JP2006232792A - Skin ageing-improving cosmetic - Google Patents
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本発明は肌老化改善化粧料にかかわり、顔に老化のきざしであるしわやたるみが目立つ状態において、その状態を指標とした鑑別により、改善のための主作用成分である理気作用生薬「百合」、理血作用生薬「牡丹皮」、利水作用生薬「芍薬」の各抽出物の共配合に加え、それぞれ適切な肌老化改善効果を増さしめるための生薬成分を選別的に加え、肌老化状態をより的確に改善できる肌老化改善化粧料に関する。 The present invention relates to a skin aging improving cosmetic, and in a state where wrinkles and sagging, which are signs of aging, are conspicuous on the face, discrimination based on the state is used as an active ingredient for improvement. In addition to the co-formulation of each extract of phylogenetic herbal medicine “peony skin” and water-utilizing herbal medicine “glaze”, each herbal aging agent is selectively added to increase the appropriate skin aging improvement effect. The present invention relates to a skin aging improving cosmetic that can improve the condition more accurately.
肌の老化は顔のしみ、しわ、たるみの顕在化によって自他覚され、成年女性に少なからぬ美容上の懸念や精神的ダメージを与えるものだから、その改善努力は古くから絶え間なく続けられてきた。そして現代でも、しみ、しわ、たるみの改善は美容上最重要の課題であり、その改善のための工夫、研究は多くの時間、労力を傾け行われているが、未だほとんどその実を得るに至っていない。 Skin aging is perceived by the manifestation of facial blemishes, wrinkles and sagging, and causes considerable cosmetic concerns and mental damage to adult women, so efforts to improve it have been continually ongoing. . Even in modern times, the improvement of spots, wrinkles and sagging is the most important issue in cosmetics, and the devices and research for the improvement have been carried out with a lot of time and effort. Not in.
しみ、しわ、たるみのうち、しみは皮膚におけるメラニン色素の拡散であり、その拡散には前もっての皮膚の炎症がかかわることから、メラニン生成を抑える物質（ビタミンＣやコウジ酸ほか）や、皮膚炎症を防ぐ物質（グリチルリチンや感光色素ほか）などが化粧料成分として繁用されいささかの効果をあげているが、しわやたるみに対しては、それが年令以上に早く顔にあらわれたり、人によって発現の部位が違っていたりして原因がわからないので、現流通化粧料においては、改善策をほとんどとり得ていない。しわやたるみは皮膚弾力繊維の減衰だから、弾力繊維をこわすコラゲナーゼや、保水物質をこわすヒアルロニダーゼの抑制物質を配合するという現行の方法は、それらの物質の吸収の可能性や、それらが経皮吸収されたとしても、吸収後の動態が全くわからない上、しわ、たるみにおいては、しみにおけるメラニン色素のような具体的標的がみえないので、「原因物質対作用物質」という改善方法を採る従来技術では対応しきれないのである。 Among stains, wrinkles and sagging, stains are the diffusion of melanin pigments in the skin, and this diffusion involves the inflammation of the skin in advance, so substances that suppress melanin production (vitamin C, kojic acid, etc.) and skin inflammation Substances that prevent skin damage (glycyrrhizin, photosensitizing dyes, etc.) are frequently used as cosmetic ingredients, but they have a slight effect on wrinkles and sagging. Since the site of expression is different and the cause is unknown, there are few improvement measures available in the current distribution cosmetics. Since wrinkles and sagging are attenuated skin elastic fibers, the current method of blending collagenase that breaks elastic fibers and hyaluronidase inhibitor that breaks water retention substances has the potential to absorb these substances and absorb them transdermally. However, the kinetics after absorption is not known at all, and in wrinkles and sagging, there is no specific target such as a melanin pigment in the spot. It cannot be handled.
因みにこのような実状のなかで、しわ改善にある程度の効果をあげているものとしてビタミンＡであるレチノイン酸の塗布や、ボツリヌス菌毒素の皮膚注入がある。しかし前者は細胞膜変質のおそれ、後者はその毒素としての本来から、実際には一般が化粧料として継続使用するに与わない。 By the way, among these actual conditions, there are application of retinoic acid, which is vitamin A, and dermal injection of botulinum toxin, which have some effects on wrinkle improvement. However, the former is a risk of cell membrane alteration, and the latter is not originally used as a toxin.
本発明はこのような状況をふまえ、肌老化のあらわれであるしわ、たるみに対し、その改善に理気作用生薬「百合」、理血作用生薬「牡丹皮」、利水作用生薬「芍薬」の各抽出物を共配合した化粧料を以ってし、さらにその効果をたかめるべく、肌老化の状態を弁別し、その状態に適合した生薬抽出物をさらに加え、改善すべき状態に応じた肌老化改善化粧料研究を重ね本発明をなすに至った。 In view of such a situation, the present invention is an improvement of skin aging for wrinkles and sagging. In order to further enhance the effect of the cosmetics co-mixed with the extract, the skin aging state is discriminated, and a crude drug extract suitable for the state is added, and the skin aging according to the state to be improved is added. Research on improved cosmetics was repeated and the present invention was made.
すなわち請求項１にかかわる発明は、生薬分類でいう理気作用生薬と、理血作用生薬と利水作用生薬の各抽出物のセットとしての共配合を特徴とする肌老化改善化粧料に関する。請求項２にかかわる発明は、理気作用生薬が百合（びゃくごう）抽出物であり、理血作用生薬が牡丹皮（ぼたんぴ）抽出物であり、利水作用生薬が芍薬（しゃくやく）抽出物であることを特徴とする請求項１の肌老化改善化粧料に関する。請求項３にかかわる発明は、改善すべき肌老化の状態ごとに、百合、牡丹皮、芍薬各抽出物の共配合に加え、追加配合する生薬抽出物を変化させることを特徴とする請求項１乃至２の肌老化改善化粧料に関する。請求項４にかかわる発明は、改善すべき肌老化の状態を、眼瞼のむくみと、口角のしわと、眉間の表情しわの三つに分類することを特徴とする請求項３の肌老化改善化粧料に関する。請求項５にかかわる発明は、改善すべき肌老化状態が眼瞼のむくみであるとき、百合、牡丹皮、芍薬各抽出物の共配合に加え、利水作用生薬である、ヨクイニン（よくいにん）、蒼述（そうじゅつ）、オウギ（おうぎ）、桑寄生（そうきせい）からなる群から選ばれた一種以上の生薬抽出物を配合したことを特徴とする請求項１乃至３記載の肌老化改善化粧料に関する。請求項６にかかわる発明は、改善すべき肌老化状態が口角のしわであるとき、百合、牡丹皮、芍薬の各抽出物の共配合に加え、理血作用生薬であるサンシシ（さんしし）、黄柏（おうばく）、センキュウ（せんきゅう）、桃仁（とうにん）からなる群から選ばれた一種以上の生薬抽出物を配合したことを特徴とする請求項１乃至３記載の肌老化改善化粧料に関する。請求項７に関する発明は、改善すべき肌老化状態が眉間の表情じわであるとき、百合、牡丹皮、芍薬の各抽出物の共配合に加え、理気作用生薬である、香附子（こうぶし）、鳥薬（うやく）、葛根（かっこん）、サンソウニン（さんそうにん）からなる群から選ばれた一種以上の生薬抽出物を配合したことを特徴とする請求項１乃至３記載の肌老化改善化粧料に関する。 That is, the invention according to claim 1 relates to a skin aging-improving cosmetic characterized by co-formulation as a set of extracts of a physicating crude drug and a physiologic acting crude drug and a hydrating drug. In the invention according to claim 2, the physicating herb is a lily extract, the physiologic herb is a peony skin extract, and the water-utilizing herb is a shakuyaku extract. The skin aging-improving cosmetic composition according to claim 1. The invention according to claim 3 is characterized in that, depending on the state of skin aging to be improved, in addition to the co-formulation of the lily, peony skin, and glaze extracts, the herbal extract to be additionally formulated is changed. The present invention relates to skin aging improving cosmetics 2 to 2. The invention according to claim 4 classifies the state of skin aging to be improved into three categories: eyelid swelling, mouth corner wrinkles, and expression wrinkles between eyebrows. Regarding fees. In the invention according to claim 5, when the skin aging state to be improved is swelling of the eyelids, in addition to the co-formulation of each extract of lily, peony skin, and glaze, Yokuinin, which is a water-utilizing herbal medicine 4. One or more herbal extracts selected from the group consisting of: Sojutsu, Ogi, and Mulberry parasites are blended. It relates to a skin aging improving cosmetic. In the invention according to claim 6, when the skin aging state to be improved is wrinkle of the mouth corner, in addition to the co-formulation of each extract of lily, peony skin, and glaze, Sanshishi 4. A cosmetic composition for improving skin aging according to any one of claims 1 to 3, characterized in that it contains one or more herbal extracts selected from the group consisting of corn, jaundice, senkyu and tonin. Regarding fees. In the invention relating to claim 7, when the skin aging state to be improved is a facial expression between the eyebrows, in addition to the co-formulation of the lily, peony skin and glaze extracts, 4. One or more herbal extracts selected from the group consisting of sushi, bird medicine, kakkon, sansonin, and the like. It relates to a skin aging improving cosmetic.
本発明における肌老化改善化粧料は、肌老化改善のための作用成分として先ず理気作用生薬として百合、理血作用生薬として牡丹皮、利水作用生薬として芍薬の各抽出物を選んで共配合し、さらに肌老化の目立つ状態を指標とした選択で、眼瞼にむくみの目立つ状態
本発明における肌老化改善化粧料は、しわやたるみの改善において、コラゲナーゼ阻害剤やヒアルロニダーゼ阻害剤など、しわやたるみの増減との関連がｉｎ ｖｉｖｏにおいてはっきりしないものの配合を離れ、肌状態を体調のあらわれと捉え、体調バランスに資するものとして、理気作用生薬「百合」、理血作用生薬「牡丹皮」、利水作用生薬「芍薬」の各抽出物を化粧料に共配合し、さらに肌老化の目立つ状態を指標とした選択で、もっともよくその肌老化状態改善を助ける物質を併せ配合し、それぞれの状態の肌老化改善に充てることを特徴としている。 The skin aging-improving cosmetic composition of the present invention leaves a combination of collagenase inhibitors and hyaluronidase inhibitors, such as collagenase inhibitors and hyaluronidase inhibitors, that are not clearly related in vivo to improve wrinkles and sagging, and to improve skin condition. It is considered that it appears and contributes to the balance of physical condition, the extracts of the liquor herbal medicine `` Yuri '', the physiologic herbal medicine `` peony skin '', and the water-use herbal medicine `` glaze '' are co-blended with cosmetics, and further skin aging It is characterized by being selected with a conspicuous state as an index, and most often containing substances that help improve the skin aging state, and is used to improve skin aging in each state.
この発明において、先ず理気作用生薬「百合」、理血作用生薬「牡丹皮」、利水作用生薬「芍薬」の各抽出物を化粧料に共配合する目的は、肌の状態は体調の反映であり、体調は精神神経系の働き（漢方医学の「気」にあたる）、血液循環系の働き（漢方医学の「血」にあたる）、水電解質代謝系の働き（漢方医学の「水」にあたる）のバランスにより保たれるものだから、精神神経系の働き、血液循環系の働き、水電解質代謝系の働きをそれぞれなめらかにする百合、牡丹皮、芍薬の各抽出物を共配合して、肌の皮膚機能の滞りを防いで、肌老化状態を改善する。さらにまた、この体調のバランスにいびつさがあれば、それはたちまち肌状態にあらわれるから、精神神経系の働き、血液循環系の働き、水電解質代謝系の働きのうち、滞りが突出するものがあれば肌老化の目立つ部位を指標にそれを知り、それが精神神経系の滞りのあらわれなら別に理気作用生薬を選び、それが血液循環系の滞りのあらわれなら、別に理血作用生薬を選び、またそれが水電解質代謝系の滞りなら、別に利水作用生薬を選んで、おのおのその抽出物を先の化粧料に追加して配合し、効果をよりたしかにする。因みに精神神経系の滞りは眉間にあらわれる表情じわのほか、口苦、いらいら感、のぼせやすさなどのことで知り、血液循環系の滞りは口角のしわのほか、化粧映えしない、唇の色がくらい、静脈が浮いてみえるなどのことで知り、水電解質代謝系の滞りは眼瞼のむくみのほか、汗の多さ、軟便の傾向、口舌の歯痕などのことでも知ることができる。 In this invention, first, the purpose of co-mixing each extract of the ritual herbal medicine "Yuri", the physiologic herbal medicine "peony skin", and the irrigating herbal medicine "glaze" into the cosmetic is to reflect the physical condition of the skin. Yes, the physical condition is the function of the neuropsychiatric system (corresponds to “Ki” in Kampo medicine), the function of the blood circulatory system (corresponds to “blood” in Kampo medicine), the function of the water electrolyte metabolism system (corresponds to “Water” in Kampo medicine) Because it is maintained by balance, it can coexist with lily, peony skin, and glaze extracts that smooth the functions of the neuropsychiatric system, blood circulatory system, and water electrolyte metabolic system. Prevents functional stagnation and improves skin aging. Furthermore, if there is an annoyance in the balance of this physical condition, it immediately appears in the skin state, so there may be a stagnation among the functions of the neuropsychiatric system, the blood circulation system, and the water electrolyte metabolism system. For example, if it shows a stagnation of the neuropsychiatric system, select another psychiatric crude drug, and if it shows a stagnation of the blood circulatory system, select another physiologic herbal medicine, Also, if it is a stagnation of the water electrolyte metabolism system, select a diuretic herbal medicine and add each extract to the above cosmetics to make it more effective. By the way, the mental nervous system stagnation is known not only with facial expressions appearing between the eyebrows, but also with bitterness, irritability, ease of hotness, etc. However, the stagnation of the water electrolyte metabolism system can be found not only by swelling of the eyelids, but also by sweatiness, tenderness of stools, and dental marks on the tongue.
この発明で用いる生薬のうち、百合（Ｌｉｌｉｕｍ ｂｒｏｗｎｉｉ Ｆ．Ｂ．Ｂｒｏｗｎ ｖａｒｃｏｌｃｈｅｓｔｅｒｉＷｉｌｓ）はユリ科百合の根、香附子（Ｃｙｐｅｒｕｓ ｒｏｔｕｎｄｕｓ Ｌ）はカヤツリグサ科ハマスゲの根茎、烏薬（Ｌｉｎｄｅｒａ ｓｔｒｙｃｈｎｉｆｏｒｉａ Ｆ．Ｖｉｌｌ）はクスノキ科テンダイウヤクの根、葛根（Ｐｕｅｒａｒｉａ ｐｓｅｕｄｏ−ｈｉｒｓｕｔａ Ｔａｎｇ ｅｔ Ｗａｎｇ）はマメ科クズの塊根、サンソウニン（Ｚｉｚｙｐｈｕｓ ｓｐｉｎｏｓｕｓ Ｈｕ）はクロウメモドキ科サネブトナツメの成熟種子の何れも乾燥物で薬理的には顕部や皮膚、粘膜からの発散作用により精神神経系の疎通をはかるに用いられる。 Among the herbal medicines used in the present invention, Lily browni FB Brown varcolchesteri Wils is the root of the lily family lily, Cyperus rotundus L is the rhizome of the cyperaceae Hamasuge, and the glaze (Lindera frychryl. The roots of the camphoraceae (Pueraria pseudou-hirsuta Tang et Wang) are the roots of the leguminous kudu, and the pharmacological seeds of the zebrafish (Zizyphus spinosus Hu) are the dried pharmacology and the mature seeds of the black-tailed crabs. It is used to communicate with the neuropsychiatric system by divergent action from the mucous membrane.
この発明で用いる生薬のうち牡丹皮は牡丹（Ｐａｅｏｎｉａ ｓｕｆｆｒｕｔｉｃｏｓａ Ａｎｄｒ）ボタン科ボタンの根皮、サンシシはシシ（Ｇａｒｄｅｎｉａ ｊａｓｍｉｎｏｉｄｅｓ Ｅｌｌｉｓ）アカネ科コリンクチナシの成熟種子、黄柏（Ｐｈｅｌｌｏｄｅｎｄｒｏｎ ａｍｕｒｅｎｓ Ｒｕｐｒ）はミカン科キハダのコルク層を除いた樹皮、センキュウ（Ｌｉｇｕｓｔｉｃｕｍ ｗａｌｌｉｃｈｉ Ｆｒａｎｃｈ）はセリ科センキュウの根茎、桃仁（Ｐｒｕｍｕｓ ｐｅｒｓｉｃａ（Ｌ）Ｂａｔｓｃｈ）はバラ科モモの成熟種子の何れも乾燥物で、薬理的には血液循環系の流状を円滑する目的で、うっ血、出血、充血、内出血に用いられる。 Of the herbal medicines used in this invention, the peony skin is the root bark of the peony (Paeonia saffruticosa Andr) button family button, the sanshishi is the shrimp (Gardenia jasminoides Ellis), the mature seed of the Rubiaceae corinthaceae, and the Phelliendrona urhamada family. The bark excluding the cork layer, senkyu (Ligusticum wallici Franc) is the rhizome of the sericaceae nematode, and Prunus persica (L) Batsch is a dry product of all mature seeds of the rosaceae peach, pharmacologically the blood circulation system It is used for stasis, bleeding, hyperemia, and internal bleeding in order to smooth the flow of blood.
次いでこの発明で用いられる生薬のうち芍薬（Ｐａｅｏｎｉａ ｌａｃｔｉｆｌｏｒａ Ｐａｌｌ）はボタン科シャクヤクの根、ヨクイニン（Ｃｏｉｘ Ｌａｃｈｒｙｍａ−ｊｏｂｉ Ｌ）はイネ科ハトムギの成熟種子、ソウジュツ（Ａｔｒａｃｔｙｌｏｄｅｓ ｌａｎｓｅａ （Ｔ−ｈｕｍｂ）ＤＣ）はキク科ホソバオケラの根茎、オウギ（Ａｓｔｒａｇａｌｕｓ ｍｅｎｂｒａｎａｃｅｕｓ Ｂｇｅ）はマメ科キバナオウギの根、桑寄生（Ｌｏｒａｎｔｈｕｓ ｐａｒａｃｉｔｉｃｈｓ（Ｌ）Ｍｅｒｒ）はヤドリギ科ソウキセイの枝葉の何れも乾燥物で、薬理的には気管、呼吸器、泌尿器、皮膚などを主とした身体各部の水電解質代謝調節に用いられる。 Next, among the crude drugs used in the present invention, the glaze (Paeonia lactiflora Pall) is the root of the peony peony, the Yokuinin (Coix Lachryma-jobi L) is the mature seed of the cereal pearl barley, and the tactile lancea (T-humb) Rhizome of Asteraceae, Astragalus menbranaceus Bge is a root of the leguminous tree, and a mulberry parasite (Loranthus paralytics (L) Merr) is a dry product of phytopathologically, trachea. It is used to regulate water electrolyte metabolism in various parts of the body, mainly the urinary organs and skin.
本発明において弁別する肌老化の目立つ状態のうち、眼瞼のむくみは、体の水電解質代謝の乱れが、体表で早期に観察できる唯一の状態で、毎日の化粧に鏡をみる女性においては、わかりやすい標識である。その対応に生薬を用いる漢方医学は、この水電解質代謝の乱れを、体における水分量の多い少ないでなく、体内の水分分布異常、すなわち病因となる水の偏在として捉え、現代医学でもこの考えは踏襲されはじめている。利水作用生薬は水電解質代謝の乱れに対し、体内偏在の水分を平均化し（利水作用）、眼瞼のむくみや汗の多さ、軟便の傾向、口舌の歯痕などを緩和する。因みに眼瞼は動きの激しさに便利なように皮膚が顔面で最も薄く、僅かの水分貯留もむくみとなってあらわれやすい。次に肌老化の目立つ状態のうち、口角のしわは、やはり動きが激しく新陳代謝が早い口周辺の筋や皮膚への循環不足がかかわり、とくに消化器系のうっ血、充血、失血などで顕在化しやすい。理血作用生薬は血行のうっ滞を緩和し、血液の流動性をたかめ（理血作用）、口角のしわや、静脈が浮いてみえるなどを目立たなくし、唇の色を明るくし化粧映えをよくする。次いで肌老化の目立つ状態のうち、眉間の表情じわは、「眉をしかめる」というものいいからもわかるように感情の波立ちによってあらわれ、精神神経系の興奮しやすく抑制ききにくい性格者に多発しだんだん固定化し額にしわを残していく。理気作用生薬は自律神経系の緊張傾向を緩和するもので（理気作用）眉間の表情しわをあらわれにくくし、緊張による口の渇き、苦さをやわらげ、いらいら感やのぼせを鎮めたりする。 Among the conspicuous states of skin aging that are distinguished in the present invention, the swelling of the eyelids is the only state in which disturbance of water electrolyte metabolism of the body can be observed early on the body surface, and in a woman who looks at the mirror in daily makeup, This is an easy-to-understand sign. Kampo medicine, which uses herbal medicine to deal with this problem, sees this disturbance of water electrolyte metabolism as an abnormal distribution of water in the body, that is, an uneven distribution of water in the body. Being followed. The water-utilizing crude drug averages unevenly distributed water in the water electrolyte metabolism disorder (water-utilizing action), and relieves swelling of the eyelids, sweatiness, tenderness of loose stools, and dental marks on the tongue. By the way, the eyelid has the thinnest skin on the face so that it is convenient for the intensity of movement, and a small amount of moisture is easily swollen. Next, among the conspicuous conditions of skin aging, wrinkles in the corners of the mouth are also apt to be manifested due to lack of circulation to the muscles and skin around the mouth, which are rapidly moving and rapidly metabolized, and are particularly congestive, congestive, and bloodless. . Herbal remedies alleviate blood stasis, increase blood fluidity (physical effect), make wrinkles in the corners of the mouth, and veins appear to be inconspicuous, brighten the lips and improve makeup To do. Next, among the conspicuous states of skin aging, the facial expression between the eyebrows appears as a result of emotional pulsation, as seen by the fact that “broken the eyebrows”. Gradually fix and leave wrinkles on the forehead. Herbal medicines relieve tension tendency in the autonomic nervous system (reaching action), make it difficult to show facial wrinkles between the eyebrows, relieve thirst and bitterness due to tension, and relieve irritation and hot flashes.
本発明の肌老化改善化粧料においては、上記理気作用生薬、百合、香附子、烏薬、葛根、サンソウニン、また理血作用生薬、牡丹皮、サンシシ、黄柏、センキュウ、桃仁、また利水作用生薬、芍薬、ヨクイニン、ソウジュツ、オウギ、桑寄生などの抽出物の配合に加え、通常化粧料に用いられる各種原料、成分を適宣任意に用いて剤型を整えることも差し支えない。それら原料、成分にはとくに限定あるものではないが、通常の外用剤（化粧品、医薬品、医薬部外品など）に用いられる公知の原料や成分、例えば油脂類、ロウ類、炭化水素、脂肪酸類、アルコール類、多価アルコール類、エステル類、高分子化合物、界面活性剤、酸化防止剤、金属封鎖剤、ＰＨ調整剤、合成有機塩類、保湿剤、香料、ビタミン類、酵素類、有機薬品類、無機薬品類、動物植物抽出成分類などである。 In the skin aging-improving cosmetic composition of the present invention, the above-mentioned herbal medicine, lily, katsuki, glaze, kudzu root, sansonin, phylogenetic herbal medicine, peony skin, sanshishi, jaundice, nematode, peach seed, and water-use herbal medicine In addition to blending extracts such as glaze, Yokuinin, Sugitsu, Ogi, Mulberry parasite, etc., various ingredients and ingredients usually used in cosmetics may be arbitrarily used arbitrarily to prepare the dosage form. These raw materials and components are not particularly limited, but known raw materials and components used for ordinary external preparations (cosmetics, pharmaceuticals, quasi drugs, etc.), such as fats and oils, waxes, hydrocarbons, fatty acids , Alcohols, polyhydric alcohols, esters, polymer compounds, surfactants, antioxidants, sequestering agents, pH adjusters, synthetic organic salts, moisturizers, fragrances, vitamins, enzymes, organic chemicals , Inorganic chemicals, animal plant extracts and the like.
また本発明の肌老化改善化粧料は、化粧料としていかなる剤型をとるもよしとするが、例えば、クリーム、乳液、ローション、ジェルローション、口紅、リップクリームなどの剤型を好適とする。 The cosmetic composition for improving skin aging according to the present invention may take any dosage form as a cosmetic composition, but suitable dosage forms such as cream, emulsion, lotion, gel lotion, lipstick and lip balm are suitable.
次に本発明の肌老化改善化粧料への上記生薬抽出物配合量についていえば、一生薬抽出物について０．０５〜１．５重量％の範囲、好ましくは０．１〜１．０％を適当とし、生薬抽出物としては日局、粧原基（配規）、食添など収載のものを好適とする。 Next, regarding the blending amount of the above-mentioned herbal medicine in the skin aging improving cosmetic of the present invention, the range of 0.05 to 1.5% by weight, preferably 0.1 to 1.0%, of the herbal medicine extract. As the herbal medicine extract, those listed in Japanese Pharmacopoeia, Jeongwon (regulation), food additives, etc. are suitable.
以下、本発明を実施例により説明する。但し本発明は以下の実施例に何らの限定を受けるものではない。 Hereinafter, the present invention will be described by way of examples. However, the present invention is not limited to the following examples.
表１の組成によりＡまたはＢまたはＣのジェルローションをつくる。 Make a gel lotion of A, B or C according to the composition in Table 1.
グリセリン ５．０（重量％、以下同じ）
プロピレングリコール ４．０
オイルアルコール ０．１
ポリオキシエチレンソルビタンモノラウリン酸エステル １．５
（２０Ｅ，０）
ポリオキシエチレンラウリルエ−テル（２０Ｅ，０） ０．５
エタノール １０．０
香料 ０．１
品質保持（防腐、酸化防止）剤 適量
百合抽出物 ０．３
牡丹皮抽出物 ０．３
芍薬抽出物 ０．３
葛根抽出物（理気作用生薬） ０．３
精製水 残量
合計，１００．０Glycerin 5.0 (wt%, the same applies hereinafter)
Propylene glycol 4.0
Oil alcohol 0.1
Polyoxyethylene sorbitan monolaurate 1.5
(20E, 0)
Polyoxyethylene lauryl ether (20E, 0) 0.5
Ethanol 10.0
Fragrance 0.1
Quality preservation (preservation, anti-oxidation) agent Yuri extract 0.3
Peony skin extract 0.3
Glaze extract 0.3
Kakkon Extract (Rikiki Herbal Medicine) 0.3
Purified water remaining
Total, 100.0
表１の組成化粧料を実施例１のＡタイプジェルローションとし、組成中の葛根抽出物を理血作用生薬である黄柏抽出物に置きかえたものを実施例１のＢタイプジェルローションとし、同じ表１組成中の葛根抽出物を利水作用生薬であるオウギ抽出物に置きかえたものを実施例１のＣタイプジェルローションとした。 The composition of Table 1 was designated as A-type gel lotion of Example 1, and the composition obtained by replacing the kuzu root extract in the composition with jaundice extract as a physico-acting crude drug was designated as B-type gel lotion of Example 1, and the same table A C-type gel lotion of Example 1 was obtained by replacing the Kakkon extract in one composition with the ogi extract which is a water-utilizing crude drug.
（試験例）
上記実施例１ジェルローションによる試験例を示す。
２７〜４６才の健康女性（肌にも皮膚疾患等のない）１９人について、その体調を表２によるチェックで弁別し、ａの精神神経系項目に該当多いもの６人にＡタイプジェルローションを、ｂの血液循環系項目に該当多いもの５人にＢタイプジェルローションを、ｃの水電解質代謝系項目に該当多いもの８人にＣタイプジェルローションを、それぞれ４週間継続して毎就寝前、洗顔後の顔に塗布せしめ、試験期間前後の肌状態を、ａについては表３の基準により、ｂについては表４の基準により、ｃについては表５の基準により比較した。評価は２段階以上の改善を有効、１段階の改善をやや有効、その他を無効とした。結果を表６、表７、表８に示す。(Test example)
The test example by the said Example 1 gel lotion is shown.
About 19 healthy women aged 27 to 46 (no skin disease etc. on skin), the physical condition was discriminated by the check according to Table 2, and A type gel lotion was given to 6 people who often correspond to the psychoneurological item of a. B type gel lotion for 5 people who have a lot of blood circulation items in b, C type gel lotion for 8 people who have a lot of water electrolyte metabolism items in c, 4 weeks each before going to bed, It was applied to the face after washing, and the skin conditions before and after the test period were compared according to the criteria in Table 3 for a, according to the criteria in Table 4 for b, and according to the criteria in Table 5 for c. In the evaluation, two or more stages of improvement were effective, one stage of improvement was somewhat effective, and others were disabled. The results are shown in Table 6, Table 7, and Table 8.
なお試験期間中、Ａタイプ、Ｂタイプ、Ｃタイプのジェルローション塗布前の洗顔は、被験の１９人全て、同一処方の洗顔乳液を用いるようにした。また本試験期間中、及び試験後１週間のあいだに、皮膚トラブルを発生したものはいなかった。 During the test period, face washing before applying A type, B type, and C type gel lotions was carried out using all of the 19 test subjects with the same prescription. In addition, no skin trouble occurred during the test period and during the 1 week after the test.
被験者の体質弁別チェック表、（ａ、ｂ、ｃについて各該当項目を数える。）
ａ．精神神経系の項目、（気の滞り）
夜間熟睡できない。
便通がすっきりしない。
おなかが張る。
何となく胸ふさがる感がある。
化粧が楽しくない。
ｂ．血液循環系の項目、（血の滞り）
唇の色がわるい。
メイクアップが伸びない（化粧のりが悪い）。
何となく怒りっぽい。
物音にびっくりしやすい。
肩こりは左のことが多い。
ｃ．水電解質代謝の項目、（水の滞り）
動くのがおっくう。
何となく楽しめない。
かがむのが大儀。
舌のふちに歯痕のぎざぎざがみえる。
肩こりは右のことが多い。Subject's constitution discrimination check table, (count each applicable item for a, b, c)
a. Psychiatric and nervous system items, (dullness)
I can't sleep at night.
The bowel movement is not clean.
I'm hungry.
There is a feeling that somehow my chest is closed.
Makeup is not fun.
b. Blood circulatory system items (blood stagnation)
The color of the lips is bad.
Make-up does not grow (bad makeup).
Somehow angry.
It is easy to be surprised by the noise.
The stiff shoulders are often left.
c. Item of water electrolyte metabolism, (stagnation of water)
It ’s great to move.
I can't enjoy it.
It is great to bend.
Jagged teeth appear on the edge of the tongue.
Stiff shoulders are often on the right.
Ａタイプジェルローション使用者の肌状態基準
１． いつも眉間に立てじわ、額に横じわがある。
２． 感情が動くとよく眉間に立てじわがあらわれる、額の横じわはいつもある。
３． 時々無意識に立てじわ、横じわがあらわれることがある。
４． 表情によって横じわがあらわれるがすぐ元に戻る、立てじわがあまりあらわれない。
５． 眉間の立てじわや額の横じわはあまり目立たない。Skin condition criteria for A type gel lotion users There are always wrinkles between the eyebrows, and there are wrinkles on the forehead.
2. There are always wrinkles on the forehead that often appear between the eyebrows when emotions move.
3. Occasionally, the wrinkles sometimes appear unconsciously.
4). A horizontal wrinkle appears depending on the expression, but it quickly returns to its original state.
5). The lines between the eyebrows and the side lines of the forehead are not very noticeable.
Ｂタイプジェルローション使用者の肌状態基準
１． 普通でも鼻翼、口角のしわがくっきりしている。
２． 表情の動きに伴って鼻翼、口角のしわが目立ってみえる。
３． 表情の動きに伴って鼻翼のしわは目立つが、口角のしわは目立たない。
４． 鼻翼から口にかけてのしわがうすくみえるだけ。
５． 鼻や口のまわりのしわは目立たない。Skin condition criteria for B-type gel lotion users Ordinary wrinkles on the nose wings and mouth corners are clear.
2. The wrinkles of the nose wings and mouth corners are conspicuous as the facial expression moves.
3. Wrinkles on the nose wings are noticeable as the facial expression moves, but wrinkles on the corners of the mouth are not.
4). Just wrinkles from nose wing to mouth.
5). Wrinkles around the nose and mouth are inconspicuous.
Ｃタイプジェルローション使用者の肌状態基準
１． 瞼全体がはれぼったく、下瞼のたるみが目立つ。
２． 上瞼がはれぼったく、下瞼の皮膚は少し波打っている。
３． 上瞼のはれぼったさはあまり目立たないが下瞼はややくぼんでいる。
４． 瞼にはれぼったさは目立たないが、下瞼内角にしわがみえる。
５． 瞼にはれぼったさはなく、下瞼内角のしわも目立たない。Skin condition criteria for C type gel lotion users The whole heel is spilled and the slack of the lower heel is conspicuous.
2. The upper heel is peeled off, and the lower heel skin is slightly wavy.
3. The swell of the upper arm is not very noticeable, but the lower arm is slightly depressed.
4). The spear is not noticeable, but wrinkles are seen in the inner corner of the lower arm.
5). There is no sag in the heel, and the wrinkles in the lower heel are not noticeable.
以下に本発明にかかわる肌老化改善化粧料の処方例を示す。 The prescription example of the skin aging improvement cosmetics concerning this invention is shown below.
（処方例１）クリーム
グリセリルモノステアレート ２．０（重量％，以下同じ）
ポリオキシエチレン（２０）ソルビタンモノステアレート ３．０
セタノール ２．０
スクアラン １０．０
２−エチルヘキサングリセリル １０．０
グリセリン ５．０
パラベン ０．１
百合抽出物 ０．３
牡丹皮抽出物 ０．３
芍薬抽出物 ０．３
葛根（または黄柏またはオウギ） ０．３
精製水 残量
合計 １００．０(Formulation Example 1) Cream glyceryl monostearate 2.0 (% by weight, the same applies hereinafter)
Polyoxyethylene (20) sorbitan monostearate 3.0
Cetanol 2.0
Squalane 10.0
2-Ethylhexaneglyceryl 10.0
Glycerin 5.0
Paraben 0.1
Lily extract 0.3
Peony skin extract 0.3
Glaze extract 0.3
Kudzu (or jaundice or ogi) 0.3
Purified water remaining
Total 100.0
Claims (7)
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| JP2005080412A JP2006232792A (en) | 2005-02-21 | 2005-02-21 | Skin ageing-improving cosmetic |
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| JP2005080412A JP2006232792A (en) | 2005-02-21 | 2005-02-21 | Skin ageing-improving cosmetic |
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| WO2009061431A3 (en) * | 2007-11-08 | 2009-07-23 | Aciex Inc | Compositions for the treatment and prevention of eyelid swelling comprising an osmotically active ingredient and a vasoconstrictor |
| JP2012509255A (en) * | 2008-11-19 | 2012-04-19 | 株式會社アモーレパシフィック | Antioxidant cosmetic composition containing smoked peony, jade bamboo or lily extract |
| US8685439B2 (en) | 2006-04-26 | 2014-04-01 | Aciex Therapeutics, Inc. | Method for the treatment and prevention of eyelid swelling |
| CN103989601A (en) * | 2014-05-29 | 2014-08-20 | 皖南医学院 | Shining, moisturizing and skin-finishing cream and preparation method thereof |
| CN108815064A (en) * | 2018-09-28 | 2018-11-16 | 合肥满地金农业科技有限公司 | A kind of natural tree peony nourishing lipstick |
| JP2018184349A (en) * | 2017-04-24 | 2018-11-22 | ポーラ化成工業株式会社 | Eyelid skin surface impression improver and screening method therefor |
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2005
- 2005-02-21 JP JP2005080412A patent/JP2006232792A/en active Pending
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|---|---|---|---|---|
| US8685439B2 (en) | 2006-04-26 | 2014-04-01 | Aciex Therapeutics, Inc. | Method for the treatment and prevention of eyelid swelling |
| WO2009061431A3 (en) * | 2007-11-08 | 2009-07-23 | Aciex Inc | Compositions for the treatment and prevention of eyelid swelling comprising an osmotically active ingredient and a vasoconstrictor |
| JP2012509255A (en) * | 2008-11-19 | 2012-04-19 | 株式會社アモーレパシフィック | Antioxidant cosmetic composition containing smoked peony, jade bamboo or lily extract |
| CN103989601A (en) * | 2014-05-29 | 2014-08-20 | 皖南医学院 | Shining, moisturizing and skin-finishing cream and preparation method thereof |
| JP2018184349A (en) * | 2017-04-24 | 2018-11-22 | ポーラ化成工業株式会社 | Eyelid skin surface impression improver and screening method therefor |
| CN108815064A (en) * | 2018-09-28 | 2018-11-16 | 合肥满地金农业科技有限公司 | A kind of natural tree peony nourishing lipstick |
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