JP2003225072A

JP2003225072A - Health supplement having improving action of urinary disturbance

Info

Publication number: JP2003225072A
Application number: JP2002025603A
Authority: JP
Inventors: Suehito Yamagami; 末人山上; Chizuko Yamagami; 千津子山上
Original assignee: Individual
Current assignee: Individual
Priority date: 2002-02-01
Filing date: 2002-02-01
Publication date: 2003-08-12

Abstract

<P>PROBLEM TO BE SOLVED: To provide a health supplement effective for eliminating various causes of urinary disturbance by taking the supplement. <P>SOLUTION: The supplement is a composition composed mainly of ancient vegetable-based drugs originated from foods and obtained by effectively formulating plural components having one or more actions selected from renal function promoting action, antipyretic diuretic action, emmenagogic action, blood cleaning action, cholesterol level depressing action, hypotensive action, hemolytic action, detoxication action, cholagogic action and antibacterial action to increase the synergistic effect and develop the effect for eliminating various causes of urinary disturbance. Concretely, the active components of the supplement are Kouka (flower of Carthemus tinctorium), Suitetsu (dried Hirude nipponica), Rohashi (bean of Sophora alopecuroides), Jifushi (seed of Kochia scoparia), Kinsensou (whole grass of Desmodium styracifolium), Toukishi (seed of Malva verticillata), Sohyosho (ootheca of Hierodule patellifera), Kin-eishi (fruit of Rosa laevigata), Nogikuka (flower of Chrysanthemum indicum), Yakanmon (whole grass of Lespedeza cuneata) and sterol. <P>COPYRIGHT: (C)2003,JPO

Description

【発明の詳細な説明】Detailed Description of the Invention

【０００１】[0001]

【産業上の利用分野】この発明は、頻尿などの尿の排出
障害の改善作用を有する健康補助食品に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a dietary supplement having an effect of improving urinary excretion disorders such as frequent urination.

【０００２】[0002]

【従来の技術】近年、高齢者の増加、糖尿病患者の増加
などにより、尿の排出障害を訴える人が増加している。
男性の前立腺肥大、女性の腹圧性などの尿失禁の増加
は、加齢に伴うやむを得ない現象とも考えられるが、若
い女性に頻尿に悩むものが増えているとの報告もある。
このような尿排出障害は、一般的には他言をはばかり、
一人で悩む場合が多く、適当な治療を受けられないでい
ることが少なくない。しかも、その原因は多岐にわた
り、失禁の原因としては脊髄炎、腹圧性尿失禁、膀胱、
尿道結石、前立腺肥大、起立性低血圧、子宮下垂・下脱
などが、頻尿の原因としては細菌性あるいは糖尿病によ
る腎臓病、膀胱炎、前立腺肥大、更年期障害、子宮発育
不全による病的子宮前傾前屈症などがあげられ、夜尿症
も子供の神経症的障害の他に腎動脈の硬化による場合も
あるとされる。2. Description of the Related Art In recent years, the number of people complaining of urinary excretion disorder has increased due to the increase in the number of elderly people and the number of diabetic patients.
Increased urinary incontinence such as men's prostatic hypertrophy and women's abdominal pressure may be an unavoidable phenomenon with aging, but it is also reported that more young women are suffering from frequent urination.
Such urinary drainage disorders are generally ridiculous,
There are many cases where one person is troubled by himself, and it is often the case that he cannot receive appropriate treatment. Moreover, there are various causes, and the causes of incontinence are myelitis, stress urinary incontinence, bladder,
Urethral stones, benign prostatic hyperplasia, orthostatic hypotension, uterine ptosis / prolapse, etc. Inclination and flexion are included, and nocturnal enuresis is also thought to be due to hardening of the renal arteries in addition to neurological disorders in children.

【０００３】[0003]

【発明が解決しようとする問題点】上記のように排尿障
害の原因は多岐にわたり、自覚症状が明らかな場合もあ
るとは言え、ビタミン欠乏、自律神経失調など、本人に
は自覚することの難しい原因も多く、それらの症状に対
して原因除去のための適切な医薬や健康補助食品の選択
を行うことは困難な場合も多い。このような事情に鑑
み、本発明は、その摂取によって広範にわたる排尿障害
の原因の除去に効果のある健康補助食品を得ようとする
ものである。[Problems to be Solved by the Invention] As described above, there are various causes of dysuria, and although subjective symptoms may be obvious, it is difficult for the person to notice such as vitamin deficiency and autonomic imbalance. There are many causes, and it is often difficult to select an appropriate medicine or health supplement for eliminating the causes for those symptoms. In view of such circumstances, the present invention seeks to obtain a health supplement that is effective in eliminating a wide range of causes of dysuria by ingestion.

【０００４】[0004]

【課題を解決するための手段】上記目的を達成するため
の本発明の健康補助食品は、古来の食品由来の天然物を
主成分とする組成物であり、そのおもな薬効成分は以下
の通りである。紅花、水蛭、蘆巴子、地膚子、金銭草、
冬葵子、桑ひょう蛸、金纓子、野菊花、夜関門、および
ステロールMeans for Solving the Problems The dietary supplement of the present invention for achieving the above object is a composition containing a natural product derived from an ancient food as a main component, and its main medicinal components are as follows. On the street. Safflower, fluke, 蘆跴子, ground silk, coins,
Fuyu Aoi, Kuwa Hyo octopus, Kinko, No chrysanthemum, Yakanmon, and Sterol

【０００５】上記本発明の健康補助食品に配合される成
分は、それぞれ、以下の薬効を持つとされる（主として
難波恒雄著「和漢薬百科図鑑」による。）。紅花紅色・黄色色素の他、リグナン、ベニバナ
油、ステロールを含み、血管収縮作用、子宮や腸管の興
奮作用が認められ、婦人病、冷え症、更年期障害などの
血行障害の治療に用いられ、また、アテローム性動脈硬
化症の予防と治療に有効とされる。水蛭鬱血部の吸血に用いることはよく知られてい
るが、水、アルコールエキスには血液凝固抑制作用、溶
血作用があり、お血除去、通経など、血行障害の治療に
用いられる。蘆巴子地中海原産の豆科植物で、ギリシャ・ローマ
時代から既に薬用として用いられた。薬理作用は未詳で
あるが、滋養、緩和、駆風薬として、腎臓虚冷、小腹冷
痛、寒湿脚気などに用いられる。地膚子アカザ科のホウキギの果実であり、サポニン
を含むとされるが詳細は未詳である。しかし、膀胱経に
入り、熱を清め、よく淋を通じ、毒を消し、小便を利す
るとされ、小便不利、水腫、脚気などに用いられる。金銭草まめ科の植物で、成分、薬理作用は未詳であ
るが、臨床的に利胆作用、静熱利水作用があり、胆嚢結
石、尿道結石に効果があるとされる。冬葵子アオイ科のイチビの種子を乾燥したもので、
成分、薬理作用は未詳であるが、二便の通利をよくし、
催乳、消腫の効があるとして小便不利、水腫に用いられ
る。桑ひょう蛸カマキリの卵鞘で、肝腎を補い、精気を
益し、陽を壮んにするといわれ、頻尿、尿失禁、夜尿症
の他、産後の遺尿、帯下、めまいにもよいとされる。金纓子バラ科のナニワイバラの成熟果実と花托を乾
燥したもので、リンゴ酸などの有機酸、精油、ビタミン
Ｃ、サポニンを含むといわれるがその薬理作用は未詳で
ある。強壮、収斂、止瀉薬として、遺尿、頻尿、夜尿症
に用いられる。野菊花解熱作用、毛細血管増強作用の他、グラム陰
性腸内病原菌に対する抑制作用があり、また、血圧降下
作用も見られる。風熱を除き、肝を益し、目を明らかに
するといわれ、動脈硬化、高コレステロール症などに用
いられる。夜関門マメ科のメドハギの全草であり、ピニトー
ル、フラボノイド、タンニン、およびβ−シトステロー
ルなどを含み、肝腎を補い、お血を散らし、腫れを消す
とされる。利尿、尿失禁、夜尿症によいとされる。ステロール植物ステロールはヨーロッパにおいては
古くから民間療法として前立腺肥大症の治療薬として使
用されており、わが国においても臨床研究の結果、その
有効性が認められている（泌尿紀要４４：８６５頁，１
９９８）。The ingredients contained in the dietary supplement of the present invention are said to have the following medicinal effects (mainly according to Tsuneo Namba "Encyclopedia of Japanese and Chinese Medicine"). Safflower In addition to crimson and yellow pigments, it contains lignans, safflower oil, and sterols, and has vasoconstrictor effects, uterine and intestinal excitatory effects, and is used for the treatment of blood circulation disorders such as gynecological diseases, chills, and menopause. It is effective in the prevention and treatment of atherosclerosis. Although it is well known that it is used for sucking blood in the confluent part of water flukes, water and alcohol extracts have blood coagulation suppressing action and hemolytic action, and are used for treating blood circulation disorders such as blood removal and menstruation. Tomoko This legume is native to the Mediterranean Sea and has already been used for medicinal purposes since the Greek and Roman times. Although its pharmacological action is unknown, it is used as a nourishing, palliative, carminative agent for renal chills, cold abdominal pain, cold / wet beriberi and the like. Jinjiko This is a fruit of Houkigi from the family Azaraceae, which is said to contain saponins, but the details are unknown. However, it is said to enter the urinary bladder, cleanse the heat, often through gonorrhea, eliminate poison, and benefit from urine, which is used for urine disadvantage, edema, and beriberi. It is a botanical plant, whose composition and pharmacological actions are unknown, but it has clinically biliary action, hydrothermal and hydrostatic action, and is said to be effective for gallbladder stones and urethral stones. Winter Aoi This is a dried seed of the Abutilonaceae
The ingredients and pharmacological actions are unknown, but it improves the convenience of two flights,
It is used for lactation, edema, and edema due to its effectiveness in lactation and anti-tumor. It is said to be an egg sheath of mulberry octopus praying mantis, which supplements the liver and kidneys, improves vitality, and makes the sun more intense. . The dried fruit and flower buds of Naniwaibara, a member of the family Rosaceae, are said to contain organic acids such as malic acid, essential oils, vitamin C and saponin, but their pharmacological actions are unknown. Used as a tonic, astringent, antidiarrheal for enuresis, frequent urination, and nocturnal enuresis. Nonchrysanthemum In addition to antipyretic and capillary enhancing effects, it also has an inhibitory effect on Gram-negative enteric pathogens and also has a blood pressure lowering effect. It is said that it removes wind and heat, benefits the liver, and reveals the eyes, and is used for arteriosclerosis, hypercholesterolemia, etc. It is a whole plant of Meadhaghi, a family of legumes, and contains pinitol, flavonoids, tannins, β-sitosterol, etc., and it is said to supplement hepatic kidneys, dissipate blood, and eliminate swelling. Good for diuresis, urinary incontinence, and nocturnal enuresis. Sterols Plant sterols have long been used as folk remedies for the treatment of benign prostatic hyperplasia in Europe, and their efficacy has been confirmed as a result of clinical studies in Japan (Urine Bulletin 44: 865, 1
998).

【０００６】上記のように、排尿障害の原因は多岐にわ
たり、中には自覚されない原因も少なくない。にもかか
わらず、排尿障害、特に重度でない場合には、そのため
に病院を訪れることも少なく、自己診断に頼って自覚出
来る原因にのみ作用する成分を含む薬剤あるいは健康補
助食品を摂取しても、それだけで十分な効果を得ること
難しい。このような排尿障害の特徴に鑑み、原因として
存在する可能性の高い症状を広く改善出来る組成物を摂
取することが望ましい。本発明では、上記の有効作用を
有する各成分を、紅花３〜８重量％、水蛭６〜１６重量
％、蘆巴子１０〜２５重量％、地膚子６〜１６重量％、
金銭草１２〜３２重量％、冬葵子６〜１６重量％、桑ひ
ょう蛸３〜８重量％、金纓子６〜１６重量％、野菊花１
０〜２５重量％、夜関門８〜２０重量％、ステロール１
２〜３５重量％、残部が賦形剤である配合割合で配合し
てある。本発明の健康補助食品が改善作用を持つ排尿障
害の原因および効果が期待される主な症状は表１の通り
である。[0006] As described above, there are various causes of dysuria, and there are many causes that are not recognized. Nevertheless, urinary disorders, especially when not severe, rarely visits the hospital for that reason, and even if you take a drug or health supplement containing a component that acts only on the cause that you can recognize by relying on self-diagnosis, It's difficult to get enough effect. In view of such characteristics of dysuria, it is desirable to take a composition capable of widely improving symptoms that are likely to be the cause. In the present invention, each of the components having the above-mentioned effective effects is obtained by adding 3 to 8% by weight of safflower, 6 to 16% by weight of fluke, 10 to 25% by weight of spinach, and 6 to 16% by weight of ground silk.
Golden grass 12-32% by weight, winter aoi 6-6% by weight, mulberry octopus 3-8% by weight, golden dust 6-16% by weight, wild chrysanthemum 1
0-25% by weight, night barrier 8-20% by weight, sterol 1
2 to 35% by weight and the balance is an excipient. Table 1 shows the causes of dysuria and the main symptoms for which the effects are expected to have the improving effect of the dietary supplement of the present invention.

【０００７】[0007]

【表１】 [Table 1]

【０００８】[0008]

【発明の実施の態様】上記の各組成物は、主として漢方
生薬ないしエキスとして薬種店で容易に入手可能であ
り、賦形剤と共に錠剤とするのが最も望ましい。その配
合形態および配合比を示せば以下の通りである。以下の
％は全て重量％である。配合例紅花３〜８％水蛭６〜１６％蘆巴子１０〜２５％地膚子６〜１６％金銭草１２〜３２％冬葵子６〜１６％桑ひょう蛸３〜８％金纓子６〜１６％野菊花１０〜２５％夜関門８〜２０％ステロール１２〜３５％賦形剤１８〜２０％本発明の健康食品の摂取量は最低限１,５００mg／日、
最大限２,２５０mg／日の範囲であることが望ましい。BEST MODE FOR CARRYING OUT THE INVENTION Each of the above-mentioned compositions is mainly available as a Chinese herbal medicine or an extract at a drug store, and it is most preferable to make a tablet together with an excipient. The blending form and blending ratio are shown below. All the following percentages are weight percentages. Formulation example Safflower 3-8% Water leech 6-16% Tomoeko 10-25% Ground silk 6-16% Money grass 12-32% Winter aoi 6-16% Kuwahyo octopus 3-8% Kinko 6-16 % No chrysanthemum 10-25% Night barrier 8-20% Sterol 12-35% Excipient 18-20% Intake of the health food of the present invention is at least 1,500 mg / day,
It is desirable that the maximum range is 2,250 mg / day.

【０００９】[0009]

【実施例】実施例１紅花９．０ mg 水蛭１８．０ mg 蘆巴子２７．０ mg 地膚子１８．０ mg 金銭草３６．０ mg 冬葵子１８．０ mg 桑ひょう蛸９．０ mg 金纓子１８．０ mg 野菊花２７．０ mg 夜関門１８ mg ステロール２７ mg 賦形剤２５ mg 計２５０ mg この実施例は、１日３回、食前または食間に服用するた
めのもので、毎回２錠ずつ服用すれば１,５００mg／
日、３錠ずつ服用すれば２,２５０mg／日となる。[Examples] Example 1 Safflower 9.0 mg Hydrangea 18.0 mg Riko Tomoko 27.0 mg Ground silk 18.0 mg Coinweed 36.0 mg Winter Aoi 18.0 mg Mulberry Hook octopus 9.0 mg Kinko 18.0 mg Nokikuhana 27.0 mg Night barrier 18 mg Sterol 27 mg Excipient 25 mg Total 250 mg This example is to be taken 3 times a day before or between meals, 2 times each time. 1,500 mg / if taken in tablets
If you take 3 tablets daily, the dose will be 2,250 mg / day.

【００１０】実施例２紅花１０．５ mg 水蛭２１．０ mg 蘆巴子３１．５ mg 地膚子２１．０ mg 金銭草４２．０ mg 冬葵子２１．０ mg 桑ひょう蛸１０．５ mg 金纓子２１．０ mg 野菊花３１．５ mg 夜関門２０．０ mg ステロール３０．０ mg 賦形剤４０．０ mg 計３００ mg この実施例は、１日３回、食前または食間に服用するた
めのもので、毎回２錠ずつ服用すれば１,８００mg／
日、３錠ずつ服用すれば２,７００mg／日となる。 Example 2 safflower 10.5 mg hydrangea 21.0 mg 蘆芆子 31.5 mg ground skin 21.0 mg coin grass 42.0 mg winter aoi 21.0 mg mulberry octopus 10.5 mg gold Fuso 21.0 mg Nokiku flower 31.5 mg night gate 20.0 mg sterol 30.0 mg excipient 40.0 mg total 300 mg This example is intended to be taken three times daily, before or between meals. If you take 2 tablets each time, it will be 1,800mg /
If you take 3 tablets each day, the dose will be 2,700 mg / day.

【００１１】使用例上記実施例２の錠剤を表２に示す頻尿又は失禁等の症状
を有する５人に１日９錠〜１２錠を投与し、その治癒効
果を確認した。その結果、表２に示すように何れの症例
においても著しい効果が確認された。Example of Use The tablets of Example 2 above were administered 9 to 12 tablets per day to 5 persons having symptoms such as urinary frequency or incontinence shown in Table 2, and their healing effects were confirmed. As a result, as shown in Table 2, a remarkable effect was confirmed in all cases.

【表２】 [Table 2]

【００１２】[0012]

【発明の効果】本発明の排尿障害の改善作用を有する健
康補助食品は、上記のように、失禁、頻尿等の排尿障害
の改善に著しい効果が認められ、且つ植物系生薬を中心
とするものであるので、毒性、副作用の恐れもなく、従
来にない優れた健康補助食品を得ることができたもので
ある。As described above, the dietary supplement of the present invention having the action of improving urinary disorders has a remarkable effect on the improvement of urinary disorders such as incontinence and frequent urination, and is mainly composed of botanical herbs. Therefore, it is possible to obtain an unprecedented excellent dietary supplement without fear of toxicity and side effects.

───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.⁷ 識別記号ＦＩテーマコート゛(参考）Ａ６１Ｋ 35/78 Ａ６１Ｋ 35/78 ＨＪＴＡ６１Ｐ 13/00 Ａ６１Ｐ 13/00 (72)発明者山上千津子東京都中野区中央４−26−10 東豊マンション704号Ｆターム(参考） 4B018 LB10 MD61 ME14 4C086 AA01 AA02 DA11 MA03 MA04 MA07 MA52 NA05 ZA81 4C087 AA01 AA02 BB12 BB21 MA02 MA52 NA05 ZA81 4C088 AB12 AB13 AB26 AB51 AB59 MA08 MA52 NA05 ZA81 ─────────────────────────────────────────────────── ─── Continuation of front page (51) Int.Cl. ⁷ Identification code FI theme code (reference) A61K 35/78 A61K 35/78 HJT A61P 13/00 A61P 13/00 (72) Inventor Chizuko Yamagami Tokyo 4-26-10 Chuo, Nakano-ku, Tohyo Mansion No. 704, F-term (reference) 4B018 LB10 MD61 ME14 4C086 AA01 AA02 DA11 MA03 MA04 MA07 MA52 NA05 ZA81 4C087 AA01 AA02 BB12 BB21 MA02 MA52 NA05 ZA81 4C088 AB12 AB13 MA26 AB51 AB51 AB26 AB51 AB51 AB26 MA52 NA05 ZA81

Claims

【特許請求の範囲】[Claims]

【請求項１】紅花、水蛭、蘆巴子、地膚子、金銭草、
冬葵子、桑ひょう蛸、金纓子、野菊花、夜関門、および
ステロールを有効成分とすることを特徴とする排尿障害
の改善作用を有する健康補助食品。1. Safflower, water flies, 蘆巴子, ground silk, coins,
A health supplement having an action of improving urination disorder, which is characterized by having Fuyu Aoi, mulberry octopus, Kinko, No chrysanthemum, Yakanmon, and sterol as active ingredients.

【請求項２】各成分の配合比は、紅花３〜８重量％、
水蛭６〜１６重量％、蘆巴子１０〜２５重量％、地膚子
６〜１６重量％、金銭草１２〜３２重量％、冬葵子６〜
１６重量％、桑ひょう蛸３〜８重量％、金纓子６〜１６
重量％、野菊花１０〜２５重量％、夜関門８〜２０重量
％、ステロール１２〜３５重量％、残部が賦形剤である
ことを特徴とする請求項１の排尿障害の改善作用を有す
る健康補助食品。2. The mixing ratio of each component is 3 to 8% by weight of safflower,
6 to 16% by weight of hydrangea, 10 to 25% by weight of 蘆跆子, 6 to 16% by weight of ground silk, 12 to 32% by weight of coins, 6 to winter aoi
16% by weight, mulberry octopus 3-8% by weight, gold duster 6-16
%, Nogiku flowers 10 to 25% by weight, night barrier 8 to 20% by weight, sterols 12 to 35% by weight, and the balance is excipients. Supplements.