JP2018153557A - Melting device - Google Patents

Melting device Download PDF

Info

Publication number
JP2018153557A
JP2018153557A JP2017054678A JP2017054678A JP2018153557A JP 2018153557 A JP2018153557 A JP 2018153557A JP 2017054678 A JP2017054678 A JP 2017054678A JP 2017054678 A JP2017054678 A JP 2017054678A JP 2018153557 A JP2018153557 A JP 2018153557A
Authority
JP
Japan
Prior art keywords
dialysis
timing
predicted
powder
additional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017054678A
Other languages
Japanese (ja)
Other versions
JP6831279B2 (en
Inventor
正倫 坂巻
Masamichi Sakamaki
正倫 坂巻
良平 松本
Ryohei Matsumoto
良平 松本
鈴木　宏章
Hiroaki Suzuki
宏章 鈴木
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nikkiso Co Ltd
Original Assignee
Nikkiso Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nikkiso Co Ltd filed Critical Nikkiso Co Ltd
Priority to JP2017054678A priority Critical patent/JP6831279B2/en
Priority to CN201810235876.2A priority patent/CN108619925B/en
Publication of JP2018153557A publication Critical patent/JP2018153557A/en
Application granted granted Critical
Publication of JP6831279B2 publication Critical patent/JP6831279B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F21/00—Dissolving
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/1666—Apparatus for preparing dialysates by dissolving solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F21/00—Dissolving
    • B01F21/30—Workflow diagrams or layout of plants, e.g. flow charts; Details of workflow diagrams or layout of plants, e.g. controlling means

Abstract

PROBLEM TO BE SOLVED: To provide a melting device which allows a worker to grasp in advance, a put-in timing of a powdered drug for dialysis to be added.SOLUTION: There is provided a melting device 1 comprising melting tanks (2, 3) capable of storing a prescribed amount of stock solution for dialysis, and in dialysis treatment, following to feeding of the stock solution for dialysis in the melting tank to plural dialysis devices for performing dialysis treatment to a patient, putting a prescribed amount of the powdered drug for dialysis to be added and melting the same, the melting device further comprising: storage means 5 for storing a timing when the powdered drug for dialysis has been put in a past dialysis treatment time, as an actual putting timing; prediction means 7 for predicting a timing when the powdered drug for dialysis to be added may be put in a dialysis treatment which is going to be performed, as a predicted putting timing, based on the actual putting timing stored in the storage means 5; and display means 8 for displaying a predicted putting timing predicted by the prediction means 7.SELECTED DRAWING: Figure 5

Description

本発明は、透析用粉末剤を溶解して透析用原液を得るための溶解装置に関するものである。   The present invention relates to a dissolution apparatus for dissolving a dialysis powder to obtain a dialysis stock solution.

病院等で腎不全患者の治療に使用される透析液は、一般に重炭酸塩系と酢酸系とに区分され、このうち重炭酸塩系の透析液は、重炭酸ナトリウムを含まないもの（以下、Ａ剤という。）と重炭酸ナトリウム（以下、Ｂ剤という。）の２種類の剤に水を混合して調整されるものである。近年、運搬性向上の観点から、これらＡ剤及びＢ剤を粉末化したもの（以下、「透析用粉末剤」という。）を透析治療直前や透析治療中に溶解する試みがなされている。   Dialysis fluids used for the treatment of patients with renal failure in hospitals are generally divided into bicarbonate and acetic acid. Of these, bicarbonate-based dialysate does not contain sodium bicarbonate (hereinafter referred to as “bicarbonate”). It is prepared by mixing water with two types of agents, A agent) and sodium bicarbonate (hereinafter referred to as B agent). In recent years, from the viewpoint of improving transportability, attempts have been made to dissolve these A and B agents in powder form (hereinafter referred to as “dialysis powder”) immediately before or during dialysis treatment.

すなわち、透析用粉末剤を溶解して作製される原液（Ａ剤を溶解したＡ原液やＢ剤を溶解したＢ原液）は、清浄性の観点から溶解後にできるだけ早く治療に使用することが好ましく、特にＢ原液は、経時的に成分が変化する虞があるため、作り置きして長時間放置しておくことは好ましくないことから、透析治療直前にＡ原液やＢ原液を作製する必要があり、さらに、透析治療中においてＡ原液やＢ原液が不足した場合、それぞれの原液を追加で作製する必要がある。   That is, a stock solution prepared by dissolving a powder for dialysis (A stock solution in which agent A is dissolved or B stock solution in which agent B is dissolved) is preferably used for treatment as soon as possible after dissolution from the viewpoint of cleanliness, In particular, since the B stock solution may change its components over time, it is not preferable to leave it for a long time, so it is necessary to prepare the A stock solution and the B stock solution immediately before dialysis treatment. Furthermore, when the A stock solution and the B stock solution are insufficient during dialysis treatment, it is necessary to prepare each stock solution additionally.

このように、透析治療毎に溶解作業が必要となることから、従来から溶解のための溶解装置が各種提案されている。例えば特許文献１〜３には、２つの溶解槽を併設した溶解装置が開示されており、かかる構成により、透析治療中において、一方の溶解槽から透析液原液を透析装置側に送液している間に、他方の溶解槽に透析用粉末剤を投入させて透析用粉末剤の追加溶解を行うことができる。   As described above, since a dissolution operation is required for each dialysis treatment, various dissolution apparatuses for dissolution have been proposed. For example, Patent Documents 1 to 3 disclose a dissolution apparatus provided with two dissolution tanks. With this configuration, during dialysis treatment, a dialysate stock solution is sent from one dissolution tank to the dialyzer side. Meanwhile, the dialysis powder agent can be added to the other dissolution tank to perform additional dissolution of the dialysis powder agent.

特開２００１−９０２８号公報JP 2001-9028 A 特開２０１６−１９６６８号公報JP 2016-19668 A 特開２０１６−１９６６９号公報JP 2016-19669 A

しかしながら、上記従来技術においては、溶解槽内に収容された透析用粉末剤が所定の液位を下回った際、これを液位センサ等にて検出して医療従事者等の作業者に対して報知することにより、透析用粉末剤を追加で投入させ得る構成とされているものの、追加の透析用粉末剤の投入タイミングを予め把握させることができない構成であった。よって、作業者が他の作業を行っている最中であっても優先して透析用粉末剤の追加投入を行う必要があり、早急に対応できない場合、透析用原液が不足してしまう虞があった。   However, in the above prior art, when the dialysis powder contained in the dissolution tank falls below a predetermined liquid level, this is detected by a liquid level sensor or the like to an operator such as a medical worker. Although it is configured such that the dialysis powder can be additionally charged by notifying, the timing of adding the additional dialysis powder cannot be grasped in advance. Therefore, it is necessary to preferentially add the dialysis powder even when the operator is performing other work, and if the dialysis stock solution cannot be dealt with immediately, there is a risk that the dialysis stock solution will be insufficient. there were.

本発明は、このような事情に鑑みてなされたもので、追加の透析用粉末剤の投入タイミングを作業者に対して予め把握させることができる溶解装置を提供することにある。   This invention is made | formed in view of such a situation, and is providing the melt | dissolution apparatus which can make an operator grasp | ascertain beforehand the injection | throwing-in timing of the powder agent for additional dialysis.

請求項１記載の発明は、透析用粉末剤を溶解して透析用原液を得るとともに、その溶解された透析用原液を所定量収容し得る溶解槽を具備し、透析治療中、患者に透析治療を施すための複数の透析装置側に前記溶解槽の透析用原液を送液するのに伴って、追加の透析用粉末剤を所定量毎に投入させて溶解し得る溶解装置において、過去の透析治療中における追加の透析用粉末剤を投入したタイミングを実績投入タイミングとして記憶し得る記憶手段と、前記記憶手段で記憶された実績投入タイミングに基づいて、これから行われる透析治療中における追加の透析用粉末剤を投入するタイミングを予測投入タイミングとして予測し得る予測手段と、前記予測手段で予測された予測投入タイミングを表示し得る表示手段とを具備したことを特徴とする。   The invention according to claim 1 comprises a dissolution tank capable of obtaining a dialysis stock solution by dissolving a dialysis powder, and storing a predetermined amount of the dissolved dialysis stock solution. In a dissolution apparatus that can be charged with a predetermined amount of additional dialysis powder as the stock solution for dialysis in the dissolution tank is fed to a plurality of dialysis apparatus sides for performing dialysis in the past, Storage means for storing the timing when the additional powder for dialysis during the treatment is introduced as the actual input timing, and additional dialysis during the dialysis treatment to be performed based on the actual input timing stored in the storage means Characterized by comprising: a predicting unit that can predict the timing of charging the powder agent as a predicted charging timing; and a display unit that can display the predicted charging timing predicted by the predicting unit. That.

請求項２記載の発明は、請求項１記載の溶解装置において、透析治療において必要とされる透析用粉末剤の総量を入力し得るとともに、入力された透析用粉末剤の総量に基づいて、透析用粉末剤を追加投入すべき追加回数と、各追加投入タイミングで投入すべき透析用粉末剤の追加量とを設定し得る設定手段を具備し、前記表示手段は、前記予測投入タイミングと併せて前記設定手段で設定された追加回数及び追加量を表示可能とされたことを特徴とする。   According to a second aspect of the present invention, in the dissolution apparatus according to the first aspect, the total amount of the dialysis powder required in dialysis treatment can be input, and the dialysis is performed based on the input total amount of the dialysis powder. A setting means capable of setting the additional number of times to add the powder for dialysis and the additional amount of the powder for dialysis to be added at each additional charging timing, and the display means together with the predicted charging timing The number of additions and the addition amount set by the setting means can be displayed.

請求項３記載の発明は、請求項２記載の溶解装置において、前記設定手段で設定された追加回数又は追加量を任意に変更可能とされるとともに、前記予測手段は、当該変更に対応して前記予測投入タイミングを修正し、その修正された予測投入タイミングを前記表示手段にて表示させ得ることを特徴とする。   According to a third aspect of the present invention, in the melting apparatus according to the second aspect, the number of additions or the additional amount set by the setting means can be arbitrarily changed, and the prediction means corresponds to the change. The predicted insertion timing may be corrected, and the corrected predicted insertion timing may be displayed on the display means.

請求項４記載の発明は、請求項２又は３記載の溶解装置において、前記溶解槽内に収容された透析用原液の液位を連続的且つリアルタイムに検出可能な液位検出手段と、前記液位検出手段で検出された透析用原液の液位に基づいて前記透析用粉末剤の追加投入タイミングを報知し得る報知手段とを具備するとともに、前記予測手段は、前記報知手段で報知された追加投入タイミングに基づいて次回以降の前記予測投入タイミングを修正し、その修正された予測投入タイミングを前記表示手段にて表示させ得ることを特徴とする。   According to a fourth aspect of the present invention, there is provided the dissolution apparatus according to the second or third aspect, wherein the liquid level detection means capable of continuously and in real time detecting the liquid level of the dialysis stock solution stored in the dissolution tank; And a notifying means capable of notifying the addition timing of the dialysis powder based on the liquid level of the dialysis stock solution detected by the position detecting means, and the predicting means is the additional information notified by the notifying means. The predicted input timing after the next time is corrected based on the input timing, and the corrected predicted input timing can be displayed on the display means.

請求項５記載の発明は、請求項１〜４の何れか１つに記載の溶解装置において、前記記憶手段は、医療施設における患者の治療日程に対応した特定の治療日毎に前記実績投入タイミングを記憶するとともに、前記予測手段は、当該特定の治療日毎の予測投入タイミングを予測して前記表示手段で表示させ得ることを特徴とする。   According to a fifth aspect of the present invention, in the melting apparatus according to any one of the first to fourth aspects, the storage means sets the actual input timing for each specific treatment day corresponding to a treatment schedule of a patient in a medical facility. While storing, the said prediction means can predict the prediction injection | throwing-in timing for the said specific treatment day, and can display it on the said display means.

請求項６記載の発明は、請求項１〜５の何れか１つに記載の溶解装置において、前記表示手段で表示される予測投入タイミングは、時刻又は溶解開始時からの経過時間とされることを特徴とする。   According to a sixth aspect of the present invention, in the melting apparatus according to any one of the first to fifth aspects, the predicted charging timing displayed by the display means is a time or an elapsed time from the start of melting. It is characterized by.

請求項１の発明によれば、過去の透析治療中における追加の透析用粉末剤を投入したタイミングを実績投入タイミングとして記憶し得る記憶手段と、記憶手段で記憶された実績投入タイミングに基づいて、これから行われる透析治療中における追加の透析用粉末剤を投入するタイミングを予測投入タイミングとして予測し得る予測手段と、予測手段で予測された予測投入タイミングを表示し得る表示手段とを具備したので、追加の透析用粉末剤の投入タイミングを作業者に対して予め把握させることができる。   According to the invention of claim 1, based on the storage unit that can store the timing when the additional dialysis powder during the past dialysis treatment is input as the actual input timing, and the actual input timing stored in the storage unit, Since the prediction means that can predict the timing of adding the additional dialysis powder during dialysis treatment to be performed as the predicted input timing, and the display means that can display the predicted input timing predicted by the prediction means, It is possible to make the operator know in advance the timing of adding the additional dialysis powder.

請求項２の発明によれば、透析治療において必要とされる透析用粉末剤の総量を入力し得るとともに、入力された透析用粉末剤の総量に基づいて、透析用粉末剤を追加投入すべき追加回数と、各追加投入タイミングで投入すべき透析用粉末剤の追加量とを設定し得る設定手段を具備し、表示手段は、予測投入タイミングと併せて設定手段で設定された追加回数及び追加量を表示可能とされたので、追加回数及び追加量と併せて追加の透析用粉末剤の投入タイミングを作業者に対して予め把握させることができる。   According to the invention of claim 2, the total amount of dialysis powder required in dialysis treatment can be input, and the dialysis powder should be additionally charged based on the input total amount of dialysis powder. It has setting means that can set the number of additions and the additional amount of dialysis powder to be added at each additional charging timing, and the display means adds the number of additional times set by the setting means together with the predicted charging timing. Since the amount can be displayed, it is possible to make the operator know in advance the timing of adding the additional dialysis powder together with the number of additions and the additional amount.

請求項３の発明によれば、設定手段で設定された追加回数又は追加量を任意に変更可能とされるとともに、予測手段は、当該変更に対応して予測投入タイミングを修正し、その修正された予測投入タイミングを表示手段にて表示させ得るので、追加回数又は追加量の変更に伴う予測投入タイミングのずれを自動的に修正して表示させることができる。   According to the invention of claim 3, the number of additions or the addition amount set by the setting means can be arbitrarily changed, and the prediction means corrects the predicted insertion timing in response to the change, and the correction is made. Since the predicted insertion timing can be displayed by the display means, the deviation of the predicted insertion timing accompanying the change in the number of additions or the addition amount can be automatically corrected and displayed.

請求項４の発明によれば、溶解槽内に収容された透析用原液の液位を連続的且つリアルタイムに検出可能な液位検出手段と、液位検出手段で検出された透析用原液の液位に基づいて透析用粉末剤の追加投入タイミングを報知し得る報知手段とを具備するとともに、予測手段は、報知手段で報知された追加投入タイミングに基づいて次回以降の予測投入タイミングを修正し、その修正された予測投入タイミングを表示手段にて表示させ得るので、予測投入タイミングが報知手段で報知された実際の追加投入タイミングに対してずれた場合、そのずれを修正して表示させることができ、予測投入タイミングを精度よく予測することができる。   According to invention of Claim 4, the liquid level detection means which can detect continuously and in real time the liquid level of the dialysis stock solution accommodated in the dissolution tank, and the liquid of the dialysis stock solution detected by the liquid level detection means And a notification means that can notify the additional charging timing of the dialysis powder based on the position, and the prediction means corrects the predicted charging timing from the next time on the basis of the additional charging timing notified by the notification means, Since the corrected predicted charging timing can be displayed on the display means, if the predicted charging timing deviates from the actual additional charging timing notified by the notifying means, the shift can be corrected and displayed. Thus, it is possible to accurately predict the predicted input timing.

請求項５の発明によれば、記憶手段は、医療施設における患者の治療日程に対応した特定の治療日毎に実績投入タイミングを記憶するとともに、予測手段は、当該特定の治療日毎の予測投入タイミングを予測して表示手段で表示させ得るので、患者の治療日程が予め決まっている透析治療において、予測投入タイミングをより精度よく予測することができる。   According to the invention of claim 5, the storage means stores the actual input timing for each specific treatment day corresponding to the treatment schedule of the patient in the medical facility, and the prediction means stores the predicted input timing for each specific treatment day. Since it can be predicted and displayed on the display means, the predicted injection timing can be predicted with higher accuracy in the dialysis treatment in which the treatment schedule of the patient is determined in advance.

請求項６の発明によれば、表示手段で表示される予測投入タイミングは、時刻又は溶解開始時からの経過時間とされるので、追加の透析用粉末剤の投入タイミングを作業者に対してより正確に把握させることができる。   According to the sixth aspect of the present invention, since the predicted charging timing displayed by the display means is the time or the elapsed time from the start of dissolution, the charging timing of the additional dialysis powder is more determined by the operator. It can be grasped accurately.

本発明の実施形態に係る溶解装置を示す斜視図The perspective view which shows the melt | dissolution apparatus which concerns on embodiment of this invention. 同溶解装置を示す３面図Three-side view showing the dissolution apparatus 図２におけるＩＩＩ−ＩＩＩ線断面図Sectional view taken along line III-III in FIG. 同溶解装置が適用される血液浄化システムを示す模式図Schematic diagram showing a blood purification system to which the dissolution apparatus is applied 同溶解装置の構成を概念的に示す模式図Schematic diagram conceptually showing the structure of the dissolution apparatus 同溶解装置の構成（給水）を概念的に示す模式図Schematic diagram conceptually showing the structure (water supply) of the dissolution apparatus 同溶解装置の構成（給水及び溶解）を概念的に示す模式図Schematic diagram conceptually showing the structure (water supply and dissolution) of the dissolution apparatus 同溶解装置の構成（溶解及び循環）を概念的に示す模式図Schematic diagram conceptually showing the structure (dissolution and circulation) of the dissolution apparatus 同溶解装置の構成（送液）を概念的に示す模式図Schematic diagram conceptually showing the structure (liquid feeding) of the dissolution apparatus 同溶解装置の構成（送液切り替え及び給水）を概念的に示す模式図Schematic diagram conceptually showing the configuration of the dissolution apparatus (liquid feed switching and water supply) 同溶解装置の構成（追加投入）を概念的に示す模式図Schematic diagram conceptually showing the configuration (additional charging) of the dissolution apparatus 同溶解装置の構成（送液切り替え及び移送）を概念的に示す模式図Schematic diagram conceptually showing the structure of the dissolution apparatus (liquid transfer switching and transfer) 同溶解装置における表示手段による表示内容（メニュー画面）を示す模式図Schematic diagram showing the display contents (menu screen) by the display means in the dissolution apparatus 同溶解装置における表示手段による表示内容（予測投入タイミング等の表示）を示す模式図Schematic diagram showing the contents displayed by the display means (display of predicted charging timing, etc.) in the dissolution apparatus 同表示手段による表示内容（追加量の変更時の表示）を示す模式図Schematic diagram showing the display content (display when changing the additional amount) by the display means 同表示手段による表示内容（追加量及び追加回数の変更時の表示）を示す模式図Schematic diagram showing the content displayed by the same display means (display when changing the amount added and the number of times added) 同溶解装置における予測投入タイミングの修正時の制御内容を示すフローチャートThe flowchart which shows the control content at the time of correction of the prediction charging timing in the same dissolution device 同溶解装置における予測投入タイミングの修正時の制御内容を示すフローチャートThe flowchart which shows the control content at the time of correction of the prediction charging timing in the same dissolution device 同溶解装置の記憶手段で記憶された過去の透析治療時における透析用原液の経時的な消費傾向を示すグラフThe graph which shows the time-dependent consumption tendency of the stock solution for dialysis at the time of the past dialysis treatment memorize | stored in the memory | storage means of the dissolution apparatus 本発明の他の実施形態に係る溶解装置を示す模式図The schematic diagram which shows the melt | dissolution apparatus which concerns on other embodiment of this invention.

以下、本発明の実施形態について図面を参照しながら具体的に説明する。
本実施形態に係る溶解装置は、透析用粉末剤を溶解し透析用原液を得るものであって、図１〜５に示すように、透析用粉末剤を溶解して透析用原液を得るとともに、その溶解された透析用原液を所定量収容し得る第１溶解槽２及び第２溶解槽３と、入力手段４と、記憶手段５と、設定手段６と、予測手段７と、表示手段８と、液位検出手段９と、報知手段１０とを有して構成されている。 Hereinafter, embodiments of the present invention will be specifically described with reference to the drawings.
The dissolution apparatus according to the present embodiment dissolves the dialysis powder and obtains a dialysis stock solution. As shown in FIGS. 1 to 5, the dialysis powder is dissolved to obtain a dialysis stock solution. A first dissolution tank 2 and a second dissolution tank 3 capable of storing a predetermined amount of the dissolved stock solution for dialysis, an input means 4, a storage means 5, a setting means 6, a prediction means 7, a display means 8; The liquid level detection means 9 and the notification means 10 are provided.

第１溶解槽２は、重炭酸ナトリウムを含まないもの（Ａ剤）又は重炭酸ナトリウム（Ｂ剤）の２種類のうち何れかから成る透析用粉末剤を投入可能な収容空間を有するとともに、給水源から延設された給水ラインＬ１が接続されている。かかる給水ラインＬ１には、図５に示すように、電磁弁等から成るバルブＶ１が配設されており、このバルブＶ１を開状態とすることにより第１溶解槽２内に給水可能とされている。しかして、給水源から所定量の水を第１溶解槽２内に供給して収容させた後、その水の量に対して決められた量（規定量）の透析用粉末剤を第１溶解槽２に投入することにより、所定量及び所定濃度の透析用原液を得ることができる。   The first dissolution tank 2 has a storage space into which a powder for dialysis consisting of either one of sodium bicarbonate-free (A agent) or sodium bicarbonate (B agent) can be charged, and is supplied. A water supply line L1 extending from the water source is connected. As shown in FIG. 5, the water supply line L1 is provided with a valve V1 composed of an electromagnetic valve or the like. By opening the valve V1, water can be supplied into the first dissolution tank 2. Yes. Thus, after supplying a predetermined amount of water from the water supply source into the first dissolution tank 2 and storing it, the amount of dialysis powder prescribed for the amount of the water (specified amount) is first dissolved. By introducing it into the tank 2, a dialysis stock solution having a predetermined amount and a predetermined concentration can be obtained.

第２溶解槽３は、第１溶解槽２に投入される透析用粉末剤と同種の透析用粉末剤を投入可能な空間を有するとともに、図５に示すように、当該第２溶解槽３と第１溶解槽２とを連結する接続ラインＬ４が接続されている。かかる接続ラインＬ４には、電磁弁等からなるバルブＶ２、Ｖ３、Ｖ４が配設されており、これらバルブＶ２、Ｖ３、Ｖ４を開状態にすることにより、第１溶解槽２内の液体を第２溶解槽３内に移送可能とされている。なお、本実施形態に係る第２溶解槽３は、第１溶解槽２に比べて相対的に容量が小さなタンクとされ、オーバーフローラインＬ５にて第１溶解槽２に接続されている。   The second dissolution tank 3 has a space in which the same type of dialysis powder as the dialysis powder charged in the first dissolution tank 2 can be charged, and as shown in FIG. A connection line L4 that connects the first dissolution tank 2 is connected. The connection line L4 is provided with valves V2, V3, V4 made of electromagnetic valves or the like. By opening these valves V2, V3, V4, the liquid in the first dissolution tank 2 is supplied to the connection line L4. 2 It can be transferred into the dissolution tank 3. In addition, the 2nd dissolution tank 3 which concerns on this embodiment is made into a tank with a comparatively small capacity | capacitance compared with the 1st dissolution tank 2, and is connected to the 1st dissolution tank 2 by the overflow line L5.

また、第１溶解槽２は、給水ラインＬ１及び接続ラインＬ４の他、接続ラインＬ２が接続されている。かかる接続ラインＬ２は、一端が第１溶解槽２に接続されるとともに、他端が接続ラインＬ４における接続部ｂ（バルブＶ２とバルブＶ３との間の位置）に接続されている。さらに、接続ラインＬ２における接続部ａ（ポンプＰ１の配設部位と接続部ｂとの間の位置）には、送液ラインＬ３の基端が接続されている。かかる送液ラインＬ３は、ポンプＰ２が配設されるとともに、電磁弁等から成るバルブＶ５が配設されている。なお、送液ラインＬ３と接続ラインＬ４との間には、電磁弁等から成るバルブＶ６が配設された接続ラインＬ６が接続されている。   The first dissolution tank 2 is connected to a connection line L2 in addition to the water supply line L1 and the connection line L4. One end of the connection line L2 is connected to the first dissolution tank 2, and the other end is connected to a connection portion b (position between the valve V2 and the valve V3) in the connection line L4. Furthermore, the base end of the liquid feeding line L3 is connected to the connection part a (position between the arrangement | positioning site | part of the pump P1 and the connection part b) in the connection line L2. The liquid supply line L3 is provided with a pump P2 and a valve V5 including an electromagnetic valve. A connection line L6 in which a valve V6 made of an electromagnetic valve or the like is disposed is connected between the liquid feeding line L3 and the connection line L4.

送液ラインＬ３は、その途中にポンプＰ２が配設されるとともに、先端が透析液供給装置Ｂ（図４参照）に接続されており、溶解装置１で作製された透析用原液を透析液供給装置Ｂに送液可能とされている。かかる透析液供給装置Ｂは、溶解装置１から送液された透析用原液を所定濃度に希釈して透析液を作製するもので、図４に示すように、配管を介して複数の透析装置Ａに接続されている。しかして、溶解装置１で作製された透析用原液は、透析液供給装置Ｂで所定濃度の透析液とされ、各透析装置Ａに送液されて透析治療が施されるようになっている。   The liquid feed line L3 is provided with a pump P2 in the middle thereof, and the tip is connected to the dialysate supply device B (see FIG. 4), and the dialysate stock solution prepared by the dissolving device 1 is supplied to the dialysate. Liquid feeding to the apparatus B is possible. The dialysis fluid supply device B is a device for preparing a dialysis fluid by diluting the dialysis stock solution sent from the dissolving device 1 to a predetermined concentration. As shown in FIG. It is connected to the. Thus, the dialysis stock solution produced by the dissolution apparatus 1 is made into a predetermined concentration of dialysis liquid by the dialysis liquid supply apparatus B, and is sent to each dialysis apparatus A for dialysis treatment.

液位検出手段９は、第１溶解槽２に配設されたセンサから成るもので、第１溶解槽２内に収容された透析用原液の液位を連続的且つリアルタイムに検出可能なものである。本実施形態に係る液位検出手段９は、第１溶解槽２内に収容された液体の液面に浮いて上下移動可能な浮き手段を有した磁歪式リニア変位センサで構成されており、浮き手段の位置を連続的且つリアルタイムに検出することにより、液面（すなわち液位）を検知可能とされている。   The liquid level detection means 9 comprises a sensor disposed in the first dissolution tank 2 and can detect the liquid level of the dialysis stock solution stored in the first dissolution tank 2 continuously and in real time. is there. The liquid level detection means 9 according to the present embodiment is composed of a magnetostrictive linear displacement sensor having a floating means that floats on the liquid surface of the liquid stored in the first dissolution tank 2 and can move up and down. By detecting the position of the means continuously and in real time, the liquid level (that is, the liquid level) can be detected.

なお、液位検出手段９は、第１溶解槽２内に収容された透析用原液（供給された水又は溶液であってもよい）の液位を連続的且つリアルタイムに検出可能なものであれば、接触式又は非接触式のどちらのタイプでもよく、本実施形態の如く浮き手段による磁歪式リニア変位センサの他、超音波センサ等により構成するようにしてもよい。また、本実施形態においては、液位検出手段９が第１溶解槽２のみに配設されているが、当該第１溶解槽２と共に第２溶解槽３にも配設するようにしてもよい。   The liquid level detecting means 9 is capable of continuously and in real time detecting the liquid level of the dialysis stock solution (which may be supplied water or solution) accommodated in the first dissolution tank 2. For example, either a contact type or a non-contact type may be used, and it may be configured by an ultrasonic sensor or the like in addition to the magnetostrictive linear displacement sensor by the floating means as in this embodiment. Further, in the present embodiment, the liquid level detecting means 9 is disposed only in the first dissolution tank 2, but it may be disposed in the second dissolution tank 3 together with the first dissolution tank 2. .

さらに、液位検出手段９は、報知手段１０と電気的に接続されている。かかる報知手段１０は、液位検出手段９で検出された透析用原液の液位に基づいて透析用粉末剤の追加投入タイミングを報知し得るもので、音声や効果音等を出力させるスピーカや警告灯などから構成されている。すなわち、液位検出手段９にて検出された液位が所定の高さより低く、透析用原液が不足すると予測される時点において、報知手段１０にて報知することにより、追加の透析用粉末剤を医療従事者等の作業者に投入させ、追加溶解することにより透析用原液を追加で作製することができるのである。   Further, the liquid level detection means 9 is electrically connected to the notification means 10. The notification means 10 can notify the timing of adding the dialysis powder based on the liquid level of the dialysis stock solution detected by the liquid level detection means 9, and can be used to output a sound, a sound effect, etc. It consists of lights. That is, when the liquid level detected by the liquid level detecting means 9 is lower than a predetermined height and the stock solution for dialysis is predicted to be insufficient, the notifying means 10 notifies the additional powder for dialysis. An undiluted dialysis solution can be additionally prepared by adding it to a worker such as a medical worker and further dissolving it.

次に、本実施形態に係る溶解装置１による溶解のための動作について説明する。
先ず、透析治療前（治療前日の夜等）において、図６に示すように、第２溶解槽３に所定量（準備溶解袋数）の透析用粉末剤を投入して収容させておく。そして、バルブＶ１、Ｖ２を開状態としつつバルブＶ３〜Ｖ６を閉状態とすることにより、給水源から第１溶解槽２に給水するとともに、ポンプＰ１を駆動させることにより、供給された水を循環させる。 Next, the operation | movement for melt | dissolution by the melt | dissolution apparatus 1 which concerns on this embodiment is demonstrated.
First, before dialysis treatment (the night before the treatment, etc.), as shown in FIG. 6, a predetermined amount (the number of preparation dissolution bags) of dialysis powder is put into and stored in the second dissolution tank 3. Then, the valves V3 and V6 are closed while the valves V1 and V2 are opened, so that water is supplied to the first dissolution tank 2 from the water supply source and the supplied water is circulated by driving the pump P1. Let

その後、図７に示すように、バルブＶ１、Ｖ３、Ｖ４を開状態としつつバルブＶ２、Ｖ５、Ｖ６を閉状態とし、給水源からの給水及びポンプＰ１の駆動を継続して行わせることにより、第１溶解槽２内の水を第２溶解槽３に送り込む。これにより、予め第２溶解槽３内に収容された透析用粉末剤に水が送り込まれて溶解するとともに、その溶解液（透析用原液となる過程の溶液）がオーバーフローラインＬ５を介して第１溶解槽２に送り込まれることとなる。   After that, as shown in FIG. 7, the valves V2, V5, and V6 are closed while the valves V1, V3, and V4 are opened, and the water supply from the water supply source and the drive of the pump P1 are continuously performed. Water in the first dissolution tank 2 is fed into the second dissolution tank 3. As a result, water is fed into the dialysis powder previously accommodated in the second dissolution tank 3 and dissolved, and the solution (solution in the process of becoming a dialysis stock solution) passes through the overflow line L5 to the first. It will be sent to the dissolution tank 2.

そして、所定量の給水が行われると、図８に示すように、バルブＶ３、Ｖ４を開状態としつつバルブＶ１、Ｖ２、Ｖ５、Ｖ６を閉状態とし、給水源からの給水を停止する一方、ポンプＰ１の駆動を継続して行わせることにより、第１溶解槽２と第２溶解槽３との間で透析用原液を循環させる。これにより、作製した透析用原液を攪拌することができ、均一な濃度の透析用原液を得ることができる。   When a predetermined amount of water is supplied, as shown in FIG. 8, the valves V1, V2, V5, V6 are closed while the valves V3, V4 are open, and the water supply from the water supply source is stopped. By continuously driving the pump P1, the stock solution for dialysis is circulated between the first dissolution tank 2 and the second dissolution tank 3. As a result, the prepared dialysis stock solution can be stirred, and a dialysis stock solution having a uniform concentration can be obtained.

上記のように第１溶解槽２及び第２溶解槽３のそれぞれに透析用原液が収容された状態において、図９に示すように、バルブＶ５を開状態としつつバルブＶ１〜Ｖ４、Ｖ６を閉状態とし、ポンプＰ１及びポンプＰ２を駆動させることにより、送液ラインＬ３を介して第１溶解槽２内の透析用原液を透析液供給装置Ｂに送液することができ、所定濃度の透析液を各透析装置Ａに供給させて透析治療を行わせることができる。   In the state where the first lysis tank 2 and the second lysis tank 3 are accommodated in the first dissolution tank 2 and the second dissolution tank 3 as described above, as shown in FIG. 9, the valves V1 to V4 and V6 are closed while the valve V5 is opened. When the pump P1 and the pump P2 are driven, the dialysis stock solution in the first dissolution tank 2 can be sent to the dialysate supply device B via the feed line L3. Can be supplied to each dialysis apparatus A to perform dialysis treatment.

その後、液位検出手段９にて第１溶解槽２内の透析用原液の液位が所定高さに達すると、報知手段１０にて追加投入のための報知がなされる。この場合、図１０に示すように、バルブＶ１、Ｖ２、Ｖ４、Ｖ６を開状態としつつバルブＶ３、Ｖ５を閉状態とし、給水源からの給水を行わせる一方、ポンプＰ２の駆動を継続して行わせることにより、第１溶解槽２に代えて第２溶解槽３内の透析用原液を透析液供給装置Ｂに送液する。   After that, when the liquid level of the dialysis stock solution in the first dissolution tank 2 reaches a predetermined height by the liquid level detection means 9, a notification for additional charging is made by the notification means 10. In this case, as shown in FIG. 10, the valves V1, V2, V4, and V6 are opened, the valves V3 and V5 are closed, and water is supplied from the water supply source, while the pump P2 is continuously driven. As a result, the dialysis stock solution in the second dissolution tank 3 is sent to the dialysate supply apparatus B instead of the first dissolution tank 2.

しかして、第１溶解槽２内に所定量（追加投入袋数）の追加の透析用粉末剤を投入させることができ、その投入された透析用粉末剤が給水源からの給水によって溶解されることとなる。なお、ポンプＰ１を駆動させることにより、透析用原液となる過程の溶液を循環させることができる。これにより、第１溶解槽２に代えて第２溶解槽３からの透析用原液の送液が引き続き行われるとともに、第１溶解槽２において追加の透析用粉末剤を投入させて溶解することができる。   Thus, a predetermined amount (additional number of additional bags) of additional dialysis powder can be charged into the first dissolution tank 2, and the charged dialysis powder is dissolved by water supplied from a water supply source. It will be. In addition, by driving the pump P1, it is possible to circulate the solution in the process of becoming a dialysis stock solution. As a result, the dialysis stock solution is continuously fed from the second dissolution tank 3 instead of the first dissolution tank 2, and the additional powder for dialysis is added and dissolved in the first dissolution tank 2. it can.

そして、所定量の給水が行われると、図１１に示すように、バルブＶ２、Ｖ４、Ｖ６を開状態としつつバルブＶ１、Ｖ３、Ｖ５を閉状態とし、給水源からの給水を停止する一方、ポンプＰ１、Ｐ２の駆動を継続して行わせることにより、第２溶解槽３から透析用原液の送液を引き続き行わせるとともに、第１溶解槽２内の透析用原液を循環させて攪拌し、均一な濃度の透析用原液を得ることができる。   Then, when a predetermined amount of water is supplied, as shown in FIG. 11, the valves V1, V3, V5 are closed while the valves V2, V4, V6 are opened, and the water supply from the water supply source is stopped, By continuously driving the pumps P1 and P2, the dialysis stock solution is continuously fed from the second dissolution tank 3, and the dialysis stock solution in the first dissolution tank 2 is circulated and stirred. A dialysis stock solution having a uniform concentration can be obtained.

上記のように第１溶解槽２に透析用原液が収容された状態において、図１２に示すように、バルブＶ２〜Ｖ５を開状態としつつバルブＶ１、Ｖ６を閉状態とし、ポンプＰ１及びポンプＰ２を駆動させることにより、送液ラインＬ３を介して第１溶解槽２内の透析用原液を透析液供給装置Ｂに送液することができ、所定濃度の透析液を各透析装置Ａに供給させて透析治療を行わせることができる。このとき、第１溶解槽２内の透析用原液の一部は、第２溶解槽３内に移送され、オーバーフローラインＬ５にてオーバーフローする状態まで透析用原液が送り込まれることとなる。   In the state in which the dialysis stock solution is stored in the first dissolution tank 2 as described above, as shown in FIG. 12, the valves V1 and V6 are closed while the valves V2 to V5 are opened, and the pumps P1 and P2 , The dialysis stock solution in the first dissolution tank 2 can be sent to the dialysate supply device B via the feed line L3, and the dialysate having a predetermined concentration can be supplied to each dialyzer A. Dialysis treatment can be performed. At this time, a part of the dialysis stock solution in the first dissolution tank 2 is transferred into the second dissolution tank 3, and the dialysis stock solution is sent to the overflow state in the overflow line L5.

その後、図９に示すように、バルブＶ５を開状態としつつバルブＶ１〜Ｖ４、Ｖ６を閉状態とし、ポンプＰ１及びポンプＰ２を駆動させることにより、送液ラインＬ３を介して第１溶解槽２内の透析用原液を透析液供給装置Ｂに送液することができ、所定濃度の透析液を各透析装置Ａに供給させて透析治療を行わせることができる。これにより、第１溶解槽２にて追加溶解された透析用原液を透析液供給装置Ｂに供給することができるので、各透析装置Ａによる透析治療を継続して行わせることができる。   Thereafter, as shown in FIG. 9, the valves V1 to V4 and V6 are closed while the valve V5 is opened, and the pump P1 and the pump P2 are driven, whereby the first dissolution tank 2 is connected via the liquid feed line L3. The dialysis stock solution can be sent to the dialysate supply device B, and a dialysate having a predetermined concentration can be supplied to each dialyzer A to perform dialysis treatment. Thereby, since the dialysis stock solution additionally dissolved in the first dissolution tank 2 can be supplied to the dialysate supply device B, dialysis treatment by each dialyzer A can be continuously performed.

このように、本実施形態に係る溶解装置１は、透析治療中、患者に透析治療を施すための複数の透析装置Ａ側に第１溶解槽２及び第２溶解槽３の透析用原液を送液するのに伴って、追加の透析用粉末剤を所定量毎（本実施形態においては透析用粉末剤を収容する袋単位（袋数））に投入させて溶解し得るものであり、所謂バッチ式と称される溶解装置から成るものとされている。   Thus, the dissolution apparatus 1 according to the present embodiment sends the dialysis stock solutions in the first dissolution tank 2 and the second dissolution tank 3 to the plurality of dialysis apparatuses A for performing dialysis treatment on the patient during dialysis treatment. As the liquid is added, an additional powder for dialysis can be poured into a predetermined amount (in this embodiment, a bag unit (number of bags) containing the powder for dialysis) and dissolved, so-called batch. It is supposed to consist of a melting device called a formula.

ここで、本実施形態に係る溶解装置１の筐体部には、図５に示すように、入力手段４と、記憶手段５と、設定手段６と、予測手段７と、表示手段８とを有して構成されている。入力手段４は、操作者が入力操作可能な操作スイッチやタッチパネル等により構成されたもので、本実施形態においては、透析治療において必要とされる透析用粉末剤の総量を入力し得るものとされている。   Here, as shown in FIG. 5, an input unit 4, a storage unit 5, a setting unit 6, a prediction unit 7, and a display unit 8 are provided in the casing of the melting apparatus 1 according to the present embodiment. It is configured. The input means 4 is configured by an operation switch or a touch panel that can be input by the operator. In this embodiment, the input means 4 can input the total amount of powder for dialysis required in dialysis treatment. ing.

表示手段８は、溶解作業に関する種々表示を行い得る液晶モニタ等にて構成されるもので、本実施形態においては、入力手段４と表示手段８とを兼用するタッチパネルにて構成されている。なお、入力手段４と表示手段８とを兼用するタッチパネルとするものの他、入力手段４と表示手段８とを別個に具備するものとしてもよい。   The display means 8 is composed of a liquid crystal monitor or the like that can perform various displays relating to the melting operation. In the present embodiment, the display means 8 is composed of a touch panel that serves as both the input means 4 and the display means 8. In addition, it is good also as what has the input means 4 and the display means 8 separately besides what is used as the touch panel which serves as the input means 4 and the display means 8.

記憶手段５は、過去の透析治療中における追加の透析用粉末剤を投入したタイミングを実績投入タイミングとして記憶し得るもので、本実施形態においては、病院等の医療施設における患者の治療日程に対応した特定の治療日毎（具体的には曜日毎）に実績投入タイミングを記憶するよう構成されている。すなわち、透析患者は、通常、決まった曜日（例えば月曜日、水曜日及び金曜日）に透析治療を受けることから、医療従事者も曜日毎に決まった作業を行うこととなる。したがって、曜日（患者の治療日程に対応した特定の治療日毎）によって透析用原液や透析液の消費量及び流量がほぼ一定となるので、曜日毎に実績投入タイミングを記憶すれば追加の透析用粉末剤を投入するタイミングを精度よく予測することができる。   The storage means 5 can store the timing when the additional powder for dialysis during the past dialysis treatment is input as the actual input timing. In this embodiment, the storage means 5 corresponds to the treatment schedule of the patient in a medical facility such as a hospital. The result input timing is stored every specific treatment day (specifically, every day of the week). That is, since a dialysis patient usually receives dialysis treatment on a fixed day of the week (for example, Monday, Wednesday, and Friday), a medical worker also performs a fixed operation for each day of the week. Therefore, the consumption and flow rate of the dialysis solution and dialysis solution are almost constant depending on the day of the week (every specific treatment day corresponding to the patient's treatment schedule). It is possible to accurately predict the timing of adding the agent.

設定手段６は、入力手段４にて入力された透析用粉末剤の総量に基づいて、透析用粉末剤を追加投入すべき追加回数と、各追加投入タイミングで投入すべき透析用粉末剤の追加量とを自動的に設定し得るものである。例えば、表示手段８において、図１３に示すようなメニュー画面で特定の曜日（例えば月曜日）を選択し、その日に必要とされる透析用粉末剤の総量を入力すると、準備溶解量（治療前に予め溶解する袋数）と、透析用粉末剤を追加する回数（追加回数）と、各追加タイミングで投入すべき透析用粉末剤の投入量（追加時の袋数）とを自動的に割り振って設定し、図１４に示すように、表示手段８にて表示させるよう構成されている。   The setting means 6 adds the number of additional dialysis powders to be added based on the total amount of the dialysis powder input by the input means 4 and the addition of the dialysis powder to be added at each additional injection timing. The amount can be set automatically. For example, when a specific day of the week (for example, Monday) is selected on the menu screen as shown in FIG. 13 on the display means 8 and the total amount of powder for dialysis required on that day is input, The number of dialysis powders to be added (number of additions) and the amount of dialysis powder to be added at each additional timing (number of bags at the time of addition) are automatically allocated. As shown in FIG. 14, it is configured to display on the display means 8.

予測手段７は、記憶手段５で記憶された実績投入タイミング（本実施形態においては時刻）に基づいて、これから行われる透析治療中における追加の透析用粉末剤を投入するタイミングを予測投入タイミングとして予測し得るものである。具体的には、記憶手段５で記憶された実績投入タイミングのうち直近のもの（これから透析治療する日が月曜日であれば、先週の月曜日のもの）が予測投入タイミングとされるとともに、その後の曜日毎の透析治療日において、実績投入タイミングを順次上書き保存し、記憶手段５で記憶される実績投入タイミングを透析治療日毎にアップデート（記憶した情報を更新）するようになっている。   The predicting means 7 predicts the timing of adding an additional powder for dialysis during the dialysis treatment to be performed as the predicted input timing based on the result input timing (time in the present embodiment) stored in the storage means 5. It is possible. Specifically, the most recent result input timing stored in the storage means 5 (if the day on which dialysis treatment is to be performed from now on is Monday, the previous Monday) is set as the predicted input timing, and the subsequent day of the week In each dialysis treatment date, the actual input timing is sequentially overwritten and saved, and the actual input timing stored in the storage means 5 is updated (updates the stored information) for each dialysis treatment date.

また、予測手段７による予測投入タイミングの予測方法として、上記のものに限らず、例えば過去の透析治療中における複数の実績投入タイミングを記憶手段５で記憶しておき、その平均値等を演算して予測投入タイミングとするもの、或いは曜日毎の透析用原液の消費パターン（消費傾向）が一定となったことを条件として、その消費パターンに基づいて予測投入タイミングを予測するもの等であってもよい。   In addition, the prediction method of the prediction input timing by the prediction means 7 is not limited to the above, but for example, a plurality of actual input timings during the past dialysis treatment are stored in the storage means 5 and an average value thereof is calculated. Even if the estimated input timing is used, or if the consumption pattern (consumption trend) of the dialysis stock solution for each day of the week is constant, the predicted input timing is predicted based on the consumption pattern, etc. Good.

なお、最初に本装置を使用する場合や試運転を行う場合等、記憶手段５にて実績投入タイミングが記憶されていない場合、例えば１クール（特定の医療施設において１日で行われる治療の単位）を５時間とし、そのうち準備作業に３０分、返血作業に３０分及び液置換に３０分それぞれかかることを想定し、クール毎の血液治療の開始時刻及び患者の数（床数）等を考慮すれば、実績投入タイミングが記憶されていなくても透析用粉末剤の投入タイミングを予測することができる。   In addition, when the results input timing is not stored in the storage means 5, such as when the apparatus is used for the first time or when a trial operation is performed, for example, one course (unit of treatment performed in one day at a specific medical facility) Assuming that it takes 30 minutes for preparation work, 30 minutes for blood return work, and 30 minutes for liquid replacement, considering the start time of blood treatment and the number of patients (number of beds) By doing so, it is possible to predict the charging timing of the powder for dialysis even if the actual charging timing is not stored.

また、溶解工程において、その日の透析用粉末剤の総量（袋数）が一時的に増加する場合、袋数１つにつき患者が１人変更になったと想定し、それまでの実績データに透析用原液の消費速度を対応させて透析用原液の消費傾向を作成し、透析用粉末剤の投入タイミングを予測してもよく、透析用粉末剤の総量（袋数）が恒久的に増加する場合、袋数１つにつき患者が１人変更になったと想定し、透析用原液の消費速度を対応させて透析用原液の消費傾向を作成し、透析用粉末剤の投入タイミングを予測してもよい。   Also, in the dissolution process, if the total amount of dialysis powder for the day (number of bags) temporarily increases, it is assumed that one patient has been changed per bag, and the actual data up to that point is for dialysis. The consumption rate of the stock solution can be adjusted to create a consumption trend for the stock solution for dialysis, and the timing of dialysis powder injection can be predicted. If the total amount of dialysis powder (the number of bags) increases permanently, Assuming that one patient is changed per bag number, the consumption rate of the dialysis undiluted solution may be created corresponding to the consumption rate of the dialysis undiluted solution, and the injection timing of the dialysis powder may be predicted.

表示手段８は、上述の如く溶解作業に関する種々表示を行い得るもので、特に本実施形態においては、図１４に示すように、予測手段７で予測された予測投入タイミングを表示し得るよう構成されている。また、本実施形態に係る表示手段８は、同図に示すように、予測手段７で予測された予測投入タイミングと併せて設定手段６で設定された追加回数及び追加量が表示されている。しかるに、本実施形態においては、表示手段８で表示される予測投入タイミングが「時刻」とされているが、投入タイミングが分かる他の形態であってもよく、例えば溶解開始時からの経過時間を予測投入タイミングとして表示するようにしてもよい。   The display means 8 can perform various displays relating to the melting operation as described above. In particular, in the present embodiment, as shown in FIG. 14, the display means 8 is configured to display the predicted charging timing predicted by the prediction means 7. ing. Further, the display unit 8 according to the present embodiment displays the number of additions and the addition amount set by the setting unit 6 together with the predicted insertion timing predicted by the prediction unit 7 as shown in FIG. However, in the present embodiment, the predicted charging timing displayed on the display unit 8 is “time”, but other modes in which the charging timing is known may be used. For example, the elapsed time from the start of melting is calculated. You may make it display as prediction insertion timing.

さらに、本実施形態に係る予測手段７は、報知手段１０で報知された追加投入タイミングに基づいて次回以降の予測投入タイミングを修正し、その修正された予測投入タイミングを表示手段８にて表示させ得るよう構成されている。例えば、図１７に示すように、報知手段１０で報知された実際の追加投入タイミングと、そのときの予測手段７で予測された予測投入タイミングとの時間差（Δｔ）を算出し（Ｓ１）、次回以降の予測投入タイミングを時間差（Δｔ）だけずらす（Ｓ２）ことにより、予測投入タイミングを逐次修正し、その修正された予測投入タイミングが表示手段８にて表示されることとなる。   Furthermore, the prediction means 7 according to the present embodiment corrects the predicted injection timing for the next and subsequent times based on the additional injection timing notified by the notification means 10 and causes the display means 8 to display the corrected predicted injection timing. Configured to get. For example, as shown in FIG. 17, the time difference (Δt) between the actual additional insertion timing notified by the notification means 10 and the predicted insertion timing predicted by the prediction means 7 at that time is calculated (S1), By shifting the predicted input timing thereafter by the time difference (Δt) (S2), the predicted input timing is sequentially corrected, and the corrected predicted input timing is displayed on the display means 8.

またさらに、本実施形態においては、設定手段６で設定された追加回数又は追加量を任意に変更可能とされるとともに、予測手段７は、当該変更に対応して予測投入タイミングを修正し、その修正された予測投入タイミングを表示手段８にて表示させ得るよう構成されている。例えば、図１５に示すように、１回目における透析用粉末剤の追加量を１０袋から８袋に変更した場合、その分、最終回（同図においては４回目）における追加量を修正して表示するとともに、２回目以降の予測投入タイミングをずらして表示させる。また、図１６に示すように、１回あたりの透析液粉末剤の追加量を８袋に減らし、追加回数を５回に増加させることも可能とされている。   Furthermore, in the present embodiment, the number of additions or the amount of addition set by the setting unit 6 can be arbitrarily changed, and the prediction unit 7 corrects the predicted injection timing in response to the change, and The corrected predicted input timing can be displayed on the display means 8. For example, as shown in FIG. 15, when the additional amount of the powder for dialysis at the first time is changed from 10 bags to 8 bags, the additional amount at the final time (the fourth time in the figure) is corrected accordingly. In addition to the display, the second and subsequent prediction insertion timings are shifted and displayed. In addition, as shown in FIG. 16, it is possible to reduce the additional amount of dialysate powder per time to 8 bags and increase the number of additions to 5.

このように、追加量（袋数）を変更する場合、図１９に示すように、記憶手段５にて過去の透析治療における透析用原液の経時的な消費傾向を記憶しておく。そして、例えば図１８に示すように、変更される袋数から生成される透析用原液の量を算出し（Ｓ１）、その透析用原液が消費される時刻を記憶手段５に記憶されたデータ（透析用原液の経時的な消費傾向）から予測（Ｓ２）した後、袋数が変更された以降の予測投入タイミングを修正（Ｓ３）することにより、その修正された予測投入タイミングが表示手段８にて表示されることとなる。   As described above, when the additional amount (the number of bags) is changed, as shown in FIG. 19, the storage means 5 stores the time-dependent consumption trend of the dialysis stock solution in the past dialysis treatment. Then, for example, as shown in FIG. 18, the amount of the dialysis stock solution generated from the changed number of bags is calculated (S1), and the time when the dialysis stock solution is consumed is stored in the storage means 5 ( After the prediction (S2) based on the dialysis stock solution consumption trend), the predicted injection timing after the change in the number of bags is corrected (S3). Will be displayed.

上記実施形態によれば、過去の透析治療中における追加の透析用粉末剤を投入したタイミングを実績投入タイミングとして記憶し得る記憶手段５と、記憶手段５で記憶された実績投入タイミングに基づいて、これから行われる透析治療中における追加の透析用粉末剤を投入するタイミングを予測投入タイミングとして予測し得る予測手段７と、予測手段７で予測された予測投入タイミングを表示し得る表示手段８とを具備したので、追加の透析用粉末剤の投入タイミングを作業者に対して予め把握させることができる。   According to the above-described embodiment, based on the storage unit 5 that can store the timing of adding the additional dialysis powder during the past dialysis treatment as the actual input timing, and the actual input timing stored in the storage unit 5, Predicting means 7 capable of predicting the timing of adding an additional dialysis powder during dialysis treatment to be performed as predicted charging timing, and display means 8 capable of displaying the predicted charging timing predicted by the predicting means 7 Therefore, it is possible to make the operator know in advance the timing of adding the additional dialysis powder.

また、透析治療において必要とされる透析用粉末剤の総量を入力し得るとともに、入力された透析用粉末剤の総量に基づいて、透析用粉末剤を追加投入すべき追加回数と、各追加投入タイミングで投入すべき透析用粉末剤の追加量とを設定し得る設定手段６を具備し、表示手段８は、予測投入タイミングと併せて設定手段６で設定された追加回数及び追加量を表示可能とされたので、追加回数及び追加量と併せて追加の透析用粉末剤の投入タイミングを作業者に対して予め把握させることができる。   In addition, the total amount of dialysis powder required for dialysis treatment can be entered, and the number of additional dialysis powders to be added based on the total amount of dialysis powder entered and each additional dose A setting unit 6 that can set an additional amount of the dialysis powder to be charged at the timing is provided, and the display unit 8 can display the number of additions and the additional amount set by the setting unit 6 together with the predicted charging timing. Therefore, it is possible to make the operator know in advance the timing of adding the additional powder for dialysis together with the number of additions and the additional amount.

さらに、設定手段６で設定された追加回数又は追加量を任意に変更可能とされるとともに、予測手段７は、当該変更に対応して予測投入タイミングを修正し、その修正された予測投入タイミングを表示手段８にて表示させ得るので、追加回数又は追加量の変更に伴う予測投入タイミングのずれを自動的に修正して表示させることができる。   Furthermore, the number of additions or addition amount set by the setting means 6 can be arbitrarily changed, and the prediction means 7 corrects the predicted insertion timing in response to the change, and the corrected predicted insertion timing is changed. Since it can be displayed on the display means 8, it is possible to automatically correct and display the shift in the predicted insertion timing accompanying the change in the number of additions or the addition amount.

またさらに、溶解槽（２、３）内に収容された透析用原液の液位を連続的且つリアルタイムに検出可能な液位検出手段９と、液位検出手段９で検出された透析用原液の液位に基づいて透析用粉末剤の追加投入タイミングを報知し得る報知手段１０とを具備するとともに、予測手段７は、報知手段１０で報知された追加投入タイミングに基づいて次回以降の予測投入タイミングを修正し、その修正された予測投入タイミングを表示手段８にて表示させ得るので、予測投入タイミングが報知手段１０で報知された実際の追加投入タイミングに対してずれた場合、そのずれを修正して表示させることができ、予測投入タイミングを精度よく予測することができる。   Furthermore, the liquid level detection means 9 capable of detecting the liquid level of the dialysis stock solution stored in the dissolution tank (2, 3) continuously and in real time, and the dialysis stock solution detected by the liquid level detection means 9 And a notifying means 10 capable of notifying the additional charging timing of the dialysis powder based on the liquid level, and the predicting means 7 is based on the additional charging timing notified by the notifying means 10 for the next and subsequent predicted charging timings. And the corrected predicted insertion timing can be displayed on the display means 8, so if the predicted insertion timing deviates from the actual additional injection timing notified by the notification means 10, the deviation is corrected. And the predicted input timing can be accurately predicted.

特に、本実施形態に係る記憶手段５は、医療施設における患者の治療日程（治療サイクル）に対応した特定の治療日毎（本実施形態においては曜日毎）に実績投入タイミングを記憶するとともに、予測手段７は、当該特定の治療日毎の予測投入タイミングを予測して表示手段で表示させ得るので、患者の治療日程が予め決まっている透析治療において、予測投入タイミングをより精度よく予測することができる。   In particular, the storage unit 5 according to the present embodiment stores the actual input timing for each specific treatment day (in this embodiment, every day of the week) corresponding to the treatment schedule (treatment cycle) of the patient in the medical facility, and also the prediction unit. 7 can predict the predicted input timing for each specific treatment day and display it on the display means, so that the predicted input timing can be predicted with higher accuracy in dialysis treatment in which the patient's treatment schedule is determined in advance.

さらに、表示手段８で表示される予測投入タイミングは、時刻又は溶解開始時からの経過時間とされるので、追加の透析用粉末剤の投入タイミングを作業者に対してより正確に把握させることができる。なお、本実施形態においては、予測投入タイミングと併せて設定手段６で設定された追加回数及び追加量を表として表示しているので、追加タイミングを視覚的に把握させることができる。これらの表示は、表以外、グラフ等として表示されるようにしてもよい。   Furthermore, since the predicted charging timing displayed on the display means 8 is the time or the elapsed time from the start of dissolution, it is possible to make the worker know the charging timing of the additional dialysis powder more accurately. it can. In the present embodiment, since the number of additions and the addition amount set by the setting unit 6 are displayed as a table together with the predicted insertion timing, the addition timing can be visually grasped. These displays may be displayed as a graph or the like other than the table.

以上、本実施形態について説明したが、本発明はこれに限定されず、例えば図２０に示すように、所定量の透析用粉末剤を収容する収容手段Ｍと、収容手段Ｍ内の透析用粉末剤を所定量ずつ溶解槽Ｔに供給し得るフィーダＦと、収容手段Ｍ内の透析用粉末の重量を経時的に計測し得る重量計Ｓとを有した溶解装置に適用してもよい。この場合、追加の透析用粉末剤は、収容手段Ｍに対して投入されることとなり、その実績投入タイミングが記憶されるとともに予測投入タイミングを予測して表示手段８にて表示させることができる。   Although the present embodiment has been described above, the present invention is not limited to this. For example, as shown in FIG. 20, a storage unit M that stores a predetermined amount of dialysis powder, and a dialysis powder in the storage unit M You may apply to the dissolving apparatus which has the feeder F which can supply a chemical | medical agent to the dissolution tank T by predetermined amount, and the weight meter S which can measure the weight of the powder for dialysis in the accommodating means M with time. In this case, the additional powder for dialysis is charged into the storage means M, the actual charging timing is stored, and the predicted charging timing can be predicted and displayed on the display means 8.

さらに、本実施形態に係る溶解装置１は、透析用粉末剤を投入して溶解するための第１溶解槽２及び第２溶解槽３を具備しているが、１つの溶解槽を具備したもの或いは３つ以上の溶解槽を具備したものに適用してもよい。また、記憶手段５は、曜日毎に実績投入タイミングを記憶し、曜日毎に表示手段８にて予測投入タイミングを表示しているが、医療施設における患者の治療日程に対応した特定の治療日毎であれば、他の日程であってもよい。   Furthermore, the dissolution apparatus 1 according to the present embodiment includes the first dissolution tank 2 and the second dissolution tank 3 for charging and dissolving the dialysis powder, but includes one dissolution tank. Or you may apply to what comprised the 3 or more dissolution tank. The storage unit 5 stores the actual input timing for each day of the week, and the predicted input timing is displayed on the display unit 8 for each day of the week, but for each specific treatment day corresponding to the treatment schedule of the patient in the medical facility. Other schedules may be used if necessary.

過去の透析治療中における追加の透析用粉末剤を投入したタイミングを実績投入タイミングとして記憶し得る記憶手段と、記憶手段で記憶された実績投入タイミングに基づいて、これから行われる透析治療中における追加の透析用粉末剤を投入するタイミングを予測投入タイミングとして予測し得る予測手段と、予測手段で予測された予測投入タイミングを表示し得る表示手段とを具備した溶解装置であれば、外観形状が異なるもの或いは他の機能が付加されたもの等にも適用することができる。   The storage means that can store the timing of adding the additional dialysis powder during the past dialysis treatment as the actual input timing, and the additional time during the dialysis treatment to be performed based on the actual input timing stored in the storage means As long as the dissolution apparatus has a predicting means that can predict the timing of charging the dialysis powder as the predicted charging timing and a display means that can display the predicted charging timing predicted by the predicting means, the external shape is different. Alternatively, the present invention can also be applied to those with other functions added.

１ 溶解装置
２ 第１溶解槽
３ 第２溶解槽
４ 入力手段
５ 記憶手段
６ 設定手段
７ 予測手段
８ 表示手段
９ 液位検出手段
１０ 報知手段
Ｌ１ 給水ライン
Ｌ２ 接続ライン
Ｌ３ 送液ライン
Ｌ４ 接続ライン
Ｌ５ オーバーフローライン
Ａ 透析装置
Ｂ 透析液供給装置 DESCRIPTION OF SYMBOLS 1 Dissolution apparatus 2 1st dissolution tank 3 2nd dissolution tank 4 Input means 5 Storage means 6 Setting means 7 Prediction means 8 Display means 9 Liquid level detection means 10 Notification means L1 Water supply line L2 Connection line L3 Liquid supply line L4 Connection line L5 Overflow line A Dialysis machine B Dialysate supply device

Claims (6)

透析用粉末剤を溶解して透析用原液を得るとともに、その溶解された透析用原液を所定量収容し得る溶解槽を具備し、透析治療中、患者に透析治療を施すための複数の透析装置側に前記溶解槽の透析用原液を送液するのに伴って、追加の透析用粉末剤を所定量毎に投入させて溶解し得る溶解装置において、
過去の透析治療中における追加の透析用粉末剤を投入したタイミングを実績投入タイミングとして記憶し得る記憶手段と、
前記記憶手段で記憶された実績投入タイミングに基づいて、これから行われる透析治療中における追加の透析用粉末剤を投入するタイミングを予測投入タイミングとして予測し得る予測手段と、
前記予測手段で予測された予測投入タイミングを表示し得る表示手段と、
を具備したことを特徴とする溶解装置。 A plurality of dialysis apparatuses for dissolving a dialysis powder to obtain a dialysis stock solution and having a dissolution tank capable of storing a predetermined amount of the dissolved dialysis stock solution and performing dialysis treatment on a patient during dialysis treatment In the dissolution apparatus that can be added to the dialysis stock solution in the dissolution tank on the side and dissolved by adding an additional dialysis powder every predetermined amount,
Storage means capable of storing the timing when the additional powder for dialysis during the past dialysis treatment is input as the actual input timing;
Prediction means that can predict the timing of adding an additional dialysis powder during dialysis treatment to be performed as the predicted charging timing based on the actual charging timing stored in the storage means;
Display means capable of displaying the predicted input timing predicted by the prediction means;
A melting apparatus comprising: 透析治療において必要とされる透析用粉末剤の総量を入力し得るとともに、入力された透析用粉末剤の総量に基づいて、透析用粉末剤を追加投入すべき追加回数と、各追加投入タイミングで投入すべき透析用粉末剤の追加量とを設定し得る設定手段を具備し、前記表示手段は、前記予測投入タイミングと併せて前記設定手段で設定された追加回数及び追加量を表示可能とされたことを特徴とする請求項１記載の溶解装置。   The total amount of dialysis powder required in dialysis treatment can be entered, and the number of additional dialysis powders to be added and the timing of each addition based on the total amount of dialysis powder entered. A setting means capable of setting an additional amount of the dialysis powder to be charged, and the display means can display the number of additions and the additional amount set by the setting means together with the predicted charging timing. The melting apparatus according to claim 1, wherein 前記設定手段で設定された追加回数又は追加量を任意に変更可能とされるとともに、前記予測手段は、当該変更に対応して前記予測投入タイミングを修正し、その修正された予測投入タイミングを前記表示手段にて表示させ得ることを特徴とする請求項２記載の溶解装置。   The number of additions or addition amount set by the setting means can be arbitrarily changed, and the prediction means corrects the predicted insertion timing in response to the change, and the corrected predicted insertion timing is The melting apparatus according to claim 2, wherein the melting device can be displayed by a display means. 前記溶解槽内に収容された透析用原液の液位を連続的且つリアルタイムに検出可能な液位検出手段と、
前記液位検出手段で検出された透析用原液の液位に基づいて前記透析用粉末剤の追加投入タイミングを報知し得る報知手段と、
を具備するとともに、前記予測手段は、前記報知手段で報知された追加投入タイミングに基づいて次回以降の前記予測投入タイミングを修正し、その修正された予測投入タイミングを前記表示手段にて表示させ得ることを特徴とする請求項２又は３記載の溶解装置。 A liquid level detection means capable of continuously and in real time detecting the liquid level of the stock solution for dialysis accommodated in the dissolution tank;
Informing means capable of informing the additional charging timing of the dialysis powder based on the liquid level of the dialysis stock solution detected by the liquid level detecting means,
And the prediction means can correct the predicted injection timing for the next and subsequent times based on the additional injection timing notified by the notification means, and can display the corrected predicted injection timing on the display means. The dissolution apparatus according to claim 2 or 3, wherein 前記記憶手段は、医療施設における患者の治療日程に対応した特定の治療日毎に前記実績投入タイミングを記憶するとともに、前記予測手段は、当該特定の治療日毎の予測投入タイミングを予測して前記表示手段で表示させ得ることを特徴とする請求項１〜４の何れか１つに記載の溶解装置。   The storage means stores the actual input timing for each specific treatment day corresponding to a treatment schedule of a patient in a medical facility, and the prediction means predicts a predicted input timing for each specific treatment day and displays the display means The dissolution apparatus according to any one of claims 1 to 4, wherein the dissolution apparatus is capable of being displayed. 前記表示手段で表示される予測投入タイミングは、時刻又は溶解開始時からの経過時間とされることを特徴とする請求項１〜５の何れか１つに記載の溶解装置。   The melting apparatus according to claim 1, wherein the predicted charging timing displayed by the display means is a time or an elapsed time from the start of melting.
JP2017054678A 2017-03-21 2017-03-21 Melting device Active JP6831279B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2017054678A JP6831279B2 (en) 2017-03-21 2017-03-21 Melting device
CN201810235876.2A CN108619925B (en) 2017-03-21 2018-03-21 Dissolving device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2017054678A JP6831279B2 (en) 2017-03-21 2017-03-21 Melting device

Publications (2)

Publication Number Publication Date
JP2018153557A true JP2018153557A (en) 2018-10-04
JP6831279B2 JP6831279B2 (en) 2021-02-17

Family

ID=63696158

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017054678A Active JP6831279B2 (en) 2017-03-21 2017-03-21 Melting device

Country Status (2)

Country Link
JP (1) JP6831279B2 (en)
CN (1) CN108619925B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020262175A1 (en) * 2019-06-26 2020-12-30 日機装株式会社 Blood purification system and raw liquid preparation determination device

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293845A (en) * 1980-04-17 1981-10-06 Villa Real Antony Euclid C Electronic multi-patient medication-time-intake programmer and alarm system
DE3335301C2 (en) * 1983-06-25 1985-05-02 Udo 8500 Nürnberg Simon Drug container
CN2114653U (en) * 1990-10-27 1992-09-02 中国人民解放军第一四八医院 Full automatic liquid matching machine
JP2001232173A (en) * 2000-02-28 2001-08-28 Fuji Photo Film Co Ltd Treating agent dissolving device
DE102005025516A1 (en) * 2005-06-03 2006-12-07 Fresenius Medical Care Deutschland Gmbh Medical treatment system with a device for providing patient-related data
US20070038889A1 (en) * 2005-08-11 2007-02-15 Wiggins Robert D Methods and systems to access process control log information associated with process control systems
JP4904077B2 (en) * 2006-04-26 2012-03-28 日機装株式会社 Blood purification equipment
CN101342389B (en) * 2008-09-03 2010-06-02 荣维淳 Full-automatic liquid preparation machine
DE102012004886A1 (en) * 2012-03-10 2013-09-12 Manfred Völker Mixing device for the production of ready-to-use medical rinsing solutions, in particular for the hemodialysis concentrates
JP6424031B2 (en) * 2014-07-15 2018-11-14 日機装株式会社 Melting equipment
JP6435127B2 (en) * 2014-07-15 2018-12-05 日機装株式会社 Melting equipment
ES2622351T3 (en) * 2014-10-15 2017-07-06 Dunschat, Christoph Dialysis concentrate manufacturing arrangement
CN204768324U (en) * 2015-06-12 2015-11-18 安徽美欣制药有限公司 Intelligence heat preservation agitator
CN105964176A (en) * 2016-06-28 2016-09-28 大唐南京发电厂 System and method for automatically preparing flocculant solution

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020262175A1 (en) * 2019-06-26 2020-12-30 日機装株式会社 Blood purification system and raw liquid preparation determination device
US11969530B2 (en) 2019-06-26 2024-04-30 Nikkiso Company Limited Blood purification system and solution-preparation-determining apparatus

Also Published As

Publication number Publication date
CN108619925B (en) 2021-11-09
JP6831279B2 (en) 2021-02-17
CN108619925A (en) 2018-10-09

Similar Documents

Publication Publication Date Title
EP3454922B1 (en) Infusion pump system with common line auto flush
JP6391836B2 (en) Pre-diagnosis of infusion device operational mode feasibility
US9333291B2 (en) Infusion pump battery capacity management and battery charge alert system and method
CN104922747B (en) Liquid-feeding pump
CA2745091C (en) Drug component admixture library for a drug infusion delivery system
JPS60220072A (en) Apparatus for intermittent pulsating administration of liquid agent
JP2008104737A (en) Peritoneal dialyzer
JP4475466B2 (en) Dissolving apparatus and dissolving method therefor
JP2018153557A (en) Melting device
JP6435127B2 (en) Melting equipment
JP2015002752A (en) Drug container
JP2009011667A (en) Automated peritoneal dialysis apparatus
JP2021000354A (en) Dissolving apparatus
JP4812116B2 (en) Dissolution system and dissolution method using the same
JP4975340B2 (en) Dissolving apparatus and dissolving method therefor
JP6644857B2 (en) Melting equipment
JP2008220774A (en) Dissolving apparatus and residual quantity measuring method in its reservoir
JP6424031B2 (en) Melting equipment
JP2012223248A (en) Peritoneal dialyzer control system
JP2016195829A (en) Portable injection device and control method for portable injection device
TW202110498A (en) Blood purification system and raw liquid preparation determination device
CN116942954A (en) Intelligent serosal cavity perfusion transfusion device, system and application method thereof
KR20220128675A (en) Compensation for Missing Readings in Glucose Monitor in Automated Insulin Delivery System
JP2018175285A (en) Dialysis powder dissolving apparatus and dialysis powder dissolving method

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20191121

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20200908

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20201019

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20201217

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20210122

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20210128

R150 Certificate of patent or registration of utility model

Ref document number: 6831279

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250