JP2003284781A - Medical guide wire - Google Patents
Medical guide wireInfo
- Publication number
- JP2003284781A JP2003284781A JP2002090150A JP2002090150A JP2003284781A JP 2003284781 A JP2003284781 A JP 2003284781A JP 2002090150 A JP2002090150 A JP 2002090150A JP 2002090150 A JP2002090150 A JP 2002090150A JP 2003284781 A JP2003284781 A JP 2003284781A
- Authority
- JP
- Japan
- Prior art keywords
- guide wire
- medical guide
- coating layer
- coil
- marker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09058—Basic structures of guide wires
- A61M2025/09075—Basic structures of guide wires having a core without a coil possibly combined with a sheath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09058—Basic structures of guide wires
- A61M2025/09083—Basic structures of guide wires having a coil around a core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09166—Guide wires having radio-opaque features
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、心臓血管系内等に
カテーテルを導入する際に、そのカテーテルの挿入を安
全確実にするために用いる医療用ガイドワイヤに関する
ものである。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a medical guide wire used for ensuring safety of insertion of a catheter when introducing the catheter into the cardiovascular system or the like.
【０００２】[0002]
【従来の技術】医療用ガイドワイヤ（以下、単にガイド
ワイヤという）は、極細の可撓性線条体にして曲りくね
った複雑な血管や分岐血管に先端部から挿入して、体外
に位置する手元部を回転させながら押し引き操作して血
管内を進行させ、その挿入進行状態を放射線投射映像で
視認確認しながら適正な血管内進行を図る挿入手法が採
られている。従って、その先端部分は高度の柔軟性・可
撓性と血管内での高摺動性を有し、かつ放射線造影によ
る視認性を備えた高品質が要求される。2. Description of the Related Art A medical guide wire (hereinafter, simply referred to as a guide wire) is placed outside a body by inserting it from a distal end into a complicated blood vessel or a branch blood vessel which is formed into an extremely fine flexible filament body. An insertion method has been adopted in which the proximal portion is pushed and pulled while rotating to advance inside the blood vessel, and the progress of the insertion is visually confirmed by a radiation projection image to appropriately advance the blood vessel. Therefore, the tip portion is required to have high flexibility and flexibility, high slidability in the blood vessel, and high quality with visibility by radiography.
【０００３】そこで、以上の要求品質に応えるガイドワ
イヤ１５として（図６参照）極細径のＳＵＳ材（ステン
レス材）等の円形線の芯線２の先端部分に放射線不透過
材の円管体（またはコイルばね体）を密着固着した放射
線不透過マーカー１６を設け、その放射線不透過マーカ
ー１６を含む芯線２を「タングステン・硫酸バリウム・
酸化ビスマス等を含有する樹脂被覆１７」で埋め込んだ
形態の公知例があり、その放射線不透過性の「マーカー
６と樹脂被覆１７」の放射線造影によって血管内挿入状
態を視認把握するように成っている。Therefore, as the guide wire 15 which meets the above required quality (see FIG. 6), a circular tube body (or a radiopaque material) is attached to the tip of the core wire 2 of a circular wire such as SUS material (stainless steel) having an extremely small diameter (or A radiopaque marker 16 having a coil spring body adhered and fixed thereto is provided, and the core wire 2 including the radiopaque marker 16 is made of "tungsten / barium sulfate.
There is a known example in which the resin coating 17 containing bismuth oxide or the like is embedded, and the radiopaque radiography of the “marker 6 and the resin coating 17” is used to visually recognize the insertion state in the blood vessel. There is.
【０００４】[0004]
【発明が解決しようとする課題】以上の従来のガイドワ
イヤ１５は、放射線不透過マーカー１６の存在部分が芯
線２を膨径化した剛直部となるので、血管内で極小曲げ
したとき放射線不透過マーカー１６の両側に急激曲げ１
８を生じて、先端部分７の可撓性を低下して血管内挿入
性を阻害する。In the conventional guide wire 15 described above, since the portion where the radiopaque marker 16 exists is a rigid portion in which the core wire 2 is bulged, the radiopaque material is bent when it is extremely bent in the blood vessel. Bend sharply on both sides of marker 16 1
8 to reduce the flexibility of the tip portion 7 and impede intravascular insertability.
【０００５】そして、放射線不透過材を混入して成る樹
脂被覆１７は、放射線不透過材が概ね７５重量％以上の
高含有率にして、その高含有率によって「外力による伸
び」が特段に低下しているので前記の急激曲げ１８の曲
げ変形に追従できず、曲げによる集中応力によって芯線
・樹脂被覆１７の亀裂破損等の損傷をもたらす難点があ
る。The resin coating 17 formed by mixing the radiopaque material has a high content of the radiopaque material of approximately 75% by weight or more, and "extension due to external force" is significantly reduced due to the high content. Therefore, the bending deformation of the abrupt bending 18 cannot be followed, and there is a problem that the concentrated stress due to bending causes damage such as crack breakage of the core wire / resin coating 17.
【０００６】本発明は、以上の従来技術の難点を解消す
る医療用ガイドワイヤを提供するものである。The present invention provides a medical guide wire that overcomes the above-mentioned drawbacks of the prior art.
【０００７】[0007]
【課題を解決するための手段】以上の技術課題を解決す
る本発明の医療用ガイドワイヤは「金属質の芯線に樹脂
被覆を設けた医療用ガイドワイヤの先端部分において、
前記芯線が偏平形態にして、前記樹脂被覆が、放射線不
透過材不存在の樹脂層にして、かつ、管状またはコイル
ばね状の放射線不透過材から成る放射線造影マーカーを
外周に装着した第１被覆層と、該第１被覆層と該放射線
造影マーカーを埋め込む放射線不透過材存在の樹脂層の
第２被覆層から成る構造」に成っている。Means for Solving the Problems The medical guide wire of the present invention for solving the above technical problems is described as follows: "In the distal end portion of the medical guide wire in which a resin coating is provided on a metallic core wire,
A first coating in which the core wire has a flat shape, the resin coating is a resin layer without a radiopaque material, and a radiographic marker made of a radiopaque material in the form of a tubular or coil spring is attached to the outer periphery. A layer and a first coating layer and a second coating layer of a resin layer containing a radiopaque material for embedding the radiographic marker ".
【０００８】即ち、前記構成の本発明の医療用ガイドワ
イヤは、放射線投影によって映像画面上に現わして血管
内の挿入進行状態を視認把握可能にする放射線造影マー
カーを「従来技術のように芯線に直接固定しないで」該
芯線を包み込む柔軟質樹脂層の前記第１被覆層上にセッ
トした「材料力学上の弾性床上の梁」の思想から成る
「柔軟質弾性層上の金属質放射線造影マーカー」に構成
して、該放射線造影マーカーを先端部分の極小曲げ変形
に柔軟に追従変位可能にした構造を特徴とするものであ
る。That is, in the medical guide wire of the present invention having the above-described structure, the radiographic marker which appears on the image screen by radiation projection and enables visual recognition of the insertion progress state in the blood vessel is "core wire as in the prior art. “Radiation marker on metallic elastic layer on flexible elastic layer” composed of the idea of “beam on elastic floor in terms of material mechanics” set on the first coating layer of the flexible resin layer that wraps the core wire without being directly fixed to And a structure in which the radiographic contrast marker can be flexibly displaced in accordance with the minimal bending deformation of the distal end portion.
【０００９】そして、前記基本構成の本発明の医療用ガ
イドワイヤは、前記技術思想に基づく特有作用のさらな
る向上を図る技術意図から「前記第１・第２被覆層の間
に放射線不透過材不存在の中間被覆層を介層した３層構
造」の態様を採択する。Further, the medical guide wire of the present invention having the above-mentioned basic constitution is "a radiopaque material is impermeable between the first and second coating layers" from the technical intention of further improving the peculiar action based on the technical idea. A three-layer structure with an intermediate coating layer present is interposed.
【００１０】そして、前記の放射線造影マーカーは「管
長方向に切設したスリットつき円管形態」「周壁に係止
孔群を貫設した円管形態」「コイル線間にクリアランス
を設けたコイルばね体形態」「該線間クリアランスの存
在・不存在ゾーンを併存させたコイルばね体形態」「つ
づみ型コイルばね体形態」或は「横断面長方形状の芯線
と相似形態の長方形管体」等の多様な態様を採択して、
後述する本発明の特有作用のさらなる向上を図る。な
お、前記のコイルばね体とは「コイルばね機能が存在し
ない単なるコイルばね形状」のものを含めたものを意味
する。The radiographic marker is "a circular tube shape with a slit cut in the tube length direction", "a circular tube shape in which locking holes are formed through the peripheral wall", and "a coil spring having a clearance between coil wires". "Body shape""Coil spring body shape in which the existence / non-existence of the clearance between the lines coexists""Tsut type coil spring body shape" or "Rectangular tube body similar in shape to a core wire having a rectangular cross section" Adopting various aspects of
Further improvement of the specific action of the present invention described later is aimed at. The above-mentioned coil spring body means one including "a simple coil spring shape having no coil spring function".
【００１１】[0011]
【作用】以上の本発明の医療用ガイドワイヤは、放射線
造影マーカーが放射線不透過材不存在の前記第１被覆層
の上に装着された「柔軟弾性層上のセット形態」となる
ので、血管内へ挿入された先端部分が極小曲げ変形した
とき、該放射線造影マーカーは先端部分の極小曲げ変形
による曲げ応力によって柔軟質の第１被覆層へ喰い込ん
だり、第1被覆層または第1・第2被覆層と連動して弾性
変位して強大な曲げ応力を吸収緩和作用し、該先端部分
の高可撓性・高柔軟性を良好に確保することができる。In the medical guide wire of the present invention described above, the radiographic contrast marker is in the "set form on the flexible elastic layer" in which the radiographic marker is mounted on the first coating layer in the absence of the radiopaque material. When the tip portion inserted into the inside undergoes a minimal bending deformation, the radiographic marker is eroded into the flexible first coating layer by the bending stress due to the minimal bending deformation of the tip portion, or the first coating layer or the first and second coating layers. (2) It is possible to elastically displace in conjunction with the coating layer to absorb and relieve a large bending stress, thereby ensuring high flexibility and high flexibility of the tip portion.
【００１２】そして、樹脂被覆の芯材を構成する前記芯
線が平偏形状の板状体であることから、血管内の曲げ変
形は「該芯線の断面二次モーメントが最小の該板状体の
板厚中心が曲げ中立面となり、前記芯線と前記造影マー
カー間の前記第１被覆層の「層厚さ」が大となる部分が
「曲げによる引張り・圧縮」を担持する応力形態となる
ので、前記の第１被覆層の応力吸収作用と前記の高可撓
性・高柔軟性が特段に顕著になる。そして、以上の諸作
用から放射線造影マーカー部位の有害な急激曲げを防止
して芯線・被覆層の損傷を有効に防止する。Since the core wire forming the resin-coated core material is a flat plate-shaped body, the bending deformation in the blood vessel is caused by "a plate-shaped body having a minimum second moment of area of the core wire". Since the center of the plate thickness is the bending neutral surface, and the portion where the “layer thickness” of the first coating layer between the core wire and the contrast marker is large becomes a stress form that carries “pulling / compression by bending”. The stress absorbing action of the first coating layer and the high flexibility / high flexibility are particularly remarkable. From the above-mentioned various actions, the harmful sharp bending of the radiographic contrast marker site is prevented, and the core wire / covering layer is effectively prevented from being damaged.
【００１３】[0013]
【発明の実施の形態】まず、本発明第１実施例のガイド
ワイヤを図１を参照して説明する。即ち、ＳＵＳ材（ス
テンレス材）極細線の芯線２が全長の芯材を形成し、こ
の芯線２の少くとも先端部分７を「ポリアミド・ポリウ
レタン・ポリエステル、およびこれ等のエラストマー」
等の樹脂材から成る樹脂被覆３で埋め込んだ極細可撓性
線材のガイドワイヤ１において、先端部分７の芯線２は
先端部分７以外の芯線主部２Ａの円形線を偏平に塑性加
工して略長方形状横断面にした「厚さＴ・幅Ｂ」の偏平
部２Ｃに形成されている。BEST MODE FOR CARRYING OUT THE INVENTION First, a guide wire according to a first embodiment of the present invention will be described with reference to FIG. That is, the core wire 2 of SUS material (stainless steel) extra fine wire forms the core material of the entire length, and at least the tip portion 7 of the core wire 2 is made of "polyamide / polyurethane / polyester and elastomers thereof".
In the guide wire 1 of the ultrafine flexible wire embedded with the resin coating 3 made of a resin material such as the above, the core wire 2 of the distal end portion 7 is formed by flattening the circular wire of the core wire main portion 2A other than the distal end portion 7 into a flat shape. It is formed on the flat portion 2C having a "thickness T and a width B" in a rectangular cross section.
【００１４】そして、この芯線２の全体を埋め込む「放
射線不透過材を混入しない樹脂（可溶性ナイロン）の第
１被覆層４」が設けられ、先端部分７の第１被覆層４の
外周には「放射線不透過材からなる短小円管体の放射線
造影マーカーＭ（以下、単に造影マーカーＭという）が
装着され、さらに、この第１被覆層４を埋め込む「放射
線不透過材（酸化ビスマス）を混入した放射線不透過性
の第２被覆層５」が設定された２層構造の樹脂被覆３に
形成されている。A "first coating layer 4 of a resin (soluble nylon) that does not mix a radiopaque material" is provided to embed the entire core wire 2, and the outer periphery of the first coating layer 4 at the tip portion 7 is " A radiographic marker M (hereinafter simply referred to as a contrast marker M) of a short and small tubular body made of a radiopaque material is attached, and a “radiopaque material (bismuth oxide)” for embedding the first coating layer 4 is mixed. A radiopaque second coating layer 5 ″ is formed on the resin coating 3 having a two-layer structure.
【００１５】なお、この実施例の第２被覆層５の直径Ｄ
１＝０．４５粍、第１被覆層４の直径Ｄ２＝０．１６
粍、造影マーカーＭは外径＝０．２８粍・長さ＝２．０
粍、芯線２の偏平部２Ｃは幅Ｂ＝０．１３粍・厚さＴ＝
０．０３粍の寸法諸元にして、図中の２Ｂは芯線主部２
Ａと偏平部２Ｃ間の円形テーパー部である。The diameter D of the second coating layer 5 of this embodiment is
1 = 0.45, diameter of the first coating layer 4 D2 = 0.16
Abrasive, contrast marker M outer diameter = 0.28, length = 2.0
Roughness, flat portion 2C of core wire 2 has width B = 0.13, thickness T =
Based on the dimensions of 0.03 grit, 2B in the figure is the core wire main part 2
A circular taper portion between A and the flat portion 2C.
【００１６】以上の図１実施例のガイドワイヤ１は前記
の作用がある。即ち、造影マーカーＭが軟質の第１被覆
層４と第２被覆層５に間装されているので（図１（Ｃ）
（Ｄ）参照）先端部分７を血管内で極小半径でに曲げる
と、先端部分７は偏平部２Ｃの断面二次モーメントが小
なる偏平部２Ｃの板厚Ｔの中心を曲げ中立面Ｎとして曲
り変形する。従って、その曲げ応力を受けた造影マーカ
ーＭは、厚さＨが大なる第１被覆層４を容易に凹ませて
曲げ中立面Ｎを長軸とする楕円形に容易に変形したり、
第１・第２被覆層４・５に喰い込んだりして第１・第２
被覆層４・５と連動して弾性変位し、強大な曲げ応力を
吸収する作用を成し、先端部分７の極小曲げ変形を許容
するので、先端部分７の良好な高可撓性・高柔軟性が確
保できると共に、有害な「急激曲げ１８」の発生がなく
樹脂被覆３・芯線２の損傷を防止する。The guide wire 1 of the embodiment shown in FIG. 1 has the above-mentioned effect. That is, since the contrast marker M is interposed between the soft first coating layer 4 and the second coating layer 5 (FIG. 1C).
(See (D)) When the tip portion 7 is bent to a minimum radius in the blood vessel, the tip portion 7 has the center of the plate thickness T of the flat portion 2C having a small second moment of area of the flat portion 2C as the bending neutral plane N. It bends and deforms. Therefore, the contrast marker M that has received the bending stress easily deforms the first coating layer 4 having a large thickness H to easily deform into an elliptical shape having the bending neutral plane N as the major axis,
If the first and second coating layers 4 and 5 are bitten,
It elastically displaces in conjunction with the coating layers 4 and 5, acts to absorb a large bending stress, and allows a minimal bending deformation of the tip portion 7, so that the tip portion 7 has good flexibility and high flexibility. In addition to ensuring the property, harmful "rapid bending 18" does not occur and damage to the resin coating 3 and the core wire 2 is prevented.
【００１７】続いて、図２を参照して図１実施例の他の
態様変化を説明する。即ち、図１実施例に示す第１・第
２被覆層４・５と造影マーカーＭを備えたものにおい
て、図２（Ａ）に示すものは第１被覆層４と第２被覆層
５の間に「放射線不透過材を混入しない中間被覆層６
（第１被覆層４と同質の放射線透過性の軟質の樹脂
層）」を介層した３層構造に成っている。Next, another mode change of the embodiment of FIG. 1 will be described with reference to FIG. That is, in the one provided with the first and second covering layers 4 and 5 and the contrast marker M shown in FIG. 1 embodiment, the one shown in FIG. 2A is between the first covering layer 4 and the second covering layer 5. "Intermediate coating layer 6 containing no radiopaque material
(Radiation-transparent soft resin layer of the same quality as the first coating layer 4) ”is interposed to form a three-layer structure.
【００１８】この図２（Ａ）のものは造影マーカーＭが
軟質の第１被覆層４と中間被覆層６に間装にされたサン
ドイッチ形態を成すので、造影マーカーＭ部位の極小曲
げ時の造影マーカーＭの前記の変位性・応力吸収性が一
段と向上する。In FIG. 2A, the contrast marker M is sandwiched between the soft first coating layer 4 and the intermediate coating layer 6, so that the contrast marker M can be imaged at the time of minimal bending. The above-mentioned displacement and stress absorption of the marker M are further improved.
【００１９】そして、図２（Ｂ）に示すものは図１実施
例と同一の第１・第２被覆層４・５と円管状の造影マー
カーＭを有するものにおいて、先端部分７の芯線２の偏
平部２Ｃが前端方向へ厚さＴを漸減除減する段差８つき
横断面長方形状を成している。2B has the same first and second coating layers 4 and 5 and the circular tube-shaped contrast marker M as in the embodiment of FIG. The flat portion 2C has a rectangular cross section with a step 8 that gradually reduces and reduces the thickness T toward the front end.
【００２０】この図２（Ｂ）のものは段差８によるアン
カー作用によって芯線２の偏平部２Ｃと第１被覆層４の
係着係止力が向上し、先端部分７を極小曲率半径に変形
させたときの曲げ応力による芯線２と第１被覆層４の剥
離を防止し、先端部分７の形状安定ができる。In the structure shown in FIG. 2 (B), the anchoring force between the flat portion 2C of the core wire 2 and the first coating layer 4 is improved by the anchoring action of the step 8, and the tip portion 7 is deformed to the minimum radius of curvature. It is possible to prevent the core wire 2 and the first coating layer 4 from peeling off due to bending stress at the time, and to stabilize the shape of the tip portion 7.
【００２１】次に、図３を参照して本発明のガイドワイ
ヤ１の他の実施例を説明する。即ち、図１実施例と同様
な第１・第２被覆層４・５と円管状の造影マーカーＭを
有するものにおいて、図３（Ａ）の造影マーカーＭは管
長方向に伸びて周壁を２分割する分割スリット１０を切
設した形状を有し、図３（Ｂ）の造影マーカーＭは管体
周壁に小孔１１群を貫設した形状を有している。Next, another embodiment of the guide wire 1 of the present invention will be described with reference to FIG. That is, in the one having the first and second covering layers 4 and 5 and the circular tube-shaped contrast marker M similar to those of the embodiment of FIG. 1, the contrast marker M of FIG. 3A extends in the tube length direction and divides the peripheral wall into two. 3B has a shape in which the divided slits 10 are cut, and the contrast marker M in FIG. 3B has a shape in which a group of small holes 11 are formed in the peripheral wall of the tubular body.
【００２２】この分割スリット１０を有する造影マーカ
ーＭは血管内の極小曲げ変形時に軟質の第１被覆層４に
対して「曲げ応力による径の拡大・縮小変形」が容易に
なるので先端部分７の高可撓性・極小曲げ性がより向上
すると共に、造影マーカーＭ自体の拡径・縮径が容易に
なるので、第１被覆層４への装着セットがし易い。The contrast marker M having the divided slits 10 facilitates "diameter expansion / contraction deformation due to bending stress" with respect to the soft first coating layer 4 at the time of minimal bending deformation in the blood vessel, so that the distal end portion 7 of The flexibility and the minimal bendability are further improved, and the diameter of the contrast marker M itself is easily expanded / reduced, so that the first marker layer 4 can be easily attached and set.
【００２３】そして、小孔１１群を有するものは第２被
覆層５の樹脂が小孔１１に入り込むので造影マーカーＭ
の係着力が向上すると共に、極小曲げ時の第１・第２被
覆層４・５との連動変位性が向上する。In the case of the group having the small holes 11, since the resin of the second coating layer 5 enters the small holes 11, the contrast marker M
And the interlocking displaceability with the first and second coating layers 4 and 5 at the time of extremely small bending is improved.
【００２４】続いて、本発明のガイドワイヤ１の造影マ
ーカーＭの他の実施形態を図４を参照して説明する。即
ち、この図４に示す造影マーカーＭはコイルばね体にし
て、図４（Ａ）のものはコイル線１２間の線間クリアラ
ンスＣが連続するコイルばね体、図４（Ｂ）のものは隣
接コイル線が密着したコイル密部１３と線間クリアラン
スＣが存在するコイル疎部１４が混成配設された疎密コ
イルばね体に成っている。Next, another embodiment of the contrast marker M of the guide wire 1 of the present invention will be described with reference to FIG. That is, the contrast marker M shown in FIG. 4 is a coil spring body, the one shown in FIG. 4A is a coil spring body in which the line clearance C between the coil wires 12 is continuous, and the one shown in FIG. 4B is adjacent. The coil dense portion 13 in which the coil wires are in close contact with each other and the coil sparse portion 14 in which there is a clearance C between the wires form a sparse dense coil spring body.
【００２５】そして、図４（Ｃ）に示すものは線間クリ
ヤランスＣを有して「中間部分のコイル径が小にして、
かつ、両端部分のコイル径が大」の「つづみ形コイルば
ね体」に成っている。なお、以上の図４（Ａ）（Ｂ）
（Ｃ）に示すいずれのコイルばね体も、芯線２の曲げ変
形に追従して曲げ変形したときの圧縮変形側のコイル線
間クリアランスＣが、芯線２に予測される「曲げ角度の
総和から導き出される最小曲げ半径においてゼロ（コイ
ル線密着）または微小となる」ように設定されるのが好
ましい。The one shown in FIG. 4 (C) has a clearance C between the wires to "make the coil diameter in the middle portion small,
In addition, it is a "studded coil spring body" in which both ends have a large coil diameter. In addition, the above FIG. 4 (A) (B)
In any of the coil spring bodies shown in (C), the clearance C between the coil wires on the compression deformation side when the bending deformation of the core wire 2 is made by following the bending deformation of the core wire 2 is derived from the "total sum of bending angles" predicted for the core wire 2. It is preferable that the minimum bending radius is zero (coil wire adhesion) or minute.
【００２６】以上の図４実施形態のコイルばね体の造影
マーカーＭから成るものは、線間クリアランスＣに第２
被覆層５の樹脂質が充填されるものの、芯線２が曲げ変
形した時のコイル線１２は、曲げによる圧縮側において
軟質の第１被覆層４に喰い込みながら線間クリアランス
Ｃに存在する第２被覆層５を容易に圧縮して弾性曲り変
形するので、先端部分７の極小曲げ性能が良好に安定す
ると共に、曲げによる応力集中を緩和する。そして、前
記つづみ形コイルばね体はコイル径が大なる両端部位の
曲げ応力が一段と緩和する。The coil spring body, which is composed of the contrast marker M in the embodiment of FIG.
Although the resin material of the coating layer 5 is filled, the coil wire 12 when the core wire 2 is bent and deformed is present in the inter-wire clearance C while biting into the soft first coating layer 4 on the compression side by bending. Since the coating layer 5 is easily compressed and elastically deformed, the minimal bending performance of the tip portion 7 is favorably stabilized and stress concentration due to bending is relaxed. Further, in the above-mentioned coiled coil spring body, the bending stress at both ends where the coil diameter is large is further relieved.
【００２７】そして、その極小曲げ応力が除去される
と、コイルばね体の弾性復元力と前記の弾性圧縮の被覆
層４・５の樹脂質の弾性復元反力によって先端部分７が
ストレート状に速やかに復元する特有作用がある。When the minimal bending stress is removed, the tip end portion 7 is promptly straightened by the elastic restoring force of the coil spring body and the elastic restoring reaction force of the resin material of the coating layers 4 and 5 for elastic compression. There is a special action to restore to.
【００２８】なお、以上の図１〜図４に示すものの偏平
形態の芯線２に円形断面の第１被覆層４を設ける工法
は、例えば芯線２を可溶性ナイロン液に浸漬して偏平部
２Ｃを下向きの縦姿勢にして乾燥させると、横断面長方
形状の偏平部２Ｃ上の該可溶性ナイロン液が自己の表面
張力によって偏平部２Ｃの横断方向に「円形を呈する形
状」に経時変化して乾燥するので、長方形断面の偏平部
２Ｃを埋め込む横断面円形の第１被覆層４が簡便に成形
できる。そして、この第１被覆層４に造影マーカーＭの
円管体を接着固定する。1 to 4, the flat coating 2 is provided with the first coating layer 4 having a circular cross section, for example, by immersing the core 2 in a soluble nylon liquid so that the flat portion 2C faces downward. When dried in the vertical position, the soluble nylon liquid on the flat portion 2C having a rectangular cross section changes with time to a "circular shape" in the transverse direction of the flat portion 2C due to its own surface tension, and then dried. The first coating layer 4 having a circular cross section, which embeds the flat portion 2C having a rectangular cross section, can be easily formed. Then, the circular tube body of the contrast marker M is adhered and fixed to the first coating layer 4.
【００２９】続いて、図５を参照して本発明の他の実施
形態を説明する。即ち、図１実施例と同様な第１・第２
被覆層４・５と短小管形状の造影マーカーＭを有するも
のにおいて、この図５のものは芯線２の偏平部２Ｃを埋
め込んだ第１被覆層４の外周に「偏平部２Ｃと略相似形
の短小長方形管体の造影マーカーＭ」が、２個並設され
ている。Next, another embodiment of the present invention will be described with reference to FIG. That is, the first and second similar to the embodiment of FIG.
In the case where the coating layers 4 and 5 and the contrast marker M in the shape of a short tube are used, the one shown in FIG. 5 has a “similar shape to the flat portion 2C” on the outer periphery of the first coating layer 4 in which the flat portion 2C of the core wire 2 is embedded. Two short and small rectangular tube-shaped contrast markers M ”are arranged in parallel.
【００３０】この図５のものは以下の特有作用がある。
即ち、ガイドワイヤ１を血管内挿入するときは血管患部
の状態視認把握のための造影剤を同時注入すると共に、
血管径路は複雑な立体形状にして該造影剤と造影マーカ
ーＭとの重複等の事情に応じて造影マーカーＭの濃淡・
大小を適宜変更調整するのが好ましいケースがある。こ
のような場合（図５（Ｄ）参照）マーカーＭの大なる長
辺面のＭ１・小なる短辺面のＭ２を映像面に適宜に現わ
してマーカーの大小・濃淡を適宜調整し、映像面による
ガイドワイヤ１の血管内状態の視認把握性の一段の向上
を図ることができる。The one shown in FIG. 5 has the following unique action.
That is, when the guide wire 1 is inserted into a blood vessel, a contrast agent for visually recognizing the state of the affected area of the blood vessel is simultaneously injected, and
The blood vessel path has a complicated three-dimensional shape, and the contrast marker M has a different shade depending on circumstances such as overlap between the contrast agent and the contrast marker M.
In some cases, it is preferable to change and adjust the size as appropriate. In such a case (see FIG. 5D), the large long side M1 of the marker M and the small short side M2 of the marker M are appropriately displayed on the image plane, and the size and shade of the marker are appropriately adjusted to display the image. It is possible to further improve the visual comprehension of the intravascular state of the guide wire 1 by the surface.
【００３１】なお、本発明のガイドワイヤは前記の実施
例に限定されず、先端部分７以外の部分を芯線２の露出
形態（樹脂層不存在）にしたり、図１〜図４実施例の造
影マーカーＭを間隔をおいた２個並設の形態等にするこ
とがある。The guide wire of the present invention is not limited to the above-mentioned embodiment, and the portion other than the distal end portion 7 may have the exposed form of the core wire 2 (without the resin layer), or the contrast of the embodiments of FIGS. There may be a case where two markers M are arranged side by side with an interval.
【００３２】[0032]
【発明の効果】以上の説明のとおり、本発明の医療用ガ
イドワイヤは血管挿入の先導案内として機能する先端部
分の高可撓性・高柔軟性を安定確保し、かつ良好な放射
線造影性を備えた高品質の医療用ガイドワイヤを提供
し、当該血管治療性の向上を図る有用な効果がある。As described above, the medical guide wire of the present invention stably secures high flexibility and high flexibility of the distal end portion which functions as a leading guide for insertion of a blood vessel, and has good radiographic contrast. It is possible to provide a high-quality medical guide wire equipped with the medical instrument and to have a useful effect of improving the blood vessel therapeutic property.
【図１】本発明１実施例の医療用ガイドワイヤを示し、
（Ａ）はその正面断面図、（Ｂ）はその平面断面図、
（Ｃ）はその要部横断面図、（Ｄ）はその作用状態の説
明図FIG. 1 shows a medical guide wire according to an embodiment of the present invention,
(A) is a front sectional view thereof, (B) is a plan sectional view thereof,
(C) is a cross-sectional view of the main part thereof, and (D) is an explanatory view of its operating state.
【図２】図１実施例の態様変化を示し、（Ａ）（Ｂ）は
それぞれの部分正面図2A and 2B show a mode change of the embodiment in FIG. 1, and FIGS. 2A and 2B are front views of respective parts.
【図３】本発明の他の実施例の医療用ガイドワイヤを示
し、（Ａ）（Ｂ）はその部分正面断面図と放射線造影マ
ーカーの斜視図FIG. 3 shows a medical guide wire according to another embodiment of the present invention, in which (A) and (B) are partial front cross-sectional views and perspective views of a radiographic marker.
【図４】本発明の他の実施態様の医療用ガイドワイヤを
示し、（Ａ）（Ｂ）（Ｃ）ともその部分正面断面図FIG. 4 shows a medical guide wire according to another embodiment of the present invention, and (A), (B) and (C) are partial front sectional views thereof.
【図５】本発明の他の実施態様の医療用ガイドワイヤを
示し、（Ａ）はその部分正面断面図、（Ｂ）は（Ａ）の
平面断面図、（Ｃ）は（Ｂ）の横断面図、（Ｄ）はその
作用状態説明図、（Ｅ）はその放射線造影マーカーの斜
視図FIG. 5 shows a medical guide wire according to another embodiment of the present invention, (A) is a partial front sectional view thereof, (B) is a plan sectional view of (A), and (C) is a cross section of (B). A plan view, (D) is an explanatory view of its operating state, and (E) is a perspective view of the radiographic marker.
【図６】従来の医療用ガイドワイヤ示し、（Ａ）（Ｂ）
はその部分正面断面図、（Ｃ）はその放射線不透過マー
カーの斜視図FIG. 6 shows a conventional medical guide wire, (A) and (B).
Is a partial front sectional view thereof, and (C) is a perspective view of the radiopaque marker.
【符号の説明】 １ 医療用ガイドワイヤ ２ 芯線 ２Ｃ 芯線２の偏平部 ３ 樹脂被覆 ４ 第１被覆層 ５ 第２被覆層 ６ 中間被覆層 ７ 先端部分 １０ 係止スリット １１ 係止孔 １２ コイル線 １３ コイル疎部 １４ コイル密部 １５ 従来の医療用ガイドワイヤ Ｃ 線間クリアランス Ｍ 放射線造影マーカー[Explanation of symbols] 1 Medical guide wire 2-core wire 2C Flat part of core wire 2 3 resin coating 4 First coating layer 5 Second coating layer 6 Intermediate coating layer 7 Tip 10 Locking slit 11 locking hole 12 coil wire 13 coil sparse part 14 coil dense part 15 Conventional medical guide wire C Line clearance M radiographic contrast marker
フロントページの続き Ｆターム(参考） 4C167 AA28 BB02 BB08 BB11 BB12 BB13 BB16 BB26 BB31 BB37 BB43 BB63 CC08 GG34 Continued front page F-term (reference) 4C167 AA28 BB02 BB08 BB11 BB12 BB13 BB16 BB26 BB31 BB37 BB43 BB63 CC08 GG34
Claims (8)
ガイドワイヤの先端部分において、前記芯線が偏平形態
にして、前記樹脂被覆が、放射線不透過材不存在の樹脂
層にして、かつ、管状またはコイルばね状の放射線不透
過材から成る放射線造影マーカーを外周に装着した第１
被覆層と、該第１被覆層と該放射線造影マーカーを埋め
込む放射線不透過材存在樹脂層の第２被覆層から成る構
造を特徴とする医療用ガイドワイヤ。1. A medical guide wire comprising a metallic core wire provided with a resin coating, wherein the core wire has a flattened shape, and the resin coating is a resin layer free of a radiopaque material, and A radiographic marker made of a tubular or coil-spring radiopaque material on the outer periphery
A medical guidewire comprising a coating layer, a first coating layer, and a second coating layer that is a radiopaque material-existing resin layer in which the radiographic marker is embedded.
線不透過材不存在の中間被覆層を設けた３層構造から成
る請求項１の医療用ガイドワイヤ。2. The medical guide wire according to claim 1, which has a three-layer structure in which an intermediate coating layer without a radiopaque material is provided between the first coating layer and the second coating layer.
項１または請求項２の医療用ガイドワイヤ。3. The medical guide wire according to claim 1 or 2, wherein the radiographic marker is a tubular body.
たは、管体の周壁に係止孔群を設けた請求項３の医療用
ガイドワイヤ。4. The medical guide wire according to claim 3, wherein a slit formed in the tube length direction of the tubular body or a group of locking holes is provided on the peripheral wall of the tubular body.
横断面長方形状の管体である請求項１または請求項２の
医療用ガイドワイヤ。5. The medical guide wire according to claim 1, wherein the radiographic marker is a tubular body having a rectangular cross section similar to the core wire.
アランスを有するコイルばね体である請求項１または請
求項２の医療用ガイドワイヤ。6. The medical guide wire according to claim 1, wherein the radiographic marker is a coil spring body having a clearance between coil wires.
コイル線間クリアランス存在のコイル疎部とコイル線間
クリアランス不存在のコイル密部の併存から成る請求項
６の医療用ガイドワイヤ。7. The coil spring body of the radiographic marker comprises:
7. The medical guide wire according to claim 6, which comprises a coil sparse portion having a coil wire clearance and a coil dense portion having no coil wire clearance.
つづみばね形態である請求項６または請求項７の医療用
ガイドワイヤ。8. A radiographic marker coil spring body,
The medical guide wire according to claim 6 or 7, which is in the form of a spring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002090150A JP2003284781A (en) | 2002-03-28 | 2002-03-28 | Medical guide wire |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002090150A JP2003284781A (en) | 2002-03-28 | 2002-03-28 | Medical guide wire |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2003284781A true JP2003284781A (en) | 2003-10-07 |
Family
ID=29235514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002090150A Pending JP2003284781A (en) | 2002-03-28 | 2002-03-28 | Medical guide wire |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2003284781A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009514655A (en) * | 2005-11-09 | 2009-04-09 | シー・アール・バード・インコーポレーテッド | Grafts and stent grafts with radiopaque markers |
| JP2009112373A (en) * | 2007-11-02 | 2009-05-28 | Piolax Medical Device:Kk | Guide wire |
| US8313524B2 (en) | 2004-08-31 | 2012-11-20 | C. R. Bard, Inc. | Self-sealing PTFE graft with kink resistance |
| US8652284B2 (en) | 2005-06-17 | 2014-02-18 | C. R. Bard, Inc. | Vascular graft with kink resistance after clamping |
| US9198749B2 (en) | 2006-10-12 | 2015-12-01 | C. R. Bard, Inc. | Vascular grafts with multiple channels and methods for making |
Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4003369A (en) * | 1975-04-22 | 1977-01-18 | Medrad, Inc. | Angiographic guidewire with safety core wire |
| US4571240A (en) * | 1983-08-12 | 1986-02-18 | Advanced Cardiovascular Systems, Inc. | Catheter having encapsulated tip marker |
| JPS6446475A (en) * | 1987-08-17 | 1989-02-20 | Toray Monofilament Co | Guide wire for medical purpose |
| JPH0232849U (en) * | 1988-08-24 | 1990-03-01 | ||
| JPH049162A (en) * | 1990-02-06 | 1992-01-13 | Terumo Corp | Guide wire for catheter |
| JPH05168717A (en) * | 1991-06-18 | 1993-07-02 | Scimed Life Syst Inc | Intravascular guide wire and manufacture thereof |
| JPH1071209A (en) * | 1996-08-29 | 1998-03-17 | Asahi Intec Kk | Guide wire |
| US5910364A (en) * | 1996-07-10 | 1999-06-08 | Asahi Intecc Co., Ltd. | Guide wire and a method of making the same |
| WO1999058183A2 (en) * | 1998-05-14 | 1999-11-18 | Scimed Life Systems, Inc. | High performance coil wire |
| JP2000279531A (en) * | 1999-03-31 | 2000-10-10 | Terumo Corp | Intraluminal indwelling object |
| JP2001137248A (en) * | 1999-11-16 | 2001-05-22 | Olympus Optical Co Ltd | Sampler |
| JP2001212243A (en) * | 2000-02-02 | 2001-08-07 | Ci Medeikku:Kk | Medical guide wire |
| JP2001346884A (en) * | 1993-05-26 | 2001-12-18 | Terumo Corp | Guide wire |
-
2002
- 2002-03-28 JP JP2002090150A patent/JP2003284781A/en active Pending
Patent Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4003369A (en) * | 1975-04-22 | 1977-01-18 | Medrad, Inc. | Angiographic guidewire with safety core wire |
| US4571240A (en) * | 1983-08-12 | 1986-02-18 | Advanced Cardiovascular Systems, Inc. | Catheter having encapsulated tip marker |
| JPS6446475A (en) * | 1987-08-17 | 1989-02-20 | Toray Monofilament Co | Guide wire for medical purpose |
| JPH0232849U (en) * | 1988-08-24 | 1990-03-01 | ||
| JPH049162A (en) * | 1990-02-06 | 1992-01-13 | Terumo Corp | Guide wire for catheter |
| JPH05168717A (en) * | 1991-06-18 | 1993-07-02 | Scimed Life Syst Inc | Intravascular guide wire and manufacture thereof |
| JP2001346884A (en) * | 1993-05-26 | 2001-12-18 | Terumo Corp | Guide wire |
| US5910364A (en) * | 1996-07-10 | 1999-06-08 | Asahi Intecc Co., Ltd. | Guide wire and a method of making the same |
| JPH1071209A (en) * | 1996-08-29 | 1998-03-17 | Asahi Intec Kk | Guide wire |
| WO1999058183A2 (en) * | 1998-05-14 | 1999-11-18 | Scimed Life Systems, Inc. | High performance coil wire |
| JP2002514474A (en) * | 1998-05-14 | 2002-05-21 | サイムド ライフ システムズ， インコーポレイテッド | High performance coil wire |
| JP2000279531A (en) * | 1999-03-31 | 2000-10-10 | Terumo Corp | Intraluminal indwelling object |
| JP2001137248A (en) * | 1999-11-16 | 2001-05-22 | Olympus Optical Co Ltd | Sampler |
| JP2001212243A (en) * | 2000-02-02 | 2001-08-07 | Ci Medeikku:Kk | Medical guide wire |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8313524B2 (en) | 2004-08-31 | 2012-11-20 | C. R. Bard, Inc. | Self-sealing PTFE graft with kink resistance |
| US9572654B2 (en) | 2004-08-31 | 2017-02-21 | C.R. Bard, Inc. | Self-sealing PTFE graft with kink resistance |
| US10582997B2 (en) | 2004-08-31 | 2020-03-10 | C. R. Bard, Inc. | Self-sealing PTFE graft with kink resistance |
| US8652284B2 (en) | 2005-06-17 | 2014-02-18 | C. R. Bard, Inc. | Vascular graft with kink resistance after clamping |
| JP2009514655A (en) * | 2005-11-09 | 2009-04-09 | シー・アール・バード・インコーポレーテッド | Grafts and stent grafts with radiopaque markers |
| JP2013006034A (en) * | 2005-11-09 | 2013-01-10 | C R Bard Inc | Graft and stent graft having radiopaque marker |
| US8636794B2 (en) | 2005-11-09 | 2014-01-28 | C. R. Bard, Inc. | Grafts and stent grafts having a radiopaque marker |
| US9155491B2 (en) | 2005-11-09 | 2015-10-13 | C.R. Bard, Inc. | Grafts and stent grafts having a radiopaque marker |
| US9198749B2 (en) | 2006-10-12 | 2015-12-01 | C. R. Bard, Inc. | Vascular grafts with multiple channels and methods for making |
| JP2009112373A (en) * | 2007-11-02 | 2009-05-28 | Piolax Medical Device:Kk | Guide wire |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7322959B2 (en) | Balloon catheter with radioopaque marker | |
| US20060144408A1 (en) | Micro-catheter device and method of using same | |
| JP2007236472A (en) | Catheter | |
| EP1468707B1 (en) | Guide wire | |
| EP3131616B1 (en) | Helical balloon catheter | |
| EP2421591B1 (en) | Guidewire support system and guidewire | |
| EP1875941A1 (en) | A medical guide wire, an assembly body of the same medical guide wire and microcatheter, an assembly body of the same medical guide wire, a balloon catheter and a guiding catheter | |
| US20190167947A1 (en) | Balloon catheter | |
| JP2003220144A (en) | Guide wire | |
| JP2014233411A (en) | Medical guide wire | |
| WO2012132498A1 (en) | Guide wire for medical use | |
| EP4051361B1 (en) | Guidewires for medical devices | |
| JP4751553B2 (en) | Guiding aid | |
| JP2003284781A (en) | Medical guide wire | |
| JP3184086B2 (en) | catheter | |
| JP2004249095A (en) | Guide wire | |
| CN107224656A (en) | Medical device | |
| JP7137396B2 (en) | guide wire | |
| JP5408727B2 (en) | Medical guidewire | |
| CN217938481U (en) | Blood vessel support | |
| US20220105310A1 (en) | Hollow shaft and catheter | |
| US20210093839A1 (en) | Guide wire | |
| JP3179894U (en) | catheter | |
| JP2006075232A (en) | Wire for removing endovascular foreign body, and medical appliance | |
| JP3091328B2 (en) | Medical guidewire |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20050311 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20070413 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20070424 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20070625 |
|
| RD01 | Notification of change of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7421 Effective date: 20070625 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20070625 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20070903 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20071031 |
|
| A911 | Transfer of reconsideration by examiner before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20071108 |
|
| A912 | Removal of reconsideration by examiner before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A912 Effective date: 20071228 |