JP2014521503A - 磁気分離装置及び方法 - Google Patents
磁気分離装置及び方法 Download PDFInfo
- Publication number
- JP2014521503A JP2014521503A JP2014523936A JP2014523936A JP2014521503A JP 2014521503 A JP2014521503 A JP 2014521503A JP 2014523936 A JP2014523936 A JP 2014523936A JP 2014523936 A JP2014523936 A JP 2014523936A JP 2014521503 A JP2014521503 A JP 2014521503A
- Authority
- JP
- Japan
- Prior art keywords
- container
- magnetic
- openings
- carriage
- magnetic material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000007885 magnetic separation Methods 0.000 title claims abstract description 47
- 238000000034 method Methods 0.000 title abstract description 28
- 239000006148 magnetic separator Substances 0.000 claims 2
- 239000000696 magnetic material Substances 0.000 abstract description 93
- 239000000463 material Substances 0.000 description 30
- 230000036544 posture Effects 0.000 description 29
- 238000000926 separation method Methods 0.000 description 25
- 210000002105 tongue Anatomy 0.000 description 18
- 230000002093 peripheral effect Effects 0.000 description 9
- 239000003463 adsorbent Substances 0.000 description 8
- 239000007788 liquid Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 238000010079 rubber tapping Methods 0.000 description 2
- 239000004593 Epoxy Substances 0.000 description 1
- 238000011091 antibody purification Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000001742 protein purification Methods 0.000 description 1
- 229910052761 rare earth metal Inorganic materials 0.000 description 1
- 150000002910 rare earth metals Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/284—Magnetic plugs and dipsticks with associated cleaning means, e.g. retractable non-magnetic sleeve
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/005—Pretreatment specially adapted for magnetic separation
- B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
Landscapes
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
- Table Equipment (AREA)
Abstract
Description
103 キャリッジ
105 第1表面
107 第2表面
109 ベース
111 支持構造
113 第1面
115 第2面
117 側方支持部材
119 中心支持部材
121 磁石開口部
123 磁性素子
125a 第1分離軸
125b 別の分離軸
201 主支持部
203 補助支持部
205,503,1005 開口部
207a 第1軸
207b 第2軸
301 舌部
303 溝
305 ベース開口部
307 中心軸
401 脚部
403 脚開口部
501,1001 容器
505,1003 ネジ切り部分
507 エンドキャップ
509 方向
601 非磁性体
603 磁性材料
605 内部領域
801 受容容器
901 吸着材
Claims (5)
- 磁気分離装置において:
磁界を生成するように構成される少なくとも1つの磁性素子と、
容器のネジ切り部分を螺合収容することにより、前記容器を第1支持部に、前記磁性素子に対して姿勢が一定の状態で強固に取り付けるように構成されるネジ切り開口部であって、前記磁気分離装置を逆さまにしたときに前記容器を姿勢が一定の状態に保持するように構成されるネジ切り開口部を含む第1支持部と、
を備える磁気分離装置。 - 前記ネジ切り開口部は、前記第1支持部全体を貫通して延び、前記ネジ切り開口部は、前記容器を、姿勢が一定の状態で強固に吊り下げるように構成される、請求項1に記載の磁気分離装置。
- 前記第1支持部はベースを備え、そして前記磁性素子は前記ベースに支持される、請求項1又は2に記載の磁気分離装置。
- 更に、ベースを備え、そして前記磁性素子は前記ベースに支持される、請求項1乃至3のいずれか一項に記載の磁気分離装置。
- 更に、前記第1支持部を含むキャリッジを備え、そして前記キャリッジは、前記ベースに対して取り付けられて、前記容器が、姿勢が一定の状態になるように構成される、請求項4に記載の磁気分離装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161513265P | 2011-07-29 | 2011-07-29 | |
US61/513,265 | 2011-07-29 | ||
PCT/US2012/044534 WO2013019346A1 (en) | 2011-07-29 | 2012-06-28 | Magnetic separation device and methods |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2014521503A true JP2014521503A (ja) | 2014-08-28 |
JP6072033B2 JP6072033B2 (ja) | 2017-02-01 |
Family
ID=46584330
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014523936A Active JP6072033B2 (ja) | 2011-07-29 | 2012-06-28 | 磁気分離装置及び方法 |
Country Status (4)
Country | Link |
---|---|
US (1) | US9242250B2 (ja) |
EP (1) | EP2736644B1 (ja) |
JP (1) | JP6072033B2 (ja) |
WO (1) | WO2013019346A1 (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6072033B2 (ja) * | 2011-07-29 | 2017-02-01 | コーニング インコーポレイテッド | 磁気分離装置及び方法 |
KR102371946B1 (ko) * | 2013-12-09 | 2022-03-08 | ㈜바이오니아 | 자성입자 분리장치 및 이를 이용한 핵산 또는 단백질의 분리 및 정제방법 |
US11161119B2 (en) * | 2016-05-27 | 2021-11-02 | Dh Technologies Development Pte. Ltd. | Single vial manual magnetic stand and/or holder |
GB2562537B (en) * | 2017-05-19 | 2020-05-06 | Romar International Ltd | Particle removal apparatus |
Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58501367A (ja) * | 1981-08-31 | 1983-08-18 | ベツクマン インスツルメンツ インコ−ポレ−テツド | 試薬の貯蔵、分配装置 |
US4438068A (en) * | 1979-11-13 | 1984-03-20 | Technicon Instruments Corporation | Test-tube assembly for immunoassays utilizing magnetically attractable particles |
JPS6067858A (ja) * | 1983-09-09 | 1985-04-18 | コ−ニング グラス ワ−クス | 固相免疫検定用磁気分離器 |
US4643313A (en) * | 1985-11-26 | 1987-02-17 | Robson Charles H | Apparatus for the controlled dispensing of tablets from multiple containers |
WO1990014891A1 (en) * | 1989-05-31 | 1990-12-13 | Dynal As | Separator device for magnetic particles |
JPH02307552A (ja) * | 1989-05-20 | 1990-12-20 | Kurabo Ind Ltd | デカンテーション装置 |
JPH04325067A (ja) * | 1991-04-24 | 1992-11-13 | Snow Brand Milk Prod Co Ltd | 脂溶性ビタミン類の定量用試料の鹸化容器及びこれを用いる脂溶性ビタミン類の定量用試料の迅速鹸化抽出方法 |
JP2000088840A (ja) * | 1998-09-14 | 2000-03-31 | Kohei Urano | Codの簡易測定方法および該測定方法に使用する分光光度計 |
US6193892B1 (en) * | 1999-03-03 | 2001-02-27 | Promega Corporation | Magnetic separation assembly and method |
JP2003144968A (ja) * | 2001-11-16 | 2003-05-20 | Jsr Corp | 磁気スタンド |
JP2008155107A (ja) * | 2006-12-22 | 2008-07-10 | Tdk Corp | 粒子回収方法及び粒子回収装置 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
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DE3102029A1 (de) * | 1981-01-22 | 1982-08-26 | Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg | Vorrichtung zum abtrennen ferromagnetischer partikel |
DE59410037D1 (de) | 1993-09-17 | 2002-03-14 | Hoffmann La Roche | Analysengerät mit einer Vorrichtung zum Abtrennen magnetischer Mikropartikel |
DE59410373D1 (de) | 1993-09-17 | 2004-06-09 | Hoffmann La Roche | Analysengerät mit einer Vorrichtung zur Suspension von Partikeln und ein Verfahren zur Durchführung der Suspension |
FI944938A0 (fi) | 1994-10-20 | 1994-10-20 | Labsystems Oy | Foerflyttningsanordning |
FI944937A0 (fi) | 1994-10-20 | 1994-10-20 | Labsystems Oy | Separeringsanordning |
FI944939A0 (fi) | 1994-10-20 | 1994-10-20 | Labsystems Oy | Foerfarande foer separering av partiklar |
WO1999024160A1 (de) * | 1997-11-08 | 1999-05-20 | Chemspeed, Ltd. | Vorrichtung zur halterung von temperier- und schüttelbaren reaktionsgefässen |
US6294342B1 (en) | 1999-09-29 | 2001-09-25 | Abbott Laboratories | Magnetically assisted binding assays utilizing a magnetically responsive reagent |
FR2826592B1 (fr) | 2001-06-27 | 2003-08-15 | Bio Merieux | Procede, dispositif, et equipement de separation par voie humide de micro particules magnetiques |
US7785535B2 (en) | 2004-06-07 | 2010-08-31 | Iquum, Inc. | Sample multiprocessing |
US8355132B2 (en) * | 2007-04-06 | 2013-01-15 | Qiagen Gaithersburg, Inc. | Sample adequacy measurement system having a plurality of sample tubes and using turbidity light scattering techniques |
DE102009027454A1 (de) | 2009-07-03 | 2011-01-05 | Robert Bosch Gmbh | Aufnahmebehälter für pharmazeutische Behältnisse |
JP6072033B2 (ja) * | 2011-07-29 | 2017-02-01 | コーニング インコーポレイテッド | 磁気分離装置及び方法 |
-
2012
- 2012-06-28 JP JP2014523936A patent/JP6072033B2/ja active Active
- 2012-06-28 EP EP12740765.8A patent/EP2736644B1/en active Active
- 2012-06-28 WO PCT/US2012/044534 patent/WO2013019346A1/en active Application Filing
- 2012-07-20 US US13/554,565 patent/US9242250B2/en active Active
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4438068A (en) * | 1979-11-13 | 1984-03-20 | Technicon Instruments Corporation | Test-tube assembly for immunoassays utilizing magnetically attractable particles |
JPS58501367A (ja) * | 1981-08-31 | 1983-08-18 | ベツクマン インスツルメンツ インコ−ポレ−テツド | 試薬の貯蔵、分配装置 |
JPS6067858A (ja) * | 1983-09-09 | 1985-04-18 | コ−ニング グラス ワ−クス | 固相免疫検定用磁気分離器 |
US4643313A (en) * | 1985-11-26 | 1987-02-17 | Robson Charles H | Apparatus for the controlled dispensing of tablets from multiple containers |
JPH02307552A (ja) * | 1989-05-20 | 1990-12-20 | Kurabo Ind Ltd | デカンテーション装置 |
WO1990014891A1 (en) * | 1989-05-31 | 1990-12-13 | Dynal As | Separator device for magnetic particles |
JPH04325067A (ja) * | 1991-04-24 | 1992-11-13 | Snow Brand Milk Prod Co Ltd | 脂溶性ビタミン類の定量用試料の鹸化容器及びこれを用いる脂溶性ビタミン類の定量用試料の迅速鹸化抽出方法 |
JP2000088840A (ja) * | 1998-09-14 | 2000-03-31 | Kohei Urano | Codの簡易測定方法および該測定方法に使用する分光光度計 |
US6193892B1 (en) * | 1999-03-03 | 2001-02-27 | Promega Corporation | Magnetic separation assembly and method |
JP2003144968A (ja) * | 2001-11-16 | 2003-05-20 | Jsr Corp | 磁気スタンド |
JP2008155107A (ja) * | 2006-12-22 | 2008-07-10 | Tdk Corp | 粒子回収方法及び粒子回収装置 |
Also Published As
Publication number | Publication date |
---|---|
US20130026104A1 (en) | 2013-01-31 |
EP2736644A1 (en) | 2014-06-04 |
EP2736644B1 (en) | 2020-12-02 |
WO2013019346A1 (en) | 2013-02-07 |
US9242250B2 (en) | 2016-01-26 |
JP6072033B2 (ja) | 2017-02-01 |
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