JP2015531298A - 外部知能を備える医薬給送カプセル - Google Patents
外部知能を備える医薬給送カプセル Download PDFInfo
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- A—HUMAN NECESSITIES
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- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
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- A—HUMAN NECESSITIES
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- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
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- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
- G16H20/13—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
- A61B2562/162—Capsule shaped sensor housings, e.g. for swallowing or implantation
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- A—HUMAN NECESSITIES
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- A61B5/073—Intestinal transmitters
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6861—Capsules, e.g. for swallowing or implanting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2200/00—General characteristics or adaptations
- A61J2200/70—Device provided with specific sensor or indicating means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0418—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1258—Pills, tablets, lozenges
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
- B65D83/0409—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills the dispensing means being adapted for delivering one article, or a single dose, upon each actuation
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Abstract
Description
この出願は「Drug Delivery Capsules With External Intelligence」という名称の2012年10月9日に出願された係属中の米国仮特許出願第61/711,627号の優先権を主張し、その全文をここに参照として援用する。
Claims (30)
- 医薬を投与するためのシステムであって、
複数のカプセルと、
カプセルディスペンサと、
カプセルアクティベータとを含み、
各カプセルは、医薬を収容する貯槽と、出口とを含み、前記医薬は、該出口を通じて前記貯槽から放出され、
前記カプセルディスペンサは、前記カプセルを放出可能に収容し、あるスケジュールに従って使用者に前記カプセルを投薬するように構成され、
前記カプセルアクティベータは、前記使用者への投与に先立ち、投薬されるカプセルを活性化する、
システム。 - 前記出口を通じて前記医薬を放出するためのアクチュエータを更に含む、請求項1に記載のシステム。
- 前記カプセルは、電源を更に含む、請求項2に記載のシステム。
- 前記カプセルアクティベータは、前記電源を充電するための充電器を含む、請求項3に記載のシステム。
- 前記カプセルは、前記使用者における状態を感知するためのセンサを更に含む、請求項1に記載のシステム。
- 前記カプセルディスペンサ及び前記カプセルアクティベータは、単一のユニットに統合される、請求項1に記載のシステム。
- 前記カプセルアクティベータは、投薬されるカプセルを受け入れるように位置付けられ且つ前記カプセルを活性化するように構成される活性化ポートを含む、請求項6に記載のシステム。
- 前記カプセルディスペンサは、ある投薬スケジュールに従ってカプセルを投薬するようにプログラムされるコントローラを含む、請求項1に記載のシステム。
- 前記アクチュエータは、バネを含む、請求項2に記載のシステム。
- 前記バネは、トリガ事象まで圧縮状態において維持され、前記トリガ事象の後に拡張位置まで移動して前記医薬を放出する、請求項9に記載のシステム。
- 前記トリガ事象に先立ち前記バネを前記圧縮状態において維持する破壊可能なフィラメントを更に含む、請求項10に記載のシステム。
- 前記トリガ事象は、前記カプセルでの感知される状態及び所定の時間期間の満了のうちの少なくとも1つを含む、請求項10に記載のシステム。
- 前記アクチュエータはトリガ事象まで前記出口の上に配置される移動可能な覆いであり、そのときに、前記覆いは前記放電から取り外される、請求項1に記載のシステム。
- 情報を外部ユニットに送信するために、前記カプセル中に送信器を更に含む、請求項1に記載のシステム。
- 前記送信される情報は、前記カプセルでセンサによって測定される、請求項14に記載のシステム。
- 前記カプセルディスペンサ及びカプセルアクティベータは、単一のユニットに統合される、請求項1に記載のシステム。
- 前記カプセルは、活性化で又は活性化前に前記外部ユニットによって読み取られる識別を有する、請求項1に記載のシステム。
- 前記カプセルディスペンサ及び/又は前記カプセルアクティベータは、外部システム又はデータベースに接続されて、それらの間で情報を移転する、請求項1に記載のシステム。
- 前記アクチュエータを活性化するためのスイッチを更に含む、請求項2に記載のシステム。
- 前記スイッチは、固定的な電極と、該固定的な電極に対して移動可能な可撓な電極とを含む、請求項19に記載のシステム。
- 前記アクチュエータは、トリガ事象の後に、前記出口を通じて前記医薬を放出する、請求項2に記載のシステム。
- 前記トリガ事象は、前記カプセルで感知される状態、前記カプセルの状態の変化、所定の時間期間の満了、及びスイッチの活性化のうちの少なくとも1つである、請求項21に記載のシステム。
- 被験者に医薬を投与する方法であって、
貯蔵ユニット内に複数のカプセルを貯蔵することを含み、前記カプセルの各々は、前記物質を収容する貯槽と、出口とを含み、前記物質は、該出口を通じて前記貯槽から放出され、
前記カプセルを前記貯槽から使用者に1度に1つずつ投薬することを含み、
使用者へのそれらの投与に先立ち前記カプセルを活性化することを含み、
前記使用者への前記カプセルの投与後に前記貯槽から前記医薬を放出することを含む、
方法。 - 前記医薬の放出を開始させることを更に含む、請求項23に記載の方法。
- 前記開始させるステップは、前記カプセルで状態を感知することを含む、請求項24に記載の方法。
- 前記開始させるステップは、所定の時間期間の満了を含む、請求項24に記載の方法。
- 前記所定の時間期間は、前記活性化するステップ及び前記使用者への前記カプセルの投与のうちの1つで開始する、請求項26に記載の方法。
- 前記投薬するステップは、ある投与スケジュールに従った所定の頻度で起こる、請求項23に記載の方法。
- 前記活性化するステップは、前記カプセル上の電源を充電することを含む、請求項23に記載の方法。
- 前記カプセルからの前記医薬の放出を監視することを更に含む、請求項23に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261711627P | 2012-10-09 | 2012-10-09 | |
US61/711,627 | 2012-10-09 | ||
PCT/US2013/061202 WO2014058605A1 (en) | 2012-10-09 | 2013-09-23 | Drug delivery capsules with external intelligence |
Publications (2)
Publication Number | Publication Date |
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JP2015531298A true JP2015531298A (ja) | 2015-11-02 |
JP6283677B2 JP6283677B2 (ja) | 2018-02-21 |
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JP2015536790A Expired - Fee Related JP6283677B2 (ja) | 2012-10-09 | 2013-09-23 | 外部知能を備える医薬給送カプセル |
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Country | Link |
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US (2) | US9918904B2 (ja) |
EP (1) | EP2906175B1 (ja) |
JP (1) | JP6283677B2 (ja) |
CN (1) | CN105050566B (ja) |
WO (1) | WO2014058605A1 (ja) |
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- 2013-09-23 JP JP2015536790A patent/JP6283677B2/ja not_active Expired - Fee Related
- 2013-09-23 US US14/434,548 patent/US9918904B2/en active Active
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JP7499790B2 (ja) | 2019-05-29 | 2024-06-14 | インキューブ ラブズ, エルエルシー | 療法的製剤を投与するためのデバイスおよび方法 |
JPWO2021090600A1 (ja) * | 2019-11-07 | 2021-05-14 | ||
WO2021090600A1 (ja) * | 2019-11-07 | 2021-05-14 | 株式会社村田製作所 | 服用検知システムおよび服薬デバイス |
JP7070806B2 (ja) | 2019-11-07 | 2022-05-18 | 株式会社村田製作所 | 服用検知システムおよび服薬デバイス |
Also Published As
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EP2906175A4 (en) | 2016-06-22 |
US9918904B2 (en) | 2018-03-20 |
CN105050566A (zh) | 2015-11-11 |
CN105050566B (zh) | 2020-09-22 |
WO2014058605A1 (en) | 2014-04-17 |
EP2906175A1 (en) | 2015-08-19 |
EP2906175B1 (en) | 2018-11-07 |
US20150272830A1 (en) | 2015-10-01 |
JP6283677B2 (ja) | 2018-02-21 |
US20180271752A1 (en) | 2018-09-27 |
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