JP2007520255A - 治療用超音波システム - Google Patents
治療用超音波システム Download PDFInfo
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- JP2007520255A JP2007520255A JP2006517355A JP2006517355A JP2007520255A JP 2007520255 A JP2007520255 A JP 2007520255A JP 2006517355 A JP2006517355 A JP 2006517355A JP 2006517355 A JP2006517355 A JP 2006517355A JP 2007520255 A JP2007520255 A JP 2007520255A
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Abstract
【選択図】図1
Description
この出願は、2002年8月2日出願の米国特許出願第10/211、418号(発明の名称「治療用超音波システム」)及び2002年9月20日出願の米国特許出願第09/251,227号(発明の名称「超音波カテーテルを変換器へ取り付けるコネクタ」)の一部継続出願である。これらの米国出願の全開示はここに完全に詳しく説明されるが、参照のためにここに組み入れられる。
第1吸収体98は遠位穴88内に座し、超音波伝達部材42受ける(すなわち、回りを囲む)穴を有する。吸収体100は近位穴84に座し、超音波伝達部材42受ける(すなわち、回りを囲む)穴を有する。言い換えれば、各吸収体98と100は超音波伝達部材42と、それぞれの穴88と84の間に置かれる。弾性材料で吸収体98,100を作ることができ、吸収体の非制限例はポリマ又はゴムを含む。代替的に、吸収体98,100をOリングの態様とすることができる。吸収体98,100は、横向きの微小運動を吸収して望ましくない横振動を最小にするように機能する。
Claims (47)
- 近位端と、遠位端と、内部を通って縦方向に延伸する主内腔とを有する細長い軟性カテーテルボディーと;
前記カテーテルボディーの前記主内腔を通って縦方向に延伸する超音波伝達部材であって、前記カテーテルボディーの前記遠位端に位置する遠位端を含む超音波伝達部材と;
前記主内腔の一部を通って縦方向に延伸し、前記カテーテルボディーの前記遠位端よりも前記カテーテルボディーの前記近位端の近くに位置するガイドワイヤポートにおいて終端するガイドワイヤ内腔と;
を含む超音波カテーテル。 - 請求項1の超音波カテーテルであって、前記カテーテルボディーの前記近位端に接続されたYコネクタをさらに含み、前記ガイドワイヤポートが前記Yコネクタに隣接して置かれている超音波カテーテル。
- 近位端と、遠位端と、内部を通って縦方向に延伸する少なくとも1つの内腔とを有する細長い軟性カテーテルボディーと;
カテーテルボディーの遠位端に置かれ、剛性かつラジオデンスの低密度材料から作られた遠位ヘッドと;
前記カテーテルボディーの前記少なくとも1つの内腔を通って縦方向に延伸し、前記遠位ヘッドに連結された遠位端を有する超音波伝達部材と;
を含む超音波カテーテル。 - 請求項3の超音波カテーテルであって、前記遠位ヘッドの材料はチタン合金である超音波カテーテル。
- 請求項3の超音波カテーテルであって、前記遠位ヘッドの材料はマグネシウム合金である超音波カテーテル。
- 請求項3の超音波カテーテルであって、前記遠位ヘッドの材料は、ABS、ポリカーボネート、ポリフェニレンオキシド、ポリアリーレート、ポリスルホン、及びそれらの混合物の群から選択される超音波カテーテル。
- 請求項3の超音波カテーテルであって、前記遠位ヘッドの材料は5g/cm3未満の平均密度を持つ超音波カテーテル。
- 請求項3の超音波カテーテルであって、前記遠位ヘッドの総質量は0.015グラム未満である超音波カテーテル。
- 請求項3の超音波カテーテルであって、前記遠位ヘッドの材料はアルミニウム合金である超音波カテーテル。
- 近位端と、遠位端と、内部を通って縦方向に延伸する主内腔とを有する細長い軟性カテーテルボディーと;
前記カテーテルボディーの前記主内腔を通って縦方向に延伸する超音波伝達部材であって、前記カテーテルボディーの前記遠位端に位置する遠位端を有する超音波伝達部材と;
前記主内腔の一部を通って縦方向に延伸し前記主内腔のほぼ中心に位置するガイドワイヤ内腔と;
を含む超音波カテーテル。 - 請求項10の超音波カテーテルであって、前記ガイドワイヤ内腔は前記カテーテルボディーの前記近位端に隣接したガイドワイヤポートで終端する超音波カテーテル。
- 請求項10の超音波カテーテルであって、前記ガイドワイヤ内腔は前記遠位ヘッドに取り付けられたガイドワイヤチューブによって画定される超音波カテーテル。
- 請求項12の超音波カテーテルであって、前記ガイドワイヤ内腔は前記遠位ヘッドのほぼ中心に置かれる超音波カテーテル。
- 近位端と、遠位ヘッドと、内部を通って縦方向に延伸する主内腔とを有する細長い軟性カテーテルボディーであって、前記遠位ヘッドは、基部と、該基部の内径より小さい内径を持つ穴を有する軟性カテーテルボディーと;
前記カテーテルボディーの前記主内腔を通って縦方向に延伸する超音波伝達部材であって、近位端と、前記カテーテルボディーの前記遠位ヘッドに位置する遠位端を含む超音波伝達部材と;
前記主内腔の一部を通って縦方向に延伸して前記遠位ヘッドの前記穴の基部内に延伸し前記遠位ヘッドの前記穴の前記遠位部の手前で終端するガイドワイヤ内腔と;
を含む超音波カテーテル。 - 請求項14の超音波カテーテルであって、前記ガイドワイヤ内腔は前記遠位ヘッドに取り付けられたガイドワイヤチューブによって画定される超音波カテーテル。
- 請求項14のカテーテル超音波カテーテルであって、前記ガイドワイヤ内腔は近位端と遠位端を有し、前記ガイドワイヤ内腔の前記近位端は前記カテーテルボディーの前記近位端に隣接して終端して前記カテーテルボディーに取り付けられている超音波カテーテル。
- 請求項14の超音波カテーテルであって、前記ガイドワイヤ内腔は近位端と遠位端を有し、前記ガイドワイヤ内腔の前記近位端は、前記カテーテルボディーの遠位端に隣接して終端しかつ前記カテーテルボディーに取り付けられている超音波カテーテル。
- 血管から粒子を取り除く方法であって:
近位端と、遠位先端と、内部を通って縦方向に延伸する内腔と、該内腔を通って縦方向に延伸する超音波伝達部材を有する超音波カテーテルを経皮的に血管に導入し;
血管の必要な治療位置に前記超音波カテーテルの前記遠位先端を位置決めし;
前記超音波カテーテルの外部に沿って流体の流れを前記必要な治療位置に導入し;
組織粒子を生じさせる超音波離解を前記必要な治療位置で開始し;
前記生じた組織粒子を前記流体と共に前記超音波カテーテルの前記内腔を通して前記遠位先端から前記近位端まで運んで前記血管の外に取り去ると共に、同時に、前記超音波伝達部材を冷却する;
ことを含む方法。 - 医療の間に治療位置を局所的にイメージ化する方法であって:
(a)近位端と、遠位先端と、内部を通って縦方向に延伸する内腔と、該内腔を通って縦方向に延伸する超音波伝達部材とを有する超音波カテーテルを経皮的に血管に導入し;
(b)損傷部を持つ血管の必要な治療位置に前記超音波カテーテルの前記遠位先端を位置決めし;
(c)前記必要な治療位置で超音波離解を開始し;
(d)前記超音波カテーテルの前記内腔に造影剤を注入して前記遠位先端から排出する;
ステップを含む方法。 - 請求項19の方法であって、ステップ(d)は、いつでも、ステップ(b)とステップ(c)の間に実行される方法。
- 請求項20の方法であって、ステップ(d)はステップ(c)における前記超音波離解が終了した後に実行される方法。
- 請求項19の方法であって、(g)前記カテーテルの前記遠位先端がガイドワイヤを前進させて前記損傷部を完全に横切らせるまで、ステップ(c)と(d)を繰り返すことをさらに含む方法。
- カテーテルの遠位端を形成する方法であって:カテーテルの遠位端を熱源上である時間曲げた形状に維持し;前記遠位端を冷却する;ステップを含む方法。
- 請求項23の方法であって、前記冷却ステップは、室温以下で冷却することを含む方法。
- 請求項23の方法であって、冷却ステップは、前記遠位端を塩水バス内で冷却することを含む方法。
- 請求項23の方法であって、前記カテーテルの材料を熱変形温度が100℃以下である材料にすることをさらに含む方法。
- 請求項23の方法であって、前記カテーテルの遠位端を熱源上である時間曲げた状態に維持する前に、延性ワイヤをカテーテルの遠位端に置くことをさらに含む方法。
- 請求項23の方法であって、前記熱源は蒸気源である方法。
- 近位端と、遠位端と、内部を通って縦方向に延伸する少なくとも1つの内腔とを有する軟性カテーテルボディーと;
前記カテーテルボディーの前記少なくとも1つの内腔を通って縦方向に延伸する超音波伝達部材であって、近位端と、前記カテーテルボディーの前記遠位端に位置する遠位端を含む超音波伝達部材と;
前記カテーテルボディーの前記近位端に位置され前記超音波伝達部材の前記近位端を超音波発生装置に連結する音波コネクタであって、前記近位端の前記超音波発生装置への連結が前記超音波発生装置の最大縦変位が生じる位置でなされている音波コネクタと;
を含む超音波カテーテル。 - 請求項29の超音波カテーテルであって、前記超音波伝達部材の一部と前記音波コネクタを囲む穴を備えるカテーテルノブをさらに含む超音波カテーテル。
- 請求項30の超音波カテーテルであって、前記カテーテルノブの前記穴の中に保持された吸収体をさらに含む超音波カテーテル。
- 請求項30の超音波カテーテルであって、前記音波コネクタは、前記超音波発生装置に接続される基部と、前記超音波伝達部材の前記近位端を受ける穴を画定する前部とを含む超音波カテーテル。
- 請求項31の超音波カテーテルあって、前記吸収体は複数のOリングを含む超音波カテーテル。
- 請求項31の超音波カテーテルあって、前記吸収体は、互いに隣接して置かれた少なくとも2個の異なった吸収体を含む超音波カテーテル。
- 請求項31の超音波カテーテルあって、前記吸収体は、互いに離間して置かれた2個の吸収体を含む超音波カテーテル。
- 近位端と、遠位端と、内部を通って縦方向に延伸する少なくとも1つの内腔とを有する細長い軟性カテーテルボディーと;
前記カテーテルボディーの前記少なくとも1つの内腔を通って縦方向に延伸する超音波伝達部材であって、音波コネクタに取り付けられた近位端と、前記カテーテルボディーの前記遠位端に取り付けられた遠位端を含む超音波伝達部材と;
前記超音波伝達部材を超音波発生装置に連結する音波コネクタであって、前記超音波伝達部材が取り付けられる遠位穴と、平坦な近位表面を有する中心部と、前記近位表面から延伸して離間し前記超音波発生装置に取り付けられたねじ部とを含む音波コネクタと;
を含む超音波カテーテル。 - 請求項36の超音波カテーテルであって、前記ねじ部と前記平坦な近位表面の間にさらにスペースを含み、前記平坦な近位表面にはねじが設けられていない超音波カテーテル。
- 超音波カテーテルに超音波変換器を連結するコネクタであって;
カテーテルノブと;
変換器ハウジングを有する変換器であって、前記変換器ハウジングは、スリーブを含むカテーテルカップリングを有する超音波変換器と;
前記超音波変換器と前記カテーテルノブの接続を支持するために前記変換器ハウジングと前記スリーブに結合された輪状のカラーであって、
(i)該カラーが前記スリーブの周りに置かれない第1非支持位置と、
(ii)前記カラーが前記スリーブの一部の周りに置かれる第2支持位置と、
の間で摺動自在である輪状のカラーと;
を含むコネクタ。 - 請求項38のコネクタであって、前記カラーが前記第1位置から前記第2位置まで動くときに前記スリーブに対してますますより強いグリップを与えるように前記スリーブに対して構成されたテーパー付きの内穴を前記カラーが有するコネクタ。
- 請求項38のコネクタであって、前記カラーは、第1位置から第2位置までの移動を容易にするために設けた皿穴を有するコネクタ。
- 請求項38のコネクタであって、前記スリーブは解放端スロットを有するコネクタ。
- 請求項38のコネクタであって、前記スリーブは閉鎖端スロットを有するコネクタ。
- 請求項38のコネクタであって、前記スリーブは複数の閉鎖端スロットと開放端スロットを有するコネクタ。
- 請求項38のコネクタであって、前記スリーブは前記変換器ハウジングに取り付けられているコネクタ。
- 請求項38のカテーテルであって、前記カテーテルが前記変換器ハウジングと結合されるときに前記カラーは前記カテーテルノブにオーバラップするカテーテル。
- 医療の間に超音波伝達部材を冷やす方法であって:
(a)近位端と、遠位先端と、内部を縦方向に通って延伸する内腔と、該内腔を通って縦方向に延伸する超音波伝達部材とを含む超音波カテーテルを経皮的に血管に導入し;
(b)損傷部を持つ血管の必要な治療位置に前記カテーテルの前記遠位先端を位置決めし;
(c)冷却剤の浣注流を前記カテーテルの前記内腔に通すことを開始し;
(d)前記必要な治療位置で超音波離解を開始し;
(e)前記遠位先端における前記冷却剤の温度が50℃を超えないように前記浣注流の流量と圧力を維持する;
ことを含む方法。 - 医療の間に超音波伝達部材を冷却する方法であって:
(a)近位端と、遠位先端と、内部を縦方向に延伸する内腔と、該内腔を通って縦方向に延伸する超音波伝達部材とを含む超音波カテーテルを経皮的に血管に導入し;
(b)損傷部を持つ血管の必要な治療位置に前記カテーテルの前記遠位先端を位置決めし;
(c)冷却剤の浣注流を前記損傷部に隣接した前記遠位先端の外部から前記カテーテルの外及び基部へと前記カテーテルの前記内腔に通すことを容易にするために負圧を生じさせ;
(e)前記遠位先端における前記冷却剤の温度が50℃を超えないように前記浣注流の流量と圧力を維持する;
ことを含む方法。
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Also Published As
Publication number | Publication date |
---|---|
WO2004112888A2 (en) | 2004-12-29 |
WO2004112888A3 (en) | 2006-02-23 |
EP1635903A4 (en) | 2010-07-14 |
EP1635903A2 (en) | 2006-03-22 |
EP2417920A2 (en) | 2012-02-15 |
US20040024393A1 (en) | 2004-02-05 |
US20070161945A1 (en) | 2007-07-12 |
EP2319434A1 (en) | 2011-05-11 |
EP2417920B1 (en) | 2014-12-24 |
EP2417920A3 (en) | 2012-04-25 |
JP4805822B2 (ja) | 2011-11-02 |
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