膚洗浄料としての用途において好適である。
Applications The skin cleansing composition of the present invention is not particularly limited as long as it is applied to the skin for cleaning. Since the skin cleansing composition of the present invention is excellent in smooth smoothness, moisturizing feeling, and fluffy softness on the washed skin, the usage mode of washing off after being applied to the skin, more specifically. Specifically, it is particularly suitable for use as the above-mentioned skin cleaning agent, such as a skin cleaning agent used for removing body fluids and stains such as oil and sweat on the skin, and cleansing used for removing makeup. is there.
本発明の皮膚洗浄剤組成物は、水で薄めて泡立てて皮膚に塗布してもよいし、水で薄めることなく、泡立てずにそのまま皮膚に塗布することで使用してもよい。水で薄めることなく、泡立てずにそのまま皮膚に塗布することで使用する場合、1回当たりの使用量としては、界面活性剤の濃度及び汚れの程度等にもよるが、例えば洗顔に用いる場合0.5〜3g、好ましくは1〜2gが挙げられる。 The skin cleansing composition of the present invention may be diluted with water and foamed to be applied to the skin, or may be used by being applied to the skin as it is without foaming without being diluted with water. When used by applying it to the skin as it is without foaming without diluting with water, the amount used at one time depends on the concentration of the surfactant and the degree of dirt, but for example, when used for face washing 0 .5 to 3 g, preferably 1 to 2 g.
具体的な使用態様として、本発明の皮膚洗浄剤組成物が注下又は滴下式容器(特に洗浄瓶)、ポンプ式容器、チューブ式容器等に収容されている場合は、皮膚洗浄剤組成物を容器からいったん手に取り、手で洗浄対象部位に塗布することができる。また、本発明の皮膚洗浄剤組成物がシート基材に含浸させられている場合は、シート基材を手に取り、洗浄対象部位にあてがうことで塗布することができる。 As a specific mode of use, when the skin cleansing composition of the present invention is contained in a pouring or dropping type container (particularly a washing bottle), a pump type container, a tube type container, etc., the skin cleansing agent composition is used. It can be picked up from the container and applied to the area to be cleaned by hand. When the skin cleansing composition of the present invention is impregnated in the sheet base material, it can be applied by picking up the sheet base material and applying it to the site to be cleaned.
特に好ましい使用態様として、噴霧式容器、注下又は滴下式容器(特に洗浄瓶)、好ましくは噴霧式容器に収容された皮膚洗浄剤組成物を、手に取ることなく、直接的に洗浄対象部位に塗布することができる。このように、皮膚洗浄剤組成物を直接的に洗浄対象部位に塗布する場合、洗浄対象部位の皮膚と手との間に生じる摩擦や、洗浄部位の皮膚と気泡と間に生じる摩擦といった物理的摩擦を一切与えることなく、液流の機械力を利用するだけで洗浄することが可能になる。本発明の皮膚洗浄剤組成物は、低刺激且つ洗浄力に優れた処方であるため、このように物理的摩擦を与えずに液流の機械力を利用して洗浄することで、洗浄時における肌への負担が顕著に軽減され極めて優しい洗浄方法が可能となる。なお、本発明の皮膚洗浄剤組成物は、前述のような肌に物理的摩擦を与えない洗浄方法に特に適しているが、皮膚洗浄剤組成物を洗浄対象部位に塗布した後に手等を用いてこすり洗いする使用方法を除外するものではない。 As a particularly preferable usage mode, a spray-type container, a pouring or dropping-type container (particularly a washing bottle), and preferably a skin cleansing agent composition contained in the spray-type container can be directly cleaned without picking it up. Can be applied to. In this way, when the skin cleansing agent composition is applied directly to the cleansing site, physical friction such as friction generated between the skin and hands of the cleansing site and friction generated between the skin and air bubbles of the cleansing site. It is possible to wash by using the mechanical force of the liquid flow without giving any friction. Since the skin cleansing composition of the present invention is a formulation that is mild and has excellent cleansing power, it is possible to wash the skin by using the mechanical force of the liquid flow without giving physical friction in this way. The burden on the skin is remarkably reduced, and an extremely gentle cleaning method becomes possible. The skin cleansing composition of the present invention is particularly suitable for the above-mentioned cleaning method that does not give physical friction to the skin, but after applying the skin cleansing composition to the site to be cleaned, a hand or the like is used. It does not exclude the usage of scrubbing.
本発明の皮膚洗浄剤組成物の洗浄対象部位としては、あらゆる身体部位の洗浄が可能であるため特に制限されず、例えば、手、髪、頭皮、体、顔等が挙げられる。特に、本発明の皮膚洗浄剤組成物が洗い上がりの皮膚における平滑感、保湿感、及び柔軟感に優れているため、これらの使用感を特に感じやすい顔への使用において好適である。 The site to be cleaned of the skin cleansing composition of the present invention is not particularly limited because it can clean any body part, and examples thereof include hands, hair, scalp, body, and face. In particular, since the skin cleansing composition of the present invention is excellent in smoothness, moisturizing feeling, and softness feeling on the washed skin, it is suitable for use on the face where these feelings of use are particularly easy to feel.
洗浄後、皮膚洗浄剤組成物は、水で洗い流すことができる。水で洗い流す場合は、通常の洗顔と同様に行えばよいが、肌への負担を軽減させる観点からは、手による摩擦を与えないように水流の機械力を利用して洗い流すことが好ましい。 After washing, the skin cleansing composition can be rinsed with water. When rinsing with water, it may be performed in the same manner as a normal face wash, but from the viewpoint of reducing the burden on the skin, it is preferable to wash off using the mechanical force of the water stream so as not to give friction by hand.
製造方法
本発明の皮膚洗浄剤組成物は、前述する(A)〜(C)成分、及び必要に応じて配合される(D)成分、並びに必要に応じて配合される他の成分等を混合して、所定の形態に調製することによって製造される。
Production Method The skin cleansing composition of the present invention is a mixture of the above-mentioned components (A) to (C), the component (D) to be blended as needed, and other components to be blended as needed. Then, it is produced by preparing it into a predetermined form.
以下に実施例を示して本発明をより具体的に説明するが、本発明はこれらに限定されるものではない。 The present invention will be described in more detail with reference to Examples below, but the present invention is not limited thereto.
表1〜2に示す組成の皮膚洗浄剤組成物を調製した。表1〜2に示す各成分の詳細は以下の通りである。調製した皮膚洗浄剤組成物を以下の評価試験に供した。 A skin cleansing composition having the composition shown in Tables 1 and 2 was prepared. Details of each component shown in Tables 1 and 2 are as follows. The prepared skin cleansing composition was subjected to the following evaluation test.
(A)アミノ酸系界面活性剤
・ココイルメチルタウリンNa(日油株式会社製「ダイヤポンK−SF(商品名)」)
・コカミドプロピルベタイン(川研ファインケミカル株式会社製「ソフタゾリンCPB(商品名)」)
・ココイルグルタミン酸TEA(味の素株式会社製 「アミソフトCT−12S(商品名)」)
・ココイルメチルタウリンナトリウム(日光ケミカルズ株式会社製「NIKKOL CMT−30(商品名)」)
・N−ラウロイル−N−メチル−β−アラニンナトリウム(日油株式会社製「ソフティルトAS−L(商品名)」)
・N−ラウロイルアスパラギン酸ナトリウム(旭化成ファインケミカル株式会社製「アミノフォーマー FLDS−L(商品名)」)
・ココイルメチルアラニンナトリウム(川研ファインケミカル株式会社製「アラノンACE(商品名)」)
・コカミドプロピルベタイン(日光ケミカルズ製「NIKKOL AM−3130N(商品名)」)
(a)その他の界面活性剤
・ラウリル硫酸ナトリウム(花王株式会社製「エマール 0(商品名)」
・ラウリン酸ナトリウム(日油株式会社製「ノンサールLN−1(商品名)」
・コカミドDEA(川研ファインケミカル株式会社製「アミゾールCDE−G(商品名)」)
・ポリオキシエチレンラウリルエーテル酢酸ナトリウム(花王株式会社製「カオーアキポ RLM−100NV(商品名)」)
・モノステアリン酸ポリオキシエチレンソルビタン(花王株式会社製 レオドールTW−S120V(商品名))
・グリセリンモノー2−エチルヘキシルエーテル液(SEPPIC社製「sensiva SC 50 JP(商品名)」)
・PEG−60水添ヒマシ油(ポリオキシエチレン硬化ヒマシ油;日光ケミカルズ株式会社製 「NIKKOL HCO−60(商品名)」)
(B)両親媒性エステル
・シクロヘキサン−1,4−ジカルボン酸ビスエトキシジグリコール(日本精化株式会社製「Neosolue−Aqulio(商品名)」)
・コハク酸ビスエトキシジグリコール(高級アルコール工業株式会社製「ハイアクオスター DCS(商品名)」)
(C)セラミド類
・セラミド2(高砂香料工業株式会社製「Ceramide TIC−001(商品名)」)
・グルコシルセラミド(一丸ファルコス株式会社製「水溶性セラミドRC(商品名)」)
(D)レシチン及び/又はリゾレシチン
・リゾレシチン(協和発酵バイオ株式会社製「リゾレシチン協和(商品名)」)
・レシチン(日清オイリオグループ株式会社製「ベイシス LP−20(商品名)」)
(A) Amino acid-based surfactant, cocoyl methyl taurine Na (NOF CORPORATION "Diapon K-SF (trade name)")
・ Cocamidopropyl Betaine (“Softazoline CPB (trade name)” manufactured by Kawaken Fine Chemicals Co., Ltd.)
・ Cocoyl glutamic acid TEA (Ajinomoto Co., Inc. "Amisoft CT-12S (trade name)")
・ Sodium cocoyl methyl taurine (“NIKKOL CMT-30 (trade name)” manufactured by Nikko Chemicals Co., Ltd.)
-N-lauroyl-N-methyl-β-alanine sodium (NOF CORPORATION "Softilt AS-L (trade name)")
・ Sodium N-lauroyl aspartate (“Aminoformer FLDS-L (trade name)” manufactured by Asahi Kasei Fine Chemicals Co., Ltd.)
・ Cocoyl methylalanine sodium ("Alanon ACE (trade name)" manufactured by Kawaken Fine Chemicals Co., Ltd.)
・ Cocamidopropyl betaine (Nikko Chemicals "NIKKOL AM-3130N (trade name)")
(A) Other surfactants-Sodium lauryl sulfate (Kao Corporation "Emar 0 (trade name)"
・ Sodium laurate (NOF CORPORATION "Nonsar LN-1 (trade name)"
・ Cocamide DEA ("Amisol CDE-G (trade name)" manufactured by Kawaken Fine Chemicals Co., Ltd.)
-Polyoxyethylene lauryl ether sodium acetate (Kao Corporation "Kao Akipo RLM-100NV (trade name)")
-Polyoxyethylene sorbitan monostearate (Kao Corporation Leodor TW-S120V (trade name))
-Glycerin mono-2-ethylhexyl ether solution ("Sensiva SC 50 JP (trade name)" manufactured by SEPPIC)
-PEG-60 hydrogenated castor oil (polyoxyethylene hydrogenated castor oil; "NIKKOL HCO-60 (trade name)" manufactured by Nikko Chemicals Co., Ltd.)
(B) Amphiphilic ester cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol (Nippon Fine Chemical Co., Ltd. "Neosolue-Aquolio (trade name)")
・ Bisethoxydiglycol succinate (“High Aquos Star DCS (trade name)” manufactured by Higher Alcohol Industry Co., Ltd.)
(C) Ceramides / Ceramide 2 ("Ceramide TIC-001 (trade name)" manufactured by Takasago International Corporation)
・ Glucosyl ceramide (“Water-soluble ceramide RC (trade name)” manufactured by Ichimaru Falcos Co., Ltd.)
(D) Lecithin and / or lysolecithin / lysolecithin ("Resolecithin Kyowa (trade name)" manufactured by Kyowa Hakko Bio Co., Ltd.)
・ Lecithin (“Basis LP-20 (trade name)” manufactured by Nisshin Oillio Group Co., Ltd.)
<つるつる感(平滑感)評価>
調製した皮膚洗浄剤組成物について、化粧品評価専門パネラー10名が洗いあがり時のつるつる感の評価を行った。具体的には、表1の各皮膚洗浄剤組成物についてはポンプ式スプレー容器(竹本容器株式会社製「Z−155−C110(商品名)」(1プッシュあたりの噴射量は0.15g)に収容し、1.5gを顔に直接的に噴霧することで塗布した。5秒程度放置し、その後、水で洗い流した。また、表2の各皮膚洗浄剤組成物についてはポンプフォーマー容器に収容し、1.5gを顔に塗布した。5秒程度擦り洗いを行い、その後、水で洗い流した。洗い流し後、水を拭き取らずに、肌のつるつる感(平滑感)を以下の指標に基づいて評価した。
5点:つるつる感(平滑感)が十分ある
4点:つるつる感(平滑感)がある
3点:つるつる感(平滑感)がややある
2点:つるつる感(平滑感)があまりない
1点:つるつる感(平滑感)が全くない
<Smoothness (smoothness) evaluation>
With respect to the prepared skin cleansing composition, 10 panelists specializing in cosmetics evaluation evaluated the smooth feeling at the time of washing. Specifically, for each skin cleansing composition in Table 1, a pump-type spray container (“Z-155-C110 (trade name)” manufactured by Takemoto Yohki Co., Ltd. (injection amount per push is 0.15 g)). It was contained and applied by spraying 1.5 g directly onto the face. It was left for about 5 seconds and then rinsed with water. In addition, each skin cleansing composition in Table 2 was placed in a pump former container. It was contained and 1.5 g was applied to the face. It was rubbed for about 5 seconds and then rinsed with water. After rinsing, the smoothness (smoothness) of the skin was used as the following index without wiping off the water. Evaluated based on.
5 points: Sufficient smoothness (smoothness) 4 points: Smoothness (smoothness) 3 points: Slightly smoothness (smoothness) 2 points: Not very smooth (smoothness) 1 point: There is no slippery feeling (smoothness)
パネラー10名の獲得スコアを合計し、以下の分類によりぬるつき感抑制性の程度を評価した。結果を表1〜4に示す。
◎:40点以上
○:31点以上40点未満
△:22点以上33点未満
×:22点未満
The scores obtained by the 10 panelists were totaled, and the degree of slimy feeling suppression was evaluated by the following classification. The results are shown in Tables 1 to 4.
◎: 40 points or more
◯: 31 points or more and less than 40 points
Δ: 22 points or more and less than 33 points
×: Less than 22 points
<しっとり感(保湿感)評価>
調製した皮膚洗浄剤組成物について、化粧品評価専門パネラー10名が洗いあがり時のしっとり感(保湿感)の評価を行った。具体的には、表1の各皮膚洗浄剤組成物についてはポンプ式スプレー容器(竹本容器株式会社製「Z−155−C110(商品名)」(1プッシュあたりの噴射量は0.15g)に収容し、1.5gを顔に直接的に噴霧することで塗布した。5秒程度放置し、その後、水で洗い流した。また、表2の各皮膚洗浄剤組成物についてはポンプフォーマー容器に収容し、1.5gを顔に塗布した。5秒程度擦り洗いを行い、その後、水で洗い流した。タオルで顔を抑えて水を吸い取った後、しっとり感(保湿感)を以下の指標に基づいて官能評価することで採点した。
5点:しっとり感(保湿感)が十分ある
4点:しっとり感(保湿感)がある
3点:しっとり感(保湿感)がややある
2点:しっとり感(保湿感)があまりない
1点:しっとり感(保湿感)が全くない
<Evaluation of moisturizing feeling>
Ten panelists specializing in cosmetics evaluation evaluated the moisturizing feeling (moisturizing feeling) of the prepared skin cleansing composition after washing. Specifically, for each skin cleansing composition in Table 1, a pump-type spray container (“Z-155-C110 (trade name)” manufactured by Takemoto Yohki Co., Ltd. (injection amount per push is 0.15 g)). It was contained and applied by spraying 1.5 g directly onto the face. It was left for about 5 seconds and then rinsed with water. In addition, each skin cleansing composition in Table 2 was placed in a pump former container. After accommodating, 1.5 g was applied to the face. After scrubbing for about 5 seconds and then rinsing with water. After holding the face with a towel and absorbing water, the moist feeling (moisturizing feeling) was used as the following index. Scored by sensory evaluation based on.
5 points: Sufficient moisturizing feeling (moisturizing feeling) 4 points: Moisturizing feeling (moisturizing feeling) 3 points: Moisturizing feeling (moisturizing feeling) slightly 2 points: Moisturizing feeling (moisturizing feeling) not so much 1 point: No moisturizing feeling (moisturizing feeling)
パネラー10名の獲得スコアを合計し、以下の分類によりしっとり感(保湿感)の程度を評価した。結果を表1〜4に示す。
◎:40点以上
○:28点以上40点未満
△:25点以上28点未満
×:25点未満
The scores obtained by the 10 panelists were totaled, and the degree of moisturizing feeling (moisturizing feeling) was evaluated according to the following classification. The results are shown in Tables 1 to 4.
◎: 40 points or more
◯: 28 points or more and less than 40 points
Δ: 25 points or more and less than 28 points
×: Less than 25 points
<ふっくら感(柔軟感)評価>
調製した皮膚洗浄剤組成物について、化粧品評価専門パネラー10名が洗いあがり時のふっくら感(柔軟感)の評価を行った。具体的には、表1の各皮膚洗浄剤組成物についてはポンプ式スプレー容器(竹本容器株式会社製「Z−155−C110(商品名)」(1プッシュあたりの噴射量は0.15g)に収容し、1.5gを顔に直接的に噴霧することで塗布した。5秒程度放置し、その後、水で洗い流した。また、表2の各皮膚洗浄剤組成物についてはポンプフォーマー容器に収容し、1.5gを顔に塗布した。5秒程度擦り洗いを行い、その後、水で洗い流した。タオルで顔を抑えて水を吸い取った後、ふっくら感(柔軟感)を以下の指標に基づいて官能評価することで採点した。
5点:ふっくら感(柔軟感)が十分ある
4点:ふっくら感(柔軟感)がある
3点:ふっくら感(柔軟感)がややある
2点:ふっくら感(柔軟感)があまりない
1点:ふっくら感(柔軟感)が全くない
<Plump feeling (flexibility) evaluation>
About the prepared skin cleansing composition, 10 panelists specializing in cosmetics evaluation evaluated the fluffy feeling (softness) at the time of washing. Specifically, for each skin cleansing composition in Table 1, a pump-type spray container (“Z-155-C110 (trade name)” manufactured by Takemoto Yohki Co., Ltd. (injection amount per push is 0.15 g)). It was contained and applied by spraying 1.5 g directly onto the face. It was left for about 5 seconds and then rinsed with water. In addition, each skin cleansing composition in Table 2 was placed in a pump former container. It was contained and 1.5 g was applied to the face. It was scrubbed for about 5 seconds and then rinsed with water. After holding the face with a towel and absorbing the water, the fluffy feeling (flexibility) was used as the following index. Scored by sensory evaluation based on.
5 points: Sufficient fluffy feeling (flexible feeling) 4 points: Puffy feeling (flexible feeling) 3 points: Slightly fluffy feeling (flexible feeling) 2 points: Not much fluffy feeling (flexible feeling) 1 point: There is no feeling of plumpness (flexibility)
パネラー10名の獲得スコアを合計し、以下の分類によりぬるつき感抑制性の程度を評価した。結果を表1〜4に示す。
◎:40点以上
○:34点以上40点未満
△:23点以上34点未満
×:23点未満
The scores obtained by the 10 panelists were totaled, and the degree of slimy feeling suppression was evaluated by the following classification. The results are shown in Tables 1 to 4.
◎: 40 points or more
◯: 34 points or more and less than 40 points
Δ: 23 points or more and less than 34 points
×: Less than 23 points
表1〜4に示すとおり、(A)アミノ酸系界面活性剤、(B)両親媒性エステル、並びに(C)セラミド類を含有する皮膚洗浄料組成物(実施例1〜17)は、洗い上がりの皮膚における平滑感、保湿感、及び柔軟感が総合的に優れていた。これに対し、例えば(A)成分を含まずに(a)成分(他の界面活性剤)を含む皮膚洗浄料組成物(比較例11〜20)は、保湿感や柔軟感に劣っていた。また、(B)成分を含まない皮膚洗浄料組成物(比較例1、2、5、6、9、10)は、特に保湿感が劣っていた。さらに、(C)成分を含まない皮膚洗浄料組成物(比較例1〜8)は、特に平滑感が劣っていた。 As shown in Tables 1 to 4, the skin cleansing composition (Examples 1 to 17) containing (A) an amino acid-based surfactant, (B) an amphipathic ester, and (C) ceramides was washed. The smoothness, moisturizing feeling, and softness feeling on the skin were excellent overall. On the other hand, for example, the skin cleansing composition (Comparative Examples 11 to 20) containing the component (a) (other surfactant) without containing the component (A) was inferior in moisturizing feeling and softness feeling. In addition, the skin cleansing composition containing no component (B) (Comparative Examples 1, 2, 5, 6, 9, 10) was particularly inferior in moisturizing sensation. Further, the skin cleansing composition (Comparative Examples 1 to 8) containing no component (C) was particularly inferior in smoothness.
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JP2019118268A JP2021004206A (en) | 2019-06-26 | 2019-06-26 | Skin cleansing composition |
TW109119382A TW202100137A (en) | 2019-06-26 | 2020-06-10 | Skin cleanser composition |
PCT/JP2020/023790 WO2020262160A1 (en) | 2019-06-26 | 2020-06-17 | Skin cleanser composition |
CN202080003391.6A CN112449599A (en) | 2019-06-26 | 2020-06-17 | Skin cleanser composition |
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JPH0248520A (en) * | 1988-08-10 | 1990-02-19 | Pola Chem Ind Inc | Cleaning agent |
JP2013014540A (en) * | 2011-07-04 | 2013-01-24 | Mandom Corp | Humectant cosmetic |
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JP2003321328A (en) * | 2002-04-25 | 2003-11-11 | Nicostar Co Ltd | Skin cleansing composition |
BR0305505A (en) * | 2002-07-12 | 2004-09-28 | Johnson & Johnson Gmbh | Dry products comprising an applicator and two stages |
JP2008044857A (en) * | 2006-08-11 | 2008-02-28 | Toyobo Co Ltd | Ameliorating agent for skin roughening |
JP6235844B2 (en) * | 2012-09-20 | 2017-11-22 | 花王株式会社 | Cleaning composition for skin or hair |
WO2018180009A1 (en) * | 2017-03-30 | 2018-10-04 | ビタミンC60バイオリサーチ株式会社 | Fullerene-containing cosmetic composition |
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JPH0248520A (en) * | 1988-08-10 | 1990-02-19 | Pola Chem Ind Inc | Cleaning agent |
JP2013014540A (en) * | 2011-07-04 | 2013-01-24 | Mandom Corp | Humectant cosmetic |
Non-Patent Citations (1)
Title |
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日本精化 香粧品事業本部香粧品研究開発部 勝間田 祐貴・釋氏 梨沙・清水 透: "特集/クレンジング技術の開発 Development of cleansing technology", フレグランスジャーナル FRAGRANCE JOURNAL, vol. 第44巻, JPN6023014420, ISSN: 0005033435 * |
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