JP2002165864A - Method for manufacturing multiple-chamber container - Google Patents
Method for manufacturing multiple-chamber containerInfo
- Publication number
- JP2002165864A JP2002165864A JP2000369912A JP2000369912A JP2002165864A JP 2002165864 A JP2002165864 A JP 2002165864A JP 2000369912 A JP2000369912 A JP 2000369912A JP 2000369912 A JP2000369912 A JP 2000369912A JP 2002165864 A JP2002165864 A JP 2002165864A
- Authority
- JP
- Japan
- Prior art keywords
- container
- chamber
- joint
- joining
- divided
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Package Specialized In Special Use (AREA)
- Bag Frames (AREA)
- Making Paper Articles (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は分割容器を接合する
ことにより複室容器を製造する方法、特に分割容器毎に
異なる処理を施すのに好適な複室容器の製造方法に関す
る。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for manufacturing a multi-chamber container by joining divided containers, and more particularly to a method for manufacturing a multi-chamber container suitable for performing different treatments for each divided container.
【０００２】[0002]
【従来の技術】医療、化粧品、食品等の分野において、
容器周囲を密封するとともに、容易に剥離できる程度の
弱シール部により容器内部を複数の収容室に仕切った合
成樹脂製可撓性複室容器が多用されている。このような
容器では、使用時まで複数の収容室に収容物をそれぞれ
隔離した状態で密封して収容しておき、使用時に弱シー
ル部を剥離することにより複数の収容室を連通させ、こ
れにより各収容室の内容物を外気に晒すことなく混合し
て使用することができるようになっている。近年、この
ような複室容器として、弱シール部により仕切られた収
容室を有する２つの分割容器を接合して、該弱シール部
を剥離することにより各容器の収容室間が連通されるよ
うに構成されたものが提案されている。このような容器
では、各分割容器毎に異なる材料を用いて製造すること
ができ、また別々に充填したり、滅菌処理する等、別々
の処理を施すことができるため、各収容室に異なる収容
物を収容する場合に製造し易いという利点を有してい
る。2. Description of the Related Art In the fields of medicine, cosmetics, foods, and the like,
2. Description of the Related Art A flexible multi-chamber container made of a synthetic resin, in which the periphery of a container is sealed and the inside of the container is partitioned into a plurality of storage chambers by a weak seal portion that can be easily peeled, is often used. In such a container, the contents are sealed and stored in a plurality of storage rooms in a state of isolation until use, and the plurality of storage rooms are communicated by peeling off the weak seal portion during use, thereby The contents of each accommodation room can be mixed and used without being exposed to the outside air. In recent years, as such a multi-chamber container, two divided containers each having a storage chamber partitioned by a weak seal portion are joined, and the weak seal portion is peeled off to allow communication between the storage chambers of the containers. Has been proposed. Such containers can be manufactured using different materials for each of the divided containers, and can be separately filled or sterilized, so that different treatments can be performed. It has the advantage that it is easy to manufacture when storing things.
【０００３】このような容器を製造するには、例えば、
特開平９−１０２８２号及び特開平９−１０２８３号で
は、分割容器の一部に、収容室を区画する剥離可能な弱
シール部と該弱シール部から更に延長する易滅菌用接続
部とを設け、一方の分割容器の易滅菌用接合部を他方の
分割容器の易滅菌用接合部内に挿入して溶着することに
より２つの分割容器を接合している。また、特開平８−
２１５２８５号では、弱シール形成用シートを挟んで溶
着することにより分割容器の一端に弱シール部を形成
し、弱シール形成用シートに溶着されていない一方の分
割容器の容器壁と弱シール形成用シートに溶着されてい
る他方の分割容器の容器壁とを重ねて弱シール部同士で
溶着して２つの分割容器を接合している。しかしなが
ら、このような複室容器では、分割容器を接合するまで
は接合部分の容器壁が、弱シール部より外側に配置され
て互いに溶着されずに当接した状態となっているため容
器外部との仕切がなく、それぞれの分割容器に別々に充
填、滅菌等の処理を施すと、この溶着されていない容器
壁間に異物が侵入する可能性がある。この容器壁間は、
分割容器を接合して複室容器とした後は、使用時の連通
路となる部分であり、万一、製造時にこの部分に異物が
侵入すると、使用時に収容物に異物が混入することにな
るという不都合が生じる。To manufacture such a container, for example,
In Japanese Patent Application Laid-Open Nos. 9-10282 and 9-10283, a part of a divided container is provided with a peelable weak seal portion that divides a storage chamber and a connection portion for easy sterilization that further extends from the weak seal portion. The two divided containers are joined by inserting and welding the easily sterilized joint of one divided container into the easily sterilized joint of the other divided container. Further, Japanese Unexamined Patent Publication No.
In Japanese Patent No. 215285, a weak seal portion is formed at one end of a divided container by sandwiching a weak seal forming sheet therebetween, and the weak seal forming portion is not welded to the weak seal forming sheet. The two divided containers are joined by overlapping the container wall of the other divided container welded to the sheet and welding with the weak seal portions. However, in such a multi-chamber container, until the divided containers are joined, the joint wall is arranged outside the weak seal portion and is in a state of being in contact with each other without being welded to each other. If each divided container is separately filled and sterilized, etc. without any partition, foreign matter may enter between the unwelded container walls. Between the container walls,
After joining the divided containers to form a multi-chamber container, it is a part that becomes a communication path during use, and if foreign matter enters this part at the time of manufacture, foreign matter will mix into the container at the time of use Inconvenience occurs.
【０００４】[0004]
【発明が解決しようとする課題】本発明はこのような従
来の問題点を解決するため、分割容器の接合部分を清浄
に維持することができ、収容物への異物の混入を確実に
防止することができる複室容器の製造方法を提案するこ
とを目的とする。SUMMARY OF THE INVENTION In order to solve the above-mentioned conventional problems, the present invention makes it possible to keep the junction of the divided containers clean and to surely prevent foreign matters from being mixed into the contents. It is an object of the present invention to propose a method of manufacturing a multi-chamber container which can be used.
【０００５】[0005]
【課題を解決するための手段】上記目的を達成する本発
明の複室容器の製造方法は、剥離可能な弱シール部で仕
切られた収容室を有する複数の分割容器を接合してな
り、前記弱シール部を剥離することにより前記分割容器
の収容室間が連通可能な複室容器を製造する方法におい
て、周囲を密封するとともに内部に前記弱シール部を形
成して前記収容室及び接合部形成室を形成する工程と、
前記接合部形成室の一部を切除して前記弱シール部から
延長した接合部を形成することにより少なくとも１つの
前記分割容器を形成する工程と、該分割容器の接合部を
他の分割容器と液密に接合する工程とを含むことを特徴
とする。A method of manufacturing a multi-chamber container according to the present invention, which achieves the above object, comprises joining a plurality of divided containers each having a storage chamber partitioned by a peelable weak seal portion. In a method of manufacturing a multi-chamber container in which the storage chambers of the divided containers can communicate with each other by peeling the weak seal portion, the surrounding chamber is sealed and the weak seal portion is formed inside to form the storage chamber and the joint portion. Forming a chamber;
Forming at least one of the divided containers by cutting off a part of the joint forming chamber to form a joint extending from the weak seal portion; and joining the joint of the divided containers with another divided container. And a step of joining in a liquid-tight manner.
【０００６】本発明の製造方法によれば、周囲を密封す
るとともに内部に弱シール部を形成して収容室及び接合
部形成室を形成し、その後、接合部形成室の一部を切除
して弱シール部から延長した接合部を形成するようにし
たので、予め清浄な状態で接合部形成室を形成しておけ
ば、その後接合部を形成するまでの間に分割容器を外気
に露出させたり、分割容器に各種の処理を施しても、接
合部形成室の内部を清浄に維持することができる。その
ため、接合時に接合部形成室の一部を切除して接合部を
形成しても接合部の内部は清浄な状態であり、この部分
において分割容器を接合して、使用時に収容物とこの接
合部の内部とが接触しても、収容物に異物が混入するこ
とはない。特に、本発明において複室容器が医療用容器
であって、収容室及び接合部形成室の形成後接合部形成
前に少なくとも１つの分割容器を滅菌処理する工程を含
むものであると、特に好適である。即ち、医療用容器で
は内部が極めて高度に清浄であることが要求されるが、
接合部が密封されていない状態で、分割容器の収容室と
接合部とを滅菌すると、滅菌処理雰囲気中に存在する微
粒子等の異物が直接接合部内に侵入してしまう可能性が
ある。ところが本発明ではこの滅菌処理時に接合部を接
合部形成室として密封しているので、接合部の内部が直
接滅菌処理雰囲気と接触することがなく、接合部内部に
異物が侵入する可能性がないのである。なお、本発明で
は、分割容器の接合後に接合部を照射滅菌処理するよう
にすれば、接続部形成室を切除した後接続部を接合する
までの間の僅かな時間に接合部内に外気が侵入して微生
物汚染を受けたとしても、この接続部の内部を滅菌する
ことができてより安全であり、しかも、接合部内には収
容物が存在しないため、他の収容室に影響を与えにくい
照射滅菌を施すことができるので、滅菌処理が容易であ
る。According to the manufacturing method of the present invention, the periphery is sealed and a weak seal portion is formed inside to form a housing chamber and a joint forming chamber, and then a part of the joint forming chamber is cut off. Since the joint part extended from the weak seal part is formed, if the joint part formation chamber is formed in advance in a clean state, the divided container can be exposed to the outside air before the joint part is formed. Even if various treatments are performed on the divided container, the inside of the joint forming chamber can be kept clean. Therefore, even if a joint is formed by cutting off a part of the joint forming chamber at the time of joining, the inside of the joint is in a clean state. Even if the inside of the section comes into contact, foreign matter does not enter the stored item. In particular, in the present invention, it is particularly preferable that the multi-chamber container is a medical container and includes a step of sterilizing at least one of the divided containers after forming the storage chamber and the joint forming chamber and before forming the joint. . In other words, the inside of a medical container is required to be extremely highly clean,
If the joint chamber is sterilized in a state where the joint is not hermetically sealed, the foreign matter such as fine particles present in the sterilization atmosphere may directly enter the joint. However, in the present invention, since the joint is sealed as a joint forming chamber during the sterilization process, the inside of the joint does not directly come into contact with the sterilization processing atmosphere, and there is no possibility that foreign matter enters the inside of the joint. It is. In the present invention, if the joint is irradiated and sterilized after the joining of the divided containers, outside air can enter the joint for a short time after the connection forming chamber is cut off and before the connection is joined. Even if microbial contamination occurs, the inside of this connection can be sterilized and it is safer.Because there is no stored material in the joint, irradiation is less likely to affect other storage rooms. Since sterilization can be performed, sterilization processing is easy.
【０００７】[0007]
【発明の実施の形態】以下、本発明の実施形態を説明す
る。図１は、本発明の１実施形態を適用して得られた医
療用輸液を収容する容器を示す正面図、図２（ａ）〜
（ｃ）は本発明の製造工程を説明するための図である。
この複室容器１０は、剥離可能な弱シール部３により仕
切られた第１の収容室１ａを有する第１の容器１と剥離
可能な弱シール部３により仕切られた第２の収容室を有
する第２の容器２とが、それぞれ弱シール部３から延長
した接合部５をそれぞれ接合部材６に溶着することによ
り接合して形成されている。そして、この複室容器１０
を使用するには、第１又は第２の収容室１ａ、２ａを外
側から押圧する等により内圧を上昇させて剥離可能な弱
シール部３を剥離して、第１及び第２の収容室１ａ、２
ａ間を連通させ、各収容室の内容物を混合して排出口７
から排出させることにより使用することができる。Embodiments of the present invention will be described below. FIG. 1 is a front view showing a container for containing a medical infusion obtained by applying one embodiment of the present invention, and FIGS.
(C) is a figure for explaining the manufacturing process of the present invention.
The multi-chamber container 10 has a first container 1 having a first storage chamber 1 a partitioned by a peelable weak seal portion 3 and a second storage chamber partitioned by a peelable weak seal portion 3. The second container 2 is formed by welding the joining portions 5 extending from the weak seal portions 3 to the joining members 6 respectively. And this double chamber container 10
In order to use the first and second storage chambers 1a and 2a, the internal pressure is increased by pressing the first or second storage chambers 1a and 2a from the outside, and the peelable weak seal portion 3 is peeled off. , 2
a, and the contents of each accommodation chamber are mixed and discharged.
It can be used by discharging from
【０００８】このような複室容器１０を、本実施形態に
より製造するには、次のようにして行う。まず、図２
（ａ）に示すような第１または第２の収容室１ａ、２ａ
を有する容器１２を形成する。初めに、容器壁材料の内
面を対向させた状態で周囲を密封する。ここでは、合成
樹脂製のチューブ状材料の上下両端を剥離不能に強シー
ルして密封部１３ａ、１３ｂを形成している。このとき
密封部１３ａは、混注口または排出口７を配置した状態
で密封することができる。この密封部の形成方法は、例
えばチューブ状材料の内壁面を構成する層が十分に溶融
される温度に加熱してシールしてもよい。なおこのチュ
ーブ状材料の内壁面は予め清浄に形成されているのが好
ましい。これと同時に、または前若しくは後に、容器内
部に剥離可能な弱シール部３を形成して収容室１ａ、２
ａと接続部形成室１５とを液密に仕切る。この弱シール
部３の形成方法としては、例えば、チューブ状材料の内
壁面を構成する層が完全に溶融される温度より低く、ま
た、前記強シールのシール温度より低い温度で加熱して
シールしてもよい。In order to manufacture such a multi-chamber container 10 according to the present embodiment, the following procedure is performed. First, FIG.
1st or 2nd accommodation room 1a, 2a as shown in (a)
Is formed. First, the periphery is sealed with the inner surfaces of the container wall material facing each other. Here, the sealing portions 13a and 13b are formed by strongly sealing the upper and lower ends of the synthetic resin tubular material so as not to peel off. At this time, the sealing portion 13a can be sealed with the co-injection port or the discharge port 7 arranged. In the method of forming the sealing portion, for example, the sealing may be performed by heating to a temperature at which the layer constituting the inner wall surface of the tubular material is sufficiently melted. It is preferable that the inner wall surface of the tube-shaped material is formed clean in advance. At the same time, or before or after, a peelable weak seal portion 3 is formed inside the container, and the storage chambers 1a, 2
a and the connection portion forming chamber 15 are liquid-tightly partitioned. As a method of forming the weak seal portion 3, for example, the sealing is performed by heating at a temperature lower than the temperature at which the layer constituting the inner wall surface of the tubular material is completely melted, and at a temperature lower than the sealing temperature of the strong seal. You may.
【０００９】次に、混注口または排出口７から、収容物
を必要に応じて収容室に収容し、混注口または排出口７
を密封する。この例では、第１の収容室１ａを有する容
器１２には何も収容せず、第２の収容室２ａを有する容
器１２には薬液を収容し、図１（ａ）に示すような容器
１２を製造する。そして、この状態で容器１２を滅菌処
理する。ここでは、第１の収容室１ａを有する容器１２
は、内容物が収容されていない状態で紫外線、電子線、
キセノンパルス等の照射により照射滅菌処理し、第２の
収容室２ａを有する容器１２は、薬液が収容された状態
でオートクレーブにより高圧蒸気滅菌処理を行う。この
とき、第２の収容室２ａを有する容器１２は配管やオー
トクレーブ等の内部に存在する微粒子等の異物を同伴し
た状態の水蒸気や水滴等と接触するが、該容器１２の外
周は密封されているので、収容室２ａや接合部形成室１
５内には容器壁を透過した純粋な水蒸気だけが侵入し、
異物が侵入することはない。その後、第１の収容室１ａ
に、第２の収容室２ａの薬液と混合或いは溶解するため
の薬剤を無菌充填により収容する。なお、粉末を充填す
る場合には、前記チューブ状材料の周囲の一部が密封さ
れる前に収容しておくことも可能である。Next, the contents are accommodated in the accommodating chamber from the co-injection port or the discharge port 7 if necessary,
Seal. In this example, nothing is stored in the container 12 having the first storage chamber 1a, and a drug solution is stored in the container 12 having the second storage chamber 2a, and the container 12 shown in FIG. To manufacture. Then, the container 12 is sterilized in this state. Here, the container 12 having the first storage chamber 1a
Means that no ultraviolet light, electron beam,
The container 12 having the second storage chamber 2a is subjected to high-pressure steam sterilization by an autoclave in a state in which the liquid medicine is stored in the container 12, which is irradiated with xenon pulses or the like. At this time, the container 12 having the second storage chamber 2a comes into contact with water vapor, water droplets, or the like in a state accompanied by foreign matter such as fine particles present inside the pipe or the autoclave, but the outer periphery of the container 12 is sealed. The housing chamber 2a and the joint forming chamber 1
Only pure water vapor that has permeated the container wall penetrates into 5,
No foreign matter enters. Then, the first accommodation room 1a
Next, a drug for mixing or dissolving with the drug solution in the second storage chamber 2a is stored by aseptic filling. In addition, when the powder is filled, it is also possible to store the tubular material before a portion around the tubular material is sealed.
【００１０】次に、図２（ｂ）に示すように、容器１２
の接合部形成室１５を一部切除して、分割容器１、２を
形成する。この切除により、互いに溶着されることなく
当接した状態の接合部形成室１５の内壁面が容器端部に
配置され、この部分が接合部５となる。そして、図２
（ｃ）に示すように、第１の分割容器１と第２の分割容
器２とをそれぞれ接合部５、５同士を対向させて、両分
割容器１、２の接合部５、５の外周の全周囲を接合部材
６で覆い、各接合部５、５の外表面と接合部材６の内表
面とを接合する。ここでは、接合部材６として、合成樹
脂により筒状に形成された成形体を用いていて、この筒
状の接合部材６内に各分割容器の接合部５、５を挿入
し、それぞれ、両者の間を剥離不能に溶着したり、接着
する等により接合している。この分割容器の接合は前記
接合部５を形成後に連続的に行うのが好ましく、また、
接合部５の形成から分割容器の接合までの間を無菌状態
で行うのが好ましい。Next, as shown in FIG.
Is partially cut off to form the divided containers 1 and 2. By this cutting, the inner wall surface of the joint forming chamber 15 in a state where the joints are in contact with each other without being welded to each other is arranged at the end of the container. And FIG.
As shown in (c), the first divided container 1 and the second divided container 2 are joined with their joints 5 and 5 facing each other, and the outer periphery of the joints 5 and 5 of the two divided containers 1 and 2 is formed. The entire periphery is covered with the joining member 6, and the outer surfaces of the joining portions 5 and 5 and the inner surface of the joining member 6 are joined. Here, a molded article formed of a synthetic resin into a cylindrical shape is used as the joining member 6, and the joining portions 5, 5 of the divided containers are inserted into the tubular joining member 6. The gaps are joined by non-peelable welding or bonding. The joining of the divided containers is preferably carried out continuously after the joining portion 5 is formed.
It is preferable to perform the process from the formation of the joint portion 5 to the joining of the divided containers under aseptic conditions.
【００１１】なお、この接合部５及び接合部材６の大き
さは、適宜、選択できるが、次のようにするのが好まし
い。接合部５の幅Ｗ１は、使用時に内容物が接合部５内
を流動するので内部を流動し易くして混合を容易にする
ために広いほど好ましく、接合部形成室１５の全幅とす
るのが好適である。また、分割容器の接合部５の長さＬ
は、接合部材６と接合可能な長さとするが、接合部材６
の内側に第１の容器１の接合部５と第２の容器２の接合
部５とを対向した状態で配置して溶着する際、両容器の
接合部５が平面的な安定した形状を保持できる長さとす
るのが好ましい。なお、接合部材６の形状は、シート
状、帯状等の任意の形状であってもよいが、筒状の形状
であれば取扱が容易で好ましい。この場合、接合部材６
の幅Ｗ３は、前記接合部５を構成する容器壁の全幅Ｗ２
以上にする必要があり、接合部材６の内部に接合部５を
挿入し易くするため、全幅Ｗ２の１．０５倍以上の幅と
するのが好適である。このように第１の分割容器１と第
２の分割容器２とを接合後、この実施形態では、両分割
容器１、２の接合部５、５及び接合部材６により囲まれ
た接続部分を照射滅菌処理して、その内部を十分に滅菌
している。この照射滅菌の方法としては、例えば５０〜
５００ｋＶの加速電圧の低エネルギー型の電子線を照射
することにより、或いは２００ｗ〜１０００ｗの高出力
紫外線を照射することにより、更にはキセノンパルスを
照射することにより行うことができる。Although the size of the joining portion 5 and the joining member 6 can be appropriately selected, the following is preferred. The width W1 of the joint portion 5 is preferably wider as the content flows in the joint portion 5 during use, so that the content can easily flow inside and facilitate mixing, and the width W1 is preferably the entire width of the joint portion forming chamber 15. It is suitable. In addition, the length L of the joint 5 of the divided container
Is a length that can be joined to the joining member 6.
When the joint portion 5 of the first container 1 and the joint portion 5 of the second container 2 are arranged and welded to each other inside the joint, the joint portion 5 of the two containers maintains a planar stable shape. Preferably, the length is as long as possible. In addition, the shape of the joining member 6 may be any shape such as a sheet shape or a band shape, but a cylindrical shape is preferable because it is easy to handle. In this case, the joining member 6
Is the total width W2 of the container wall forming the joint portion 5.
It is necessary to make the width more than 1.05 times the total width W2 in order to facilitate the insertion of the joint portion 5 inside the joint member 6. After the first divided container 1 and the second divided container 2 are joined in this manner, in this embodiment, the connection portion surrounded by the joints 5, 5 and the joint member 6 of the two divided containers 1, 2 is irradiated. It is sterilized and the inside is sufficiently sterilized. As a method of this irradiation sterilization, for example, 50-
The irradiation can be performed by irradiating a low-energy electron beam with an acceleration voltage of 500 kV, or by irradiating high-power ultraviolet rays of 200 w to 1000 w, or by irradiating a xenon pulse.
【００１２】以上のようにして複室容器を製造すれば、
周囲を密封するとともに内部に弱シール部３を形成して
接合部形成室１５を形成し、その後、接合部形成室１５
の一部を切除して弱シール部３から延長した接合部５を
形成するようにしたので、予め清浄な状態で接合部形成
室１５を形成しておけば、その後接合部５を形成するま
での間に分割容器１、２を外気に露出させたり、分割容
器１、２に各種の処理を施しても、接合部形成室１５の
内部を清浄に維持することができる。そのため、接合部
形成室１５の一部を切除して接合部５を形成すれば内部
が清浄な状態の接合部５が得られ、この接合部５におい
て分割容器１、２を接合して複室容器１０を製造し、使
用時に弱シール部３を剥離して接合部５内に収容物を流
動させて接触させても、収容物に異物が混入することは
ない。また、このように収容室２ａ及び接合部形成室１
５の形成後接合部５の形成前に分割容器２の滅菌処理を
行って医療用容器を製造すると、滅菌処理時に接合部５
が接合部形成室１５として密封されているので、接合部
５の内部が直接滅菌処理雰囲気と接触することがなく、
接合部５内部が医療用容器に要求されるような高度の清
浄状態に維持でき、使用時に収容物に異物が混入する可
能性がない。さらに、分割容器１、２の接合後に接合部
５全体を照射滅菌処理すると、接続部形成室１５を切除
した後接合するまでの間の僅かな時間に接合部５内に外
気が直接侵入して微生物汚染を受けたとしても、この接
合部５の内部を滅菌することができる。このとき接合部
５内に何も収容物が存在しないため、照射滅菌が容易で
あるとともに、照射滅菌であるため他の収容室１ａ、２
ａに影響を与えることがなくて好ましい。If a multi-chamber container is manufactured as described above,
The periphery is sealed, and the weak seal portion 3 is formed therein to form a joint forming chamber 15. Thereafter, the joint forming chamber 15 is formed.
Is cut off to form the joint portion 5 extending from the weak seal portion 3. If the joint portion forming chamber 15 is formed in a clean state in advance, the joint portion 5 is formed thereafter. Even if the divided containers 1 and 2 are exposed to the outside air or various processes are performed on the divided containers 1 and 2, the interior of the joint forming chamber 15 can be kept clean. Therefore, if a part of the joint forming chamber 15 is cut off to form the joint 5, the joint 5 having a clean inside can be obtained, and the divided containers 1 and 2 are joined at the joint 5 to form a double chamber. Even if the container 10 is manufactured and the weak seal portion 3 is peeled off during use and the contents are allowed to flow into and come into contact with the joining portion 5, no foreign matter is mixed into the contents. Further, as described above, the accommodation chamber 2a and the joint forming chamber 1
If the medical container is manufactured by sterilizing the divided container 2 before forming the joint 5 after the formation of the joint 5,
Is sealed as the joint forming chamber 15, so that the inside of the joint 5 does not directly come into contact with the sterilization atmosphere.
The inside of the joint portion 5 can be maintained in a high degree of cleanness required for a medical container, and there is no possibility that foreign matter may be mixed into the container during use. Further, if the entire joint 5 is irradiated and sterilized after the divided containers 1 and 2 are joined, outside air directly enters the joint 5 in a short time until the joint is formed after the joint forming chamber 15 is cut off. Even if it is subjected to microbial contamination, the inside of the joint 5 can be sterilized. At this time, since there is no stored material in the joint portion 5, irradiation sterilization is easy, and since irradiation sterilization is performed, the other storage chambers 1a, 2
This is preferable because it does not affect a.
【００１３】なお、上記実施形態では、接合部同士を接
合部材を介して接合する例を説明したが、接合部同士を
直接、例えば一方の接合部を他方の接合部に挿入して溶
着するなどにより、接合するようにしてもよい。この場
合、少なくとも１方の分割容器の接続部の幅は他方の分
割容器の接続部を構成する容器壁の全幅以上にするのが
好ましい。また、分割容器の両方に接合部形成室或いは
接合部を形成した例を説明したが、いずれか一方の容器
に設けるものであっても、本発明は適用可能である。さ
らに、上記では、各シールを溶着により形成している
が、他の方法であってもよく、接着などにより行うこと
も可能である。また、上記では、弱シール部を形成する
場合に、対向する容器内壁を直接溶着しているが、例え
ば、容器内壁間に弱シール形成用の他の部材を介在させ
たり、容器壁を多層構造の材料を用いて層間に接合強度
が低下する層を介在させて形成してもよい。また、上記
実施形態では、分割容器として何れも１つの収容室を有
する例を説明したが、複数の収容室を有するものであっ
ても、接合部と少なくとも１つの収容室とが弱シール部
により仕切られている分割容器であれば、全く同様に本
発明を適用することができる。また、各収容室の形状も
何ら限定されず、周囲が弱シールからなる４角形、円
形、楕円等の形状であってもよい。なお、本発明が適用
される複室容器は、従来より弱シール部を有する複室容
器に使用されているポリオレフィン系樹脂等の樹脂材料
を用いて形成したが、これに限定されるものではなく、
他の非樹脂材料を含む材料を用いてもよい。In the above-described embodiment, an example in which the joining portions are joined via the joining member has been described. However, the joining portions are directly welded, for example, by inserting one joining portion into the other joining portion and welding. May be used for joining. In this case, the width of the connecting portion of at least one of the divided containers is preferably equal to or greater than the entire width of the container wall forming the connecting portion of the other divided container. Further, the example in which the joint forming chamber or the joint is formed in both of the divided containers has been described. However, the present invention is applicable to a case where the joint forming chamber or the joint is provided in either one of the containers. Further, in the above description, each seal is formed by welding, but another method may be used, and the seal may be performed by adhesion or the like. In the above description, when the weak seal portion is formed, the inner walls of the container facing each other are directly welded. However, for example, another member for forming a weak seal is interposed between the inner walls of the container, or the container wall has a multilayer structure. It may be formed by using the above material and interposing a layer whose bonding strength is reduced between the layers. Further, in the above-described embodiment, the example in which each of the divided containers has one storage chamber is described. However, even if the divided container has a plurality of storage chambers, the joint portion and at least one storage chamber are formed by the weak seal portion. The present invention can be applied in the same manner as long as the divided containers are partitioned. Further, the shape of each storage chamber is not limited at all, and may be a shape such as a quadrangle, a circle, an ellipse, etc., whose periphery is made of a weak seal. Note that the multi-chamber container to which the present invention is applied is formed using a resin material such as a polyolefin-based resin that has been conventionally used for a multi-chamber container having a weakly sealed portion, but is not limited thereto. ,
A material including another non-resin material may be used.
【００１４】[0014]
【発明の効果】以上詳述の通り、本発明によれば、 剥
離可能な弱シール部で仕切られた収容室を有する複数の
分割容器を接合して複室容器を製造する際、周囲を密封
するとともに内部に弱シール部を形成して収容室及び接
合部形成室を形成する工程と、接合部形成室の一部を切
除して弱シール部から延長した接合部を形成する工程
と、該接合部を用いて複数の分割容器を液密に接合する
工程とを含むので、分割容器の接合部分を接合直前まで
清浄に維持することができ、収容物への異物の混入を確
実に防止することができる。As described in detail above, according to the present invention, when manufacturing a multi-chamber container by joining a plurality of divided containers having storage chambers separated by a peelable weak seal portion, the periphery is sealed. Forming a weak seal portion inside to form a housing chamber and a joint forming chamber, and removing a part of the joint forming chamber to form a joint extending from the weak seal portion. And a step of joining a plurality of divided containers in a liquid-tight manner using the joining portion, so that the joined portions of the divided containers can be kept clean until immediately before joining, and the foreign matter is reliably prevented from being mixed into the container. be able to.
【図１】本発明の製造方法により製造した複室容器を示
す正面図である。FIG. 1 is a front view showing a multi-chamber container manufactured by a manufacturing method of the present invention.
【図２】（ａ）〜（ｃ）は図１の複室容器を製造する工
程を説明する図である。FIGS. 2 (a) to 2 (c) are views for explaining steps of manufacturing the multi-chamber container of FIG.
１ 第１の容器 １ａ 第１の収容室 ２ 第２の容器 ２ａ 第２の収容室 ３ 弱シール部 ５ 接合部 ６ 接合部材 ７ 混注口または排出口 １０ 複室容器 １２ 製造途中の容器 １３ａ、１３ｂ 密封部 １５ 接合部形成室 DESCRIPTION OF SYMBOLS 1 1st container 1a 1st accommodating chamber 2 2nd container 2a 2nd accommodating chamber 3 Weak seal part 5 Joining part 6 Joining member 7 Co-injection or discharge port 10 Double chamber container 12 Container 13a, 13b under manufacture Sealing part 15 Joint forming chamber
───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.7 識別記号 ＦＩ テーマコート゛(参考） Ｂ３１Ｂ 27/00 Ｂ６５Ｄ 81/32 Ｄ Ｂ６５Ｄ 30/22 Ａ６１Ｊ 1/00 ３３０Ｂ 81/32 ３５１Ａ ──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. 7 Identification symbol FI Theme coat ゛ (Reference) B31B 27/00 B65D 81/32 D B65D 30/22 A61J 1/00 330B 81/32 351A
Claims (5)
室を有する複数の分割容器を接合してなり、前記弱シー
ル部を剥離することにより前記分割容器の収容室間が連
通可能な複室容器を製造する方法において、 周囲を密封するとともに内部に前記弱シール部を形成し
て前記収容室及び接合部形成室を形成する工程と、 前記接合部形成室の一部を切除して前記弱シール部から
延長した接合部を形成することにより少なくとも１つの
前記分割容器を形成する工程と、 該分割容器の接合部を他の分割容器と液密に接合する工
程と を含むことを特徴とする複室容器の製造方法。A plurality of divided containers each having a storage chamber partitioned by a peelable weak seal portion are joined, and the storage container of the divided container can be communicated by peeling the weak seal portion. A method of manufacturing a chamber container, wherein a step of sealing the periphery and forming the weak seal portion inside to form the housing chamber and the joint forming chamber; and cutting off a part of the joint forming chamber Forming a joining portion extending from the weak seal portion to form at least one of the divided containers; and joining the joined portion of the divided container to another divided container in a liquid-tight manner. Method of manufacturing a multi-chamber container.
し、該接合部間を液密に接合する請求項１に記載の複室
容器の製造方法。2. The method for producing a multi-chamber container according to claim 1, wherein the joints are formed in the plurality of divided containers, and the joints are joined in a liquid-tight manner.
記収容室及び接合部形成室の形成後前記接合部形成前に
滅菌処理する工程を含む請求項１または２に記載の複室
容器の製造方法。3. The multi-chamber according to claim 1, wherein the multi-chamber container is a medical container, and includes a step of performing a sterilization process after the formation of the storage chamber and the joint forming chamber and before the formation of the joint. Container manufacturing method.
室に内容物を収容する工程を含む請求項３記載の複室容
器の製造方法。4. The method for producing a multi-chamber container according to claim 3, further comprising the step of storing the contents in the storage chamber of the divided container before the sterilizing step.
部の照射滅菌処理工程を含む請求項３または４に記載の
複室容器の製造方法。5. The method for producing a multi-chamber container according to claim 3, further comprising an irradiation sterilization step of the joint portion after joining the plurality of divided containers.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000369912A JP2002165864A (en) | 2000-12-05 | 2000-12-05 | Method for manufacturing multiple-chamber container |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000369912A JP2002165864A (en) | 2000-12-05 | 2000-12-05 | Method for manufacturing multiple-chamber container |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2002165864A true JP2002165864A (en) | 2002-06-11 |
Family
ID=18839876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000369912A Pending JP2002165864A (en) | 2000-12-05 | 2000-12-05 | Method for manufacturing multiple-chamber container |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2002165864A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008150096A (en) * | 2006-12-20 | 2008-07-03 | Dainippon Printing Co Ltd | Packaging bag with spout and its manufacturing method |
| US7789852B2 (en) | 2004-11-26 | 2010-09-07 | Hosokawa Yoko Co., Ltd. | Medical liquid container and preparation-containing medical liquid container |
| JP2019034767A (en) * | 2017-08-17 | 2019-03-07 | 藤森工業株式会社 | Multiple-chambered container |
| JP2021104342A (en) * | 2015-06-16 | 2021-07-26 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ Ｖｅｔｍｅｄｉｃａ ＧｍｂＨ | Connecting and container system |
| US11649104B2 (en) | 2015-06-16 | 2023-05-16 | Boehringer Ingelheim Vetmedica Gmbh | Connecting and container system |
| US11992461B2 (en) | 2015-06-16 | 2024-05-28 | Boehringer Ingelheim Vetmedica Gmbh | Connecting and container system |
-
2000
- 2000-12-05 JP JP2000369912A patent/JP2002165864A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7789852B2 (en) | 2004-11-26 | 2010-09-07 | Hosokawa Yoko Co., Ltd. | Medical liquid container and preparation-containing medical liquid container |
| JP2008150096A (en) * | 2006-12-20 | 2008-07-03 | Dainippon Printing Co Ltd | Packaging bag with spout and its manufacturing method |
| JP2021104342A (en) * | 2015-06-16 | 2021-07-26 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ Ｖｅｔｍｅｄｉｃａ ＧｍｂＨ | Connecting and container system |
| JP7206311B2 (en) | 2015-06-16 | 2023-01-17 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | Connection and vessel system |
| US11649104B2 (en) | 2015-06-16 | 2023-05-16 | Boehringer Ingelheim Vetmedica Gmbh | Connecting and container system |
| US11992461B2 (en) | 2015-06-16 | 2024-05-28 | Boehringer Ingelheim Vetmedica Gmbh | Connecting and container system |
| JP2019034767A (en) * | 2017-08-17 | 2019-03-07 | 藤森工業株式会社 | Multiple-chambered container |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3016348B2 (en) | Double chamber container | |
| EP0345774B1 (en) | Filled container | |
| US5462526A (en) | Flexible, sterile container and method of making and using same | |
| RU2196536C2 (en) | Flexible reservoir with a set of divisions for storing medicaments and method of its manufacturing | |
| US6718735B2 (en) | Albumin in a flexible polymeric container | |
| JP2008273631A (en) | Albumin in flexible polymeric container | |
| US6484874B1 (en) | Medical container with multiple chambers and method of producing the same | |
| RU2558829C2 (en) | Filling of containers | |
| JP2002165864A (en) | Method for manufacturing multiple-chamber container | |
| AU2002254196A1 (en) | Albumin in a flexible polymeric container | |
| JP5104884B2 (en) | Method for producing medical drug enclosure and container therefor | |
| KR101177290B1 (en) | Method of Producing and Filling a Sheet-Material Bag | |
| JP4341015B2 (en) | Method for manufacturing multi-chamber container with easy-open contents | |
| JP4768898B2 (en) | Method for producing medical drug enclosure and container therefor | |
| JP2003104302A (en) | Manufacturing method of bag for liquid | |
| JP4239198B2 (en) | Small volume mixed injection container and multi-bag using the same | |
| JPH10218252A (en) | Container for storing multi-constituent | |
| JPH08215285A (en) | Production of double-chamber container | |
| JPH0639018A (en) | Container for medial treatment | |
| JP2003205977A (en) | Flexible multi-chamber container | |
| JP3517919B2 (en) | Medical containers and molding dies | |
| JPH10201820A (en) | Container for medical treatment | |
| JP2002331019A (en) | Method for manufacturing double-chamber container | |
| JP2003093475A (en) | Medicine filling device, medicine filling method and method of manufacturing for medicine bag containing medicine | |
| JPH09135881A (en) | Medical container with germfree connection part |