JP2020529392A - 傷痕の予防または治療のための組成物 - Google Patents
傷痕の予防または治療のための組成物 Download PDFInfo
- Publication number
- JP2020529392A JP2020529392A JP2019567726A JP2019567726A JP2020529392A JP 2020529392 A JP2020529392 A JP 2020529392A JP 2019567726 A JP2019567726 A JP 2019567726A JP 2019567726 A JP2019567726 A JP 2019567726A JP 2020529392 A JP2020529392 A JP 2020529392A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- skin
- weight
- scars
- external preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/32—Manganese; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/44—Elemental carbon, e.g. charcoal, carbon black
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
- A61K8/892—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a hydroxy group, e.g. dimethiconol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
- A61K8/894—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
- A61K2800/43—Pigments; Dyes
- A61K2800/432—Direct dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
傷痕の予防用または治療用の組成物を製造するために、次のように遂行した。まず、下記表1の相A成分を常温で混合した。次に、下記表1の相B成分を混合した後、3段ローラ(roller)(Kyoung Yong Machinery Co.,Ltd.)を使用して完全分散を行った。前述のように製造した相Aと相Bとを混合した後、常温で、3段ローラを使用し、完全分散を行い、傷痕の予防用または治療用の組成物を製造した。
拡散性評価のために、比較例2と比較例3との組成物を同量取り、同一力を加え、平らな紙に塗って評価した。拡散性評価結果を図1に示した。
混合する工程により、色素が組成物内において、安定して均一に分散され、安定した剤形を有し、塗布性と拡散性とにすぐれ、皮膚に塗布するのに適する剤形であるということを確認した。
傷痕隠蔽による傷痕除去力に対する評価は、一人の腕に、赤色ペンで同一に表示した後、比較例1、比較例3及び実施例1の組成物を表示部分に同量塗布するか、あるいは何も塗布していない(対照群)ようにした後、赤色表示部分が除去された程度を確認し、その写真を図2に示した。
前記実験例2のような方法で、比較例4及び実施例1の組成物を塗布するか、あるいは塗布しないようにし(対照群)、傷痕除去力を確認した写真を図3に示した。
傷痕治療効果を評価するため、マウス5匹に、同一に傷痕を作り、傷痕の大きさを測定した。実施例1、比較例1−4の組成物を3日に1回ずつ2ヵ月間、傷痕部位に塗布した。2ヵ月後、傷痕サイズを測定し、塗布前の傷痕サイズに対する塗布後の傷痕サイズを百分率で計算し、傷痕治療効果を評価した結果を下記表2に示した。
Claims (16)
- 色素及びシリコンオイルを含む傷痕の予防または治療のための皮膚外用剤組成物。
- 前記傷痕は、過増殖性傷痕、ケロイド傷痕、萎縮性傷痕、ストレッチングマーク、またはその組み合わせでもあることを特徴とする請求項1に記載の皮膚外用剤組成物。
- 前記色素は、二酸化チタン、酸化亜鉛、酸化鉄、水酸化アルミニウム、ウルトラマリン、フェロシアン化第二鉄、フェロシアン化第二アンモニウム、酸化クロムグリーン、水酸化クロムグリーン、マイカ、カーボンブラック、マンガンバイオレット及びカーマインから構成された群から選択された1種以上であることを特徴とする請求項1に記載の皮膚外用剤組成物。
- 組成物総重量に対して、1重量%ないし30重量%の色素を含むことを特徴とする請求項1に記載の皮膚外用剤組成物。
- 前記色素がシリコンオイルに分散されたものであることを特徴とする請求項1に記載の皮膚外用剤組成物。
- 前記分散がミリング工程によるものであることを特徴とする請求項5に記載の皮膚外用剤組成物。
- 前記シリコンオイルは、ジメチコン、ポリシリコン−11、ポリシリコン−15、ポリシリコン−8、ポリシリコン−17、ヒドロゲンジメチコン、ラウリルジメチコン、シクロペンタシロキサン、シクロヘキサシロキサン、トリシロキサン、メチルトリメチコン、フェニルメチコン、ジメチコンコポリオール、ジメチコンコポリオールアセテート、シリコングリコールコポリオール、ジメチコノール、メチルポリシロキサン、メチルフェニルポリシロキサン、ジメチコンコポリオールメチルエーテル、メチルシクロポリシロキサン、ジメチルポリシロキサン、ヘキサメチルジシロキサン及びカプリリルメチルポリシロキサンから構成された群から選択された1種以上であることを特徴とする請求項1に記載の皮膚外用剤組成物。
- 組成物総重量に対して70重量%ないし99重量%のシリコンオイルを含むものであることを特徴とする請求項1に記載の皮膚外用剤組成物。
- 前記皮膚外用剤組成物は、軟膏剤、クリーム剤、ローション剤、乳剤、ゲル剤、カタプラズマ剤、ペースト剤、リニメント剤、リニメント剤、硬膏剤、芳香水剤、エアロゾール剤及びヒドロゲルから構成された群から選択された1種以上に剤形化されるものであることを特徴とする請求項1に記載の皮膚外用剤組成物。
- 傷痕を隠蔽するものであることを特徴とする請求項1に記載の皮膚外用剤組成物。
- 傷痕の予防または治療は、皮膚水分損失抑制を介するものであることを特徴とする請求項1に記載の皮膚外用剤組成物。
- 色素及びシリコンオイルを含む傷痕の予防または治療のための薬学的組成物。
- 色素及びシリコンオイルを含む傷痕の予防または治療のための化粧料組成物。
- シリコンオイルを含む第1相を得る段階(S1)と、
シリコンオイル及び色素を混合分散して第2相を得る段階(S2)と、
前記第1相及び前記第2相を混合分散する段階(S3)と、を含む皮膚外用剤の製造方法。 - 前記皮膚外用剤総重量に対して、1重量%ないし30重量%の色素を含むことを特徴とする請求項14に記載の方法。
- 前記混合分散がミリング工程によって行われることを特徴とする請求項14に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2017-0097127 | 2017-07-31 | ||
KR1020170097127A KR20190013101A (ko) | 2017-07-31 | 2017-07-31 | 흉터의 예방 또는 치료를 위한 조성물 |
PCT/KR2018/006073 WO2019027132A1 (ko) | 2017-07-31 | 2018-05-29 | 흉터의 예방 또는 치료를 위한 조성물 |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2020529392A true JP2020529392A (ja) | 2020-10-08 |
Family
ID=65233931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019567726A Pending JP2020529392A (ja) | 2017-07-31 | 2018-05-29 | 傷痕の予防または治療のための組成物 |
Country Status (6)
Country | Link |
---|---|
US (1) | US11497702B2 (ja) |
EP (1) | EP3662914A4 (ja) |
JP (1) | JP2020529392A (ja) |
KR (1) | KR20190013101A (ja) |
CN (1) | CN110740739A (ja) |
WO (1) | WO2019027132A1 (ja) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102285696B1 (ko) * | 2019-06-13 | 2021-08-04 | 신신제약 주식회사 | 흉터 예방 또는 치료를 위한 국소용 약학적 조성물 |
CN110464687A (zh) * | 2019-09-19 | 2019-11-19 | 温军海 | 一种修复妊娠纹疤痕的组合物 |
CN112587515A (zh) * | 2020-12-18 | 2021-04-02 | 张青 | 甘草黄酮类化合物在制备预防和/或治疗瘢痕的药物中的用途 |
CN113813270B (zh) * | 2021-01-21 | 2023-07-21 | 广东盛普生命科技有限公司 | 一种预防和/或治疗皮肤纤维化的药物 |
CN116869921B (zh) * | 2023-07-12 | 2024-04-16 | 上海森博生物科技有限公司 | 一种疤痕修复乳膏组合物及其制备方法和应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07165534A (ja) * | 1993-12-10 | 1995-06-27 | Ishihara Sangyo Kaisha Ltd | 鉄含有超微粒子二酸化チタン分散体 |
US20150086496A1 (en) * | 2013-09-25 | 2015-03-26 | Far Eastern New Century Corporation | Composition of scar gel |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9010526D0 (en) | 1990-05-10 | 1990-07-04 | Unilever Plc | Cosmetic composition |
KR910019596A (ko) * | 1990-05-10 | 1991-12-19 | 에이치 드 로이 | 화장제 조성물 |
WO1995009598A1 (en) | 1993-10-02 | 1995-04-13 | The Procter & Gamble Company | Cosmetic make-up compositions |
KR100835865B1 (ko) * | 2002-12-31 | 2008-06-09 | (주)아모레퍼시픽 | 이산화티탄과 산화아연의 미세 유분산액 및 이를 함유하는외용제 조성물 |
AU2006288722B2 (en) | 2005-09-09 | 2011-08-04 | The Procter & Gamble Company | Solid skin care composition comprising multiple layers |
AU2006291257A1 (en) | 2005-09-09 | 2007-03-22 | The Procter & Gamble Company | Solid skin care composition comprising multiple layers based on water-in-oil emulsions |
KR100839892B1 (ko) * | 2006-10-30 | 2008-06-19 | 주식회사 선진화학 | 구형의 이산화티탄 분말의 제조방법 |
CN101742979B (zh) * | 2007-03-08 | 2013-07-17 | 莫科治疗有限公司 | 用于预防和减少疤痕形成的敷料制剂 |
FR2913345B1 (fr) | 2007-03-09 | 2010-06-11 | Inst Francais Du Petrole | Procede et dispositif de separation en lit mobile simule a nombre de vannes et volume de lignes reduits |
WO2009109887A1 (en) | 2008-03-06 | 2009-09-11 | Philips Intellectual Property & Standards Gmbh | Method for analyzing a tube system |
KR101210371B1 (ko) * | 2012-05-18 | 2012-12-11 | 주식회사 초이스무역 | 무기계 자외선 차단제의 안정화된 유분산액 제조방법 및 이를 포함하는 화장료 조성물 |
KR20160084825A (ko) * | 2016-06-30 | 2016-07-14 | (주)제니트리 | 자외선 노출에 의한 피부 과민 반응 예방 및 개선용 조성물과 이를 이용한 화장료 |
-
2017
- 2017-07-31 KR KR1020170097127A patent/KR20190013101A/ko active Search and Examination
-
2018
- 2018-05-29 CN CN201880038941.0A patent/CN110740739A/zh active Pending
- 2018-05-29 US US16/622,640 patent/US11497702B2/en active Active
- 2018-05-29 JP JP2019567726A patent/JP2020529392A/ja active Pending
- 2018-05-29 WO PCT/KR2018/006073 patent/WO2019027132A1/ko unknown
- 2018-05-29 EP EP18840708.4A patent/EP3662914A4/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07165534A (ja) * | 1993-12-10 | 1995-06-27 | Ishihara Sangyo Kaisha Ltd | 鉄含有超微粒子二酸化チタン分散体 |
US20150086496A1 (en) * | 2013-09-25 | 2015-03-26 | Far Eastern New Century Corporation | Composition of scar gel |
Also Published As
Publication number | Publication date |
---|---|
US11497702B2 (en) | 2022-11-15 |
EP3662914A1 (en) | 2020-06-10 |
CN110740739A (zh) | 2020-01-31 |
EP3662914A4 (en) | 2021-04-07 |
WO2019027132A1 (ko) | 2019-02-07 |
US20210137819A1 (en) | 2021-05-13 |
KR20190013101A (ko) | 2019-02-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2020529392A (ja) | 傷痕の予防または治療のための組成物 | |
US8008345B2 (en) | Dermal therapy using phosphate derivatives of electron transfer agents | |
HU230156B1 (hu) | Hagymakivonatot és zsírolajat tartalmazó szer előállítása károsodott bőrszövet, különösen sebhelyek ellátására, megelőzésére vagy kezelésére | |
JP2006514657A (ja) | しわ、細かいすじ及び発汗過多の治療のための組成物及び伝達方法 | |
TW200412992A (en) | Compositions containing peptide copper complexes and phytochemical compounds, and methods related thereto | |
JPH0859463A (ja) | クマリンを含む調製物および薬剤および美容分野におけるそれらの使用 | |
JP4786630B2 (ja) | 皮膚外用剤 | |
JP2011088930A (ja) | 二酸化炭素経皮・経粘膜吸収用組成物 | |
JP2005060234A (ja) | 皮膚外用剤 | |
JP5643872B2 (ja) | 二酸化炭素経皮・経粘膜吸収用組成物 | |
JP5646477B2 (ja) | キトサンおよびジカルボン酸を含む、酒さ疾患を治療するための組成物 | |
JP5164438B2 (ja) | 二酸化炭素経皮・経粘膜吸収用組成物 | |
JP5699184B2 (ja) | 二酸化炭素経皮・経粘膜吸収用組成物 | |
JP2005060233A (ja) | 皮膚外用剤 | |
KR102113317B1 (ko) | 흉터의 예방 또는 치료를 위한 조성물 | |
KR102205025B1 (ko) | 흉터의 예방 또는 치료를 위한 조성물 | |
CN106456600B (zh) | 使用青蒿素及其衍生物治疗或预防脂溢性角化病 | |
EP1996514B1 (en) | Removal of skin changes | |
JP5993336B2 (ja) | 二酸化炭素経皮・経粘膜吸収用組成物 | |
JP2004107261A (ja) | 皮膚老化抑制化粧料 | |
JP2013177461A (ja) | 二酸化炭素経皮・経粘膜吸収用組成物 | |
JP2023064171A (ja) | 化粧料 | |
JP2011026292A (ja) | 抗酸化性化粧料 | |
BR102017008940A2 (pt) | composição hidratante para estruturas queratinosas, uso da composição e caneta aplicadora. | |
JP2003238382A (ja) | 皮膚外用剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20210409 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20211224 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20220104 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220401 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20220705 |