JP2004130123A5 - - Google Patents

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JP2004130123A5
JP2004130123A5 JP2003323590A JP2003323590A JP2004130123A5 JP 2004130123 A5 JP2004130123 A5 JP 2004130123A5 JP 2003323590 A JP2003323590 A JP 2003323590A JP 2003323590 A JP2003323590 A JP 2003323590A JP 2004130123 A5 JP2004130123 A5 JP 2004130123A5
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Japan
Prior art keywords
fluororesin
guide wire
medical guide
coating layer
particulate
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JP2003323590A
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Japanese (ja)
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JP3876243B2 (en
JP2004130123A (en
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Priority to JP2003323590A priority Critical patent/JP3876243B2/en
Priority claimed from JP2003323590A external-priority patent/JP3876243B2/en
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Publication of JP2004130123A5 publication Critical patent/JP2004130123A5/ja
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Publication of JP3876243B2 publication Critical patent/JP3876243B2/en
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Claims (18)

金属製ワイヤーの表面に少なくともフッ素樹脂被膜層が形成されている医療用ガイドワイヤーであって、
前記フッ素樹脂被膜層に粒子状物質が存在し、前記フッ素樹脂被膜と前記粒子状物質とは一体化焼成され、
前記フッ素樹脂被膜層は粒子状物質を覆い、かつ前記粒子状物質の少なくとも一部は表面凸形状の突起形成されている医療用ガイドワイヤー。
A medical guide wire in which at least a fluororesin coating layer is formed on the surface of a metal wire,
Particulate matter is present in the fluororesin coating layer, and the fluororesin coating and the particulate matter are integrally fired,
The medical guide wire in which the fluororesin coating layer covers a particulate substance, and at least a part of the particulate substance is formed as a protrusion having a convex surface.
前記フッ素樹脂被膜層の内層にさらにプライマー層が形成され、
前記プライマー層及びフッ素樹脂被膜層から選ばれる少なくとも一つの層に粒子状物質が存在し、
最外層の前記フッ素樹脂被膜層は前記粒子状物質を覆い、かつ前記粒子状物質の少なくとも一部は表面凸形状の突起形成されている請求項1に記載の医療用ガイドワイヤー。
A primer layer is further formed on the inner layer of the fluororesin coating layer,
Particulate matter is present in at least one layer selected from the primer layer and the fluororesin coating layer,
The fluorine resin coating layer of the outermost layer covers said particulate material, and medical guide wire of claim 1, wherein at least a portion of the particulate material which is formed on the projection surface convex.
前記フッ素樹脂被膜層に粒子状物質を含み、前記粒子状物質がフッ素樹脂であり、前記フッ素樹脂被膜と前記粒子状物質とは一体化焼成されている請求項1又は2に記載の医療用ガイドワイヤー。   The medical guide according to claim 1 or 2, wherein the fluororesin coating layer includes a particulate material, the particulate material is a fluororesin, and the fluororesin coating and the particulate material are integrally fired. wire. 前記フッ素樹脂被膜層及び前記粒子状物質が、ポリテトラフルオロエチレン(PTFE)、テトラフルオロエチレン−パーフルオロアルキルビニルエーテル共重合体(PFA)、ポリクロロトリフルオロエチレン(PCTFE)、ポリ弗化ビニリデン(PVDF)、ポリ弗化ビニル(PVF)、テトラフルオロエチレン−ヘキサフルオロプロピレン共重合体(FEP)、テトラフルオロエチレン−エチレン共重合体(PETFE)から選ばれる少なくとも一つを含む請求項1又は2に記載の医療用ガイドワイヤー。 The fluororesin coating layer and the particulate material are polytetrafluoroethylene (PTFE), tetrafluoroethylene-perfluoroalkyl vinyl ether copolymer (PFA), polychlorotrifluoroethylene (PCTFE), polyvinylidene fluoride (PVDF). ), polyvinyl fluoride (PVF), tetrafluoroethylene - hexafluoropropylene copolymer (FEP), tetrafluoroethylene - according to claim 1 or 2 comprising at least one selected from ethylene copolymer (PETFE) Medical guidewire. 前記フッ素樹脂被膜層の厚みが、1μm以上50μm以下である請求項1〜4のいずれかに記載の医療用ガイドワイヤー。   The medical guide wire according to any one of claims 1 to 4, wherein the fluororesin coating layer has a thickness of 1 µm to 50 µm. 前記突起の平均高さが、0.1μm以上20μm以下である請求項1に記載の医療用ガイドワイヤー。   The medical guide wire according to claim 1, wherein an average height of the protrusions is 0.1 µm or more and 20 µm or less. 前記フッ素樹脂被膜層表面は、平坦部と多数の凸形状の突起が混在している請求項1に記載の医療用ガイドワイヤー。   The medical guide wire according to claim 1, wherein the surface of the fluororesin coating layer includes a flat portion and a number of convex protrusions. 前記凸形状の突起の密度が、平均1個/0.01mm2以上である請求項1,6又は7に記載の医療用ガイドワイヤー。 The medical guide wire according to claim 1, 6 or 7, wherein a density of the convex protrusions is an average of 1 piece / 0.01 mm 2 or more. 前記粒子状物質がプライマー層に存在しており、粒子状物質がフッ素樹脂か又は前記フッ素樹脂被膜層よりも融点が高い耐熱性物質である請求項2に記載の医療用ガイドワイヤー。   The medical guide wire according to claim 2, wherein the particulate substance is present in the primer layer, and the particulate substance is a fluororesin or a heat-resistant substance having a melting point higher than that of the fluororesin coating layer. 前記粒子状物質がガラス粒子、金属粒子、プラスチック粒子、無機粒子及びセラミックス粒子から選ばれる少なくとも一つである請求項9に記載の医療用ガイドワイヤー。   The medical guide wire according to claim 9, wherein the particulate substance is at least one selected from glass particles, metal particles, plastic particles, inorganic particles, and ceramic particles. 前記粒子状物質の平均粒子径がプライマー層の膜厚以上であって、平均粒子径が0.5〜30μmの範囲である請求項9に記載の医療用ガイドワイヤー。   The medical guide wire according to claim 9, wherein an average particle diameter of the particulate matter is equal to or greater than a film thickness of the primer layer, and an average particle diameter is in a range of 0.5 to 30 µm. 金属製ワイヤーの表面に少なくともフッ素樹脂被膜層を形成した医療用ガイドワイヤーの製造方法であって、
フッ素樹脂ディスパージョン中に突起用粒子状物質を混合してコーティング溶液を調製し、
前記溶液を前記金属製ワイヤーの表面に塗布し、乾燥後、前記フッ素樹脂ディスパージョンのフッ素樹脂の融点以上に加熱焼成することにより、
前記フッ素樹脂被膜層に前記粒子状物質を存在させ、
前記フッ素樹脂被膜層は前記粒子状物質を覆い一体化焼成され、かつ前記粒子状物質の少なくとも一部は表面凸形状の突起形成されていることを特徴とする医療用ガイドワイヤーの製造方法。
A method for producing a medical guide wire in which at least a fluororesin coating layer is formed on the surface of a metal wire,
Prepare the coating solution by mixing the particulate material for protrusions in the fluororesin dispersion,
The solution is applied to the surface of the metal wire, dried, and heated and fired above the melting point of the fluororesin of the fluororesin dispersion.
The presence of the particulate material to the fluorocarbon resin coating layer,
The fluorine resin coating layer is integrated sintered cover the particulate material, and manufacturing method of a medical guide wire and at least a part of the particulate material is formed on the projection surface convex.
金属製ワイヤーの表面にプライマー層とフッ素樹脂被膜層をこの順番で形成した医療用ガイドワイヤーの製造方法であって、
プライマー溶液及びフッ素樹脂ディスパージョン溶液から選ばれる少なくとも一つの溶液中に粒子状物質を混合し、
前記プライマー溶液とフッ素樹脂ディスパージョン溶液を前記金属製ワイヤーの表面にこの順番に塗布し、乾燥し、
最終工程で前記フッ素樹脂ディスパージョンのフッ素樹脂の融点以上に加熱焼成することにより、最外層の前記フッ素樹脂被膜層が前記粒子状物質を覆い一体化焼成され、かつ前記粒子状物質の少なくとも一部は表面凸形状の突起形成されていることを特徴とする医療用ガイドワイヤーの製造方法。
A method for producing a medical guide wire in which a primer layer and a fluororesin coating layer are formed in this order on the surface of a metal wire,
Mix particulate matter in at least one solution selected from a primer solution and a fluororesin dispersion solution,
The primer solution and the fluororesin dispersion solution are applied to the surface of the metal wire in this order and dried.
In the final step, the outermost layer of the fluororesin coating layer is integrally fired so as to cover the particulate matter by heating and firing above the melting point of the fluororesin of the fluororesin dispersion, and at least a part of the particulate matter method for producing a medical guide wire which is characterized in that it is formed on projections of the surface convex shape.
前記被覆用フッ素樹脂ディスパージョン溶液中のフッ素樹脂固形分濃度が、20〜60重量%である請求項12又は13に記載の医療用ガイドワイヤーの製造方法。   The method for producing a medical guide wire according to claim 12 or 13, wherein a fluororesin solid content concentration in the coating fluororesin dispersion solution is 20 to 60% by weight. 前記粒子状物質の添加量をA、前記フッ素樹脂ディスパージョン中の固形分をBとしたとき、[A/(A+B)]×100が1〜60重量%である請求項12〜14のいずれかに記載の医療用ガイドワイヤーの製造方法。   [A / (A + B)] × 100 is 1 to 60% by weight, where A is the amount of the particulate matter added and B is the solid content in the fluororesin dispersion. The manufacturing method of the medical guide wire as described in 1 .. 前記粒子状物質の平均粒子径が、0.5〜30μmである請求項12又は13に記載の医療用ガイドワイヤーの製造方法。   The method for producing a medical guide wire according to claim 12 or 13, wherein an average particle diameter of the particulate matter is 0.5 to 30 µm. 前記プライマー樹脂溶液中に、粒子状物質を混合してコーティング溶液を調製する請求項13に記載医療用ガイドワイヤーの製造方法。   The method for producing a medical guide wire according to claim 13, wherein a particulate matter is mixed in the primer resin solution to prepare a coating solution. 前記粒子状物質の存在量が、前記プライマー樹脂溶液の固形分重量に対して1〜50重量%である請求項17に記載の医療用ガイドワイヤーの製造方法。
The method for producing a medical guide wire according to claim 17, wherein the abundance of the particulate matter is 1 to 50% by weight based on the solid content weight of the primer resin solution.
JP2003323590A 2002-09-20 2003-09-16 Medical guide wire and manufacturing method thereof Expired - Lifetime JP3876243B2 (en)

Priority Applications (1)

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JP2003323590A JP3876243B2 (en) 2002-09-20 2003-09-16 Medical guide wire and manufacturing method thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002276139 2002-09-20
JP2003323590A JP3876243B2 (en) 2002-09-20 2003-09-16 Medical guide wire and manufacturing method thereof

Publications (3)

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JP2004130123A JP2004130123A (en) 2004-04-30
JP2004130123A5 true JP2004130123A5 (en) 2006-09-07
JP3876243B2 JP3876243B2 (en) 2007-01-31

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Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006068497A (en) * 2004-08-03 2006-03-16 Ist:Kk Method for manufacturing medical wire and medical wire
JP2006320638A (en) * 2005-05-20 2006-11-30 Ist Corp Method for manufacturing medical wire
CA2622519A1 (en) * 2005-09-15 2007-03-29 Wilson-Cook Medical Inc. Multiple stage wire guide
JP2008086575A (en) 2006-10-02 2008-04-17 Ist Corp Manufacturing method for colored medical tool
JP5249591B2 (en) * 2007-03-23 2013-07-31 テルモ株式会社 Guide wire
US9028427B2 (en) 2007-03-14 2015-05-12 Terumo Kabushiki Kaisha Guide wire
JP2016168063A (en) * 2013-07-29 2016-09-23 テルモ株式会社 Guide wire
JP2018103109A (en) * 2016-12-27 2018-07-05 東洋紡株式会社 Electret filter and method for manufacturing electret filter
JP2018103108A (en) * 2016-12-27 2018-07-05 東洋紡株式会社 Electret filter
JP2018188621A (en) * 2017-04-28 2018-11-29 アクロス株式会社 Coat for slide members and slide member having the same
JPWO2022070424A1 (en) * 2020-10-02 2022-04-07
JPWO2022130632A1 (en) * 2020-12-18 2022-06-23

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