JP2014529605A5 - 血管形成関連性疾患を治療するためのｎｃ−１を含むタンパク質 - Google Patents
血管形成関連性疾患を治療するためのｎｃ−１を含むタンパク質 Download PDFInfo
- Publication number
- JP2014529605A5 JP2014529605A5 JP2014526504A JP2014526504A JP2014529605A5 JP 2014529605 A5 JP2014529605 A5 JP 2014529605A5 JP 2014526504 A JP2014526504 A JP 2014526504A JP 2014526504 A JP2014526504 A JP 2014526504A JP 2014529605 A5 JP2014529605 A5 JP 2014529605A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- related diseases
- treating angiogenesis
- angiogenesis
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000033115 angiogenesis Effects 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161526535P | 2011-08-23 | 2011-08-23 | |
| US61/526,535 | 2011-08-23 | ||
| EP11178509.3 | 2011-08-23 | ||
| EP11178509A EP2561888A1 (en) | 2011-08-23 | 2011-08-23 | Protein comprising NC-1 for treating angiogenesis-related diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014529605A JP2014529605A (ja) | 2014-11-13 |
| JP2014529605A5 true JP2014529605A5 (ja) | 2015-02-26 |
Family
ID=44534002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014526504A Pending JP2014529605A (ja) | 2011-08-23 | 2012-08-23 | 血管形成関連性疾患を治療する手段及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20140302026A1 (ja) |
| EP (3) | EP2561888A1 (ja) |
| JP (1) | JP2014529605A (ja) |
| CN (1) | CN104271151B (ja) |
| AU (1) | AU2012298430A1 (ja) |
| ES (1) | ES2945008T3 (ja) |
| WO (1) | WO2013026913A2 (ja) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104789585B (zh) * | 2015-04-15 | 2018-03-30 | 南通大学 | 一种在大肠杆菌中生产抗血管剂rt‑x的方法及其应用 |
| AU2016326718B2 (en) | 2015-09-23 | 2022-12-15 | Minerva Biotechnologies Corporation | Method of screening for agents for differentiating stem cells |
| CN109069591B (zh) * | 2015-12-03 | 2023-06-20 | 海德堡生物技术有限公司 | 治疗和诊断纤维化或纤维化相关疾病的手段和方法 |
| WO2017172853A1 (en) | 2016-03-30 | 2017-10-05 | Ab Biosciences, Inc. | Recombinant intravenous immunoglobulin (rivig) compositions and methods for their production and use |
| CN112236448A (zh) * | 2018-04-17 | 2021-01-15 | 海德堡生物技术有限公司 | 用包含NC-1-Fc的蛋白寡聚体治疗血管发生、纤维化和癌症相关疾病的手段和方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5124062B2 (ja) * | 1997-01-21 | 2013-01-23 | ザ・テキサス・エイ・アンド・エム・ユニバーシテイ・システム | フィブロネクチン結合タンパク質組成物および使用法 |
| DE69931908T2 (de) * | 1998-04-15 | 2007-01-11 | Lexigen Pharmaceuticals Corp., Lexington | Steigerung der antikörper-zytokin-fusionsproteinmediierten immunantwort durch mitverabreichung mit einem angiogeneseinhibitor |
| EP1071469A2 (en) * | 1998-04-17 | 2001-01-31 | Lexigen Pharmaceuticals Corp. | Enhancement of antibody-cytokine fusion protein mediated immune responses by co-administration with prostaglandin inhibitor |
| WO1999062944A2 (en) * | 1998-06-03 | 1999-12-09 | The Children's Medical Center Corporation | Protein oligomer compositions comprising endostatin protein and methods of using the same |
| CN100422332C (zh) * | 1998-08-25 | 2008-10-01 | 默克专利股份公司 | 表达以及分泌制管张素和endostatin的免疫融合物 |
| US6825167B1 (en) * | 2000-04-03 | 2004-11-30 | Regents Of The University Of Minnesota | Genetic modification of endostatin |
| US20040009920A1 (en) * | 2000-12-04 | 2004-01-15 | Erkki Ruoslahti | Methods and compositions for inhibiting tumor growth and angiogenesis |
| EP1501868A1 (en) * | 2002-05-08 | 2005-02-02 | Apoxis S.A. | Hexamers of receptors, members of the tnf receptor family, their use in therapy and pharmaceutical compositions comprising the same |
| US7524811B2 (en) * | 2003-08-29 | 2009-04-28 | Children's Medical Center Corporation | Anti-angiogenic peptides from the N-terminus of endostatin |
| ES2325344B1 (es) * | 2004-11-02 | 2010-06-09 | Univ Madrid Autonoma | Inhibidores de angiogenesis multifuncionales y multivalentes. |
| US7662945B2 (en) * | 2005-02-01 | 2010-02-16 | Massachusetts Eye & Ear Infirmary | Neostatins |
| US7625564B2 (en) * | 2006-01-27 | 2009-12-01 | Novagen Holding Corporation | Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo |
| US20080269135A1 (en) * | 2007-04-16 | 2008-10-30 | Retsky Michael W | Method of treatment for early stage cancer |
| CN101143894A (zh) * | 2007-06-22 | 2008-03-19 | 中国药科大学 | 高效抑制血管生成多肽及其物理化学修饰方法和应用 |
| US20110038865A1 (en) * | 2007-06-26 | 2011-02-17 | University Of Miami | Antibody- endostatin fusion protein and its variants |
| TWI476001B (zh) * | 2011-12-26 | 2015-03-11 | Ind Tech Res Inst | 三倍體Ｆｃ融合蛋白及其用途 |
-
2011
- 2011-08-23 EP EP11178509A patent/EP2561888A1/en not_active Withdrawn
-
2012
- 2012-08-23 EP EP12753465.9A patent/EP2747775B1/en active Active
- 2012-08-23 US US14/240,273 patent/US20140302026A1/en not_active Abandoned
- 2012-08-23 CN CN201280051876.8A patent/CN104271151B/zh active Active
- 2012-08-23 AU AU2012298430A patent/AU2012298430A1/en not_active Abandoned
- 2012-08-23 ES ES12753465T patent/ES2945008T3/es active Active
- 2012-08-23 JP JP2014526504A patent/JP2014529605A/ja active Pending
- 2012-08-23 EP EP22206486.7A patent/EP4215206A1/en active Pending
- 2012-08-23 WO PCT/EP2012/066467 patent/WO2013026913A2/en active Application Filing
-
2022
- 2022-10-14 US US17/965,967 patent/US20230341406A1/en active Pending
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