JP2016525099A5 - 免疫グロブリンＦｃ断片のＦｃＲｎに対する結合親和力が維持される免疫グロブリンＦｃ結合体 - Google Patents
免疫グロブリンＦｃ断片のＦｃＲｎに対する結合親和力が維持される免疫グロブリンＦｃ結合体 Download PDFInfo
- Publication number
- JP2016525099A5 JP2016525099A5 JP2016525294A JP2016525294A JP2016525099A5 JP 2016525099 A5 JP2016525099 A5 JP 2016525099A5 JP 2016525294 A JP2016525294 A JP 2016525294A JP 2016525294 A JP2016525294 A JP 2016525294A JP 2016525099 A5 JP2016525099 A5 JP 2016525099A5
- Authority
- JP
- Japan
- Prior art keywords
- immunoglobulin
- fcrn
- conjugates
- fragments
- retain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102100014838 FCGRT Human genes 0.000 title 1
- 101710003435 FCGRT Proteins 0.000 title 1
- 102000018071 Immunoglobulin Fc Fragments Human genes 0.000 title 1
- 108010091135 Immunoglobulin Fc Fragments Proteins 0.000 title 1
- 102000018358 Immunoglobulins Human genes 0.000 title 1
- 108060003951 Immunoglobulins Proteins 0.000 title 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20130082509 | 2013-07-12 | ||
| KR10-2013-0082509 | 2013-07-12 | ||
| PCT/KR2014/006328 WO2015005747A1 (ko) | 2013-07-12 | 2014-07-14 | FcRn 결합력이 유지되는 면역글로불린 Fc 결합체 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020078005A Division JP6880278B2 (ja) | 2013-07-12 | 2020-04-27 | 免疫グロブリンＦｃ断片のＦｃＲｎに対する結合親和力が維持される免疫グロブリンＦｃ結合体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016525099A JP2016525099A (ja) | 2016-08-22 |
| JP2016525099A5 true JP2016525099A5 (ja) | 2017-08-31 |
Family
ID=52280325
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016525294A Pending JP2016525099A (ja) | 2013-07-12 | 2014-07-14 | ＦｃＲｎ結合力が維持される免疫グロブリンＦｃ結合体 |
| JP2020078005A Active JP6880278B2 (ja) | 2013-07-12 | 2020-04-27 | 免疫グロブリンＦｃ断片のＦｃＲｎに対する結合親和力が維持される免疫グロブリンＦｃ結合体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020078005A Active JP6880278B2 (ja) | 2013-07-12 | 2020-04-27 | 免疫グロブリンＦｃ断片のＦｃＲｎに対する結合親和力が維持される免疫グロブリンＦｃ結合体 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US20160152684A1 (ja) |
| EP (1) | EP3020732B1 (ja) |
| JP (2) | JP2016525099A (ja) |
| KR (2) | KR101872559B1 (ja) |
| CN (2) | CN116082528A (ja) |
| AR (1) | AR096890A1 (ja) |
| AU (1) | AU2014287879B2 (ja) |
| CA (1) | CA2917838C (ja) |
| DK (1) | DK3020732T3 (ja) |
| EA (1) | EA034297B1 (ja) |
| ES (1) | ES2799326T3 (ja) |
| HK (1) | HK1221957A1 (ja) |
| HU (1) | HU231424B1 (ja) |
| IL (1) | IL243567B (ja) |
| MX (1) | MX2016000344A (ja) |
| MY (1) | MY180374A (ja) |
| NO (1) | NO20160182A1 (ja) |
| PH (1) | PH12016500111A1 (ja) |
| PT (1) | PT3020732T (ja) |
| TW (1) | TWI693236B (ja) |
| UA (1) | UA119644C2 (ja) |
| WO (1) | WO2015005747A1 (ja) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130049671A (ko) | 2011-11-04 | 2013-05-14 | 한미사이언스 주식회사 | 생리활성 폴리펩타이드 결합체 제조 방법 |
| AR090281A1 (es) | 2012-03-08 | 2014-10-29 | Hanmi Science Co Ltd | Proceso mejorado para la preparacion de un complejo polipeptidico fisiologicamente activo |
| SG10202107752PA (en) * | 2014-03-31 | 2021-09-29 | Hanmi Pharmaceutical Co Ltd | Method for improving solubility of protein and peptide by using immunoglobulin fc fragment linkage |
| AR107483A1 (es) | 2016-01-29 | 2018-05-02 | Hanmi Pharm Ind Co Ltd | Conjugado de enzimas terapéuticas |
| US20190352335A1 (en) * | 2016-12-19 | 2019-11-21 | Hanmi Pharm. Co., Ltd. | Brain targeting long-acting protein conjugate |
| WO2021010531A1 (ko) * | 2019-07-18 | 2021-01-21 | 한미약품 주식회사 | 단백질 결합체의 신규 제조 방법 |
| KR102382593B1 (ko) * | 2020-01-29 | 2022-04-05 | 고려대학교 산학협력단 | pH-감응성 Fc 변이체 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6030613A (en) * | 1995-01-17 | 2000-02-29 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| WO1997034631A1 (en) | 1996-03-18 | 1997-09-25 | Board Of Regents, The University Of Texas System | Immunoglobin-like domains with increased half lives |
| UA91325C2 (ru) * | 2002-12-26 | 2010-07-26 | Маунтин Вью Фармасьютикалз, Инк. | Полимерные конъюгаты цитокинов, хемокинов, факторов роста, полипептидных гормонов и их антагонистов с сохраненной активностью рецепторного связывания |
| US20050176108A1 (en) * | 2003-03-13 | 2005-08-11 | Young-Min Kim | Physiologically active polypeptide conjugate having prolonged in vivo half-life |
| BRPI0406605B8 (pt) * | 2003-11-13 | 2021-05-25 | Hanmi Holdings Co Ltd | conjugado de proteína, método para a preparação do mesmo e composição farmacêutica para intensificar a duração e estabilidade in vivo de um polipeptídeo fisiologicamente ativo |
| KR100609434B1 (ko) | 2004-12-30 | 2006-08-03 | 한국항공우주연구원 | 트랜스버살 필터 |
| KR100754667B1 (ko) * | 2005-04-08 | 2007-09-03 | 한미약품 주식회사 | 비펩타이드성 중합체로 개질된 면역글로불린 Ｆｃ 단편 및이를 포함하는 약제학적 조성물 |
| US7625564B2 (en) * | 2006-01-27 | 2009-12-01 | Novagen Holding Corporation | Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo |
| JP2008169195A (ja) * | 2007-01-05 | 2008-07-24 | Hanmi Pharmaceutical Co Ltd | キャリア物質を用いたインスリン分泌ペプチド薬物結合体 |
| KR20080098216A (ko) * | 2007-05-04 | 2008-11-07 | 한미약품 주식회사 | 캐리어 물질을 이용한 나트륨 배설 펩타이드 약물 결합체 |
| WO2008147143A2 (en) * | 2007-05-30 | 2008-12-04 | Postech Academy-Industry Foundation | Immunoglobulin fusion proteins |
| JP2009019027A (ja) | 2007-07-16 | 2009-01-29 | Hanmi Pharmaceutical Co Ltd | アミノ末端のアミノ酸が変異したインスリン分泌ペプチド誘導体 |
| AR072596A1 (es) * | 2008-07-23 | 2010-09-08 | Hanmi Pharmaceutical Co Ltd | Un complejo proteico que comprende una proteina dimerica y un polimero no peptidico |
| CN102844332B (zh) * | 2010-03-11 | 2015-08-19 | 瑞纳神经科学公司 | 呈pH依赖性抗原结合的抗体 |
| AR081066A1 (es) * | 2010-04-02 | 2012-06-06 | Hanmi Holdings Co Ltd | Conjugado de insulina donde se usa un fragmento de inmunoglobulina |
| KR101333958B1 (ko) * | 2010-10-20 | 2013-11-27 | 주식회사 한독 | 인간 인터루킨-1 수용체 길항제-하이브리드 Ｆｃ 융합단백질 |
| UA113626C2 (xx) * | 2011-06-02 | 2017-02-27 | Композиція для лікування діабету, що містить кон'югат інсуліну тривалої дії та кон'югат інсулінотропного пептиду тривалої дії | |
| ES2968043T3 (es) | 2011-06-10 | 2024-05-06 | Hanmi Science Co Ltd | Nuevos derivados de oxintomodulina y composición farmacéutica para el tratamiento de la obesidad que comprende la misma |
| KR101577734B1 (ko) * | 2011-06-17 | 2015-12-29 | 한미사이언스 주식회사 | 옥신토모듈린과 면역글로불린 단편을 포함하는 결합체 및 그의 용도 |
| BR112014005091A2 (pt) * | 2011-09-05 | 2017-06-13 | Beijing Hanmi Pharmaceutical Co Ltd | composição farmacêutica para o tratamento do câncer compreendendo conjugado de interferon alfa |
| KR20130049671A (ko) * | 2011-11-04 | 2013-05-14 | 한미사이언스 주식회사 | 생리활성 폴리펩타이드 결합체 제조 방법 |
| KR102041412B1 (ko) * | 2011-12-30 | 2019-11-11 | 한미사이언스 주식회사 | 면역글로불린 Ｆｃ 단편 유도체 |
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2014
- 2014-07-11 AR ARP140102575A patent/AR096890A1/es unknown
- 2014-07-14 EP EP14822721.8A patent/EP3020732B1/en active Active
- 2014-07-14 UA UAA201600304A patent/UA119644C2/uk unknown
- 2014-07-14 MX MX2016000344A patent/MX2016000344A/es active IP Right Grant
- 2014-07-14 WO PCT/KR2014/006328 patent/WO2015005747A1/ko active Application Filing
- 2014-07-14 CN CN202310310247.2A patent/CN116082528A/zh active Pending
- 2014-07-14 AU AU2014287879A patent/AU2014287879B2/en active Active
- 2014-07-14 EA EA201690114A patent/EA034297B1/ru unknown
- 2014-07-14 TW TW103124093A patent/TWI693236B/zh active
- 2014-07-14 JP JP2016525294A patent/JP2016525099A/ja active Pending
- 2014-07-14 US US14/904,543 patent/US20160152684A1/en not_active Abandoned
- 2014-07-14 ES ES14822721T patent/ES2799326T3/es active Active
- 2014-07-14 CN CN201480049342.0A patent/CN105593243A/zh active Pending
- 2014-07-14 PT PT148227218T patent/PT3020732T/pt unknown
- 2014-07-14 KR KR1020140088530A patent/KR101872559B1/ko active Application Filing
- 2014-07-14 DK DK14822721.8T patent/DK3020732T3/da active
- 2014-07-14 HU HUP1600206A patent/HU231424B1/hu unknown
- 2014-07-14 MY MYPI2016000028A patent/MY180374A/en unknown
- 2014-07-14 CA CA2917838A patent/CA2917838C/en active Active
-
2016
- 2016-01-11 IL IL243567A patent/IL243567B/en active IP Right Grant
- 2016-01-12 PH PH12016500111A patent/PH12016500111A1/en unknown
- 2016-02-03 NO NO20160182A patent/NO20160182A1/en unknown
- 2016-08-23 HK HK16110033.0A patent/HK1221957A1/zh unknown
-
2018
- 2018-06-19 KR KR1020180070435A patent/KR102076718B1/ko active IP Right Grant
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2020
- 2020-04-27 JP JP2020078005A patent/JP6880278B2/ja active Active
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2022
- 2022-08-03 US US17/880,358 patent/US20220380437A1/en active Pending
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