JP2001091421A - Sample storage container - Google Patents

Sample storage container

Info

Publication number
JP2001091421A
JP2001091421A JP26602499A JP26602499A JP2001091421A JP 2001091421 A JP2001091421 A JP 2001091421A JP 26602499 A JP26602499 A JP 26602499A JP 26602499 A JP26602499 A JP 26602499A JP 2001091421 A JP2001091421 A JP 2001091421A
Authority
JP
Japan
Prior art keywords
synthetic resin
sample storage
storage container
gas barrier
barrier property
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP26602499A
Other languages
Japanese (ja)
Inventor
Masahiro Nakaizumi
政博 中泉
Hironobu Isogawa
浩信 五十川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sekisui Chemical Co Ltd
Original Assignee
Sekisui Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sekisui Chemical Co Ltd filed Critical Sekisui Chemical Co Ltd
Priority to JP26602499A priority Critical patent/JP2001091421A/en
Publication of JP2001091421A publication Critical patent/JP2001091421A/en
Pending legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • B29C45/16Making multilayered or multicoloured articles
    • B29C45/1642Making multilayered or multicoloured articles having a "sandwich" structure
    • B29C45/1646Injecting parison-like articles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274Manufacture or production processes or steps for blood sampling devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154Devices using pre-evacuated means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082Test tubes per se
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/142Preventing evaporation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/10Means to control humidity and/or other gases
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2995/00Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
    • B29K2995/0037Other properties
    • B29K2995/0065Permeability to gases
    • B29K2995/0067Permeability to gases non-permeable
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • B29L2031/712Containers; Packaging elements or accessories, Packages

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Manufacturing & Machinery (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Clinical Laboratory Science (AREA)
  • Laminated Bodies (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

PROBLEM TO BE SOLVED: To provide a sample storage container with excellent gas barrier characteristic and water vapor barrier characteristic. SOLUTION: This container is formed by sandwich molding, and one of a skin layer 2 and a core layer 3 is made of a synthetic resin with an excellent gas barrier characteristic, while the other is made of a synthetic resin with an excellent water barrier characteristic.

Description

【発明の詳細な説明】DETAILED DESCRIPTION OF THE INVENTION

【0001】[0001]

【発明の属する技術分野】本発明は、試料収納容器に関
する。
TECHNICAL FIELD The present invention relates to a sample container.

【0002】[0002]

【従来の技術】耐衝撃性に欠ける硝子に代えて、熱可塑
性ポリエステル樹脂を射出成形して製造された血液等の
試料収納容器は、例えば、実公平3−27614号公報
に示されているように、公知である。
2. Description of the Related Art A container for storing a sample such as blood produced by injection molding a thermoplastic polyester resin in place of glass lacking impact resistance is disclosed in, for example, Japanese Utility Model Publication No. 3-27614. Are well known.

【0003】[0003]

【発明が解決しようとする課題】しかしながら、このよ
うな試料収納容器に於いては、ガスバリア性はよいが、
水蒸気バリア性が劣る為、内部に収納された試料の成分
が変質することがあるという問題があった。
However, such a sample storage container has good gas barrier properties,
Since the water vapor barrier property is inferior, there is a problem that the components of the sample stored inside may be deteriorated.

【0004】本発明は、上記従来の問題点を解消し、ガ
スバリア性及び水蒸気バリア性の優れた試料収納容器を
提供することを目的とする。
An object of the present invention is to solve the above-mentioned conventional problems and to provide a sample storage container having excellent gas barrier properties and water vapor barrier properties.

【0005】[0005]

【課題を解決するための手段】請求項1の発明の試料収
納容器は、サンドイッチ成形により成形され、スキン層
とコア層の何れか一方がガスバリア性に優れた合成樹
脂、他方が水蒸気バリア性に優れた合成樹脂からなるこ
とを特徴とする。
The sample container of the present invention is formed by sandwich molding, and one of the skin layer and the core layer is a synthetic resin having excellent gas barrier properties, and the other is a synthetic resin having excellent water vapor barrier properties. It is characterized by being made of an excellent synthetic resin.

【0006】請求項2の発明の試料収納容器は、更に、
スキン層がガスバリア性に優れた合成樹脂、コア層が水
蒸気バリア性に優れた合成樹脂であることを特徴とす
る。
[0006] The sample storage container of the invention according to claim 2 further comprises:
The skin layer is made of a synthetic resin having excellent gas barrier properties, and the core layer is made of a synthetic resin having excellent steam barrier properties.

【0007】請求項3の発明の試料収納容器は、更に、
ガスバリア性に優れた合成樹脂が熱可塑性ポリエステル
樹脂、水蒸気バリア性に優れた合成樹脂がポリオレフィ
ンであることを特徴とする。
[0007] The sample container of the invention according to claim 3 further comprises:
The synthetic resin having an excellent gas barrier property is a thermoplastic polyester resin, and the synthetic resin having an excellent steam barrier property is a polyolefin.

【0008】本発明の試料収納容器に於いて、サンドイ
ッチ成形とは、開割閉合可能な金型のスプルに2台の射
出成形機を接続し、先ずスキン層を形成する合成樹脂を
型窩内に射出した後、ノズルを切換えて同一スプルを通
してコア層を形成する合成樹脂を射出し、最後にゲート
部へ少量のスキン層を形成する合成樹脂を射出してシー
ルし、多層構造の製品を得る成形法である。
In the sample container of the present invention, the sandwich molding means that two injection molding machines are connected to a sprue of a mold which can be opened and closed, and a synthetic resin for forming a skin layer is first placed in the mold cavity. After switching to the nozzle, the synthetic resin forming the core layer is injected through the same sprue by switching the nozzle, and finally the synthetic resin for forming a small amount of the skin layer is injected into the gate portion and sealed to obtain a product having a multilayer structure. It is a molding method.

【0009】本発明の試料収納容器に於いて、ガスバリ
ア性に優れた合成樹脂としては、特に限定されず、例え
ば、ポリエチレンテレフタレート(PET)、ポリエチ
レンナフタレート(PEN)等の熱可塑性ポリエステル
樹脂が好適に使用される。
In the sample container of the present invention, the synthetic resin having excellent gas barrier properties is not particularly limited. For example, a thermoplastic polyester resin such as polyethylene terephthalate (PET) and polyethylene naphthalate (PEN) is preferable. Used for

【0010】試料収納容器をサンドイッチ成形した場
合、コア層を形成する合成樹脂の射出に伴い型窩内の奥
へと充填されて行く際に、先んじて射出されたスキン層
を形成する合成樹脂は延伸されて肉薄となるが、PET
は延伸されると未延伸の場合に比べて酸素透過係数(cc
・mm/m2・24hr・ atm)が 4.0から 2.0と半減するの
で、ガスバリア性が低下しないという利点を有する。
[0010] When the sample container is sandwich-molded, when the synthetic resin forming the core layer is injected into the interior of the mold cavity with the injection of the synthetic resin, the synthetic resin forming the skin layer injected first is It is stretched and becomes thin, but PET
Is the oxygen transmission coefficient (cc
(Mm / m 2 · 24 hr · atm) is halved from 4.0 to 2.0, so that there is an advantage that the gas barrier property does not decrease.

【0011】本発明の試料収納容器に於いて、水蒸気バ
リア性に優れた合成樹脂としては、特に限定されず、例
えば、ポリプロピレン(PP)、高密度ポリエチレン
(HDPE)等のポリオレフィンが好適に使用される。
In the sample container of the present invention, the synthetic resin having excellent water vapor barrier properties is not particularly limited, and for example, polyolefins such as polypropylene (PP) and high density polyethylene (HDPE) are preferably used. You.

【0012】[0012]

【発明の実施の形態】以下本発明の実施例を図面に基い
て説明する。図1は本発明の試料収納容器の1例を示す
断面図、図2乃至図5は図1に示されている本発明の試
料収納容器のサンドイッチ成形による成形段階を示す模
式図である。
Embodiments of the present invention will be described below with reference to the drawings. FIG. 1 is a cross-sectional view showing one example of the sample storage container of the present invention, and FIGS. 2 to 5 are schematic views showing a molding stage of the sample storage container of the present invention shown in FIG. 1 by sandwich molding.

【0013】〔実施例〕図2乃至図5に示すように、開
割閉合可能な金型1、1に2台の射出成形機を接続し、
先ずスキン層2を形成する合成樹脂であるPETを型窩
11内に射出した後、コア層3を形成する合成樹脂である
PPを射出し、最後にスキン層2を形成する合成樹脂で
あるPETを少量ゲート部へ射出してシールして、サン
ドイッチ成形により、図1に示されている、内径14.0m
m、肉厚 1.2mm、長さ 100.0mmの試料収納容器を得た。
[Embodiment] As shown in FIGS. 2 to 5, two injection molding machines are connected to molds 1 and 1 which can be opened and closed.
First, PET, which is a synthetic resin for forming the skin layer 2, is placed in a mold cavity.
After injecting into the inside 11, PP, which is a synthetic resin forming the core layer 3, is injected. Finally, a small amount of PET, which is a synthetic resin forming the skin layer 2, is injected into the gate portion to seal it. 14.0m inside diameter, shown in Figure 1
A sample storage container having a thickness of m, a thickness of 1.2 mm, and a length of 100.0 mm was obtained.

【0014】〔比較例1〕PPを用いることなく、全体
をPETで形成して、実施例と同形同大の試料収納容器
を得た。
[Comparative Example 1] A sample storage container having the same shape and the same size as that of the example was obtained by forming the whole with PET without using PP.

【0015】〔比較例2〕PETを用いることなく、全
体をPPで形成して、実施例と同形同大の試料収納容器
を得た。
[Comparative Example 2] A sample storage container having the same shape and the same size as the example was obtained by forming the whole of PP without using PET.

【0016】前記実施例及び比較例1〜2で得られた試
料収納容器について、内部を60mmHgに減圧してブチル
ゴム製栓により密封して50℃の恒温室に放置し、内部圧
力の経時変化を測定し、ガスバリア性を評価した。
With respect to the sample storage containers obtained in the above Examples and Comparative Examples 1 and 2, the internal pressure was reduced to 60 mmHg, sealed with a butyl rubber stopper, and left in a constant temperature room at 50 ° C. It measured and evaluated the gas barrier property.

【0017】前記実施例及び比較例1〜2で得られた試
料収納容器について、内部に 2.0ccの蒸留水を入れてブ
チルゴム製栓により密封して50℃の恒温室に放置し、内
部の水分の保持量の経時変化を測定し、水蒸気バリア性
を評価した。
The sample storage containers obtained in the above Examples and Comparative Examples 1 and 2 were filled with 2.0 cc of distilled water, sealed with a butyl rubber stopper, and allowed to stand in a constant temperature room at 50 ° C. The change with time of the retained amount of was measured, and the water vapor barrier property was evaluated.

【0018】実施例及び比較例1〜2について行った、
ガスバリア性と水蒸気バリア性についての評価試験の結
果を表1に纏めて示す。
Examples and Comparative Examples 1 and 2 were performed.
Table 1 summarizes the results of evaluation tests on gas barrier properties and water vapor barrier properties.

【0019】[0019]

【表1】 [Table 1]

【0020】表1から明らかな如く、実施例の試料収納
容器は、ガスバリア性、水蒸気バリア性の何れも優れて
いることが判る。
As is evident from Table 1, the sample storage containers of the examples have excellent gas barrier properties and water vapor barrier properties.

【発明の効果】本発明の試料収納容器は、叙上の通り構
成されているので、真空採血管等の試料収納容器として
好適に使用することが出来る。
Since the sample container of the present invention is configured as described above, it can be suitably used as a sample container for a vacuum blood collection tube or the like.

【図面の簡単な説明】[Brief description of the drawings]

【図1】本発明の試料収納容器の1例を示す断面図。FIG. 1 is a sectional view showing an example of a sample storage container according to the present invention.

【図2】図1に示されている本発明の試料収納容器のサ
ンドイッチ成形による第1の成形段階を示す模式図。
FIG. 2 is a schematic diagram showing a first molding stage of the sample storage container of the present invention shown in FIG. 1 by sandwich molding.

【図3】図1に示されている本発明の試料収納容器のサ
ンドイッチ成形による第2の成形段階を示す模式図。
FIG. 3 is a schematic view showing a second molding stage of the sample storage container of the present invention shown in FIG. 1 by sandwich molding.

【図4】図1に示されている本発明の試料収納容器のサ
ンドイッチ成形による第3の成形段階を示す模式図。
FIG. 4 is a schematic view showing a third molding stage of the sample storage container of the present invention shown in FIG. 1 by sandwich molding.

【図5】図1に示されている本発明の試料収納容器のサ
ンドイッチ成形による第4の成形段階を示す模式図。
FIG. 5 is a schematic view showing a fourth molding stage of the sample storage container of the present invention shown in FIG. 1 by sandwich molding.

【符号の説明】[Explanation of symbols]

1 金型 2 スキン層 3 コア層 11 型窩 1 mold 2 skin layer 3 core layer 11 type fossa

フロントページの続き Fターム(参考) 4F100 AK01A AK01B AK01C AK03A AK03C AK07 AK07B AK41A AK41B AK41C AK42 AK62A AK62C AK66A AK66C BA03 BA06 BA10B BA10C BA15 DA01 EH36 GB16 JB16A JB16B JB16C JD02 JD02A JD02B JD02C JD04 JD04A JD04B JD04C Continued on the front page F term (reference) 4F100 AK01A AK01B AK01C AK03A AK03C AK07 AK07B AK41A AK41B AK41C AK42 AK62A AK62C AK66A AK66C BA03 J06 BA10B BA10C BA15 DA01 EH36 GB16 JB16BD J16B02

Claims (3)

【特許請求の範囲】[Claims] 【請求項1】 サンドイッチ成形により成形され、スキ
ン層とコア層の何れか一方がガスバリア性に優れた合成
樹脂、他方が水蒸気バリア性に優れた合成樹脂からなる
ことを特徴とする試料収納容器。
1. A sample container formed by sandwich molding, wherein one of a skin layer and a core layer is made of a synthetic resin having an excellent gas barrier property, and the other is made of a synthetic resin having an excellent water vapor barrier property.
【請求項2】 スキン層がガスバリア性に優れた合成樹
脂、コア層が水蒸気バリア性に優れた合成樹脂である請
求項1に記載の試料収納容器。
2. The sample container according to claim 1, wherein the skin layer is a synthetic resin having an excellent gas barrier property, and the core layer is a synthetic resin having an excellent water vapor barrier property.
【請求項3】 ガスバリア性に優れた合成樹脂が熱可塑
性ポリエステル樹脂、水蒸気バリア性に優れた合成樹脂
がポリオレフィンである請求項1乃至2に記載の試料収
納容器。
3. The sample container according to claim 1, wherein the synthetic resin having an excellent gas barrier property is a thermoplastic polyester resin, and the synthetic resin having an excellent water vapor barrier property is a polyolefin.
JP26602499A 1999-09-20 1999-09-20 Sample storage container Pending JP2001091421A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP26602499A JP2001091421A (en) 1999-09-20 1999-09-20 Sample storage container

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP26602499A JP2001091421A (en) 1999-09-20 1999-09-20 Sample storage container

Publications (1)

Publication Number Publication Date
JP2001091421A true JP2001091421A (en) 2001-04-06

Family

ID=17425335

Family Applications (1)

Application Number Title Priority Date Filing Date
JP26602499A Pending JP2001091421A (en) 1999-09-20 1999-09-20 Sample storage container

Country Status (1)

Country Link
JP (1) JP2001091421A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2305446B1 (en) * 2001-06-18 2018-08-01 Becton, Dickinson and Company Process for forming multilayer containers

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2305446B1 (en) * 2001-06-18 2018-08-01 Becton, Dickinson and Company Process for forming multilayer containers
EP3412424A1 (en) * 2001-06-18 2018-12-12 Becton, Dickinson and Company Blood collection tube

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