JP2020045323A5 - - Google Patents
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- Publication number
- JP2020045323A5 JP2020045323A5 JP2018177471A JP2018177471A JP2020045323A5 JP 2020045323 A5 JP2020045323 A5 JP 2020045323A5 JP 2018177471 A JP2018177471 A JP 2018177471A JP 2018177471 A JP2018177471 A JP 2018177471A JP 2020045323 A5 JP2020045323 A5 JP 2020045323A5
- Authority
- JP
- Japan
- Prior art keywords
- solifenacin succinate
- base
- containing preparation
- preparation according
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- RXZMMZZRUPYENV-DZSUWJOWSA-N 1-azabicyclo[2.2.2]octan-3-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate;butanedioic acid Chemical compound OC(=O)CCC(O)=O.C1([C@H]2C3=CC=CC=C3CCN2C(OC2C3CCN(CC3)C2)=O)=CC=CC=C1 RXZMMZZRUPYENV-DZSUWJOWSA-N 0.000 claims 10
- 229960001368 solifenacin succinate Drugs 0.000 claims 10
- 239000000654 additive Substances 0.000 claims 3
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 3
- 235000014655 lactic acid Nutrition 0.000 claims 3
- 239000004310 lactic acid Substances 0.000 claims 3
- 229940057801 Calcium Lactate Pentahydrate Drugs 0.000 claims 2
- 229920000858 Cyclodextrin Polymers 0.000 claims 2
- CIWBSHSKHKDKBQ-DUZGATOHSA-N D-isoascorbic acid Chemical compound OC[C@@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-DUZGATOHSA-N 0.000 claims 2
- 239000001116 FEMA 4028 Substances 0.000 claims 2
- 229960000448 Lactic acid Drugs 0.000 claims 2
- 229920002884 Laureth 4 Polymers 0.000 claims 2
- 230000000996 additive Effects 0.000 claims 2
- 235000011175 beta-cyclodextrine Nutrition 0.000 claims 2
- 229960004853 betadex Drugs 0.000 claims 2
- HPVJXNNKHRNBOY-UHFFFAOYSA-L calcium;2-hydroxypropanoate;pentahydrate Chemical compound O.O.O.O.O.[Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O HPVJXNNKHRNBOY-UHFFFAOYSA-L 0.000 claims 2
- 235000010350 erythorbic acid Nutrition 0.000 claims 2
- SFNALCNOMXIBKG-UHFFFAOYSA-N ethylene glycol monododecyl ether Chemical compound CCCCCCCCCCCCOCCO SFNALCNOMXIBKG-UHFFFAOYSA-N 0.000 claims 2
- 229940026239 isoascorbic acid Drugs 0.000 claims 2
- WHGYBXFWUBPSRW-FOUAGVGXSA-N β-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims 2
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2R,3R,4S,5R,6S)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2S,3R,4S,5R,6R)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2R,3R,4S,5R,6R)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 claims 1
- VUKAUDKDFVSVFT-UHFFFAOYSA-N 2-[6-[4,5-bis(2-hydroxypropoxy)-2-(2-hydroxypropoxymethyl)-6-methoxyoxan-3-yl]oxy-4,5-dimethoxy-2-(methoxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)-5-methoxyoxane-3,4-diol Chemical compound COC1C(OC)C(OC2C(C(O)C(OC)C(CO)O2)O)C(COC)OC1OC1C(COCC(C)O)OC(OC)C(OCC(C)O)C1OCC(C)O VUKAUDKDFVSVFT-UHFFFAOYSA-N 0.000 claims 1
- 239000001856 Ethyl cellulose Substances 0.000 claims 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims 1
- 235000019325 ethyl cellulose Nutrition 0.000 claims 1
- 229920001249 ethyl cellulose Polymers 0.000 claims 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 1
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 claims 1
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 claims 1
- 229920000609 methyl cellulose Polymers 0.000 claims 1
- 239000001923 methylcellulose Substances 0.000 claims 1
- 235000010981 methylcellulose Nutrition 0.000 claims 1
- 239000007962 solid dispersion Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Claims (6)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018177471A JP7198021B2 (en) | 2018-09-21 | 2018-09-21 | Preparations containing solifenacin succinate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018177471A JP7198021B2 (en) | 2018-09-21 | 2018-09-21 | Preparations containing solifenacin succinate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020045323A JP2020045323A (en) | 2020-03-26 |
| JP2020045323A5 true JP2020045323A5 (en) | 2021-08-26 |
| JP7198021B2 JP7198021B2 (en) | 2022-12-28 |
Family
ID=69900714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018177471A Active JP7198021B2 (en) | 2018-09-21 | 2018-09-21 | Preparations containing solifenacin succinate |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP7198021B2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113440492A (en) * | 2020-03-27 | 2021-09-28 | 广东东阳光药业有限公司 | Composition of muscarinic receptor antagonist and preparation method thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2146693A2 (en) | 2007-04-11 | 2010-01-27 | Dr. Reddy's Laboratories Ltd. | Solifenacin compositions |
| JP2017210422A (en) | 2016-05-24 | 2017-11-30 | ニプロ株式会社 | Pharmaceutical composition, method for producing pharmaceutical composition, and method for improving the stability of amorphous body |
| CN105919963A (en) | 2016-05-27 | 2016-09-07 | 扬子江药业集团广州海瑞药业有限公司 | Solifenacin succinate composition |
| JP6446511B2 (en) | 2016-09-02 | 2018-12-26 | 大原薬品工業株式会社 | Solid preparation containing amorphous solifenacin and antioxidant |
| JP6805699B2 (en) | 2016-10-04 | 2020-12-23 | ニプロ株式会社 | Pharmaceutical compositions, methods for producing pharmaceutical compositions, and methods for improving the stability of amorphous materials. |
| US20200221740A1 (en) | 2017-02-08 | 2020-07-16 | Rising Phoenix Industries Pty Ltd | Terminalia ferdinandiana leaf extract and products containing extract of terminalia ferdinandiana leaf |
-
2018
- 2018-09-21 JP JP2018177471A patent/JP7198021B2/en active Active
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