JP2019529081A - マイクロ流体デバイスのための流体流制御器の改良またはそれに関する改良 - Google Patents
マイクロ流体デバイスのための流体流制御器の改良またはそれに関する改良 Download PDFInfo
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- JP2019529081A JP2019529081A JP2019511914A JP2019511914A JP2019529081A JP 2019529081 A JP2019529081 A JP 2019529081A JP 2019511914 A JP2019511914 A JP 2019511914A JP 2019511914 A JP2019511914 A JP 2019511914A JP 2019529081 A JP2019529081 A JP 2019529081A
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- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00851—Additional features
- B01J2219/00858—Aspects relating to the size of the reactor
- B01J2219/0086—Dimensions of the flow channels
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00891—Feeding or evacuation
- B01J2219/00896—Changing inlet or outlet cross-section, e.g. pressure-drop compensation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
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- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
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Abstract
Description
Claims (12)
- マイクロ流体デバイスへ流体を導入するための流体流制御器であって、
入口ポートと接続ポートとの間に設けられる、少なくとも1つの高抵抗流体経路と、
前記入口ポートと前記接続ポートとの間の、少なくとも1つの低抵抗流体経路と、
前記高抵抗流体経路、前記低抵抗流体経路または両方を通る、流体流を可能にするように構成される、少なくとも1つの弁と、
を備える制御器。 - 前記高抵抗流体経路および前記低抵抗流体経路の抵抗が、以下:前記経路の断面積、前記経路の長さおよび前記経路の表面粗さ、のうちの1つまたは複数によって規定される、請求項1に記載の制御器。
- 前記高抵抗流体経路が、1つまたは複数の入口ポートを、1つまたは複数の接続ポートに連結する経路網内の1つの経路である、請求項1または2に記載の制御器。
- 各高抵抗流体経路が、対応する低抵抗流体経路を有する、請求項1または2に記載の制御器。
- 複数の高抵抗流体経路および複数の低抵抗経路が配列して設けられる、請求項1から4のいずれか一項に記載の制御器。
- 前記流体経路の前記配列を制御するための複数の弁を含むマニホールドを更に備える、請求項5に記載の制御器。
- 前記低抵抗流体経路の抵抗が、前記高抵抗流体経路の抵抗よりも少なくとも3倍小さい、請求項1から6のいずれか一項に記載の制御器。
- 前記低抵抗流体経路の抵抗が、前記高抵抗流体経路の抵抗よりも少なくとも10倍小さい、請求項1から7のいずれか一項に記載の制御器。
- 前記高抵抗流体経路が、1mbar/μl//hと1000mbar/μl/hとの間の抵抗を有する、請求項1から8のいずれか一項に記載の制御器。
- 前記低抵抗流体経路が、1×10−5mbar/μl/hrの範囲乃至100mbar/μl/hrの範囲の抵抗を有する、請求項1から9のいずれか一項に記載の制御器。
- 前記弁が、前記低抵抗流体経路だけを閉じるように構成される、請求項1から10のいずれか一項に記載の制御器。
- チップへの接点として提供される、請求項1から11のいずれか一項に記載の制御器。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1614904.9 | 2016-09-02 | ||
GB1614904.9A GB2553519B (en) | 2016-09-02 | 2016-09-02 | Improvements in or relating to a fluid flow controller for microfluidic devices |
PCT/GB2017/052552 WO2018042190A1 (en) | 2016-09-02 | 2017-09-01 | Improvements in or relating to a fluid flow controller for microfluidic devices |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2019529081A true JP2019529081A (ja) | 2019-10-17 |
JP2019529081A5 JP2019529081A5 (ja) | 2020-07-30 |
JP6823712B2 JP6823712B2 (ja) | 2021-02-03 |
Family
ID=57139825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019511914A Active JP6823712B2 (ja) | 2016-09-02 | 2017-09-01 | マイクロ流体デバイスのための流体流制御器の改良またはそれに関する改良 |
Country Status (6)
Country | Link |
---|---|
US (1) | US11285481B2 (ja) |
EP (1) | EP3507014A1 (ja) |
JP (1) | JP6823712B2 (ja) |
CN (1) | CN109803758B (ja) |
GB (1) | GB2553519B (ja) |
WO (1) | WO2018042190A1 (ja) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201219014D0 (en) | 2012-10-23 | 2012-12-05 | Cambridge Entpr Ltd | Fluidic device |
GB201320146D0 (en) | 2013-11-14 | 2014-01-01 | Cambridge Entpr Ltd | Fluidic separation and detection |
GB201511651D0 (en) | 2015-07-02 | 2015-08-19 | Cambridge Entpr Ltd | Viscosity measurements |
GB201602946D0 (en) | 2016-02-19 | 2016-04-06 | Fluidic Analytics Ltd And Cambridge Entpr Ltd | Improvements in or relating to microfluidic free-flow electrophoresis |
KR102378100B1 (ko) | 2016-04-06 | 2022-03-23 | 플루이딕 애널리틱스 리미티드 | 유동 균형의 향상 또는 이와 관련된 향상 |
GB2553780A (en) | 2016-09-12 | 2018-03-21 | Fluidic Analytics Ltd | Improvements in or relating to a device and a method for labelling a component |
GB201615472D0 (en) | 2016-09-12 | 2016-10-26 | Fluidic Analytics Ltd | Improvements in or relating to a reagent cartridge |
GB201615452D0 (en) | 2016-09-12 | 2016-10-26 | Fluidic Analytics Ltd | Improvements in or relating to valves for microfluidics devices |
US11524292B2 (en) | 2019-02-21 | 2022-12-13 | International Business Machines Corporation | Programmable hydraulic resistor array for microfluidic chips |
Citations (8)
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JPS53145894U (ja) * | 1977-04-20 | 1978-11-16 | ||
JPH0240441U (ja) * | 1988-09-10 | 1990-03-19 | ||
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WO2016010861A1 (en) * | 2014-07-14 | 2016-01-21 | President And Fellows Of Harvard College | Systems and methods for improved performance of fluidic and microfluidic systems |
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CN102215967A (zh) * | 2008-11-13 | 2011-10-12 | 皇家飞利浦电子股份有限公司 | 微流体***的入口与毛细管通道的连接 |
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GB201219014D0 (en) | 2012-10-23 | 2012-12-05 | Cambridge Entpr Ltd | Fluidic device |
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GB201511651D0 (en) | 2015-07-02 | 2015-08-19 | Cambridge Entpr Ltd | Viscosity measurements |
GB201602946D0 (en) | 2016-02-19 | 2016-04-06 | Fluidic Analytics Ltd And Cambridge Entpr Ltd | Improvements in or relating to microfluidic free-flow electrophoresis |
KR102378100B1 (ko) * | 2016-04-06 | 2022-03-23 | 플루이딕 애널리틱스 리미티드 | 유동 균형의 향상 또는 이와 관련된 향상 |
CN109475862A (zh) | 2016-06-27 | 2019-03-15 | 流体分析有限公司 | 样品装载到微流体装置中或与样品装载到微流体装置中相关的改进 |
GB201615452D0 (en) | 2016-09-12 | 2016-10-26 | Fluidic Analytics Ltd | Improvements in or relating to valves for microfluidics devices |
GB201615472D0 (en) | 2016-09-12 | 2016-10-26 | Fluidic Analytics Ltd | Improvements in or relating to a reagent cartridge |
GB2553780A (en) | 2016-09-12 | 2018-03-21 | Fluidic Analytics Ltd | Improvements in or relating to a device and a method for labelling a component |
-
2016
- 2016-09-02 GB GB1614904.9A patent/GB2553519B/en not_active Expired - Fee Related
-
2017
- 2017-09-01 CN CN201780053779.5A patent/CN109803758B/zh active Active
- 2017-09-01 US US16/329,292 patent/US11285481B2/en active Active
- 2017-09-01 JP JP2019511914A patent/JP6823712B2/ja active Active
- 2017-09-01 EP EP17762186.9A patent/EP3507014A1/en active Pending
- 2017-09-01 WO PCT/GB2017/052552 patent/WO2018042190A1/en unknown
Patent Citations (8)
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JPS53145894U (ja) * | 1977-04-20 | 1978-11-16 | ||
JPH0240441U (ja) * | 1988-09-10 | 1990-03-19 | ||
US6637463B1 (en) * | 1998-10-13 | 2003-10-28 | Biomicro Systems, Inc. | Multi-channel microfluidic system design with balanced fluid flow distribution |
WO2005118138A1 (en) * | 2004-06-04 | 2005-12-15 | Crystal Vision Microsystems Llc | Device and process for continuous on-chip flow injection analysis |
JP2007136253A (ja) * | 2005-11-14 | 2007-06-07 | Hitachi Plant Technologies Ltd | マイクロリアクタシステム |
JP2008122233A (ja) * | 2006-11-13 | 2008-05-29 | Konica Minolta Medical & Graphic Inc | マイクロ総合分析チップおよびマイクロ総合分析システム |
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WO2016010861A1 (en) * | 2014-07-14 | 2016-01-21 | President And Fellows Of Harvard College | Systems and methods for improved performance of fluidic and microfluidic systems |
Also Published As
Publication number | Publication date |
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WO2018042190A1 (en) | 2018-03-08 |
US20190247855A1 (en) | 2019-08-15 |
GB2553519A (en) | 2018-03-14 |
CN109803758B (zh) | 2021-10-15 |
EP3507014A1 (en) | 2019-07-10 |
GB2553519B (en) | 2019-12-18 |
CN109803758A (zh) | 2019-05-24 |
GB201614904D0 (en) | 2016-10-19 |
JP6823712B2 (ja) | 2021-02-03 |
US11285481B2 (en) | 2022-03-29 |
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