JOP20210197A1 - Methods of purifying an allergen extract - Google Patents
Methods of purifying an allergen extractInfo
- Publication number
- JOP20210197A1 JOP20210197A1 JOP/2021/0197A JOP20210197A JOP20210197A1 JO P20210197 A1 JOP20210197 A1 JO P20210197A1 JO P20210197 A JOP20210197 A JO P20210197A JO P20210197 A1 JOP20210197 A1 JO P20210197A1
- Authority
- JO
- Jordan
- Prior art keywords
- allergen extract
- purifying
- methods
- allergen
- purified
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/68—Protozoa, e.g. flagella, amoebas, sporozoans, plasmodium or toxoplasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Insects & Arthropods (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Dermatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
The invention relates to processes for producing semi-purified and purified allergen extracts and pharmaceutical compositions and vaccines for use in the diagnosis and treatment of allergy. In one aspect of the invention, a process for producing a depigmented allergen extract is provided, the process comprising: a) basifying a native allergen extract; and b) removing molecules having a molecular size of less than 3.5 kDa; and c) adjusting the pH to neutrality; thereby to produce a depigmented allergen extract.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP19382030 | 2019-01-17 | ||
PCT/EP2019/057647 WO2020147985A1 (en) | 2019-01-17 | 2019-03-26 | Methods of purifying an allergen extract |
Publications (1)
Publication Number | Publication Date |
---|---|
JOP20210197A1 true JOP20210197A1 (en) | 2023-01-30 |
Family
ID=65279503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2021/0197A JOP20210197A1 (en) | 2019-01-17 | 2019-03-26 | Methods of purifying an allergen extract |
Country Status (16)
Country | Link |
---|---|
US (1) | US20220110983A1 (en) |
EP (1) | EP3911343A1 (en) |
JP (1) | JP2022523647A (en) |
CN (1) | CN113825518A (en) |
AU (1) | AU2019422413A1 (en) |
BR (1) | BR112021014064A2 (en) |
CA (1) | CA3126499A1 (en) |
CL (1) | CL2021001889A1 (en) |
CO (1) | CO2021010606A2 (en) |
CR (1) | CR20210432A (en) |
EC (1) | ECSP21060381A (en) |
IL (1) | IL284901A (en) |
JO (1) | JOP20210197A1 (en) |
MX (1) | MX2021008665A (en) |
PE (1) | PE20212105A1 (en) |
WO (1) | WO2020147985A1 (en) |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0083497A3 (en) * | 1982-01-06 | 1985-11-06 | Beecham Group Plc | Process for preparing modified allergens, their use in treating allergic conditions |
WO1993001213A1 (en) * | 1991-07-12 | 1993-01-21 | Immulogic Pharmaceutical Corporation | Allergenic proteins and peptides from japanese cedar pollen |
JP3124344B2 (en) * | 1991-11-06 | 2001-01-15 | フマキラー株式会社 | Polymerized mite allergen |
JP3397791B2 (en) * | 1992-09-21 | 2003-04-21 | ラボラトリオス レティ ソシエダッド アノニマ | Purification method of aqueous extract containing protein active as allergen, extract obtained by this method and use thereof |
US5770698A (en) | 1992-09-21 | 1998-06-23 | C.B.F. Leti S.A. | Process for the purification of aqueous extracts containing allergenically active proteins, extracts obtainable according to this process as well as their use |
BRPI0313613B1 (en) * | 2002-08-19 | 2016-06-07 | Merck Patent Ges Mit Beschränkter Haftung | variants of the major timothy grass phl p 1 allergen, their folding forms lm and hm, their uses and their preparation and purification processes, DNA molecule, recombinant DNA expression vector and its use, and pharmaceutical compositions |
RU2332986C2 (en) * | 2003-04-04 | 2008-09-10 | Дженентек, Инк. | Highly concentrated compositions of antibodies and proteins |
RU2706685C2 (en) * | 2010-02-12 | 2019-11-20 | Лабораториос Лети, С.Л. | Method of producing allergen extract |
FI20115374A0 (en) * | 2011-04-18 | 2011-04-18 | Teknologian Tutkimuskeskus Vtt Oy | New hypoallergens |
CN102552900A (en) * | 2011-12-21 | 2012-07-11 | 北京新华联协和药业有限责任公司 | Artemisia pollen allergen vaccine, and preparation method and application thereof |
CN103966292A (en) * | 2013-01-31 | 2014-08-06 | 中国食品发酵工业研究院 | Industrial manufacturing method and use of allergen-eliminated partly appropriately-hydrolyzed casein peptide |
ES2503516B1 (en) * | 2013-04-03 | 2015-09-09 | Inmunotek, S.L. | IMMUNOGENIC COMPLEX FOR VACCINATION AND METHOD OF OBTAINING |
-
2019
- 2019-03-26 BR BR112021014064-6A patent/BR112021014064A2/en unknown
- 2019-03-26 AU AU2019422413A patent/AU2019422413A1/en active Pending
- 2019-03-26 EP EP19713033.9A patent/EP3911343A1/en active Pending
- 2019-03-26 JO JOP/2021/0197A patent/JOP20210197A1/en unknown
- 2019-03-26 US US17/423,585 patent/US20220110983A1/en active Pending
- 2019-03-26 JP JP2021541631A patent/JP2022523647A/en active Pending
- 2019-03-26 MX MX2021008665A patent/MX2021008665A/en unknown
- 2019-03-26 PE PE2021001195A patent/PE20212105A1/en unknown
- 2019-03-26 WO PCT/EP2019/057647 patent/WO2020147985A1/en active Application Filing
- 2019-03-26 CR CR20210432A patent/CR20210432A/en unknown
- 2019-03-26 CA CA3126499A patent/CA3126499A1/en active Pending
- 2019-03-26 CN CN201980092803.5A patent/CN113825518A/en active Pending
-
2021
- 2021-07-15 IL IL284901A patent/IL284901A/en unknown
- 2021-07-15 CL CL2021001889A patent/CL2021001889A1/en unknown
- 2021-08-12 CO CONC2021/0010606A patent/CO2021010606A2/en unknown
- 2021-08-16 EC ECSENADI202160381A patent/ECSP21060381A/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP3911343A1 (en) | 2021-11-24 |
IL284901A (en) | 2021-08-31 |
CR20210432A (en) | 2022-01-05 |
JP2022523647A (en) | 2022-04-26 |
PE20212105A1 (en) | 2021-11-04 |
US20220110983A1 (en) | 2022-04-14 |
MX2021008665A (en) | 2021-10-26 |
CN113825518A (en) | 2021-12-21 |
CL2021001889A1 (en) | 2022-01-21 |
AU2019422413A1 (en) | 2021-08-26 |
CA3126499A1 (en) | 2020-07-23 |
WO2020147985A1 (en) | 2020-07-23 |
ECSP21060381A (en) | 2021-11-18 |
BR112021014064A2 (en) | 2021-09-21 |
CO2021010606A2 (en) | 2021-10-29 |
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