JP2002103096A - Tabletting machine - Google Patents
Tabletting machineInfo
- Publication number
- JP2002103096A JP2002103096A JP2000303789A JP2000303789A JP2002103096A JP 2002103096 A JP2002103096 A JP 2002103096A JP 2000303789 A JP2000303789 A JP 2000303789A JP 2000303789 A JP2000303789 A JP 2000303789A JP 2002103096 A JP2002103096 A JP 2002103096A
- Authority
- JP
- Japan
- Prior art keywords
- molded product
- die
- wall
- lower punch
- fine powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/0082—Dust eliminating means; Mould or press ram cleaning means
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Description
【０００１】[0001]
【発明が属する技術分野】この発明は，錠剤などを圧縮
成形する，打錠機に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a tablet press for compressing tablets and the like.
【０００２】[0002]
【従来の技術】打錠機を長時間運転していると，成形物
のバルク強度が低下してくる。これを放置したまま運転
を続けると，成形物を押上げ排出するときや，成形物の
搬送中に成形物が破壊し，収率が低下するという問題が
ある。このため，成形物を大量に生産したいときは，成
形物のバルク強度が低下してくるたびに，いったん運転
を中止し，打錠機を分解し，杵および臼を洗浄したの
ち，再び組み立てる，という作業が必要である。よっ
て，打錠機については，終夜で連続運転したり，無人運
転したりという省力化を推進することが困難であるとい
う問題がある。2. Description of the Related Art When a tableting machine is operated for a long time, the bulk strength of a molded product is reduced. If the operation is continued with this being left as it is, there is a problem that the molded product is destroyed when the molded product is pushed up and discharged or during the transportation of the molded product, and the yield is reduced. For this reason, when mass production of molded products is desired, the operation is stopped once, the tableting machine is disassembled, the punches and dies are washed, and then reassembled each time the bulk strength of the molded products decreases. It is necessary to work. Therefore, the tableting machine has a problem that it is difficult to promote labor saving such as continuous operation overnight or unmanned operation.
【０００３】[0003]
【発明が解決しようとする課題】長時間にわたり連続し
て運転を続けても，成形物のバルク強度が低下してこな
いような打錠機を提供することを課題とした。SUMMARY OF THE INVENTION An object of the present invention is to provide a tableting machine in which the bulk strength of a molded product does not decrease even if the operation is continued for a long time.
【０００４】[0004]
【課題を解決するための手段】まず，成形物のバルク強
度が低下してくる原因について，次のように考察した。
打錠機を運転するとき，打錠用顆粒に含まれる微粉末，
または打錠用顆粒が成形途中で破壊されることにより発
生する微粉末が，下杵側面と臼内壁の隙間に入り込む。
さらに運転を続けると，下杵の上下運動により，下杵側
面と臼内壁にこすり付けられた打錠用顆粒が固着し，下
杵側面と臼内壁の隙間は閉塞する。すると，打錠用顆粒
の粒子間に含まれていた空気は，圧縮工程において逃げ
場を失い，成形物の内部に高圧な気泡として含有され
る。この気泡は成形物を内部から破壊するストレスを有
するため，成形物のバルク強度が低下する。成形物のバ
ルク強度が低下すると，後に述べるように排出過程で破
損が発生しやすくなったり，輸送時に摩耗または破損が
発生しやすくなる。ところで，圧縮工程では成形物を上
下から圧縮する力の一部が，成形物を横方向に広げる力
として作用する。その力は臼に伝わり，臼を横方向へ押
し広げる。横方向に弾性膨張した臼が，抜圧後に元の大
きさに戻ろうとしても，臼が弾性膨張した状態において
成形過程を終えた成形物が，臼の弾性収縮を妨げる。こ
の弾性的な復元力は，成形物側面と臼内壁との垂直抗力
として作用する。さて，臼内壁において打錠用顆粒が固
着しているとき，成形物側面と臼内壁との摩擦係数が大
きくなるから，先に延べた垂直抗力とにより，成形物を
押し上げ排出するときに大きな摩擦力が発生する。この
とき，成形物内部に含まれる高圧の気泡により成形物の
バルク強度が低下していることもあり，排出工程におい
て成形物は臼内壁から受けるせん断応力に耐えきれず破
壊しやすい。次に，課題を解決するための具体的な手段
を，次のように考えた。従来，いったん打錠機を組み立
ててしまうと，下杵側面は，ずっと臼内に収まったまま
である。このため，いちど下杵側面と臼内壁の隙間に入
り込んだ微粉末は自然に排出されることはない。下杵側
面と臼内壁の隙間に入り込んだ微粉末は，下杵の上下運
動よってこすられるうちに固着し，この隙間を閉塞させ
てしまう。そこで微粉末を積極的に除去するにはどうし
たら良いかを考えることにした。微粉末が固着する前の
ほうが容易に除去できることと，打錠機の一連の動作に
組み込んでしまえば除去作業のためだけに運転を停止し
なくてもすむこととから，圧縮サイクルごとに除去する
方法を選んだ。基本的な手段は，打錠用顆粒を圧縮成形
したあと，下杵側面に付着した打錠用顆粒を除去するた
め，下杵側面を露出させることである。このとき重力な
どの作用により，下杵側面および臼内壁に付着した微粉
末の一部が落下する。しかしながらさらに，ブラシ等を
下杵側面または臼内壁に接触させたり，圧縮空気などを
下杵側面または臼内壁に吹き付けて，付着した微粉末を
積極的にかき落とすといっそう効果がある。なお，この
圧縮空気に滑沢剤を混合しておけば，外部滑沢剤の添加
工程と，微粉末の除去工程を兼ねることができる。下杵
側面を露出させるには，下杵を臼の下方へ抜き取るか，
臼の上方へ突き出して露出させる。あるいは，成形物を
押上げて排出する代わりに，臼を左右または上下に割り
開いて成形物を取り出し，下杵側面または臼内壁を清掃
することも効果がある。さらに，杵の圧縮面について
も，ブラシや圧縮空気等により清掃すれば，杵の圧縮面
での打錠用顆粒の堆積を妨げる効果があるから，成形物
が杵の圧縮面に付着しにくくなり，スティッキングなど
の打錠障害までも抑制することができる。ここまでは，
下杵側面と臼内壁の隙間について述べたが，上杵側面と
臼内壁の隙間にも微粉末が固着するおそれはある。現実
には，重力などの効果によって微粉末が入り込む機会が
少ないこと，成形物を押上げ排出するときに臼内壁の上
部は成形物の側面によりこすられるから微粉末は成形物
と一緒に排出されること，および上杵側面は圧縮工程ご
とに臼の外に露出するから微粉末は自然に落下する機会
があることなどの効果により，固着のおそれは少ない。
必要なときは，上杵側面と臼内壁においても，下杵側面
と臼内壁と同様な対策を行うことにより，そこでの固着
を抑制できる。First, the cause of the decrease in the bulk strength of a molded product was considered as follows.
When operating a tableting machine, fine powder contained in granules for tableting,
Alternatively, the fine powder generated by breaking the granules for tableting during molding enters the gap between the side surface of the lower punch and the inner wall of the die.
When the operation is further continued, the tableting granules rubbed on the side surface of the lower punch and the inner wall of the die are fixed by the vertical movement of the lower punch, and the gap between the side surface of the lower punch and the inner wall of the die is closed. Then, the air contained between the particles of the tableting granules loses its escape in the compression step, and is contained as high-pressure bubbles inside the molded product. Since these bubbles have a stress that breaks the molded product from the inside, the bulk strength of the molded product is reduced. When the bulk strength of the molded product is reduced, as described later, breakage is likely to occur in the discharging process, and wear or breakage is likely to occur during transportation. By the way, in the compression step, a part of the force for compressing the molded product from above and below acts as a force for expanding the molded product in the lateral direction. The force is transmitted to the mortar, pushing the mortar laterally. Even if the die elastically expanded in the lateral direction attempts to return to the original size after the pressure is released, the molded product that has completed the molding process in a state where the die is elastically expanded prevents the elastic contraction of the die. This elastic restoring force acts as a vertical reaction between the side surface of the molded product and the inner wall of the die. When the granules for tableting adhere to the inner wall of the die, the friction coefficient between the side surface of the molded product and the inner wall of the die becomes large. Force is generated. At this time, the bulk strength of the molded product may be reduced due to high-pressure bubbles contained in the molded product, and the molded product cannot withstand the shear stress received from the inner wall of the die during the discharging process, and is easily broken. Next, we considered the specific means to solve the problems as follows. Conventionally, once the tableting machine has been assembled, the side surface of the lower punch remains in the die all the time. Therefore, the fine powder that has entered the gap between the side surface of the lower punch and the inner wall of the die is not discharged naturally. The fine powder entering the gap between the side surface of the lower punch and the inner wall of the die is fixed while being rubbed by the vertical movement of the lower punch, and closes the gap. Therefore, we decided to consider how to positively remove fine powder. It is removed every compression cycle because it can be removed more easily before the fine powder is fixed, and if it is incorporated into a series of operations of the tableting machine, it is not necessary to stop the operation just for the removal operation. I chose the method. The basic means is to expose the lower punch side in order to remove the tablet granules attached to the lower punch side after compressing the tablet granules. At this time, due to the action of gravity or the like, a part of the fine powder attached to the side surface of the lower punch and the inner wall of the die falls. However, it is more effective to bring a brush or the like into contact with the side surface of the lower punch or the inner wall of the die or to blow compressed air or the like onto the side surface of the lower punch or the inner wall of the die to actively scrape off the attached fine powder. If a lubricant is mixed with the compressed air, the step of adding the external lubricant and the step of removing the fine powder can be combined. To expose the side surface of the lower punch, pull out the lower punch below the die,
Protrude above the mortar to expose. Alternatively, instead of pushing up and discharging the molded product, it is also effective to split the die horizontally or vertically and take out the molded product and clean the side surface of the lower punch or the inner wall of the die. Furthermore, cleaning the compressed surface of the punch with a brush or compressed air has the effect of preventing the accumulation of granules for tableting on the compressed surface of the punch, so that the molded product is less likely to adhere to the compressed surface of the punch. Also, tableting troubles such as sticking can be suppressed. So far,
Although the gap between the side surface of the lower punch and the inner wall of the mortar has been described, fine powder may adhere to the gap between the side surface of the upper punch and the inner wall of the mortar. In reality, there are few opportunities for fine powder to enter due to the effects of gravity and the like. When pushing up and discharging a molded product, the upper part of the inner wall of the die is rubbed by the side of the molded product, so the fine powder is discharged together with the molded product. In addition, the side surface of the upper punch is exposed to the outside of the mortar in each compression process, so that there is a chance that the fine powder falls naturally, so that there is little danger of sticking.
When necessary, the same measures can be taken on the side surface of the upper punch and the inner wall of the die as well as on the side surface of the lower punch and the inner wall of the die, so that the fixation there can be suppressed.
【０００５】[0005]
【作用】固着が進行する前に下杵側面または臼内壁をブ
ラシ等により清掃することにより，微粉末が固着し，ま
た固着層が成長することを抑制できる。つまり打錠用顆
粒の微粉末が固着して，下杵側面と臼内壁の隙間を閉塞
することを抑制できる。下杵側面と臼内壁の隙間の固着
がなくなると，打錠用顆粒の粒子間に含まれていた空気
は，圧縮工程に抜け出ることができるから，成形物の内
部に高圧な気泡が含有されることがなくなる。さらに成
形物と臼内壁との摩擦係数が小さいから，成形物と臼内
壁間の摩擦力も小さくなり，成形物を押上げ排出すると
きに破損しにくくなる。もちろん，臼を割り開いて成形
物を取り出すときは，押上げ排出による摩擦力が発生し
ないから，成形物は破損しない。The fine powder is fixed and the growth of the fixed layer can be suppressed by cleaning the side surface of the lower punch or the inner wall of the die with a brush or the like before the fixing proceeds. That is, it is possible to prevent the fine powder of the granules for tableting from sticking and closing the gap between the side surface of the lower punch and the inner wall of the die. When the gap between the lower punch side and the inner wall of the die disappears, the air contained between the granules for tableting can escape to the compression process, and high-pressure bubbles are contained inside the molded product Disappears. Further, since the coefficient of friction between the molded product and the inner wall of the die is small, the frictional force between the molded product and the inner wall of the die is also reduced, and the molded product is less likely to be damaged when pushed up and discharged. Of course, when the die is split open and the molded product is taken out, the molded product is not damaged because no frictional force is generated by pushing up and discharging.
【０００６】[0006]
【実施例】圧縮成形ののち下杵を下方に引き抜いて露出
させ，滑沢剤を含む圧縮空気を臼上方から吹きつけ，上
杵側面，上杵圧縮面，臼内壁，下杵圧縮面，および下杵
側面に付着した打錠用顆粒を吹き飛ばして清掃する機構
の例を図１に示す。EXAMPLE After compression molding, the lower punch was pulled down and exposed, and compressed air containing a lubricant was blown from above the die, and the upper punch side surface, upper punch compression surface, die inner wall, lower punch compression surface, and FIG. 1 shows an example of a mechanism for blowing and cleaning the granules for tableting attached to the side surface of the lower punch.
【０００７】[0007]
【発明の効果】下杵側面および臼内壁に，固着する打錠
用顆粒を取り除くことにより，圧縮工程での打錠用顆粒
からの脱気が容易となり，成形物内に高圧の気泡が含有
されず，したがって成形物のバルク強度が低下しない。
しかも，成形物と臼内壁との摩擦力が小さくなるから，
成形物が押し上げ排出されるときに破損しない。臼を割
り開いて成形物を取り出すときは，押上げをしないので
成形物は摩擦力を受けることが無く，破損しにくい。圧
縮空気を用いて清掃するとき，外部滑沢剤の添加工程と
兼ねることができるが，外部滑沢剤を用いた成形物のバ
ルク強度は高いから，滑沢剤を含む圧縮空気を用いて清
掃すれば，いっそう成形物の破損を抑制できる。さらに
下杵または上杵の圧縮面の清掃を兼ねることも容易であ
るから，先に述べたように成形物の破損を抑制できるほ
か，圧縮面への打錠用顆粒の付着に起因するスティッキ
ングなどの打錠障害を抑制することができる。EFFECT OF THE INVENTION By removing the granules for tableting adhered to the side surface of the lower punch and the inner wall of the die, degassing from the granules for tableting in the compression step becomes easy, and high-pressure bubbles are contained in the molded product. Therefore, the bulk strength of the molded product does not decrease.
In addition, the frictional force between the molding and the inner wall of the die becomes smaller,
Does not break when the molded product is pushed up and discharged. When the mortar is opened and the molded product is taken out, the molded product is not subjected to frictional force because it is not pushed up, so that the molded product is not easily damaged. When cleaning with compressed air, it can also serve as the step of adding an external lubricant, but since the bulk strength of the molded article using the external lubricant is high, cleaning with compressed air containing a lubricant is used. By doing so, it is possible to further suppress breakage of the molded product. Furthermore, since it is easy to clean the compressed surface of the lower punch or upper punch as well, it is possible to prevent the molded product from being damaged as described above, as well as sticking due to the sticking of tablet granules to the compressed surface. Tableting trouble can be suppressed.
【図１】圧縮工程，除去工程，および除去後の様子を示
す縦断面図。FIG. 1 is a longitudinal sectional view showing a compression step, a removal step, and a state after removal.
１上杵 ２臼 ３下杵 ４外部滑沢剤を含有する圧縮空気およびその吹き出し口 ５成形物 ６付着した打錠用顆粒 1 Upper punch 2 Mill 3 Lower punch 4 Compressed air containing external lubricant and its outlet 5 Molded product 6 Attached granules for tableting
Claims (1)
どを清掃する機構を有する打錠機。1. A tableting machine having a mechanism for cleaning a side surface of a lower punch, an inner wall of a die, or a compressed surface of a punch.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000303789A JP2002103096A (en) | 2000-10-03 | 2000-10-03 | Tabletting machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000303789A JP2002103096A (en) | 2000-10-03 | 2000-10-03 | Tabletting machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2002103096A true JP2002103096A (en) | 2002-04-09 |
Family
ID=18784943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000303789A Pending JP2002103096A (en) | 2000-10-03 | 2000-10-03 | Tabletting machine |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2002103096A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1666237A3 (en) * | 2004-10-20 | 2006-10-18 | Fette GmbH | Rotary press |
| JP2008290145A (en) * | 2007-05-28 | 2008-12-04 | Kao Corp | Method for producing tablet |
| KR100972556B1 (en) | 2008-10-13 | 2010-07-28 | 노윤한 | a cleaner for tablet mold |
| JP2011225537A (en) * | 2010-03-31 | 2011-11-10 | Daiichi Sankyo Co Ltd | Production method for solid preparation |
| JP2020018611A (en) * | 2018-08-01 | 2020-02-06 | 沢井製薬株式会社 | Method and device for evaluating binding of tablet |
-
2000
- 2000-10-03 JP JP2000303789A patent/JP2002103096A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1666237A3 (en) * | 2004-10-20 | 2006-10-18 | Fette GmbH | Rotary press |
| JP2008290145A (en) * | 2007-05-28 | 2008-12-04 | Kao Corp | Method for producing tablet |
| KR100972556B1 (en) | 2008-10-13 | 2010-07-28 | 노윤한 | a cleaner for tablet mold |
| JP2011225537A (en) * | 2010-03-31 | 2011-11-10 | Daiichi Sankyo Co Ltd | Production method for solid preparation |
| JP2020018611A (en) * | 2018-08-01 | 2020-02-06 | 沢井製薬株式会社 | Method and device for evaluating binding of tablet |
| JP7048447B2 (en) | 2018-08-01 | 2022-04-05 | 沢井製薬株式会社 | Tablet binding evaluation method and evaluation device |
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