JP2010506866A - Bactericidal insecticidal composition - Google Patents
Bactericidal insecticidal composition Download PDFInfo
- Publication number
- JP2010506866A JP2010506866A JP2009532705A JP2009532705A JP2010506866A JP 2010506866 A JP2010506866 A JP 2010506866A JP 2009532705 A JP2009532705 A JP 2009532705A JP 2009532705 A JP2009532705 A JP 2009532705A JP 2010506866 A JP2010506866 A JP 2010506866A
- Authority
- JP
- Japan
- Prior art keywords
- plants
- plant
- composition according
- weight
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 52
- 230000000749 insecticidal effect Effects 0.000 title claims abstract description 22
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 7
- ZOCSXAVNDGMNBV-UHFFFAOYSA-N 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile Chemical compound NC1=C(S(=O)C(F)(F)F)C(C#N)=NN1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl ZOCSXAVNDGMNBV-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000005899 Fipronil Substances 0.000 claims abstract description 13
- 229940013764 fipronil Drugs 0.000 claims abstract description 13
- WLPCAERCXQSYLQ-UHFFFAOYSA-N isotianil Chemical compound ClC1=NSC(C(=O)NC=2C(=CC=CC=2)C#N)=C1Cl WLPCAERCXQSYLQ-UHFFFAOYSA-N 0.000 claims abstract description 11
- 235000007164 Oryza sativa Nutrition 0.000 claims description 34
- 235000009566 rice Nutrition 0.000 claims description 34
- 238000000034 method Methods 0.000 claims description 21
- 241000607479 Yersinia pestis Species 0.000 claims description 16
- 239000002689 soil Substances 0.000 claims description 13
- 238000002156 mixing Methods 0.000 claims description 10
- 230000001737 promoting effect Effects 0.000 claims description 10
- 230000008635 plant growth Effects 0.000 claims description 7
- 239000005906 Imidacloprid Substances 0.000 claims description 3
- 230000009471 action Effects 0.000 claims description 3
- YWTYJOPNNQFBPC-UHFFFAOYSA-N imidacloprid Chemical compound [O-][N+](=O)\N=C1/NCCN1CC1=CC=C(Cl)N=C1 YWTYJOPNNQFBPC-UHFFFAOYSA-N 0.000 claims description 3
- 229940056881 imidacloprid Drugs 0.000 claims description 3
- PGOOBECODWQEAB-UHFFFAOYSA-N (E)-clothianidin Chemical compound [O-][N+](=O)\N=C(/NC)NCC1=CN=C(Cl)S1 PGOOBECODWQEAB-UHFFFAOYSA-N 0.000 claims description 2
- HOKKPVIRMVDYPB-UVTDQMKNSA-N (Z)-thiacloprid Chemical compound C1=NC(Cl)=CC=C1CN1C(=N/C#N)/SCC1 HOKKPVIRMVDYPB-UVTDQMKNSA-N 0.000 claims description 2
- JFLRKDZMHNBDQS-UCQUSYKYSA-N CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C.CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C=C[C@H]3C2CC(=O)O1)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C Chemical compound CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C.CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C=C[C@H]3C2CC(=O)O1)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C JFLRKDZMHNBDQS-UCQUSYKYSA-N 0.000 claims description 2
- 239000005888 Clothianidin Substances 0.000 claims description 2
- 239000005930 Spinosad Substances 0.000 claims description 2
- 239000005940 Thiacloprid Substances 0.000 claims description 2
- 239000005941 Thiamethoxam Substances 0.000 claims description 2
- YKBZOVFACRVRJN-UHFFFAOYSA-N dinotefuran Chemical compound [O-][N+](=O)\N=C(/NC)NCC1CCOC1 YKBZOVFACRVRJN-UHFFFAOYSA-N 0.000 claims description 2
- 238000010899 nucleation Methods 0.000 claims description 2
- 229940014213 spinosad Drugs 0.000 claims description 2
- NWWZPOKUUAIXIW-FLIBITNWSA-N thiamethoxam Chemical compound [O-][N+](=O)\N=C/1N(C)COCN\1CC1=CN=C(Cl)S1 NWWZPOKUUAIXIW-FLIBITNWSA-N 0.000 claims description 2
- 241000209094 Oryza Species 0.000 claims 4
- 241000196324 Embryophyta Species 0.000 description 146
- 108090000623 proteins and genes Proteins 0.000 description 49
- -1 cuffstone Substances 0.000 description 34
- 240000007594 Oryza sativa Species 0.000 description 30
- 102000004169 proteins and genes Human genes 0.000 description 28
- 235000018102 proteins Nutrition 0.000 description 27
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 18
- 241000238631 Hexapoda Species 0.000 description 16
- 150000001875 compounds Chemical class 0.000 description 15
- 102000004190 Enzymes Human genes 0.000 description 14
- 108090000790 Enzymes Proteins 0.000 description 14
- 230000000694 effects Effects 0.000 description 11
- 239000004009 herbicide Substances 0.000 description 11
- 230000009261 transgenic effect Effects 0.000 description 11
- 230000009466 transformation Effects 0.000 description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 9
- 238000009472 formulation Methods 0.000 description 9
- 239000008187 granular material Substances 0.000 description 9
- 230000035882 stress Effects 0.000 description 9
- 241000193388 Bacillus thuringiensis Species 0.000 description 8
- 108700019146 Transgenes Proteins 0.000 description 8
- 229940097012 bacillus thuringiensis Drugs 0.000 description 8
- 239000003795 chemical substances by application Substances 0.000 description 8
- 235000014113 dietary fatty acids Nutrition 0.000 description 8
- 235000013399 edible fruits Nutrition 0.000 description 8
- 239000000194 fatty acid Substances 0.000 description 8
- 229930195729 fatty acid Natural products 0.000 description 8
- 239000000843 powder Substances 0.000 description 8
- 230000002786 root growth Effects 0.000 description 8
- 108010020183 3-phosphoshikimate 1-carboxyvinyltransferase Proteins 0.000 description 7
- 241000233866 Fungi Species 0.000 description 7
- 229920002472 Starch Polymers 0.000 description 7
- 240000008042 Zea mays Species 0.000 description 7
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 7
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 7
- 235000005822 corn Nutrition 0.000 description 7
- 230000012010 growth Effects 0.000 description 7
- 230000006872 improvement Effects 0.000 description 7
- 239000008107 starch Substances 0.000 description 7
- 235000019698 starch Nutrition 0.000 description 7
- 101710151559 Crystal protein Proteins 0.000 description 6
- 239000004480 active ingredient Substances 0.000 description 6
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 230000002068 genetic effect Effects 0.000 description 6
- 238000010353 genetic engineering Methods 0.000 description 6
- 239000003112 inhibitor Substances 0.000 description 6
- 230000035772 mutation Effects 0.000 description 6
- 239000002245 particle Substances 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 238000002054 transplantation Methods 0.000 description 6
- 206010021929 Infertility male Diseases 0.000 description 5
- 208000007466 Male Infertility Diseases 0.000 description 5
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 5
- 239000003085 diluting agent Substances 0.000 description 5
- 235000013312 flour Nutrition 0.000 description 5
- 230000002363 herbicidal effect Effects 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 239000007921 spray Substances 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 239000004094 surface-active agent Substances 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 108010000700 Acetolactate synthase Proteins 0.000 description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 4
- 239000005562 Glyphosate Substances 0.000 description 4
- 239000002671 adjuvant Substances 0.000 description 4
- 125000005037 alkyl phenyl group Chemical group 0.000 description 4
- 150000001413 amino acids Chemical class 0.000 description 4
- 125000000319 biphenyl-4-yl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 description 4
- 238000009395 breeding Methods 0.000 description 4
- 239000012141 concentrate Substances 0.000 description 4
- 230000001276 controlling effect Effects 0.000 description 4
- 230000035558 fertility Effects 0.000 description 4
- 229940097068 glyphosate Drugs 0.000 description 4
- XDDAORKBJWWYJS-UHFFFAOYSA-M glyphosate(1-) Chemical compound OP(O)(=O)CNCC([O-])=O XDDAORKBJWWYJS-UHFFFAOYSA-M 0.000 description 4
- IGMNYECMUMZDDF-UHFFFAOYSA-N homogentisic acid Chemical compound OC(=O)CC1=CC(O)=CC=C1O IGMNYECMUMZDDF-UHFFFAOYSA-N 0.000 description 4
- 239000002917 insecticide Substances 0.000 description 4
- 244000005700 microbiome Species 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- 229920001451 polypropylene glycol Polymers 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 239000003053 toxin Substances 0.000 description 4
- 230000001131 transforming effect Effects 0.000 description 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
- CAAMSDWKXXPUJR-UHFFFAOYSA-N 3,5-dihydro-4H-imidazol-4-one Chemical class O=C1CNC=N1 CAAMSDWKXXPUJR-UHFFFAOYSA-N 0.000 description 3
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 3
- 241000193755 Bacillus cereus Species 0.000 description 3
- 241000219198 Brassica Species 0.000 description 3
- 240000002791 Brassica napus Species 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 3
- 241001498622 Cixius wagneri Species 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 235000010469 Glycine max Nutrition 0.000 description 3
- 244000299507 Gossypium hirsutum Species 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 229940100389 Sulfonylurea Drugs 0.000 description 3
- 235000021307 Triticum Nutrition 0.000 description 3
- 244000098338 Triticum aestivum Species 0.000 description 3
- 230000036579 abiotic stress Effects 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 230000001488 breeding effect Effects 0.000 description 3
- 239000004927 clay Substances 0.000 description 3
- 229910052570 clay Inorganic materials 0.000 description 3
- 230000003111 delayed effect Effects 0.000 description 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 239000004503 fine granule Substances 0.000 description 3
- 238000003306 harvesting Methods 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 229920005989 resin Polymers 0.000 description 3
- 239000011347 resin Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 238000009331 sowing Methods 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 231100000765 toxin Toxicity 0.000 description 3
- 108700012359 toxins Proteins 0.000 description 3
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 3
- 239000004563 wettable powder Substances 0.000 description 3
- RSWGJHLUYNHPMX-UHFFFAOYSA-N 1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,10,10a-octahydrophenanthrene-1-carboxylic acid Chemical class C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 description 2
- IANQTJSKSUMEQM-UHFFFAOYSA-N 1-benzofuran Chemical compound C1=CC=C2OC=CC2=C1 IANQTJSKSUMEQM-UHFFFAOYSA-N 0.000 description 2
- YEJRWHAVMIAJKC-UHFFFAOYSA-N 4-Butyrolactone Chemical compound O=C1CCCO1 YEJRWHAVMIAJKC-UHFFFAOYSA-N 0.000 description 2
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Chemical compound CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 description 2
- 229920000856 Amylose Polymers 0.000 description 2
- 235000010591 Appio Nutrition 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 241000219310 Beta vulgaris subsp. vulgaris Species 0.000 description 2
- 241001450781 Bipolaris oryzae Species 0.000 description 2
- 235000003351 Brassica cretica Nutrition 0.000 description 2
- 235000011293 Brassica napus Nutrition 0.000 description 2
- 235000006008 Brassica napus var napus Nutrition 0.000 description 2
- 235000011299 Brassica oleracea var botrytis Nutrition 0.000 description 2
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 2
- 240000003259 Brassica oleracea var. botrytis Species 0.000 description 2
- 244000178937 Brassica oleracea var. capitata Species 0.000 description 2
- 244000221633 Brassica rapa subsp chinensis Species 0.000 description 2
- 235000010149 Brassica rapa subsp chinensis Nutrition 0.000 description 2
- 235000003343 Brassica rupestris Nutrition 0.000 description 2
- 241000219193 Brassicaceae Species 0.000 description 2
- 235000021538 Chard Nutrition 0.000 description 2
- 244000298479 Cichorium intybus Species 0.000 description 2
- 235000007542 Cichorium intybus Nutrition 0.000 description 2
- 240000008067 Cucumis sativus Species 0.000 description 2
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 2
- 108020004414 DNA Proteins 0.000 description 2
- 241001060517 Dicranolaius bellulus Species 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- 102000016680 Dioxygenases Human genes 0.000 description 2
- 108010028143 Dioxygenases Proteins 0.000 description 2
- 241000219428 Fagaceae Species 0.000 description 2
- 229920001503 Glucan Polymers 0.000 description 2
- 244000068988 Glycine max Species 0.000 description 2
- 235000003222 Helianthus annuus Nutrition 0.000 description 2
- 240000005979 Hordeum vulgare Species 0.000 description 2
- 235000007340 Hordeum vulgare Nutrition 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 241000758791 Juglandaceae Species 0.000 description 2
- 229920001732 Lignosulfonate Polymers 0.000 description 2
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 2
- 241000219071 Malvaceae Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000004368 Modified starch Substances 0.000 description 2
- 229920000881 Modified starch Polymers 0.000 description 2
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 2
- 244000061176 Nicotiana tabacum Species 0.000 description 2
- 102000012338 Poly(ADP-ribose) Polymerases Human genes 0.000 description 2
- 108010061844 Poly(ADP-ribose) Polymerases Proteins 0.000 description 2
- 229920000776 Poly(Adenosine diphosphate-ribose) polymerase Polymers 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- 241000813090 Rhizoctonia solani Species 0.000 description 2
- 235000003434 Sesamum indicum Nutrition 0.000 description 2
- 244000040738 Sesamum orientale Species 0.000 description 2
- 240000003768 Solanum lycopersicum Species 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical class OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 description 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 229910021536 Zeolite Inorganic materials 0.000 description 2
- 125000000217 alkyl group Chemical group 0.000 description 2
- 235000019270 ammonium chloride Nutrition 0.000 description 2
- 239000000440 bentonite Substances 0.000 description 2
- 229910000278 bentonite Inorganic materials 0.000 description 2
- 229940092782 bentonite Drugs 0.000 description 2
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 2
- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 239000004359 castor oil Substances 0.000 description 2
- 235000019438 castor oil Nutrition 0.000 description 2
- 239000002734 clay mineral Substances 0.000 description 2
- 238000010367 cloning Methods 0.000 description 2
- 239000003240 coconut oil Substances 0.000 description 2
- 235000019864 coconut oil Nutrition 0.000 description 2
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 2
- 230000007123 defense Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 description 2
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 2
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical compound C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 235000019387 fatty acid methyl ester Nutrition 0.000 description 2
- 230000000855 fungicidal effect Effects 0.000 description 2
- 235000003869 genetically modified organism Nutrition 0.000 description 2
- 230000035784 germination Effects 0.000 description 2
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 2
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 2
- 239000008202 granule composition Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- HJOVHMDZYOCNQW-UHFFFAOYSA-N isophorone Chemical compound CC1=CC(=O)CC(C)(C)C1 HJOVHMDZYOCNQW-UHFFFAOYSA-N 0.000 description 2
- 150000002576 ketones Chemical class 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 235000019426 modified starch Nutrition 0.000 description 2
- 229910052901 montmorillonite Inorganic materials 0.000 description 2
- 235000010460 mustard Nutrition 0.000 description 2
- 238000002703 mutagenesis Methods 0.000 description 2
- 231100000350 mutagenesis Toxicity 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- 239000012188 paraffin wax Substances 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- 108010082527 phosphinothricin N-acetyltransferase Proteins 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000000377 silicon dioxide Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000003892 spreading Methods 0.000 description 2
- 230000007480 spreading Effects 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 125000005504 styryl group Chemical group 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 150000008054 sulfonate salts Chemical class 0.000 description 2
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- 239000000454 talc Substances 0.000 description 2
- 229910052623 talc Inorganic materials 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 239000010457 zeolite Substances 0.000 description 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- OAYXUHPQHDHDDZ-UHFFFAOYSA-N 2-(2-butoxyethoxy)ethanol Chemical compound CCCCOCCOCCO OAYXUHPQHDHDDZ-UHFFFAOYSA-N 0.000 description 1
- XXXFZKQPYACQLD-UHFFFAOYSA-N 2-(2-hydroxyethoxy)ethyl acetate Chemical compound CC(=O)OCCOCCO XXXFZKQPYACQLD-UHFFFAOYSA-N 0.000 description 1
- PTTPXKJBFFKCEK-UHFFFAOYSA-N 2-Methyl-4-heptanone Chemical compound CC(C)CC(=O)CC(C)C PTTPXKJBFFKCEK-UHFFFAOYSA-N 0.000 description 1
- IAJOBQBIJHVGMQ-UHFFFAOYSA-N 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid Chemical compound CP(O)(=O)CCC(N)C(O)=O IAJOBQBIJHVGMQ-UHFFFAOYSA-N 0.000 description 1
- CFWRDBDJAOHXSH-SECBINFHSA-N 2-azaniumylethyl [(2r)-2,3-diacetyloxypropyl] phosphate Chemical compound CC(=O)OC[C@@H](OC(C)=O)COP(O)(=O)OCCN CFWRDBDJAOHXSH-SECBINFHSA-N 0.000 description 1
- ZNQVEEAIQZEUHB-UHFFFAOYSA-N 2-ethoxyethanol Chemical compound CCOCCO ZNQVEEAIQZEUHB-UHFFFAOYSA-N 0.000 description 1
- HXDLWJWIAHWIKI-UHFFFAOYSA-N 2-hydroxyethyl acetate Chemical compound CC(=O)OCCO HXDLWJWIAHWIKI-UHFFFAOYSA-N 0.000 description 1
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
- KKADPXVIOXHVKN-UHFFFAOYSA-M 3-(4-hydroxyphenyl)pyruvate Chemical compound OC1=CC=C(CC(=O)C([O-])=O)C=C1 KKADPXVIOXHVKN-UHFFFAOYSA-M 0.000 description 1
- PRZRAMLXTKZUHF-UHFFFAOYSA-N 5-oxo-n-sulfonyl-4h-triazole-1-carboxamide Chemical compound O=S(=O)=NC(=O)N1N=NCC1=O PRZRAMLXTKZUHF-UHFFFAOYSA-N 0.000 description 1
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 1
- 244000215068 Acacia senegal Species 0.000 description 1
- 241000238876 Acari Species 0.000 description 1
- 241000589159 Agrobacterium sp. Species 0.000 description 1
- 241000123646 Allioideae Species 0.000 description 1
- 244000291564 Allium cepa Species 0.000 description 1
- 235000002732 Allium cepa var. cepa Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 235000010585 Ammi visnaga Nutrition 0.000 description 1
- 244000153158 Ammi visnaga Species 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 240000002470 Amphicarpaea bracteata Species 0.000 description 1
- 244000144725 Amygdalus communis Species 0.000 description 1
- 229920000945 Amylopectin Polymers 0.000 description 1
- 241000208223 Anacardiaceae Species 0.000 description 1
- 241000208173 Apiaceae Species 0.000 description 1
- 240000007087 Apium graveolens Species 0.000 description 1
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 description 1
- 244000153885 Appio Species 0.000 description 1
- 235000011330 Armoracia rusticana Nutrition 0.000 description 1
- 240000003291 Armoracia rusticana Species 0.000 description 1
- 241001167018 Aroa Species 0.000 description 1
- 241000123643 Asparagaceae Species 0.000 description 1
- 244000003416 Asparagus officinalis Species 0.000 description 1
- 235000005340 Asparagus officinalis Nutrition 0.000 description 1
- 241000208838 Asteraceae Species 0.000 description 1
- 235000000832 Ayote Nutrition 0.000 description 1
- 108010016529 Bacillus amyloliquefaciens ribonuclease Proteins 0.000 description 1
- 235000021537 Beetroot Nutrition 0.000 description 1
- 235000018185 Betula X alpestris Nutrition 0.000 description 1
- 235000018212 Betula X uliginosa Nutrition 0.000 description 1
- 241000219495 Betulaceae Species 0.000 description 1
- 241000255789 Bombyx mori Species 0.000 description 1
- 241000167854 Bourreria succulenta Species 0.000 description 1
- 244000174111 Brassica adpressa Species 0.000 description 1
- 235000005156 Brassica carinata Nutrition 0.000 description 1
- 244000257790 Brassica carinata Species 0.000 description 1
- 244000178993 Brassica juncea Species 0.000 description 1
- 235000014698 Brassica juncea var multisecta Nutrition 0.000 description 1
- 240000000385 Brassica napus var. napus Species 0.000 description 1
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 1
- 235000004221 Brassica oleracea var gemmifera Nutrition 0.000 description 1
- 235000017647 Brassica oleracea var italica Nutrition 0.000 description 1
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 1
- 244000308368 Brassica oleracea var. gemmifera Species 0.000 description 1
- 244000304217 Brassica oleracea var. gongylodes Species 0.000 description 1
- 240000008100 Brassica rapa Species 0.000 description 1
- 235000011292 Brassica rapa Nutrition 0.000 description 1
- 235000006618 Brassica rapa subsp oleifera Nutrition 0.000 description 1
- 235000000536 Brassica rapa subsp pekinensis Nutrition 0.000 description 1
- 235000000540 Brassica rapa subsp rapa Nutrition 0.000 description 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 1
- 229910021532 Calcite Inorganic materials 0.000 description 1
- 240000001548 Camellia japonica Species 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 241001157813 Cercospora Species 0.000 description 1
- 241001660259 Cereus <cactus> Species 0.000 description 1
- 241000871189 Chenopodiaceae Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 240000006740 Cichorium endivia Species 0.000 description 1
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 235000013162 Cocos nucifera Nutrition 0.000 description 1
- 244000060011 Cocos nucifera Species 0.000 description 1
- 108091026890 Coding region Proteins 0.000 description 1
- 241000254173 Coleoptera Species 0.000 description 1
- 241000219112 Cucumis Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 240000004244 Cucurbita moschata Species 0.000 description 1
- 235000009854 Cucurbita moschata Nutrition 0.000 description 1
- 235000009804 Cucurbita pepo subsp pepo Nutrition 0.000 description 1
- 241000219104 Cucurbitaceae Species 0.000 description 1
- 244000301850 Cupressus sempervirens Species 0.000 description 1
- 244000019459 Cynara cardunculus Species 0.000 description 1
- 235000019106 Cynara scolymus Nutrition 0.000 description 1
- 244000000626 Daucus carota Species 0.000 description 1
- 235000002767 Daucus carota Nutrition 0.000 description 1
- 101710088194 Dehydrogenase Proteins 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- UDSFAEKRVUSQDD-UHFFFAOYSA-N Dimethyl adipate Chemical compound COC(=O)CCCCC(=O)OC UDSFAEKRVUSQDD-UHFFFAOYSA-N 0.000 description 1
- MUXOBHXGJLMRAB-UHFFFAOYSA-N Dimethyl succinate Chemical compound COC(=O)CCC(=O)OC MUXOBHXGJLMRAB-UHFFFAOYSA-N 0.000 description 1
- 241000591358 Eballistra oryzae Species 0.000 description 1
- 235000007351 Eleusine Nutrition 0.000 description 1
- 241000209215 Eleusine Species 0.000 description 1
- 101000999829 Escherichia coli (strain K12) NH(3)-dependent NAD(+) synthetase Proteins 0.000 description 1
- FNELVJVBIYMIMC-UHFFFAOYSA-N Ethiprole Chemical compound N1=C(C#N)C(S(=O)CC)=C(N)N1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl FNELVJVBIYMIMC-UHFFFAOYSA-N 0.000 description 1
- 241000220485 Fabaceae Species 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- 240000009088 Fragaria x ananassa Species 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 239000005561 Glufosinate Substances 0.000 description 1
- 208000012766 Growth delay Diseases 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- 241000208818 Helianthus Species 0.000 description 1
- 244000020551 Helianthus annuus Species 0.000 description 1
- 241000258937 Hemiptera Species 0.000 description 1
- 229920001202 Inulin Polymers 0.000 description 1
- 240000007049 Juglans regia Species 0.000 description 1
- 235000009496 Juglans regia Nutrition 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- 241000725028 Kuwayama Species 0.000 description 1
- YEJSPQZHMWGIGP-YFKPBYRVSA-N L-glutamic acid, dimethyl ester Chemical compound COC(=O)CC[C@H](N)C(=O)OC YEJSPQZHMWGIGP-YFKPBYRVSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 235000003228 Lactuca sativa Nutrition 0.000 description 1
- 240000008415 Lactuca sativa Species 0.000 description 1
- 241000218195 Lauraceae Species 0.000 description 1
- 235000007849 Lepidium sativum Nutrition 0.000 description 1
- 244000211187 Lepidium sativum Species 0.000 description 1
- 241000255777 Lepidoptera Species 0.000 description 1
- 235000004431 Linum usitatissimum Nutrition 0.000 description 1
- 240000006240 Linum usitatissimum Species 0.000 description 1
- 241000966204 Lissorhoptrus oryzophilus Species 0.000 description 1
- 244000070406 Malus silvestris Species 0.000 description 1
- 241000218231 Moraceae Species 0.000 description 1
- 240000005561 Musa balbisiana Species 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 241000234615 Musaceae Species 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 description 1
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 description 1
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 1
- 241000244206 Nematoda Species 0.000 description 1
- 241000359016 Nephotettix Species 0.000 description 1
- 108010019703 Nicotinamidase Proteins 0.000 description 1
- 102000015532 Nicotinamide phosphoribosyltransferase Human genes 0.000 description 1
- 108010064862 Nicotinamide phosphoribosyltransferase Proteins 0.000 description 1
- 102000000780 Nicotinate phosphoribosyltransferase Human genes 0.000 description 1
- 108700040046 Nicotinate phosphoribosyltransferases Proteins 0.000 description 1
- 235000007413 Nigella arvensis Nutrition 0.000 description 1
- 244000090896 Nigella sativa Species 0.000 description 1
- 235000016698 Nigella sativa Nutrition 0.000 description 1
- 241001556089 Nilaparvata lugens Species 0.000 description 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
- 239000004534 Oil miscible flowable concentrate Substances 0.000 description 1
- 241000207834 Oleaceae Species 0.000 description 1
- 241001570894 Oulema oryzae Species 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 241001622642 Parnara bada Species 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- 244000062780 Petroselinum sativum Species 0.000 description 1
- 240000007377 Petunia x hybrida Species 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 235000016761 Piper aduncum Nutrition 0.000 description 1
- 240000003889 Piper guineense Species 0.000 description 1
- 235000017804 Piper guineense Nutrition 0.000 description 1
- 235000008184 Piper nigrum Nutrition 0.000 description 1
- 240000004713 Pisum sativum Species 0.000 description 1
- 235000010582 Pisum sativum Nutrition 0.000 description 1
- 241000209504 Poaceae Species 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 235000009827 Prunus armeniaca Nutrition 0.000 description 1
- 244000018633 Prunus armeniaca Species 0.000 description 1
- 240000005809 Prunus persica Species 0.000 description 1
- 235000006040 Prunus persica var persica Nutrition 0.000 description 1
- 241000220324 Pyrus Species 0.000 description 1
- 241001385948 Pythium sp. Species 0.000 description 1
- 235000019484 Rapeseed oil Nutrition 0.000 description 1
- 244000088415 Raphanus sativus Species 0.000 description 1
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 description 1
- 108010083644 Ribonucleases Proteins 0.000 description 1
- 102000006382 Ribonucleases Human genes 0.000 description 1
- 235000019774 Rice Bran oil Nutrition 0.000 description 1
- 235000004789 Rosa xanthina Nutrition 0.000 description 1
- 241000220222 Rosaceae Species 0.000 description 1
- 241001107098 Rubiaceae Species 0.000 description 1
- 241001093501 Rutaceae Species 0.000 description 1
- 241000293869 Salmonella enterica subsp. enterica serovar Typhimurium Species 0.000 description 1
- 241000576755 Sclerotia Species 0.000 description 1
- 241000209056 Secale Species 0.000 description 1
- 235000007238 Secale cereale Nutrition 0.000 description 1
- 241000254152 Sitophilus oryzae Species 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 235000002597 Solanum melongena Nutrition 0.000 description 1
- 244000061458 Solanum melongena Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 244000062793 Sorghum vulgare Species 0.000 description 1
- 235000009337 Spinacia oleracea Nutrition 0.000 description 1
- 244000300264 Spinacia oleracea Species 0.000 description 1
- 241000187747 Streptomyces Species 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 235000021536 Sugar beet Nutrition 0.000 description 1
- 241000011383 Tilletia horrida Species 0.000 description 1
- 235000019714 Triticale Nutrition 0.000 description 1
- 240000006064 Urena lobata Species 0.000 description 1
- 235000010749 Vicia faba Nutrition 0.000 description 1
- 240000006677 Vicia faba Species 0.000 description 1
- 235000002098 Vicia faba var. major Nutrition 0.000 description 1
- 241000726445 Viroids Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 241000589636 Xanthomonas campestris Species 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 241000845449 [Rhizoctonia] oryzae Species 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 108020002494 acetyltransferase Proteins 0.000 description 1
- 102000005421 acetyltransferase Human genes 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000004479 aerosol dispenser Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 229940072056 alginate Drugs 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 150000001335 aliphatic alkanes Chemical class 0.000 description 1
- 229920000180 alkyd Polymers 0.000 description 1
- 150000003973 alkyl amines Chemical class 0.000 description 1
- 150000004996 alkyl benzenes Chemical class 0.000 description 1
- 150000005215 alkyl ethers Chemical class 0.000 description 1
- 125000005211 alkyl trimethyl ammonium group Chemical group 0.000 description 1
- 125000002947 alkylene group Chemical group 0.000 description 1
- 235000020224 almond Nutrition 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 239000002280 amphoteric surfactant Substances 0.000 description 1
- 229940072049 amyl acetate Drugs 0.000 description 1
- PGMYKACGEOXYJE-UHFFFAOYSA-N anhydrous amyl acetate Natural products CCCCCOC(C)=O PGMYKACGEOXYJE-UHFFFAOYSA-N 0.000 description 1
- 150000001449 anionic compounds Chemical class 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 230000000433 anti-nutritional effect Effects 0.000 description 1
- 230000000692 anti-sense effect Effects 0.000 description 1
- 239000002518 antifoaming agent Substances 0.000 description 1
- 235000021016 apples Nutrition 0.000 description 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 description 1
- 235000016520 artichoke thistle Nutrition 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 235000013871 bee wax Nutrition 0.000 description 1
- 239000012166 beeswax Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000012216 bentonite Nutrition 0.000 description 1
- 229960001716 benzalkonium Drugs 0.000 description 1
- UREZNYTWGJKWBI-UHFFFAOYSA-M benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 description 1
- 229960001950 benzethonium chloride Drugs 0.000 description 1
- CYDRXTMLKJDRQH-UHFFFAOYSA-N benzododecinium Chemical compound CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 CYDRXTMLKJDRQH-UHFFFAOYSA-N 0.000 description 1
- 150000001558 benzoic acid derivatives Chemical class 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- 235000021028 berry Nutrition 0.000 description 1
- 229960003237 betaine Drugs 0.000 description 1
- GINJFDRNADDBIN-FXQIFTODSA-N bilanafos Chemical compound OC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCP(C)(O)=O GINJFDRNADDBIN-FXQIFTODSA-N 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 238000010352 biotechnological method Methods 0.000 description 1
- 239000004067 bulking agent Substances 0.000 description 1
- CURLHBZYTFVCRG-UHFFFAOYSA-N butan-2-yl n-(3-chlorophenyl)carbamate Chemical compound CCC(C)OC(=O)NC1=CC=CC(Cl)=C1 CURLHBZYTFVCRG-UHFFFAOYSA-N 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 239000000378 calcium silicate Substances 0.000 description 1
- 229910052918 calcium silicate Inorganic materials 0.000 description 1
- OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000004203 carnauba wax Substances 0.000 description 1
- 235000013869 carnauba wax Nutrition 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 235000019693 cherries Nutrition 0.000 description 1
- 235000003733 chicria Nutrition 0.000 description 1
- 210000003763 chloroplast Anatomy 0.000 description 1
- 229910052956 cinnabar Inorganic materials 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- HPXRVTGHNJAIIH-UHFFFAOYSA-N cyclohexanol Chemical compound OC1CCCCC1 HPXRVTGHNJAIIH-UHFFFAOYSA-N 0.000 description 1
- 210000000805 cytoplasm Anatomy 0.000 description 1
- 230000001086 cytosolic effect Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000023753 dehiscence Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- ONCZQWJXONKSMM-UHFFFAOYSA-N dialuminum;disodium;oxygen(2-);silicon(4+);hydrate Chemical compound O.[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[Na+].[Na+].[Al+3].[Al+3].[Si+4].[Si+4].[Si+4].[Si+4] ONCZQWJXONKSMM-UHFFFAOYSA-N 0.000 description 1
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 description 1
- CZZYITDELCSZES-UHFFFAOYSA-N diphenylmethane Chemical group C=1C=CC=CC=1CC1=CC=CC=C1 CZZYITDELCSZES-UHFFFAOYSA-N 0.000 description 1
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 1
- YEJSPQZHMWGIGP-UHFFFAOYSA-N dl-glutamic acid dimethyl ester Natural products COC(=O)CCC(N)C(=O)OC YEJSPQZHMWGIGP-UHFFFAOYSA-N 0.000 description 1
- 239000010459 dolomite Substances 0.000 description 1
- 229910000514 dolomite Inorganic materials 0.000 description 1
- 230000002222 downregulating effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000004495 emulsifiable concentrate Substances 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 230000003631 expected effect Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000004507 flowable concentrates for seed treatment Substances 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000004513 gas generating product Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 238000012239 gene modification Methods 0.000 description 1
- 230000005017 genetic modification Effects 0.000 description 1
- 235000013617 genetically modified food Nutrition 0.000 description 1
- 235000010985 glycerol esters of wood rosin Nutrition 0.000 description 1
- MNWFXJYAOYHMED-UHFFFAOYSA-M heptanoate Chemical compound CCCCCCC([O-])=O MNWFXJYAOYHMED-UHFFFAOYSA-M 0.000 description 1
- 238000003898 horticulture Methods 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- KIUKXJAPPMFGSW-MNSSHETKSA-N hyaluronan Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-MNSSHETKSA-N 0.000 description 1
- 229940099552 hyaluronan Drugs 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 239000011147 inorganic material Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 description 1
- 229940029339 inulin Drugs 0.000 description 1
- 238000003973 irrigation Methods 0.000 description 1
- 230000002262 irrigation Effects 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 239000003350 kerosene Substances 0.000 description 1
- 238000004898 kneading Methods 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- AIHDCSAXVMAMJH-GFBKWZILSA-N levan Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@@H]1[C@@H](O)[C@H](O)[C@](CO)(CO[C@@H]2[C@H]([C@H](O)[C@@](O)(CO)O2)O)O1 AIHDCSAXVMAMJH-GFBKWZILSA-N 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 239000004515 macrogranule Substances 0.000 description 1
- 210000000260 male genitalia Anatomy 0.000 description 1
- 239000004579 marble Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 235000010981 methylcellulose Nutrition 0.000 description 1
- 108091040857 miR-604 stem-loop Proteins 0.000 description 1
- 235000019713 millet Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 230000002438 mitochondrial effect Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 229950006238 nadide Drugs 0.000 description 1
- PSZYNBSKGUBXEH-UHFFFAOYSA-M naphthalene-1-sulfonate Chemical compound C1=CC=C2C(S(=O)(=O)[O-])=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-M 0.000 description 1
- PSZYNBSKGUBXEH-UHFFFAOYSA-N naphthalene-1-sulfonic acid Chemical class C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-N 0.000 description 1
- 229940042880 natural phospholipid Drugs 0.000 description 1
- 229920005615 natural polymer Polymers 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 1
- JOUIQRNQJGXQDC-ZYUZMQFOSA-L nicotinate D-ribonucleotide(2-) Chemical compound O1[C@H](COP([O-])([O-])=O)[C@@H](O)[C@@H](O)[C@@H]1[N+]1=CC=CC(C([O-])=O)=C1 JOUIQRNQJGXQDC-ZYUZMQFOSA-L 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 239000007764 o/w emulsion Substances 0.000 description 1
- 239000004536 oil dispersible powder Substances 0.000 description 1
- 239000004535 oil miscible liquid Substances 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 230000008723 osmotic stress Effects 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- 235000011197 perejil Nutrition 0.000 description 1
- 239000010451 perlite Substances 0.000 description 1
- 235000019362 perlite Nutrition 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- RCMHUQGSSVZPDG-UHFFFAOYSA-N phenoxybenzene;phosphoric acid Chemical compound OP(O)(O)=O.C=1C=CC=CC=1OC1=CC=CC=C1 RCMHUQGSSVZPDG-UHFFFAOYSA-N 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 230000029553 photosynthesis Effects 0.000 description 1
- 238000010672 photosynthesis Methods 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000003032 phytopathogenic effect Effects 0.000 description 1
- 230000008121 plant development Effects 0.000 description 1
- 230000037039 plant physiology Effects 0.000 description 1
- 239000004541 plant rodlet Substances 0.000 description 1
- 239000002798 polar solvent Substances 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920001515 polyalkylene glycol Polymers 0.000 description 1
- 229920005646 polycarboxylate Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000157 polyfructose Polymers 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 210000001938 protoplast Anatomy 0.000 description 1
- 239000008262 pumice Substances 0.000 description 1
- 235000015136 pumpkin Nutrition 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 239000003161 ribonuclease inhibitor Substances 0.000 description 1
- 239000008165 rice bran oil Substances 0.000 description 1
- 230000005070 ripening Effects 0.000 description 1
- 229940071089 sarcosinate Drugs 0.000 description 1
- 230000007330 shade avoidance Effects 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 229940080314 sodium bentonite Drugs 0.000 description 1
- 229910000280 sodium bentonite Inorganic materials 0.000 description 1
- 239000004550 soluble concentrate Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 235000021012 strawberries Nutrition 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 239000004560 ultra-low volume (ULV) liquid Substances 0.000 description 1
- 239000004555 ultra-low volume (ULV) suspension Substances 0.000 description 1
- 244000045561 useful plants Species 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000010455 vermiculite Substances 0.000 description 1
- 229910052902 vermiculite Inorganic materials 0.000 description 1
- 235000019354 vermiculite Nutrition 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- 235000020234 walnut Nutrition 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 241000228158 x Triticosecale Species 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
- 239000004711 α-olefin Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/50—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids the nitrogen atom being doubly bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N51/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds having the sequences of atoms O—N—S, X—O—S, N—N—S, O—N—N or O-halogen, regardless of the number of bonds each atom has and with no atom of these sequences forming part of a heterocyclic ring
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Pretreatment Of Seeds And Plants (AREA)
Abstract
(a)3,4−ジクロロ−N−(2−シアノフェニル)イソチアゾール−5−カルボキサミドと、(b)フィプロニル又はエチプロールを組み合わせて含んでなる殺菌殺虫組成物。 A bactericidal insecticidal composition comprising a combination of (a) 3,4-dichloro-N- (2-cyanophenyl) isothiazole-5-carboxamide and (b) fipronil or etiprol.
Description
本発明は殺菌殺虫組成物に関する。詳しくは、育苗箱に施用する殺菌殺虫組成物に関し、副次作用として植物生長促進作用を有する該組成物にも関する。 The present invention relates to a bactericidal insecticidal composition. Specifically, it relates to a fungicidal insecticidal composition applied to a seedling box, and also relates to the composition having a plant growth promoting action as a secondary action.
水稲箱育苗において、播種時に、長期残効性殺虫剤および殺菌剤を処理する方法は、本田生育期間中の防除回数を低減できるため、水稲栽培の省力化・低コスト化に有効な手段として普及が進み、既に日本の各地で広く行われている。 In paddy rice box seedlings, the method of treating long-lasting insecticides and fungicides at the time of sowing can be used as an effective means for labor saving and cost reduction of paddy rice cultivation because the number of control during the growing period of Honda can be reduced. Has already been promoted and is already widely practiced in various parts of Japan.
本発明の組成物に含まれるそれぞれの有効成分は、通常の栽培条件下で播種時に単独で処理した場合、イネの生育に影響はないが、湛水育苗(通称プール育苗)や、異常高温、低温、乾燥などの条件によっては、根部の生育が多少遅延する場合がある。 Each active ingredient contained in the composition of the present invention, when treated alone at the time of sowing under normal cultivation conditions, does not affect the growth of rice, but it is a flooded seedling (commonly called pool raising), abnormally high temperature, Depending on conditions such as low temperature and drying, the growth of the root may be somewhat delayed.
殺菌性化合物の3,4−ジクロロ−N−(2−シアノフェニル)イソチアゾール−5−カルボキサミドと公知殺虫剤との混合組成物はすでに知られている(WO2005/009131公報)。 A mixed composition of the bactericidal compound 3,4-dichloro-N- (2-cyanophenyl) isothiazole-5-carboxamide and a known insecticide is already known (WO 2005/009131).
本発明者らは、下記に示す組み合わせが、本田移植後の水稲の病害虫に対し、優れた防除効果を現わすと共に、根の生育を促進して育苗期間を短縮し、通常と異なる条件においても、安定した水稲苗の根部の良好な生育をもたらすことを見出し、本発明を完成した。 The present inventors have shown that the combination shown below has an excellent control effect against pests of rice after transplanting to Honda, and promotes root growth to shorten the seedling raising period, even under different conditions. As a result, the present inventors have found that stable root growth of paddy rice seedlings can be achieved and the present invention has been completed.
かくして、本発明は
(a)3,4−ジクロロ−N−(2−シアノフェニル)イソチアゾール−5−カルボキサミド(以下、イソチアニルと略記する)と、
(b)フィプロニル又はエチプロールとを組み合わせて含んでなる殺菌殺虫組成物を提供するものである。
Thus, the present invention provides (a) 3,4-dichloro-N- (2-cyanophenyl) isothiazole-5-carboxamide (hereinafter abbreviated as isothianyl);
(B) A fungicidal insecticidal composition comprising a combination of fipronil or etiprole is provided.
また、本発明は、育苗箱に水稲種子を播種し、上記組成物を覆土前に施用することからなる、本田移植後の病害虫を防除する方法、並びに、育苗箱の床土、又は水稲種子を覆土する土に同じく上記組成物を混合することからなる、本田移植後の病害虫を防除する方法を提供するものでもある。 The present invention also includes a method for controlling pests after transplanting to Honda, comprising seeding paddy rice seeds in a seedling box and applying the above composition before covering the soil, as well as floor soil of the seedling box or paddy rice seeds. The present invention also provides a method for controlling pests after transplanting to Honda, which comprises mixing the above composition with the soil to be covered.
本発明によれば、上記(a)のイソチアニルと(b)のフィプロニル又はエチプロールを組み合わせてなる組成物に具体的に特定された記載も、該組成物の具体的な生物効果も本願出願日前の刊行物には開示されていない。今までのところ、WO2005/009131において、フィプロニルおよびエチプロールは、混合パートナーの長いリスト中で化合物(A)に対する可能な混合パートナーとしてのみ、一般的な式中で開示されている。さらに、これらの混合物は、非常に優れた殺菌活性があることについて、WO2005/009131にのみ記載されている。 According to the present invention, the description specifically identified in the composition comprising the combination of isotianil of (a) and fipronil or etiprole of (b), the specific biological effect of the composition, It is not disclosed in the publication. So far, in WO2005 / 009131 fipronil and etiprol are disclosed in the general formula only as possible mixing partners for compound (A) in the long list of mixing partners. Furthermore, these mixtures are only described in WO 2005/009131 for their very good bactericidal activity.
驚くべきことに、本発明の(a)のイソチアニルと(b)のフィプロニル又はエチプロールを組み合わせて含んでなる殺菌殺虫組成物は水稲の病害虫に対し、優れた防除効果を現わすと共に、該組成物を施用しない場合に比べて、水稲苗の根の生育を極めて良好に促進するという植物生長促 進作用を示すことができ、その結果、水稲苗の育苗期間の短縮をもたらし、通常と異なる条件下でも安定な根部の生育を達成させることができる。従って、本発明の組成物は、病害虫防除と育苗期間の短縮という生産性の両面で極めて有利で有用なものである。 Surprisingly, the bactericidal insecticidal composition comprising the combination of (i) isotianil of (a) and fipronil or etiprole of (b) of the present invention exhibits an excellent control effect against rice pests and the composition. Compared to the case where no seedling is applied, the plant growth promotion effect of promoting the growth of roots of rice seedlings can be shown very well. However, stable root growth can be achieved. Therefore, the composition of the present invention is extremely advantageous and useful in terms of both productivity of pest control and shortening of the seedling raising period.
本発明は、更に、上記(a)と(b)の二成分の組み合わせに加えて、(c)のイミダクロプリド、チアクロプリド、クロチアニジン、ジノテフラン、チアメトキサム、スピノサド、チフルザミド、フラメトピル、オリサストロビンおよびBYF14182より成る群から選ばれる少なくとも1種を含んでなる組成物も提供するものであり、この(a)、(b)および(c)の各成分を組み合わせてなる組成物も、上記した病害虫防除と生産性の両面で極めて有利且つ有用なものである。 The present invention further includes, in addition to the combination of the two components (a) and (b) above, the group consisting of imidacloprid, thiacloprid, clothianidin, dinotefuran, thiamethoxam, spinosad, tifluzamide, flametopyr, orisatrobin and BYF14182. A composition comprising at least one selected from the above is also provided, and the composition comprising a combination of the components (a), (b) and (c) is also capable of both pest control and productivity. It is extremely advantageous and useful.
本発明における(a)のイソチアニルは、特表2001−522840号公報に示される病害防除剤の一つであり、(b)のフィプロニルおよびエチプロール、また(c)の前記各成分の内、オリサストロビンとBYF14182を除き、Pesticide Manual(2003年13版 BCPC発行)に記載される化合物である。オリサストロビンは独公開特許第19539324号に記載の化合物である。BYF14182はWO2006/092291公報に記載の化合物である。 The isotianil of (a) in the present invention is one of disease control agents disclosed in JP-T-2001-522840, and fipronil and etiprole of (b), and among the above components of (c), Except for BYF14182, these compounds are described in Pesticide Manual (2003 edition, published by BCPC). Orisatrobin is a compound described in German Patent No. 19539324. BYF14182 is a compound described in WO2006 / 092921.
本発明の組み合わせ組成物において、各有効成分の混合比は、限定的に制限されるものではなく、混合する活性化合物の種類、病害虫の発生予察等に応じて相対的に広い範囲にわたり変えることができる。一般には、混合比は、例えば、(a)のイソチアニル1重量部に対して、(b)のフィプロニル又はエチプロールは0.02〜3重量部、好ましくは、0.05〜2.5重量部の範囲、そして(c)成分を加えてなる場合には、(c)成分は、0.5〜2重量部、好ましくは、1〜1.5重量部の範囲内で使用することができる。 In the combination composition of the present invention, the mixing ratio of each active ingredient is not limited and can be varied over a relatively wide range depending on the type of active compound to be mixed, the occurrence of pests, etc. it can. In general, the mixing ratio is, for example, 0.02 to 3 parts by weight, preferably 0.05 to 2.5 parts by weight of fipronil or etiprole of (b) with respect to 1 part by weight of isotianil of (a). When the range and (c) component are added, the (c) component can be used in the range of 0.5 to 2 parts by weight, preferably 1 to 1.5 parts by weight.
本発明に従い、(a)イソチアニル1重量部あたりの(b)フィプロニル又はエチプロールの重量部としてのさらなる混合比を使用することができる(与えられる順序で優先度が高くなる。):
0.02、0.05、0.075、0.1、0.15、0.2、0.3、0.4、0.5、0.6、0.7、0.8、0.9、1、1.1、1.2、1.3、1.4、1.5、1.6、1.7、1.8、1.9、2、2.1、2.2、2.3、2.4、2.5、2.6、2.7、2.8、2.9、3。
In accordance with the present invention, a further mixing ratio can be used as part by weight of (b) fipronil or ethiprole per part by weight of (a) isotianil (higher priority in the order given):
0.02, 0.05, 0.075, 0.1, 0.15, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0. 9, 1, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3.
成分(c)も含有される場合、本発明に従い、(a)イソチアニルの1重量部あたりの成分(c)の重量部としてのさらなる混合比を使用することができる(与えられる順序で優先度が高くなる。):
0.5、0.6、0.7、0.8、0.9、1、1.1、1.2、1.3、1.4、1.5、1.6、1.7、1.8、1.9、2。
If component (c) is also included, according to the present invention, further mixing ratios as parts by weight of component (c) per part by weight of (a) isothianyl can be used (priority in the order given). Higher):
0.5, 0.6, 0.7, 0.8, 0.9, 1, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.
本発明の組み合わせ組成物を使用するに当たっては、育苗箱に水稲種子を播種し、当該組成物を覆土前に施用する方法又は育苗箱の床土又は水稲種子を覆土する土に、当該組成物を混合する方法により、本田移植後の病害虫の防除を的確に行なうことができる。 In using the combination composition of the present invention, the seeds are sown in a seedling box, and the composition is applied to the soil before covering the paddy rice seeds or the floor soil of the seedling box or the method of applying the composition before covering the soil. By the method of mixing, pest control after Honda transplantation can be accurately performed.
本発明の組み合わせ組成物が防除の対照とする病害虫としては、以下のものを例示することができるが、これらに限定されるものではない。 Examples of the pests that are controlled by the combination composition of the present invention include the following, but are not limited thereto.
水稲害虫として
半翅目:ツマグロヨコバイ(Nephotettix cincticeps)、トビイロウンカ(Nilaparvata lugens)、ヒメトビウンカ(Laodelphax striatellus(Fallen))、セジロウンカ(Sogatella furcifera(Horvath))など。
As paddy rice pests: Hemiptera: Nephotettix cinchetics, Japanese planthopper (Nilaparvata lugens), Japanese planthopper (Laodedelfax stratiellas (Fallen)), White-tailed planthopper (Sotaharva).
甲虫目:イネドロオイムシ(Oulema oryzae(Kuwayama))、イネミズゾウムシ(Lissorhoptrus oryzophilus Kuschel)など。 Coleoptera: Rice beetle (Oulema oryzae (Kuwayama)), rice weevil (Lissorhoptrus oryzophilus Kuschel), etc.
鱗翅目:ニカメイチュウ(Chilo suppressalis(Walker))、コブノメイガ(Cnaphalocrocis medinalis(Guenee))、イネツトムシ(Parnara guttata(Bremex et Grey))など。 Lepidoptera: Nigella cypress (Chiro suppressalis (Walker)), Cnaphalocros medinalis (Guenee), Inetomi (Parnara guttata (Bremex et Grey)) and the like.
水稲病害として、イモチ病(Pyricularia oryzae)、紋枯病(Pellicularia sasakii)、サーコスポラ・ジャンセアナ(Cercospora janseana)、イネ赤色菌核病菌(Rhizoctonia oryzae)、小麦立ち枯れ病(Gaeumannomyces graminis var.graminis)、ネオボッシア・バルクラヤナ(Neovossia barclayana)、イネごま葉枯病菌(Bipolaris oryzae)、苗立枯病(Pythium sp.)、シバ類葉腐病菌(Rhizoctonia solani)、ワタカビ(Achlya sp.)および白絹病(Sclerotium rolfsii)、イネ褐色菌核病菌(Sclerotium oryzae)、イネごま葉枯病菌(Bipolaris oryzae)、黒しゅ病(Entyloma oryzae)、シバ類葉腐病菌(Rhizoctonia solani)、イネ白葉枯病(Xanthomonas campestris pv oryzae)など。 As paddy rice diseases, there are rice blast disease (Piculararia oryzae), coat blight (Pericularia sasakii), Cercospora jansiana, rice red fungus disease (Rhizoctonia oryzae), mincion, and wheat. Barbrayana (Neovossia barclayana), rice sesame leaf blight fungus (Bipolaris oryzae), seedling blight (Pythium sp.), Barley leaf rot fungus (Rhizoctonia solani), cotton fungus (Achlisti white silkworm) , Rice brown sclerotia fungus (Sclerot um oryzae), rice sesame leaf blight (Bipolaris oryzae), black Zhu disease (Entyloma oryzae), grasses leaf blight fungus (Rhizoctonia solani), rice bacterial leaf blight (Xanthomonas campestris pv oryzae), such as.
本発明によると、全ての植物および植物の部分を処理することができる。植物は、本明細書においては、望ましい、および望ましくない野生植物、品種および植物品種などの全ての植物および植物個体群(植物品種又は植物育種業者の権利によって保護されるにせよ又は保護されないにせよ)を意味する。品種および植物品種は、倍加半数体、原形質融合、無作為および定方向突然変異誘発、分子又は遺伝子マーカーの使用によって又は生物工学および遺伝子工学法によってなど、1以上のバイオテクノロジー法により補助又は補完され得る従来の繁殖および育種法により得られる植物であり得る。植物の部分とは、植物の全ての地上および地下部分および器官、例えば、苗条、葉、花および根など(その例としては、葉、針状葉、茎、幹、花、子実体、果実および種子ならびに根、塊茎および根茎等が挙げられる。)を意味する。収穫された植物および栄養繁殖および生殖繁殖(generative propagation)物質、例えば、挿穂、球茎、根茎、匍匐枝および種子も植物の部分に属する。 According to the invention, all plants and plant parts can be treated. Plants as used herein are all plants and plant populations (whether protected or not protected by the rights of plant varieties or plant breeders, including desirable and undesirable wild plants, varieties and plant varieties). ). Varieties and plant varieties are supplemented or supplemented by one or more biotechnological methods, such as by doubling haploids, protoplast fusion, random and directed mutagenesis, using molecular or genetic markers or by biotechnology and genetic engineering methods It can be a plant obtained by conventional breeding and breeding methods that can be done. Plant parts include all aboveground and underground parts and organs of plants, such as shoots, leaves, flowers and roots (examples include leaves, needles, stems, stems, flowers, fruit bodies, fruits and And seeds, roots, tubers and rhizomes). Harvested plants and vegetative and reproductive propagation materials such as cuttings, corms, rhizomes, toothpicks and seeds also belong to the plant part.
本発明による方法によって保護することができる植物の中でも、主要な農作物として、トウモロコシ、ダイズ、綿花、アブラナ属脂肪種子、例えばセイヨウアブラナ(Brassica napus)(例えばキャノーラ)、カブ(Brassica rapa)、カラシナ(B.juncea)(例えばマスタード)およびアビシニアカラシ(Brassica carinata)など、コメ、コムギ、サトウダイコン、サトウキビ、オートムギ、ライムギ、オオムギ、キビ、ライコムギ、亜麻、蔓および様々な植物分類群の様々な果実および野菜、例えば、バラ科(Rosaceae sp.)(例えば、リンゴおよびナシなどの種果実、ならびに、アンズ、サクランボ、アーモンドおよび桃などの石果、イチゴなどのベリー類、)、リベシオイデ(Ribesioidae sp.)、クルミ科(Juglandaceae sp.)、カバノキ科(Betulaceae sp.)、ウルシ科(Anacardiaceae sp.)、ブナ科(Fagaceae sp.)、クワ科(Moraceae sp.)、モクセイ科(Oleaceae sp.)、マタタビ科(Actinidaceae sp.)、クスノキ科(Lauraceae sp.)、バショウ科(Musaceae sp.)(例えば、バナナ樹および植え付け)、アカネ科(Rubiaceae sp.)(例えばコーヒー)、ツバキ科(Theaceae sp.)、アオギリ科(Sterculiceae sp.)、ミカン科(Rutaceae sp.)(例えば、レモン、オレンジおよびグレープフルーツ);ナス科(Solanaceae sp.)(例えばトマト、ジャガイモ、コショウ、ナス)、ユリ科(Liliaceae sp.)、キク科(Compositiae sp.)(例えば、レタス、アーティチョークおよびチコリ−根チコリ、エンダイブ又はチコリを含む。)、セリ科(Umbelliferae sp.)(例えば、ニンジン、パセリ、セロリおよび根用セロリ)、ウリ科(Cucurbitaceae sp.)(例えば、キュウリ−ピックルキュウリ、カボチャ、スイカ、ウリおよびメロンを含む。)、ネギ科(Alliaceae sp.)(例えばタマネギおよびリーク)、アブラナ科(Cruciferae sp.)(例えば、白キャベツ、紫キャベツ、ブロッコリー、カリフラワー、芽キャベツ、チンゲンサイ、コールラビ、ダイコン、セイヨウワサビ、クレス、ハクサイ)、マメ科(Leguminosae sp.)(例えば、ピーナツ、エンドウおよびマメ類−インゲンマメ(clibming beans)およびソラマメ等)、アカザ科(Chenopodiaceae sp.)(例えば、フダンソウ、スピナッチビート、ホウレンソウ、ビートルート)、アオイ科(Malvaceae)(例えばオクラ)、クサスギカズラ科(Asparagaceae)(例えばアスパラガス);園芸および森林作物;鑑賞植物;ならびにこれらの作物の遺伝子組み換え相同物を挙げることができる。 Among the plants that can be protected by the method according to the invention, the main crops include corn, soybean, cotton, oilseed rape, such as Brassica napus (for example canola), turnip (Brassica rapa), mustard ( Various fruits of rice, wheat, rye, barley, millet, triticale, flax, vine and various plant taxa, such as B. juncea (e.g. mustard) and Abyssinia mustard (Brassica carinata) Vegetables such as Rosaceae sp. (Eg, seed fruits such as apples and pears, and stone fruits such as apricots, cherries, almonds and peaches, berries such as strawberries), Ribesioidae sp., Walnut family (Juglandaceae sp.), Birch family (Betulaceae sp.), Urushi family (Anacardiaceae sp.), Beech family (Fagaceae sp.), Mulberry family (Spaceae, Sp. Family) Oleaceae sp.), Actinidaceae sp., Lauraceae sp., Musaceae sp. (Eg, banana trees and planting), Rubiaceae sp. (Eg, coffee), camellia Theaceae (Steraceae sp.), Sterculaeae sp., Rutaceae sp. (Eg, lemon, orange and gray) Solaaceae sp. (Eg, tomato, potato, pepper, eggplant), Lilyaceae sp., Compositae sp. (Eg, lettuce, artichoke and chicory-root chicory, endive or Chicory), umbelliferae sp. (Eg carrot, parsley, celery and root celery), cucurbitaceae sp. (Eg cucumber-pickle cucumber, pumpkin, watermelon, cucumber and melon) ), Alliaceae sp. (Eg, onions and leaks), Brassicaceae (Cruciferae sp.) (Eg, white cabbage, purple cabbage, broccoli, cauliflower, brussels sprouts) , Bok choy, kohlrabi, radish, horseradish, cress, Chinese cabbage), legumes (Leguminosae sp. ) (E.g. peanuts, peas and legumes-such as bean beans and faba beans), Chenopodiaceae sp. (E.g. chard, spinach beet, spinach, beetroot), malvaceae (e.g. malvaceae) ), Asparagaceae (eg asparagus); horticulture and forest crops; ornamental plants; and genetically modified homologues of these crops.
遺伝的改変生物(GMO)、例えば植物又は種子、の処理において、本発明による処理方法を使用することができる。遺伝的改変植物(又はトランスジェニック植物)は、異種遺伝子が安定的にゲノムに組み込まれている植物である。「異種」遺伝子の表現は、基本的に、植物の外から提供されている又は構築されている遺伝子を意味し、核に導入された場合、葉緑体又はミトコンドリアゲノムは、関心のあるタンパク質又はポリペプチドを発現させることにより、又は植物中に存在する他の遺伝子を下方制御するもしくは抑制することにより(例えば、アンチセンス技術、コサプレッション技術又はRNA干渉−RNAi技術を用いて)、形質転換された植物の農業的又はその他の特性を新しくする又は向上させる。ゲノムに位置する異種遺伝子はまたトランス遺伝子とも呼ばれる。植物ゲノムのその特定の位置により定義されるトランス遺伝子は、形質転換又はトランスジェニックイベント(transgenic event)と呼ばれる。 In the treatment of genetically modified organisms (GMO), for example plants or seeds, the treatment method according to the invention can be used. A genetically modified plant (or transgenic plant) is a plant in which a heterologous gene is stably integrated into the genome. The expression of a “heterologous” gene basically means a gene that has been provided or constructed from outside the plant, and when introduced into the nucleus, the chloroplast or mitochondrial genome is the protein of interest or Transformed by expressing the polypeptide or by down-regulating or suppressing other genes present in the plant (eg, using antisense technology, co-suppression technology or RNA interference-RNAi technology) Renew or improve the agricultural or other characteristics of the plant. A heterologous gene located in the genome is also called a transgene. A transgene defined by its specific location in the plant genome is called a transformation or transgenic event.
植物種又は植物品種、その場所および成長条件(土壌、気候、植生期間、栄養)に依存して、本発明による処理の結果、超加算(「相乗」)効果も生じ得る。従って、例えば、実際に予想される効果を上回り、散布量を低下させ、および/又は活性スペクトルを拡大させ、および/又は本発明に従って用いることができる活性化合物および組成物の活性を向上させ、植物の成長をより良好にし、高温又は低温に対する耐性を向上させ、乾燥又は水又は土壌塩含量に対する耐性を向上させ、開花成績を向上させ、収穫を促進し、成熟を加速し、収穫量を向上させ、果実を大型化し、植物の高さを伸長させ、葉の緑色を濃くし、開花を早め、収穫産物の品質および/又は栄養価を高め、果実内の糖濃度を高め、収穫産物の貯蔵安定性および/又は処理性を向上させることが可能である。 Depending on the plant species or plant varieties, their location and growth conditions (soil, climate, vegetation period, nutrients), the treatment according to the invention can also result in superadditive (“synergistic”) effects. Thus, for example, by exceeding the expected effect, reducing the spread rate and / or expanding the activity spectrum and / or improving the activity of the active compounds and compositions that can be used according to the invention, Better growth, improve tolerance to high or low temperatures, improve tolerance to dryness or water or soil salt content, improve flowering performance, promote harvest, accelerate maturity, improve yield , Increase fruit size, lengthen plant height, darken leaves green, speed flowering, improve quality and / or nutritional value of harvested products, increase sugar concentration in fruits, stable storage of harvested products And / or processability can be improved.
ある一定の散布量で、本発明による活性化合物の組み合わせはまた、植物における強化効果も有し得る。従って、これらはまた、望ましくない微生物による攻撃からの植物の防御システムを動かすのにも適切である。必要に応じて、これは、例えば真菌に対して、本発明による組み合わせの活性を増強させることの理由の1つであり得る。植物強化(耐性誘導)物質は、本発明の内容において、望ましくない微生物が連続的に接種される場合、処理済植物がこれらの微生物に対して十分な程度の耐性を示すような方法で、植物の防御システムを刺激することができる物質又は物質の組み合わせを意味するものとして理解されたい。この場合、望ましくない微生物は、病害虫を意味するものとして理解されたい。このようにして、処理後のある一定期間内で上述の病原体による攻撃から植物を保護するために、本発明による物質を使用することができる。保護が有効である期間は、通常、活性化合物での植物の処理後、1から10日間、好ましくは1から7日間に及ぶ。 At a certain application rate, the active compound combinations according to the invention can also have a strengthening effect in plants. They are therefore also suitable for moving the plant's defense system from attack by unwanted microorganisms. If necessary, this can be one of the reasons for enhancing the activity of the combination according to the invention, for example against fungi. In the context of the present invention, plant strengthening (tolerance-inducing) substances are produced in such a way that, when undesired microorganisms are continuously inoculated, the treated plants exhibit a sufficient degree of resistance to these microorganisms. It should be understood as meaning a substance or a combination of substances that can stimulate the defense system. In this case, undesirable microorganisms are to be understood as meaning pests. In this way, the substances according to the invention can be used to protect plants from attack by the above mentioned pathogens within a certain period of time after treatment. The period during which the protection is effective usually ranges from 1 to 10 days, preferably from 1 to 7 days, after treatment of the plant with the active compound.
好ましくは本発明により処理すべき植物および植物品種には、これらの植物に対して特に有利となり、有用な特徴を与える遺伝物質を有する全ての植物(繁殖および/又はバイオテクノロジーの手法により得られるもの)が含まれる。 Preferably, the plants and plant varieties to be treated according to the invention are all advantageous to these plants and all plants with genetic material that give useful characteristics (those obtained by breeding and / or biotechnological techniques) ) Is included.
本発明によりまた好ましくは処理すべき植物および植物品種は、1以上の生物ストレスに対して耐性があり、即ち、この植物は、病害動物および菌に対して、例えば、線虫、昆虫、ダニ、植物病原菌、細菌、ウイルスおよび/又はウイロイドなどに対して、より高い防御を示す。 The plants and plant varieties to be treated according to the invention also preferably are resistant to one or more biological stresses, ie the plants are resistant to disease animals and fungi, for example nematodes, insects, mites, Higher protection against phytopathogenic bacteria, bacteria, viruses and / or viroids.
本発明によりまた好ましくは処理し得る植物および植物品種は、1以上の非生物ストレスに対して耐性がある植物である。非生物ストレス状態には、例えば、乾燥、低温への曝露、熱への曝露、浸透ストレス、湛水、高塩濃度土壌、高ミネラルへの曝露、オゾン曝露、高照度曝露、窒素栄養素の利用制限、リン栄養素の利用制限、日陰の忌避が含まれ得る。 Plants and plant varieties that can also preferably be treated according to the invention are plants that are resistant to one or more abiotic stresses. Non-biological stress conditions include, for example, dryness, low temperature exposure, heat exposure, osmotic stress, flooding, high salt soil, high mineral exposure, ozone exposure, high light exposure, and limited use of nitrogen nutrients May include restricted use of phosphorus nutrients, shade avoidance.
本発明によりまた処理し得る植物および植物品種は、回収特性が向上していることを特徴とする植物である。この植物において回収が向上することは、例えば、植物生理、成長および発達の促進、例えば、水分利用効率、効率のよい水分保持、窒素使用の向上、炭素同化の向上、光合成の向上、発芽効率向上および成熟促進など、の結果であり得る。収穫はさらに、以下に限定されないが、早咲き、ハイブリッド種子生成のための開花調節、苗の活力、植物の大きさ、節間数および距離、根の成長、種子の大きさ、果実の大きさ、鞘の大きさ、鞘又は穂数、鞘又は穂あたりの種子数、種子の質量、登熟の向上、種子飛散の低下、鞘裂開の減少および耐倒伏性を含む(ストレスおよび非ストレス条件下での)植物構造の改善によって影響を受け得る。さらなる収穫特性には、種子組成、例えば、炭水化物含量、タンパク質含量、脂肪含量および組成、栄養価、抗栄養化合物の減少、加工性の向上および保存安定性の向上が含まれる。 Plants and plant varieties that can also be treated according to the present invention are plants characterized by improved recovery characteristics. Improvement in recovery in this plant means, for example, promotion of plant physiology, growth and development, for example, water use efficiency, efficient water retention, improvement of nitrogen use, improvement of carbon assimilation, improvement of photosynthesis, improvement of germination efficiency And the result of promoting maturity. Harvesting further includes but is not limited to early blooming, flowering regulation for hybrid seed production, seedling vitality, plant size, internode number and distance, root growth, seed size, fruit size, Includes pod size, number of pods or spikes, number of seeds per pod or spike, seed mass, improved ripening, reduced seed dispersal, reduced dehiscence and lodging resistance (under stress and non-stress conditions Can be affected by improvements in plant structure. Additional harvest characteristics include seed composition, eg, carbohydrate content, protein content, fat content and composition, nutritional value, reduced anti-nutritive compounds, improved processability and improved storage stability.
本発明により処理し得る植物は、結果として一般に収穫率が高くなり、強く、健康で生物および非生物ストレスに対する耐性が向上している、雑種強勢又はハイブリッド強勢の特性を既に発現するハイブリッド植物である。このような植物は、通常、同系交配の雄性不稔親株(雌親)と別の同系交配雄性稔性親株(雄親)との交配により作製される。ハイブリッド種子は、通常、雄性不稔植物から回収され、農家に販売される。雄性不稔植物は、時として(例えばトウモロコシにおいて)、房を取り除く(即ち、機械的に雄性生殖器(又は雄花)を除去する。)ことにより作製され得るが、より一般的には、雄性不稔性は、植物ゲノムにおける遺伝的決定の結果である。その場合、および特に種子がハイブリッド植物から収穫しようとする所望の産物である場合、一般に、ハイブリッド植物において雄性稔性が完全に回復していることを確実にすることは有用である。これは、雄性不稔性に関与する遺伝的決定基を含有するハイブリッド植物において雄性稔性を回復することができる適切な稔性回復遺伝子を雄親が有することを確実にすることにより行うことができる。雄性不稔性に対する遺伝的決定基は細胞質に位置し得る。細胞質雄性不稔(CMS)の例は、例えば、アブラナ科(Brassica species)(WO92/05251、WO95/09910、WO98/27806、WO05/002324、WO06/021972およびUS6,229,072号)で記載されている。しかし、雄性不稔に対する遺伝的決定基は核ゲノムにも位置し得る。遺伝子工学などの植物バイオテクノロジー法によって雄性不稔植物を得ることもできる。雄性不稔植物を得る特に有用な手段は、例えばWO89/10396に記載されており、ここでは、例えば雄蕊のじゅうたん組織細胞においてバルナーゼなどのリボヌクレアーゼが選択的に発現される。次に、バルスターなどのリボヌクレアーゼ阻害剤のじゅうたん組織細胞での発現によって、稔性を回復させることができる(例えばWO91/02069)。 Plants that can be treated according to the present invention are hybrid plants that already express the characteristics of hybrid or hybrid stresses, which generally result in higher yields, are stronger, have better health and improved resistance to biological and abiotic stresses. . Such plants are usually produced by crossing an inbred male sterile parent strain (female parent) with another inbred male fertile parent strain (male parent). Hybrid seed is usually recovered from male sterile plants and sold to farmers. Male sterile plants can sometimes be produced (eg in corn) by removing the tufts (ie, mechanically removing the male genital organs (or male flowers)), but more commonly, male sterility. Sex is the result of genetic determination in the plant genome. In that case, and especially when the seed is the desired product to be harvested from the hybrid plant, it is generally useful to ensure that male fertility is fully restored in the hybrid plant. This can be done by ensuring that the male parent has an appropriate fertility recovery gene that can restore male fertility in a hybrid plant containing genetic determinants involved in male sterility. it can. Genetic determinants for male sterility can be located in the cytoplasm. Examples of cytoplasmic male sterility (CMS) are described, for example, in Brassica species (WO 92/05251, WO 95/09910, WO 98/27806, WO 05/002324, WO 06/021972 and US 6,229,072). ing. However, genetic determinants for male sterility can also be located in the nuclear genome. Male sterile plants can also be obtained by plant biotechnology methods such as genetic engineering. A particularly useful means of obtaining male sterile plants is described, for example, in WO 89/10396, where a ribonuclease such as barnase is selectively expressed in, for example, stamen carpet tissue cells. Next, fertility can be restored by the expression of ribonuclease inhibitors such as balsters in carpet tissue cells (eg WO 91/02069).
本発明により処理し得る(遺伝子工学などの植物バイオテクノロジー法によって得られる)植物又は植物品種は、除草剤−耐性植物、即ち、1以上のある種の除草剤に耐性となるようにされた植物である。遺伝子形質転換又は、このような除草剤耐性を与える突然変異を含有する植物の選択の何れかによって、このような植物を得ることができる。 Plants or plant varieties (obtained by plant biotechnology methods such as genetic engineering) that can be treated according to the present invention are herbicide-tolerant plants, i.e. plants that are made tolerant to one or more certain herbicides. It is. Such plants can be obtained either by genetic transformation or by selection of plants containing mutations that confer such herbicide tolerance.
除草剤耐性植物は、例えば、グリホサート耐性植物、即ち、除草剤グリホサート又はその塩に耐性となるようにされた植物である。様々な手段を通じて、植物をグリホサートに対して耐性にすることができる。例えば、酵素5−エノールピルビルシキミ酸−3−リン酸シンターゼ(EPSPS)をコードする遺伝子を用いて植物を形質転換することによって、グリホサート耐性植物を得ることができる。このようなEPSPS遺伝子の例は、ネズミチフス菌(Salmonella typhimurium)AroA遺伝子(突然変異CT7)(Comaiら、1983、Science 221、370−371)、細菌アグロバクテリウム(Agrobacterium sp.)のCP4遺伝子(Barryら、1992、Curr.Topics Plant Physiol.7、139−145)、ペチュニアEPSPSをコードする遺伝子(Shahら、1986、Science 233、478−481)、トマトEPSPS(Gasserら、1988、J.Biol.Chem.263、4280−4289)又はシコクビエ(Eleusine)EPSPS(WO01/66704)である。これはまた、例えばEP0837944、WO00/66746、WO00/66747又はWO02/26995に記載のような突然変異EPSPSでもあり得る。米国特許第5,776,760号および同第5,463,175号に記載のように、グリホサートオキシド−レダクターゼ酵素をコードする遺伝子を発現させることによって、グリホサート耐性植物を得ることもできる。例えばWO02/36782、WO03/092360、WO05/012515およびWO07/024782に記載のように、グリホサートアセチルトランスフェラーゼ酵素をコードする遺伝子を発現させることによって、グリホサート耐性植物を得ることもできる。例えば、WO01/024615又はWO03/013226に記載のように、上述の遺伝子の天然の突然変異を含有する植物を選択することによって、グリホサート耐性植物を得ることもできる。 A herbicide-tolerant plant is, for example, a glyphosate-tolerant plant, that is, a plant adapted to be resistant to the herbicide glyphosate or a salt thereof. Plants can be made resistant to glyphosate through various means. For example, glyphosate-tolerant plants can be obtained by transforming plants with a gene encoding the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). Examples of such EPSPS genes include the Salmonella typhimurium AroA gene (mutant CT7) (Comai et al., 1983, Science 221, 370-371), and the CP4 gene of the Agrobacterium sp. 1992, Curr. Topics Plant Physiol. 7, 139-145), a gene encoding Petunia EPSPS (Shah et al., 1986, Science 233, 478-481), tomato EPSPS (Gasser et al., 1988, J. Biol. Chem). 263, 4280-4289) or Eleusine EPSPS (WO 01/66704). It can also be a mutant EPSPS as described for example in EP0837944, WO00 / 66746, WO00 / 66747 or WO02 / 26995. Glyphosate-tolerant plants can also be obtained by expressing a gene encoding the glyphosate oxide-reductase enzyme as described in US Pat. Nos. 5,776,760 and 5,463,175. For example, as described in WO02 / 36782, WO03 / 092360, WO05 / 012515 and WO07 / 024782, glyphosate-tolerant plants can be obtained by expressing a gene encoding a glyphosate acetyltransferase enzyme. For example, as described in WO01 / 024615 or WO03 / 013226, glyphosate-tolerant plants can be obtained by selecting plants that contain natural mutations of the above genes.
その他の除草剤耐性植物は、例えば、ビアラホス、ホスフィノトリシン又はグルホシネートなど、酵素グルタミンシンターゼを阻害する除草剤に対して耐性にされている植物である。除草剤を解毒する酵素又は阻害に耐性のある突然変異グルタミンシンターゼ酵素を発現させることによって、このような植物を得ることができる。あるこのような効果的な解毒酵素は、ホスフィノトリシンアセチルトランスフェラーゼ(ストレプトミセス(Streptomyces species)由来のbar又はpatタンパク質など)をコードする酵素である。外来ホスフィノトリシンアセチルトランスフェラーゼを発現する植物は、例えば、米国特許第5,561,236号;同第5,648,477号;同第5,646,024号;同第5,273,894号;同第5,637,489号;同第5,276,268号;同第5,739,082号;同第5,908,810号および同第7,112,665号に記載されている。 Other herbicide-tolerant plants are plants that have been made resistant to herbicides that inhibit the enzyme glutamine synthase, such as bialaphos, phosphinotricin or glufosinate, for example. Such plants can be obtained by expressing an enzyme that detoxifies the herbicide or a mutant glutamine synthase enzyme that is resistant to inhibition. One such effective detoxifying enzyme is an enzyme that encodes a phosphinothricin acetyltransferase (such as a bar or pat protein from Streptomyces species). Plants expressing exogenous phosphinothricin acetyltransferase include, for example, US Pat. Nos. 5,561,236; 5,648,477; 5,646,024; 5,273,894. No. 5,637,489; No. 5,276,268; No. 5,739,082; No. 5,908,810 and No. 7,112,665. .
さらなる除草剤耐性植物はまた、酵素ヒドロキシフェニルピルビン酸ジオキシゲナーゼ(HPPD)を阻害する除草剤に対して耐性にされている植物でもある。ヒドロキシフェニルピルビン酸ジオキシゲナーゼは、パラ−ヒドロキシフェニルピルビン酸(HPP)がホモゲンチジン酸に変換される反応を触媒する酵素である。WO96/38567、WO99/24585およびWO99/24586に記載のように、天然の耐性HPPD酵素をコードする遺伝子又は突然変異HPPD酵素コードする遺伝子によって、HPPD−阻害剤に耐性のある植物を形質転換することができる。HPPD阻害剤に対する耐性はまた、HPPD阻害剤によるネイティブHPPD酵素の阻害にもかかわらずホモゲンチシン酸の形成を可能にするある種の酵素をコードする遺伝子で植物を形質転換することによっても得ることができる。このような植物および遺伝子は、WO99/34008およびWO02/36787に記載されている。WO2004/024928に記載のように、HPPD−耐性をコードする遺伝子に加えて、酵素プレフェン酸デヒドロゲナーゼをコードする遺伝子で植物を形質転換することによって、HPPD阻害剤に対する植物の耐性を向上させることもできる。 Further herbicide-tolerant plants are also plants that have been rendered tolerant to herbicides that inhibit the enzyme hydroxyphenylpyruvate dioxygenase (HPPD). Hydroxyphenylpyruvate dioxygenase is an enzyme that catalyzes a reaction in which para-hydroxyphenylpyruvate (HPP) is converted to homogentisic acid. Transforming plants resistant to HPPD inhibitors with a gene encoding a naturally resistant HPPD enzyme or a gene encoding a mutant HPPD enzyme as described in WO 96/38567, WO 99/24585 and WO 99/24586 Can do. Resistance to HPPD inhibitors can also be obtained by transforming plants with genes encoding certain enzymes that allow the formation of homogentisic acid despite the inhibition of native HPPD enzymes by HPPD inhibitors. . Such plants and genes are described in WO99 / 34008 and WO02 / 36787. As described in WO 2004/024928, in addition to the gene encoding HPPD-resistance, the plant resistance to HPPD inhibitors can also be improved by transforming the plant with a gene encoding the enzyme prefenate dehydrogenase. .
またさらなる除草剤耐性植物は、アセト乳酸シンターゼ(ALS)阻害剤に対して耐性にされている植物である。既知のALS−阻害剤には、例えば、スルホニル尿素、イミダゾリノン、トリアゾロピリミジン、プリミジニオキシ(pryimidinyoxy)(チオ)ベンゾエートおよび/又はスルホニルアミノカルボニルトリアゾリノン除草剤が含まれる。ALS酵素(アセトヒドロキシ酸シンターゼ、AHASとしても知られる。)における様々な突然変異は、例えば、TranelおよびWright(2002、Weed Science 50:700−712)において、また、米国特許第5,605,01号、同第5,378,824号、同第5,141,870号および同第5,013,659号においても記載のように、様々な除草剤および除草剤群に対する耐性を与えることが知られている。スルホニル尿素耐性植物およびイミダゾリノン耐性植物の作製は、米国特許第5,605,011号;同第5,013,659号;同第5,141,870号;同第5,767,361号;同第5,731,180号;同第5,304,732号;同第4,761,373号;同第5,331,107号;同第5,928,937号および同第5,378,824号;および国際公開WO96/33270に記載されている。その他のイミダゾリノン耐性植物は、例えばWO2004/040012、WO2004/106529、WO2005/020673、WO2005/093093、WO2006/007373、WO2006/015376、WO2006/024351およびWO2006/060634にも記載されている。さらなるスルホニル尿素−およびイミダゾリノン−耐性植物は例えばWO07/024782にも記載されている。 Still further herbicide tolerant plants are plants that have been rendered tolerant to acetolactate synthase (ALS) inhibitors. Known ALS-inhibitors include, for example, sulfonylureas, imidazolinones, triazolopyrimidines, primimidinoxy (thio) benzoates and / or sulfonylaminocarbonyltriazolinone herbicides. Various mutations in the ALS enzyme (also known as acetohydroxyacid synthase, AHAS) are described, for example, in Train and Wright (2002, Weed Science 50: 700-712) and in US Pat. No. 5,605,01. No. 5,378,824, 5,141,870 and 5,013,659 are known to confer resistance to various herbicides and herbicide groups. It has been. Production of sulfonylurea and imidazolinone resistant plants is described in US Pat. Nos. 5,605,011; 5,013,659; 5,141,870; 5,767,361; No. 5,731,180; No. 5,304,732; No. 4,761,373; No. 5,331,107; No. 5,928,937 and No. 5,378 , 824; and International Publication No. WO 96/33270. Other imidazolinone-tolerant plants are also described, for example, in WO2004 / 040012, WO2004 / 106529, WO2005 / 020673, WO2005 / 093093, WO2006 / 007373, WO2006 / 015376, WO2006 / 024351 and WO2006 / 060634. Further sulfonylurea- and imidazolinone-tolerant plants are also described, for example in WO07 / 024782.
例えば、ダイズに対して米国特許第5,084,082号、コメに対してWO97/41218、サトウダイコンに対して米国特許第5,773,702号およびWO99/057965、レタスに対して米国特許第5,198,599号又はヒマワリに対してWO01/065922に記載のように、誘導された突然変異誘発、除草剤存在下での細胞培養における選択又は突然変異育種によって、イミダゾリノンおよび/又はスルホニル尿素耐性のその他の植物を得ることができる。 For example, US Pat. No. 5,084,082 for soybeans, WO 97/41218 for rice, US Pat. Nos. 5,773,702 and WO 99/057965 for sugar beets, US Pat. Imidazolinone and / or sulfonylurea by induced mutagenesis, selection in cell culture in the presence of herbicides or mutation breeding as described in WO 01/065922 for sunflowers, 5,198,599 or sunflower Other plants that are resistant can be obtained.
(遺伝子工学などの植物バイオテクノロジー法によって得た)本発明によりまた処理し得る植物又は植物品種は、昆虫耐性トランスジェニック植物、即ちある種の標的昆虫による攻撃に耐性となるようにされた植物である。形質転換によって又はこのような昆虫耐性を与える突然変異を含有する植物の選択によって、このような植物を得ることができる。 Plants or plant varieties that can also be treated according to the present invention (obtained by plant biotechnology methods such as genetic engineering) are insect resistant transgenic plants, ie plants that have been made resistant to attack by certain target insects. is there. Such plants can be obtained by transformation or by selection of plants containing mutations that confer such insect resistance.
本明細書中で使用する場合、「昆虫耐性トランスジェニック植物」には、次のものをコードするコード配列を含む少なくとも1つのトランス遺伝子を含有するあらゆる植物が含まれる:
1)バチルス・チューリンゲンシス(Bacillus thuringiensis)由来の殺虫結晶タンパク質又はその殺虫部分、例えばCrickmoreら(1998、Microbiology and Molecular Biology Reviews、62:807−813)に列挙される殺虫結晶タンパク質など(バチルス・チューリンゲンシス毒素命名法において、Crickmoreら(2005)により更新、オンライン、http://www.lifesci.sussex.ac.uk/Home/Neil_Crickmore/Bt/)又はその殺虫部分、例えばCryタンパク質クラスCry1Ab、Cry1Ac、Cry1F、Cry2Ab、Cry3Aa又はCry3Bbのタンパク質又はその殺虫部分;又は
2)バチルス・チューリンゲンシス由来の結晶タンパク質又はバチルス・チューリンゲンシス由来の第二のその他の結晶タンパク質存在下で殺虫性であるその一部又はCry34およびCry35結晶タンパク質から構成されるバイナリートキシン(binary toxin)などのその一部(Moellenbeckら、2001.Nat.Biotechnol.19:668−72;Schnepfら、2006、Applied Environm.Microbiol.71.1765−1774);又は
3)バチルス・チューリンゲンシス由来の様々な殺虫結晶タンパク質の一部を含むハイブリッド殺虫タンパク質、例えば上記1)のタンパク質のハイブリッド又は上記2)のタンパク質のハイブリッド、例えばトウモロコシ・イベントMON98034(WO2007/027777)により産生されるCry1A.105タンパク質;又は
4)上記A1)からA3)の何れか1つのタンパク質(標的昆虫種に対するより高い殺虫活性を得るために、および/又は影響を受ける標的昆虫種の範囲を広げるために、および/又はクローニングもしくは形質転換中にコードDNAに導入される変化ゆえに、いくつか、特に1から10の、アミノ酸が別のアミノ酸により置換されている。)、例えば、トウモロコシ・イベントMON863又はMON88017におけるCry3Bb1タンパク質又はトウモロコシ・イベントMIR604におけるCry3Aタンパク質;
5)バチルス・チューリンゲンシスもしくはバチルス・セレウス(Bacillus cereus)由来の殺虫分泌タンパク質又はその殺虫部分、例えば、http://www.lifesci.sussex.ac.uk/home/Neil_Crickmore/Bt/vip.htmlで列挙される植物性殺虫(VIP)タンパク質、例えば、VIP3Aaタンパク質クラス;又は
6)バチルス・チューリンゲンシスもしくはB.セレウス由来の第二の分泌タンパク質存在下で殺虫性であるバチルス・チューリンゲンシスもしくはバチルス・セレウス(Bacillus cereus)由来の分泌タンパク質、例えば、VIP1AおよびVIP2Aタンパク質から構成されるバイナリートキシン(binary toxin)(WO94/21795);又は
7)バチルス・チューリンゲンシスもしくはバチルス・セレウス由来の異なる分泌タンパク質由来の部分を含むハイブリッド殺虫タンパク質、例えば、上記1)のタンパク質のハイブリッドもしくは上記2)のタンパク質のハイブリッド;又は
8)上記1)から3)の何れか1つのタンパク質(標的昆虫種に対するより高い殺虫活性を得るために、および/又は影響を受ける標的昆虫種の範囲を広げるために、および/又はクローニング又は形質転換中にコードDNAに導入される変化ゆえに、いくつか、特に1から10の、アミノ酸が別のアミノ酸により置換されている。(一方で依然として殺虫タンパク質をコードしている。))、コットン・イベントCOT102のVIP3Aaタンパク質など。
As used herein, an “insect-resistant transgenic plant” includes any plant containing at least one transgene that includes a coding sequence that encodes:
1) Insecticidal crystal protein derived from Bacillus thuringiensis or an insecticidal portion thereof, such as the insecticidal crystal protein listed in Crickmore et al. (1998, Microbiology and Molecular Biology Reviews, 62: 807-813). In the cis-toxin nomenclature, updated by Crickmore et al. (2005), online, http://www.lifeci.sussex.ac.uk/Home/Neil_Crickmore/Bt/) or its insecticidal part, eg Cry protein class Cry1Ab, Cry1Ac, Cry1F, Cry2Ab, Cry3Aa or Cry3Bb protein or insecticide thereof Or 2) a binary toxin composed of a crystal protein from Bacillus thuringiensis or a part thereof that is insecticidal in the presence of a second other crystal protein from Bacillus thuringiensis or a Cry34 and Cry35 crystal protein ( (part of binary toxin) (Moellenbeck et al., 2001. Nat. Biotechnol. 19: 668-72; Schnepf et al., 2006, Applied Environm. Microbiol. 71.1765-1774); or 3) from Bacillus thuringiensis Hybrid insecticidal proteins comprising a portion of various insecticidal crystal proteins, such as the protein hybrids of 1) above or the protein hybrids of 2) above, such as corn Cry1A produced by Cosi event MON98034 (WO2007 / 027777). 105 protein; or 4) any one of the proteins A1) to A3) above (to obtain higher insecticidal activity against the target insect species and / or to expand the range of affected target insect species, and / or Or, due to changes introduced into the coding DNA during cloning or transformation, some, especially 1 to 10, amino acids have been replaced by another amino acid)), eg Cry3Bb1 protein in corn event MON863 or MON88017 or Cry3A protein in corn event MIR604;
5) Insecticidal protein derived from Bacillus thuringiensis or Bacillus cereus or its insecticidal part, for example http: // www. lifesci. sussex. ac. uk / home / Neil_Crickmore / Bt / vip. plant insecticidal (VIP) proteins listed in html, eg VIP3Aa protein class; or 6) Bacillus thuringiensis or B. Binary toxins composed of secreted proteins from Bacillus thuringiensis or Bacillus cereus that are insecticidal in the presence of a second secreted protein from Cereus, such as VIP1A and VIP2A proteins (WO94) / 21795); or 7) a hybrid insecticidal protein comprising portions derived from different secreted proteins from Bacillus thuringiensis or Bacillus cereus, eg, a hybrid of the protein of 1) above or a hybrid of the protein of 2) above; or 8) In order to obtain a higher insecticidal activity against the target insect species and / or to expand the range of affected target insect species, any one of the above 1) to 3) And / or due to changes introduced into the coding DNA during cloning or transformation, some, especially 1 to 10, amino acids have been replaced by another amino acid (while still encoding an insecticidal protein). )), VIP3Aa protein of cotton event COT102.
言うまでもなく、昆虫耐性トランスジェニック植物にはまた、本明細書中で使用する場合、上記クラス1から8の何れか1つのタンパク質をコードする遺伝子の組み合わせを含む何らかの植物も含まれる。ある実施形態において、昆虫耐性植物は、様々な標的昆虫種に向けられた様々なタンパク質を使用する場合、影響を受ける標的昆虫種の範囲を広げるために、又は、同じ標的昆虫種に対して殺虫性があるが様々な作用様式を有する様々なタンパク質を使用することによって(例えば、昆虫において様々な受容体結合部位に結合することなど)、植物に対する昆虫耐性の発達を遅延させるために、上記クラス1から8の何れか1つのタンパク質をコードする複数のトランス遺伝子を含有する。 Needless to say, insect-resistant transgenic plants, as used herein, also include any plant that contains a combination of genes that encode any one of the above classes 1-8 proteins. In certain embodiments, insect-resistant plants use insecticides to broaden the range of affected target insect species when using different proteins directed to different target insect species, or against the same target insect species. In order to delay the development of insect resistance to plants by using different proteins with different but different modes of action (eg binding to different receptor binding sites in insects) It contains a plurality of transgenes encoding any one protein from 1 to 8.
(遺伝子工学などの植物バイオテクノロジー法によって得た)本発明によりまた処理し得る植物又は植物品種は、非生物ストレスに対して耐性がある。形質転換によって、又はこのようなストレス耐性を与える突然変異を含有する植物の選択によって、このような植物を得ることができる。特に有用なストレス耐性植物には以下のものが含まれる:
a.植物細胞においてポリ(ADP−リボース)ポリメラーゼ(PARP)遺伝子の発現および/又は活性を低下させることができるトランス遺伝子を含有する植物又はWO00/04173又はEP04077984.5又はEP06009836.5に記載のような植物。
b.例えばWO2004/090140に記載のような、植物又は植物細胞のPARGコード遺伝子の発現および/又は活性を低下させることができるストレス耐性促進トランス遺伝子を含有する植物。
c.例えばEP04077624.7又はWO2006/133827又はPCT/EP07/002433に記載のような、ニコチンアミダーゼ、ニコチネートホスホリボシルトランスフェラーゼ、ニコチン酸モノヌクレオチドアデニルトランスフェラーゼ、ニコチンアミドアデニンジヌクレオチドシンテターゼ又はニコチンアミドホスホリボシルトランスフェラーゼを含む、ニコチンアミドアデニンジヌクレオチドサルベージ合成経路の、植物で機能的な酵素をコードするストレス耐性促進トランス遺伝子を含有する植物。
Plants or plant varieties that can also be treated according to the present invention (obtained by plant biotechnology methods such as genetic engineering) are resistant to abiotic stress. Such plants can be obtained by transformation or by selection of plants containing mutations that confer such stress tolerance. Particularly useful stress tolerant plants include:
a. Plants containing a transgene capable of reducing the expression and / or activity of the poly (ADP-ribose) polymerase (PARP) gene in plant cells or plants as described in WO00 / 04173 or EP040777984.5 or EP06009836.5 .
b. A plant containing a stress tolerance promoting transgene capable of reducing the expression and / or activity of a PARG-encoding gene in a plant or plant cell, as described in WO 2004/090140, for example.
c. Including nicotinamidase, nicotinate phosphoribosyltransferase, nicotinic acid mononucleotide adenyltransferase, nicotinamide adenine dinucleotide synthetase or nicotinamide phosphoribosyltransferase, as described for example in EP 04077624.7 or WO 2006/133828 or PCT / EP07 / 002433 A plant comprising a stress tolerance promoting transgene encoding a functional enzyme in a plant of the nicotinamide adenine dinucleotide salvage synthesis pathway.
(遺伝子工学などの植物バイオテクノロジー法によって得られる)本発明によりまた処理し得る植物又は植物品種は、収穫産物の量的、品質および/又は保存安定性の変化および/又は収穫産物の具体的な成分の特性の変化を示す:例えば、
1)改質デンプンを合成するトランスジェニック植物(その物理化学的性質、特にアミロース含量又はアミロース/アミロペクチン比、分枝の程度、平均鎖長、側鎖分布、粘性挙動、ゲル化強度、デンプン粒度および/又はデンプン粒子形態が、特殊応用に対してより適するように、野生型植物細胞又は植物での合成デンプンと比較して変化している。)。改質デンプンを合成する前記トランスジェニック植物は、例えば、EP0571427、WO95/04826、EP0719338、WO96/15248、WO96/19581、WO96/27674、WO97/11188、WO97/26362、WO97/32985、WO97/42328、WO97/44472、WO97/45545、WO98/27212、WO98/40503、WO99/58688、WO99/58690、WO99/58654、WO00/08184、WO00/08185、WO00/08175、WO00/28052、WO00/77229、WO01/12782、WO01/12826、WO02/101059、WO03/071860、WO2004/056999、WO2005/030942、WO2005/030941、WO2005/095632、WO2005/095617、WO2005/095619、WO2005/095618、WO2005/123927、WO2006/018319、WO2006/103107、WO2006/108702、WO2007/009823、WO00/22140、WO2006/063862、WO2006/072603、WO02/034923、EP06090134.5、EP06090228.5、EP06090227.7、EP07090007.1、EP07090009.7、WO01/14569、WO02/79410、WO03/33540、WO2004/078983、WO01/19975、WO95/26407、WO96/34968、WO98/20145、WO99/12950、WO99/66050、WO99/53072、US6734341、WO00/11192、WO98/22604、WO98/32326、WO01/98509、WO01/98509、WO2005/002359、US5824790、US6013861、WO94/04693、WO94/09144、WO94/11520、WO95/35026、WO97/20936で開示されている。
2)非デンプン炭水化物ポリマーを合成する又は野生型植物と比較して遺伝的改変なしで変更された特性を有する非デンプン炭水化物ポリマーを合成するトランスジェニック植物。例としては、EP0663956、WO96/01904、WO96/21023、WO98/39460およびWO99/24593で開示されるような(特にイヌリンおよびレバン型の)ポリフルクトースを産生する植物、WO95/31553、US2002031826、US6284479、US5712107、WO97/47806、WO97/47807、WO97/47808およびWO00/14249で開示されるようなα1,4グルカンを産生する植物、WO00/73422で開示されるようなα−1,6分枝α−1,4−グルカンを産生する植物、WO00/47727、EP06077301.7、US5908975およびEP0728213で開示されるようなアルテルナン(alternan)を産生する植物など。
3)例えばWO2006/032538、WO2007/039314、WO2007/039315、WO2007/039316、JP2006304779およびWO2005/012529で開示されるようなヒアルロナンを産生するトランスジェニック植物が挙げられる。
Plants or plant varieties that can also be treated according to the present invention (obtained by plant biotechnology methods such as genetic engineering) are the quantitative, quality and / or storage stability changes of the harvested product and / or the specifics of the harvested product. Indicates a change in the properties of an ingredient: for example
1) transgenic plants that synthesize modified starch (its physicochemical properties, in particular amylose content or amylose / amylopectin ratio, degree of branching, average chain length, side chain distribution, viscous behavior, gel strength, starch particle size and And / or starch particle morphology has changed compared to synthetic starch in wild type plant cells or plants to make it more suitable for special applications). The transgenic plants that synthesize modified starch are, for example, EP 0571427, WO95 / 04826, EP0719338, WO96 / 15248, WO96 / 19581, WO96 / 27274, WO97 / 11188, WO97 / 26362, WO97 / 32985, WO97 / 42328, WO97 / 44472, WO97 / 45545, WO98 / 27212, WO98 / 40503, WO99 / 58688, WO99 / 58690, WO99 / 58654, WO00 / 08184, WO00 / 08185, WO00 / 08175, WO00 / 28052, WO00 / 77229, WO01 / 12782, WO01 / 12826, WO02 / 101059, WO03 / 071860, WO2004 / 056999, WO2 05/030942, WO2005 / 030941, WO2005 / 095632, WO2005 / 095617, WO2005 / 095619, WO2005 / 095618, WO2005 / 123927, WO2006 / 018319, WO2006 / 103107, WO2006 / 108702, WO2007 / 009823, WO00 / 22140, WO00 / 22140 063862, WO2006 / 076023, WO02 / 034923, EP06090134.5, EP0609028.5, EP06090227.7, EP0707097.1, EP070900099.7, WO01 / 14569, WO02 / 79410, WO03 / 078983, WO01 / 079993, WO01 / 19975 WO95 / 264 7, WO96 / 34968, WO98 / 20145, WO99 / 12950, WO99 / 66050, WO99 / 53072, US67334341, WO00 / 11192, WO98 / 22604, WO98 / 32326, WO01 / 98509, WO01 / 98509, WO2005 / 002359, US5824790, US 6013861, WO 94/04693, WO 94/09144, WO 94/11520, WO 95/35026, WO 97/20936.
2) A transgenic plant that synthesizes a non-starch carbohydrate polymer or synthesizes a non-starch carbohydrate polymer with altered properties without genetic modification compared to a wild-type plant. Examples include plants producing polyfructose (especially inulin and levan type) such as disclosed in EP 0 663 356, WO 96/01904, WO 96/21023, WO 98/39460 and WO 99/24593, WO 95/31553, US2002031826, US6284479, Plants producing α1,4 glucan as disclosed in US 5712107, WO 97/47806, WO 97/47807, WO 97/47808 and WO 00/14249, α-1,6 branched α-as disclosed in WO 00/73422 Plants producing 1,4-glucan, producing alternans as disclosed in WO 00/47727, EP06077301.7, US 5908975 and EP 0728213 Such as plants.
3) Examples include transgenic plants that produce hyaluronan as disclosed in WO2006 / 032538, WO2007 / 039314, WO2007 / 039315, WO2007 / 039316, JP2006304779 and WO2005 / 012529.
本発明により処理し得る特に有用なトランスジェニック植物は、かかる請願が認可されているにせよ保留されているにせよ、アメリカ合衆国における農務省(USDA)のAnimal and Plant Health Inspection Service(APHIS)に対する非規制状態に対する請願対象である、形質転換事象又は形質転換事象の組み合わせを含有する植物である。この情報は、常時、APHIS(4700 River Road Riverdale、MD20737、USA)から、例えばそのインターネットサイト(URL http://www.aphis.usda.gov/brs/not__reg.html)において容易に入手可能である。 Particularly useful transgenic plants that can be treated according to the present invention are unregulated against the Department of Agriculture (USDA) Animal and Plant Health Inspection Service (APHIS) in the United States, whether such petition is granted or pending. A plant containing a transformation event or a combination of transformation events that is the subject of a petition for a condition. This information is always readily available from APHIS (4700 River Road Riverdale, MD 20737, USA), for example at its Internet site (URL http://www.aphis.usda.gov/brs/not_reg.html). .
1つの形質転換事象又は形質転換事象の組み合わせを含有するさらなる特に有用な植物は、例えば、様々な国又は地方の規制当局からのデータベースで列挙されている(例えば、http://gmoinfo.jrc.it/gmp_browse.aspxおよびhttp://www.agbios.com/dbase.phpを参照。)。 Additional particularly useful plants containing one transformation event or a combination of transformation events are listed, for example, in databases from various national or local regulatory authorities (see, for example, http: //gmoinfo.jrc. see it / gmp_browse.aspx and http://www.agbios.com/dbase.php).
さらに特に、トランスジェニック植物には、表Aで列挙する特許公開の何れかに記載のような農学的に中立であるか又は有益な位置にトランス遺伝子を含有する植物が含まれる。 More particularly, transgenic plants include plants that are agronomically neutral or contain the transgene in a beneficial position as described in any of the patent publications listed in Table A.
本発明の組み合わせ組成物は、水稲病害虫の防除のために使用するに際して、通常の製剤形態にすることができる。 When the combination composition of the present invention is used for controlling paddy rice pests, it can be converted into a usual preparation form.
製剤形態の例には、エアロゾルディスペンサー、カプセル懸濁液、冷噴霧濃縮剤、温噴霧濃縮剤、封入顆粒、細粒、種子処理用のフロアブル濃縮剤、調製済み溶液、粉剤、乳化濃厚剤(emulsifiable concentrate)、水中油乳剤、油中水乳剤、マクロ粒剤、微粒剤、油分散性粉末、油混和性フロアブル濃縮剤、油混和性液体、泡剤、ペースト、農薬被覆種子、懸濁剤(フロアブル剤)、懸濁液−乳液濃縮剤、可溶濃厚剤(soluble concentrate)、懸濁液、可溶粉剤(soluble powder)、顆粒、顆粒又は錠剤水和剤、種子処理用の水溶剤、水和剤、活性化合物を浸含させた天然および合成物質、ポリマー性物質中および種子用被覆物中のマイクロカプセル化ならびに、ULV−冷および温噴霧製剤、ガス(圧力下)、ガス発生製品、植物ロッドレット、乾燥種子処理用粉末、種子処理用の溶液、極小量(ULV)液、極小量(ULV)懸濁液、顆粒又は錠剤水和剤、スラリー処理用の粉末水和剤などが含まれ得る。 Examples of dosage forms include aerosol dispensers, capsule suspensions, cold spray concentrates, hot spray concentrates, encapsulated granules, fine granules, flowable concentrates for seed treatment, prepared solutions, powders, emulsifiable concentrates. concentrate), oil-in-water emulsion, water-in-oil emulsion, macro granule, fine granule, oil-dispersible powder, oil-miscible flowable concentrate, oil-miscible liquid, foam, paste, pesticide-coated seed, suspending agent (floorable) Agent), suspension-emulsion concentrate, soluble concentrate, suspension, soluble powder, granule, granule or tablet wettable powder, water solvent for seed treatment, hydration Agents, natural and synthetic materials impregnated with active compounds, microencapsulation in polymeric materials and seed coatings, and ULV-cooled Spray formulation, gas (under pressure), gas generating product, plant rodlet, dry seed treatment powder, seed treatment solution, ultra-low volume (ULV) liquid, ultra-low volume (ULV) suspension, granule or tablet Wettable powders, powdered wettable powders for slurry processing and the like may be included.
これらの製剤はそれ自体既知の方法によって調製することができる。例えば、前記の各有効成分を、固体又は液体の担体又は希釈剤、必要な場合には、界面活性剤、増量剤、農学的に許容可能な添加剤又はその他の製剤用補助剤と混合することによって、本発明に従う製剤を調製することができる。 These preparations can be prepared by methods known per se. For example, each of the above active ingredients is mixed with a solid or liquid carrier or diluent, if necessary, a surfactant, a bulking agent, an agriculturally acceptable additive or other formulation adjuvant. The preparation according to the invention can be prepared by:
本発明の組成物の製剤化に際して用い得る固体担体および/又は固体希釈剤としては、鉱石を原料とする無機物質(例えば、クレー、カオリン、タルク、炭酸カルシウム、珪藻土、ゼオライト、ベントナイト、酸性白土、活性白土、アタパルガスクレー、モンモリロナイト、バーミキューライト、パーライト、軽石、硅砂、硅石、方解石、大理石、海泡石、白雲石)および無機および有機粉末の合成顆粒など;
合成品(ホワイトカーボン、例えば、親水性シリカ、疎水性シリカおよびケイ酸カルシウム、酸化アルミニウム、合成ゼオライト、二酸化チタンなど);
大豆粉、タバコ粉、トウモロコシ穂軸粉、クルミ粉、小麦粉、木粉、でんぷん、結晶セルロース、紙、おがくず、ココやしの実のから、トウモロコシ穂軸およびタバコ茎などの植物性有機物質;
クマロン樹脂、石油樹脂、アルキッド樹脂、ポリアルキレングリコール、ケトン樹脂、エステルガム等の合成又は天然の高分子化合物;
カルナバロウ、蜜ロウ等のワックス類;
尿素、乳糖、ショ糖、硫酸アンモニウム、塩化カリウム等の水溶性物質が例示できる。
Examples of the solid carrier and / or solid diluent that can be used in the formulation of the composition of the present invention include inorganic materials based on ore (for example, clay, kaolin, talc, calcium carbonate, diatomaceous earth, zeolite, bentonite, acidic clay, Active clays, attapulgous clay, montmorillonite, vermiculite, perlite, pumice, cinnabar, aragonite, calcite, marble, cuffstone, dolomite) and synthetic granules of inorganic and organic powders;
Synthetic products (white carbon, such as hydrophilic silica, hydrophobic silica and calcium silicate, aluminum oxide, synthetic zeolite, titanium dioxide, etc.);
Plant organic matter such as corn cob and tobacco stem from soy flour, tobacco powder, corn cob flour, walnut flour, wheat flour, wood flour, starch, crystalline cellulose, paper, sawdust, coconuts;
Synthetic or natural polymer compounds such as coumarone resin, petroleum resin, alkyd resin, polyalkylene glycol, ketone resin, ester gum;
Waxes such as carnauba wax and beeswax;
Water-soluble substances such as urea, lactose, sucrose, ammonium sulfate and potassium chloride can be exemplified.
適当な液体担体および/又は液体希釈剤としては、例えば、ヤシ油、菜種油、コーン油、大豆油、米ぬか油等の油脂類;
ケロシン、鉱油、スピンドル油、ホワイトオイル、ノルマルパラフィン、イソパラフィン、ナフテン等のパラフィン系もしくはナフテン系炭化水素系溶剤;
キシレン、アルキルベンゼン、アルキルナフタレン等の芳香族炭化水素系溶剤;
エタノール、ベンジルアルコール、イソプロパノール、シクロヘキサノール等のアルコール類;
エチレングリコール、ジエチレングリコール、プロピレングリコール、ポリエチレングリコール等の多価アルコール類;
エチレングリコールエチルエーテル、エチレングリコールフェニルエーテル、ジエチレングリコールエチルエーテル、ジエチレングリコールブチルエーテル等のエーテルアルコール類;
メチルエチルケトン、ジイソブチルケトン、シクロヘキサノン、アセトフェノン、イソホロン、γ−ブチロラクトン等のケトン類;
ヤシ油脂肪酸メチルエステル等の脂肪酸メチルエステル、コハク酸ジメチルエステル、グリタミン酸ジメチルエステルやアジピン酸ジメチルエステル等の二塩基酸メチルエステル、酢酸エチル、酢酸アミル、エチレングリコールアセテート、ジエチレングリコールアセテート等のエステル類;
ジオキサン、テトラヒドロフラン等のエーテル類;
ジメチルホルムアミド、ジメチルアセトアミド、ジメチルスルホキシド、N−アルキルピロリドン等の極性溶媒あるいは水等が例示できる。
Suitable liquid carriers and / or liquid diluents include, for example, oils and fats such as coconut oil, rapeseed oil, corn oil, soybean oil, rice bran oil;
Paraffinic or naphthenic hydrocarbon solvents such as kerosene, mineral oil, spindle oil, white oil, normal paraffin, isoparaffin, naphthene;
Aromatic hydrocarbon solvents such as xylene, alkylbenzene, alkylnaphthalene;
Alcohols such as ethanol, benzyl alcohol, isopropanol, cyclohexanol;
Polyhydric alcohols such as ethylene glycol, diethylene glycol, propylene glycol, polyethylene glycol;
Ether alcohols such as ethylene glycol ethyl ether, ethylene glycol phenyl ether, diethylene glycol ethyl ether, diethylene glycol butyl ether;
Ketones such as methyl ethyl ketone, diisobutyl ketone, cyclohexanone, acetophenone, isophorone, γ-butyrolactone;
Fatty acid methyl esters such as coconut oil fatty acid methyl ester, dimethyl succinate, dibasic acid methyl ester such as dimethyl glutamate and dimethyl adipate, esters such as ethyl acetate, amyl acetate, ethylene glycol acetate, diethylene glycol acetate;
Ethers such as dioxane and tetrahydrofuran;
Examples include polar solvents such as dimethylformamide, dimethylacetamide, dimethylsulfoxide, N-alkylpyrrolidone, water, and the like.
その他に有効成分の乳化、分散、湿潤、拡展、分解防止、効力増強等の目的および/又は製剤物性の改良(崩壊性調節、流動性改善、凍結防止、耐雨性付与等)の目的で、界面活性剤、結合剤およびその他の補助剤を使用することができる。使用し得る界面活性剤としては、非イオン性、陰イオン性、陽イオン性および両性イオン性のいずれのタイプの化合物でも使用し得るが、通常は非イオン性および/又は陰イオン性の化合物が使用される。適当な非イオン性界面活性剤としては、例えば、ソルビタン脂肪酸エステル、ポリオキシアルキレンソルビタン脂肪酸エステル、ショ糖脂肪酸エステル;ポリオキシアルキレン脂肪酸エステル、ポリオキシアルキレン樹脂酸エステル、ポリオキシアルキレン脂肪酸ジエステル;ポリオキシアルキレンひまし油、ポリオキシアルキレン硬化ひまし油;ポリオキシアルキレンアルキルエーテル;ポリオキシアルキレンアルキルフェニルエーテル、ポリオキシアルキレンジアルキルフェニルエーテル、ポリオキシアルキレンアルキルフェニルエーテルホルマリン縮合物;ポリオキシエチレン・ポリオキシプロピレンブロックポリマー、アルキルポリオキシエチレン・ポリオキシプロピレンブロックポリマーエーテル、アルキルフェニルポリオキシエチレン・ポリオキシプロピレンブロックポリマーエーテル;ポリオキシアルキレンアルキルアミン、ポリオキシアルキレン脂肪酸アミド;ポリオキシアルキレンベンジルフェニル(又はフェニルフェニル)エーテル、ポリオキシアルキレンスチリルフェニル(又はフェニルフェニル)エーテル;ポリオキシアルキレンエーテルおよびエステル型シリコンおよびフッ素系界面活性剤等を挙げることができる。 In addition, for the purpose of emulsifying, dispersing, wetting, spreading, preventing decomposition, enhancing efficacy and / or improving the physical properties of the formulation (disintegration control, fluidity improvement, freezing prevention, provision of rain resistance, etc.) Surfactants, binders and other adjuvants can be used. As the surfactant that can be used, any type of nonionic, anionic, cationic and zwitterionic compounds can be used, but usually nonionic and / or anionic compounds are used. used. Suitable nonionic surfactants include, for example, sorbitan fatty acid esters, polyoxyalkylene sorbitan fatty acid esters, sucrose fatty acid esters; polyoxyalkylene fatty acid esters, polyoxyalkylene resin acid esters, polyoxyalkylene fatty acid diesters; polyoxy Alkylene castor oil, polyoxyalkylene hydrogenated castor oil; polyoxyalkylene alkyl ether; polyoxyalkylene alkyl phenyl ether, polyoxyalkylene dialkyl phenyl ether, polyoxyalkylene alkyl phenyl ether formalin condensate; polyoxyethylene / polyoxypropylene block polymer, alkyl Polyoxyethylene / polyoxypropylene block polymer ether, alkylphenyl polyoxye Polyoxyalkylene alkylamine, polyoxyalkylene fatty acid amide; polyoxyalkylene benzylphenyl (or phenylphenyl) ether, polyoxyalkylene styrylphenyl (or phenylphenyl) ether; polyoxyalkylene ether and Examples include ester type silicon and fluorine-based surfactants.
また、適当な陰イオン性界面活性剤としては、例えば、アルキルサルフェート塩、ポリオキシアルキレンアルキルエーテルサルフェート塩、ポリオキシアルキレンアルキルフェニルエーテルサルフェート塩、ポリオキシアルキレンベンジル(又はスチリル)フェニル(又はフェニルフェニル)エーテルサルフェート塩、ポリオキシエチレン・ポリオキシプロピレンブロックポリマーサルフェート塩;パラフィン(アルカン)スルホネート塩、アルファオレフィンスルホネート塩、ジアルキルスルホサクシネート塩、アルキルベンゼンスルホネート塩、モノ又はジアルキルナフタレンスルホネート塩、ナフタレンスルホネート・ホルマリン縮合物塩、アルキルジフェニルエーテルジスルホネート塩、リグニンスルホネート塩、ポリオキシアルキレンアルキルフェニルエーテルスルホネート塩、ポリオキシアルキレンエーテルスルホコハク酸ハーフエステル塩;脂肪酸塩、Nメチル脂肪酸サルコシネート、樹脂酸塩;ポリオキシアルキレンアルキルエーテルホスフェート塩、ポリオキシアルキレンモノ又はジアルキルフェニルエーテルホスフェート塩、ポリオキシアルキレンベンジル(又はスチリル)化フェニル(又はフェニルフェニル)エーテルホスフェート塩、ポリオキシエチレン・ポリオキシプロピレンブロックポリマーホスフェート塩;ポリアクリル酸塩、ポリカルボン酸塩等を挙げることができる。 Suitable anionic surfactants include, for example, alkyl sulfate salts, polyoxyalkylene alkyl ether sulfate salts, polyoxyalkylene alkyl phenyl ether sulfate salts, polyoxyalkylene benzyl (or styryl) phenyl (or phenylphenyl). Ether sulfate salt, polyoxyethylene / polyoxypropylene block polymer sulfate salt; paraffin (alkane) sulfonate salt, alpha olefin sulfonate salt, dialkyl sulfosuccinate salt, alkylbenzene sulfonate salt, mono or dialkyl naphthalene sulfonate salt, naphthalene sulfonate / formalin condensation Salt, alkyl diphenyl ether disulfonate, lignin sulfonate, polyoxyalkyl Alkyl phenyl ether sulfonate salt, polyoxyalkylene ether sulfosuccinic acid half ester salt; fatty acid salt, N-methyl fatty acid sarcosinate, resin acid salt; polyoxyalkylene alkyl ether phosphate salt, polyoxyalkylene mono- or dialkyl phenyl ether phosphate salt, polyoxy Examples thereof include alkylene benzyl (or styryl) phenyl (or phenylphenyl) ether phosphate salt, polyoxyethylene / polyoxypropylene block polymer phosphate salt; polyacrylate, polycarboxylate and the like.
陽イオン性界面活性剤としてはアルキルトリメチルアンモニウムクロライド、メチル・ポリオキシエチレン・アルキルアンモニウムクロライド、アルキル・Nメチルピリジニウムブロマイド、モノ又はジアルキルメチル化アンモニウムクロライド、アルキルペンタメチルプロピレンジアミンジクロライド等のアンモニウム型;アルキルジメチルベンザルコニウムクロライド、ベンゼトニウムクロライド等のベンザルコニウム型を挙げることができる。 Cationic surfactants include alkyl trimethyl ammonium chloride, methyl polyoxyethylene alkyl alkyl ammonium chloride, alkyl N-methyl pyridinium bromide, mono- or dialkyl methylated ammonium chloride, alkyl pentamethylpropylenediamine dichloride, and other ammonium types; alkyl Examples thereof include benzalkonium types such as dimethylbenzalkonium chloride and benzethonium chloride.
両イオン性界面活性剤としてはジアルキルジアミノエチルベタイン、アルキルジメチルベンジルベタイン等のベタイン型を挙げることができる。 Examples of amphoteric surfactants include betaine types such as dialkyldiaminoethylbetaine and alkyldimethylbenzylbetaine.
また、結合剤としてはベントナイト、カゼイン、ゼラチン、デンプン、デキストリン、リグニンスルホン酸塩、アルギン酸塩、アラビアゴム、キサンタンガム、カルボキシメチルセルロース、メチルセルロース、ポリビニルアルコール、ポリビニルピロリドン、天然リン脂質(例えばセファリンおよびレシチン)および合成リン脂質等を挙げることができる。 As binders, bentonite, casein, gelatin, starch, dextrin, lignin sulfonate, alginate, gum arabic, xanthan gum, carboxymethyl cellulose, methyl cellulose, polyvinyl alcohol, polyvinyl pyrrolidone, natural phospholipids (for example, cephalin and lecithin) and Examples thereof include synthetic phospholipids.
その他の補助剤として、崩壊性調製剤、凍結防止剤、防腐剤、流動性改良材、消泡剤、保湿剤、拡展剤、耐雨性付与剤、着色剤等を挙げることができる。 Examples of other adjuvants include disintegrating preparation agents, antifreezing agents, preservatives, fluidity improvers, antifoaming agents, moisturizing agents, spreading agents, rain resistance imparting agents, and coloring agents.
上記の担体および界面活性剤、結合剤や種々の補助剤は、製剤の剤型、適用場面等を考慮して、目的に応じてそれぞれ単独で又は組み合わせて適宜使用することができる。 The above carriers, surfactants, binders and various adjuvants can be appropriately used alone or in combination depending on the purpose in consideration of the dosage form of the preparation, application scenes, and the like.
製剤は、一般に、各有効成分の合計で0.1〜95重量%、好ましくは0.5〜90重量%の濃度で含有することができる。 In general, the preparation can be contained at a concentration of 0.1 to 95% by weight, preferably 0.5 to 90% by weight in total of each active ingredient.
本発明の組み合わせ組成物は、使用に際して、そのまま又はその様々な製剤の形態で、例えば、1つの「調合済み」形態で、1つの活性化合物の個別の製剤から構成される組み合わせ噴霧混合物で(使用時の「タンク混合」など)、および連続して施用する場合1つの活性成分の組み合わせ使用で(即ち、適度に短期間(数時間又は数日)で逐次に)、使用することができる。好ましくは、化合物(a)および(b)および/又は(c)を施用する順序は本発明を実施するのに必須ではない。 The combination compositions of the present invention, in use, are used as such or in the form of their various formulations, for example in a combined spray mixture consisting of individual formulations of one active compound, in one “prepared” form. Such as “tank mixing” at the time), and when applied continuously, can be used in combination with a single active ingredient (ie, sequentially in a reasonably short period (hours or days)). Preferably, the order in which compounds (a) and (b) and / or (c) are applied is not essential for practicing the present invention.
実施例
試験例1:水稲苗の強度および生育試験
方法
水稲用標準育苗箱(30cm x 60cm x 3cm)に育苗用人口培土を約2.5l敷き詰め、催芽した種籾(品種・コシヒカリ)を播種した。潅水後、直ちに所定濃度になるように予め調製された各有効成分の粒状物を箱あたり50g均一に散粒し、育苗用人工培土1lにより覆土した。その後、育苗箱を加温出芽器に入れ、約30度で2日間保持した。出芽後、育苗用ビニールハウスに移動し、継続的に苗の生育程度を肉眼観察した。播種3週間後(移植適期)に、茎葉部および根部(いわゆるマット形成程度、特に箱底面、側面の発根量)を肉眼観察した。更に、箱苗の一部(10cm x 10cm)を切り出し、この苗片の破断限界値を測定することで箱苗の強度を評価した。即ち、苗片の一方を固定し、もう一方をメカニカルフォースゲージを用い箱苗を徐々に引っ張り、苗片が破断した時の値 を破断限界値(=引張強度)として測定した。肉眼観察による評価は3反復の平均値、破断限界値測定用苗片(10cm x 10cm)は、各反復2ケ所ずつ合計6片を測定した平均の結果を第1表に示した
肉眼観察の評価基準:
1=健全
2=極軽微な根の生育遅延がみられる
3=軽微な根の生育遅延がみられるが実用上問題なし
4=実用上やや問題となる根の生育遅延
5=実用上問題となる根の生育遅延
箱苗強度の評価基準:
無処理区におけるメカニカルフォースゲージによる引っ張り強度の平均値を100として、
1=95以上
2=90以上95未満
3=70以上90未満
4=50以上70未満
5=50未満
Examples Test example 1: Strength and growth test of paddy rice seedling Method About 2.5 liters of artificial soil for seedling seedling was spread in a standard seedling box for paddy rice (30 cm x 60 cm x 3 cm), and the sprouting seed pod (cultivar Koshihikari) was sown. Immediately after irrigation, 50 g of each active ingredient granular material prepared in advance so as to have a predetermined concentration was uniformly dispersed per box and covered with 1 l of artificial soil for raising seedlings. Thereafter, the seedling box was placed in a warm germination device and held at about 30 degrees for 2 days. After emergence, the seedlings were transferred to a nursery greenhouse, and the degree of seedling growth was continuously observed with the naked eye. Three weeks after sowing (suitable time for transplantation), the foliage and roots (so-called mat formation degree, especially the amount of rooting on the bottom of the box and the side) were visually observed. Further, a portion (10 cm × 10 cm) of the box seedling was cut out, and the strength of the box seedling was evaluated by measuring the breaking limit value of the seedling. That is, one of the seedlings was fixed, and the other seedling was gradually pulled by using a mechanical force gauge, and the value when the seedling broke was measured as the breaking limit value (= tensile strength). Evaluation by macroscopic observation is the average value of 3 repetitions, and the seeds for fracture limit value measurement (10 cm x 10 cm) are shown in Table 1 for the average results of measuring 6 pieces in total at 2 repetitions. Evaluation of visual observation Standard:
1 = Healthy 2 = Slightly delayed root growth 3 = Slightly delayed root growth but no practical problem 4 = Slightly problematic root growth 5 = Practical problem Root growth delay Evaluation criteria for box seedling strength:
Assuming that the average value of tensile strength by mechanical force gauge in the untreated section is 100,
1 = 95 or more 2 = 90 or more and less than 95 3 = 70 or more and less than 90 4 = 50 or more and less than 70 5 = less than 50
試験例2
イネツトムシに対する防除効果試験
方法
水稲用標準育苗箱で栽培した移植適期のイネ(品種コシヒカリ)にイソチアニル2%(w/w)とフィプロニル1%(w/w)を含む粒剤組成物を箱あたり50g散布し、軽く潅水後直ちに田植え機を用いて移植した。現地の慣行に従って栽培管理し、移植70日後に各区600株について被害株数を計数した。
Test example 2
Test for control effect on rice beetles Method 50g of a granule composition containing 2% (w / w) isothianyl and 1% fipronil (w / w) in rice (variety Koshihikari) in a suitable time for transplantation cultivated in a standard nursery box for paddy rice After spraying, lightly irrigated and immediately transplanted using a rice planter. Cultivation management was carried out according to local practice, and the number of damaged strains was counted for 600 strains in each ward 70 days after transplantation.
結果を第2表に示す。 The results are shown in Table 2.
試験例3
イネいもち病に対する防除効果試験
方法
水稲用標準育苗箱で栽培した移植適期のイネ(品種ひとめぼれ)に試験例2と同様の粒剤組成物を箱あたり50g散布し、軽く潅水後直ちに田植え機を用いて移植した。現地の慣行に従って栽培管理し、移植72日後に各区120株について病斑面積率を調査した。結果を第3表に示す。
Test example 3
Test method for controlling rice blast disease Method 50g of the same granule composition as in Test Example 2 is sprayed on rice (variety Hitomebore) suitable for transplantation cultivated in a standard rice seedling box for paddy rice. And transplanted. Cultivation management was carried out according to local practices, and the lesion area rate was examined for 120 strains in each ward 72 days after transplantation. The results are shown in Table 3.
製剤例1(微粒剤)
0.2−0.7mmの粒度分布を有する粘土鉱物粒85.5重量部を容器回転型混合機に入れ、回転下に液体希釈剤10重量部とともにイソチアニル2重量部、フィプロニル1重量部を噴霧し、ホワイトカーボン1.5重量部を加え、微粒剤とする。
Formulation Example 1 (fine granules)
Put 85.5 parts by weight of clay mineral particles having a particle size distribution of 0.2-0.7 mm in a rotating container mixer, and spray 10 parts by weight of liquid diluent and 2 parts by weight of isotianil and 1 part by weight of fipronil under rotation. Then, 1.5 parts by weight of white carbon is added to make a fine granule.
製剤例2(微粒剤)
0.2−0.7mmの粒度分布を有する粘土鉱物粒84.5重量部を容器回転型混合機に入れ、回転下に液体希釈剤10重量部とともにイソチアニル2重量部、フィプロニル1重量部、イミダクロプリド1重量部を噴霧し、ホワイトカーボン1.5重量部を加え、微粒剤とする。
Formulation Example 2 (fine granules)
84.5 parts by weight of clay mineral particles having a particle size distribution of 0.2-0.7 mm are placed in a rotating container mixer. Under rotation, 10 parts by weight of liquid diluent and 2 parts by weight of isothianyl, 1 part by weight of fipronil, imidacloprid 1 part by weight is sprayed and 1.5 parts by weight of white carbon is added to form a fine granule.
製剤例3(顆粒状水和剤)
イソチアニル30重量部、フィプロニル15重量部、リグニンスルホン酸ナトリウム塩15重量部、ナトリウムベントナイト(モンモリロナイト)15重量部、焼成珪藻土粉末15重量部およびタルク10重量部を充分に混合し、これにポリオキシアルキレントリスチリルフェニルエーテル硫酸ナトリウム塩5重量部を含む水を加えて混練した後、0.5mmのスクリーンを装着した押し出し式造粒機で押出し、乾燥して顆粒状水和剤とする。
Formulation Example 3 (granular wettable powder)
30 parts by weight of isotianil, 15 parts by weight of fipronil, 15 parts by weight of sodium lignin sulfonate, 15 parts by weight of sodium bentonite (montmorillonite), 15 parts by weight of calcined diatomaceous earth powder and 10 parts by weight of talc are mixed thoroughly, and this is polyoxyalkylene After adding and kneading water containing 5 parts by weight of tristyrylphenyl ether sulfate sodium salt, the mixture is extruded with an extrusion granulator equipped with a 0.5 mm screen and dried to obtain a granular wettable powder.
Claims (12)
(b)フィプロニル又はエチプロールを組み合わせて含んでなる殺菌殺虫組成物。 (A) 3,4-dichloro-N- (2-cyanophenyl) isothiazole-5-carboxamide;
(B) A bactericidal insecticidal composition comprising a combination of fipronil or etiprol.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009532705A JP5346810B2 (en) | 2006-10-19 | 2007-10-06 | Bactericidal insecticidal composition |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006284626A JP2008100946A (en) | 2006-10-19 | 2006-10-19 | Fungicidal and insecticidal composition |
JP2006284626 | 2006-10-19 | ||
PCT/EP2007/008688 WO2008046533A2 (en) | 2006-10-19 | 2007-10-06 | Fungicidal and insecticidal composition |
JP2009532705A JP5346810B2 (en) | 2006-10-19 | 2007-10-06 | Bactericidal insecticidal composition |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010506866A true JP2010506866A (en) | 2010-03-04 |
JP5346810B2 JP5346810B2 (en) | 2013-11-20 |
Family
ID=38752458
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006284626A Pending JP2008100946A (en) | 2006-10-19 | 2006-10-19 | Fungicidal and insecticidal composition |
JP2009532705A Active JP5346810B2 (en) | 2006-10-19 | 2007-10-06 | Bactericidal insecticidal composition |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006284626A Pending JP2008100946A (en) | 2006-10-19 | 2006-10-19 | Fungicidal and insecticidal composition |
Country Status (6)
Country | Link |
---|---|
JP (2) | JP2008100946A (en) |
KR (1) | KR101466688B1 (en) |
CN (1) | CN101528040B (en) |
MY (1) | MY151597A (en) |
TW (1) | TWI448246B (en) |
WO (1) | WO2008046533A2 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011506357A (en) * | 2007-12-11 | 2011-03-03 | バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト | Use of active ingredient combinations to control animal parasites |
JP2011506359A (en) * | 2007-12-11 | 2011-03-03 | バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト | Active compound combinations |
WO2012153861A1 (en) * | 2011-05-10 | 2012-11-15 | Sumitomo Chemical Company, Limited | Method for promoting plant growth |
WO2012153860A1 (en) | 2011-05-10 | 2012-11-15 | Sumitomo Chemical Company, Limited | Method for promoting plant growth |
JP2016531892A (en) * | 2013-10-04 | 2016-10-13 | エフ エム シー コーポレーションFmc Corporation | How to improve plant growth |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106106497B (en) * | 2007-07-27 | 2022-02-22 | 拜耳知识产权有限责任公司 | Ternary active compound combinations |
CN101480185B (en) * | 2009-01-05 | 2012-01-25 | 深圳诺普信农化股份有限公司 | Pesticide composition with synergistic insecticidal action and use thereof |
JP6027442B2 (en) | 2009-10-15 | 2016-11-16 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | Active compound combinations |
JP5782678B2 (en) | 2010-04-27 | 2015-09-24 | 住友化学株式会社 | Pest control composition and use thereof |
UA109900C2 (en) | 2010-04-27 | 2015-10-26 | PESTICIDIC COMPOSITION AND ITS APPLICATIONS | |
NZ603839A (en) | 2010-04-27 | 2014-12-24 | Sumitomo Chemical Co | Pesticidal composition and its use |
JP5712504B2 (en) | 2010-04-27 | 2015-05-07 | 住友化学株式会社 | Pest control composition and use thereof |
UA107591C2 (en) | 2010-04-27 | 2015-01-26 | PESTICIDIC COMPOSITION AND ITS APPLICATIONS | |
WO2011135833A1 (en) | 2010-04-28 | 2011-11-03 | Sumitomo Chemical Company, Limited | Plant disease control composition and its use |
CN102858170B (en) | 2010-04-28 | 2014-12-10 | 住友化学株式会社 | Pesticidal composition and its use |
JP5789918B2 (en) | 2010-04-28 | 2015-10-07 | 住友化学株式会社 | Plant disease control composition and use thereof |
BR112012027385B1 (en) | 2010-04-28 | 2018-07-31 | Sumitomo Chemical Company, Limited | Plant disease control composition comprising carboxamide and QoI compounds as well as method for controlling plant disease |
JP5724212B2 (en) | 2010-04-28 | 2015-05-27 | 住友化学株式会社 | Plant disease control composition and use thereof |
JP5724211B2 (en) | 2010-04-28 | 2015-05-27 | 住友化学株式会社 | Plant disease control composition and use thereof |
JP5724210B2 (en) | 2010-04-28 | 2015-05-27 | 住友化学株式会社 | Plant disease control composition and use thereof |
JP2014088322A (en) * | 2011-01-12 | 2014-05-15 | Nippon Nohyaku Co Ltd | Plant growth regulator and use method thereof |
JP5834454B2 (en) * | 2011-04-08 | 2015-12-24 | 住友化学株式会社 | Rice cultivation method and rice seed germination promotion method |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001522840A (en) * | 1997-11-12 | 2001-11-20 | バイエル・アクチエンゲゼルシヤフト | Isothiazolecarboxamides and their application to protect plants |
JP2006528148A (en) * | 2003-07-23 | 2006-12-14 | バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト | Bactericidal active compound combination |
JP2006528149A (en) * | 2003-07-23 | 2006-12-14 | バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト | Disinfectant combination |
JP2007161603A (en) * | 2005-12-09 | 2007-06-28 | Bayer Cropscience Kk | Pest-controlling agent for paddy field |
-
2006
- 2006-10-19 JP JP2006284626A patent/JP2008100946A/en active Pending
-
2007
- 2007-10-06 JP JP2009532705A patent/JP5346810B2/en active Active
- 2007-10-06 MY MYPI20091395 patent/MY151597A/en unknown
- 2007-10-06 CN CN2007800387864A patent/CN101528040B/en active Active
- 2007-10-06 KR KR1020097007220A patent/KR101466688B1/en active IP Right Grant
- 2007-10-06 WO PCT/EP2007/008688 patent/WO2008046533A2/en active Application Filing
- 2007-10-18 TW TW096138947A patent/TWI448246B/en active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001522840A (en) * | 1997-11-12 | 2001-11-20 | バイエル・アクチエンゲゼルシヤフト | Isothiazolecarboxamides and their application to protect plants |
JP2006528148A (en) * | 2003-07-23 | 2006-12-14 | バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト | Bactericidal active compound combination |
JP2006528149A (en) * | 2003-07-23 | 2006-12-14 | バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト | Disinfectant combination |
JP2007161603A (en) * | 2005-12-09 | 2007-06-28 | Bayer Cropscience Kk | Pest-controlling agent for paddy field |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011506357A (en) * | 2007-12-11 | 2011-03-03 | バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト | Use of active ingredient combinations to control animal parasites |
JP2011506359A (en) * | 2007-12-11 | 2011-03-03 | バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト | Active compound combinations |
WO2012153861A1 (en) * | 2011-05-10 | 2012-11-15 | Sumitomo Chemical Company, Limited | Method for promoting plant growth |
WO2012153860A1 (en) | 2011-05-10 | 2012-11-15 | Sumitomo Chemical Company, Limited | Method for promoting plant growth |
US9119396B2 (en) | 2011-05-10 | 2015-09-01 | Sumitomo Chemical Company, Limited | Method for promoting plant growth |
US9232792B2 (en) | 2011-05-10 | 2016-01-12 | Sumitomo Chemical Company, Limited | Method for promoting plant growth |
JP2016531892A (en) * | 2013-10-04 | 2016-10-13 | エフ エム シー コーポレーションFmc Corporation | How to improve plant growth |
JP2019172683A (en) * | 2013-10-04 | 2019-10-10 | エフ エム シー コーポレーションFmc Corporation | Methods for improving plant growth |
Also Published As
Publication number | Publication date |
---|---|
TWI448246B (en) | 2014-08-11 |
WO2008046533A2 (en) | 2008-04-24 |
WO2008046533A3 (en) | 2009-01-22 |
MY151597A (en) | 2014-06-13 |
CN101528040A (en) | 2009-09-09 |
KR101466688B1 (en) | 2014-11-28 |
CN101528040B (en) | 2013-01-02 |
JP2008100946A (en) | 2008-05-01 |
KR20090066290A (en) | 2009-06-23 |
TW200833250A (en) | 2008-08-16 |
JP5346810B2 (en) | 2013-11-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5346810B2 (en) | Bactericidal insecticidal composition | |
US9877482B2 (en) | Use of succinate dehydrogenase inhibitors for controlling Sclerotinia ssp | |
KR101904054B1 (en) | Method for improving plant quality | |
EA022245B1 (en) | Pesticidal mixtures | |
EA017006B1 (en) | Pesticidal composition comprising fenamidone and an insecticide compound | |
EA030055B1 (en) | Active compound combinations comprising a (thio)carboxamide derivative and a fungicidal compound | |
EA021261B1 (en) | Pesticidal composition comprising fluopicolide and an insecticide compound | |
EA020281B1 (en) | Pesticidal mixtures | |
EA025427B1 (en) | Pesticidal mixtures | |
EA023113B1 (en) | Use of agrochemical mixtures for increasing the health of a plant | |
EA013402B1 (en) | Methods for reducing nematode damage | |
EA023771B1 (en) | Active compound combinations comprising a (thio)carboxamide derivative and an insecticidal or acaricidal or nematicidal active compound | |
EA029048B1 (en) | Active compounds combination comprising a lipo-chitooligosaccharide derivative for stimulating plant growth | |
EA024816B1 (en) | Method of controlling parasitic weeds with mixtures comprising herbicidal acetolactate synthase inhibitors and plant growth regulators | |
EA032177B1 (en) | Active compound combinations comprising a (thio)carboxamide derivative and fungicidal compounds | |
EA030236B1 (en) | Ternary fungicidal and pesticidal mixtures | |
JP5443396B2 (en) | Diflufenican-containing herbicide combinations | |
JP2011513256A (en) | Diflufenican-containing herbicide combinations | |
RU2755433C2 (en) | Use of insecticides to combat wireworms | |
JP5467059B2 (en) | Diflufenican-containing herbicide combinations | |
CN108024536A (en) | Succinate dehydrogenase inhibitors fluopyram is used for the purposes for preventing the balck shank in Cruciferae species | |
CN103562158B (en) | The method for improving plant quality | |
EP3183966B1 (en) | Method of controlling growth of als-tolerant plants | |
JP2017501216A (en) | Herbicides containing aclonifen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20101005 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20120918 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20120925 |
|
RD02 | Notification of acceptance of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7422 Effective date: 20121105 |
|
RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20121207 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20121220 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20121228 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130123 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130423 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130523 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20130806 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20130819 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5346810 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
R360 | Written notification for declining of transfer of rights |
Free format text: JAPANESE INTERMEDIATE CODE: R360 |
|
R370 | Written measure of declining of transfer procedure |
Free format text: JAPANESE INTERMEDIATE CODE: R370 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |