JP2008543936A - にきびの治療方法発明の分野 - Google Patents
にきびの治療方法発明の分野 Download PDFInfo
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- JP2008543936A JP2008543936A JP2008518272A JP2008518272A JP2008543936A JP 2008543936 A JP2008543936 A JP 2008543936A JP 2008518272 A JP2008518272 A JP 2008518272A JP 2008518272 A JP2008518272 A JP 2008518272A JP 2008543936 A JP2008543936 A JP 2008543936A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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Abstract
【解決手段】当該方法は、尋常性座瘡に苦しむ者に対し体重キログラム当たり、約0.5〜約1.5ミリグラムのテトラサイクリン系抗生剤を経口投与することからなる。ここで経口テトラサイクリン系抗生剤が製薬上適切な送達手段に含有される。
【選択図】なし。
Description
Claims (27)
- 尋常性座瘡に苦しむ者に対し体重キログラム当たり、約0.5〜約1.5ミリグラムのテトラサイクリン系抗生剤を経口投与するステップであって、ここで、前記経口テトラサイクリン系抗生剤が製薬上適切な送達手段に含有される、前記ステップを含んで成る尋常性座瘡の治療方法。
- 経口テトラサイクリンの量が体重キログラム当たり、約0.7〜約1.3ミリグラムである、請求項1に記載の方法。
- 前記経口テトラサイクリン系抗生剤を負荷量なしで投与する、請求項1又は2に記載の方法。
- 前記経口テトラサイクリン系抗生剤がミノサイクリンである、請求項1又は2に記載の方法。
- 経口テトラサイクリンがミノサイクリンである、請求項3に記載の方法。
- 前記経口テトラサイクリン系抗生剤を1日に1回投与する、請求項4に記載の方法。
- 前記経口テトラサイクリンを1日に1回投与する、請求項5に記載の方法。
- 前記送達手段が前記経口テトラサイクリン系抗生剤を約1時間以内に約30〜約52%、約2時間以内に約53〜約84%、約4時間以内に少なくとも約85%放出する、請求項4に記載の方法。
- 前記送達手段が前記経口テトラサイクリン系抗生剤を約1時間以内に約30〜約52%、約2時間以内に約53〜約84%、約4時間以内に少なくとも約85%放出する、請求項5に記載の方法。
- 前記送達手段が前記経口テトラサイクリン系抗生剤を約1時間以内に約25〜約52%、約2時間以内に約53〜約89%、約4時間以内に少なくとも約90%放出する、請求項5に記載の方法。
- 前記送達手段が前記経口テトラサイクリン系抗生剤を約1時間以内に約25〜約52%、約2時間以内に約53〜約89%、約4時間以内に少なくとも約90%放出する、請求項4に記載の方法。
- 前記送達手段が前記経口テトラサイクリン系抗生剤を、投与後約2.75〜約4.0時間で血液中の抗生剤がCmaxに達するように放出する、請求項5に記載の方法。
- 投与後約3.0〜約3.75時間の間にCmaxに達する、請求項12に記載の方法。
- 前記送達手段が前記経口テトラサイクリン系抗生剤を、投与後約2.75〜約4.0時間で血液中の抗生剤がCmaxに達するように放出する、請求項4に記載の方法。
- 投与後約3.0〜約3.75時間の間にCmaxに達する、請求項14に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.3〜約0.5である、請求項5に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.35〜約0.45である、請求項5に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.36〜約0.40である、請求項5に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.3〜約0.5である、請求項4に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.35〜約0.45である、請求項4に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.36〜約0.40である、請求項4に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.3〜約0.5である、請求項6に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.35〜約0.45である、請求項6に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.36〜約0.40である、請求項6に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.3〜約0.5である、請求項7に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.35〜約0.45である、請求項7に記載の方法。
- 前記送達手段における速溶性キャリア対遅溶性キャリアの比が、約0.36〜約0.40である、請求項7に記載の方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/166,817 US7919483B2 (en) | 2005-06-24 | 2005-06-24 | Method for the treatment of acne |
PCT/US2006/023761 WO2007001961A2 (en) | 2005-06-24 | 2006-06-19 | Method for the treatment of acne |
Related Child Applications (1)
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JP2013146709A Division JP5744976B2 (ja) | 2005-06-24 | 2013-07-12 | にきびの治療方法発明の分野 |
Publications (2)
Publication Number | Publication Date |
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JP2008543936A true JP2008543936A (ja) | 2008-12-04 |
JP2008543936A5 JP2008543936A5 (ja) | 2009-12-17 |
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Application Number | Title | Priority Date | Filing Date |
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JP2008518272A Pending JP2008543936A (ja) | 2005-06-24 | 2006-06-19 | にきびの治療方法発明の分野 |
JP2013146709A Active JP5744976B2 (ja) | 2005-06-24 | 2013-07-12 | にきびの治療方法発明の分野 |
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JP2013146709A Active JP5744976B2 (ja) | 2005-06-24 | 2013-07-12 | にきびの治療方法発明の分野 |
Country Status (11)
Country | Link |
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US (6) | US7919483B2 (ja) |
EP (1) | EP1898925A4 (ja) |
JP (2) | JP2008543936A (ja) |
CN (1) | CN101208097A (ja) |
AU (1) | AU2006262428B2 (ja) |
CA (1) | CA2613273C (ja) |
IL (1) | IL188331A0 (ja) |
NO (1) | NO20080444L (ja) |
NZ (1) | NZ564093A (ja) |
WO (1) | WO2007001961A2 (ja) |
ZA (1) | ZA200802064B (ja) |
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JP2021509409A (ja) * | 2018-01-07 | 2021-03-25 | ドクター レディズ ラボラトリーズ リミテッド | 炎症性皮膚状態を処置するためのミノサイクリン |
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WO2012153884A1 (ko) * | 2011-05-12 | 2012-11-15 | (주)아모레퍼시픽 | 안정성이 향상된 여드름 개선용 조성물 |
JP2021509409A (ja) * | 2018-01-07 | 2021-03-25 | ドクター レディズ ラボラトリーズ リミテッド | 炎症性皮膚状態を処置するためのミノサイクリン |
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ZA200802064B (en) | 2009-09-30 |
US20080182825A2 (en) | 2008-07-31 |
US20080181945A2 (en) | 2008-07-31 |
EP1898925A2 (en) | 2008-03-19 |
JP5744976B2 (ja) | 2015-07-08 |
US20070275933A1 (en) | 2007-11-29 |
CA2613273C (en) | 2015-12-08 |
US20070254855A1 (en) | 2007-11-01 |
US20080182827A2 (en) | 2008-07-31 |
US20070225262A2 (en) | 2007-09-27 |
US20080182826A2 (en) | 2008-07-31 |
US20060293290A1 (en) | 2006-12-28 |
AU2006262428B2 (en) | 2012-02-23 |
US20080070872A1 (en) | 2008-03-20 |
US7919483B2 (en) | 2011-04-05 |
NZ564093A (en) | 2011-06-30 |
AU2006262428A1 (en) | 2007-01-04 |
WO2007001961A3 (en) | 2007-05-18 |
CN101208097A (zh) | 2008-06-25 |
CA2613273A1 (en) | 2007-01-04 |
JP2013213047A (ja) | 2013-10-17 |
NO20080444L (no) | 2008-01-23 |
EP1898925A4 (en) | 2009-07-29 |
US20070259039A1 (en) | 2007-11-08 |
IL188331A0 (en) | 2008-08-07 |
US20070270390A1 (en) | 2007-11-22 |
WO2007001961A2 (en) | 2007-01-04 |
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