JP2004517967A5 - - Google Patents
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- Publication number
- JP2004517967A5 JP2004517967A5 JP2002565948A JP2002565948A JP2004517967A5 JP 2004517967 A5 JP2004517967 A5 JP 2004517967A5 JP 2002565948 A JP2002565948 A JP 2002565948A JP 2002565948 A JP2002565948 A JP 2002565948A JP 2004517967 A5 JP2004517967 A5 JP 2004517967A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10063294A DE10063294A1 (en) | 2000-12-19 | 2000-12-19 | New N-(heterocyclyl-alkyl)-fused norbornylamine derivatives, are NHE3 inhibitors useful e.g. for treating respiratory disorders, renal failure, intestinal dysfunction, lipid metabolism disorders or proliferative diseases |
| PCT/EP2001/014422 WO2002066431A1 (en) | 2000-12-19 | 2001-12-07 | Substituted heterocyclo-norbornylamine derivatives, method for producing the same, their use as medicament or diagnostic agent and medicament containing the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004517967A JP2004517967A (en) | 2004-06-17 |
| JP2004517967A5 true JP2004517967A5 (en) | 2005-12-22 |
| JP4281993B2 JP4281993B2 (en) | 2009-06-17 |
Family
ID=7667788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002565948A Expired - Fee Related JP4281993B2 (en) | 2000-12-19 | 2001-12-07 | Substituted heterocyclic-norbornylamino derivatives, their preparation, their use as pharmaceuticals or diagnostics, and pharmaceuticals containing them |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6737423B2 (en) |
| EP (1) | EP1345902B1 (en) |
| JP (1) | JP4281993B2 (en) |
| AT (1) | ATE296802T1 (en) |
| CA (1) | CA2432208A1 (en) |
| DE (2) | DE10063294A1 (en) |
| ES (1) | ES2241746T3 (en) |
| IL (1) | IL156467A0 (en) |
| MX (1) | MXPA03004963A (en) |
| PT (1) | PT1345902E (en) |
| WO (1) | WO2002066431A1 (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7049333B2 (en) * | 2002-06-04 | 2006-05-23 | Sanofi-Aventis Deutschland Gmbh | Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis |
| US8729107B2 (en) * | 2002-12-06 | 2014-05-20 | Purdue Research Foundation | Pyridines for treating injured mammalian nerve tissue |
| JP4903385B2 (en) | 2002-12-06 | 2012-03-28 | パーデュー・リサーチ・ファウンデーション | Pyridines for treating damaged mammalian nervous tissue |
| WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| AU2009334511C1 (en) | 2008-12-31 | 2016-08-18 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| WO2012054110A2 (en) | 2010-07-07 | 2012-04-26 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| EP2590510B1 (en) | 2010-07-07 | 2016-09-28 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| KR102138390B1 (en) | 2012-08-21 | 2020-07-27 | 알데릭스, 인코포레이티드 | Compounds and methods for inhibiting nhe-mediaded antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| US10376481B2 (en) | 2012-08-21 | 2019-08-13 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| AU2014250956B2 (en) | 2013-04-12 | 2019-04-04 | Ardelyx, Inc. | NHE3-binding compounds and methods for inhibiting phosphate transport |
| EP3030252B1 (en) | 2013-08-09 | 2018-11-07 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| CA3049679A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Inhibitors of nhe-mediated antiport |
| EP3565808A1 (en) | 2017-01-09 | 2019-11-13 | Ardelyx, Inc. | Compounds useful for treating gastrointestinal tract disorders |
| IL272443B2 (en) | 2017-08-04 | 2024-02-01 | Ardelyx Inc | Glycyrrhetinic acid derivatives for treating hyperkalemia |
| AU2020218255A1 (en) | 2019-02-07 | 2021-09-09 | Ardelyx, Inc. | Glycyrrhetinic acid derivatives for use in treating hyperkalemia |
| US20200368223A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1317514A (en) * | 1970-11-30 | 1973-05-23 | Erba Carlo Spa | Imidazoline derivatives |
| DE2403138A1 (en) | 1974-01-23 | 1975-07-31 | Hoechst Ag | BENZYLAMINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION |
| US5371086A (en) * | 1991-03-15 | 1994-12-06 | The Green Cross Corporation | Aminopyridine compounds |
| WO1996040141A1 (en) | 1995-06-07 | 1996-12-19 | Acea Pharmaceuticals, Inc. | 4,5-bridged quinoxalinediones and quinolones and the use thereof as excitatory amino acid receptor antagonists |
| DE19633966A1 (en) | 1996-08-22 | 1998-02-26 | Hoechst Ag | Phenyl-substituted alkenylcarboxylic acid guanidines, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them |
| CZ20004727A3 (en) * | 1998-06-19 | 2002-03-13 | Pfizer Products Inc. | Derivatives of pyrrolo[2,3-d]pyrimidine |
| US6355660B1 (en) * | 1999-07-20 | 2002-03-12 | Dow Agrosciences Llc | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation |
| DE19960204A1 (en) * | 1999-12-14 | 2001-06-28 | Aventis Pharma Gmbh | Substituted norlbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them |
-
2000
- 2000-12-19 DE DE10063294A patent/DE10063294A1/en not_active Withdrawn
-
2001
- 2001-12-07 MX MXPA03004963A patent/MXPA03004963A/en active IP Right Grant
- 2001-12-07 PT PT01273771T patent/PT1345902E/en unknown
- 2001-12-07 JP JP2002565948A patent/JP4281993B2/en not_active Expired - Fee Related
- 2001-12-07 EP EP01273771A patent/EP1345902B1/en not_active Expired - Lifetime
- 2001-12-07 WO PCT/EP2001/014422 patent/WO2002066431A1/en active IP Right Grant
- 2001-12-07 CA CA002432208A patent/CA2432208A1/en not_active Abandoned
- 2001-12-07 IL IL15646701A patent/IL156467A0/en unknown
- 2001-12-07 AT AT01273771T patent/ATE296802T1/en not_active IP Right Cessation
- 2001-12-07 ES ES01273771T patent/ES2241746T3/en not_active Expired - Lifetime
- 2001-12-07 DE DE50106414T patent/DE50106414D1/en not_active Expired - Lifetime
- 2001-12-18 US US10/020,241 patent/US6737423B2/en not_active Expired - Fee Related