JP2005112793A - Bleaching cosmetic - Google Patents
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Abstract
Description
本発明は、新規な生薬成分を含んでなる美白化粧品に関する。 The present invention relates to a whitening cosmetic product comprising a novel herbal medicine component.
生薬成分を含んでなる美白化粧品として既に知られているものには、例えば、冬葵子、辛夷、中国産白朮、蒼朮の溶媒抽出物を含んでなる美白化粧品がある(下記特許文献1参照)。しかしながら、美白効果を有する生薬成分は、特許文献1に記載のものの他にも存在すると思われることから、このような生薬成分の探索は意義深いものである。
そこで本発明は、新規な生薬成分を含んでなる美白化粧品を提供することを目的とする。 Therefore, an object of the present invention is to provide a whitening cosmetic product comprising a novel herbal ingredient.
上記の点に鑑みてなされた本発明の美白化粧品は、請求項1記載の通り、玉竹、天門冬、桃仁、白附子、麦門冬、ビャクシ、ビャクキュウ、冬瓜子、丹参、茯苓、ビャクレン、白鮮皮、白僵蚕、土瓜根、ビャクシツリ、蔓荊子、菟絲子、細辛、藁本、杏仁、補骨脂、山薬、阿膠、ニクジュヨウ、杜仲、石斛、蓮肉、黄耆、何首烏、益母草、商陸、葛根、乳香、白薇、縮砂、カッコウ、木香、サクバイカ、香附子、半夏、烏賊骨、豚の膵臓から選ばれる少なくとも1種類の生薬成分を含んでなることを特徴とする。
また、請求項2記載の美白化粧品は、請求項1記載の美白化粧品において、2種類以上の生薬成分を含んでなることを特徴とする。
また、請求項3記載の美白化粧品は、請求項1記載の美白化粧品において、白附子および/または土瓜根を含んでなることを特徴とする。
The whitening cosmetics of the present invention made in view of the above points are as described in claim 1, such as cypress, tianmen winter, peach seed, white bean paste, barley winter, peanuts, sandalwood cucumbers, winter lions, dansan, strawberry, sandalwood, White skin, white birch, dope root, sandalwood root, vine, coconut, spicy, kakimoto, apricot kernel, prosthetic fat, mountain medicine, ginseng, cucumber, yochu, chuchu, sarcophagus, lotus, yellow cocoon It contains at least one herbal ingredient selected from beneficial herbs, commercial land, kudzu, frankincense, white rose, shrunk sand, cuckoo, wood incense, cassava, katsuki, half-summer, bandit bone, pork pancreas Features.
The whitening cosmetic product according to claim 2 is characterized in that in the whitening cosmetic product according to claim 1, two or more kinds of herbal medicine components are contained.
Further, the whitening cosmetic product according to claim 3 is the whitening cosmetic product according to claim 1, characterized in that it contains white bean paste and / or earthen root.
本発明によれば、新規な生薬成分を含んでなる美白化粧品が提供される。 According to the present invention, a whitening cosmetic product comprising a novel herbal ingredient is provided.
本発明の美白化粧品に含まれる生薬成分は、玉竹、天門冬、桃仁、白附子、麦門冬、ビャクシ、ビャクキュウ、冬瓜子、丹参、茯苓、ビャクレン、白鮮皮、白僵蚕、土瓜根、ビャクシツリ、蔓荊子、菟絲子、細辛、藁本、杏仁、補骨脂、山薬、阿膠、ニクジュヨウ、杜仲、石斛、蓮肉、黄耆、何首烏、益母草、商陸、葛根、乳香、白薇、縮砂、カッコウ、木香、サクバイカ、香附子、半夏、烏賊骨、豚の膵臓から選ばれる少なくとも1種類である。これらの生薬成分の中で好適な生薬成分としては、例えば、美白効果に加え保湿効果に優れる白附子や土瓜根などが挙げられる。生薬成分は、1種類を単独で用いてもよいが、2種類以上を組み合わせて用いれば美白効果の向上が期待できる。また、これらの生薬成分を冬葵子、辛夷、中国産白朮、蒼朮、白檀、白石脂、防風、桃花、人参、枸杞根、生地黄、巴戟天、大棗、当帰、天花粉、芍薬、沈香、丁香、明礬、甘草、黄柏、升麻、零陵香、月季花、甘松香、珍珠などの既に知られている美白効果を有する生薬成分と組み合わせて用いてもよい。 The herbal medicine ingredients contained in the whitening cosmetics of the present invention are: Jade bamboo, Tenmon winter, Taojin, Shiratsuko, Mumon winter, Bikaku, Byakukyu, Winter lion, Dansang, 茯苓, Byakuren, White skin, White candy, Earthenware Roots, peanuts, vines, eggplants, spicy, Kakimoto, apricot kernels, bone substitutes, mountain medicines, glue, cucumbers, chuchu, sarcophagus, lotus, twilight, bonito, profit mother grass, merchant land, kakkon, frankincense, It is at least one selected from white rose, shrunk sand, cuckoo, wood incense, sugar beet, katsuki, half summer, bandit bone, and porcine pancreas. Among these herbal medicine components, suitable herbal medicine ingredients include, for example, white bean paste and dope root, which are excellent in moisturizing effect in addition to the whitening effect. The herbal medicine component may be used alone, but if it is used in combination of two or more, the whitening effect can be expected. In addition, these herbal ingredients are added to winter coconut, hot pepper, Chinese white birch, cocoon, sandalwood, shiroishi fat, windproof, peach blossom, carrot, radish, dough yellow, 巴戟 天, 棗 棗, toki, heavenly pollen, glaze, You may use it in combination with the already known herbal medicine ingredients which have the whitening effect, such as agarwood, clove, agate, licorice, yellow cocoon, cinnamon, zero ling incense, moon flower, sweet pine incense, and rosary.
生薬成分を2種類以上組み合わせて用いる場合における好適な組み合わせとしては、例えば、以下の組み合わせが挙げられる(数字は重量配合比)。以下の組み合わせにはさらに豚の膵臓(適量の精製水を加えて数時間放置した後に非加熱状態で成分抽出した非加熱抽出液など)を組み合わせてもよい。
1. ビャクレン:白附子:ビャクシ:藁本=2:2:2:1
2. ビャクシ:桃仁:冬瓜子:玉竹=2:1:2:1
3. 玉竹:天門冬:麦門冬:土瓜根=2:1:1:3
4. 白鮮皮:白僵蚕:木香:細辛=2:2:1:1
5. 白附子:土瓜根:冬瓜子=1:1:1
6. 玉竹:杏仁:丹参=2:1:1
7. ビャクシ:白附子:ビャクキュウ:天門冬:麦門冬:桃仁:丹参:土瓜根=2:2:2:1:1:1:1:3
8. 白附子:土瓜根=1:1
9. 白附子:葛根:丹参=2:1:1
10. 白僵蚕:ビャクシ:細辛=3:4:3
11. ビャクシ:白附子:土瓜根:補骨脂:山薬:阿膠:ニクジュヨウ:杜仲=4:4:4:1:1:1:1:1
12. 細辛:土瓜根:何首烏=2:4:1
13. 白附子:土瓜根:ビャクシツリ:蔓荊子:菟絲子:益母草:蓮肉:商陸=2:2:2:1:1:1:1:1
14. 土瓜根:玉竹:桃仁:白附子:黄耆:カッコウ:細辛=3:2:2:3:1:1:1
15. 白附子:土瓜根:桃仁:冬瓜子:石斛:乳香:サクバイカ:烏賊骨=4:4:2:2:1:1:1:1
16. 白僵蚕:ビャクキュウ:ビャクシ:白附子:茯苓:白薇:縮砂:半夏=4:4:4:4:2:1:1:1
17. 玉竹:天門冬:麦門冬:丹参:土瓜根:香附子=1:1:1:1:1:1
18. ビャクシ:白附子:玉竹:益母草:何首烏:ニクジュヨウ:カッコウ:縮砂:木香=3:3:3:2:2:2:1:1:1
19. ビャクシ:細辛=2:1
20. 土瓜根:葛根=2:1
As a suitable combination in the case of using a combination of two or more kinds of crude drug components, for example, the following combinations may be mentioned (numbers are weight blending ratios). The following combinations may further be combined with porcine pancreas (such as a non-heated extract obtained by extracting components in a non-heated state after adding an appropriate amount of purified water and allowing it to stand for several hours).
1. Byakuren: Shirotsuji: Byakushi: Enomoto = 2: 2: 2: 1
2. Byakushi: Taojin: Fuyuko Reiko: Jade bamboo = 2: 1: 2: 1
3. Jade bamboo: Tenmon winter: Mumun winter: Dosone = 2: 1: 1: 3
4). White skin: white candy: mushrooms: spicy = 2: 2: 1: 1
5). Shirosuke: Dosone: Fuyuko Fuyu = 1: 1: 1
6). Jade bamboo: Anjin: Tansan = 2: 1: 1
7). Sandalwood: Shiratsuko: Sandalwood Kyu: Tenmon Winter: Mumon Winter: Taojin: Dansang: Dosone = 2: 2: 2: 1: 1: 1: 1: 3
8). Shirotsuki: Dosone = 1: 1
9. Shirotsuki: Kakkon: Tansan = 2: 1: 1
10. White birch: peony: spicy = 3: 4: 3
11. Byakushi: Shirotsuji: Dosone: Prosthetic fat: Mountain medicine: Agami: Nikujuyou: Tochu = 4: 4: 4: 1: 1: 1: 1: 1
12 Spicy: Dosone Root: What's 烏 = 2: 4: 1
13. Shirotsuko: Dosone Root: Bikakutsuri: Jade lion: Lion lion: Benthic grass: Lotus meat: Commercial land = 2: 2: 2: 1: 1: 1: 1: 1
14 Dossone: Jade bamboo: Momojin: Shirotsuko: Twilight: Cuckoo: Spicy = 3: 2: 2: 3: 1: 1: 1
15. Shirotsuki: Dosone: Tomojin: Fuyu Insuko: Ishizuchi: Nyuka: Sakubaika: Bandai Bone = 4: 4: 2: 2: 1: 1: 1: 1
16. White camellia: sandalwood: sandalwood: white eggplant: white sand: rose: shrunk sand: half-summer = 4: 4: 4: 4: 2: 1: 1: 1
17. Jade bamboo: Tenmon winter: Mumon winter: Dansang: Dosone: Katsukiko = 1: 1: 1: 1: 1: 1
18. Jellyfish: Shiratsuko: Jade bamboo: Profit mother grass: What neck: Nikujuyou: Cuckoo: Shredded sand: Scent of wood = 3: 3: 3: 2: 2: 2: 1: 1: 1
19. Byakushi: Spicy = 2: 1
20. Dosone: Kuzune = 2: 1
生薬成分は、例えば、その乾燥物の細切物や粉砕物を、スクワランやホホバ油などの液状油、ミツロウやセチルアルコールなどの固体油、グリセリンや1,3−ブチレングリコールなどの保湿剤などとともに自体公知の方法で製剤化することで、ローション、クリーム、乳液、パック、洗顔剤、ファンデーションなどの各種製剤形態の美白化粧品とされる。生薬成分として、それ自体、その乾燥物や細切物や粉砕物に溶媒を加えて抽出された抽出液、抽出液から溶媒を除去した抽出物、自体公知の精製手段を用いて得られた抽出精製物などを用いてもよい。ここで、抽出液を得るために用いることができる溶媒としては、水、エタノールなどのアルコール類の他、自体公知の溶媒が挙げられる。 Herbal medicine ingredients include, for example, chopped and pulverized dried products, liquid oils such as squalane and jojoba oil, solid oils such as beeswax and cetyl alcohol, and humectants such as glycerin and 1,3-butylene glycol. By formulating it by a method known per se, it is made into a whitening cosmetic product in various preparation forms such as lotion, cream, milky lotion, pack, facial cleanser and foundation. As a crude drug component, an extract obtained by adding a solvent to the dried product, shredded product or pulverized product itself, an extract obtained by removing the solvent from the extract, and an extraction obtained using a purification method known per se A purified product or the like may be used. Here, examples of the solvent that can be used to obtain the extract include alcohols such as water and ethanol, and solvents known per se.
以下、本発明を実施例により説明するが、本発明は以下の記載に基づいて限定して解釈されるものではない。 EXAMPLES Hereinafter, although an Example demonstrates this invention, this invention is limited and interpreted based on the following description.
製剤例1:美白化粧品その1(クリーム)
上記段落番号7に記載の生薬成分の組み合わせ例2における4種類の生薬成分を含んでなる美白クリームを以下のようにして製造した。
所定の重量配合比で配合した4種類の生薬成分の混合物(各生薬成分の乾燥物を適度に粉砕して混合したもの)40gに精製水800mLを加え、約30分間沸騰加熱した後、濾過して混合生薬成分抽出液を得た。この抽出液を用いて以下の組成物Aを調製するとともに、以下の組成物Bを調製した。組成物Aと組成物Bをそれぞれ70℃まで加温し、組成物Aに組成物Bを攪拌しつつ徐々に加えた後、ゆっくり攪拌しつつ30℃まで冷却して美白クリームとした。なお、美白クリームは、混合生薬成分抽出液のかわりにこの抽出液の凍結乾燥粉末を用いて製造することもできる。
(組成物A)
混合生薬成分抽出液 45.9重量部
ヒアルロン酸ナトリウム 1.0 〃
4−ヒドロキシ安息香酸メチル 0.1 〃
香料 適量
(組成物B)
白色ワセリン 10.0重量部
セタノール 10.0 〃
セスキオレイン酸ソルビタン 5.0 〃
テトラオレイン酸ポリオキシエチレンソルビット40E.O.
0.5 〃
ミツロウ 4.0 〃
トリ(カプリルカプリン酸)グリセリン 8.0 〃
イソステアリルアルコール 5.0 〃
スクアラン 10.0 〃
DL−α−酢酸トコフェロール 0.5 〃
Formulation Example 1: Whitening Cosmetics 1 (Cream)
A whitening cream comprising four kinds of herbal ingredients in combination example 2 of herbal ingredients described in paragraph 7 above was produced as follows.
Add 800 mL of purified water to 40 g of a mixture of 4 types of herbal ingredients blended at a predetermined weight blending ratio (mixed appropriately pulverized dry ingredients of each herbal medicine), boil and heat for about 30 minutes, and then filter. Thus, a mixed herbal medicine component extract was obtained. The following composition A was prepared using this extract, and the following composition B was prepared. Composition A and Composition B were each heated to 70 ° C., composition B was gradually added to composition A with stirring, and then cooled to 30 ° C. with slow stirring to obtain a whitening cream. In addition, whitening cream can also be manufactured using the freeze-dried powder of this extract instead of the mixed herbal medicine component extract.
(Composition A)
Mixed herbal medicine component extract 45.9 parts by weight
Sodium hyaluronate 1.0 〃
Methyl 4-hydroxybenzoate 0.1 〃
Perfume appropriate amount (Composition B)
10.0 parts by weight of white petrolatum
Cetanol 10.0 〃
Sorbitan sesquioleate 5.0 〃
Tetraoleic acid polyoxyethylene sorbit 40E.O.
0.5 〃
Beeslow 4.0 〃
Tri (caprylcapric acid) glycerin 8.0 〃
Isostearyl alcohol 5.0 〃
Squalane 10.0 〃
DL-α-tocopherol acetate 0.5 〃
製剤例2:美白化粧品その2(ローション)
上記段落番号7に記載の生薬成分の組み合わせ例8における2種類の生薬成分を含んでなる美白ローションを以下のようにして製造した。
所定の重量配合比で配合した2種類の生薬成分の混合物(各生薬成分の乾燥物を適度に粉砕して混合したもの)40gに精製水800mLを加え、約30分間沸騰加熱した後、濾過して混合生薬成分抽出液を得た。この抽出液を用いて常法により美白ローションとした。なお、美白ローションは、混合生薬成分抽出液のかわりにこの抽出液の凍結乾燥粉末を用いて製造することもできる。
混合生薬成分抽出液 89.6重量部
アテロコラーゲン(2%) 2.5 〃
ソルビット液 2.0 〃
Tween80 0.5 〃
エタノール 5.0 〃
パラオキシ安息香酸メチル 0.2 〃
香料 0.2 〃
Formulation Example 2: Whitening Cosmetics 2 (Lotion)
A whitening lotion comprising two types of herbal ingredients in the combination example 8 of herbal ingredients described in paragraph 7 above was produced as follows.
Add 800 mL of purified water to 40 g of a mixture of two types of herbal ingredients blended at a specified weight blending ratio (mixed and appropriately ground dry products of each herbal ingredient), boil and heat for about 30 minutes, and then filter. Thus, a mixed herbal medicine component extract was obtained. Using this extract, a whitening lotion was prepared by a conventional method. The whitening lotion can also be produced by using a freeze-dried powder of this extract instead of the mixed herbal medicine extract.
Mixed herbal medicine component extract 89.6 parts by weight
Atelocollagen (2%) 2.5 〃
Sorbit liquid 2.0 〃
Tween80 0.5 〃
Ethanol 5.0 〃
Methyl paraoxybenzoate 0.2 〃
Fragrance 0.2 〃
試験例1:製剤例1の美白クリームの美白効果
試験についての同意が得られた3人の被験者(アトピーなどの皮膚疾患を持たずかつ過敏な皮膚でない女性)に製剤例1の美白クリームを顔面に毎日朝晩、約3ヶ月間、適量塗布してもらい、その美白効果と保湿効果を以下の主観的判定基準に基づいて得点化した。また、皮膚の痒みやかぶれや腫れなどの副作用の有無についても調べた。
とても効果があった ・・・+2
やや効果があった ・・・+1
効果がなかった ・・・ 0
悪化した ・・・−1
結果を表1に示す。表1から明らかなように、製剤例1の美白クリームは、副作用がなく、美白効果に優れるとともに保湿効果を併せ持つことがわかった。
Test Example 1: The whitening effect of the whitening cream of Formulation Example 1 The facial whitening cream of Formulation Example 1 was applied to three subjects (women who did not have a skin disease such as atopy and were not sensitive skin) who had consented to the test. Each morning and evening, an appropriate amount was applied for about 3 months, and the whitening effect and moisturizing effect were scored based on the following subjective criteria. We also examined the presence of side effects such as itching, rash, and swelling of the skin.
Very effective ... +2
Slightly effective ... + 1
There was no effect ... 0
-1
The results are shown in Table 1. As apparent from Table 1, it was found that the whitening cream of Formulation Example 1 had no side effects, had an excellent whitening effect, and had a moisturizing effect.
試験例2:製剤例2の美白ローションの美白効果
試験についての同意が得られた3人の被験者(アトピーなどの皮膚疾患を持たずかつ過敏な皮膚でない女性)に製剤例2の美白ローションを顔面に毎日朝晩、約3ヶ月間、適量塗布してもらい、その美白効果と保湿効果を試験例1記載の主観的判定基準に基づいて得点化した。また、皮膚の痒みやかぶれや腫れなどの副作用の有無についても調べた。
結果を表2に示す。表2から明らかなように、製剤例2の美白ローションは、副作用がなく、美白効果に優れるとともに保湿効果を併せ持つことがわかった。
Test Example 2: Whitening effect of whitening lotion of Formulation Example 2 Facial whitening lotion of Formulation Example 2 was given to three subjects (women who did not have skin diseases such as atopy and were not sensitive skin) with the consent of the test. Each morning and evening, an appropriate amount was applied for about 3 months, and the whitening effect and moisturizing effect were scored based on the subjective judgment criteria described in Test Example 1. We also examined the presence of side effects such as itching, rash, and swelling of the skin.
The results are shown in Table 2. As is clear from Table 2, it was found that the whitening lotion of Formulation Example 2 had no side effects, was excellent in whitening effect and had a moisturizing effect.
本発明は、新規な生薬成分を含んでなる美白化粧品が提供される点において産業上の利用可能性を有する。 The present invention has industrial applicability in that a whitening cosmetic product comprising a novel herbal ingredient is provided.
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Cited By (15)
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JP2005298503A (en) * | 2004-04-07 | 2005-10-27 | Amorepacific Corp | Moisture-retention cosmetic composition containing pulverized polygonatum offcinale |
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