JP2016077646A - Organ separation operation tool - Google Patents
Organ separation operation tool Download PDFInfo
- Publication number
- JP2016077646A JP2016077646A JP2014213250A JP2014213250A JP2016077646A JP 2016077646 A JP2016077646 A JP 2016077646A JP 2014213250 A JP2014213250 A JP 2014213250A JP 2014213250 A JP2014213250 A JP 2014213250A JP 2016077646 A JP2016077646 A JP 2016077646A
- Authority
- JP
- Japan
- Prior art keywords
- conductor
- brush
- insulator
- resection tool
- organ resection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B2017/320004—Surgical cutting instruments abrasive
- A61B2017/320012—Brushes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00107—Coatings on the energy applicator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00184—Moving parts
- A61B2018/0019—Moving parts vibrating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00601—Cutting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00994—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body combining two or more different kinds of non-mechanical energy or combining one or more non-mechanical energies with ultrasound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
- A61B2018/1861—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument inserted into a body lumen or cavity, e.g. a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2218/00—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2218/001—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body having means for irrigation and/or aspiration of substances to and/or from the surgical site
- A61B2218/007—Aspiration
Abstract
Description
本発明は、刷毛状構造体を有しかつマイクロ波照機能を有する臓器切離操作具に関する。 The present invention relates to an organ resection tool having a brush-like structure and having a microwave irradiation function.
（実質臓器）
実質臓器（脳、肝臓、脾臓、腎臓、膵臓等）は、小血管に富み、どこを切っても出血する構造を有する。特に、毛細血管が極めて豊富で軟らかい実質臓器として、肝、膵、脾、腎臓等が挙げられる。一方で、実質臓器は、豆腐よりは固いが管腔臓器のようにしっかりした組織ではなく、振動子をあてることによってソニケイトされ、細胞組織がバラバラとなって切窟することができる。
これらの臓器切除に関し、臓器組織を薄く切除する場合には、主に、超音波凝固切断器や高周波凝固切断器が使用されている。しかし、１ｃｍ以上深い臓器部位を切除する場合には、血管が太く、超音波凝固切断器や高周波凝固切断器が使用できない。よって、より深い臓器部位の切除の場合には、高周波や超音波振動（キャビテーション）を利用した超音波吸引器（CUSA等）が用いられている。しかし、これら器具でも微細な出血が十分抑えられない。さらに、肝組織が硬い肝硬変肝臓では、特に肝癌が発生しやすいにもかかわらず、超音波吸引装置は切離能力が不十分である。最も出血しやすく症例の多い肝硬変肝切除に対処しきれていないのが手術器具の現状である。
また、市販の医療機器は、振動子で臓器組織を壊した後、水を出して洗い流し、それを吸入する。この操作を繰り返し、微細な血管部分の実質臓器を切離する。振動子は、超音波を発生させるための超音波振動子と、前記超音波振動子において発生した超音波を、対象物に伝達する伝達部材を含む（特許文献１）。
(Parenchymal organ)
Real organs (brain, liver, spleen, kidney, pancreas, etc.) are rich in small blood vessels and have a structure that bleeds no matter where they are cut. In particular, liver, pancreas, spleen, kidney and the like can be mentioned as soft parenchymal organs that are extremely rich in capillaries. On the other hand, the real organ is harder than tofu, but not a solid tissue like a luminal organ, and is sonicated by applying a vibrator, so that the cellular tissue can be separated and cut.
With respect to these organ resections, ultrasonic coagulation / cutting devices and high-frequency coagulation / cutting devices are mainly used when organ tissues are cut thinly. However, when an organ site deeper than 1 cm is excised, the blood vessel is thick and an ultrasonic coagulation / cutting device or a high-frequency coagulation / cutting device cannot be used. Therefore, in the case of excision of a deeper organ site, an ultrasonic aspirator (CUSA or the like) using high frequency or ultrasonic vibration (cavitation) is used. However, even these devices cannot sufficiently suppress fine bleeding. Furthermore, in the cirrhosis liver where the liver tissue is hard, the ultrasonic aspirator has insufficient separation ability even though liver cancer is particularly likely to occur. The current state of surgical instruments has not been able to cope with cirrhotic hepatectomy, which is most likely to bleed and has many cases.
In addition, commercially available medical devices break organ tissue with a vibrator, and then wash out the water and inhale it. This operation is repeated, and the parenchymal organ of the fine blood vessel part is separated. The vibrator includes an ultrasonic vibrator for generating an ultrasonic wave and a transmission member that transmits the ultrasonic wave generated in the ultrasonic vibrator to an object (Patent Document 1).
（先行特許文献）
国際公開2013/172361号公報（特許文献２）では、「マイクロ波照射可能な刷毛状構造体及び／又はマイクロ波の受け手となることが可能な刷毛状構造体を含む臓器切離操作具」を開示している。該臓器切離操作具は、複数の刷毛状構造体間でマイクロ波を印加して受け取る。当然に、刷毛状構造体は、マイクロ波照射可能な材質に限定されている。
(Prior Patent Literature)
In International Publication 2013/172361 (Patent Document 2), “a brush-like structure capable of microwave irradiation and / or an organ resection tool including a brush-like structure capable of receiving a microwave” Disclosure. The organ resection tool applies and receives microwaves between a plurality of brush-like structures. Naturally, the brush-like structure is limited to materials that can be irradiated with microwaves.
特開2001-61847号公報（特許文献３）では、「超音波振動を発生させる超音波振動子と、この超音波振動子からの超音波振動を先端側に伝達するプローブと、生体組織と前記プローブの先端部との間に超音波振動を伝達する超音波振動伝達媒体を注入する媒体注入手段と、前記プローブからの超音波振動を前記超音波振動伝達媒体を介して生体組織に伝達し、この超音波振動伝達媒体を介して伝達される超音波振動によって生体組織を除去する生体組織の除去手段とを具備したことを特徴とする生体組織の処置具」を開示している。
しかし、本発明の臓器切離操作具の刷毛状構造体を開示又は示唆をしていない。
In Japanese Patent Laid-Open No. 2001-61847 (Patent Document 3), “an ultrasonic transducer that generates ultrasonic vibrations, a probe that transmits ultrasonic vibrations from the ultrasonic transducers to the distal end side, Medium injection means for injecting an ultrasonic vibration transmission medium that transmits ultrasonic vibration between the tip of the probe, and transmitting ultrasonic vibration from the probe to the living tissue via the ultrasonic vibration transmission medium; A biological tissue treatment tool comprising a biological tissue removing means for removing biological tissue by ultrasonic vibration transmitted via the ultrasonic vibration transmission medium is disclosed.
However, the brush-like structure of the organ resection tool of the present invention is not disclosed or suggested.
実開昭62-001605号公報（特許文献４）では、「後端がマイクロ波発生装置に接続する高周波同軸ケーブル先端の中心導体及び外部導体にそれぞれ針状電極を接続し、前記両針状電極をこれらの電極の先端部を露出されるように剛性の切刃形状の誘電体で包囲して成るマイクロ波メス」を開示している。
しかし、本発明の臓器切離操作具の刷毛状構造体を開示又は示唆をしていない。
In Japanese Utility Model Publication No. 62-001605 (Patent Document 4), “a needle electrode is connected to the center conductor and the outer conductor at the tip of the high-frequency coaxial cable whose rear end is connected to the microwave generator, The microwave knife is disclosed that is surrounded by a dielectric having a rigid cutting edge shape so that the tip portions of these electrodes are exposed.
However, the brush-like structure of the organ resection tool of the present invention is not disclosed or suggested.
特表2010-527704号公報（特許文献５）では、「組織付着及び強化のための装置であって、前記装置は、第１の組織接触面の近くに配置されたエネルギーアプリケータと、第２の組織接触面に配置されたバイオポリマーアプリケータと、を備え、前記エネルギーアプリケータは、対象組織内に熱を発生させるため一定量のエネルギーを付与するよう構成され、これにより前記対象組織から細胞内・細胞外水分が蒸発し組織は乾燥し、且つ前記対象組織の中でコラーゲンとエラスチンとのうちの少なくとも一方は変性し前記対象組織の部分がともに付着し、前記バイオポリマーアプリケータは、前記対象組織に付与された前記エネルギーによって発生する前記熱を受けるため、前記対象組織に近い場所でバイオポリマー材を収容するよう構成され、これにより前記バイオポリマー材は固体状態から融解状態に相を変化させ、且つ前記乾燥組織には前記バイオポリマーが充満し前記対象組織が互いに付着した前記部分は強化され、前記バイオポリマーが冷えて前記固体状態に戻ることにより気密封止されること、を特徴とする装置。」を開示している。
しかし、本発明の臓器切離操作具の刷毛状構造体を開示又は示唆をしていない。
In Japanese translation of PCT publication No. 2010-527704 (patent document 5), “a device for tissue attachment and strengthening, the device includes an energy applicator disposed near the first tissue contact surface, A biopolymer applicator disposed on a tissue contacting surface of the device, wherein the energy applicator is configured to impart a certain amount of energy to generate heat in the target tissue, thereby causing cells from the target tissue to Internal and extracellular moisture evaporates, the tissue dries, and at least one of collagen and elastin is denatured in the target tissue and the target tissue part adheres together, the biopolymer applicator is In order to receive the heat generated by the energy applied to the target tissue, the biopolymer material is accommodated in a place close to the target tissue, As a result, the biopolymer material changes its phase from a solid state to a molten state, and the dry tissue is filled with the biopolymer and the target tissue adheres to each other, and the biopolymer cools and the biopolymer cools. An apparatus characterized in that it is hermetically sealed by returning to the solid state. "
However, the brush-like structure of the organ resection tool of the present invention is not disclosed or suggested.
さらに、振動子と高周波電流を組み合わせた手術器具も報告されている。
特開2008-055151号公報（特許文献６）では、「先端側に生体組織を処置する処置部が設けられ、指示により高周波電流が供給されるプローブと、前記プローブに固着され、該プローブを超音波振動させる超音波振動子とを備えるハンドピースと、 前記プローブに高周波電流を供給する高周波駆動回路と、前記超音波振動子を駆動する超音波振動子駆動回路と、を具備し、前記超音波振動子駆動回路は、前記高周波駆動回路にて検出される高周波出力時のインピーダンス値の大きさに合わせて、前記処置部における超音波振動の振幅を制御することを特徴とする手術用処置装置」を開示している。
しかし、この装置は、メス先電極により生じる生体組織の焦げ付きを防止するためのみに提供されている。
Furthermore, a surgical instrument combining a vibrator and a high-frequency current has been reported.
In JP 2008-055151 A (Patent Document 6), “a treatment section for treating a living tissue is provided on the distal end side, a probe to which a high-frequency current is supplied according to an instruction, and a probe that is fixed to the probe. A handpiece including an ultrasonic transducer for oscillating the ultrasonic wave, a high-frequency driving circuit for supplying a high-frequency current to the probe, and an ultrasonic transducer driving circuit for driving the ultrasonic transducer, The vibrator driving circuit controls the amplitude of the ultrasonic vibration in the treatment section in accordance with the magnitude of the impedance value at the time of high-frequency output detected by the high-frequency driving circuit. Is disclosed.
However, this device is provided only for preventing scorching of the living tissue caused by the scalpel tip electrode.
従来の臓器切離操作具では、以下の課題があることを新たに見出した。
（課題１）
○刷毛状構造体間でマイクロ波を照射・受け手とする場合には、該刷毛状構造体は伝導体以外の材質を用いることが困難である。
○刷毛状構造体の臓器切除に最適な刷毛状構造体の配置が特定されていない。
（課題２）
○臓器への切除・擦過において、血液やタンパク質の刷毛先端の中心部への組織固着が著しい。
○マイクロ波による加熱により刷毛部に固着した組織物を取り除くのが困難である。
○刷毛状構造体の臓器切除に最適なサイズ、特性が特定されていない。
It has been newly found that the conventional organ resection tool has the following problems.
(Problem 1)
In the case where microwaves are irradiated / received between brush-like structures, it is difficult to use materials other than conductors for the brush-like structures.
○ The optimal arrangement of brush-like structures for organ resection of brush-like structures has not been identified.
(Problem 2)
○ Tissue adherence to the central part of the brush tip of blood or protein is remarkable during excision and abrasion to organs.
○ It is difficult to remove tissue adhered to the brush portion by heating with microwaves.
○ The optimal size and characteristics for organ resection of brush-like structures have not been specified.
（課題３）
○狭視下（鏡視下等）では、操作範囲が限定されるため、該操作具を上下左右に動かすことなく切除を行うことができる必要がある。
○臓器切除により刷毛先端に溜まった固着物が、マイクロ波照射による凝固能の低下をもたらすので、該固着物を除去する必要がある。
(Problem 3)
○ Under narrow viewing (such as under mirror viewing), the operating range is limited, and therefore it is necessary to be able to perform excision without moving the operating tool up and down and left and right.
○ The solid matter collected at the tip of the brush due to organ excision brings about a decrease in coagulation ability due to microwave irradiation. Therefore, it is necessary to remove the solid matter.
本発明者らは、上記課題１を解決するために鋭意研究を重ねた結果、絶縁体に直接又は間接的に接続している刷毛状構造体を有する臓器切離操作具、さらには、該刷毛状構造体の配置を最適化した臓器切離操作具（以後、「非伝導体接続刷毛状構造体を有する臓器切離具」と称する場合がある）が、上記課題１を解決できることを見出した。
また、本発明者らは、上記課題２を解決するために鋭意研究を重ねた結果、刷毛状構造体の配列設定、先端の被膜処理、又は先端のコーティング処理若しくはダイヤモンド研磨処理した臓器切離操作具（以後、「最適化刷毛状構造体を有する臓器切離具」と称する場合がある）が、上記課題２を解決できることを見出した。
さらに、本発明者らは、上記課題３を解決するために鋭意研究を重ねた結果、上記課題１又は上記課題２を解決した臓器切離操作具に、刷毛状構造体の先端が左右交互又は一方向に回転動作可能であるように導入する、並びに、振動機能手段及び／又は吸引機能手段を導入することを特徴とする臓器切離操作具（以後、「刷毛状構造体及び補助手段を有する臓器切離具」と称する場合がある）が、上記課題３を解決できることを見出した。
As a result of intensive studies in order to solve the above-mentioned problem 1, the present inventors have made an organ resection tool having a brush-like structure directly or indirectly connected to an insulator, and further, the brush It has been found that an organ resection tool (hereinafter, sometimes referred to as an “organ resection tool having a non-conductor-connected brush-like structure”) that optimizes the arrangement of the structure is able to solve the problem 1. .
In addition, as a result of intensive studies to solve the above-mentioned problem 2, the present inventors have made arrangements of brush-like structures, tip coating treatment, or tip cutting treatment or organ polishing operation subjected to diamond polishing treatment. It has been found that a tool (hereinafter, sometimes referred to as “an organ resection tool having an optimized brush-like structure”) can solve the above problem 2.
Furthermore, as a result of intensive studies to solve the above-mentioned problem 3, the present inventors have found that the tip of the brush-like structure is alternately left or right in the organ resection tool that has solved the above-mentioned problem 1 or 2 An organ resection tool (hereinafter referred to as “having a brush-like structure and auxiliary means”, characterized in that it is introduced so that it can rotate in one direction, and vibration function means and / or suction function means are introduced. It has been found that the above-mentioned problem 3 can be solved.
すなわち本発明は、以下からなる。
１．以下の構成を含む臓器切離操作具であって、
（１）中心導体又はマイクロ波印加用導体
（２）外部導体又はマイクロ波受手用導体
（３）該中心導体、該マイクロ波印加用導体、該外部導体又は該マイクロ波受手用導体の一部又は全部を覆う絶縁体
（４）該絶縁体に直接又は間接的に接続している刷毛状構造体、又は、該中心導体、該マイクロ波印加用導体、該外部導体又は該マイクロ波受手用導体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
２．以下の構成を含む前項１に記載の臓器切離操作具であって、
（１）前記中心導体は中空円柱形状の中心導体であり、
（２）該中心導体の内部の一部又は全部を埋める内部絶縁体
（３）該中心導体の外部の一部又は全部を覆う中部絶縁体、
（４）該中部絶縁体の一部又は全部を覆う外部導体、及び
（５）該内部絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
３．以下の構成を含む前項１に記載の臓器切離操作具であって、
（１）前記中心導体は中空円柱形状の中心導体であり、
（２）該中心導体の内部の一部又は全部を埋める内部絶縁体
（３）該中心導体の外部の一部又は全部を覆う中部絶縁体、
（４）該中部絶縁体の一部又は全部を覆う外部導体、及び
（５）該中部絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
４．以下の構成を含む前項１に記載の臓器切離操作具であって、
（１）前記中心導体は中空円柱形状の中心導体であり、
（２）該中心導体の内部の一部又は全部を埋める内部絶縁体
（３）該中心導体の外部の一部又は全部を覆う中部絶縁体、
（４）該中部絶縁体の一部又は全部を覆う外部導体、及び
（５）該内部絶縁体及び該中部絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
５．以下の構成を含む前項１に記載の臓器切離操作具であって、
（１）前記中心導体は中空円柱形状の中心導体であり、
（２）該中心導体の内部の一部又は全部を埋める内部絶縁体
（３）該中心導体の外部の一部又は全部を覆う中部絶縁体、
（４）該中部絶縁体の一部又は全部を覆う外部導体、
（５）該外部導体の一部又は全部を覆う外部絶縁体、及び
（６）該内部絶縁体、該中部絶縁体及び該外部絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
６．以下の構成を含む前項１に記載の臓器切離操作具であって、
（１）前記マイクロ波印加用導体、
（２）前記マイクロ波受手用導体、
（３）該マイクロ波印加用導体と該マイクロ波受手用導体が略平行に位置しかつ該マイクロ波受手用導体は、該マイクロ波印加用導体に対して該切離具の先端断面の外側に位置し、両導体の４つの端で形成される領域の印加受手導体間絶縁体、及び
（４）該印加受手導体間絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
７．以下の構成を含む前項６に記載の臓器切離操作具であって、
（１）前記印加受手導体間絶縁体を２以上有し、
（２）前記２つのマイクロ波印加用導体間の４つの端で形成される領域の両導体間絶縁体、及び
（３）該両導体間絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
８．以下の構成を含む前項６に記載の臓器切離操作具であって、
（１）前記印加受手導体間絶縁体を２以上有し、
（２）前記２つのマイクロ波印加用導体間の４つの端で形成される領域の両導体間絶縁体、及び
（３）該印加受手導体間絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
９．以下の構成を含む前項６〜８のいずれか１に記載の臓器切離操作具であって、
（１）前記印加受手導体間絶縁体を２以上有し、
（２）前記両導体間絶縁体、及び
（３）該印加受手導体間絶縁体及び両導体間絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
１０．以下の構成を含む前項６に記載の臓器切離操作具であって、
（１）前記印加受手導体間絶縁体を２以上有し、
（２）前記２つのマイクロ波印加用導体間の４つの端で形成される領域の両導体間絶縁体、
（３）前記マイクロ波受手用導体が前記マイクロ波印加用導体とは反対側に形成される領域である外側絶縁体、及び
（４）該印加受手導体間絶縁体、両導体間絶縁体及び外側絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
１１．前項１〜１０のいずれか１に記載の臓器切離操作具であって、
前記１又は複数の刷毛状構造体が、その先端近傍まで絶縁材料で被覆されていることを特徴とする臓器切離操作具。
１２．前項１又は１１に記載の臓器切離操作具であって、
前記外部導体又はマイクロ波受手用導体に直接又は間接的に接続した複数の刷毛状構造体が、一列の直線状に配置されていることを特徴とする臓器切離操作具。
１３．前項１、１１〜１２のいずれか１に記載の臓器切離操作具であって、
前記中心導体又はマイクロ波印加用導体に直接又は間接的に接続した複数の刷毛状構造体が、一列の直線状に配置されていることを特徴とする臓器切離操作具。
１４．前項１、１１〜１３のいずれか１に記載の臓器切離操作具であって、
前記外部導体又はマイクロ波受手用導体に直接又は間接的に接続した複数の刷毛状構造体並びに前記中心導体又はマイクロ波印加用導体に直接又は間接的に接続した複数の刷毛状構造体が、直線状の一列に配置されていることを特徴とする臓器切離操作具。
１５．前項１、１１〜１３のいずれか１に記載の臓器切離操作具であって、
前記外部導体又はマイクロ波受手用導体に直接又は間接的に接続した複数の刷毛状構造体が直線状の一列に配置されており、並びに、前記中心導体又はマイクロ波印加用導体に直接又は間接的に接続した複数の刷毛状構造体が直線状の一列に配置されており、さらにそれらの２列が略平行であることを特徴とする臓器切離操作具。
１６．前項１〜１５のいずれか１に記載の臓器切離操作具であって、
前記刷毛状構造体の先端がフッ素系コーティング処理、シリコン系コーディング処理、又はダイヤモンド研磨処理されていることを特徴とする臓器切離操作具。
１７．前項１〜１６のいずれか１に記載の臓器切離操作具であって、
前記刷毛状構造体の先端が右左交互又は一方向に回転動作することを特徴とする臓器切離操作具。
１８．前項１〜１７のいずれか１に記載の臓器切離操作具であって、
さらに、振動機能手段を有し、
前記刷毛状構造体の先端が振動させることを特徴とする臓器切離操作具。
１９．前項１〜１８のいずれか１に記載の臓器切離操作具であって
さらに、吸引機能手段を有することを特徴とする臓器切離操作具。」
That is, this invention consists of the following.
1. An organ resection tool including the following configuration,
(1) Center conductor or microwave application conductor (2) Outer conductor or microwave receiver conductor (3) One of the center conductor, microwave application conductor, outer conductor or microwave receiver conductor Insulator covering part or all (4) Brush-like structure directly or indirectly connected to the insulator, or the central conductor, the microwave applying conductor, the external conductor or the microwave receiver A brush-like structure connected directly or indirectly to the conductor for
Organ resection tool.
2. The organ resection tool according to item 1, comprising the following configuration:
(1) The central conductor is a hollow cylindrical central conductor,
(2) An internal insulator that fills part or all of the inside of the central conductor (3) A middle insulator that covers part or all of the outside of the central conductor,
(4) including an outer conductor covering a part or all of the middle insulator, and (5) a brush-like structure directly or indirectly connected to the inner insulator.
Organ resection tool.
3. The organ resection tool according to item 1, comprising the following configuration:
(1) The central conductor is a hollow cylindrical central conductor,
(2) An internal insulator that fills part or all of the inside of the central conductor (3) A middle insulator that covers part or all of the outside of the central conductor,
(4) an outer conductor covering a part or all of the middle insulator, and (5) a brush-like structure directly or indirectly connected to the middle insulator.
Organ resection tool.
4). The organ resection tool according to item 1, comprising the following configuration:
(1) The central conductor is a hollow cylindrical central conductor,
(2) An internal insulator that fills part or all of the inside of the central conductor (3) A middle insulator that covers part or all of the outside of the central conductor,
(4) an outer conductor covering part or all of the middle insulator, and (5) a brush-like structure directly or indirectly connected to the inner insulator and the middle insulator.
Organ resection tool.
5. The organ resection tool according to item 1, comprising the following configuration:
(1) The central conductor is a hollow cylindrical central conductor,
(2) An internal insulator that fills part or all of the inside of the central conductor (3) A middle insulator that covers part or all of the outside of the central conductor,
(4) an outer conductor covering part or all of the middle insulator;
(5) an external insulator covering part or all of the outer conductor, and (6) a brush-like structure directly or indirectly connected to the inner insulator, the middle insulator, and the outer insulator, including,
Organ resection tool.
6). The organ resection tool according to item 1, comprising the following configuration:
(1) The microwave application conductor,
(2) the microwave receiver conductor;
(3) The microwave application conductor and the microwave receiver conductor are positioned substantially in parallel, and the microwave receiver conductor has a cross-section of the tip of the cutting tool with respect to the microwave application conductor. An insulator between applied receiver conductors in a region located on the outside and formed by four ends of both conductors; and (4) a brush-like structure connected directly or indirectly to the insulator between applied receiver conductors Body, including,
Organ resection tool.
7). The organ resection tool according to the preceding item 6 including the following configuration,
(1) having two or more insulators between the application receiver conductors,
(2) a two-conductor insulator in a region formed by four ends between the two microwave application conductors; and (3) a brush-like shape directly or indirectly connected to the two-conductor insulator. Including,
Organ resection tool.
8). The organ resection tool according to the preceding item 6 including the following configuration,
(1) having two or more insulators between the application receiver conductors,
(2) An insulator between both conductors in a region formed by four ends between the two microwave application conductors, and (3) Directly or indirectly connected to the insulator between the application receiver conductors. A brush-like structure,
Organ resection tool.
9. The organ resection tool according to any one of items 6 to 8 including the following configuration,
(1) having two or more insulators between the application receiver conductors,
(2) the insulator between the two conductors, and (3) the brush-like structure directly or indirectly connected to the insulator between the applied receiver conductor and the insulator between the two conductors,
Organ resection tool.
10. The organ resection tool according to the preceding item 6 including the following configuration,
(1) having two or more insulators between the application receiver conductors,
(2) an inter-conductor insulator in a region formed by four ends between the two microwave application conductors;
(3) an outer insulator in which the microwave receiver conductor is a region formed on the side opposite to the microwave application conductor; and (4) an insulator between the application receiver conductor and an insulator between both conductors. And a brush-like structure connected directly or indirectly to the outer insulator,
Organ resection tool.
11 The organ resection tool according to any one of 1 to 10 above,
An organ resection tool, wherein the one or more brush-like structures are covered with an insulating material up to the vicinity of the tip thereof.
12 The organ resection tool according to the preceding item 1 or 11,
An organ resection tool comprising a plurality of brush-like structures directly or indirectly connected to the external conductor or the microwave receiver conductor arranged in a straight line.
13. The organ resection tool according to any one of the preceding items 1, 11 to 12,
An organ resection tool characterized in that a plurality of brush-like structures directly or indirectly connected to the central conductor or the microwave application conductor are arranged in a straight line.
14 The organ resection tool according to any one of the preceding items 1, 11 to 13,
A plurality of brush-like structures directly or indirectly connected to the outer conductor or the microwave receiver conductor and a plurality of brush-like structures directly or indirectly connected to the center conductor or the microwave application conductor, An organ resection tool characterized by being arranged in a straight line.
15. The organ resection tool according to any one of the preceding items 1, 11 to 13,
A plurality of brush-like structures directly or indirectly connected to the outer conductor or the microwave receiver conductor are arranged in a straight line, and directly or indirectly to the center conductor or the microwave application conductor. An organ resection tool characterized in that a plurality of connected brush-like structures are arranged in a straight line, and the two lines are substantially parallel.
16. The organ resection tool according to any one of items 1 to 15,
An organ resection tool, wherein a tip of the brush-like structure is subjected to a fluorine-based coating process, a silicon-based coding process, or a diamond polishing process.
17. The organ resection tool according to any one of 1 to 16 above,
An organ resection tool characterized in that the tip of the brush-like structure rotates right and left alternately or in one direction.
18. The organ resection tool according to any one of 1 to 17 above,
Furthermore, it has vibration function means,
An organ resection tool characterized in that the tip of the brush-like structure is vibrated.
19. 19. The organ resection tool according to any one of 1 to 18 above, further comprising suction function means. "
（非伝導体接続刷毛状構造体を有する臓器切離具）
マイクロ波が特定の領域に集中的に照射することが可能になり、切離対象の組織以外の箇所にマイクロ波が印加されることを極力防ぐことができる。これにより、マイクロ波照射による正常組織の損傷を防ぐことができる。
(Organectomy tool with non-conductor-connected brush-like structure)
It becomes possible to irradiate a specific area with a microwave in a concentrated manner, and it is possible to prevent the microwave from being applied to a portion other than the tissue to be separated as much as possible. Thereby, the damage of the normal tissue by microwave irradiation can be prevented.
（最適化刷毛状構造体を有する臓器切離具）
刷毛への固着除去効果が向上し、手術時間の短縮となる。また、刷毛形状の改良により操作性が向上し、太い血管を残しながらの擦過操作や切離操作が可能となる。加えて、様々な臓器（特に、実質臓器）の硬さに対応することができるので、臓器の切離が容易に達成することができる。特に、肝硬変等の固い組織を破砕することができる。
(Organectomy tool with optimized brush-like structure)
The effect of removing the sticking to the brush is improved, and the operation time is shortened. Further, the operability is improved by improving the brush shape, and a rubbing operation and a separation operation while leaving a thick blood vessel are possible. In addition, since it is possible to cope with the hardness of various organs (particularly, the parenchymal organs), organ resection can be easily achieved. In particular, hard tissues such as cirrhosis can be crushed.
（刷毛状構造体及び補助手段を有する臓器切離具）
刷毛を振動させる又は回転させることにより固着物が該刷毛から容易に除去することができる。また、手術者が、鏡視下において、刷毛の先端を左右上下の動作をすることなく擦過操作を行うことができる。
(An organ resection tool having a brush-like structure and auxiliary means)
The fixed matter can be easily removed from the brush by vibrating or rotating the brush. In addition, the surgeon can perform a rubbing operation without performing a left / right / up / down motion of the tip of the brush under a mirror.
（本発明の臓器切離操作具）
以下、本発明の「非伝導体接続刷毛状構造体を有する臓器切離具」、「最適化刷毛状構造体を有する臓器切離具」及び「刷毛状構造体及び補助手段を有する臓器切離具」は、少なくとも以下の構成を含む臓器切離操作具である。
（１）中心導体又はマイクロ波印加用導体。
（２）外部導体又はマイクロ波受手用導体。
（３）中心導体、マイクロ波印加用導体、外部導体又はマイクロ波受手用導体の一部又は全部を覆う絶縁体。
（４）絶縁体に直接又は間接的に接続している刷毛状構造体、又は、中心導体、マイクロ波印加用導体、外部導体又はマイクロ波受手用導体に直接又は間接的に接続している刷毛状構造体。
なお、刷毛状構造体が中心導体、マイクロ波印加用導体、外部導体又はマイクロ波受手用導体に直接又は間接的に接続している場合には、該刷毛状構造体はマイクロ波照射プローベ機能を有する。
中心導体と外部導体は、必要に応じて、絶縁体又は空隙を介して、互いに接触しないような構造になっている。同様に、マイクロ波印加用導体とマイクロ波受手用導体は、互いに接触しないような構造になっている。
なお、本発明の臓器切離操作具は、図面を参照して説明するが、本発明は図面に記載された臓器切離操作具に限定されるものではない。
(Organectomy tool of the present invention)
Hereinafter, the “organ separating device having a non-conductor-connected brush-like structure”, the “organ separating tool having an optimized brush-like structure” and the “organ separating device having a brush-like structure and auxiliary means” according to the present invention. “Tool” is an organ resection tool including at least the following components.
(1) Center conductor or microwave application conductor.
(2) External conductor or microwave receiver conductor.
(3) An insulator covering a part or all of the central conductor, the microwave applying conductor, the external conductor, or the microwave receiver conductor.
(4) A brush-like structure directly or indirectly connected to an insulator, or directly or indirectly connected to a central conductor, a microwave applying conductor, an external conductor or a microwave receiver conductor. Brush-like structure.
When the brush-like structure is directly or indirectly connected to the central conductor, the microwave application conductor, the external conductor, or the microwave receiver conductor, the brush-like structure functions as a microwave irradiation probe. Have
The center conductor and the outer conductor are structured such that they do not come into contact with each other via an insulator or a gap as necessary. Similarly, the microwave application conductor and the microwave receiver conductor are structured so as not to contact each other.
Although the organ resection tool of the present invention will be described with reference to the drawings, the present invention is not limited to the organ resection tool illustrated in the drawings.
（非伝導体接続刷毛状構造体を有する臓器切離具）
本発明の非伝導体接続刷毛状構造体を有する臓器切離具は、少なくとも、刷毛状構造体が直接的又は間接に絶縁体｛臓器切離具の先端（マイクロ波照射方向）の絶縁体：参照：図１５の「１１」、「１２」及び「１３」、図４の「７」及び図９の「１３」｝に接続していることを特徴として、少なくとも下記の構成を有する。
なお、下記の構成を有することにより、マイクロ波が特定の領域に集中的に照射することが可能になり、切離対象の組織以外の箇所にマイクロ波が印加されることを極力防ぐことができる。これにより、マイクロ波照射による正常組織の損傷を防ぐことができる。
(Organectomy tool with non-conductor-connected brush-like structure)
The organ resection tool having the non-conductor-connected brush-like structure of the present invention has at least the brush-like structure directly or indirectly as an insulator {insulator at the tip of the organ resection tool (microwave irradiation direction): Reference: It is connected to “11”, “12” and “13” in FIG. 15, “7” in FIG. 4 and “13” in FIG. 9}, and has at least the following configuration.
In addition, by having the following structure, it becomes possible to irradiate a specific area | region with a microwave intensively, and it can prevent applying a microwave to places other than the structure | tissue of separation object as much as possible. . Thereby, the damage of the normal tissue by microwave irradiation can be prevented.
以下の構成を含む非伝導体接続刷毛状構造体を有する臓器切離具１（実施態様１、参照：図１）。
（１）中空円柱形状の中心導体２。
（２）中心導体の内部の一部又は全部を埋める内部絶縁体３。
（３）中心導体の外部の一部又は全部を覆う中部絶縁体４。
（４）中部絶縁体４の一部又は全部を覆う外部導体５。
（５）内部絶縁体３に直接又は間接的に接続している刷毛状構造体６。
An organ resection tool 1 having a non-conductor-connected brush-like structure including the following configuration (Embodiment 1, reference: FIG. 1).
(1) A hollow cylindrical central conductor 2.
(2) An internal insulator 3 that fills part or all of the inside of the central conductor.
(3) The middle insulator 4 that covers part or all of the outside of the central conductor.
(4) An outer conductor 5 that covers part or all of the middle insulator 4.
(5) A brush-like structure 6 connected directly or indirectly to the internal insulator 3.
以下の構成を含む非伝導体接続刷毛状構造体を有する臓器切離具１（実施態様２、参照：図２）。
（１）中空円柱形状の中心導体２。
（２）中心導体の内部の一部又は全部を埋める内部絶縁体３。
（３）中心導体の外部の一部又は全部を覆う中部絶縁体４。
（４）中部絶縁体４の一部又は全部を覆う外部導体５。
（５）中部絶縁体４に直接又は間接的に接続している刷毛状構造体６。
An organ resection tool 1 having a non-conductor-connected brush-like structure including the following configuration (Embodiment 2, see: FIG. 2).
(1) A hollow cylindrical central conductor 2.
(2) An internal insulator 3 that fills part or all of the inside of the central conductor.
(3) The middle insulator 4 that covers part or all of the outside of the central conductor.
(4) An outer conductor 5 that covers part or all of the middle insulator 4.
(5) A brush-like structure 6 connected directly or indirectly to the middle insulator 4.
以下の構成を含む非伝導体接続刷毛状構造体を有する臓器切離具１（実施態様３、参照：図３）。
（１）中空円柱形状の中心導体２。
（２）中心導体の内部の一部又は全部を埋める内部絶縁体３。
（３）中心導体の外部の一部又は全部を覆う中部絶縁体４。
（４）中部絶縁体の一部又は全部を覆う外部導体５。
（５）内部絶縁体３及び中部絶縁体４に直接又は間接的に接続している刷毛状構造体６。
An organ resection tool 1 having a non-conductor-connected brush-like structure including the following configuration (Embodiment 3, see FIG. 3).
(1) A hollow cylindrical central conductor 2.
(2) An internal insulator 3 that fills part or all of the inside of the central conductor.
(3) The middle insulator 4 that covers part or all of the outside of the central conductor.
(4) An outer conductor 5 that covers a part or all of the middle insulator.
(5) A brush-like structure 6 connected directly or indirectly to the inner insulator 3 and the middle insulator 4.
以下の構成を含む非伝導体接続刷毛状構造体を有する臓器切離具１（実施態様４、参照：図４）。
（１）中空円柱形状の中心導体２。
（２）中心導体の内部の一部又は全部を埋める内部絶縁体３。
（３）中心導体の外部の一部又は全部を覆う中部絶縁体４。
（４）中部絶縁体の一部又は全部を覆う外部導体５。
（５）外部導体５の一部又は全部を覆う外部絶縁体７。
（６）内部絶縁体３、中部絶縁体４及び外部絶縁体７に直接又は間接的に接続している刷毛状構造体６。
An organ resection tool 1 having a non-conductor-connected brush-like structure including the following configuration (Embodiment 4, see FIG. 4).
(1) A hollow cylindrical central conductor 2.
(2) An internal insulator 3 that fills part or all of the inside of the central conductor.
(3) The middle insulator 4 that covers part or all of the outside of the central conductor.
(4) An outer conductor 5 that covers a part or all of the middle insulator.
(5) An external insulator 7 that covers part or all of the external conductor 5.
(6) A brush-like structure 6 connected directly or indirectly to the inner insulator 3, the middle insulator 4, and the outer insulator 7.
以下の構成を含む非伝導体接続刷毛状構造体を有する臓器切離具１（実施態様５、参照：図５）。
（１）マイクロ波印加用導体８。
（２）マイクロ波受手用導体９。
（３）マイクロ波印加用導体８とマイクロ波受手用導体９が略平行に位置しかつマイクロ波受手用導体９は、マイクロ波印加用導体８に対して臓器切離具１の先端断面１０の外側に位置し、両導体の４つの端で形成される領域の印加受手導体間絶縁体１１。
（４）印加受手導体間絶縁体１１に直接又は間接的に接続している刷毛状構造体６。
An organ resection tool 1 having a non-conductor-connected brush-like structure including the following configuration (Embodiment 5, see FIG. 5).
(1) Microwave application conductor 8.
(2) Microwave receiver conductor 9.
(3) The microwave application conductor 8 and the microwave receiver conductor 9 are positioned substantially parallel to each other, and the microwave receiver conductor 9 is cross-sectioned at the tip of the organ resection tool 1 with respect to the microwave application conductor 8. An insulator 11 between applied receiver conductors in a region located on the outer side of 10 and formed by four ends of both conductors.
(4) The brush-like structure 6 connected directly or indirectly to the insulator 11 between the application receiver conductors.
以下の構成を含む非伝導体接続刷毛状構造体を有する臓器切離具１（実施態様６、参照：図６、図１５）。
（１）マイクロ波印加用導体８。
（２）マイクロ波受手用導体９。
（３）２つ以上の印加受手導体間絶縁体１１。
（４）２つのマイクロ波印加用導体８間の４つの端で形成される領域の両導体間絶縁体１２。
（５）両導体間絶縁体１２に直接又は間接的に接続している刷毛状構造体６。
An organ resection tool 1 having a non-conductor-connected brush-like structure including the following configuration (Embodiment 6, see: FIGS. 6 and 15).
(1) Microwave application conductor 8.
(2) Microwave receiver conductor 9.
(3) Two or more application receiver insulators 11.
(4) The inter-conductor insulator 12 in the region formed by the four ends between the two microwave application conductors 8.
(5) The brush-like structure 6 connected directly or indirectly to the inter-conductor insulator 12.
以下の構成を含む非伝導体接続刷毛状構造体を有する臓器切離具１（実施態様７、参照：図７）。
（１）マイクロ波印加用導体８。
（２）マイクロ波受手用導体９。
（３）２つ以上の印加受手導体間絶縁体１１。
（４）両導体間絶縁体１２
（５）２つ以上の印加受手導体間絶縁体１１に直接又は間接的に接続している刷毛状構造体６。
An organ resection tool 1 having a non-conductor-connected brush-like structure including the following configuration (Embodiment 7, see FIG. 7).
(1) Microwave application conductor 8.
(2) Microwave receiver conductor 9.
(3) Two or more application receiver insulators 11.
(4) Insulator 12 between both conductors
(5) The brush-like structure 6 that is directly or indirectly connected to the two or more application receiver insulators 11.
以下の構成を含む非伝導体接続刷毛状構造体を有する臓器切離具１（実施態様８、参照：図８）。
（１）マイクロ波印加用導体８。
（２）マイクロ波受手用導体９。
（３）２つ以上の印加受手導体間絶縁体１１。
（４）両導体間絶縁体１２
（５）２つ以上の印加受手導体間絶縁体１１及び両導体間絶縁体１２に直接又は間接的に接続している刷毛状構造体６。
An organ resection tool 1 having a non-conductor-connected brush-like structure including the following configuration (Embodiment 8, see FIG. 8).
(1) Microwave application conductor 8.
(2) Microwave receiver conductor 9.
(3) Two or more application receiver insulators 11.
(4) Insulator 12 between both conductors
(5) The brush-like structure 6 that is directly or indirectly connected to the two or more application receiver inter-conductor insulators 11 and the inter-conductor insulators 12.
以下の構成を含む非伝導体接続刷毛状構造体を有する臓器切離具１（実施態様９、参照：図９）。
（１）マイクロ波印加用導体８。
（２）マイクロ波受手用導体９。
（３）２つ以上の印加受手導体間絶縁体１１。
（４）両導体間絶縁体１２。
（５）マイクロ波受手用導体９がマイクロ波印加用導体８とは反対側に形成される領域である外側絶縁体１３。
（６）２つ以上の印加受手導体間絶縁体１１、両導体間絶縁体１２及び外側絶縁体１３に直接又は間接的に接続している刷毛状構造体６。
An organ resection tool 1 having a non-conductor-connected brush-like structure including the following configuration (Embodiment 9, see: FIG. 9).
(1) Microwave application conductor 8.
(2) Microwave receiver conductor 9.
(3) Two or more application receiver insulators 11.
(4) The insulator 12 between both conductors.
(5) The outer insulator 13 which is a region where the microwave receiver conductor 9 is formed on the side opposite to the microwave applying conductor 8.
(6) The brush-like structure 6 connected directly or indirectly to the two or more application receiver inter-conductor insulators 11, the inter-conductor insulators 12, and the outer insulator 13.
（最適化刷毛状構造体を有する臓器切離具）
本発明の最適化刷毛状構造体を有する臓器切離具は、少なくとも、刷毛状構造体の配列設定、先端の被膜処理、又は先端のコーティング処理若しくはダイヤモンド研磨処理されていることを特徴として、少なくとも下記の構成を有する。
(Organectomy tool with optimized brush-like structure)
An organ resection tool having an optimized brush-like structure of the present invention is characterized in that at least the arrangement setting of the brush-like structure, the coating treatment of the tip, or the tip coating treatment or diamond polishing treatment is performed. It has the following configuration.
以下の構成（１）及び／又は（２）を含む最適化刷毛状構造体を有する臓器切離具。
（１）一列の直線状に配置されており、かつ、外部導体５又はマイクロ波受手用導体９に直接又は間接的に接続した複数の刷毛状構造体６（参照：図１３の「１５」）。
（２）一列の直線状に配置されており、かつ、中心導体２又はマイクロ波印加用導体８に直接又は間接的に接続した複数の刷毛状構造体６（参照：図１３の「１６」）。
なお、一列の直線状に配置された刷毛状構造体６の数は、特に限定されず、２〜１５本、好ましくは３〜１３本、より好ましくは４〜１０本である。
An organ resection tool having an optimized brush-like structure including the following configurations (1) and / or (2).
(1) A plurality of brush-like structures 6 arranged in a straight line and connected directly or indirectly to the outer conductor 5 or the microwave receiver conductor 9 (see: “15” in FIG. 13). ).
(2) A plurality of brush-like structures 6 arranged in a straight line and connected directly or indirectly to the central conductor 2 or the microwave application conductor 8 (see: “16” in FIG. 13). .
The number of the brush-like structures 6 arranged in a straight line is not particularly limited, and is 2 to 15, preferably 3 to 13, and more preferably 4 to 10.
以下の構成を含む最適化刷毛状構造体を有する臓器切離具１（実施態様１０、参照：図１２）。
外部導体５又はマイクロ波受手用導体９に直接又は間接的に接続した複数の刷毛状構造体６並びに中心導体２又はマイクロ波印加用導体８に直接又は間接的に接続した複数の刷毛状構造体６が、直線状の一列に配置されている（参照：図１２の「１７」）。
An organ resection tool 1 having an optimized brush-like structure including the following configuration (Embodiment 10, see FIG. 12).
A plurality of brush-like structures 6 directly or indirectly connected to the outer conductor 5 or the microwave receiver conductor 9 and a plurality of brush-like structures directly or indirectly connected to the center conductor 2 or the microwave applying conductor 8 The bodies 6 are arranged in a straight line (refer to “17” in FIG. 12).
以下の構成を含む最適化刷毛状構造体を有する臓器切離具１（実施態様１１、参照：図１３、１６）。
外部導体５又はマイクロ波受手用導体９に直接又は間接的に接続した複数の刷毛状構造体６が直線状の一列に配置されており（参照：図１３、１６の「１５」）、並びに、中心導体２又はマイクロ波印加用導体８に直接又は間接的に接続した複数の刷毛状構造体６が直線状の一列に配置されており（参照：図１３、１６の「１６」）、さらに好ましくはそれらの２列が略平行である（参照：図１３の「１８」）。
好ましい態様としては、複数の刷毛状構造体６は、刷毛台２１を介して、外部導体５又はマイクロ波受手用導体９に接続している。同様に、複数の刷毛状構造体６は、刷毛台２１を介して、中心導体２又はマイクロ波印加用導体８に接続している。
An organ resection tool 1 having an optimized brush-like structure including the following configuration (Embodiment 11, see: FIGS. 13 and 16).
A plurality of brush-like structures 6 directly or indirectly connected to the outer conductor 5 or the microwave receiver conductor 9 are arranged in a straight line (refer to “15” in FIGS. 13 and 16), and A plurality of brush-like structures 6 connected directly or indirectly to the central conductor 2 or the microwave application conductor 8 are arranged in a straight line (see: “16” in FIGS. 13 and 16), and Preferably, the two rows are substantially parallel (see: “18” in FIG. 13).
As a preferred embodiment, the plurality of brush-like structures 6 are connected to the external conductor 5 or the microwave receiver conductor 9 via the brush base 21. Similarly, the plurality of brush-like structures 6 are connected to the central conductor 2 or the microwave application conductor 8 via the brush base 21.
以下の構成を含む最適化刷毛状構造体を有する臓器切離具１（実施態様１２、参照：図１０、図１１）。
上記述べた臓器切離具１の刷毛状構造体６が、絶縁材料１４で被覆されている。
An organ resection tool 1 having an optimized brush-like structure including the following configuration (embodiment 12, see: FIGS. 10 and 11).
The brush-like structure 6 of the organ resection tool 1 described above is covered with an insulating material 14.
以下の構成を含む最適化刷毛状構造体を有する臓器切離具１。
上記述べた臓器切離具１の刷毛状構造体６の先端がフッ素系コーティング処理、シリコン系コーディング処理、又はダイヤモンド研磨処理されている。
An organ resection tool 1 having an optimized brush-like structure including the following configuration.
The tip of the brush-like structure 6 of the organ resection tool 1 described above is subjected to fluorine coating treatment, silicon coding treatment, or diamond polishing treatment.
（刷毛状構造体及び補助手段を有する臓器切離具）
本発明の刷毛状構造体及び補助手段を有する臓器切離具は、少なくとも、刷毛状構造体の先端が左右交互又は一方向に回転動作可能であるように導入する、並びに、振動機能手段及び／又は吸引機能手段を導入したことを特徴として、少なくとも下記の構成を有する。
(An organ resection tool having a brush-like structure and auxiliary means)
An organ resection tool having a brush-like structure and auxiliary means of the present invention is introduced so that at least the tip of the brush-like structure can be rotated left and right alternately or in one direction, and vibration function means and / or Or it has at least the following structure, characterized by introducing suction function means.
以下の構成を含む刷毛状構造体及び補助手段を有する臓器切離具１（実施態様１３）。
上記述べた臓器切離具１の刷毛状構造体６の先端が右左交互又は一方向に回転動作する。回転動作する動力（機構）は、自体工程のモータ等を臓器切離具１の内部に内蔵することにより可能である。
刷毛状構造体６の先端が右左交互又は一方向に回転動作することが出来るようになり、狭視下でも容易にマイクロ波を印加でき、さらに印加された組織を除去（掻き取る）ことができるので、固着物（組織破片）の除去が容易にできる。
An organ resection tool 1 (embodiment 13) having a brush-like structure including the following configuration and auxiliary means.
The tip of the brush-like structure 6 of the organ resection tool 1 described above rotates right or left alternately or in one direction. The rotating power (mechanism) is possible by incorporating a motor or the like for the process itself in the organ resection tool 1.
The tip of the brush-like structure 6 can rotate right and left alternately or in one direction, so that microwaves can be easily applied even under narrow vision, and the applied tissue can be removed (scraped). Therefore, it is possible to easily remove the fixed matter (tissue fragments).
以下の構成を含む刷毛状構造体及び補助手段を有する臓器切離具１（実施態様１４）。
上記述べた臓器切離具１が、振動機能手段を有し、刷毛状構造体６の先端が振動する。
An organ resection tool 1 (embodiment 14) having a brush-like structure and auxiliary means including the following configuration.
The organ resection tool 1 described above has vibration function means, and the tip of the brush-like structure 6 vibrates.
（振動機能手段）
刷毛状構造体６は、振動機能手段と連動することも可能である。例えば、刷毛状構造体に繋がる持ち手部は、振動発振器に繋がり、携帯又は据置型本体からの振動発振であっても良い。振動機能手段は、高周波振動子又は超音波振動子であっても良いが、キャビテーションを起こす振動数が望ましい。振動子は、超音波を発生させるための超音波振動子と、前記超音波振動子において発生した超音波を、対象物に刷毛状構造体６を経て伝達する。
臓器切離具１が、振動機能手段を有することにより、狭視下でも容易にマイクロ波を印加でき、さらに印加された組織を除去（掻き取る）ことができるので、固着物（組織破片）の除去が容易にできる。
(Vibration function means)
The brush-like structure 6 can also be interlocked with vibration function means. For example, the handle portion connected to the brush-like structure may be connected to a vibration oscillator and may be vibration oscillation from a portable or stationary main body. The vibration function means may be a high-frequency vibrator or an ultrasonic vibrator, but preferably has a frequency that causes cavitation. The vibrator transmits an ultrasonic vibrator for generating an ultrasonic wave and the ultrasonic wave generated by the ultrasonic vibrator to the object through the brush-like structure 6.
Since the organ resection tool 1 has vibration function means, microwaves can be easily applied even under narrow vision, and the applied tissue can be removed (scraped). Easy to remove.
以下の構成を含む刷毛状構造体及び補助手段を有する臓器切離具１（実施態様１５、参照：図１４）。
上記述べた臓器切離具１が、吸引機能手段１９を有する。
吸引機能手段１９は、自体公知を利用することができるが、例えば、細胞の破片を吸引可能な口径を有する吸引口を有するパイプであり、さらに該破片を吸引するために吸引ポンプに連結している。さらに、必要に応じて、水の注入ができることが好ましい。
臓器切離具１が、吸引機能手段１９を有することにより、固着物（組織破片）を自動で吸引除去できる。これにより、手術者は、固着物の除去のためにマイクロ波印加又は組織の除去作業を中断する必要がない。
An organ resection tool 1 having a brush-like structure and auxiliary means including the following configuration (Embodiment 15, see FIG. 14).
The organ resection tool 1 described above has a suction function means 19.
The suction function means 19 can be known per se. For example, the suction function means 19 is a pipe having a suction port having a diameter capable of sucking cell debris, and is connected to a suction pump to suck the debris. Yes. Furthermore, it is preferable that water can be injected as needed.
Since the organ resection tool 1 has the suction function means 19, the fixed matter (tissue debris) can be sucked and removed automatically. This eliminates the need for the operator to interrupt the microwave application or tissue removal operation to remove the adherent.
（マイクロ照射機能）
本発明のマイクロ波照射機能（手段）は、好ましくは、マイクロ波伝送部及びプローベを含む。マイクロ波伝送部は、中心導体、絶縁体及び外部導体を含む場合には、中心導体、絶縁体及び外部導体が同軸状に備わる同軸ケーブルを形成し、又は、マイクロ波印加用導体、マイクロ波受手用導体及び絶縁体を含む場合には、４角柱形状のマイクロ波印加用導体と４角柱形状のマイクロ波受手用導体が絶縁体を介して接触しないように形成されている（以後、「マイクロ波印加受手構造」と称する）。
なお、マイクロ波は、９００〜６０００ＭＨｚのものが同等に利用可能である。好ましくは２４５０±５０ＭＨｚである。
また、本発明で用いられる同軸ケーブル又はマイクロ波印加受手構造は、直接的又は間接的（別の同軸ケーブルを介して）にマイクロ波照射装置に接続されている。
本発明で使用するマイクロ波照射装置は、小電力で処置を可能とし、安全性にも優れている。本発明において使用される電力は１Ｗ〜１００Ｗ、好ましくは５Ｗ〜６０Ｗである。さらに好ましくは１０Ｗ〜４０Ｗである。電力の強さは露出部の長さにより調整できる。
(Micro irradiation function)
The microwave irradiation function (means) of the present invention preferably includes a microwave transmission unit and a probe. When the microwave transmission unit includes a center conductor, an insulator, and an outer conductor, the microwave transmission unit forms a coaxial cable in which the center conductor, the insulator, and the outer conductor are provided coaxially, or a microwave application conductor, a microwave receiver In the case of including a hand conductor and an insulator, the quadrangular prism-shaped microwave application conductor and the quadrangular prism-shaped microwave receiver conductor are formed so as not to contact each other via the insulator (hereinafter, “ Called microwave application receiver structure).
Note that a microwave of 900 to 6000 MHz can be used equally. Preferably, it is 2450 ± 50 MHz.
Further, the coaxial cable or the microwave application receiver structure used in the present invention is connected to the microwave irradiation device directly or indirectly (via another coaxial cable).
The microwave irradiation apparatus used in the present invention can be treated with low power and is excellent in safety. The electric power used in the present invention is 1 W to 100 W, preferably 5 W to 60 W. More preferably, it is 10W-40W. The strength of the electric power can be adjusted by the length of the exposed portion.
（同軸ケーブル又はマイクロ波印加受手構造）
同軸ケーブル又はマイクロ波印加受手構造を軟性にすることにより、本発明の臓器切離操作具１は、内視鏡及び／又はカテーテルに挿入可能である。開腹手術など、直視下での手術では、好ましくは手術者が把持するために絶縁体からなる把持部を有する。
本発明で用いられる同軸ケーブル又はマイクロ波印加受手構造は、例えば、リン青銅からなる導電体の中心導体（マイクロ波印加用導体）と、中心導体を覆う例えばテフロン（登録商標）からなる絶縁体のシールドチューブと、例えば真鍮からなる外部導体（マイクロ波受手用導体）のアースパイプからなる。同軸ケーブルのその外側はシールドホルダ（ガイドチューブともいう）で覆われていてもよい。シールドホルダは、非伝導性部材〔例えば、テフロン（登録商標）、フッ素樹脂、セラミック等の非磁性のコイル〕で構成されていることが好ましい。
好ましい同軸体の直径は０．３〜５．０ｍｍである。
本発明の同軸ケーブル（マイクロ波印加受手構造）の中心導体（マイクロ波印加用導体）の材質は、銅、青銅、アルミ等が例示され、絶縁体の材質は、テフロン（登録商標）、セラミック等が例示される。外部導体（マイクロ波受手用導体）は導電体であれば特に限定されない。
(Coaxial cable or microwave application receiver structure)
By making the coaxial cable or the microwave application receiver structure soft, the organ resection tool 1 of the present invention can be inserted into an endoscope and / or a catheter. In surgery under direct vision such as laparotomy, the operator preferably has a grip portion made of an insulator for gripping.
The coaxial cable or microwave application receiver structure used in the present invention includes, for example, a conductor central conductor (microwave application conductor) made of phosphor bronze and an insulator made of Teflon (registered trademark) covering the center conductor, for example. And an earth pipe of an outer conductor (a microwave receiver conductor) made of, for example, brass. The outside of the coaxial cable may be covered with a shield holder (also referred to as a guide tube). The shield holder is preferably made of a non-conductive member [for example, non-magnetic coil such as Teflon (registered trademark), fluororesin, ceramic, or the like].
A preferable coaxial body has a diameter of 0.3 to 5.0 mm.
The material of the central conductor (microwave application conductor) of the coaxial cable (microwave application receiver structure) of the present invention is exemplified by copper, bronze, aluminum, etc. The insulator material is Teflon (registered trademark), ceramic Etc. are exemplified. The outer conductor (microwave receiver conductor) is not particularly limited as long as it is a conductor.
（刷毛状構造体）
本発明の臓器切離操作具１において、刷毛状構造体６は、大きく２つに分かれる。刷毛状構造体６が中心導体、マイクロ波印加用導体、外部導体又はマイクロ波受手用導体に直接又は間接的に接続している場合には、該刷毛状構造体はマイクロ波照射可能な材質に限定される。しかし、刷毛状構造体６が絶縁体に直接又は間接的に接続している場合には、該刷毛状構造体はマイクロ波照射可能な材質に限定されない。
いずれの刷毛状構造体６でも、臓器を掻き取り（生体組織に圧を与える）のための刷毛状であり、臓器との接触する部分である。
(Brush-like structure)
In the organ resection tool 1 of the present invention, the brush-like structure 6 is roughly divided into two. When the brush-like structure 6 is directly or indirectly connected to the central conductor, the microwave application conductor, the external conductor, or the microwave receiver conductor, the brush-like structure is a material that can be irradiated with microwaves. It is limited to. However, when the brush-like structure 6 is directly or indirectly connected to the insulator, the brush-like structure is not limited to a material that can be irradiated with microwaves.
Any of the brush-like structures 6 is a brush-like shape for scraping off an organ (applying pressure to a living tissue) and is a portion in contact with the organ.
（マイクロ波照射可能な材質に限定されない刷毛状構造体）
マイクロ波照射可能な材質に限定されない刷毛状構造体は、マイクロ波照射可能な材質であっても良いが、好ましくは、先端の被膜処理、又は先端のコーティング処理若しくはダイヤモンド研磨処理することが可能である材質が好ましい。
刷毛状構造体６の刷毛の径は、φ0.1mm〜φ1.0mmの範囲が好ましい。刷毛状構造体６の刷毛の長さは、2.0mm〜30.0mmの範囲が好ましい。刷毛状構造体６の刷毛の総本数は1本〜30本の範囲が好ましい。刷毛状構造体６の各刷毛の配置範囲（密度）は、半径10.0mm以内が好ましい。刷毛状構造体６の刷毛素材のヤング率は100〜220Gpa（黄銅：100GPa、鋼：200〜215GPaを参考に設定した場合）の範囲が好ましい。
上記のように刷毛の径、長さ、密度、総本数及びヤング率のいずれか２以上、好ましくは３以上を採用することにより、様々な臓器（特に、実質臓器）の硬さに対応することができるので、臓器の切離が容易に達成することができる。
刷毛状構造体６の絶縁体（３，４，７、１３）の接合部から先端近傍を、絶縁材料（フッ素樹脂、シリコン樹脂）で被覆する（厚膜1mm〜5mm）。この被膜により、固着物（臓器破片）の除去が容易にできる。
刷毛状構造体６の全体に1μm〜100μm厚膜のフッ素、シリコンコーティング又はダイヤモンド研磨処理を行う。これらにより、臓器破片（組織）の固着防止をすることができる。
(Brush-like structure not limited to materials that can be irradiated with microwaves)
The brush-like structure that is not limited to a material that can be irradiated with microwaves may be a material that can be irradiated with microwaves, but is preferably capable of being subjected to coating treatment at the tip, coating treatment at the tip, or diamond polishing treatment. Some materials are preferred.
The diameter of the brush of the brush-like structure 6 is preferably in the range of φ0.1 mm to φ1.0 mm. The length of the brush of the brush-like structure 6 is preferably in the range of 2.0 mm to 30.0 mm. The total number of brushes of the brush-like structure 6 is preferably in the range of 1 to 30. The arrangement range (density) of each brush in the brush-like structure 6 is preferably within a radius of 10.0 mm. The Young's modulus of the brush material of the brush-like structure 6 is preferably in the range of 100 to 220 GPa (when brass is set to 100 GPa and steel is set to 200 to 215 GPa for reference).
By adopting any 2 or more, preferably 3 or more, of the diameter, length, density, total number and Young's modulus of the brush as described above, it is possible to cope with the hardness of various organs (particularly, the real organ). Therefore, organ resection can be easily achieved.
The vicinity of the tip from the joint portion of the insulator (3, 4, 7, 13) of the brush-like structure 6 is covered with an insulating material (fluororesin, silicon resin) (thick film 1 mm to 5 mm). With this coating, it is possible to easily remove the fixed matter (organ debris).
The entire brush-like structure 6 is subjected to a 1 μm to 100 μm thick fluorine, silicon coating or diamond polishing process. As a result, organ debris (tissue) can be prevented from sticking.
刷毛状構造体６の形状は、臓器を痛めない形状であり、柔らかく、弾性があり、先端が細く（先細り）かつしなやかに曲がる形状にすることもでき、このような形状は、毛細管現象を起こすこともできる。
これらの形状は、国際公開2010/143384号公報を参照することができる。
The shape of the brush-like structure 6 is a shape that does not damage the organ, and is soft and elastic, and the tip can be thin (tapered) and can be bent flexibly. Such a shape causes capillary action. You can also
Reference can be made to International Publication No. 2010/143384 for these shapes.
（マイクロ波照射可能な材質の刷毛状構造体）
マイクロ波照射可能な材質の刷毛状構造体６は、マイクロ波照射可能及び／又はマイクロ波の受け手となることが可能な材質であれば特に、限定されない。
例えば、鉄、銅、チタン、ステンレス、リン青銅又は真鍮製等広く導電性材料が使用可能である。好適には、リン青銅、ステンレス、真鍮等が例示される。
(Brush-like structure made of materials that can be irradiated with microwaves)
The brush-like structure 6 made of a material that can be irradiated with microwaves is not particularly limited as long as it is a material that can be irradiated with microwaves and / or can be a receiver of microwaves.
For example, a wide range of conductive materials such as iron, copper, titanium, stainless steel, phosphor bronze, or brass can be used. Preferable examples include phosphor bronze, stainless steel and brass.
以下に具体例を挙げて本発明の臓器切離操作具を詳細に説明するが、本発明はこれらの例に限定されない。 The organ resection tool of the present invention will be described in detail below with specific examples, but the present invention is not limited to these examples.
（非伝導体接続刷毛状構造体を有する臓器切離具）
本発明の非伝導体接続刷毛状構造体を有する臓器切離具の特性を確認した。より詳しくは、動物（犬、豚）の肝臓（実質臓器）を対象とした切除実験を実施した。
(Organectomy tool with non-conductor-connected brush-like structure)
The characteristics of the organ resection tool having the non-conductor-connected brush-like structure of the present invention were confirmed. More specifically, an excision experiment was performed on the liver (parenchymal organ) of an animal (dog, pig).
実施態様１（参照：図１）の臓器切離具１を用いた。 The organ resection tool 1 according to Embodiment 1 (see FIG. 1) was used.
（非伝導体接続刷毛状構造体を有する臓器切離具の効果の確認）
実施態様１の臓器切離具１の非伝導体接続刷毛状構造体６では、マイクロ波が特定の領域に集中的に照射することが可能になり、切離対象の組織以外の箇所にマイクロ波が印加されることを極力防ぐことができた。これにより、マイクロ波照射による正常組織の損傷を防ぐことができた。
さらに、刷毛状構造体６の特性により、様々な臓器（特に、実質臓器）の硬さに対応することができた。
(Confirmation of effects of organ resection tool with non-conductor-connected brush-like structure)
In the non-conductor-connected brush-like structure 6 of the organ resection tool 1 according to the first embodiment, it becomes possible to irradiate a specific area with microwaves intensively, and the microwave is applied to a place other than the tissue to be separated. Can be prevented as much as possible. As a result, damage to normal tissue due to microwave irradiation could be prevented.
Furthermore, due to the characteristics of the brush-like structure 6, it was possible to cope with the hardness of various organs (particularly, the real organs).
（最適化刷毛状構造体を有する臓器切離具）
本発明の最適化刷毛状構造体を有する臓器切離具の特性を確認した。より詳しくは、動物（犬、豚）の肝臓（実質臓器）を対象とした切除実験を実施した。
(Organectomy tool with optimized brush-like structure)
The characteristics of the organ resection tool having the optimized brush-like structure of the present invention were confirmed. More specifically, an excision experiment was performed on the liver (parenchymal organ) of an animal (dog, pig).
実施態様１０（参照：図１２）の臓器切離具１及び実施態様１１（参照：図１３）の臓器切離具１を用いた。
さらに、刷毛状構造体６の絶縁体の接合部から先端近傍を、絶縁材料（シリコン樹脂）で被覆（厚膜1mm〜5mm）した。
刷毛状構造体６の特性は、以下の通りである。
○刷毛の径：φ0.1mm〜φ1.0mm
○刷毛の長さ：2.0mm〜30.0mm
○刷毛の密度：半径10.0mm以内
○刷毛の総本数：1本〜30本
○ヤング率：100〜220Gpa
The organ resection tool 1 of Embodiment 10 (Reference: FIG. 12) and the organ resection tool 1 of Embodiment 11 (Reference: FIG. 13) were used.
Further, the vicinity of the tip from the joint portion of the insulator of the brush-like structure 6 was covered with an insulating material (silicon resin) (thick film 1 mm to 5 mm).
The characteristics of the brush-like structure 6 are as follows.
○ Brush diameter: φ0.1mm to φ1.0mm
○ Brush length: 2.0mm to 30.0mm
○ Brush density: within radius of 10.0mm ○ Total number of brushes: 1 to 30 ○ Young's modulus: 100 to 220Gpa
（最適化刷毛状構造体を有する臓器切離具の効果の確認）
実施態様１０の臓器切離具１の刷毛状構造体６では、刷毛が一列に配置していることにより、一列配置した刷毛先端が均等に手術部に接触し、マイクロ波による止血と同時に擦過できた。
実施態様１１の臓器切離具１の刷毛状構造体６では、刷毛が二列に配置していることにより、二列配置した刷毛先端が均等に手術部に接触し、マイクロ波による止血と同時に擦過できた。
さらに、実施態様１０の臓器切離具１及び実施態様１１の臓器切離具１に関し、刷毛状構造体６の絶縁体の接合部から先端近傍がシリコン樹脂で被膜されていることにより、固着物（臓器破片）の除去が容易にすることができた。
さらに、以下の点を確認した。
○止血・擦過操作が、従来の臓器切離具と比較して、容易に行うことができた。
○太い血管を残しながらの細かな操作ができた。
○擦過された手術部の組織固着物をガーゼで容易に取り除くことができた。
○切離操作が、従来の臓器切離具と比較して、容易に行うことができた。
(Confirmation of effect of organ resection tool with optimized brush-like structure)
In the brush-like structure 6 of the organ resection tool 1 according to the tenth embodiment, since the brushes are arranged in a row, the brush tips arranged in a row can evenly contact the surgical site, and can be scraped simultaneously with hemostasis by microwaves. It was.
In the brush-like structure 6 of the organ resection tool 1 according to the eleventh embodiment, since the brushes are arranged in two rows, the tips of the brushes arranged in two rows are in uniform contact with the surgical site, and simultaneously with hemostasis by microwaves. I was able to rub it.
Furthermore, regarding the organ resection tool 1 according to the tenth embodiment and the organ resection tool 1 according to the eleventh embodiment, the vicinity of the tip from the joint portion of the insulator of the brush-like structure 6 is coated with silicon resin, so that a fixed object is obtained. Removal of (organ debris) could be facilitated.
Furthermore, the following points were confirmed.
○ Hemostasis and scratching operations were easily performed compared to conventional organ resection tools.
○ Detailed operations were possible while leaving thick blood vessels.
○ The tissue fixed matter of the surgical site that was abraded could be easily removed with gauze.
○ The excision operation could be easily performed compared with the conventional organ resection tool.
（刷毛状構造体及び補助手段を有する臓器切離具）
本発明の刷毛状構造体及び補助手段を有する臓器切離具の特性を確認した。より詳しくは、動物（犬、豚）の肝臓（実質臓器）を対象とした切除実験を実施した。
(An organ resection tool having a brush-like structure and auxiliary means)
The characteristics of the organ resection tool having the brush-like structure and auxiliary means of the present invention were confirmed. More specifically, an excision experiment was performed on the liver (parenchymal organ) of an animal (dog, pig).
実施態様１５（参照：図１４）の臓器切離具１を使用した。実施態様１５の臓器切離具１は、吸引機能手段１９を有する。
刷毛状構造体６の特性は、以下の通りである。
○刷毛の径：φ0.1mm〜φ1.0mm
○刷毛の長さ：2.0mm〜30.0mm
○刷毛の密度：半径10.0mm以内
○刷毛の総本数：1本〜30本
○ヤング率：100〜220Gpa
また、吸引機能手段１９は、支持台２０を貫通し、かつ細胞の破片を吸引可能な口径を有する吸引口を有するパイプである。さらに、吸引ポンプが該パンプに連結している。
The organ resection tool 1 according to Embodiment 15 (see FIG. 14) was used. The organ resection tool 1 according to the fifteenth embodiment has a suction function means 19.
The characteristics of the brush-like structure 6 are as follows.
○ Brush diameter: φ0.1mm to φ1.0mm
○ Brush length: 2.0mm to 30.0mm
○ Brush density: within radius of 10.0mm ○ Total number of brushes: 1 to 30 ○ Young's modulus: 100 to 220Gpa
The suction function means 19 is a pipe having a suction port that penetrates the support base 20 and has a diameter capable of sucking cell debris. Furthermore, a suction pump is connected to the pump.
（刷毛状構造体及び補助手段を有する臓器切離具の効果の確認）
実施態様１５の臓器切離具１では、刷毛状構造体６に固着した臓器破片が吸引機能手段１９の吸引パイプ内に取り込まれた（自動で吸引除去された）。これにより、手術者（実験者）は、固着物の除去のためにマイクロ波印加又は組織の除去作業を中断する必要がなかった。
(Confirmation of effects of organ resection tool with brush-like structure and auxiliary means)
In the organ resection tool 1 according to the fifteenth embodiment, organ debris fixed to the brush-like structure 6 was taken into the suction pipe of the suction function means 19 (automatically removed by suction). Thereby, the operator (experimenter) did not need to interrupt the microwave application or the tissue removal operation for removing the fixed matter.
（総論）
以上により、本発明の臓器切離具１（非伝導体接続刷毛状構造体を有する臓器切離具、最適化刷毛状構造体を有する臓器切離具及び刷毛状構造体及び補助手段を有する臓器切離具）では、以下の効果を有する。
（非伝導体接続刷毛状構造体及び／又は最適化刷毛状構造体を有する臓器切離具）
○刷毛への固着除去効果が向上し、手術時間の短縮となる。
○刷毛形状の改良により操作性が向上し、太い血管を残しながらの擦過操作や切離操作が可能となる。
○様々な臓器（特に、実質臓器）の硬さに対応することができるので、臓器の切離が容易に達成することができる。
○肝硬変等の固い組織を破砕することが可能となる。
○マイクロ波が特定の領域に集中的に照射することが可能になり、切離対象の組織以外の箇所にマイクロ波が印加されることを極力防ぐことができる。これにより、マイクロ波照射により正常組織の損傷を防ぐことができる。
(General)
As described above, the organ resection tool 1 of the present invention (an organ resection tool having a non-conductor-connected brush-like structure, an organ resection tool having an optimized brush-like structure, a brush-like structure, and an organ having auxiliary means) The cutting tool has the following effects.
(Non-conductor-connected brush-like structure and / or organ resection tool with optimized brush-like structure)
○ The effect of removing the sticking to the brush is improved and the operation time is shortened.
○ The operability is improved by improving the brush shape, and the rubbing operation and the separation operation can be performed while leaving a thick blood vessel.
○ Since it is possible to cope with the hardness of various organs (particularly, real organs), organ separation can be easily achieved.
○ Hard tissue such as cirrhosis can be crushed.
O It becomes possible to irradiate a specific area with a microwave in a concentrated manner, and it is possible to prevent the microwave from being applied to a portion other than the tissue to be separated as much as possible. Thereby, damage of normal tissue can be prevented by microwave irradiation.
（刷毛状構造体及び補助手段を有する臓器切離具）
○擦過や切離が困難であった神経や多臓器の入り組んだ部分の手術が容易になる。
○刷毛を振動させる又は回転させることにより固着物が該刷毛から容易に除去することができる。
○手術者が、鏡視下において、刷毛の先端を左右上下の動作をすることなく擦過操作を行うことができる。
(An organ resection tool having a brush-like structure and auxiliary means)
○ Surgery of complicated parts of nerves and multiple organs that were difficult to scrape and separate.
O Fixed matter can be easily removed from the brush by vibrating or rotating the brush.
O The surgeon can perform a rubbing operation without performing left and right and up and down movements of the tip of the brush under a mirror.
本発明では、新規かつ有用な臓器切離具を提供することができる。 In the present invention, a novel and useful organ resection tool can be provided.
１：臓器切離具
２：中心導体
３：内部絶縁体
４：中部絶縁体
５：外部導体
６：刷毛状構造体
７：外部絶縁体
８：マイクロ波印加用導体
９：マイクロ波受手用導体
１０：先端断面
１１：印加受手導体間絶縁体
１２：両導体間絶縁体
１３：外側絶縁体
１４：絶縁材料
１５：一列の直線状に配置されており、かつ、外部導体又はマイクロ波受手用導体に直接又は間接的に接続した複数の刷毛状構造体
１６：一列の直線状に配置されており、かつ、中心導体又はマイクロ波印加用導体に直接又は間接的に接続した複数の刷毛状構造体
１７：一列に配置されている「外部導体又はマイクロ波受手用導体に直接又は間接的に接続した複数の刷毛状構造体並びに中心導体又はマイクロ波印加用導体に直接又は間接的に接続した複数の刷毛状構造体」。
１８：直線状の２列に配置されている「一列の直線状に配置されており、かつ、外部導体５又はマイクロ波受手用導体に直接又は間接的に接続した複数の刷毛状構造体」並びに「一列の直線状に配置されており、かつ、中心導体又はマイクロ波印加用導体に直接又は間接的に接続した複数の刷毛状構造体」
１９：吸引機能手段
２０：支持台
２１：刷毛台
1: Organ resection tool 2: Center conductor 3: Internal insulator 4: Middle insulator 5: External conductor 6: Brush-like structure 7: External insulator 8: Microwave application conductor 9: Microwave receiver conductor 10: Cross-section of tip 11: Insulator between applied receivers 12: Insulator between both conductors 13: Outer insulator 14: Insulating material 15: Arranged in a straight line and external conductor or microwave receiver A plurality of brush-like structures 16 directly or indirectly connected to a conductor for use, and a plurality of brush-like structures arranged in a straight line and connected directly or indirectly to a central conductor or a microwave application conductor Structure 17: “A plurality of brush-like structures directly or indirectly connected to the outer conductor or the microwave receiver conductor and the central conductor or the microwave application conductor, which are arranged in a row, directly or indirectly. Multiple brush-like structures "
18: “A plurality of brush-like structures arranged in a straight line and connected directly or indirectly to the outer conductor 5 or the microwave receiver conductor” arranged in two straight lines And "a plurality of brush-like structures that are arranged in a straight line and are directly or indirectly connected to the central conductor or the microwave application conductor".
19: Suction function means 20: Support stand 21: Brush stand
Claims (19)
（１）中心導体又はマイクロ波印加用導体
（２）外部導体又はマイクロ波受手用導体
（３）該中心導体、該マイクロ波印加用導体、該外部導体又は該マイクロ波受手用導体の一部又は全部を覆う絶縁体
（４）該絶縁体に直接又は間接的に接続している刷毛状構造体、又は、該中心導体、該マイクロ波印加用導体、該外部導体又は該マイクロ波受手用導体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
An organ resection tool including the following configuration,
(1) Center conductor or microwave application conductor (2) Outer conductor or microwave receiver conductor (3) One of the center conductor, microwave application conductor, outer conductor or microwave receiver conductor Insulator covering part or all (4) Brush-like structure directly or indirectly connected to the insulator, or the central conductor, the microwave applying conductor, the external conductor or the microwave receiver A brush-like structure connected directly or indirectly to the conductor for
Organ resection tool.
（１）前記中心導体は中空円柱形状の中心導体であり、
（２）該中心導体の内部の一部又は全部を埋める内部絶縁体
（３）該中心導体の外部の一部又は全部を覆う中部絶縁体、
（４）該中部絶縁体の一部又は全部を覆う外部導体、及び
（５）該内部絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
The organ resection tool according to claim 1, comprising the following configuration:
(1) The central conductor is a hollow cylindrical central conductor,
(2) An internal insulator that fills part or all of the inside of the central conductor (3) A middle insulator that covers part or all of the outside of the central conductor,
(4) including an outer conductor covering a part or all of the middle insulator, and (5) a brush-like structure directly or indirectly connected to the inner insulator.
Organ resection tool.
（１）前記中心導体は中空円柱形状の中心導体であり、
（２）該中心導体の内部の一部又は全部を埋める内部絶縁体
（３）該中心導体の外部の一部又は全部を覆う中部絶縁体、
（４）該中部絶縁体の一部又は全部を覆う外部導体、及び
（５）該中部絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
The organ resection tool according to claim 1, comprising the following configuration:
(1) The central conductor is a hollow cylindrical central conductor,
(2) An internal insulator that fills part or all of the inside of the central conductor (3) A middle insulator that covers part or all of the outside of the central conductor,
(4) an outer conductor covering a part or all of the middle insulator, and (5) a brush-like structure directly or indirectly connected to the middle insulator.
Organ resection tool.
（１）前記中心導体は中空円柱形状の中心導体であり、
（２）該中心導体の内部の一部又は全部を埋める内部絶縁体
（３）該中心導体の外部の一部又は全部を覆う中部絶縁体、
（４）該中部絶縁体の一部又は全部を覆う外部導体、及び
（５）該内部絶縁体及び該中部絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
The organ resection tool according to claim 1, comprising the following configuration:
(1) The central conductor is a hollow cylindrical central conductor,
(2) An internal insulator that fills part or all of the inside of the central conductor (3) A middle insulator that covers part or all of the outside of the central conductor,
(4) an outer conductor covering part or all of the middle insulator, and (5) a brush-like structure directly or indirectly connected to the inner insulator and the middle insulator.
Organ resection tool.
（１）前記中心導体は中空円柱形状の中心導体であり、
（２）該中心導体の内部の一部又は全部を埋める内部絶縁体
（３）該中心導体の外部の一部又は全部を覆う中部絶縁体、
（４）該中部絶縁体の一部又は全部を覆う外部導体、
（５）該外部導体の一部又は全部を覆う外部絶縁体、及び
（６）該内部絶縁体、該中部絶縁体及び該外部絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
The organ resection tool according to claim 1, comprising the following configuration:
(1) The central conductor is a hollow cylindrical central conductor,
(2) An internal insulator that fills part or all of the inside of the central conductor (3) A middle insulator that covers part or all of the outside of the central conductor,
(4) an outer conductor covering part or all of the middle insulator;
(5) an external insulator covering part or all of the outer conductor, and (6) a brush-like structure directly or indirectly connected to the inner insulator, the middle insulator, and the outer insulator, including,
Organ resection tool.
（１）前記マイクロ波印加用導体、
（２）前記マイクロ波受手用導体、
（３）該マイクロ波印加用導体と該マイクロ波受手用導体が略平行に位置しかつ該マイクロ波受手用導体は、該マイクロ波印加用導体に対して該切離具の先端断面の外側に位置し、両導体の４つの端で形成される領域の印加受手導体間絶縁体、及び
（４）該印加受手導体間絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
The organ resection tool according to claim 1, comprising the following configuration:
(1) The microwave application conductor,
(2) the microwave receiver conductor;
(3) The microwave application conductor and the microwave receiver conductor are positioned substantially in parallel, and the microwave receiver conductor has a cross-section of the tip of the cutting tool with respect to the microwave application conductor. An insulator between applied receiver conductors in a region located on the outside and formed by four ends of both conductors; and (4) a brush-like structure connected directly or indirectly to the insulator between applied receiver conductors Body, including,
Organ resection tool.
（１）前記印加受手導体間絶縁体を２以上有し、
（２）前記２つのマイクロ波印加用導体間の４つの端で形成される領域の両導体間絶縁体、及び
（３）該両導体間絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
The organ resection tool according to claim 6 comprising the following configuration:
(1) having two or more insulators between the application receiver conductors,
(2) a two-conductor insulator in a region formed by four ends between the two microwave application conductors; and (3) a brush-like shape directly or indirectly connected to the two-conductor insulator. Including,
Organ resection tool.
（１）前記印加受手導体間絶縁体を２以上有し、
（２）前記２つのマイクロ波印加用導体間の４つの端で形成される領域の両導体間絶縁体、及び
（３）該印加受手導体間絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
The organ resection tool according to claim 6 comprising the following configuration:
(1) having two or more insulators between the application receiver conductors,
(2) An insulator between both conductors in a region formed by four ends between the two microwave application conductors, and (3) Directly or indirectly connected to the insulator between the application receiver conductors. A brush-like structure,
Organ resection tool.
（１）前記印加受手導体間絶縁体を２以上有し、
（２）前記両導体間絶縁体、及び
（３）該印加受手導体間絶縁体及び両導体間絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
The organ resection tool according to any one of claims 6 to 8, comprising the following configuration:
(1) having two or more insulators between the application receiver conductors,
(2) the insulator between the two conductors, and (3) the brush-like structure directly or indirectly connected to the insulator between the applied receiver conductor and the insulator between the two conductors,
Organ resection tool.
（１）前記印加受手導体間絶縁体を２以上有し、
（２）前記２つのマイクロ波印加用導体間の４つの端で形成される領域の両導体間絶縁体、
（３）前記マイクロ波受手用導体が前記マイクロ波印加用導体とは反対側に形成される領域である外側絶縁体、及び
（４）該印加受手導体間絶縁体、両導体間絶縁体及び外側絶縁体に直接又は間接的に接続している刷毛状構造体、を含む、
臓器切離操作具。
The organ resection tool according to claim 6 comprising the following configuration:
(1) having two or more insulators between the application receiver conductors,
(2) an inter-conductor insulator in a region formed by four ends between the two microwave application conductors;
(3) an outer insulator in which the microwave receiver conductor is a region formed on the side opposite to the microwave application conductor; and (4) an insulator between the application receiver conductor and an insulator between both conductors. And a brush-like structure connected directly or indirectly to the outer insulator,
Organ resection tool.
前記１又は複数の刷毛状構造体が、その先端近傍まで絶縁材料で被覆されていることを特徴とする臓器切離操作具。
The organ resection tool according to any one of claims 1 to 10,
An organ resection tool, wherein the one or more brush-like structures are covered with an insulating material up to the vicinity of the tip thereof.
前記外部導体又はマイクロ波受手用導体に直接又は間接的に接続した複数の刷毛状構造体が、一列の直線状に配置されていることを特徴とする臓器切離操作具。
The organ resection tool according to claim 1 or 11,
An organ resection tool comprising a plurality of brush-like structures directly or indirectly connected to the external conductor or the microwave receiver conductor arranged in a straight line.
前記中心導体又はマイクロ波印加用導体に直接又は間接的に接続した複数の刷毛状構造体が、一列の直線状に配置されていることを特徴とする臓器切離操作具。
The organ resection tool according to any one of claims 1, 11 to 12,
An organ resection tool characterized in that a plurality of brush-like structures directly or indirectly connected to the central conductor or the microwave application conductor are arranged in a straight line.
前記外部導体又はマイクロ波受手用導体に直接又は間接的に接続した複数の刷毛状構造体並びに前記中心導体又はマイクロ波印加用導体に直接又は間接的に接続した複数の刷毛状構造体が、直線状の一列に配置されていることを特徴とする臓器切離操作具。
The organ resection tool according to any one of claims 1, 11 to 13,
A plurality of brush-like structures directly or indirectly connected to the outer conductor or the microwave receiver conductor and a plurality of brush-like structures directly or indirectly connected to the center conductor or the microwave application conductor, An organ resection tool characterized by being arranged in a straight line.
前記外部導体又はマイクロ波受手用導体に直接又は間接的に接続した複数の刷毛状構造体が直線状の一列に配置されており、並びに、前記中心導体又はマイクロ波印加用導体に直接又は間接的に接続した複数の刷毛状構造体が直線状の一列に配置されており、さらにそれらの２列が略平行であることを特徴とする臓器切離操作具。
The organ resection tool according to any one of claims 1, 11 to 13,
A plurality of brush-like structures directly or indirectly connected to the outer conductor or the microwave receiver conductor are arranged in a straight line, and directly or indirectly to the center conductor or the microwave application conductor. An organ resection tool characterized in that a plurality of connected brush-like structures are arranged in a straight line, and the two lines are substantially parallel.
前記刷毛状構造体の先端がフッ素系コーティング処理、シリコン系コーディング処理、又はダイヤモンド研磨処理されていることを特徴とする臓器切離操作具。
The organ resection tool according to any one of claims 1 to 15,
An organ resection tool, wherein a tip of the brush-like structure is subjected to a fluorine-based coating process, a silicon-based coding process, or a diamond polishing process.
前記刷毛状構造体の先端が右左交互又は一方向に回転動作することを特徴とする臓器切離操作具。
The organ resection tool according to any one of claims 1 to 16,
An organ resection tool characterized in that the tip of the brush-like structure rotates right and left alternately or in one direction.
さらに、振動機能手段を有し、
前記刷毛状構造体の先端が振動させることを特徴とする臓器切離操作具。
The organ resection tool according to any one of claims 1 to 17,
Furthermore, it has vibration function means,
An organ resection tool characterized in that the tip of the brush-like structure is vibrated.
さらに、吸引機能手段を有することを特徴とする臓器切離操作具。 The organ resection tool according to any one of claims 1 to 18, further comprising suction function means.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014213250A JP2016077646A (en) | 2014-10-17 | 2014-10-17 | Organ separation operation tool |
| CN201580056420.4A CN107072715B (en) | 2014-10-17 | 2015-10-16 | Organ removal tool |
| US15/518,370 US20170245931A1 (en) | 2014-10-17 | 2015-10-16 | Organ resection tool |
| PCT/JP2015/005242 WO2016059807A1 (en) | 2014-10-17 | 2015-10-16 | Organ resection tool |
| EP15787701.0A EP3206615B1 (en) | 2014-10-17 | 2015-10-16 | Organ resection tool |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014213250A JP2016077646A (en) | 2014-10-17 | 2014-10-17 | Organ separation operation tool |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2016077646A true JP2016077646A (en) | 2016-05-16 |
Family
ID=54364630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014213250A Pending JP2016077646A (en) | 2014-10-17 | 2014-10-17 | Organ separation operation tool |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20170245931A1 (en) |
| EP (1) | EP3206615B1 (en) |
| JP (1) | JP2016077646A (en) |
| CN (1) | CN107072715B (en) |
| WO (1) | WO2016059807A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021513881A (en) * | 2018-02-15 | 2021-06-03 | ニューウェーブ メディカル, インコーポレイテッドNeuwave Medical, Inc. | Energy delivery device |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01320070A (en) * | 1988-06-21 | 1989-12-26 | Olympus Optical Co Ltd | Probe for thermotherapy |
| JPH02277469A (en) * | 1989-04-19 | 1990-11-14 | Olympus Optical Co Ltd | Probe for microwave treatment |
| JP2005312807A (en) * | 2004-04-30 | 2005-11-10 | Olympus Corp | Energy therapy device |
| JP2010532702A (en) * | 2007-07-06 | 2010-10-14 | バークス・メディカル・インコーポレイテッド | Ablation in the gastrointestinal tract to achieve hemostasis and eradicate disorders with a tendency to bleed |
| JP2010540029A (en) * | 2007-09-20 | 2010-12-24 | メドウェイブス，インコーポレーテッド | Radio wave energy transmission device for biological tissue ablation |
| JP2011135988A (en) * | 2009-12-28 | 2011-07-14 | Shiga Univ Of Medical Science | Medical treatment instrument |
| WO2013172361A1 (en) * | 2012-05-14 | 2013-11-21 | 国立大学法人 滋賀医科大学 | Organ resection tool |
| JP2014511190A (en) * | 2011-01-11 | 2014-05-15 | クレオ・メディカル・リミテッド | Electrosurgical instrument with dual radio frequency and microwave electromagnetic energy |
| WO2015072529A1 (en) * | 2013-11-13 | 2015-05-21 | 国立大学法人 滋賀医科大学 | Microwave-irradiating instrument |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10179594A (en) * | 1996-12-25 | 1998-07-07 | Asahi Optical Co Ltd | Exfoliation tool for operation under observation with endoscope |
| JP2001061847A (en) * | 1999-08-27 | 2001-03-13 | Olympus Optical Co Ltd | Treatment apparatus for organism tissue |
| US20080058803A1 (en) | 2006-08-30 | 2008-03-06 | Kenichi Kimura | Surgical instrument and surgical instrument driving method |
| GB0620060D0 (en) * | 2006-10-10 | 2006-11-22 | Medical Device Innovations Ltd | Surgical antenna |
| JP2010527704A (en) | 2007-05-22 | 2010-08-19 | デイビッド エー． シェクター | Apparatus for tissue attachment / strengthening, apparatus for tissue strengthening, method for attaching and strengthening tissue, and method for strengthening tissue |
| EP2441479B1 (en) | 2009-06-10 | 2018-05-02 | Tohru Tani | Surgical suction nozzle |
| JP5664996B2 (en) | 2010-03-29 | 2015-02-04 | 国立大学法人秋田大学 | Ultrasonic irradiation device |
| WO2013101923A1 (en) * | 2011-12-29 | 2013-07-04 | St. Jude Medical, Atrial Fibrillation Division, Inc. | System for optimized coupling of ablation catheters to body tissues and evaluation of lesions formed by the catheters |
-
2014
- 2014-10-17 JP JP2014213250A patent/JP2016077646A/en active Pending
-
2015
- 2015-10-16 EP EP15787701.0A patent/EP3206615B1/en not_active Not-in-force
- 2015-10-16 CN CN201580056420.4A patent/CN107072715B/en not_active Expired - Fee Related
- 2015-10-16 WO PCT/JP2015/005242 patent/WO2016059807A1/en active Application Filing
- 2015-10-16 US US15/518,370 patent/US20170245931A1/en not_active Abandoned
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01320070A (en) * | 1988-06-21 | 1989-12-26 | Olympus Optical Co Ltd | Probe for thermotherapy |
| JPH02277469A (en) * | 1989-04-19 | 1990-11-14 | Olympus Optical Co Ltd | Probe for microwave treatment |
| JP2005312807A (en) * | 2004-04-30 | 2005-11-10 | Olympus Corp | Energy therapy device |
| JP2010532702A (en) * | 2007-07-06 | 2010-10-14 | バークス・メディカル・インコーポレイテッド | Ablation in the gastrointestinal tract to achieve hemostasis and eradicate disorders with a tendency to bleed |
| JP2010540029A (en) * | 2007-09-20 | 2010-12-24 | メドウェイブス，インコーポレーテッド | Radio wave energy transmission device for biological tissue ablation |
| JP2011135988A (en) * | 2009-12-28 | 2011-07-14 | Shiga Univ Of Medical Science | Medical treatment instrument |
| JP2014511190A (en) * | 2011-01-11 | 2014-05-15 | クレオ・メディカル・リミテッド | Electrosurgical instrument with dual radio frequency and microwave electromagnetic energy |
| WO2013172361A1 (en) * | 2012-05-14 | 2013-11-21 | 国立大学法人 滋賀医科大学 | Organ resection tool |
| WO2015072529A1 (en) * | 2013-11-13 | 2015-05-21 | 国立大学法人 滋賀医科大学 | Microwave-irradiating instrument |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021513881A (en) * | 2018-02-15 | 2021-06-03 | ニューウェーブ メディカル, インコーポレイテッドNeuwave Medical, Inc. | Energy delivery device |
Also Published As
| Publication number | Publication date |
|---|---|
| US20170245931A1 (en) | 2017-08-31 |
| CN107072715B (en) | 2019-10-25 |
| WO2016059807A1 (en) | 2016-04-21 |
| EP3206615A1 (en) | 2017-08-23 |
| CN107072715A (en) | 2017-08-18 |
| EP3206615B1 (en) | 2019-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4429020B2 (en) | Ultrasonic medical treatment device for electrocautery | |
| JP4472759B2 (en) | Ultrasonic treatment device | |
| US5176677A (en) | Endoscopic ultrasonic rotary electro-cauterizing aspirator | |
| US20180070974A1 (en) | Ultrasonic surgical instrument with features for forming bubbles to enhance cavitation | |
| JP5253673B2 (en) | Surgical device | |
| JP6132993B2 (en) | Treatment tool, treatment system | |
| JPWO2012121213A1 (en) | Bipolar treatment device | |
| JPS62211056A (en) | Tissue incision apparatus | |
| JP2006334094A (en) | Surgical instrument | |
| JP2019141691A (en) | Microwave surgical instrument | |
| JP6108501B2 (en) | Microwave irradiation equipment | |
| EP3146923A1 (en) | Treatment tool | |
| JP2018008113A (en) | Organ separating operation tool | |
| JP6660638B2 (en) | Cavity-forming ultrasonic surgical suction device with RF electrode | |
| JP2016077646A (en) | Organ separation operation tool | |
| US8109925B2 (en) | Treatment of breast disease with vibrating device | |
| JP6211228B2 (en) | Medical equipment | |
| JP2607600B2 (en) | Surgical surgery device | |
| JP2001087274A (en) | Ultrasonic treating tool | |
| JP2508203Y2 (en) | Medical ultrasonic horn | |
| CA2901197C (en) | Cavitating ultrasonic surgical aspirator with rf electrodes | |
| JP2001087278A (en) | Ultrasonic operation device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20171012 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20180628 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20180824 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20181026 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20190319 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20190514 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190712 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20191121 |