JP2008280345A5 - - Google Patents

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Publication number
JP2008280345A5
JP2008280345A5 JP2008103209A JP2008103209A JP2008280345A5 JP 2008280345 A5 JP2008280345 A5 JP 2008280345A5 JP 2008103209 A JP2008103209 A JP 2008103209A JP 2008103209 A JP2008103209 A JP 2008103209A JP 2008280345 A5 JP2008280345 A5 JP 2008280345A5
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JP
Japan
Prior art keywords
topiramate
solid preparation
stabilizing
crystals
particle size
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008103209A
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Japanese (ja)
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JP5424571B2 (en
JP2008280345A (en
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Priority to JP2008103209A priority Critical patent/JP5424571B2/en
Priority claimed from JP2008103209A external-priority patent/JP5424571B2/en
Publication of JP2008280345A publication Critical patent/JP2008280345A/en
Publication of JP2008280345A5 publication Critical patent/JP2008280345A5/ja
Application granted granted Critical
Publication of JP5424571B2 publication Critical patent/JP5424571B2/en
Active legal-status Critical Current
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Claims (1)

トピラマートを含有する固形製剤の製造に用いるトピラマートとして、体積平均粒子径が1.0〜100.0μmのトピラマート結晶を用いることを特徴とするトピラマート含有固形製剤中のトピラマートの安定化方法。 A method for stabilizing topiramate in a topiramate-containing solid preparation , wherein topiramate crystals having a volume average particle size of 1.0 to 100.0 μm are used as the topiramate used in the production of a solid preparation containing topiramate.
JP2008103209A 2007-04-12 2008-04-11 Topiramate-containing solid preparation Active JP5424571B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008103209A JP5424571B2 (en) 2007-04-12 2008-04-11 Topiramate-containing solid preparation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007104853 2007-04-12
JP2007104853 2007-04-12
JP2008103209A JP5424571B2 (en) 2007-04-12 2008-04-11 Topiramate-containing solid preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013188248A Division JP6125957B2 (en) 2007-04-12 2013-09-11 Topiramate-containing solid preparation

Publications (3)

Publication Number Publication Date
JP2008280345A JP2008280345A (en) 2008-11-20
JP2008280345A5 true JP2008280345A5 (en) 2011-04-14
JP5424571B2 JP5424571B2 (en) 2014-02-26

Family

ID=40141447

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2008103209A Active JP5424571B2 (en) 2007-04-12 2008-04-11 Topiramate-containing solid preparation
JP2013188248A Active JP6125957B2 (en) 2007-04-12 2013-09-11 Topiramate-containing solid preparation
JP2016207609A Pending JP2017014289A (en) 2007-04-12 2016-10-24 Topiramate-containing solid preparation

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2013188248A Active JP6125957B2 (en) 2007-04-12 2013-09-11 Topiramate-containing solid preparation
JP2016207609A Pending JP2017014289A (en) 2007-04-12 2016-10-24 Topiramate-containing solid preparation

Country Status (1)

Country Link
JP (3) JP5424571B2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
CN108354930A (en) * 2010-05-11 2018-08-03 詹森药业有限公司 Include the pharmaceutical preparation of 1- (β-D- glucopyranosyls) -2- thienyl-methyl benzene derivatives
US10544135B2 (en) 2011-04-13 2020-01-28 Janssen Pharmaceutica Nv Process for the preparation of compounds useful as inhibitors of SGLT2
IN2013MU02470A (en) * 2013-07-25 2015-06-26 Cadila Healthcare Ltd
CN108379588A (en) * 2018-03-05 2018-08-10 合肥合源药业有限公司 Topiramate composition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU651244B2 (en) * 1991-09-19 1994-07-14 Mcneilab, Inc. Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3:4,5-bis-0-(1-methylethylidene)-beta-D- fructopyranose and (1-methylcyclohexyl)methanol
UA65607C2 (en) * 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Pharmaceutical composition (variants) and process for its preparation
EP1157682A1 (en) * 2000-05-25 2001-11-28 Cilag AG Blister package for topiramate tablets
DE10153078A1 (en) * 2001-10-30 2003-05-22 Degussa Use of granules based on pyrogenic silicon dioxide in pharmaceutical compositions
JP4469846B2 (en) * 2003-01-31 2010-06-02 エラン ファーマ インターナショナル，リミティド Nanoparticulate topiramate formulation
JP2007517063A (en) * 2003-12-29 2007-06-28 アルザ・コーポレーシヨン Novel pharmaceutical compositions and dosage forms of topiramate
ES2555066T3 (en) * 2006-11-17 2015-12-28 Supernus Pharmaceuticals, Inc. Topiramate sustained release formulations
CN102114002B (en) * 2006-12-04 2016-05-11 苏佩努斯制药公司 The immediate release formulation of the enhancing of Topiramate

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