JP2009250782A - Embedding tray for preparing pathological tissue testing specimen - Google Patents

Embedding tray for preparing pathological tissue testing specimen Download PDF

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JP2009250782A
JP2009250782A JP2008098962A JP2008098962A JP2009250782A JP 2009250782 A JP2009250782 A JP 2009250782A JP 2008098962 A JP2008098962 A JP 2008098962A JP 2008098962 A JP2008098962 A JP 2008098962A JP 2009250782 A JP2009250782 A JP 2009250782A
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paraffin
embedding tray
cassette
locking
preparing
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JP5030841B2 (en
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Takuya Murakado
卓也 村角
Hidehiko Murakado
英彦 村角
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Murazumi Industrial Co Ltd
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Murazumi Industrial Co Ltd
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Abstract

<P>PROBLEM TO BE SOLVED: To provide an embedding tray for preventing the peeling of paraffin in the slice of a specimen from a cassette by discharging air stagnated in a paraffin housing part to improve the adhesiveness of paraffin to the base of a cassette body. <P>SOLUTION: The embedding tray 1 for preparing a pathological tissue testing specimen includes the paraffin housing part 2 composed of a bottom part 3 and the sidewall 4 vertically provided in the periphery of the bottom part 3, the cassette support part 5 provided to the upper outside of the housing part 2, and the locking walls 7 of three sides and the locking pawl 6 of one side both of which are vertically provided in the upper outside of the support part 5 and characterized in that grasping parts 9 are provided so as to be extended outward from the upper ends of the locking walls 7 opposed to each other among three locking walls 7 and air venting notch parts 8 are provided in the corner parts of the locking walls 7. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

本発明は病理組織検査標本作成用の包埋トレイに関し、更に詳しくは、パラフィン収容部内に滞留する空気を排出して、カセット本体の底面に対するパラフィンの付着性を良くし、検体が内包されたパラフィンをスライスして顕微鏡標本を作製する際にパラフィンがカセットから剥離するのを防止できる病理組織検査標本作成用の包埋トレイに関する。   The present invention relates to an embedding tray for preparing a histopathological specimen, and more specifically, discharges air staying in a paraffin container to improve the adherence of paraffin to the bottom surface of a cassette body, and paraffin in which a specimen is included. The present invention relates to an embedding tray for preparing a histopathological specimen that can prevent paraffin from peeling off from a cassette when a microscope specimen is sliced.

従来、この種の病理組織検査標本作成用の包埋トレイとしては、図１５に示したようなものが多用されている。この包埋トレイＴはパラフィン収容部Ｔ１と、その周縁に水平状に設けられたカセットを載置するためのカセット支承部Ｔ２と、その周縁に立設されたカセットの動きを止めるためのカセット係止壁Ｔ３と、その周縁に水平状に設けられた額縁部Ｔ４となり、更に、長手方向の額縁部Ｔ４の略中央部に水平状に横設された把持部Ｔ５とから構成されている。   Conventionally, as an embedding tray for preparing this type of histopathological specimen, the one shown in FIG. 15 has been frequently used. The embedding tray T includes a paraffin storage portion T1, a cassette support portion T2 for placing a horizontal cassette on the periphery thereof, and a cassette member for stopping the movement of the cassette standing on the periphery thereof. It consists of a stop wall T3 and a frame portion T4 provided horizontally around the periphery thereof, and further comprises a grip portion T5 provided horizontally in a substantially central portion of the frame portion T4 in the longitudinal direction.

また、近年では、方形の容器からなるパラフィン収容部とその周縁に設けられたパラフィンブロック付着体の載置部とからなり、前記載置部が少なくとも２個設けられており、サイズの異なる２種類以上のカセット等に対応できる病理組織検査標本作成用トレイが知られている（例えば、特許文献１参照）。   Further, in recent years, it is composed of a paraffin storage portion formed of a rectangular container and a placement portion for a paraffin block adhering body provided at the periphery thereof, and at least two placement portions are provided, and two types having different sizes are provided. A tray for preparing a histopathological examination specimen that can handle the above cassettes is known (for example, see Patent Document 1).

上記病理組織検査標本作成用トレイを使用して顕微鏡標本を作製するには、図１６、図１７に示すように、まず、カセット本体Ｃ１内に採取した検体Ｓを収容して蓋Ｃ２を取り付け、記録部Ｃ３に被験者名等のデーターを記録しておく。次いで、カセット本体Ｃ１の底部や蓋Ｃ２に穿設された透孔Ｃ４からホルマリンを流入させて検体Ｓを固定処理し、次いでアルコールにより検体Ｓの水分を除去し、キシレンにより後述する液状パラフィンとの親和性を付与する。   In order to prepare a microscope specimen using the above-mentioned pathological examination specimen preparation tray, first, as shown in FIGS. 16 and 17, the specimen S collected in the cassette body C1 is accommodated and a lid C2 is attached. Data such as the subject name is recorded in the recording unit C3. Next, formalin is introduced from the bottom of the cassette body C1 and the through hole C4 formed in the lid C2 to fix the specimen S, and then the moisture of the specimen S is removed with alcohol, and the liquid paraffin described later with xylene is removed. Confer affinity.

次に、図１８に示すとおり、検体ＳをトレイＴに移してパラフィン収容部Ｔ１に溶融パラフィンを注ぎ入れ、次いでカセット支承部Ｔ２にカセット本体Ｃ１の底部を載せ、カセット本体Ｃ１が浮き上がらないように指で押えつけて上方からパラフィンＰを注ぎ足す。次いで、パラフィンＰを冷却固化させた後、トレイＴを取り除くことにより、図１９に示したように、検体Ｓを包埋したパラフィンＰがカセット本体Ｃ１の底部に付着してなるパラフィンブロックＢを得る。その後、図示しないが、ミクロトームにカセットブロックＢをカセット本体Ｃ１の開口部が下に向くように固定された状態でパラフィンに包埋された検体Ｓをスライスして薄片を得て、これに染色等の所定の処理を施すことにより顕微鏡標本を得るのである。   Next, as shown in FIG. 18, the specimen S is transferred to the tray T and molten paraffin is poured into the paraffin container T1, and then the bottom of the cassette body C1 is placed on the cassette support T2 so that the cassette body C1 does not float. Hold it with your finger and add paraffin P from above. Next, after the paraffin P is cooled and solidified, the tray T is removed to obtain a paraffin block B in which the paraffin P in which the specimen S is embedded adheres to the bottom of the cassette body C1, as shown in FIG. . Thereafter, although not shown, the specimen S embedded in paraffin is sliced in a state where the cassette block B is fixed to the microtome so that the opening of the cassette body C1 faces downward, and a slice is obtained. The microscope specimen is obtained by performing the predetermined processing.

しかしながら、上記の方法では周囲を取り囲むカセット係止壁Ｔ３のためにカセット本体Ｃ１と包埋トレイＴとの間に溶融パラフィンに含まれる空気や溶融パラフィンの注入の際に巻き込んだ空気が滞留しやすく、この滞留した空気の押し出しが不十分になり、カセット本体Ｃ１の底部に気泡Ａが付着し、この気泡Ａがカセット本体Ｃ１とパラフィンＰとの付着を妨げ、付着力を低下させる場合がある。カセット本体Ｃ１とパラフィンＰとの付着力が低下すると、検体Ｓのスライス中にパラフィンＰがカセット本体Ｃ１の底部から剥離してしまい、目的とする薄片を得ることができなくなり、貴重な検体Ｓを台無しにするという重大な結果を招くことになる。
特開２００６−３００７４５号公報 However, in the above method, because of the cassette locking wall T3 surrounding the periphery, the air contained in the molten paraffin or the air entrained during the injection of the molten paraffin tends to stay between the cassette body C1 and the embedding tray T. In some cases, the accumulated air is not sufficiently pushed out, and air bubbles A adhere to the bottom of the cassette body C1, and the air bubbles A hinder the adhesion between the cassette body C1 and the paraffin P, thereby reducing the adhesion force. When the adhesion between the cassette body C1 and the paraffin P decreases, the paraffin P peels off from the bottom of the cassette body C1 during the slicing of the specimen S, and the target slice cannot be obtained. It will have serious consequences of ruining.
JP 2006-300745 A

本発明者らは、かかる実情に鑑み、上記問題点を解消するべく鋭意研究の結果、係止壁の角部に空気抜きのための切欠部を設ければ、パラフィン収容部内に滞留する空気を容易に排出でき、上記問題点が一挙に解消されることを見い出し、本発明を完成するに至った。   As a result of intensive studies to solve the above problems, the present inventors have made it easy to remove the air staying in the paraffin container by providing a notch for venting the corner of the locking wall. It was found that the above problems could be solved at once, and the present invention was completed.

本発明は上記目的を達成するためになされたもので、本発明の請求項１は、底部とその周りに立設された側壁とからなるパラフィン収容部と、該収容部の上方外側に設けられたカセット支承部と、該支承部の上方外側に立設された３辺の係止壁と１辺の係止爪とを具備し、前記係止壁のうち対向する係止壁の上端から把持部が外方向に延設されており、係止壁の角部には空気抜きのための切欠部が設けられていることを特徴とする病理組織検査標本作成用の包埋トレイを内容とする。   The present invention has been made in order to achieve the above object, and claim 1 of the present invention is provided on the upper outer side of a paraffin storage portion comprising a bottom portion and a side wall standing around the bottom portion. A cassette support part, and a three-sided locking wall and a one-side locking claw erected on the upper outer side of the supporting part, and gripped from the upper ends of the opposing locking walls among the locking walls. An embedding tray for preparing a histopathological specimen is characterized in that the portion extends outward and a notch for venting air is provided at the corner of the locking wall.

本発明の請求項２は、切欠部がスリット状であることを特徴とする請求項１に記載の病理組織検査標本作成用の包埋トレイを内容とする。   According to a second aspect of the present invention, the embedding tray for preparing a histopathological examination specimen according to the first aspect is characterized in that the notch is slit-shaped.

本発明の請求項３は、切欠部が上側が広く下側が狭いＶカット状であることを特徴とする請求項１に記載の病理組織検査標本作成用の包埋トレイを内容とする。   According to a third aspect of the present invention, there is provided an embedding tray for preparing a histopathological specimen according to the first aspect, characterized in that the notch has a V-cut shape whose upper side is wide and whose lower side is narrow.

本発明の請求項４は、把持部が枠状であることを特徴とする請求項１乃至請求項３のいずれかに記載の病理組織検査標本作成用の包埋トレイを内容とする。   According to a fourth aspect of the present invention, there is provided an embedding tray for preparing a histopathological specimen as set forth in any one of the first to third aspects, wherein the gripping portion has a frame shape.

本発明の請求項５は、把持部が斜め上方向に延設されていることを特徴とする請求項１乃至請求項４のいずれかに記載の病理組織検査標本作成用の包埋トレイを内容とする。   According to a fifth aspect of the present invention, the embedding tray for preparing a histopathological specimen according to any one of the first to fourth aspects includes a gripping portion extending obliquely upward. And

本発明の病理組織検査標本作成用の包埋トレイは、係止壁の角部に空気抜きのための切欠部を設けることにより、パラフィン収容部内に滞留する空気が抜け易くなるので、カセット本体の底部に気泡が付着し難くなり、カセットとパラフィンの付着性が向上し、検体のスライス中にパラフィンがカセットから剥離するといったトラブルが防止される。   The embedding tray for preparing a histopathological specimen according to the present invention is provided with a cutout portion for venting air at the corner of the locking wall, so that air staying in the paraffin housing portion can be easily removed. Air bubbles are less likely to adhere to the cassette, the adhesion between the cassette and the paraffin is improved, and troubles such as separation of the paraffin from the cassette during the slice of the specimen are prevented.

切欠部の形状としては、スリット状や、Ｖカット状が好ましい。   As the shape of the notch, a slit shape or a V-cut shape is preferable.

係止爪又は係止壁の上端から把持部を横設すれば、包埋トレイを取り扱いやすくなり、作業性が向上する。この場合、把持部を内部に穴を有する枠状とすることにより、把持部によって空気の排出が殆ど妨げられることがなく、また、万一、パラフィンが上昇してきたとしても枠内の穴より容易に排出されるので好ましい。更に、把持部を斜め上方向に延設することにより、例えば、机上面や、ホットプレート面で作業する場合には、この机上面又はホットプレート面から距離が取れるので把持し易く、またホットプレートに触れ火傷をしたりする恐れも小さくなる。   If the gripping portion is provided laterally from the upper end of the locking claw or the locking wall, the embedding tray can be easily handled and workability is improved. In this case, by making the gripping part into a frame shape having a hole inside, the gripping part hardly disturbs the discharge of air, and even if paraffin rises, it is easier than the hole in the frame. Is preferable. Furthermore, by extending the gripping portion diagonally upward, for example, when working on the desk top surface or hot plate surface, it is easy to grip because the distance from the desk top surface or the hot plate surface can be secured. There is less risk of touching and burning.

本発明の包埋トレイ１は、その代表的な一例を図１乃至図４に示したように、底部３とその周りに立設された側壁４とからなるパラフィン収容部２と、該収容部２の上方外側に設けられたカセット支承部５と、該支承部５の上方外側に立設された３辺の係止壁７と１辺の係止爪６とを具備し、前記係止壁７のうち対向する係止壁７の上端から把持部９が外方向に延設されており、係止壁の角部には空気抜きのための切欠部８が設けられていることを特徴とする。   The embedding tray 1 of the present invention has a paraffin container 2 composed of a bottom 3 and a side wall 4 standing around it, as shown in FIGS. 2 is provided with a cassette support part 5 provided on the upper outer side of 2, a locking wall 7 on three sides standing on the upper outer side of the support part 5, and a locking claw 6 on one side, A grip portion 9 is extended outwardly from the upper end of the opposing locking wall 7 of 7, and a notch portion 8 for venting air is provided at a corner of the locking wall. .

本発明の包埋トレイ１は溶融パラフィンに耐える耐熱性素材から作られ、かかる素材としては、ステンレス等の金属、ポリエステル、ポリアミド、ポリカーボネート、ポリアセタール等の樹脂等が挙げられるが、熱伝導性が良好である点で金属が好ましい。   The embedding tray 1 of the present invention is made of a heat-resistant material that can withstand molten paraffin. Examples of such a material include metals such as stainless steel, resins such as polyester, polyamide, polycarbonate, and polyacetal. In this respect, a metal is preferable.

パラフィン収容部２は、パラフィンブロックＢの脱型を容易にするため、通常、側壁４が底部３から開口部に向かって末広がりのテーパー状の容器からなる。   In order to facilitate the demolding of the paraffin block B, the paraffin storage unit 2 is usually formed of a tapered container whose side wall 4 extends from the bottom 3 toward the opening.

パラフィン収容部２の上方外側には、カセット本体を載置するためのカセット支承部５が設けられる。カセット支承部５はカセット本体を安定に載置できるかぎり特に限定されないが、通常、パラフィン収容部２の周囲やコーナー部に設けられる。   A cassette support portion 5 for placing the cassette main body is provided on the upper outer side of the paraffin storage portion 2. The cassette support portion 5 is not particularly limited as long as the cassette body can be stably placed, but is usually provided around the paraffin storage portion 2 or in a corner portion.

カセット支承部５の上方外側には、カセットＣを包埋トレイ１の上に定置して、その滑動（横滑り）を防止するための係止壁７及び係止爪６が設けられるが、本発明の包埋トレイ１では、係止壁７が３辺に立設されるとともに、係止爪６が１辺に立設されている。従って、例えば、図１６、図１７に記載されているような斜面状の記録部Ｃ３を有するカセットＣの場合は、その記録部Ｃ３が係止爪６側になるように載置してパラフィンブロックを作成すると、記録部Ｃ３がパラフィンで覆われることがなく、視認性を妨げることがない。   On the upper outer side of the cassette support portion 5, there are provided a locking wall 7 and a locking claw 6 for fixing the cassette C on the embedding tray 1 and preventing its sliding (side slip). In the embedding tray 1, the locking wall 7 is erected on three sides, and the locking claw 6 is erected on one side. Therefore, for example, in the case of a cassette C having a sloped recording portion C3 as described in FIGS. 16 and 17, the cassette C is placed so that the recording portion C3 is on the locking claw 6 side and the paraffin block is placed. The recording portion C3 is not covered with paraffin, and visibility is not hindered.

係止爪６の形状、大きさ、個数は特に限定されないが、余り幅が大きくなると、その部分に冷却固化したパラフィンが盛り上がって記録部Ｃ３を覆ってしまうことがあり、また余り幅が小さいとカセット本体Ｃ１の滑動を防止する効果が小さくなるので、通常幅１〜５ｍｍ程度、好ましくは２〜５ｍｍ程度で、係止爪の幅の合計は側壁の長さの１／５程度以下、更には１／２０程度以下が好ましい。一辺当たりの係止爪６の幅の合計が側壁４の長さの１／５を超えると、空気の押し出しや余分のパラフィンの排出がしにくくなる。   The shape, size, and number of the locking claws 6 are not particularly limited. However, if the extra width is large, the cooled and solidified paraffin may rise to cover the recording portion C3, and if the extra width is small. Since the effect of preventing the cassette body C1 from sliding is reduced, the width is usually about 1 to 5 mm, preferably about 2 to 5 mm, and the total width of the locking claws is about 1/5 or less of the length of the side wall. It is preferably about 1/20 or less. If the total width of the locking claws 6 per side exceeds 1/5 of the length of the side wall 4, it will be difficult to push out air and discharge excess paraffin.

係止爪６が設けられていない３辺には係止壁７が立設される。このため、立設された係止壁７にカセットＣの側壁を押し当てるようにして包埋トレイ１上に載置できるので、カセットＣの位置合わせが容易である。   Locking walls 7 are erected on the three sides where the locking claws 6 are not provided. For this reason, the cassette C can be placed on the embedding tray 1 such that the side wall of the cassette C is pressed against the standing locking wall 7, so that the alignment of the cassette C is easy.

係止壁７の高さはカセット支承部５の上に載置したカセット本体の滑動を防止できれば特に限定されないが、カセット本体の外壁面には付着するパラフィンを減らすために、低く（例えば２〜４ｍｍ程度）形成するほうが好ましい。   The height of the locking wall 7 is not particularly limited as long as the sliding of the cassette body placed on the cassette support 5 can be prevented. However, the height of the locking wall 7 is low (for example, 2 to 2) in order to reduce paraffin adhering to the outer wall surface of the cassette body. (About 4 mm) is preferable.

係止壁７も係止爪６と同様、カセット本体Ｃ１の滑動を抑えてカセット支承部５に安定に載置する機能を有する点で共通するが、カセット本体Ｃ１と包埋トレイ１の間に滞留する空気や余分なパラフィンを排出する機能が劣る点で異なる。このため、３辺に係止壁７を設ける本発明において、係止壁の角部、即ち、隣接する２辺に係止壁７が設けられている角部では、特に空気が滞留しやすい。この点、本発明では係止壁の角部に切欠部８が設けられているので、角部に滞留した空気はこの切欠部８から排出されるので、カセット本体Ｃ１の底部とパラフィンとの間の気泡もスムースに排出される。   The locking wall 7 is the same as the locking claw 6 in that it has the function of suppressing the sliding of the cassette body C1 and stably placing it on the cassette support portion 5, but between the cassette body C1 and the embedding tray 1 is common. The difference is that the function of discharging stagnant air and excess paraffin is poor. For this reason, in the present invention in which the locking walls 7 are provided on the three sides, air tends to stay particularly at the corners of the locking walls, that is, the corners where the locking walls 7 are provided on the two adjacent sides. In this respect, in the present invention, since the notch 8 is provided at the corner of the locking wall, the air staying at the corner is discharged from the notch 8, so that the space between the bottom of the cassette body C1 and the paraffin is removed. Bubbles are also discharged smoothly.

切欠部８の形状は、包埋トレイ１内に滞留する空気を好適に排出できるかぎり特に限定されないが、スリット型やＶカット型が例示できる。
切欠部８の形状を上側が広く下側が狭いＶカット型とする場合、上方に行く程抵抗が小さくなるので、空気が抜けやすくなり、空気や気泡はスムーズに排出される。 The shape of the notch 8 is not particularly limited as long as the air staying in the embedding tray 1 can be suitably discharged, but a slit type or a V cut type can be exemplified.
When the shape of the notch 8 is a V-cut type with the upper side being wide and the lower side being narrow, the resistance becomes smaller toward the upper side, so that air is easily removed and air and bubbles are discharged smoothly.

切欠部８の大きさは、包埋トレイ１内で滞留する空気を排出できる程度であれば特に限定されないが、幅Ｌ１を通常、０．１〜４ｍｍ程度、好ましくは０．１〜２ｍｍ程度、深さを該切欠部８の下端がカセット支承部５より０．１〜２ｍｍ上方になる程度とすれば、包埋トレイ１内の空気や気泡を十分排出でき、カセット本体Ｃ１の底部への気泡の付着を抑えることができるので好ましい。   Although the magnitude | size of the notch part 8 will not be specifically limited if it is the grade which can discharge | emit the air which retains in the embedding tray 1, Usually, width L1 is about 0.1-4 mm, Preferably it is about 0.1-2 mm, If the depth is set so that the lower end of the notch 8 is 0.1 to 2 mm above the cassette support 5, air and bubbles in the embedding tray 1 can be sufficiently discharged, and bubbles to the bottom of the cassette body C 1 can be discharged. It is preferable because it can suppress the adhesion of.

本発明の包埋トレイ１を扱いやすくするため係止壁７の上端から把持部９が設けられる。把持部９の形状は内側に穴のあいた枠状とすることにより、内側の穴から空気を押し出し、また余分のパラフィンを排出できるようにするのが好ましい。
把持部９は、包埋トレイ１から水平方向に延接しても良いし、斜め上方向に向けて延設することもできる。斜め上方に延接すると、例えば机上で作業する場合は机上面からの距離が取れるので把持しやすく、また、例えば包埋トレイ１をホットプレート上で使用する場合でも、把持部９とホットプレートの間の距離が大きくなるので、包埋トレイ１を把持する際にホットプレートなどに手指が触れ、火傷をする等の危険性が減少する。斜め上方向の把持部９は、例えば、パラフィン収容部２が浅い場合に特に有効である。 In order to make the embedding tray 1 of the present invention easy to handle, a grip portion 9 is provided from the upper end of the locking wall 7. It is preferable that the shape of the grip portion 9 is a frame shape with a hole on the inner side so that air can be pushed out from the inner hole and excess paraffin can be discharged.
The grip portion 9 may extend in the horizontal direction from the embedding tray 1 or may extend in an obliquely upward direction. When extending obliquely upward, for example, when working on a desk, the distance from the top surface of the desk can be increased so that it can be easily gripped. For example, even when the embedding tray 1 is used on a hot plate, the grip 9 and the hot plate Since the distance between them increases, the risk of burns due to the fingers touching the hot plate or the like when holding the embedding tray 1 is reduced. The diagonally upward grip 9 is particularly effective when the paraffin container 2 is shallow, for example.

パラフィン収容部２の形状を左右非対称とすることにより、ミクロトームでスライスされた薄片の左右が明確に区別されるので、作業性が高められ、また左右誤認により検体を取り違えるといったトラブルが防止されるので、検査の信頼性が向上する。
左右非対称とする方法は特に限定されないが、例えば、パラフィン収容部２の角部のうち一箇所のアール半径を変える（大きくする）又は三角形状に切り欠く方法や、側壁４のうち一辺を波形や円弧形にするなどの方法が採用できる。 By making the shape of the paraffin container 2 asymmetrical, the right and left of the slice sliced with the microtome are clearly distinguished, so that workability is improved and troubles such as mistaking the specimen due to misidentification of the left and right are prevented. , Improve the reliability of inspection.
The method of making the left-right asymmetric is not particularly limited, but for example, a method of changing (enlarging) the radius of one of the corners of the paraffin container 2 or cutting it into a triangular shape, A method such as arc shape can be adopted.

本発明の包埋トレイ１とともに用いるカセットは、カセット本体の底面に透孔を有するカセットであれば特に限定はないが、図１６、図１７に示したような斜面状の記録部Ｃ３を備えたカセットに対して、特に有効である。   The cassette used with the embedding tray 1 of the present invention is not particularly limited as long as it is a cassette having a through hole in the bottom surface of the cassette body, but includes a sloped recording portion C3 as shown in FIGS. This is particularly effective for cassettes.

また、本発明の包埋トレイ１は図１８、図１９に例示された一般的な方法で用いることができるが、溶融パラフィンの流動性を高め、空気を排出しやすくするため、予め包埋トレイ１を暖めておくか、パラフィン注入中または注入後に包埋トレイ１を一時的に適温まで加熱するのが好ましい。   Further, the embedding tray 1 of the present invention can be used in the general method illustrated in FIGS. 18 and 19. However, in order to enhance the fluidity of the molten paraffin and to easily discharge the air, the embedding tray 1 is used in advance. It is preferable to warm 1 or to temporarily heat the embedding tray 1 to an appropriate temperature during or after paraffin injection.

以下、本発明の実施例を図面に基づいて更に詳細に説明するが、本発明はかかる実施例のみに限定されないことは云うまでもない。   Hereinafter, examples of the present invention will be described in more detail with reference to the drawings. However, it is needless to say that the present invention is not limited to the examples.

実施例１
本実施例の包埋トレイ１は、図１乃至図４に示すように、底部３とその周りに立設された側壁４とからなり、平面視左下側（図１内の方向。本実施例において以下同じ）の角部が三角形状に切り欠かれた形状のパラフィン収容部２と、該収容部２の上方外側に設けられ、平面視左右側で広く、平面視上下側で狭いカセット支承部５と、該支承部５の上方外側に立設された３辺の係止壁７と１辺の係止爪６とを具備する。また、実施例１に係る包埋トレイ１の縦横比（把持部９を除く）は、凡そ１：１．４である。
前記係止壁７のうち対向する係止壁７の上端から枠型の、即ち、中央部に穴が設けられた把持部９が外方向且つ水平に延設されている。
係止壁の角部には、図４に示したとおり、Ｖカット状の切欠部８が空気抜きのために設けられており、その大きさは上端部における幅Ｌ１が２ｍｍ、深さが３．５ｍｍであり、カセット支承部５から切欠部８下端間での長さは０．５ｍｍである。 Example 1
As shown in FIGS. 1 to 4, the embedding tray 1 according to the present embodiment includes a bottom portion 3 and a side wall 4 erected around the bottom portion 3, and the lower left side in a plan view (the direction in FIG. 1). The same applies to the following), the paraffin container 2 having a triangular shape cut out in a triangular shape, and a cassette support that is provided on the upper outer side of the container 2 and is wide on the left and right sides in plan view and narrow on the top and bottom sides in plan view. 5, three side locking walls 7 erected on the upper outside of the support portion 5, and one side locking claw 6. Further, the aspect ratio of the embedding tray 1 according to the first embodiment (excluding the grip portion 9) is about 1: 1.4.
From the upper end of the locking wall 7 of the locking wall 7, a frame-shaped grip 9 having a hole in the center is extended outward and horizontally.
As shown in FIG. 4, a V-cut-shaped notch 8 is provided at the corner of the locking wall for venting air. The length between the cassette support 5 and the lower end of the notch 8 is 0.5 mm.

実施例２
本実施例の包埋トレイ１は、図５乃至図８に示すように、実施例１の包埋トレイ１とほぼ同様であるが、把持部９が斜め上約４５°の方向に延接されている点、係止壁の角部に設けられた切欠部８の形状がスリット状である点、及びパラフィン収容部２の形状が異なる。
本実施例における切欠部８の大きさは、幅が１ｍｍ、深さが３．５ｍｍであり、カセット支承部５から切欠部８下端間での長さは０．５ｍｍである。 Example 2
The embedding tray 1 of the present embodiment is substantially the same as the embedding tray 1 of the first embodiment as shown in FIGS. 5 to 8, but the grip portion 9 extends obliquely upward at a direction of about 45 °. The shape of the notch 8 provided at the corner of the locking wall is a slit, and the shape of the paraffin container 2 is different.
In this embodiment, the notch 8 has a width of 1 mm and a depth of 3.5 mm, and the length between the cassette support 5 and the lower end of the notch 8 is 0.5 mm.

実施例３
本実施例の包埋トレイ１は、図９乃至図１１に示すように、実施例１の包埋トレイ１とほぼ同様であるが、パラフィン収容部２、カセット支承部５の形状、及びＶカット状の切欠部８の上端部における幅Ｌ１を４ｍｍとした点で異なる。また、本実施例に係る包埋トレイ１の縦横比（把持部９を除く）は、凡そ１：３である。 Example 3
The embedding tray 1 of the present embodiment is substantially the same as the embedding tray 1 of the first embodiment as shown in FIGS. 9 to 11, but the shape of the paraffin container 2, the cassette support portion 5, and the V-cut. The difference is that the width L1 at the upper end of the cutout 8 is 4 mm. Further, the aspect ratio of the embedding tray 1 according to the present embodiment (excluding the grip portion 9) is about 1: 3.

実施例４
本実施例の包埋トレイ１は、図１２乃至図１４に示すように、実施例２の包埋トレイ１とほぼ同様であるが、パラフィン収容部２及びカセット支承部５の形状が異なる。また、本実施例に係る包埋トレイ１の縦横比（把持部９を除く）は、凡そ１：３である。 Example 4
The embedding tray 1 of the present embodiment is substantially the same as the embedding tray 1 of the second embodiment as shown in FIGS. 12 to 14, but the shapes of the paraffin storage portion 2 and the cassette support portion 5 are different. Further, the aspect ratio of the embedding tray 1 according to the present embodiment (excluding the grip portion 9) is about 1: 3.

叙上のとおり、本発明の病理組織検査標本作成用の包埋トレイは、パラフィンブロック付着体を作成する際にカセットと包埋トレイの間に滞留する空気が排出されて冷却固化パラフィンとカセット本体との結合が強くなるため、検体をスライスする時にパラフィンがカセット本体から剥離するトラブルが防止され、病理組織検査標本を作成する作業性や検査の信頼性が大幅に高められる。   As described above, the embedding tray for preparing a histopathological specimen according to the present invention is cooled solidified paraffin and the cassette body by discharging air staying between the cassette and the embedding tray when creating the paraffin block adhering body. Therefore, the trouble that the paraffin is peeled off from the cassette body when the specimen is sliced is prevented, and the workability for preparing the histopathological specimen and the reliability of the examination are greatly improved.

本発明の包埋トレイの実施例１を示す平面図である。It is a top view which shows Example 1 of the embedding tray of this invention. 実施例１の正面図である。1 is a front view of Example 1. FIG. 実施例１の右側面図である。2 is a right side view of Example 1. FIG. 図１における包埋トレイを矢印の方向から見た部分拡大図である。It is the elements on larger scale which looked at the embedding tray in FIG. 1 from the direction of the arrow. 本発明の包埋トレイの実施例２を示す平面図である。It is a top view which shows Example 2 of the embedding tray of this invention. 実施例２の正面図である。6 is a front view of Example 2. FIG. 実施例２の右側面図である。6 is a right side view of Example 2. FIG. 図５における包埋トレイを矢印の方向から見た部分拡大図である。It is the elements on larger scale which looked at the embedding tray in FIG. 5 from the direction of the arrow. 本発明の包埋トレイの実施例３を示す平面図である。It is a top view which shows Example 3 of the embedding tray of this invention. 実施例３の正面図である。6 is a front view of Example 3. FIG. 実施例３の右側面図である。6 is a right side view of Example 3. FIG. 本発明の包埋トレイの実施例３を示す平面図である。It is a top view which shows Example 3 of the embedding tray of this invention. 実施例３の正面図である。6 is a front view of Example 3. FIG. 実施例３の右側面図である。6 is a right side view of Example 3. FIG. 従来の包埋トレイの一例を示す斜視図である。It is a perspective view which shows an example of the conventional embedding tray. カセットの一例を示す斜視図である。It is a perspective view which shows an example of a cassette. カセット内に検体を入れた状態を示す断面図である。It is sectional drawing which shows the state which put the test substance in the cassette. 顕微鏡標本の作製方法を示す説明図である。It is explanatory drawing which shows the preparation methods of a microscope specimen. 顕微鏡標本の作製方法を示す説明図である。It is explanatory drawing which shows the preparation methods of a microscope specimen.

符号の説明Explanation of symbols

１ 包埋トレイ
２ パラフィン収容部
３ 底部
４ 側壁
５ カセット支承部
６ 係止爪
７ 係止壁
８ 切欠部
９ 把持部
Ｃ カセット
Ｃ１ 本体
Ｃ２ 蓋
Ｃ３ 記録部
Ｃ４ 透孔
Ｐ パラフィン
Ｓ 検体
Ｔ 従来のトレイ
Ｔ１ パラフィン収容部
Ｔ２ カセット支承部
Ｔ３ カセット係止壁
Ｔ４ 額縁部
Ｔ５ 把持部
Ｂ パラフィンブロック
Ａ 気泡
Ｌ１ 切欠部の幅 DESCRIPTION OF SYMBOLS 1 Embedment tray 2 Paraffin storage part 3 Bottom part 4 Side wall 5 Cassette support part 6 Locking claw 7 Locking wall 8 Notch part 9 Grasping part C Cassette C1 Main body C2 Cover C3 Recording part C4 Through-hole P Paraffin S Specimen T Conventional tray T1 Paraffin storage part T2 Cassette support part T3 Cassette locking wall T4 Frame part T5 Grip part B Paraffin block A Bubble L1 Width of notch

Claims (5)

底部とその周りに立設された側壁とからなるパラフィン収容部と、該収容部の上方外側に設けられたカセット支承部と、該支承部の上方外側に立設された３辺の係止壁と１辺の係止爪とを具備し、前記係止壁のうち対向する係止壁の上端から把持部が外方向に延設されており、係止壁の角部には空気抜きのための切欠部が設けられていることを特徴とする病理組織検査標本作成用の包埋トレイ。   A paraffin storage portion comprising a bottom portion and a side wall standing around the bottom portion, a cassette support portion provided on the upper outer side of the storage portion, and a three-side locking wall provided on the upper outer side of the support portion And a locking claw on one side, a gripping portion is extended outward from the upper end of the opposing locking wall of the locking walls, and a corner for locking the air An embedding tray for preparing a histopathological specimen, which is provided with a notch. 切欠部がスリット状であることを特徴とする請求項１に記載の病理組織検査標本作成用の包埋トレイ。   The embedding tray for preparing a histopathological specimen according to claim 1, wherein the notch is slit-shaped. 切欠部が上側が広く下側が狭いＶカット状であることを特徴とする請求項１に記載の病理組織検査標本作成用の包埋トレイ。   2. The embedding tray for preparing a histopathological specimen according to claim 1, wherein the notch has a V-cut shape having an upper side and a lower side that is narrow. 把持部が枠状であることを特徴とする請求項１乃至請求項３のいずれかに記載の病理組織検査標本作成用の包埋トレイ。   The embedding tray for preparing a histopathological specimen according to any one of claims 1 to 3, wherein the gripping portion has a frame shape. 把持部が斜め上方向に延設されていることを特徴とする請求項１乃至請求項４のいずれかに記載の病理組織検査標本作成用の包埋トレイ。   The embedding tray for preparing a histopathological examination specimen according to any one of claims 1 to 4, wherein the gripping portion extends obliquely upward.
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JP2011247647A (en) * 2010-05-24 2011-12-08 Tanizaki Teiji Mount for sample fixation and transfer and sample embedding fixation supporting agent using two kinds of polymers of different shapes/functions and using method thereof
JP2011247640A (en) * 2010-05-24 2011-12-08 Tanizaki Teiji Unit construct device for forming embedding block for biological sample, including independent basket for biological sample processing that can perform fixation, transfer and liquid chemical processing of biological sample and be unit-connected and fitted with embedding frame-like base body, unit connected and fitted construct cassette for biological sample and burr-free embedding tray which is the unit construct device
JP2016194533A (en) * 2013-01-14 2016-11-17 ソン ミ ジョン、 Embedding mold and embedding assembly for biopsy
CN111238911A (en) * 2020-02-10 2020-06-05 大连医科大学 Special perpendicular embedding case of fault plastify
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JP2011247647A (en) * 2010-05-24 2011-12-08 Tanizaki Teiji Mount for sample fixation and transfer and sample embedding fixation supporting agent using two kinds of polymers of different shapes/functions and using method thereof
JP2011247640A (en) * 2010-05-24 2011-12-08 Tanizaki Teiji Unit construct device for forming embedding block for biological sample, including independent basket for biological sample processing that can perform fixation, transfer and liquid chemical processing of biological sample and be unit-connected and fitted with embedding frame-like base body, unit connected and fitted construct cassette for biological sample and burr-free embedding tray which is the unit construct device
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CN111238911A (en) * 2020-02-10 2020-06-05 大连医科大学 Special perpendicular embedding case of fault plastify
WO2022071400A1 (en) * 2020-09-30 2022-04-07 株式会社常光 Cassette holder
JP7068738B1 (en) * 2020-09-30 2022-05-17 株式会社常光 Cassette holder

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