JP2020039868A - 省エネによるインターリーブ多接点式神経調節療法 - Google Patents
省エネによるインターリーブ多接点式神経調節療法 Download PDFInfo
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Abstract
Description
a)第一グループの電極接点を形成する2つの電極接点間に電流パルスを伝達する工程と、
b)第一グループの2つの電極接点間に荷電平衡電流パルスを伝達する工程であって、当該荷電平衡電流パルスが、前の電流パルスの振幅と同じ絶対値であるが反対極性を持つ振幅を有する工程と、
c)第二グループの電極接点を形成する少なくとも2つの電極接点間であって、電流パルスの後で荷電平衡電流パルスの前に、更なる電流パルスを伝達する工程とを有するものである。
・第一グループG1によって構成される少なくとも2つの電極E1、E3間に、振幅−Aの電流パルスCPを伝達する工程と、
・第一グループG1の荷電平衡APの前に、第二グループG2によって構成される少なくとも2つの電極E2、E4間に、振幅−Bの電流パルスCPを伝達する工程とを有する。
・次に、振幅Aの荷電平衡電流パルスAPを第一グループG1へ伝達する工程と、
・次に、振幅Bの荷電平衡電流パルスAPを第一グループG1へ伝達する工程と、
・電流パルスが循環的に反復される工程とが実行される。
Claims (15)
- 患者(P)の電気刺激を生成するための医療装置(1)であって、
・前記患者(P)の電気刺激のための電流パルスを生成するように構成されたパルス発生器(2)と、
・前記パルス発生器(2)に接続されるように構成されている少なくとも1つの電極リード線(3)であって、前記電流パルスを前記患者(P)の組織(S)へ伝達するための複数の電極接点(E1〜E8)を有する電極リード線と
を有しており、
前記パルス発生器(2)は、前記複数の電極接点のうちの第一グループ(G1)の電極接点を形成する2つの電極(E1、E3)に電流パルス(CP)を反復して伝達するように構成されており、前記パルス発生器(2)は、前記第一グループ(G1)の前記電極(E1、E3)間の各電流パルス(CP)の後、荷電平衡電流パルス(AP)を伝達し、それにより、前記それぞれの電流パルス(CP)がインターパルス間隔(II)によって前記後続の荷電平衡電流パルス(AP)から分離されるように構成されており、前記それぞれの電流パルス(CP)は、前記後続の荷電平衡電流パルス(AP)と同じ絶対値(A)であるが、反対の符号を持つ振幅を有しており、前記パルス発生器(2)は、前記複数の電極接点のうちの第二グループ(G2)の電極接点を形成する更なる2つの電極(E2、E4)間に伝達される電流パルス(CP)を、各電流パルス(CP)と前記後続の荷電平衡電流パルス(AP)との間において伝達するように構成されている、医療装置。 - 請求項1記載の医療装置において、前記パルス発生器(2)は、前記第二グループ(G2)の電極(E2、E4)間で各電流パルス(CP)が伝達された後、前記第二グループ(G2)の電極(E2、E4)間に荷電平衡電流パルス(AP)を伝達するように更に構成されており、前記第二グループ(G2)の電極(E2、E4)間に伝達される前記それぞれの電流パルス(CP)は、前記第二グループ(G2)の電極(E2、E4)間に伝達される前記後続の荷電平衡電流パルス(AP)と同じ絶対値(B)であるが、反対の符号を持つ振幅を有している、医療装置。
- 請求項1または2記載の医療装置において、前記それぞれの電流パルス(CP)はカソードの電流パルスであり、および/または前記それぞれの荷電平衡電流パルス(AP)はアノードの電流パルスである、医療装置。
- 請求項1または3記載の医療装置において、前記2つのグループ(G1、G2)の電極接点(E1、E2、E3、E4)は、前記電極リード線(3)の長手延伸方向(x)に交互に配列されており、前記パルス発生器(2)は、前記電流パルス(CP)をカソード電流パルスとして連続的に伝達し、前記電極接点の2つのグループ(G1、G2)の各電極接点は、前の電極接点のカソード電流パルス(CP)の後、並びに前の電極接点のアノード荷電平衡電流パルス(AP)の前に、カソード電流パルス(CP)を伝達するように構成されている、医療装置。
- 請求項1〜4のいずれか一項記載の医療装置において、前記医療装置(1)は埋め込み型医療装置であり、および/または前記パルス発生器(2)は、埋め込み型パルス発生器であり、および/または1つ以上の電極リード線(3)は埋め込み型電極リード線である、医療装置。
- 請求項1〜5のいずれか一項記載の医療装置において、前記パルス発生器(2)は、脊髄刺激のために電流パルスを発生するように構成されている、医療装置。
- 請求項1〜6のいずれか一項記載の医療装置において、前記複数の電極接点(E1〜E8)は全部で8つである、医療装置。
- 請求項1〜7のいずれか一項記載の医療装置において、前記パルス発生器(2)は、200Hz〜100kHzの範囲にある周波数を有する電流パルスを伝達するように構成されている、医療装置。
- 請求項1〜8のいずれか一項記載の医療装置において、前記複数の電極接点のうち1つの電極接点(E)だけが、前記第一グループ(G1)の2つの電極接点(E1、E3)間の前記電極リード線(3)に配置されており、および/または前記複数の電極接点のうち1つの電極接点(E)だけが、前記第二グループ(G2)の2つの電極接点(E2、E4)間の同じまたは第二の電極リード線(3)に配置されている、医療装置。
- 電気刺激パルスを制御する方法であって、
a)第一グループ(G1)の電極接点を形成する2つの電極接点(E1、E3)間に電流パルス(CP)を伝達する工程と、
b)前記第一グループ(G1)の2つの電極接点(E1、E3)間に荷電平衡電流パル(AP)を伝達する工程であって、前記荷電平衡電流パル(AP)が、前記前の電流パルス(CP)の振幅と同じ絶対値(A)であるが反対極性を持つ振幅を有する工程と、
c)第二グループ(G2)の電極接点を形成する更なる2つの電極接点(E2、E4)間であって、前記電流パルス(CP)の後で前記荷電平衡電流パルス(AP)の前に、更なる電流パルス(CP)を伝達する工程とを有する、方法。 - 請求項10記載の方法において、以下の工程、すなわち、
d)前記第二グループ(G2)の電極(E2、E4)間であって、前記更なる電流パルス(CP)の後に、更なる荷電平衡電流パルス(AP)を伝達する工程であって、前記更なる荷電平衡電流パルス(AP)が、前記更なる電流パルス(CP)の振幅と同じ絶対値(B)であるが反対極性を持つ振幅を有する工程を更に有する、方法。 - 請求項11記載の方法において、工程a)から始まって、工程a)〜d)が反復される、方法。
- 請求項10〜12のいずれか一項記載の方法において、前記電流パルス(CP)は連続的にカソード電流パルスとして伝達されるものであり、前記2つのグループ(G1、G2)の電極接点の各電極接点(E1、E2、E3、E4)が、前記前の電極接点のカソード電流パルス(CP)の後であって、前記前の電極接点のアノード荷電平衡電流パルスの前に、カソード電流パルス(CP)を伝達する、方法。
- 請求項10〜13のいずれか一項記載の方法において、前記グループ(G1、G2)の電極接点は、前記電極接点(E1、E2、E3、E4)を有する1つ以上の電極リード線(3)の長手延伸方向(x)に沿って重なり合っている、方法。
- 請求項9〜13のいずれか一項記載の方法において、前記電流パルス(CP)は、200Hz〜100kHzの範囲の周波数で伝達される、方法。
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Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862730574P | 2018-09-13 | 2018-09-13 | |
US62/730,574 | 2018-09-13 | ||
US201862741573P | 2018-10-05 | 2018-10-05 | |
US62/741,573 | 2018-10-05 |
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DE202010018211U1 (de) | 2009-04-22 | 2014-09-29 | Nevro Corporation | Selektive Hochfrequenzrückenmarksmodulation zur Schmerzhemmung mit weniger Nebenwirkung, sowie zugehörige Systeme |
US9895539B1 (en) | 2013-06-10 | 2018-02-20 | Nevro Corp. | Methods and systems for disease treatment using electrical stimulation |
EP3145582B1 (en) | 2014-05-20 | 2020-10-21 | Nevro Corporation | Implanted pulse generators with reduced power consumption via signal strength/duration characteristics, and associated systems |
US10300277B1 (en) | 2015-12-14 | 2019-05-28 | Nevro Corp. | Variable amplitude signals for neurological therapy, and associated systems and methods |
US11058875B1 (en) | 2018-09-19 | 2021-07-13 | Nevro Corp. | Motor function in spinal cord injury patients via electrical stimulation, and associated systems and methods |
US11590352B2 (en) | 2019-01-29 | 2023-02-28 | Nevro Corp. | Ramped therapeutic signals for modulating inhibitory interneurons, and associated systems and methods |
CN116322891A (zh) | 2020-01-25 | 2023-06-23 | 内弗洛公司 | 用于直接抑制神经细胞的***和方法 |
US20210401493A1 (en) * | 2020-06-24 | 2021-12-30 | Medtronic, Inc. | Split biphasic waveform for embolic reduction |
AU2021356705A1 (en) * | 2020-10-08 | 2023-06-08 | Medtronic, Inc. | Low energy multimodal stimulation |
AU2022226585A1 (en) * | 2021-02-24 | 2023-10-12 | Medtronic, Inc. | Neurostimulation using time-interleaved cascade of bipolar electrode combinations |
US20240207616A1 (en) * | 2021-03-31 | 2024-06-27 | Biotronik Se & Co. Kg | Multi-electrode spinal cord stimulation therapy |
TW202333820A (zh) * | 2021-12-29 | 2023-09-01 | 瑞士商諾沃庫勒有限責任公司 | 在使用交流電場治療受試者時藉由使用較大陰極和較小陽極來降低電知覺 |
CN116271516B (zh) * | 2023-03-29 | 2023-11-14 | 中国人民解放军军事科学院军事医学研究院 | 一种脊髓硬膜外植入多模式贴片电极 |
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EP3791923A1 (en) | 2021-03-17 |
CN112473001A (zh) | 2021-03-12 |
US11135427B2 (en) | 2021-10-05 |
CN110893261A (zh) | 2020-03-20 |
EP3623004A1 (en) | 2020-03-18 |
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