JP2020519413A - 組織の固定および癒合のためのインプラント - Google Patents
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/84—Fasteners therefor or fasteners being internal fixation devices
- A61B17/86—Pins or screws or threaded wires; nuts therefor
- A61B17/869—Pins or screws or threaded wires; nuts therefor characterised by an open form, e.g. wire helix
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- A—HUMAN NECESSITIES
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- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
- A61B17/7055—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant connected to sacrum, pelvis or skull
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/84—Fasteners therefor or fasteners being internal fixation devices
- A61B17/86—Pins or screws or threaded wires; nuts therefor
- A61B17/864—Pins or screws or threaded wires; nuts therefor hollow, e.g. with socket or cannulated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00526—Methods of manufacturing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30593—Special structural features of bone or joint prostheses not otherwise provided for hollow
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30621—Features concerning the anatomical functioning or articulation of the prosthetic joint
- A61F2002/30622—Implant for fusing a joint or bone material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/3085—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with a threaded, e.g. self-tapping, bone-engaging surface, e.g. external surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2002/3092—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth having an open-celled or open-pored structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30985—Designing or manufacturing processes using three dimensional printing [3DP]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30988—Other joints not covered by any of the groups A61F2/32 - A61F2/4425
- A61F2002/30995—Other joints not covered by any of the groups A61F2/32 - A61F2/4425 for sacro-iliac joints
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Abstract
Description
本願は、2017年5月12日に出願された米国仮特許出願整理番号第62/505,257号の優先権を合衆国法典第35巻第119条(e)のもとで主張する。米国仮特許出願整理番号第62/505,257号の全体は、参照することにより本願に援用される。
多様な実施形態によれば、本発明では、近位ヘッド部と、遠位先端部を有する軸部と、を含む固定用部材を有する固定用インプラントが提供される。固定用インプラントは、例えば、仙腸関節などの関節における近接する骨、または骨折断片を含むいくつかの事例で、骨組織などの組織の固定を達成するために使用されると有利である。このインプラントは、他の固定用部材の設計と比較して回転運動、回転遊動、および、引き抜きに対して強化された抵抗を提供する。なおこの利点は、インプラントの少なくとも1部分の3次元開放構造の表面積が大きく増加したことの結果としての骨係合表面の増加、オッセオインテグレーションに対する可能性の向上、骨の食いつきの強化のうちの1つまたは複数に起因する。固定用インプラントは、多様な異なる実施形態において海綿骨の開放状の相互接続された多孔性に似せてモデル化されたヘッド部および軸部の特徴のうちの1つまたは複数を含む。
Claims (20)
- 近位端部から遠位端部までの長さを有する軸部と、その近位端部において前記軸部と一体化されたヘッド部と、その遠位端部において前記軸部と一体化された先端部と、前記近位ヘッド部から前記遠位先端部までの前記近位ヘッド部を含む表面の少なくとも1部分に沿う少なくとも1つのネジ山と、を含む、固定用インプラントであって、
前記固定用インプラントは少なくとも前記軸部の少なくとも1部分に沿って1つまたは複数の開放状の網状組織体を含み、前記少なくとも1つのネジ山は前記開放状の網状組織体の表面と一体化されている開放コアをさらに含む、
固定用インプラント。 - 前記1つまたは複数の開放状の網状組織体は前記少なくとも1つのネジ山間の間隙において開放状である、請求項1に記載の固定用インプラント。
- 前記開放状の網状組織体は、螺旋、組織化された配置のトラス、ランダムな配置のトラス、開放状の相互接続された細孔の骨組み、および、ランダムな開放状の相互接続された細孔の多孔性枠組、および、これらの組み合わせを含む群よりも選択される、請求項1に記載の固定用インプラント。
- 前記軸部の少なくとも1部分に沿って前記開放状の網状組織体内の空隙を含む、請求項1に記載の固定用インプラント。
- 前記開放状の網状組織体内に、前記近位ヘッド部、前記軸部、および前記遠位先端部を含む前記近位ヘッド部、前記軸部、および前記遠位先端部からの長さに沿って貫通カニューレを含む、請求項4に記載の固定用インプラント。
- 前記開放状の網状組織体内において前記カニューレの周りの壁部をさらに含む、請求項5に記載の固定用インプラント。
- 前記壁部はソリッド状および有窓のうちの1つである、請求項6に記載の固定用インプラント。
- 前記開放状の網状組織体内の前記空隙の周りの壁部をさらに含む、請求項4に記載の固定用インプラント。
- 前記壁部はソリッド状である、請求項9に記載の固定用インプラント。
- 前記壁部は有窓である、請求項9に記載の固定用インプラント。
- 固定用インプラントの1つまたは複数の表面は多孔性および骨誘導性のうちの1つである表面処理が施されている、請求項1に記載の固定用インプラント。
- 前記開放状の網状組織体は、付加(3D)製造、従来の機械加工、および下位パーツの組み立てから選択される処理により形成される、請求項1に記載の固定用インプラント。
- 前記ヘッド部および前記軸部のうちの1つまたは両方は別個に形成され、前記固定用インプラント上のネジ山は金属から選択された物質から形成され、前記開放状の網状組織体は、PEK、PEEK、PAEKから選択された生体適合性ポリマー、生分解性ポリマー、骨材料、BMP、およびこれらの組み合わせのうちのうちの1つまたは複数を含む複合材料を使用して別個に形成される、請求項1に記載の固定用インプラント。
- ヘッド部、軸部、および遠位先端部を含む固定用インプラントであって、前記ヘッド部は、ソリッド状であり、かつ、金属およびポリマーから選択された、カニューレが挿入されたコアを有し、前記軸部は、(i)前記ヘッド部の近傍における、螺刻されず、かつ、金属およびポリマーから選択されたソリッド状のカニューレが挿入されたコアを有する、近位軸部部分と、(ii)金属およびポリマーから選択されたソリッド状のカニューレが挿入されたコアを有し、かつ、その表面の少なくとも1部分に沿って雄ネジを含む、テーパ状の遠位先端部部分と、(iii)前記螺刻されない近位軸部部分から前記テーパ状遠位先端部まで延長し、かつ雄ネジを含む、螺刻された内方成長部分と、を含み、前記開放状の網状組織体は、前記内方成長部分の長さに沿って延長し、少なくとも1つの螺旋、組織化された配置のトラス、ランダムな配置のトラス、開放状の相互接続された細孔の骨組み、ランダムな開放状の相互接続された細孔の多孔性枠組、およびこれらの組み合わせのうちの1つまたは組み合わせから選択される、固定用インプラント。
- 前記開放状本体網状組織は開放状の相互接続された細孔の骨組みを含み、前記軸部および前記遠位先端部の1部分は螺刻され、前記インプラントは金属を含む物質から形成される、請求項14に記載の固定用インプラント。
- 近位端部から遠位端部までの長さを有する軸部と、その近位端部において前記軸部と一体化されたヘッド部と、その遠位端部において前記軸部と一体化された先端部と、前記近位ヘッド部から前記遠位先端部までの前記近位ヘッド部を含む表面の少なくとも1部分に沿う少なくとも1つのネジ山と、を含む、固定用インプラントであって、
前記固定用インプラントは少なくとも前記軸部の少なくとも1部分に沿って1つまたは複数の開放状の網状組織体を含む開放コアをさらに含み、前記少なくとも1つのネジ山は前記開放状の網状組織体の表面と一体化され、前記1つまたは複数の開放状の網状組織体は前記少なくとも1つのネジ山間の間隙において開放状であり、前記開放状の網状組織体は、螺旋、組織化された配置のトラス、ランダムな配置のトラス、開放状の相互接続された細孔の骨組み、およびランダムな開放状の相互接続された細孔の多孔性枠組、およびこれらの組み合わせを含む群から選択される、
固定用インプラント。 - 前記軸部の少なくとも1部分に沿って前記開放状の網状組織体内の空隙を含む、請求項16に記載の固定用インプラント。
- 前記開放状の網状組織体内に、前記近位ヘッド部、前記軸部、および前記遠位先端部を含む前記近位ヘッド部、前記軸部、および前記遠位先端部からの長さに沿って貫通カニューレを含む、請求項17に記載の固定用インプラント。
- 前記開放状の網状組織体内において前記カニューレの周りの壁部をさらに含む、請求項18に記載の固定用インプラント。
- 前記開放状の網状組織体は、付加(3D)製造、従来の機械加工、および下位パーツの組み立てから選択される処理により形成され、前記ヘッド部および前記軸部のうちの1つまたは両方は別個に形成され、前記固定用インプラント上のネジ山は金属から選択された物質から形成され、前記開放状の網状組織体は、PEK、PEEK、PAEKから選択された生体適合性ポリマー、生分解性ポリマー、骨材料、BMP、およびこれらの組み合わせのうちの1つまたは複数を含む複合材料を使用して別個に形成される、請求項19に記載の固定用インプラント。
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PCT/US2018/032215 WO2018209177A1 (en) | 2017-05-12 | 2018-05-11 | Implants for tissue fixation and fusion |
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US11446070B2 (en) | 2022-09-20 |
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AU2018265427A1 (en) | 2019-11-28 |
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US20210196333A1 (en) | 2021-07-01 |
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