JP2006143623A - ダイフラクトースアンハイドライド含有経口組成物 - Google Patents
ダイフラクトースアンハイドライド含有経口組成物 Download PDFInfo
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- JP2006143623A JP2006143623A JP2004333663A JP2004333663A JP2006143623A JP 2006143623 A JP2006143623 A JP 2006143623A JP 2004333663 A JP2004333663 A JP 2004333663A JP 2004333663 A JP2004333663 A JP 2004333663A JP 2006143623 A JP2006143623 A JP 2006143623A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
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- Mycology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
- Saccharide Compounds (AREA)
- Feed For Specific Animals (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pyrane Compounds (AREA)
- Cosmetics (AREA)
Abstract
【課題】腸内細菌のエクオール産生能を活性化する。
【解決手段】ダイフラクトース アンハイドライドを有効成分として含有する腸内細菌によるエクオール産生増強用経口組成物。
【選択図面】 なし
Description
一方、ダイフラクトースアンハイドライド(以下DFAと記す)についてはビフィズス菌増殖作用を有すること(特許文献1:特公平3−5788号公報)やカルシウム吸収量を増やすこと(特許文献2:特開平11−43438号公報)、利尿作用をもつこと(特許文献3:特開2003−321371号公報)が知られていたが、エクオールの産生増強作用は知られていなかった。
(1)ダイフラクトース アンハイドライドを有効成分として含有することを特徴とする腸内細菌によるエクオール産生増強用経口組成物。
(2)ダイフラクトース アンハイドライドとダイゼイン及び/又はその誘導体を含有することを特徴とする腸内細菌によるエクオール産生増強用経口組成物。
(3)(1)又は(2)に記載された腸内細菌によるエクオール産生増強用経口組成物を含有する医薬又は飲食品。
(4)(1)又は(2)に記載された腸内細菌によるエクオール産生増強用組成物を含有するペット動物用医薬又はペット動物用飼料。
その使用量は症状、年令、体重、剤形によって異なるが、通常は、成人に対して、経口投与の場合に1日当たり、体重1kg当たり0.5〜2000mg、好ましくは1〜1000mgの範囲で投与するのがよい。
Wistar-ST系雄ラット(6週齢)27匹を3日間固形飼料で予備飼育した後、体重層別法により各群n=9で3群に分け、それぞれにイソフラボン40%含有食品を0.25%含有した基本飼料(Basal diet群)、基本飼料のスクロースを全体の3%DFAIIIで置換した飼料(DFAIII群)、基本飼料のスクロースを全体の3%フラクトオリゴ糖で置換した飼料(FOS群)を与えて20日間飼育した。20日目に尾静脈より採血を行い、HPLC-UV法で血漿中のエクオール(Equol)濃度を測定した。
この結果から明らかなように、DFAの摂取により、DFAによる血漿中のエクオール(Equol)濃度の上昇が認められた。
Claims (4)
- ダイフラクトース アンハイドライドを有効成分として含有することを特徴とする腸内細菌によるエクオール産生増強用経口組成物。
- ダイフラクトース アンハイドライドとダイゼイン及び/又はその誘導体を含有することを特徴とする腸内細菌によるエクオール産生増強用経口組成物。
- 請求項1又は請求項2に記載された腸内細菌によるエクオール産生増強用経口組成物を含有する医薬又は飲食品。
- 請求項1又は請求項2に記載された腸内細菌によるエクオール産生増強用経口組成物を含有するペット動物用医薬又はペット動物用飼料。
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004333663A JP4723849B2 (ja) | 2004-11-17 | 2004-11-17 | ダイフラクトースアンハイドライド含有経口組成物 |
AT05799109T ATE526835T1 (de) | 2004-11-17 | 2005-10-25 | Orale zusammensetzung enthaltend difructoseanhydrid |
CN2005800390919A CN101056644B (zh) | 2004-11-17 | 2005-10-25 | 含有双果糖酐的经口组合物 |
EP05799109A EP1825856B1 (en) | 2004-11-17 | 2005-10-25 | Oral composition containing difructose anhydride |
US11/719,239 US8530446B2 (en) | 2004-11-17 | 2005-10-25 | Oral composition containing difructose anhydride |
PCT/JP2005/019597 WO2006054429A1 (ja) | 2004-11-17 | 2005-10-25 | ダイフラクトース アンハイドライド含有経口組成物 |
HK08100975.1A HK1107266A1 (en) | 2004-11-17 | 2008-01-24 | Oral composition containing difructose anhydride |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004333663A JP4723849B2 (ja) | 2004-11-17 | 2004-11-17 | ダイフラクトースアンハイドライド含有経口組成物 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2006143623A true JP2006143623A (ja) | 2006-06-08 |
JP4723849B2 JP4723849B2 (ja) | 2011-07-13 |
Family
ID=36406974
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2004333663A Active JP4723849B2 (ja) | 2004-11-17 | 2004-11-17 | ダイフラクトースアンハイドライド含有経口組成物 |
Country Status (7)
Country | Link |
---|---|
US (1) | US8530446B2 (ja) |
EP (1) | EP1825856B1 (ja) |
JP (1) | JP4723849B2 (ja) |
CN (1) | CN101056644B (ja) |
AT (1) | ATE526835T1 (ja) |
HK (1) | HK1107266A1 (ja) |
WO (1) | WO2006054429A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2036916A1 (en) * | 2006-06-20 | 2009-03-18 | Unitika, Ltd. | Composition for promoting the production of equol |
WO2020004568A1 (ja) | 2018-06-28 | 2020-01-02 | アサヒグループホールディングス株式会社 | エクオール産生促進剤およびそれを含むエクオール産生促進用食品または飲料組成物 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006193459A (ja) * | 2005-01-12 | 2006-07-27 | Fancl Corp | 血中コレステロール低下用経口組成物 |
JP5285852B2 (ja) * | 2006-12-28 | 2013-09-11 | 株式会社ファンケル | Dfaiiiの製造方法及びdfaiii高含有植物エキス |
JP5631862B2 (ja) | 2009-02-25 | 2014-11-26 | 株式会社ヤクルト本社 | エコール産生細菌及びその利用 |
KR101307947B1 (ko) | 2011-11-30 | 2013-09-12 | 씨제이제일제당 (주) | 싸이코스를 유효성분으로 하는 에쿠올 농도 상승제 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63269962A (ja) * | 1987-04-28 | 1988-11-08 | Natl Food Res Inst | 食品素材 |
JPH1143438A (ja) * | 1997-07-29 | 1999-02-16 | Nippon Beet Sugar Mfg Co Ltd | カルシウム吸収亢進組成物 |
WO1999007392A1 (fr) * | 1997-08-08 | 1999-02-18 | Otsuka Pharmaceutical Co., Ltd. | Compositions contenant de l'isoflavone |
JP2000204042A (ja) * | 1999-01-13 | 2000-07-25 | Nippon Mitsubishi Oil Corp | 環状オリゴ糖 |
WO2003090759A1 (fr) * | 2002-04-26 | 2003-11-06 | Fancl Corporation | Composition contenant du difructose anhydride et utilisation de celle-ci |
JP2004161619A (ja) * | 2002-11-11 | 2004-06-10 | Fancl Corp | 骨形成促進組成物 |
WO2004078989A1 (ja) * | 2003-03-05 | 2004-09-16 | Nippon Beet Sugar Mfg. Co., Ltd. | ジフルクトース・ジアンヒドリドiiiの精製方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2136233C (en) * | 1992-05-19 | 2004-03-30 | Graham Edmund Kelly | Health supplements containing phyto-oestrogens, analogues or metabolites thereof |
US5925190A (en) | 1995-06-06 | 1999-07-20 | The University Of Montana | Production of fructose dianhydride products from inulin |
EP1060744B1 (en) | 1998-03-06 | 2005-11-23 | Meiji Seika Kaisha, Ltd. | Preventives/remedies for osteoporosis |
EP1214893A1 (en) | 2000-12-16 | 2002-06-19 | Aventis Pharma Deutschland GmbH | Health promoting compositions |
JP4183060B2 (ja) | 2002-04-26 | 2008-11-19 | 株式会社ファンケル | 利尿剤 |
JP4613017B2 (ja) | 2004-02-16 | 2011-01-12 | 株式会社ファンケル | ダイフラクトースアンハイドライド含有経口組成物 |
-
2004
- 2004-11-17 JP JP2004333663A patent/JP4723849B2/ja active Active
-
2005
- 2005-10-25 AT AT05799109T patent/ATE526835T1/de not_active IP Right Cessation
- 2005-10-25 US US11/719,239 patent/US8530446B2/en not_active Expired - Fee Related
- 2005-10-25 WO PCT/JP2005/019597 patent/WO2006054429A1/ja active Application Filing
- 2005-10-25 CN CN2005800390919A patent/CN101056644B/zh not_active Expired - Fee Related
- 2005-10-25 EP EP05799109A patent/EP1825856B1/en not_active Not-in-force
-
2008
- 2008-01-24 HK HK08100975.1A patent/HK1107266A1/xx not_active IP Right Cessation
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63269962A (ja) * | 1987-04-28 | 1988-11-08 | Natl Food Res Inst | 食品素材 |
JPH1143438A (ja) * | 1997-07-29 | 1999-02-16 | Nippon Beet Sugar Mfg Co Ltd | カルシウム吸収亢進組成物 |
WO1999007392A1 (fr) * | 1997-08-08 | 1999-02-18 | Otsuka Pharmaceutical Co., Ltd. | Compositions contenant de l'isoflavone |
JP2000204042A (ja) * | 1999-01-13 | 2000-07-25 | Nippon Mitsubishi Oil Corp | 環状オリゴ糖 |
WO2003090759A1 (fr) * | 2002-04-26 | 2003-11-06 | Fancl Corporation | Composition contenant du difructose anhydride et utilisation de celle-ci |
JP2004161619A (ja) * | 2002-11-11 | 2004-06-10 | Fancl Corp | 骨形成促進組成物 |
WO2004078989A1 (ja) * | 2003-03-05 | 2004-09-16 | Nippon Beet Sugar Mfg. Co., Ltd. | ジフルクトース・ジアンヒドリドiiiの精製方法 |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2036916A1 (en) * | 2006-06-20 | 2009-03-18 | Unitika, Ltd. | Composition for promoting the production of equol |
EP2036916A4 (en) * | 2006-06-20 | 2010-08-11 | Unitika Ltd | COMPOSITION FOR PROMOTING EQUOL PRODUCTION |
US8822432B2 (en) | 2006-06-20 | 2014-09-02 | Unitika Ltd. | Equol production accelerating composition |
WO2020004568A1 (ja) | 2018-06-28 | 2020-01-02 | アサヒグループホールディングス株式会社 | エクオール産生促進剤およびそれを含むエクオール産生促進用食品または飲料組成物 |
Also Published As
Publication number | Publication date |
---|---|
CN101056644B (zh) | 2011-01-19 |
CN101056644A (zh) | 2007-10-17 |
EP1825856A1 (en) | 2007-08-29 |
JP4723849B2 (ja) | 2011-07-13 |
EP1825856B1 (en) | 2011-10-05 |
WO2006054429A1 (ja) | 2006-05-26 |
US20090069269A1 (en) | 2009-03-12 |
US8530446B2 (en) | 2013-09-10 |
EP1825856A4 (en) | 2008-07-16 |
ATE526835T1 (de) | 2011-10-15 |
HK1107266A1 (en) | 2008-04-03 |
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